GALNT11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1aminoglycoside antibiotic metabolic process (GO:0030647)9.79351240
2drug transmembrane transport (GO:0006855)9.35351375
3urate metabolic process (GO:0046415)9.28001245
4drug transport (GO:0015893)7.88874619
5organic cation transport (GO:0015695)7.79908193
6phosphate ion transport (GO:0006817)7.39074521
7lysine catabolic process (GO:0006554)7.05081382
8lysine metabolic process (GO:0006553)7.05081382
9phosphate ion transmembrane transport (GO:0035435)5.97039004
10quaternary ammonium group transport (GO:0015697)5.93314936
11excretion (GO:0007588)5.77294586
12metanephric nephron tubule development (GO:0072234)5.73426423
13metanephric tubule development (GO:0072170)5.73426423
14response to mercury ion (GO:0046689)5.56559882
15drug catabolic process (GO:0042737)5.46626184
16glyoxylate metabolic process (GO:0046487)5.39182990
17tricarboxylic acid metabolic process (GO:0072350)5.32429529
18toxin transport (GO:1901998)5.27910467
19exogenous drug catabolic process (GO:0042738)5.24563117
20metanephric nephron epithelium development (GO:0072243)5.24519955
21nonribosomal peptide biosynthetic process (GO:0019184)5.17166678
22renal absorption (GO:0070293)5.13725419
23short-chain fatty acid metabolic process (GO:0046459)5.03907162
24cysteine metabolic process (GO:0006534)5.03137258
25vitamin D metabolic process (GO:0042359)4.95982504
26metanephric epithelium development (GO:0072207)4.86489034
27synaptic vesicle maturation (GO:0016188)4.85778456
28trivalent inorganic anion homeostasis (GO:0072506)4.81233933
29phosphate ion homeostasis (GO:0055062)4.81233933
30branched-chain amino acid metabolic process (GO:0009081)4.76423726
31glycoside metabolic process (GO:0016137)4.68439343
32aspartate family amino acid catabolic process (GO:0009068)4.67077655
33nephron tubule development (GO:0072080)4.56891934
34glutathione biosynthetic process (GO:0006750)4.46797279
35glutamate secretion (GO:0014047)4.41623443
36indole-containing compound catabolic process (GO:0042436)4.40146011
37indolalkylamine catabolic process (GO:0046218)4.40146011
38tryptophan catabolic process (GO:0006569)4.40146011
39homocysteine metabolic process (GO:0050667)4.36221273
40amino-acid betaine transport (GO:0015838)4.26604554
41carnitine transport (GO:0015879)4.26604554
42tryptophan metabolic process (GO:0006568)4.26306038
43aromatic amino acid family catabolic process (GO:0009074)4.24417843
44valine metabolic process (GO:0006573)4.19410207
45renal tubule development (GO:0061326)4.12274268
46regulation of short-term neuronal synaptic plasticity (GO:0048172)4.12238861
47synaptic vesicle exocytosis (GO:0016079)4.09688231
48modified amino acid transport (GO:0072337)4.08899617
49polyol transport (GO:0015791)4.08852701
50oligosaccharide catabolic process (GO:0009313)4.07802942
512-oxoglutarate metabolic process (GO:0006103)4.03779709
52peptide biosynthetic process (GO:0043043)4.01989590
53synaptic vesicle docking involved in exocytosis (GO:0016081)4.00948126
54branched-chain amino acid catabolic process (GO:0009083)3.91476158
55fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.89959158
56erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.88143098
57L-phenylalanine catabolic process (GO:0006559)3.88143098
58proline metabolic process (GO:0006560)3.87488341
59neuron cell-cell adhesion (GO:0007158)3.85893057
60neurotransmitter-gated ion channel clustering (GO:0072578)3.80756540
61pyrimidine nucleobase catabolic process (GO:0006208)3.79380645
62regulation of synaptic vesicle transport (GO:1902803)3.78811012
63nephron epithelium development (GO:0072009)3.78370425
64erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.77313599
65L-phenylalanine metabolic process (GO:0006558)3.77313599
66axonal fasciculation (GO:0007413)3.77011938
67regulation of synaptic vesicle exocytosis (GO:2000300)3.72976862
68cellular modified amino acid catabolic process (GO:0042219)3.68234351
69fatty acid beta-oxidation (GO:0006635)3.67982262
70regulation of synapse structural plasticity (GO:0051823)3.67407996
71cellular ketone body metabolic process (GO:0046950)3.65459313
72postsynaptic membrane organization (GO:0001941)3.65192884
73indole-containing compound metabolic process (GO:0042430)3.64412274
74response to phenylpropanoid (GO:0080184)3.60446299
75protein localization to synapse (GO:0035418)3.60374555
76peptide catabolic process (GO:0043171)3.58385834
77nephron tubule morphogenesis (GO:0072078)3.58176157
78nephron epithelium morphogenesis (GO:0072088)3.58176157
79fructose metabolic process (GO:0006000)3.55791599
80neuron recognition (GO:0008038)3.52533708
81vocalization behavior (GO:0071625)3.50160340
82amino-acid betaine metabolic process (GO:0006577)3.49482863
83serine family amino acid catabolic process (GO:0009071)3.47456586
84response to parathyroid hormone (GO:0071107)3.46557893
85positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.43892258
86sodium ion transport (GO:0006814)3.42646923
87fatty acid oxidation (GO:0019395)3.42541448
88neuronal ion channel clustering (GO:0045161)3.42013289
89lipid oxidation (GO:0034440)3.36456412
90acetyl-CoA metabolic process (GO:0006084)3.35770187
91indolalkylamine metabolic process (GO:0006586)3.32504957
92carnitine metabolic process (GO:0009437)3.26529961
93cellular response to vitamin D (GO:0071305)3.26045192
94pyrimidine ribonucleoside catabolic process (GO:0046133)3.25658601
95beta-amyloid metabolic process (GO:0050435)3.24994027
96positive regulation of vesicle fusion (GO:0031340)3.24528490
97polyol catabolic process (GO:0046174)3.24040456
98presynaptic membrane assembly (GO:0097105)3.23061123
99glutamate metabolic process (GO:0006536)3.22033036
100negative regulation of synaptic transmission, GABAergic (GO:0032229)3.20804220
101sulfur compound transport (GO:0072348)3.19979206
102vitamin transport (GO:0051180)3.19388347
103serine family amino acid metabolic process (GO:0009069)3.17145683
104renal tubule morphogenesis (GO:0061333)3.15243783
105ionotropic glutamate receptor signaling pathway (GO:0035235)3.14074702
106ketone body metabolic process (GO:1902224)3.12573727
