Rank | Gene Set | Z-score |
---|---|---|
1 | cell-substrate junction assembly (GO:0007044) | 3.74287899 |
2 | thyroid hormone generation (GO:0006590) | 3.66602958 |
3 | COPI coating of Golgi vesicle (GO:0048205) | 3.59946015 |
4 | Golgi transport vesicle coating (GO:0048200) | 3.59946015 |
5 | endothelial cell chemotaxis (GO:0035767) | 3.40062413 |
6 | vocalization behavior (GO:0071625) | 3.35928282 |
7 | renal filtration (GO:0097205) | 3.32148526 |
8 | lymphangiogenesis (GO:0001946) | 3.29977700 |
9 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.21745281 |
10 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.14361809 |
11 | surfactant homeostasis (GO:0043129) | 3.14307911 |
12 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.12290284 |
13 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.00863864 |
14 | synaptic vesicle exocytosis (GO:0016079) | 3.00506468 |
15 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.99448598 |
16 | thyroid hormone metabolic process (GO:0042403) | 2.99383463 |
17 | glomerular filtration (GO:0003094) | 2.92784707 |
18 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.89564198 |
19 | axon extension involved in axon guidance (GO:0048846) | 2.88158905 |
20 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.88158905 |
21 | lymph vessel development (GO:0001945) | 2.87040923 |
22 | gap junction assembly (GO:0016264) | 2.86009410 |
23 | chemical homeostasis within a tissue (GO:0048875) | 2.85606170 |
24 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.85000376 |
25 | positive regulation of vesicle fusion (GO:0031340) | 2.84909110 |
26 | basement membrane organization (GO:0071711) | 2.84335104 |
27 | protein retention in ER lumen (GO:0006621) | 2.81854706 |
28 | locomotory exploration behavior (GO:0035641) | 2.80572015 |
29 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 2.77755473 |
30 | synaptic vesicle maturation (GO:0016188) | 2.76662026 |
31 | adherens junction assembly (GO:0034333) | 2.76625277 |
32 | endothelium development (GO:0003158) | 2.76450146 |
33 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.74291629 |
34 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.73837740 |
35 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.73464139 |
36 | cell communication by electrical coupling (GO:0010644) | 2.72698814 |
37 | cell volume homeostasis (GO:0006884) | 2.70336554 |
38 | activation of protein kinase A activity (GO:0034199) | 2.66186601 |
39 | keratinocyte proliferation (GO:0043616) | 2.65817654 |
40 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.64979473 |
41 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.64389610 |
42 | metanephric epithelium development (GO:0072207) | 2.63670801 |
43 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.60226411 |
44 | glutamate secretion (GO:0014047) | 2.59456887 |
45 | atrioventricular valve morphogenesis (GO:0003181) | 2.58756943 |
46 | focal adhesion assembly (GO:0048041) | 2.57700647 |
47 | cell-substrate adherens junction assembly (GO:0007045) | 2.57700647 |
48 | positive regulation of fibroblast migration (GO:0010763) | 2.57455230 |
49 | protein targeting to plasma membrane (GO:0072661) | 2.56960860 |
50 | protein localization to endosome (GO:0036010) | 2.54412231 |
51 | regulation of synapse structural plasticity (GO:0051823) | 2.54300934 |
52 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.52887053 |
53 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.51419415 |
54 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.50987455 |
55 | mating behavior (GO:0007617) | 2.50265808 |
56 | metanephric nephron epithelium development (GO:0072243) | 2.49206042 |
57 | glomerular basement membrane development (GO:0032836) | 2.48399620 |
58 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.47731553 |
59 | positive regulation of synapse maturation (GO:0090129) | 2.47222106 |
60 | regulation of cardioblast differentiation (GO:0051890) | 2.45535608 |
61 | potassium ion homeostasis (GO:0055075) | 2.45240566 |
62 | plasma membrane repair (GO:0001778) | 2.45229875 |
63 | stress fiber assembly (GO:0043149) | 2.44360236 |
64 | phosphate ion transmembrane transport (GO:0035435) | 2.44092357 |
65 | negative regulation of catenin import into nucleus (GO:0035414) | 2.43239301 |
66 | regulation of synaptic vesicle transport (GO:1902803) | 2.42626202 |
67 | proline transport (GO:0015824) | 2.42577761 |
68 | cerebellar granule cell differentiation (GO:0021707) | 2.42556913 |
69 | neuron recognition (GO:0008038) | 2.40765408 |
70 | semaphorin-plexin signaling pathway (GO:0071526) | 2.38053274 |
71 | potassium ion import (GO:0010107) | 2.37648021 |
72 | cellular potassium ion homeostasis (GO:0030007) | 2.37319874 |
73 | positive regulation of axon extension (GO:0045773) | 2.36424996 |
74 | cell communication involved in cardiac conduction (GO:0086065) | 2.35638571 |
75 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.34944708 |
76 | axonal fasciculation (GO:0007413) | 2.34188634 |
77 | regulation of tight junction assembly (GO:2000810) | 2.34139946 |
78 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.33584750 |
79 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.33032265 |
80 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.32145596 |
81 | cell junction assembly (GO:0034329) | 2.31937598 |
82 | Notch signaling involved in heart development (GO:0061314) | 2.31839738 |
83 | detection of calcium ion (GO:0005513) | 2.31748386 |
84 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.31272662 |
85 | positive regulation of muscle hypertrophy (GO:0014742) | 2.30972064 |
86 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 2.30972064 |
87 | epithelial cell-cell adhesion (GO:0090136) | 2.30859510 |
88 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.30253900 |
89 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.29694479 |
90 | layer formation in cerebral cortex (GO:0021819) | 2.28479700 |
91 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 2.28035121 |
92 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.27314250 |
93 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.26697159 |
94 | regulation of vesicle fusion (GO:0031338) | 2.26588080 |
95 | synaptic transmission, glutamatergic (GO:0035249) | 2.26423441 |
96 | cellular sodium ion homeostasis (GO:0006883) | 2.26371776 |
97 | hemidesmosome assembly (GO:0031581) | 2.26270225 |
98 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.25805082 |
99 | protein maturation by protein folding (GO:0022417) | 2.25631400 |
100 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.24762719 |
101 | chondrocyte proliferation (GO:0035988) | 2.24363528 |
102 | adhesion of symbiont to host cell (GO:0044650) | 2.24302497 |
103 | virion attachment to host cell (GO:0019062) | 2.24302497 |
104 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.24298164 |
105 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.24116998 |
106 | cochlea development (GO:0090102) | 2.23707468 |
107 | regulation of glucocorticoid metabolic process (GO:0031943) | 2.23185063 |
108 | sodium ion export (GO:0071436) | 2.23067453 |
109 | wound healing, spreading of epidermal cells (GO:0035313) | 2.22880378 |
110 | cell adhesion mediated by integrin (GO:0033627) | 2.21610155 |
111 | regulation of glomerular filtration (GO:0003093) | 2.21602906 |
112 | innervation (GO:0060384) | 2.21581508 |
113 | positive regulation of odontogenesis (GO:0042482) | 2.21411142 |
114 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 2.21239870 |
115 | metanephric nephron tubule development (GO:0072234) | 2.21168236 |
116 | metanephric tubule development (GO:0072170) | 2.21168236 |
117 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.20753214 |
118 | adherens junction organization (GO:0034332) | 2.20537692 |
119 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.20155430 |
120 | regulation of steroid hormone biosynthetic process (GO:0090030) | 2.19540896 |
121 | sodium ion homeostasis (GO:0055078) | 2.19478476 |
122 | exploration behavior (GO:0035640) | 2.18737294 |
123 | artery smooth muscle contraction (GO:0014824) | 2.18231797 |
124 | blood vessel endothelial cell migration (GO:0043534) | 2.17808703 |
125 | tonic smooth muscle contraction (GO:0014820) | 2.17597570 |
126 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.15962287 |
127 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 2.14578070 |
128 | axon extension (GO:0048675) | 2.13798879 |
129 | neuronal ion channel clustering (GO:0045161) | 2.13308600 |
130 | negative regulation of hormone metabolic process (GO:0032351) | 2.12607588 |
131 | negative regulation of hormone biosynthetic process (GO:0032353) | 2.12607588 |
132 | dendritic spine organization (GO:0097061) | 2.12468488 |
133 | protein localization to synapse (GO:0035418) | 2.11978180 |
134 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.11897806 |
135 | long term synaptic depression (GO:0060292) | 2.11864685 |
136 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.11511546 |
137 | induction of positive chemotaxis (GO:0050930) | 2.11205130 |
138 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.10980875 |
139 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.10528784 |
140 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.10107563 |
141 | cell junction organization (GO:0034330) | 2.09396107 |
142 | cAMP biosynthetic process (GO:0006171) | 2.09274089 |
143 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.09101564 |
144 | desmosome organization (GO:0002934) | 2.08870293 |
145 | 4-hydroxyproline metabolic process (GO:0019471) | 2.07452110 |
146 | postsynaptic membrane organization (GO:0001941) | 2.07204958 |
147 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 2.07122531 |
148 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 2.07122531 |
149 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.06534441 |
150 | cellular response to vitamin (GO:0071295) | 2.06384566 |
151 | toxin metabolic process (GO:0009404) | 2.06363918 |
152 | apoptotic cell clearance (GO:0043277) | 2.05192212 |
153 | cerebellar Purkinje cell layer development (GO:0021680) | 2.04937262 |
154 | regulation of synaptic plasticity (GO:0048167) | 2.04811379 |
155 | neuromuscular junction development (GO:0007528) | 2.04756917 |
156 | adhesion of symbiont to host (GO:0044406) | 2.04747549 |
157 | myelination in peripheral nervous system (GO:0022011) | 2.04625027 |
158 | peripheral nervous system axon ensheathment (GO:0032292) | 2.04625027 |
159 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 2.03658134 |
160 | amino acid import (GO:0043090) | 2.03537727 |
161 | thyroid gland development (GO:0030878) | 2.02080214 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.58234970 |
2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.33237057 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.86731391 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.69947081 |
5 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.55647281 |
6 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.50265583 |
7 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.44208009 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.44208009 |
9 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.43208103 |
10 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.41665476 |
11 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.34927632 |
12 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.28384943 |
13 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.25335585 |
14 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.20393259 |
15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.20212354 |
16 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.16947676 |
17 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.05833067 |
18 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.98726955 |
19 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.94101729 |
20 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.87548336 |
21 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.86360675 |
22 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.81855736 |