107aromatic amino acid family metabolic process (GO:0009072)3.11539244
108kynurenine metabolic process (GO:0070189)3.11191743
109negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.09406582
110sodium-independent organic anion transport (GO:0043252)3.08682342
111positive regulation of mitochondrial fission (GO:0090141)3.05848323
112presynaptic membrane organization (GO:0097090)3.05447117
113cobalamin metabolic process (GO:0009235)3.04912640
114biotin metabolic process (GO:0006768)3.04394406
115neurotransmitter secretion (GO:0007269)3.03189125
116cellular potassium ion homeostasis (GO:0030007)3.02850833
117response to magnesium ion (GO:0032026)3.02148889
118establishment of mitochondrion localization (GO:0051654)3.01508032
119dopamine biosynthetic process (GO:0042416)3.01356941
120amine catabolic process (GO:0009310)3.01336669
121cellular biogenic amine catabolic process (GO:0042402)3.01336669
122nucleobase catabolic process (GO:0046113)3.01259791
123cell migration in hindbrain (GO:0021535)3.01194001
124positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.01004795
125positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.00298969
126regulation of vesicle fusion (GO:0031338)3.00286232
127fatty acid catabolic process (GO:0009062)2.99951974
128cellular amino acid catabolic process (GO:0009063)2.96389928
129response to growth hormone (GO:0060416)2.95989138
130auditory behavior (GO:0031223)2.95315978
131positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.94933668
132membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.93246275
133synapse assembly (GO:0007416)2.92290148
134synaptic transmission, glutamatergic (GO:0035249)2.90501450
135regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.90369660
136dendrite morphogenesis (GO:0048813)2.89481763
137fat-soluble vitamin catabolic process (GO:0042363)2.89251164
138vitamin catabolic process (GO:0009111)2.89251164
139axon extension (GO:0048675)2.88670475
140neurotransmitter biosynthetic process (GO:0042136)2.88643508
141alpha-amino acid catabolic process (GO:1901606)2.85017178
142sodium ion export (GO:0071436)2.78005833
143regulation of clathrin-mediated endocytosis (GO:2000369)2.75630451
144calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.74597588
145locomotory exploration behavior (GO:0035641)2.74162977
146neuron-neuron synaptic transmission (GO:0007270)2.73797618
147mating behavior (GO:0007617)2.71682187
148regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.67331883
149gamma-aminobutyric acid transport (GO:0015812)2.67310244
150layer formation in cerebral cortex (GO:0021819)2.66726667
151positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.66519995
152neuron projection extension (GO:1990138)2.62573515
153regulation of neuronal synaptic plasticity (GO:0048168)2.59514309
154neurotransmitter transport (GO:0006836)2.57692587
155regulation of neurotransmitter levels (GO:0001505)2.56930778
156glutamate receptor signaling pathway (GO:0007215)2.56881887
157positive regulation of synapse assembly (GO:0051965)2.55111554
158dopamine transport (GO:0015872)2.51480222
159regulation of glutamate receptor signaling pathway (GO:1900449)2.50807835
160exploration behavior (GO:0035640)2.50347989
161detection of calcium ion (GO:0005513)2.50138468
162synaptic vesicle endocytosis (GO:0048488)2.50022256
163negative regulation of cytosolic calcium ion concentration (GO:0051481)2.49557029
164macroautophagy (GO:0016236)2.48826701
165synapse organization (GO:0050808)2.48766939
166establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.47255754
167mitochondrion transport along microtubule (GO:0047497)2.47255754
168regulation of dopamine secretion (GO:0014059)2.47131641
169cerebellar granule cell differentiation (GO:0021707)2.44545930
170dendritic spine organization (GO:0097061)2.43857824
171regulation of neurotransmitter secretion (GO:0046928)2.43492323
172regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.41895646
173regulation of cAMP-dependent protein kinase activity (GO:2000479)2.41771774
174activation of protein kinase A activity (GO:0034199)2.40079437
175negative regulation of neurotransmitter transport (GO:0051589)2.39837576
176regulation of neurotransmitter transport (GO:0051588)2.38149860
177cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.37555328
178response to manganese ion (GO:0010042)2.37136233
179organelle transport along microtubule (GO:0072384)2.36914542
180regulation of long-term neuronal synaptic plasticity (GO:0048169)2.36628042
181positive regulation of catecholamine secretion (GO:0033605)2.35403586
182adult walking behavior (GO:0007628)2.34490958
183long-term memory (GO:0007616)2.32852087
184response to auditory stimulus (GO:0010996)2.31150974
185suckling behavior (GO:0001967)2.27660927
186cell communication by electrical coupling (GO:0010644)2.27292077
187regulation of synapse assembly (GO:0051963)2.26511299
188neuronal action potential propagation (GO:0019227)2.26386603
189regulation of synaptic transmission, GABAergic (GO:0032228)2.26032383
190synaptic vesicle transport (GO:0048489)2.25966779
191establishment of synaptic vesicle localization (GO:0097480)2.25966779
192neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.25140911
193positive regulation of membrane potential (GO:0045838)2.23940502
194establishment of vesicle localization (GO:0051650)2.23699941
195glycosphingolipid biosynthetic process (GO:0006688)2.22843924
196regulation of synaptic transmission, glutamatergic (GO:0051966)2.22304511

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.50057227
2EZH2_22144423_ChIP-Seq_EOC_Human3.17990550
3ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.87697782
4NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.76159809
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.73832552
6CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.68462498
7VDR_22108803_ChIP-Seq_LS180_Human2.51344536
8ESR1_21235772_ChIP-Seq_MCF-7_Human2.16546650
9PIAS1_25552417_ChIP-Seq_VCAP_Human2.06725658
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.02172764
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.98240469