23 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.80314811 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.73615593 |
25 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.69909860 |
26 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.63344422 |
27 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.60547502 |
28 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.59139092 |
29 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.57755377 |
30 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.57448972 |
31 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.51851469 |
32 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.49651457 |
33 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.47646507 |
34 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.46000140 |
35 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.44431802 |
36 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.42507121 |
37 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.41576215 |
38 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.40885643 |
39 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.40135672 |
40 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.38969239 |
41 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.36661464 |
42 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.34998268 |
43 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.34874980 |
44 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.34249796 |
45 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.34249796 |
46 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.34022634 |
47 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.32863700 |
48 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.32401418 |
49 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.32338516 |
50 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.32319753 |
51 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.32056534 |
52 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.32029225 |
53 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.31871164 |
54 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.28187753 |
55 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.28187753 |
56 | CJUN_26792858_Chip-Seq_BT549_Human | 1.25929584 |
57 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.24126197 |
58 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.23301147 |
59 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.22122276 |
60 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.21735597 |
61 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.20755911 |
62 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.19779101 |
63 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.19748186 |
64 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.18298559 |
65 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.18070590 |
66 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.17472226 |
67 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.16460490 |
68 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.15671625 |
69 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.15463873 |
70 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.15245268 |
71 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.14607452 |
72 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.13648476 |
73 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.13620011 |
74 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.12811945 |
75 | RXR_22108803_ChIP-Seq_LS180_Human | 1.12693662 |
76 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.12474796 |
77 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.12363638 |
78 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.11198571 |
79 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.10233158 |
80 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.08695498 |
81 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.08299335 |
82 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.08299335 |
83 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.06555921 |
84 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.06420153 |
85 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.05938452 |
86 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.05934456 |
87 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.05736614 |
88 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.05374801 |
89 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.04382442 |
90 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.04250578 |
91 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.03463599 |
92 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.02577315 |
93 | KDM2B_26808549_Chip-Seq_K562_Human | 1.02436275 |
94 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.02319161 |
95 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.02170947 |
96 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.02046937 |
97 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.01709834 |
98 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.00963133 |
99 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.00103236 |
100 | GATA1_22025678_ChIP-Seq_K562_Human | 0.99990823 |
101 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.99319266 |
102 | AR_25329375_ChIP-Seq_VCAP_Human | 0.98813998 |
103 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.98804577 |
104 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.98507952 |
105 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.98477770 |
106 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98334534 |
107 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.98188452 |
108 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.96630096 |
109 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.95659992 |
110 | TP53_16413492_ChIP-PET_HCT116_Human | 0.95147634 |
111 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.94556792 |
112 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.93790221 |
113 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.92684782 |
114 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.92579536 |
115 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.92559934 |
116 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.92187404 |
117 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.92058698 |
118 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.91541446 |
119 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.91140117 |
120 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.90620134 |
121 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.90019098 |
122 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.89918295 |
123 | P300_19829295_ChIP-Seq_ESCs_Human | 0.89700906 |
124 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.89657869 |
125 | AR_19668381_ChIP-Seq_PC3_Human | 0.89558031 |
126 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.89517415 |
127 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.89456691 |
128 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.89381730 |
129 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.88469538 |
130 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.88384495 |
131 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.88333159 |
132 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.88064465 |
133 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.86255374 |
134 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.85729565 |
135 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.82983982 |
136 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.82981480 |
137 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.82593608 |
138 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.82372301 |
139 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.81526651 |
140 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.81261096 |
141 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.80468840 |
142 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.80327562 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 3.63212498 |
2 | MP0000579_abnormal_nail_morphology | 3.53791369 |
3 | MP0000013_abnormal_adipose_tissue | 3.35934052 |
4 | MP0010368_abnormal_lymphatic_system | 3.11659763 |
5 | MP0009780_abnormal_chondrocyte_physiolo | 3.11613562 |
6 | MP0004272_abnormal_basement_membrane | 2.62370641 |
7 | MP0000537_abnormal_urethra_morphology | 2.56537934 |
8 | MP0008438_abnormal_cutaneous_collagen | 2.48947082 |
9 | MP0005409_darkened_coat_color | 2.48116144 |
10 | MP0000566_synostosis | 2.47792988 |
11 | MP0001879_abnormal_lymphatic_vessel | 2.44264848 |
12 | MP0001958_emphysema | 2.41475105 |
13 | MP0002837_dystrophic_cardiac_calcinosis | 2.31085978 |
14 | MP0003635_abnormal_synaptic_transmissio | 2.17606327 |
15 | MP0005275_abnormal_skin_tensile | 2.17058738 |
16 | MP0003880_abnormal_central_pattern | 2.15667356 |
17 | MP0002909_abnormal_adrenal_gland | 2.10317776 |
18 | MP0000762_abnormal_tongue_morphology | 2.08578247 |
19 | MP0002735_abnormal_chemical_nociception | 2.01162766 |
20 | MP0005623_abnormal_meninges_morphology | 1.98026666 |
21 | MP0006054_spinal_hemorrhage | 1.96363323 |
22 | MP0001968_abnormal_touch/_nociception | 1.93284470 |
23 | MP0002295_abnormal_pulmonary_circulatio | 1.90767040 |
24 | MP0004858_abnormal_nervous_system | 1.88171273 |
25 | MP0003279_aneurysm | 1.87655398 |
26 | MP0002736_abnormal_nociception_after | 1.86145081 |
27 | MP0010678_abnormal_skin_adnexa | 1.83753765 |
28 | MP0002877_abnormal_melanocyte_morpholog | 1.83713196 |
29 | MP0004270_analgesia | 1.82101848 |
30 | MP0008004_abnormal_stomach_pH | 1.80484319 |
31 | MP0010386_abnormal_urinary_bladder | 1.77392976 |
32 | MP0003705_abnormal_hypodermis_morpholog | 1.76346443 |
33 | MP0002063_abnormal_learning/memory/cond | 1.65443028 |
34 | MP0002254_reproductive_system_inflammat | 1.61213196 |
35 | MP0005167_abnormal_blood-brain_barrier | 1.61184081 |
36 | MP0003329_amyloid_beta_deposits | 1.60784538 |
37 | MP0009745_abnormal_behavioral_response | 1.58719881 |
38 | MP0010030_abnormal_orbit_morphology | 1.55848997 |
39 | MP0000383_abnormal_hair_follicle | 1.52275121 |
40 | MP0000462_abnormal_digestive_system | 1.49831182 |
41 | MP0009384_cardiac_valve_regurgitation | 1.49011538 |
42 | MP0005503_abnormal_tendon_morphology | 1.47561742 |
43 | MP0000467_abnormal_esophagus_morphology | 1.46712768 |
44 | MP0003283_abnormal_digestive_organ | 1.46545677 |
45 | MP0004782_abnormal_surfactant_physiolog | 1.43447587 |
46 | MP0004215_abnormal_myocardial_fiber | 1.42455095 |
47 | MP0003941_abnormal_skin_development | 1.39144944 |
48 | MP0002796_impaired_skin_barrier | 1.37534521 |
49 | MP0002734_abnormal_mechanical_nocicepti | 1.37042997 |
50 | MP0003566_abnormal_cell_adhesion | 1.36960895 |
51 | MP0000681_abnormal_thyroid_gland | 1.36862024 |
52 | MP0002733_abnormal_thermal_nociception | 1.35919336 |
53 | MP0005595_abnormal_vascular_smooth | 1.35723899 |
54 | MP0003879_abnormal_hair_cell | 1.34973732 |
55 | MP0004043_abnormal_pH_regulation | 1.34666169 |
56 | MP0001440_abnormal_grooming_behavior | 1.33169468 |
57 | MP0001849_ear_inflammation | 1.30612130 |
58 | MP0002876_abnormal_thyroid_physiology | 1.30024762 |
59 | MP0002064_seizures | 1.28542414 |
60 | MP0001501_abnormal_sleep_pattern | 1.25660250 |
61 | MP0002572_abnormal_emotion/affect_behav | 1.25141503 |
62 | MP0002896_abnormal_bone_mineralization | 1.24020335 |
63 | MP0000003_abnormal_adipose_tissue | 1.23034774 |
64 | MP0005257_abnormal_intraocular_pressure | 1.21710789 |
65 | MP0000751_myopathy | 1.21483557 |
66 | MP0004084_abnormal_cardiac_muscle | 1.21165279 |
67 | MP0010234_abnormal_vibrissa_follicle | 1.20566205 |
68 | MP0001765_abnormal_ion_homeostasis | 1.17454258 |
69 | MP0003091_abnormal_cell_migration | 1.16423420 |
70 | MP0003045_fibrosis | 1.16189964 |
71 | MP0002060_abnormal_skin_morphology | 1.13728323 |
72 | MP0004085_abnormal_heartbeat | 1.13601954 |
73 | MP0001299_abnormal_eye_distance/ | 1.13523437 |
74 | MP0001970_abnormal_pain_threshold | 1.12965352 |
75 | MP0005330_cardiomyopathy | 1.11639463 |
76 | MP0003453_abnormal_keratinocyte_physiol | 1.10846876 |
77 | MP0005423_abnormal_somatic_nervous | 1.10395930 |
78 | MP0006138_congestive_heart_failure | 1.10096353 |