12IGF1R_20145208_ChIP-Seq_DFB_Human1.96172380
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.92089881
14JARID2_20064375_ChIP-Seq_MESCs_Mouse1.90561983
15CDX2_19796622_ChIP-Seq_MESCs_Mouse1.86876280
16MTF2_20144788_ChIP-Seq_MESCs_Mouse1.82049020
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.80789995
18WT1_19549856_ChIP-ChIP_CCG9911_Human1.74874153
19CBX2_27304074_Chip-Seq_ESCs_Mouse1.70586000
20REST_21632747_ChIP-Seq_MESCs_Mouse1.69689998
21ZFP57_27257070_Chip-Seq_ESCs_Mouse1.68741941
22RXR_22158963_ChIP-Seq_LIVER_Mouse1.67215242
23EED_16625203_ChIP-ChIP_MESCs_Mouse1.64444721
24PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.60256382
25EZH2_18974828_ChIP-Seq_MESCs_Mouse1.59636235
26RNF2_18974828_ChIP-Seq_MESCs_Mouse1.59636235
27SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.58195288
28EZH2_27304074_Chip-Seq_ESCs_Mouse1.58056947
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57268698
30* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.56691347
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.54707377
32PCGF2_27294783_Chip-Seq_NPCs_Mouse1.53763202
33JARID2_20075857_ChIP-Seq_MESCs_Mouse1.53598467
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.53129603
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.52546610
36SUZ12_27294783_Chip-Seq_ESCs_Mouse1.47976726
37TAF15_26573619_Chip-Seq_HEK293_Human1.47851757
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.46134034
39RNF2_27304074_Chip-Seq_NSC_Mouse1.45359910
40AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.44911590
41SMAD4_21799915_ChIP-Seq_A2780_Human1.44738992
42ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.43548402
43P300_19829295_ChIP-Seq_ESCs_Human1.42508829
44RARB_27405468_Chip-Seq_BRAIN_Mouse1.41126370
45EZH2_27294783_Chip-Seq_ESCs_Mouse1.40580063
46CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.39185063
47MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.38326336
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38280808
49DROSHA_22980978_ChIP-Seq_HELA_Human1.37783429
50* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.37064960
51AR_21572438_ChIP-Seq_LNCaP_Human1.35361344
52TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34405775
53BMI1_23680149_ChIP-Seq_NPCS_Mouse1.34337282
54LXR_22158963_ChIP-Seq_LIVER_Mouse1.34081940
55SUZ12_27294783_Chip-Seq_NPCs_Mouse1.32393200
56ESR2_21235772_ChIP-Seq_MCF-7_Human1.32212103
57SMAD3_21741376_ChIP-Seq_HESCs_Human1.32195906
58YAP1_20516196_ChIP-Seq_MESCs_Mouse1.32145623
59* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29999061
60FUS_26573619_Chip-Seq_HEK293_Human1.26730118
61TP53_18474530_ChIP-ChIP_U2OS_Human1.26647197
62TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26538248
63POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25190748
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.24516494
65FLI1_27457419_Chip-Seq_LIVER_Mouse1.22793456
66* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.19866963
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.19598316
68OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19324098
69* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.18862280
70TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.18723440
71EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.18708909
72TRIM28_21343339_ChIP-Seq_HEK293_Human1.18563418
73NANOG_18555785_Chip-Seq_ESCs_Mouse1.18531552
74EZH2_27294783_Chip-Seq_NPCs_Mouse1.17935477
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17650559
76PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16542853
77SMAD_19615063_ChIP-ChIP_OVARY_Human1.15850721
78ESR1_20079471_ChIP-ChIP_T-47D_Human1.15630906
79AHR_22903824_ChIP-Seq_MCF-7_Human1.15061038
80KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14196246
81SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13905875
82* SMAD4_21741376_ChIP-Seq_HESCs_Human1.13641763
83EP300_21415370_ChIP-Seq_HL-1_Mouse1.13443591
84RXR_22108803_ChIP-Seq_LS180_Human1.12916068
85ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12570666
86NR3C1_23031785_ChIP-Seq_PC12_Mouse1.12332594
87BCAT_22108803_ChIP-Seq_LS180_Human1.10871068
88SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10330621
89KDM2B_26808549_Chip-Seq_REH_Human1.10130552
90FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.10093616
91CDX2_20551321_ChIP-Seq_CACO-2_Human1.09879125
92AR_25329375_ChIP-Seq_VCAP_Human1.09775746
93* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.08360282
94* TP53_16413492_ChIP-PET_HCT116_Human1.08043567
95TCF4_22108803_ChIP-Seq_LS180_Human1.07835158
96* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.07818565
97PRDM14_20953172_ChIP-Seq_ESCs_Human1.07803299
98P53_22387025_ChIP-Seq_ESCs_Mouse1.06660603
99STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.06388481
100* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05752747
101SMAD3_21741376_ChIP-Seq_EPCs_Human1.04984973
102ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.04659996
103EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04467248
104SOX9_26525672_Chip-Seq_HEART_Mouse1.04446875
105STAT3_23295773_ChIP-Seq_U87_Human1.03902667
106AR_19668381_ChIP-Seq_PC3_Human1.03869609
107E2F1_18555785_Chip-Seq_ESCs_Mouse1.03390261
108RING1B_27294783_Chip-Seq_ESCs_Mouse1.03112764
109NFE2_27457419_Chip-Seq_LIVER_Mouse1.02711278
110UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02392550
111SUZ12_18555785_Chip-Seq_ESCs_Mouse1.01876077
112PPARA_22158963_ChIP-Seq_LIVER_Mouse1.01066326
113CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99591053
114BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99439870
115OCT4_18555785_Chip-Seq_ESCs_Mouse0.99273555
116RUNX2_22187159_ChIP-Seq_PCA_Human0.98943958
117ISL1_27105846_Chip-Seq_CPCs_Mouse0.98745833
118JUN_21703547_ChIP-Seq_K562_Human0.98569438
119PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.98567393
120TCF4_23295773_ChIP-Seq_U87_Human0.98206578
121RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.98107129
122NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98095668
123* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98068729