79 | MP0009053_abnormal_anal_canal | 1.09962103 |
80 | MP0001348_abnormal_lacrimal_gland | 1.08480346 |
81 | MP0003315_abnormal_perineum_morphology | 1.07301075 |
82 | MP0004885_abnormal_endolymph | 1.04960829 |
83 | MP0002098_abnormal_vibrissa_morphology | 1.04233524 |
84 | MP0004484_altered_response_of | 1.03827400 |
85 | MP0004036_abnormal_muscle_relaxation | 1.02578266 |
86 | MP0001177_atelectasis | 1.02442910 |
87 | MP0002272_abnormal_nervous_system | 1.02338607 |
88 | MP0003828_pulmonary_edema | 1.02075921 |
89 | MP0000678_abnormal_parathyroid_gland | 0.96263113 |
90 | MP0005187_abnormal_penis_morphology | 0.95741994 |
91 | MP0000230_abnormal_systemic_arterial | 0.95634676 |
92 | MP0001542_abnormal_bone_strength | 0.95016763 |
93 | MP0003634_abnormal_glial_cell | 0.94144381 |
94 | MP0008961_abnormal_basal_metabolism | 0.93806766 |
95 | MP0000534_abnormal_ureter_morphology | 0.93059353 |
96 | MP0005023_abnormal_wound_healing | 0.92701099 |
97 | MP0003011_delayed_dark_adaptation | 0.91973855 |
98 | MP0002972_abnormal_cardiac_muscle | 0.91111678 |
99 | MP0010771_integument_phenotype | 0.89061334 |
100 | MP0002184_abnormal_innervation | 0.88301902 |
101 | MP0003183_abnormal_peptide_metabolism | 0.87334037 |
102 | MP0005165_increased_susceptibility_to | 0.86855081 |
103 | MP0005620_abnormal_muscle_contractility | 0.86397504 |
104 | MP0002234_abnormal_pharynx_morphology | 0.83370720 |
105 | MP0000750_abnormal_muscle_regeneration | 0.83295379 |
106 | MP0002067_abnormal_sensory_capabilities | 0.83234656 |
107 | MP0005501_abnormal_skin_physiology | 0.82585860 |
108 | MP0004130_abnormal_muscle_cell | 0.82394191 |
109 | MP0004233_abnormal_muscle_weight | 0.82021300 |
110 | MP0005508_abnormal_skeleton_morphology | 0.81633520 |
111 | MP0000538_abnormal_urinary_bladder | 0.80293300 |
112 | MP0005164_abnormal_response_to | 0.80188953 |
113 | MP0001944_abnormal_pancreas_morphology | 0.79978005 |
114 | MP0003300_gastrointestinal_ulcer | 0.79929147 |
115 | MP0003633_abnormal_nervous_system | 0.78399881 |
116 | MP0003075_altered_response_to | 0.76656288 |
117 | MP0002138_abnormal_hepatobiliary_system | 0.75774254 |
118 | MP0003942_abnormal_urinary_system | 0.75688757 |
119 | MP0002133_abnormal_respiratory_system | 0.75661876 |
120 | MP0005388_respiratory_system_phenotype | 0.75661876 |
121 | MP0001270_distended_abdomen | 0.75543871 |
122 | MP0009046_muscle_twitch | 0.75238666 |
123 | MP0002557_abnormal_social/conspecific_i | 0.74655275 |
124 | MP0006276_abnormal_autonomic_nervous | 0.74649922 |
125 | MP0003122_maternal_imprinting | 0.73880416 |
126 | MP0000767_abnormal_smooth_muscle | 0.73592458 |
127 | MP0000778_abnormal_nervous_system | 0.72554167 |
128 | MP0004811_abnormal_neuron_physiology | 0.71945669 |
129 | MP0001502_abnormal_circadian_rhythm | 0.71911210 |
130 | MP0002089_abnormal_postnatal_growth/wei | 0.71687293 |
131 | MP0010630_abnormal_cardiac_muscle | 0.71657379 |
132 | MP0002822_catalepsy | 0.71458390 |
133 | MP0001664_abnormal_digestion | 0.71354080 |
134 | MP0009840_abnormal_foam_cell | 0.70138697 |
135 | MP0008569_lethality_at_weaning | 0.70096976 |
136 | MP0000733_abnormal_muscle_development | 0.69373602 |
137 | MP0009379_abnormal_foot_pigmentation | 0.69104872 |
138 | MP0001661_extended_life_span | 0.68484770 |
139 | MP0004087_abnormal_muscle_fiber | 0.68332141 |
140 | MP0005197_abnormal_uvea_morphology | 0.64117038 |
141 | MP0001216_abnormal_epidermal_layer | 0.63886878 |
142 | MP0000920_abnormal_myelination | 0.63797090 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperactive renin-angiotensin system (HP:0000841) | 4.04196490 |
2 | Focal motor seizures (HP:0011153) | 3.93424930 |
3 | Protrusio acetabuli (HP:0003179) | 3.87144905 |
4 | Milia (HP:0001056) | 3.86974926 |
5 | Premature rupture of membranes (HP:0001788) | 3.86900016 |
6 | Fragile nails (HP:0001808) | 3.62869182 |
7 | Pili torti (HP:0003777) | 3.53863886 |
8 | Atrophic scars (HP:0001075) | 3.42436316 |
9 | Plantar hyperkeratosis (HP:0007556) | 3.17666949 |
10 | Visual hallucinations (HP:0002367) | 3.03975048 |
11 | Broad metatarsal (HP:0001783) | 2.96717428 |
12 | Cerebral aneurysm (HP:0004944) | 2.94281203 |
13 | Aortic aneurysm (HP:0004942) | 2.81673862 |
14 | Abnormality of nail color (HP:0100643) | 2.76344279 |
15 | Decreased circulating renin level (HP:0003351) | 2.76217553 |
16 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.73743330 |
17 | Right ventricular cardiomyopathy (HP:0011663) | 2.70857675 |
18 | Atonic seizures (HP:0010819) | 2.69148437 |
19 | Myokymia (HP:0002411) | 2.68087112 |
20 | Shallow orbits (HP:0000586) | 2.61657386 |
21 | Aortic dissection (HP:0002647) | 2.56077348 |
22 | Vascular tortuosity (HP:0004948) | 2.55376346 |
23 | Hypercortisolism (HP:0001578) | 2.55332389 |
24 | Focal seizures (HP:0007359) | 2.55103323 |
25 | Thick nail (HP:0001805) | 2.52652424 |
26 | Congenital glaucoma (HP:0001087) | 2.45638247 |
27 | Adrenal overactivity (HP:0002717) | 2.45583784 |
28 | Abnormality of dentin (HP:0010299) | 2.45400567 |
29 | Alopecia of scalp (HP:0002293) | 2.43029919 |
30 | Short nail (HP:0001799) | 2.41277864 |
31 | Abnormal hair laboratory examination (HP:0003328) | 2.40624055 |
32 | Nail dystrophy (HP:0008404) | 2.39654205 |
33 | Dysmetric saccades (HP:0000641) | 2.37963261 |
34 | Hypokalemic alkalosis (HP:0001949) | 2.36697849 |
35 | Arterial tortuosity (HP:0005116) | 2.36331535 |
36 | Hyperaldosteronism (HP:0000859) | 2.35835178 |
37 | Abnormality of renin-angiotensin system (HP:0000847) | 2.32486727 |
38 | Ridged nail (HP:0001807) | 2.31830442 |
39 | Increased circulating renin level (HP:0000848) | 2.31812772 |
40 | Hypotrichosis (HP:0001006) | 2.30750602 |
41 | Spinal rigidity (HP:0003306) | 2.26323815 |
42 | Goiter (HP:0000853) | 2.25833552 |
43 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.23067779 |
44 | Cerebral inclusion bodies (HP:0100314) | 2.19721878 |
45 | Distal upper limb amyotrophy (HP:0007149) | 2.18122080 |
46 | Upper limb amyotrophy (HP:0009129) | 2.18122080 |
47 | Cervical subluxation (HP:0003308) | 2.16877235 |
48 | Overgrowth (HP:0001548) | 2.16689242 |
49 | Increased variability in muscle fiber diameter (HP:0003557) | 2.16380606 |
50 | Pterygium (HP:0001059) | 2.16201633 |
51 | Fragile skin (HP:0001030) | 2.14234307 |
52 | Aplasia involving bones of the extremities (HP:0009825) | 2.13863040 |
53 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.13863040 |
54 | Aplasia of the phalanges of the hand (HP:0009802) | 2.13863040 |
55 | Hypoplasia of dental enamel (HP:0006297) | 2.13746360 |
56 | Dilatation of the ascending aorta (HP:0005111) | 2.12954393 |
57 | Buphthalmos (HP:0000557) | 2.11491842 |
58 | Gout (HP:0001997) | 2.10208377 |
59 | Bronchomalacia (HP:0002780) | 2.09473903 |
60 | Nonimmune hydrops fetalis (HP:0001790) | 2.09235973 |
61 | Difficulty climbing stairs (HP:0003551) | 2.08048089 |
62 | Bundle branch block (HP:0011710) | 2.07707166 |
63 | Onycholysis (HP:0001806) | 2.05989604 |
64 | Atrioventricular block (HP:0001678) | 2.05671512 |
65 | Bradycardia (HP:0001662) | 2.05558777 |
66 | Aneurysm (HP:0002617) | 2.05253015 |
67 | Palmoplantar hyperkeratosis (HP:0000972) | 2.04597323 |
68 | Ulnar bowing (HP:0003031) | 2.03883185 |
69 | Neurofibrillary tangles (HP:0002185) | 2.03862582 |
70 | Vertebral arch anomaly (HP:0008438) | 2.02349365 |
71 | Hyporeflexia of lower limbs (HP:0002600) | 2.02051089 |
72 | Distal lower limb muscle weakness (HP:0009053) | 1.99465351 |
73 | Hand muscle atrophy (HP:0009130) | 1.98886644 |
74 | Epileptic encephalopathy (HP:0200134) | 1.98517054 |
75 | Short hallux (HP:0010109) | 1.98227779 |
76 | Rapidly progressive (HP:0003678) | 1.97732823 |
77 | Action tremor (HP:0002345) | 1.97479908 |
78 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.97272592 |
79 | Long toe (HP:0010511) | 1.97185074 |
80 | Natal tooth (HP:0000695) | 1.95977055 |
81 | Abnormality of the lower motor neuron (HP:0002366) | 1.95410121 |
82 | Abnormality of the dental root (HP:0006486) | 1.94877411 |
83 | Taurodontia (HP:0000679) | 1.94877411 |
84 | Abnormality of permanent molar morphology (HP:0011071) | 1.94877411 |
85 | Amblyopia (HP:0000646) | 1.94421158 |
86 | Renal salt wasting (HP:0000127) | 1.92106670 |
87 | Bladder diverticulum (HP:0000015) | 1.90509211 |
88 | Spinal cord compression (HP:0002176) | 1.89921039 |
89 | Abnormal atrioventricular conduction (HP:0005150) | 1.89845600 |
90 | Hypoplasia of the iris (HP:0007676) | 1.88543422 |
91 | Follicular hyperkeratosis (HP:0007502) | 1.88171114 |
92 | Abnormality of chloride homeostasis (HP:0011422) | 1.87739625 |
93 | Advanced eruption of teeth (HP:0006288) | 1.87446928 |
94 | Abnormality of molar (HP:0011077) | 1.87120311 |
95 | Abnormality of molar morphology (HP:0011070) | 1.87120311 |
96 | Dry hair (HP:0011359) | 1.87051975 |
97 | Hyperkalemia (HP:0002153) | 1.86990195 |
98 | Hyperparathyroidism (HP:0000843) | 1.85375729 |
99 | Absence seizures (HP:0002121) | 1.83747208 |
100 | Broad face (HP:0000283) | 1.83733220 |
101 | Supranuclear gaze palsy (HP:0000605) | 1.83025722 |
102 | Neonatal death (HP:0003811) | 1.82965888 |
103 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.81324044 |
104 | Hypoplastic left heart (HP:0004383) | 1.80736830 |
105 | Abnormality of the nasal mucosa (HP:0000433) | 1.80640660 |
106 | Hemiplegia (HP:0002301) | 1.80185909 |
107 | Polycythemia (HP:0001901) | 1.80097358 |
108 | Palmar hyperkeratosis (HP:0010765) | 1.79792376 |
109 | Hypoventilation (HP:0002791) | 1.79151189 |
110 | Hypokalemia (HP:0002900) | 1.78727700 |
111 | Interstitial pulmonary disease (HP:0006530) | 1.78126609 |
112 | Ventricular tachycardia (HP:0004756) | 1.77941575 |
113 | Obstructive sleep apnea (HP:0002870) | 1.77908368 |
114 | Diaphragmatic weakness (HP:0009113) | 1.76989920 |
115 | Hyperacusis (HP:0010780) | 1.76266300 |
116 | Thin bony cortex (HP:0002753) | 1.75613261 |
117 | Vertebral compression fractures (HP:0002953) | 1.75279200 |
118 | Abnormality of renal excretion (HP:0011036) | 1.74098957 |
119 | Hyperextensible skin (HP:0000974) | 1.73741026 |
120 | Abnormality of the dental pulp (HP:0006479) | 1.73038294 |
121 | Increased connective tissue (HP:0009025) | 1.72987678 |
122 | Osteopenia (HP:0000938) | 1.72275143 |
123 | Heart block (HP:0012722) | 1.72039506 |
124 | Scanning speech (HP:0002168) | 1.71839211 |
125 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.71099337 |
126 | Facial shape deformation (HP:0011334) | 1.70263750 |
127 | Potter facies (HP:0002009) | 1.70263750 |
128 | Insomnia (HP:0100785) | 1.69935829 |
129 | Hydroureter (HP:0000072) | 1.69380403 |
130 | Atrial fibrillation (HP:0005110) | 1.67595109 |
131 | Thyroid-stimulating hormone excess (HP:0002925) | 1.67274684 |
132 | Abnormal urine output (HP:0012590) | 1.66788482 |
133 | Generalized tonic-clonic seizures (HP:0002069) | 1.66671417 |
134 | Absent hand (HP:0004050) | 1.66142134 |
135 | Supraventricular arrhythmia (HP:0005115) | 1.65979021 |
136 | Growth hormone excess (HP:0000845) | 1.65841174 |
137 | Neonatal short-limb short stature (HP:0008921) | 1.65486058 |
138 | Myotonia (HP:0002486) | 1.64233834 |
139 | Deep venous thrombosis (HP:0002625) | 1.64085309 |
140 | Abnormality of potassium homeostasis (HP:0011042) | 1.63795849 |
141 | Hoarse voice (HP:0001609) | 1.62655587 |
142 | Turricephaly (HP:0000262) | 1.62425226 |
143 | Wormian bones (HP:0002645) | 1.62394219 |
144 | Joint stiffness (HP:0001387) | 1.62073909 |
145 | Type 1 muscle fiber predominance (HP:0003803) | 1.61572284 |
146 | Ketoacidosis (HP:0001993) | 1.61527750 |
147 | Vascular calcification (HP:0004934) | 1.61143495 |
148 | Hypotension (HP:0002615) | 1.61036241 |
149 | Stridor (HP:0010307) | 1.60864726 |
150 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.60562323 |
151 | Osteolytic defects of the hand bones (HP:0009699) | 1.60562323 |
152 | Absent eyelashes (HP:0000561) | 1.60087837 |
153 | Soft skin (HP:0000977) | 1.59863047 |
154 | Truncal ataxia (HP:0002078) | 1.59644989 |
155 | Syncope (HP:0001279) | 1.58629619 |
156 | Distal lower limb amyotrophy (HP:0008944) | 1.58531696 |
157 | Dysmetria (HP:0001310) | 1.58330085 |
158 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.58283489 |