124TAL1_26923725_Chip-Seq_HPCs_Mouse0.97912528
125RNF2_27304074_Chip-Seq_ESCs_Mouse0.97892372
126ESRRB_18555785_Chip-Seq_ESCs_Mouse0.97189612
127NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97035810
128NRF2_20460467_ChIP-Seq_MEFs_Mouse0.96794524
129NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.96794524
130EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.96655275
131STAT3_18555785_Chip-Seq_ESCs_Mouse0.96597924
132KLF4_18555785_Chip-Seq_ESCs_Mouse0.94937652
133MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94571735
134CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94441034
135* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94332317
136SOX2_18555785_Chip-Seq_ESCs_Mouse0.94300941
137CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93566685
138TBX3_20139965_ChIP-Seq_MESCs_Mouse0.91068878

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004043_abnormal_pH_regulation6.81141386
2MP0005360_urolithiasis6.49090268
3MP0003195_calcinosis4.83509328
4MP0004019_abnormal_vitamin_homeostasis4.61553234
5MP0005332_abnormal_amino_acid4.43416256
6MP0001765_abnormal_ion_homeostasis4.01829305
7MP0002138_abnormal_hepatobiliary_system3.67213334
8MP0009643_abnormal_urine_homeostasis3.66183131
9MP0004270_analgesia3.38936579
10MP0003880_abnormal_central_pattern3.22784087
11MP0002139_abnormal_hepatobiliary_system3.09658984
12MP0001756_abnormal_urination3.02744574
13MP0005636_abnormal_mineral_homeostasis2.90099846
14MP0005377_hearing/vestibular/ear_phenot2.89106279
15MP0003878_abnormal_ear_physiology2.89106279
16MP0002136_abnormal_kidney_physiology2.73638824
17MP0001984_abnormal_olfaction2.44734504
18MP0001958_emphysema2.39881092
19MP0002822_catalepsy2.22715871
20MP0006276_abnormal_autonomic_nervous2.21767122
21MP0008961_abnormal_basal_metabolism2.19440821
22MP0003329_amyloid_beta_deposits2.18731180
23MP0004885_abnormal_endolymph2.17228394
24MP0005423_abnormal_somatic_nervous2.11574555
25MP0003252_abnormal_bile_duct2.07950376
26MP0008875_abnormal_xenobiotic_pharmacok2.07137848
27MP0002572_abnormal_emotion/affect_behav1.97617257
28MP0000538_abnormal_urinary_bladder1.96749131
29MP0002272_abnormal_nervous_system1.88739887
30MP0002909_abnormal_adrenal_gland1.79871631
31MP0003283_abnormal_digestive_organ1.74837781
32MP0002734_abnormal_mechanical_nocicepti1.70524279
33MP0004272_abnormal_basement_membrane1.66874362
34MP0005058_abnormal_lysosome_morphology1.66506322
35MP0005248_abnormal_Harderian_gland1.63489058
36MP0005187_abnormal_penis_morphology1.61772820
37MP0002876_abnormal_thyroid_physiology1.60315980
38MP0001968_abnormal_touch/_nociception1.58841035
39MP0005171_absent_coat_pigmentation1.58828131
40MP0005365_abnormal_bile_salt1.56702462
41MP0005451_abnormal_body_composition1.52158763
42MP0000955_abnormal_spinal_cord1.51629997
43MP0001905_abnormal_dopamine_level1.51459501
44MP0000230_abnormal_systemic_arterial1.50455420
45MP0004811_abnormal_neuron_physiology1.45352193
46MP0003172_abnormal_lysosome_physiology1.45104783
47MP0005670_abnormal_white_adipose1.43931137
48MP0003632_abnormal_nervous_system1.42350890
49MP0002928_abnormal_bile_duct1.39923233
50MP0002168_other_aberrant_phenotype1.36682303
51MP0001299_abnormal_eye_distance/1.36487291
52MP0002882_abnormal_neuron_morphology1.36291436
53MP0003631_nervous_system_phenotype1.34576195
54MP0001529_abnormal_vocalization1.34442835
55MP0001501_abnormal_sleep_pattern1.33993429
56MP0002638_abnormal_pupillary_reflex1.33542286
57MP0004924_abnormal_behavior1.32130542
58MP0005386_behavior/neurological_phenoty1.32130542
59MP0002557_abnormal_social/conspecific_i1.29885942
60MP0005584_abnormal_enzyme/coenzyme_acti1.29052106
61MP0001661_extended_life_span1.27693543
62MP0000751_myopathy1.25616010
63MP0003690_abnormal_glial_cell1.25557381
64MP0005535_abnormal_body_temperature1.24104007
65MP0010386_abnormal_urinary_bladder1.20050461
66MP0001188_hyperpigmentation1.16550345
67MP0002653_abnormal_ependyma_morphology1.14677016
68MP0004742_abnormal_vestibular_system1.13111176
69MP0005084_abnormal_gallbladder_morpholo1.12663565
70MP0002184_abnormal_innervation1.12070081
71MP0004233_abnormal_muscle_weight1.11244216
72MP0005085_abnormal_gallbladder_physiolo1.10984285
73MP0003385_abnormal_body_wall1.10511143
74MP0010030_abnormal_orbit_morphology1.08332566
75MP0001177_atelectasis1.06484720
76MP0001970_abnormal_pain_threshold1.04795048
77MP0000516_abnormal_urinary_system1.04359623
78MP0005367_renal/urinary_system_phenotyp1.04359623
79MP0005623_abnormal_meninges_morphology1.02143629
80MP0002295_abnormal_pulmonary_circulatio1.01931915
81MP0002152_abnormal_brain_morphology1.01258827
82MP0000678_abnormal_parathyroid_gland0.99318356
83MP0000534_abnormal_ureter_morphology0.98435450
84MP0003122_maternal_imprinting0.98361125
85MP0003634_abnormal_glial_cell0.98188772
86MP0008438_abnormal_cutaneous_collagen0.97898004
87MP0002896_abnormal_bone_mineralization0.97821922
88MP0000604_amyloidosis0.96310590
89MP0002733_abnormal_thermal_nociception0.95504078
90MP0008569_lethality_at_weaning0.94751375
91MP0003183_abnormal_peptide_metabolism0.94105253
92MP0000749_muscle_degeneration0.94044287
93MP0002135_abnormal_kidney_morphology0.92834916
94MP0010368_abnormal_lymphatic_system0.92414340
95MP0005220_abnormal_exocrine_pancreas0.91530911
96MP0009780_abnormal_chondrocyte_physiolo0.91353983
97MP0002229_neurodegeneration0.91236942
98MP0003959_abnormal_lean_body0.90099733
99MP0003879_abnormal_hair_cell0.89000242
100MP0003300_gastrointestinal_ulcer0.88391027
101MP0001879_abnormal_lymphatic_vessel0.87736994
102MP0000013_abnormal_adipose_tissue0.84856377
103MP0000647_abnormal_sebaceous_gland0.84694580
104MP0004147_increased_porphyrin_level0.81785107
105MP0000537_abnormal_urethra_morphology0.81467039
106MP0009046_muscle_twitch0.80754635
107MP0005551_abnormal_eye_electrophysiolog0.80568190
108MP0001963_abnormal_hearing_physiology0.80326200
109MP0004085_abnormal_heartbeat0.80309338
110MP0005394_taste/olfaction_phenotype0.79771979
111MP0005499_abnormal_olfactory_system0.79771979
112MP0001485_abnormal_pinna_reflex0.79306214
113MP0004133_heterotaxia0.79276351
114MP0002752_abnormal_somatic_nervous0.78883456
115MP0002069_abnormal_eating/drinking_beha0.77899164
116MP0002067_abnormal_sensory_capabilities0.77285163
117MP0004145_abnormal_muscle_electrophysio0.77040827
118MP0005666_abnormal_adipose_tissue0.76211117
119MP0005645_abnormal_hypothalamus_physiol0.74046736
120MP0005167_abnormal_blood-brain_barrier0.73958194
121MP0003137_abnormal_impulse_conducting0.73635719
122MP0000569_abnormal_digit_pigmentation0.72247342
123MP0005319_abnormal_enzyme/_coenzyme0.71253221
124MP0001664_abnormal_digestion0.70743842
125MP0002233_abnormal_nose_morphology0.70728708
126MP0001764_abnormal_homeostasis0.70309838
127MP0001270_distended_abdomen0.70226832
128MP0003186_abnormal_redox_activity0.69898912
129MP0005503_abnormal_tendon_morphology0.69862122
130MP0001944_abnormal_pancreas_morphology0.69457096
131MP0001486_abnormal_startle_reflex0.69226781
132MP0002735_abnormal_chemical_nociception0.69071727
133MP0001346_abnormal_lacrimal_gland0.68085404
134MP0004858_abnormal_nervous_system0.68020629
135MP0000026_abnormal_inner_ear0.67890939
136MP0002064_seizures0.67317829
137MP0000750_abnormal_muscle_regeneration0.67287850
138MP0002089_abnormal_postnatal_growth/wei0.67195708
139MP0002078_abnormal_glucose_homeostasis0.66652469
140MP0003953_abnormal_hormone_level0.66417230
141MP0003938_abnormal_ear_development0.64709109
142MP0000371_diluted_coat_color0.64131151
143MP0009642_abnormal_blood_homeostasis0.63744141
144MP0002118_abnormal_lipid_homeostasis0.62693619
145MP0004264_abnormal_extraembryonic_tissu0.62367642
146MP0006036_abnormal_mitochondrial_physio0.62065561
147MP0003638_abnormal_response/metabolism_0.59301587
148MP0009745_abnormal_behavioral_response0.57499971
149MP0005395_other_phenotype0.57211890
150MP0001666_abnormal_nutrient_absorption0.54535875
151MP0001502_abnormal_circadian_rhythm0.53408909
152MP0004859_abnormal_synaptic_plasticity0.50761761
153MP0002837_dystrophic_cardiac_calcinosis0.49744596
154MP0004484_altered_response_of0.49655296
155MP0005646_abnormal_pituitary_gland0.49642475
156MP0003635_abnormal_synaptic_transmissio0.49323278
157MP0000920_abnormal_myelination0.49049623
158MP0000778_abnormal_nervous_system0.47488952
159MP0000163_abnormal_cartilage_morphology0.47265089
160MP0000747_muscle_weakness0.47237947
161MP0002115_abnormal_skeleton_extremities0.46663952
162MP0002736_abnormal_nociception_after0.45099249
163MP0000631_abnormal_neuroendocrine_gland0.45055545
164MP0002998_abnormal_bone_remodeling0.44577003
165MP0003795_abnormal_bone_structure0.44271395
166MP0001440_abnormal_grooming_behavior0.43633336
167MP0003136_yellow_coat_color0.43476725
168MP0004142_abnormal_muscle_tone0.41962835
169MP0002066_abnormal_motor_capabilities/c0.41876172
170MP0005409_darkened_coat_color0.41640625
171MP0002063_abnormal_learning/memory/cond0.41378621
172MP0003633_abnormal_nervous_system0.40574825

Predicted human phenotypes

RankGene SetZ-score
1Increased circulating renin level (HP:0000848)8.28744075
2Metabolic alkalosis (HP:0200114)7.68977068
3Hypokalemic alkalosis (HP:0001949)7.41551898
4Hypomagnesemia (HP:0002917)7.41522921
5Hyperactive renin-angiotensin system (HP:0000841)7.02400949
6Polyuria (HP:0000103)6.75395084
7Abnormality of chloride homeostasis (HP:0011422)6.50551860
8Gout (HP:0001997)6.45581194
9Abnormal urine output (HP:0012590)6.27176243
10Abnormality of magnesium homeostasis (HP:0004921)6.13611665
11Abnormality of renal excretion (HP:0011036)5.90671074
12Abnormal drinking behavior (HP:0030082)5.63467679
13Polydipsia (HP:0001959)5.63467679
14Tetany (HP:0001281)5.41718407
15Abnormality of renin-angiotensin system (HP:0000847)5.23156890
16Proximal tubulopathy (HP:0000114)5.15272111
17Hyperaldosteronism (HP:0000859)5.02455236
18Limb dystonia (HP:0002451)4.88774550
19Increased purine levels (HP:0004368)4.73859674
20Hyperuricemia (HP:0002149)4.73859674
21Renal salt wasting (HP:0000127)4.73610897
22Alkalosis (HP:0001948)4.66963747
23Hypercalciuria (HP:0002150)4.21163608
24Hyperglycinuria (HP:0003108)4.19062282
25Abnormality of glutamine family amino acid metabolism (HP:0010902)4.16895973
26Generalized aminoaciduria (HP:0002909)4.04481741
27Hypokalemia (HP:0002900)4.03462397
28Abnormality of purine metabolism (HP:0004352)4.02477209
29Ketoacidosis (HP:0001993)3.93890784
30Myokymia (HP:0002411)3.65173575
31Renal tubular acidosis (HP:0001947)3.55042340
32Supranuclear gaze palsy (HP:0000605)3.49374486
33Action tremor (HP:0002345)3.47248131
34Abnormality of potassium homeostasis (HP:0011042)3.46715677
35Abnormality of the lower motor neuron (HP:0002366)3.46036334
36Abnormality of glycine metabolism (HP:0010895)3.40932496
37Abnormality of serine family amino acid metabolism (HP:0010894)3.40932496
38Focal motor seizures (HP:0011153)3.38954181
39Glycosuria (HP:0003076)3.36674060
40Abnormality of urine glucose concentration (HP:0011016)3.36674060
41Gait imbalance (HP:0002141)3.20680243
42Ketosis (HP:0001946)3.16617617
43Nephrocalcinosis (HP:0000121)3.10069401
44Focal seizures (HP:0007359)2.98884378
45Neurofibrillary tangles (HP:0002185)2.98701547
46Hyperphosphaturia (HP:0003109)2.93993935
47Abnormal urine phosphate concentration (HP:0012599)2.93961290
48Abnormality of nucleobase metabolism (HP:0010932)2.84596780
49Delayed epiphyseal ossification (HP:0002663)2.84232937
50Abnormality of proline metabolism (HP:0010907)2.83096609
51Hydroxyprolinuria (HP:0003080)2.83096609
52Drooling (HP:0002307)2.82929445
53Ankle clonus (HP:0011448)2.82725181
54Congenital primary aphakia (HP:0007707)2.80928752
55Postural instability (HP:0002172)2.77062744
56Hypophosphatemia (HP:0002148)2.76353546
57Nephrogenic diabetes insipidus (HP:0009806)2.70998951
58Febrile seizures (HP:0002373)2.68670709
59Widely patent fontanelles and sutures (HP:0004492)2.67141736
60Enlarged kidneys (HP:0000105)2.66344114
61Nephrolithiasis (HP:0000787)2.63733331
62Dysdiadochokinesis (HP:0002075)2.57754847
63Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.57187344
64Progressive cerebellar ataxia (HP:0002073)2.54200876
65Urinary urgency (HP:0000012)2.54080627
66Cerebral inclusion bodies (HP:0100314)2.53964816
67Truncal ataxia (HP:0002078)2.53262594
68Amyotrophic lateral sclerosis (HP:0007354)2.52974813