159 | Mucopolysacchariduria (HP:0008155) | 1.58283489 |
160 | Diplopia (HP:0000651) | 1.58157234 |
161 | Abnormality of binocular vision (HP:0011514) | 1.58157234 |
162 | Laryngomalacia (HP:0001601) | 1.57339755 |
163 | Muscle fiber splitting (HP:0003555) | 1.56512449 |
164 | Peritonitis (HP:0002586) | 1.56470959 |
165 | Depression (HP:0000716) | 1.56329192 |
166 | Sudden death (HP:0001699) | 1.55444785 |
167 | Abnormality of the salivary glands (HP:0010286) | 1.52570229 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TIE1 | 3.57712452 |
2 | NTRK3 | 3.49411584 |
3 | EPHA4 | 3.43015354 |
4 | KDR | 3.14008290 |
5 | MST1R | 2.79788448 |
6 | FER | 2.71263926 |
7 | ERN1 | 2.36967398 |
8 | PTK2B | 2.15609060 |
9 | NTRK1 | 2.06085178 |
10 | DAPK2 | 1.94189598 |
11 | PRKD3 | 1.84261445 |
12 | LATS2 | 1.82737236 |
13 | MAP3K9 | 1.76659864 |
14 | TRIB3 | 1.70932247 |
15 | KSR2 | 1.61352236 |
16 | MINK1 | 1.61131487 |
17 | MYLK | 1.59945976 |
18 | SIK1 | 1.57253763 |
19 | DDR2 | 1.51542858 |
20 | MAP3K2 | 1.51358450 |
21 | MAP3K4 | 1.49258092 |
22 | PTK2 | 1.47250799 |
23 | PDGFRA | 1.44726093 |
24 | TESK1 | 1.44317677 |
25 | PAK4 | 1.42996272 |
26 | INSRR | 1.42126425 |
27 | EPHB2 | 1.39645443 |
28 | PAK3 | 1.31580965 |
29 | EEF2K | 1.29514488 |
30 | ARAF | 1.28127223 |
31 | GRK5 | 1.23695571 |
32 | WNK4 | 1.23503256 |
33 | TSSK6 | 1.21846461 |
34 | TGFBR2 | 1.20492485 |
35 | OXSR1 | 1.16885086 |
36 | MAP2K1 | 1.16524939 |
37 | PLK2 | 1.14559876 |
38 | PIM2 | 1.13476471 |
39 | LMTK2 | 1.13145534 |
40 | CAMKK1 | 1.12878428 |
41 | ROCK2 | 1.12106300 |
42 | PAK6 | 1.11957925 |
43 | FRK | 1.11468655 |
44 | ILK | 1.09321847 |
45 | CAMKK2 | 1.08503134 |
46 | CASK | 1.08225336 |
47 | RET | 1.07877895 |
48 | MAP2K7 | 1.05284021 |
49 | CDK12 | 1.04477399 |
50 | LATS1 | 1.02689222 |
51 | PRPF4B | 1.02527657 |
52 | LIMK1 | 1.01822473 |
53 | ICK | 1.01702637 |
54 | SMG1 | 0.98865965 |
55 | MAPK15 | 0.98803165 |
56 | AKT3 | 0.94802982 |
57 | CDK5 | 0.90899356 |
58 | MAP3K1 | 0.89966022 |
59 | BRAF | 0.88184568 |
60 | CDC42BPA | 0.87685701 |
61 | DAPK1 | 0.87339748 |
62 | TTN | 0.85754642 |
63 | STK38 | 0.84530520 |
64 | MAP2K4 | 0.83611956 |
65 | KSR1 | 0.83095082 |
66 | ERBB3 | 0.83084703 |
67 | RAF1 | 0.80629754 |
68 | RIPK1 | 0.80598717 |
69 | EPHA2 | 0.79142619 |
70 | CAMK2A | 0.78463213 |
71 | FGFR2 | 0.77106456 |
72 | RIPK4 | 0.76865597 |
73 | EPHA3 | 0.75711830 |
74 | CAMK2G | 0.74618731 |
75 | MAPKAPK3 | 0.74110474 |
76 | PRKCE | 0.73913053 |
77 | MAP3K3 | 0.72995194 |
78 | MAP3K12 | 0.70858142 |
79 | PTK6 | 0.70317333 |
80 | MTOR | 0.70028154 |
81 | PRKCH | 0.69359162 |
82 | STK39 | 0.69203509 |
83 | DAPK3 | 0.68356903 |
84 | CAMK2B | 0.67417475 |
85 | WNK3 | 0.67225742 |
86 | STK38L | 0.66665395 |
87 | ERBB4 | 0.66054137 |
88 | AKT2 | 0.64340471 |
89 | TAOK1 | 0.64168706 |
90 | PDK2 | 0.64083448 |
91 | DMPK | 0.62452979 |
92 | NME1 | 0.61612402 |
93 | MAP3K13 | 0.58299454 |
94 | SGK3 | 0.57125005 |
95 | CDK14 | 0.56469313 |
96 | ROCK1 | 0.56320788 |
97 | PRKCG | 0.56000284 |
98 | MUSK | 0.55659506 |
99 | PHKG1 | 0.52357562 |
100 | PHKG2 | 0.52357562 |
101 | PDGFRB | 0.50903333 |
102 | SCYL2 | 0.50215196 |
103 | SGK494 | 0.49544033 |
104 | SGK223 | 0.49544033 |
105 | PDPK1 | 0.49248733 |
106 | CAMK2D | 0.47937895 |
107 | MOS | 0.47607659 |
108 | PKN2 | 0.47043665 |
109 | PRKD1 | 0.46178061 |
110 | EPHB1 | 0.45967013 |
111 | UHMK1 | 0.45628224 |
112 | GRK1 | 0.45269051 |
113 | MAPK7 | 0.45127685 |
114 | CDK18 | 0.45017912 |
115 | FES | 0.44961793 |
116 | MET | 0.44539030 |
117 | MARK1 | 0.44298799 |
118 | SRC | 0.43286867 |
119 | NTRK2 | 0.43124304 |
120 | CDK15 | 0.42646488 |
121 | RPS6KA2 | 0.42535788 |
122 | PRKG2 | 0.41817105 |
123 | MARK2 | 0.40724826 |
124 | MAPK12 | 0.40072436 |
125 | PAK2 | 0.38230770 |
126 | MAPK10 | 0.37611035 |
127 | PRKD2 | 0.36493367 |
128 | SGK2 | 0.36175561 |
129 | ABL2 | 0.35342130 |
130 | CAMK1G | 0.34633963 |
131 | PRKCI | 0.34018696 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.39748745 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.02865636 |
3 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.99745264 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 1.97978916 |
5 | Insulin secretion_Homo sapiens_hsa04911 | 1.96959218 |
6 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.91137890 |
7 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.91093797 |
8 | Long-term potentiation_Homo sapiens_hsa04720 | 1.89461960 |
9 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.76395129 |
10 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.76098823 |
11 | Salivary secretion_Homo sapiens_hsa04970 | 1.70210523 |
12 | Taste transduction_Homo sapiens_hsa04742 | 1.67192396 |
13 | GABAergic synapse_Homo sapiens_hsa04727 | 1.66732289 |
14 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.66191588 |
15 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.66076886 |
16 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.57203235 |
17 | Morphine addiction_Homo sapiens_hsa05032 | 1.56716437 |
18 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.55821622 |
19 | Olfactory transduction_Homo sapiens_hsa04740 | 1.54583224 |
20 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.46944492 |
21 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.45813152 |
22 | Renin secretion_Homo sapiens_hsa04924 | 1.42338932 |
23 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.40260340 |
24 | Cocaine addiction_Homo sapiens_hsa05030 | 1.32857586 |
25 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.32292031 |
26 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.29340245 |
27 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.28066517 |
28 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.27759237 |
29 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.26380242 |
30 | Focal adhesion_Homo sapiens_hsa04510 | 1.24924682 |
31 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.23744547 |
32 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.23704977 |
33 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.23358165 |
34 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.21942828 |