69Excessive salivation (HP:0003781)2.50185027
70Abnormality of the corticospinal tract (HP:0002492)2.50026943
71Atonic seizures (HP:0010819)2.47761369
72Vacuolated lymphocytes (HP:0001922)2.46194638
73Hypokinesia (HP:0002375)2.43086625
74Lower limb muscle weakness (HP:0007340)2.42504615
75Delayed CNS myelination (HP:0002188)2.39154840
76Decreased circulating renin level (HP:0003351)2.38338141
77Morphological abnormality of the pyramidal tract (HP:0002062)2.35350431
78Medial flaring of the eyebrow (HP:0010747)2.35230496
79Delayed gross motor development (HP:0002194)2.35145819
80Abnormality of sodium homeostasis (HP:0010931)2.34389698
81Dehydration (HP:0001944)2.33817644
82Renal tubular dysfunction (HP:0000124)2.33224589
83Absent speech (HP:0001344)2.32668133
84Abnormality of fatty-acid metabolism (HP:0004359)2.32504091
85Hyperglycinemia (HP:0002154)2.31838337
86Confusion (HP:0001289)2.31554052
87Hyponatremia (HP:0002902)2.29809043
88Abnormality of aspartate family amino acid metabolism (HP:0010899)2.29760718
89Epileptic encephalopathy (HP:0200134)2.29302306
90Hand muscle atrophy (HP:0009130)2.29124750
91Rickets (HP:0002748)2.28254032
92Abnormality of renal resorption (HP:0011038)2.26797664
93Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.26519973
94Pheochromocytoma (HP:0002666)2.26497759
95Adrenal overactivity (HP:0002717)2.23865506
96Vaginal atresia (HP:0000148)2.22868152
97Urinary bladder sphincter dysfunction (HP:0002839)2.22703645
98Spastic gait (HP:0002064)2.19133497
99Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.16859155
100Degeneration of the lateral corticospinal tracts (HP:0002314)2.16859155
101Abnormality of calcium-phosphate metabolism (HP:0100530)2.16300912
102Vascular calcification (HP:0004934)2.15503874
103Exotropia (HP:0000577)2.11439808
104Torticollis (HP:0000473)2.11214574
105Rapidly progressive (HP:0003678)2.10966507
106Scanning speech (HP:0002168)2.10430847
107Genital tract atresia (HP:0001827)2.10189444
108Bradykinesia (HP:0002067)2.09497873
109Broad-based gait (HP:0002136)2.09445756
110Insomnia (HP:0100785)2.08714583
111Poor coordination (HP:0002370)2.08119691
112Akinesia (HP:0002304)2.07576434
113Tubular atrophy (HP:0000092)2.06640441
114Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.04291004
115Metabolic acidosis (HP:0001942)2.02176370
116Intention tremor (HP:0002080)2.00917906
117Diminished movement (HP:0002374)2.00182079
118Dicarboxylic aciduria (HP:0003215)1.98675543
119Abnormality of dicarboxylic acid metabolism (HP:0010995)1.98675543
120Metaphyseal irregularity (HP:0003025)1.97301430
121Exercise-induced muscle cramps (HP:0003710)1.95915505
122Vomiting (HP:0002013)1.94180179
123Cutaneous finger syndactyly (HP:0010554)1.94048076
124Metaphyseal dysplasia (HP:0100255)1.92929288
125Abnormal enzyme/coenzyme activity (HP:0012379)1.92870303
126Hyperventilation (HP:0002883)1.92067873
127Hammertoe (HP:0001765)1.91037870
128Abnormality of alkaline phosphatase activity (HP:0004379)1.90930262
129Papillary thyroid carcinoma (HP:0002895)1.90717782
130Aplasia/Hypoplasia of the lens (HP:0008063)1.89804383
131Thin bony cortex (HP:0002753)1.89245764
132Cardiovascular calcification (HP:0011915)1.88221482
133Hyperkalemia (HP:0002153)1.88219512
134Dyskinesia (HP:0100660)1.86451113
135Impaired vibration sensation in the lower limbs (HP:0002166)1.85834453
136Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.85472315
137Aplasia of the phalanges of the hand (HP:0009802)1.84862628
138Aplasia involving bones of the extremities (HP:0009825)1.84862628
139Aplasia involving bones of the upper limbs (HP:0009823)1.84862628
140Apathy (HP:0000741)1.84082525
141Diplopia (HP:0000651)1.83890871
142Abnormality of binocular vision (HP:0011514)1.83890871
143Abnormality of the hip-girdle musculature (HP:0001445)1.83496420
144Abnormality of the musculature of the pelvis (HP:0001469)1.83496420
145Metaphyseal cupping (HP:0003021)1.83018173
146Potter facies (HP:0002009)1.82402495
147Facial shape deformation (HP:0011334)1.82402495
148Abnormal eating behavior (HP:0100738)1.81834232
149Abnormality of the costochondral junction (HP:0000919)1.81417052
150Generalized tonic-clonic seizures (HP:0002069)1.80189493
151Gait ataxia (HP:0002066)1.80065328
152Methylmalonic aciduria (HP:0012120)1.79156644
153Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.79116169
154Specific learning disability (HP:0001328)1.78213947
155Hyperammonemia (HP:0001987)1.77522002
156Tubulointerstitial fibrosis (HP:0005576)1.75730323
157Bicornuate uterus (HP:0000813)1.75685625
158Open mouth (HP:0000194)1.75633240
159Rigidity (HP:0002063)1.75565015
160Hypotension (HP:0002615)1.73059721
161Hemiparesis (HP:0001269)1.72990082
162Dysmetria (HP:0001310)1.72847796
163Papilledema (HP:0001085)1.72547109
164Depression (HP:0000716)1.70364094
165Abnormality of the renal cortex (HP:0011035)1.69816742
166Cortical dysplasia (HP:0002539)1.69762238
167Polyphagia (HP:0002591)1.68707888
168Protruding tongue (HP:0010808)1.68445146
169Gaze-evoked nystagmus (HP:0000640)1.68033581
170Distal upper limb amyotrophy (HP:0007149)1.66291023
171Upper limb amyotrophy (HP:0009129)1.66291023
172Bilateral sensorineural hearing impairment (HP:0008619)1.66157043
173Frequent falls (HP:0002359)1.65680438
174Hypoplasia of the iris (HP:0007676)1.64474082
175Neuronal loss in central nervous system (HP:0002529)1.64404342
176Peripheral hypomyelination (HP:0007182)1.64393769
177Broad foot (HP:0001769)1.64389838
178Tachypnea (HP:0002789)1.64087763
179Abnormality of mucopolysaccharide metabolism (HP:0011020)1.63401599
180Abnormality of polysaccharide metabolism (HP:0011012)1.63401599
181Abnormality of glycosaminoglycan metabolism (HP:0004371)1.63401599
182Paraplegia (HP:0010550)1.63207918
183Spastic tetraplegia (HP:0002510)1.62386233
184Turricephaly (HP:0000262)1.62242133
185Enlarged epiphyses (HP:0010580)1.61330361
186Split foot (HP:0001839)1.60831620
187Abnormal tarsal ossification (HP:0008369)1.60766500
188Sensorimotor neuropathy (HP:0007141)1.60545844
189Elevated alkaline phosphatase (HP:0003155)1.60102015
190Flat cornea (HP:0007720)1.59956524
191Diminished motivation (HP:0000745)1.59467202
192Genetic anticipation (HP:0003743)1.58990257
193Dysostosis multiplex (HP:0000943)1.58700536
194Overriding aorta (HP:0002623)1.58235451
195Urinary glycosaminoglycan excretion (HP:0003541)1.56936199
196Mucopolysacchariduria (HP:0008155)1.56936199

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK38.53131244
2WNK47.98163690
3OXSR17.07317615
4STK393.90428400
5BCR2.15325222
6STK38L2.14283403
7WNK12.11018237
8CSNK1G22.07838251
9LATS22.04897391
10SGK4942.00275471
11SGK2232.00275471
12INSRR1.94131542
13BCKDK1.93514452
14CSNK1G31.67455769
15ERBB31.64893172
16DAPK21.47226432
17EPHB21.39827472
18AKT31.38029304
19SGK21.35782396
20PHKG11.26486866
21PHKG21.26486866
22MAPK151.26098134
23PDK41.18711141
24PDK31.18711141
25SIK21.16042475
26RIPK11.11278186
27SGK31.06967288
28LATS11.05739002
29NTRK31.03747303
30PKN21.03515686
31UHMK11.02964980
32STK381.02894066
33MAP4K21.01480904
34PINK11.00513686
35PDK20.97807863
36EPHA40.97494745
37MAPKAPK50.95851211
38PLK20.94008158
39CAMK2B0.93584724
40MARK20.91303827
41GRK50.89663594
42CAMK1G0.89604294
43SGK10.89424855
44CAMKK10.84817596
45CAMK2A0.83146923
46PDGFRA0.83109268
47RET0.82363811
48ARAF0.81929700
49CASK0.81751417
50CDK140.80455280
51TYRO30.78262363
52CAMK2G0.76543609
53PAK30.75842768
54CDK180.72648498
55MST1R0.71309763
56TNIK0.70995749
57TIE10.70661084
58DYRK1A0.69655903
59CDK150.69601838
60NEK10.67737044
61NEK60.67683703
62BRD40.67114993
63TESK10.66086355
64MAP3K40.61996249
65FER0.61392466
66MAP3K70.61208824
67GSK3A0.61027235
68MAP3K90.60179118
69MAP3K130.59354852
70CDK11A0.58992740
71EPHB10.58895629
72DYRK20.58495116
73PRKD20.58093833
74CAMK1D0.56498925
75OBSCN0.55410297
76PRKAA10.55311076
77IRAK10.55183044
78FGFR40.54794799
79CAMK10.54375839
80PRKAA20.53451037
81PIK3CG0.53013932
82MST40.52524219
83ROCK20.51147196
84IRAK20.50750922
85LIMK10.49813105
86CAMK2D0.49432106
87NTRK10.48666799
88MAPK100.48497770
89TGFBR20.47492088
90EPHA30.45621497
91PTK20.45559624
92PRKACB0.45410825
93FRK0.44164814
94MOS0.43764567
95PRKCE0.42736076
96GRK10.40783997
97PDGFRB0.40080608
98CSNK1D0.40074963
99MAP3K140.39544510
100DAPK10.38348323
101MAP3K50.38347619
102MAP2K70.37838153
103IRAK30.37742235
104RPS6KA30.37712774
105RIPK40.37201947
106PRKCH0.36432005
107GRK70.35953202
108BMPR20.32864923
109DYRK1B0.32423063
110PRKCZ0.31460468
111ADRBK20.31098568
112PRKCG0.30788144
113PDPK10.30156961
114PKN10.30106489
115STK110.29206572
116MET0.28312590
117PRKD30.27373369
118PRKACA0.26804456
119PNCK0.26285994
120PAK60.26079797
121MYLK0.25945704
122MINK10.24994594
123CDK50.23540862
124MAP2K40.23151188
125PRKACG0.23022547
126CAMKK20.22917938
127PRKCA0.22726389
128KSR10.21643709
129MAP3K120.21583984
130MAP3K20.21438990
131PTK60.21323746
132PDK10.21229159
133PRKCI0.21176006
134GRK60.21166822
135MAPK110.20318190
136CSNK1A1L0.18808336
137MARK10.18624420
138IGF1R0.18351528
139PRKCD0.18277056
140HIPK20.17693886
141CSNK1A10.17534291
142ERBB40.16681379
143MAPK130.16187799
144CDC42BPA0.15850458
145CAMK40.15711109
146CSNK1G10.15405086
147YES10.15400138
148PTK2B0.15341444
149NTRK20.15310674
150MAP3K60.14099900

Predicted pathways (KEGG)

RankGene SetZ-score
1Butanoate metabolism_Homo sapiens_hsa006503.99004054
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.96448135
3Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.35681322
4Cyanoamino acid metabolism_Homo sapiens_hsa004603.11032177
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.09343965
6Propanoate metabolism_Homo sapiens_hsa006403.01632994
7Collecting duct acid secretion_Homo sapiens_hsa049662.74948208
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.55824596
9Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.45495295
10Amphetamine addiction_Homo sapiens_hsa050312.40867131
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.38318613
12Peroxisome_Homo sapiens_hsa041462.34024886
13Vitamin digestion and absorption_Homo sapiens_hsa049772.32805671
14Pentose and glucuronate interconversions_Homo sapiens_hsa000402.32035928
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.29596926
16Tryptophan metabolism_Homo sapiens_hsa003802.15234075
17Dopaminergic synapse_Homo sapiens_hsa047282.02012105
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.96956241
19Fatty acid degradation_Homo sapiens_hsa000711.96779639
20Circadian entrainment_Homo sapiens_hsa047131.92656610
21beta-Alanine metabolism_Homo sapiens_hsa004101.86779590
22Sulfur metabolism_Homo sapiens_hsa009201.82714100
23Pyruvate metabolism_Homo sapiens_hsa006201.81930865
24Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.76042040
25Other glycan degradation_Homo sapiens_hsa005111.69693730
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.63093197
27Fatty acid metabolism_Homo sapiens_hsa012121.60951357
28Bile secretion_Homo sapiens_hsa049761.52877223
29Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.51821625
30Lysine degradation_Homo sapiens_hsa003101.49739735
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.48291548
32Long-term potentiation_Homo sapiens_hsa047201.42766456
33Protein digestion and absorption_Homo sapiens_hsa049741.40114448
34Axon guidance_Homo sapiens_hsa043601.37633096
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.36780238
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.36598330
37Mineral absorption_Homo sapiens_hsa049781.30211872
38Arginine and proline metabolism_Homo sapiens_hsa003301.28981738
39Aldosterone synthesis and secretion_Homo sapiens_hsa049251.18324444
40Glutathione metabolism_Homo sapiens_hsa004801.14386136
41Melanogenesis_Homo sapiens_hsa049161.09214425
42Cholinergic synapse_Homo sapiens_hsa047251.08494167
43Carbon metabolism_Homo sapiens_hsa012001.06327288
44Carbohydrate digestion and absorption_Homo sapiens_hsa049731.03560580
45Starch and sucrose metabolism_Homo sapiens_hsa005001.01248056
46Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.01155848
47cAMP signaling pathway_Homo sapiens_hsa040241.00034241
48Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.99163454
49Dilated cardiomyopathy_Homo sapiens_hsa054140.98393808
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97725605
51Oxytocin signaling pathway_Homo sapiens_hsa049210.97570720