35 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.18653167 |
36 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.18113714 |
37 | Gap junction_Homo sapiens_hsa04540 | 1.17457826 |
38 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.17056180 |
39 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.16265106 |
40 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.12398916 |
41 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.10141960 |
42 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.07438528 |
43 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.07412041 |
44 | Long-term depression_Homo sapiens_hsa04730 | 1.04545078 |
45 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.03981914 |
46 | Bladder cancer_Homo sapiens_hsa05219 | 1.01796487 |
47 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.01776438 |
48 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.99206331 |
49 | Axon guidance_Homo sapiens_hsa04360 | 0.98506376 |
50 | Histidine metabolism_Homo sapiens_hsa00340 | 0.98056645 |
51 | Glioma_Homo sapiens_hsa05214 | 0.97564341 |
52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.96928003 |
53 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.96206360 |
54 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.96188807 |
55 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.95815534 |
56 | Melanogenesis_Homo sapiens_hsa04916 | 0.95712555 |
57 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.93439692 |
58 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.92753249 |
59 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.91730749 |
60 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.90950803 |
61 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.90694994 |
62 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.89182353 |
63 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.89048625 |
64 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.88750085 |
65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.86437736 |
66 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.85652718 |
67 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.84650694 |
68 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.82562929 |
69 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.78803073 |
70 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.78566980 |
71 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.75825285 |
72 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.75358621 |
73 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.75355824 |
74 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.74514238 |
75 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.74499436 |
76 | * Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.74014592 |
77 | Adherens junction_Homo sapiens_hsa04520 | 0.73736052 |
78 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.72792538 |
79 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.72472674 |
80 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.71567708 |
81 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.70839565 |
82 | Phagosome_Homo sapiens_hsa04145 | 0.70719732 |
83 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.70092926 |
84 | Amoebiasis_Homo sapiens_hsa05146 | 0.69678883 |
85 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69311316 |
86 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.69255673 |
87 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.68724593 |
88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.67838362 |
89 | Tight junction_Homo sapiens_hsa04530 | 0.67671842 |
90 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.66089232 |
91 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.65739348 |
92 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.64511135 |
93 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63569582 |
94 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.63196636 |
95 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.62154464 |
96 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.61456846 |
97 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.61396941 |
98 | Lysosome_Homo sapiens_hsa04142 | 0.60684307 |
99 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.60182204 |
100 | Thyroid cancer_Homo sapiens_hsa05216 | 0.59736120 |
101 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.58873455 |
102 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.58782224 |
103 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.57972533 |
104 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.56960377 |
105 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.56566710 |
106 | Endocytosis_Homo sapiens_hsa04144 | 0.54873455 |
107 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.53632251 |
108 | Melanoma_Homo sapiens_hsa05218 | 0.53430928 |
109 | Endometrial cancer_Homo sapiens_hsa05213 | 0.53232221 |
110 | Bile secretion_Homo sapiens_hsa04976 | 0.53197379 |
111 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.53162687 |
112 | Pathways in cancer_Homo sapiens_hsa05200 | 0.53138217 |
113 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.52949019 |
114 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.51618498 |
115 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.51516242 |
116 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50087485 |
117 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.48485690 |
118 | Circadian rhythm_Homo sapiens_hsa04710 | 0.48378448 |
119 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.48095942 |
120 | Mineral absorption_Homo sapiens_hsa04978 | 0.48022408 |
121 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.47333154 |
122 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.46975653 |
123 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.44225763 |
124 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.44016534 |
125 | Prion diseases_Homo sapiens_hsa05020 | 0.43705447 |
126 | Insulin resistance_Homo sapiens_hsa04931 | 0.40124902 |
127 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.39521026 |