52Gap junction_Homo sapiens_hsa045400.96630438
53Hippo signaling pathway_Homo sapiens_hsa043900.96531595
54Fatty acid elongation_Homo sapiens_hsa000620.95284693
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.93421835
56Hedgehog signaling pathway_Homo sapiens_hsa043400.92914194
57Lysosome_Homo sapiens_hsa041420.91928465
58Histidine metabolism_Homo sapiens_hsa003400.86421041
59PPAR signaling pathway_Homo sapiens_hsa033200.85811641
60Long-term depression_Homo sapiens_hsa047300.84823318
61Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.84730664
62Gastric acid secretion_Homo sapiens_hsa049710.84103390
63Glycosaminoglycan degradation_Homo sapiens_hsa005310.82073730
64Synaptic vesicle cycle_Homo sapiens_hsa047210.81818107
65Glycerolipid metabolism_Homo sapiens_hsa005610.81744986
66ECM-receptor interaction_Homo sapiens_hsa045120.81412993
67ErbB signaling pathway_Homo sapiens_hsa040120.79968234
68Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.79279752
69Olfactory transduction_Homo sapiens_hsa047400.78783961
70Phenylalanine metabolism_Homo sapiens_hsa003600.76941891
71AMPK signaling pathway_Homo sapiens_hsa041520.76288182
72Estrogen signaling pathway_Homo sapiens_hsa049150.75288924
73Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74170674
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74007219
75* Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73385022
76GnRH signaling pathway_Homo sapiens_hsa049120.73045802
77Vibrio cholerae infection_Homo sapiens_hsa051100.70799705
78Calcium signaling pathway_Homo sapiens_hsa040200.70593644
79Thyroid hormone synthesis_Homo sapiens_hsa049180.70343876
80Oxidative phosphorylation_Homo sapiens_hsa001900.69385894
81Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.67182491
82Tight junction_Homo sapiens_hsa045300.67101945
83cGMP-PKG signaling pathway_Homo sapiens_hsa040220.66716983
84Sphingolipid metabolism_Homo sapiens_hsa006000.65278479
85Selenocompound metabolism_Homo sapiens_hsa004500.63659421
86Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63627506
87Glucagon signaling pathway_Homo sapiens_hsa049220.61962343
88Ras signaling pathway_Homo sapiens_hsa040140.61654139
89Basal cell carcinoma_Homo sapiens_hsa052170.60871302
90Arginine biosynthesis_Homo sapiens_hsa002200.59786915
91Folate biosynthesis_Homo sapiens_hsa007900.59507887
92Rap1 signaling pathway_Homo sapiens_hsa040150.58435119
93Glioma_Homo sapiens_hsa052140.57651297
94Insulin secretion_Homo sapiens_hsa049110.57313606
95Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.56917113
96Renin-angiotensin system_Homo sapiens_hsa046140.56730876
97Adherens junction_Homo sapiens_hsa045200.56433369
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.56298264
99Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.55894295
100Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55790166
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.55306044
102Fructose and mannose metabolism_Homo sapiens_hsa000510.54911860
103Oocyte meiosis_Homo sapiens_hsa041140.54615102
104Steroid hormone biosynthesis_Homo sapiens_hsa001400.54549395
105Type II diabetes mellitus_Homo sapiens_hsa049300.53934055
106Phototransduction_Homo sapiens_hsa047440.53350810
107Nicotine addiction_Homo sapiens_hsa050330.53245085
108Focal adhesion_Homo sapiens_hsa045100.52415684
109Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.51890259
110Prion diseases_Homo sapiens_hsa050200.51282556
111Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50330278
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50152410
113Insulin signaling pathway_Homo sapiens_hsa049100.49530131
114Wnt signaling pathway_Homo sapiens_hsa043100.49243065
115Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.48750501
116* Metabolic pathways_Homo sapiens_hsa011000.48327996
117Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.47937947
118Fatty acid biosynthesis_Homo sapiens_hsa000610.47319183
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.46887164
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46499897
121Primary bile acid biosynthesis_Homo sapiens_hsa001200.46282537
122Endometrial cancer_Homo sapiens_hsa052130.44555456
123ABC transporters_Homo sapiens_hsa020100.43359399
124Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43126143
125Choline metabolism in cancer_Homo sapiens_hsa052310.42842658
126Inositol phosphate metabolism_Homo sapiens_hsa005620.41626420
127GABAergic synapse_Homo sapiens_hsa047270.41461409
128Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40136402
129Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.39038464
130Biosynthesis of amino acids_Homo sapiens_hsa012300.38817536
131Taste transduction_Homo sapiens_hsa047420.37200702
132Arachidonic acid metabolism_Homo sapiens_hsa005900.37176041
133Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33229891
134Rheumatoid arthritis_Homo sapiens_hsa053230.33042766
135Retinol metabolism_Homo sapiens_hsa008300.31570908
136Nitrogen metabolism_Homo sapiens_hsa009100.31326997
137Morphine addiction_Homo sapiens_hsa050320.28870429
138Salivary secretion_Homo sapiens_hsa049700.26473716
139Cardiac muscle contraction_Homo sapiens_hsa042600.26063667
140Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.24165058
141Pancreatic secretion_Homo sapiens_hsa049720.22956665
142Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.22882309
143Renin secretion_Homo sapiens_hsa049240.21607889
144Steroid biosynthesis_Homo sapiens_hsa001000.20888230
145Chemical carcinogenesis_Homo sapiens_hsa052040.20873812
146Regulation of autophagy_Homo sapiens_hsa041400.19963831
147Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.19727946
148Parkinsons disease_Homo sapiens_hsa050120.17530183
149Ovarian steroidogenesis_Homo sapiens_hsa049130.17151601
150Glutamatergic synapse_Homo sapiens_hsa047240.15529883
151Circadian rhythm_Homo sapiens_hsa047100.15031704
152Cocaine addiction_Homo sapiens_hsa050300.14348425
153Drug metabolism - other enzymes_Homo sapiens_hsa009830.14177618
154Serotonergic synapse_Homo sapiens_hsa047260.13330616

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »