

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.05089043 |
| 2 | eosinophil chemotaxis (GO:0048245) | 6.13488922 |
| 3 | DNA deamination (GO:0045006) | 6.12908069 |
| 4 | cytidine deamination (GO:0009972) | 5.66358343 |
| 5 | cytidine metabolic process (GO:0046087) | 5.66358343 |
| 6 | cytidine catabolic process (GO:0006216) | 5.66358343 |
| 7 | eosinophil migration (GO:0072677) | 5.54428401 |
| 8 | protein prenylation (GO:0018342) | 5.49682306 |
| 9 | prenylation (GO:0097354) | 5.49682306 |
| 10 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 5.38151933 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.30971165 |
| 12 | proteasome assembly (GO:0043248) | 5.19813193 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.02101677 |
| 14 | ATP synthesis coupled proton transport (GO:0015986) | 5.02101677 |
| 15 | L-fucose catabolic process (GO:0042355) | 4.97873686 |
| 16 | fucose catabolic process (GO:0019317) | 4.97873686 |
| 17 | L-fucose metabolic process (GO:0042354) | 4.97873686 |
| 18 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.93020166 |
| 19 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.80040934 |
| 20 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.49612030 |
| 21 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 4.48535810 |
| 22 | protein neddylation (GO:0045116) | 4.40627388 |
| 23 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.20876902 |
| 24 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.20557854 |
| 25 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.10436060 |
| 26 | chaperone-mediated protein transport (GO:0072321) | 4.05188709 |
| 27 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.01976199 |
| 28 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.93483748 |
| 29 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.93483748 |
| 30 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.93483748 |
| 31 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.89966593 |
| 32 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.89966593 |
| 33 | regulation of mononuclear cell migration (GO:0071675) | 3.88009271 |
| 34 | DNA demethylation (GO:0080111) | 3.84818430 |
| 35 | respiratory electron transport chain (GO:0022904) | 3.84681561 |
| 36 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.81653111 |
| 37 | electron transport chain (GO:0022900) | 3.79609269 |
| 38 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.79049738 |
| 39 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.79049738 |
| 40 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.79049738 |
| 41 | negative regulation of Ras GTPase activity (GO:0034261) | 3.78236545 |
| 42 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.77933623 |
| 43 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.76116736 |
| 44 | termination of RNA polymerase III transcription (GO:0006386) | 3.76116736 |
| 45 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.75459284 |
| 46 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.75459284 |
| 47 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.72280080 |
| 48 | negative regulation of ligase activity (GO:0051352) | 3.72280080 |
| 49 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.72075802 |
| 50 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.66818080 |
| 51 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 3.49090888 |
| 52 | macrophage chemotaxis (GO:0048246) | 3.47749260 |
| 53 | protein complex biogenesis (GO:0070271) | 3.47525473 |
| 54 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.37239384 |
| 55 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.36919114 |
| 56 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.36919114 |
| 57 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.36842203 |
| 58 | metallo-sulfur cluster assembly (GO:0031163) | 3.27324346 |
| 59 | iron-sulfur cluster assembly (GO:0016226) | 3.27324346 |
| 60 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.23716667 |
| 61 | intracellular protein transmembrane import (GO:0044743) | 3.22805185 |
| 62 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.22060295 |
| 63 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.22060295 |
| 64 | NADH dehydrogenase complex assembly (GO:0010257) | 3.22060295 |
| 65 | DNA dealkylation (GO:0035510) | 3.20475916 |
| 66 | sequestering of actin monomers (GO:0042989) | 3.20139572 |
| 67 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.19363786 |
| 68 | respiratory chain complex IV assembly (GO:0008535) | 3.18721698 |
| 69 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.17079154 |
| 70 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.13547680 |
| 71 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.10684064 |
| 72 | regulation of sister chromatid cohesion (GO:0007063) | 3.04558558 |
| 73 | positive regulation of ligase activity (GO:0051351) | 3.03587120 |
| 74 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.00007691 |
| 75 | non-recombinational repair (GO:0000726) | 3.00007691 |
| 76 | positive regulation of cell cycle arrest (GO:0071158) | 2.99659299 |
| 77 | autophagic vacuole fusion (GO:0000046) | 2.98683428 |
| 78 | regulation of cellular amine metabolic process (GO:0033238) | 2.97623116 |
| 79 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.97514775 |
| 80 | inner mitochondrial membrane organization (GO:0007007) | 2.96664353 |
| 81 | hydrogen ion transmembrane transport (GO:1902600) | 2.92609701 |
| 82 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.91286085 |
| 83 | GPI anchor biosynthetic process (GO:0006506) | 2.89404994 |
| 84 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.88922921 |
| 85 | ATP biosynthetic process (GO:0006754) | 2.85818621 |
| 86 | GPI anchor metabolic process (GO:0006505) | 2.82744197 |
| 87 | branch elongation of an epithelium (GO:0060602) | 2.82514371 |
| 88 | cullin deneddylation (GO:0010388) | 2.80643145 |
| 89 | platelet dense granule organization (GO:0060155) | 2.79466956 |
| 90 | monocyte chemotaxis (GO:0002548) | 2.78026328 |
| 91 | cytochrome complex assembly (GO:0017004) | 2.77927984 |
| 92 | protein deneddylation (GO:0000338) | 2.75362123 |
| 93 | proton transport (GO:0015992) | 2.74570171 |
| 94 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 2.72816131 |
| 95 | coenzyme A biosynthetic process (GO:0015937) | 2.72580158 |
| 96 | translation (GO:0006412) | 2.72496730 |
| 97 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.72301524 |
| 98 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.71050037 |
| 99 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.69493262 |
| 100 | regulation of mitochondrial translation (GO:0070129) | 2.68988858 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.62280595 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.05398487 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.64127939 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.61627495 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.59844115 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.30799590 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.16228145 |
| 8 | GATA1_22025678_ChIP-Seq_K562_Human | 2.83606214 |
| 9 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.79285313 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.77356174 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.69362035 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.66773286 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.56919996 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.49141892 |
| 15 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.41255133 |
| 16 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.37751240 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.37115868 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.36324109 |
| 19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.29678234 |
| 20 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.29131406 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.27249631 |
| 22 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.22975180 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.19274682 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.16602490 |
| 25 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.89797569 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.84792868 |
| 27 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.81069591 |
| 28 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.78219435 |
| 29 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.78073867 |
| 30 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.72292601 |
| 31 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.71780024 |
| 32 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.52607761 |
| 33 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.51112261 |
| 34 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.46321515 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.44686207 |
| 36 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.43635726 |
| 37 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.41343485 |
| 38 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.40844783 |
| 39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.37898009 |
| 40 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.37246730 |
| 41 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.34368020 |
| 42 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.33982153 |
| 43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.31740163 |
| 44 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.28292601 |
| 45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.27725104 |
| 46 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.26758933 |
| 47 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26628113 |
| 48 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.25967661 |
| 49 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.25527819 |
| 50 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24617979 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.23544346 |
| 52 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.23428851 |
| 53 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.22776743 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.21565580 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.21565580 |
| 56 | EWS_26573619_Chip-Seq_HEK293_Human | 1.21199115 |
| 57 | FUS_26573619_Chip-Seq_HEK293_Human | 1.21003679 |
| 58 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.17541458 |
| 59 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.13709534 |
| 60 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.13211268 |
| 61 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.12604414 |
| 62 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.10618990 |
| 63 | AR_20517297_ChIP-Seq_VCAP_Human | 1.09304955 |
| 64 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.08958557 |
| 65 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08925684 |
| 66 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.07629121 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.07558605 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.07558605 |
| 69 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.03209426 |
| 70 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.02778146 |
| 71 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.02361210 |
| 72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.99327877 |
| 73 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.99022794 |
| 74 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98835685 |
| 75 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.96566922 |
| 76 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.95325540 |
| 77 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.95155893 |
| 78 | P300_19829295_ChIP-Seq_ESCs_Human | 0.93882677 |
| 79 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.93149153 |
| 80 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.92430106 |
| 81 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.92319936 |
| 82 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.90877377 |
| 83 | NCOR_22424771_ChIP-Seq_293T_Human | 0.89981133 |
| 84 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.89882269 |
| 85 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.88774833 |
| 86 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.88641156 |
| 87 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.87655519 |
| 88 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.87617477 |
| 89 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.86759321 |
| 90 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.86410687 |
| 91 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.86295126 |
| 92 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.85965784 |
| 93 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84556296 |
| 94 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.82838297 |
| 95 | GATA3_26560356_Chip-Seq_TH1_Human | 0.79865402 |
| 96 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.79659531 |
| 97 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.79578966 |
| 98 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.79578966 |
| 99 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.79255029 |
| 100 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.78069049 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 7.01828219 |
| 2 | MP0006082_CNS_inflammation | 3.41624510 |
| 3 | MP0003646_muscle_fatigue | 3.10133197 |
| 4 | MP0002102_abnormal_ear_morphology | 2.90186290 |
| 5 | MP0005671_abnormal_response_to | 2.62249557 |
| 6 | MP0005645_abnormal_hypothalamus_physiol | 2.41440605 |
| 7 | MP0001919_abnormal_reproductive_system | 2.37359041 |
| 8 | MP0002234_abnormal_pharynx_morphology | 2.36716205 |
| 9 | MP0008058_abnormal_DNA_repair | 2.29544180 |
| 10 | MP0000372_irregular_coat_pigmentation | 2.25092842 |
| 11 | MP0002163_abnormal_gland_morphology | 2.13037437 |
| 12 | MP0009379_abnormal_foot_pigmentation | 2.02948274 |
| 13 | MP0008872_abnormal_physiological_respon | 1.86102396 |
| 14 | MP0006292_abnormal_olfactory_placode | 1.81679926 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 1.76073877 |
| 16 | MP0001664_abnormal_digestion | 1.72279806 |
| 17 | MP0002751_abnormal_autonomic_nervous | 1.72000123 |
| 18 | MP0003303_peritoneal_inflammation | 1.67139605 |
| 19 | MP0004145_abnormal_muscle_electrophysio | 1.66762774 |
| 20 | MP0001663_abnormal_digestive_system | 1.64222363 |
| 21 | MP0005389_reproductive_system_phenotype | 1.62518792 |
| 22 | MP0008877_abnormal_DNA_methylation | 1.62423292 |
| 23 | MP0003878_abnormal_ear_physiology | 1.60028151 |
| 24 | MP0005377_hearing/vestibular/ear_phenot | 1.60028151 |
| 25 | MP0002876_abnormal_thyroid_physiology | 1.58739258 |
| 26 | MP0001293_anophthalmia | 1.53674888 |
| 27 | MP0002277_abnormal_respiratory_mucosa | 1.53155350 |
| 28 | MP0002837_dystrophic_cardiac_calcinosis | 1.50746626 |
| 29 | MP0005084_abnormal_gallbladder_morpholo | 1.49714510 |
| 30 | MP0003718_maternal_effect | 1.47742119 |
| 31 | MP0000467_abnormal_esophagus_morphology | 1.41123434 |
| 32 | MP0001764_abnormal_homeostasis | 1.39443398 |
| 33 | MP0003011_delayed_dark_adaptation | 1.37442881 |
| 34 | MP0008789_abnormal_olfactory_epithelium | 1.35470209 |
| 35 | MP0003806_abnormal_nucleotide_metabolis | 1.30112153 |
| 36 | MP0003195_calcinosis | 1.29927456 |
| 37 | MP0005379_endocrine/exocrine_gland_phen | 1.29447331 |
| 38 | MP0003786_premature_aging | 1.29152676 |
| 39 | MP0009785_altered_susceptibility_to | 1.27660670 |
| 40 | MP0005253_abnormal_eye_physiology | 1.26020675 |
| 41 | MP0002006_tumorigenesis | 1.25384183 |
| 42 | MP0002938_white_spotting | 1.24568475 |
| 43 | MP0001873_stomach_inflammation | 1.24155453 |
| 44 | MP0001529_abnormal_vocalization | 1.23491259 |
| 45 | MP0003763_abnormal_thymus_physiology | 1.17461980 |
| 46 | MP0004142_abnormal_muscle_tone | 1.16958122 |
| 47 | MP0003937_abnormal_limbs/digits/tail_de | 1.15561640 |
| 48 | MP0009333_abnormal_splenocyte_physiolog | 1.14146481 |
| 49 | MP0005075_abnormal_melanosome_morpholog | 1.12651427 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 1.11409123 |
| 51 | MP0004147_increased_porphyrin_level | 1.10637731 |
| 52 | MP0000490_abnormal_crypts_of | 1.08482036 |
| 53 | MP0001485_abnormal_pinna_reflex | 1.06355327 |
| 54 | MP0009697_abnormal_copulation | 1.04644911 |
| 55 | MP0005381_digestive/alimentary_phenotyp | 1.04284408 |
| 56 | MP0002166_altered_tumor_susceptibility | 1.03238148 |
| 57 | MP0006276_abnormal_autonomic_nervous | 1.01821981 |
| 58 | MP0002736_abnormal_nociception_after | 1.01311536 |
| 59 | MP0001835_abnormal_antigen_presentation | 0.99664623 |
| 60 | MP0001905_abnormal_dopamine_level | 0.97603992 |
| 61 | MP0004885_abnormal_endolymph | 0.97004003 |
| 62 | MP0005332_abnormal_amino_acid | 0.96519518 |
| 63 | MP0006036_abnormal_mitochondrial_physio | 0.95864025 |
| 64 | MP0000026_abnormal_inner_ear | 0.94897605 |
| 65 | MP0003693_abnormal_embryo_hatching | 0.93117774 |
| 66 | MP0002148_abnormal_hypersensitivity_rea | 0.88576643 |
| 67 | MP0003186_abnormal_redox_activity | 0.87232791 |
| 68 | MP0002210_abnormal_sex_determination | 0.86226384 |
| 69 | MP0008995_early_reproductive_senescence | 0.85171674 |
| 70 | MP0005551_abnormal_eye_electrophysiolog | 0.84916279 |
| 71 | MP0009764_decreased_sensitivity_to | 0.82309111 |
| 72 | MP0005499_abnormal_olfactory_system | 0.82105418 |
| 73 | MP0005394_taste/olfaction_phenotype | 0.82105418 |
| 74 | MP0002138_abnormal_hepatobiliary_system | 0.81739230 |
| 75 | MP0001800_abnormal_humoral_immune | 0.81543280 |
| 76 | MP0005166_decreased_susceptibility_to | 0.81291120 |
| 77 | MP0000383_abnormal_hair_follicle | 0.81264166 |
| 78 | MP0003283_abnormal_digestive_organ | 0.78519685 |
| 79 | MP0001984_abnormal_olfaction | 0.78075675 |
| 80 | MP0001963_abnormal_hearing_physiology | 0.77291234 |
| 81 | MP0004043_abnormal_pH_regulation | 0.77062782 |
| 82 | MP0002019_abnormal_tumor_incidence | 0.75763969 |
| 83 | MP0005167_abnormal_blood-brain_barrier | 0.75511197 |
| 84 | MP0003567_abnormal_fetal_cardiomyocyte | 0.72938810 |
| 85 | MP0005410_abnormal_fertilization | 0.71742722 |
| 86 | MP0001286_abnormal_eye_development | 0.71335134 |
| 87 | MP0005000_abnormal_immune_tolerance | 0.70839453 |
| 88 | MP0003122_maternal_imprinting | 0.70591800 |
| 89 | MP0002272_abnormal_nervous_system | 0.69436865 |
| 90 | MP0002109_abnormal_limb_morphology | 0.69309301 |
| 91 | MP0003136_yellow_coat_color | 0.69073703 |
| 92 | MP0010155_abnormal_intestine_physiology | 0.68801875 |
| 93 | MP0003880_abnormal_central_pattern | 0.68564404 |
| 94 | MP0001119_abnormal_female_reproductive | 0.67421669 |
| 95 | MP0005387_immune_system_phenotype | 0.67086422 |
| 96 | MP0001790_abnormal_immune_system | 0.67086422 |
| 97 | MP0005360_urolithiasis | 0.66878289 |
| 98 | MP0000049_abnormal_middle_ear | 0.66741913 |
| 99 | MP0003866_abnormal_defecation | 0.66670287 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.66254604 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.84437153 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.54621107 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.34799542 |
| 4 | Acute encephalopathy (HP:0006846) | 4.07218159 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.03179327 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.95379284 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.94174929 |
| 8 | Increased CSF lactate (HP:0002490) | 3.92807178 |
| 9 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.85041934 |
| 10 | Hepatic necrosis (HP:0002605) | 3.82319435 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.64206182 |
| 12 | Aplastic anemia (HP:0001915) | 3.59677327 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 3.54685304 |
| 14 | Renal Fanconi syndrome (HP:0001994) | 3.38014056 |
| 15 | Duplicated collecting system (HP:0000081) | 3.37107861 |
| 16 | Lactic acidosis (HP:0003128) | 3.26609274 |
| 17 | Abnormality of the renal collecting system (HP:0004742) | 3.26462343 |
| 18 | Large for gestational age (HP:0001520) | 3.19171024 |
| 19 | Cerebral edema (HP:0002181) | 3.16584447 |
| 20 | Ureteral stenosis (HP:0000071) | 3.12100264 |
| 21 | Increased serum lactate (HP:0002151) | 3.04984757 |
| 22 | Pancreatic cysts (HP:0001737) | 3.03243831 |
| 23 | Increased intramyocellular lipid droplets (HP:0012240) | 3.03170796 |
| 24 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.89897369 |
| 25 | Exercise intolerance (HP:0003546) | 2.88287674 |
| 26 | Ureteral obstruction (HP:0006000) | 2.84351543 |
| 27 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.71554120 |
| 28 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.69828134 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.69828134 |
| 30 | Optic disc pallor (HP:0000543) | 2.68568882 |
| 31 | Respiratory failure (HP:0002878) | 2.66250012 |
| 32 | Exertional dyspnea (HP:0002875) | 2.64268431 |
| 33 | Long foot (HP:0001833) | 2.61283608 |
| 34 | Abnormality of urine glucose concentration (HP:0011016) | 2.53358511 |
| 35 | Glycosuria (HP:0003076) | 2.53358511 |
| 36 | Colon cancer (HP:0003003) | 2.52770499 |
| 37 | True hermaphroditism (HP:0010459) | 2.50186430 |
| 38 | Pancreatic fibrosis (HP:0100732) | 2.50176061 |
| 39 | Adactyly (HP:0009776) | 2.45483347 |
| 40 | Increased muscle lipid content (HP:0009058) | 2.41185146 |
| 41 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.40424082 |
| 42 | Generalized aminoaciduria (HP:0002909) | 2.40010890 |
| 43 | Oral leukoplakia (HP:0002745) | 2.23738674 |
| 44 | Lethargy (HP:0001254) | 2.21734083 |
| 45 | CNS demyelination (HP:0007305) | 2.18855560 |
| 46 | Abnormality of midbrain morphology (HP:0002418) | 2.18584097 |
| 47 | Molar tooth sign on MRI (HP:0002419) | 2.18584097 |
| 48 | Abnormality of the renal cortex (HP:0011035) | 2.18475193 |
| 49 | Hypoproteinemia (HP:0003075) | 2.18309119 |
| 50 | Renal cortical cysts (HP:0000803) | 2.17183823 |
| 51 | Brushfield spots (HP:0001088) | 2.16814790 |
| 52 | IgG deficiency (HP:0004315) | 2.16484162 |
| 53 | Congenital stationary night blindness (HP:0007642) | 2.16175061 |
| 54 | Hypoplastic pelvis (HP:0008839) | 2.13676927 |
| 55 | Leukodystrophy (HP:0002415) | 2.13065185 |
| 56 | Abnormality of renal resorption (HP:0011038) | 2.12237587 |
| 57 | Methylmalonic aciduria (HP:0012120) | 2.11485058 |
| 58 | Abnormality of alanine metabolism (HP:0010916) | 2.08619526 |
| 59 | Hyperalaninemia (HP:0003348) | 2.08619526 |
| 60 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.08619526 |
| 61 | Dry hair (HP:0011359) | 2.07703886 |
| 62 | Type I transferrin isoform profile (HP:0003642) | 2.05974055 |
| 63 | Congenital, generalized hypertrichosis (HP:0004540) | 1.99559508 |
| 64 | Reticulocytopenia (HP:0001896) | 1.99473247 |
| 65 | Nephronophthisis (HP:0000090) | 1.96519810 |
| 66 | Hyperphosphaturia (HP:0003109) | 1.91655334 |
| 67 | Methylmalonic acidemia (HP:0002912) | 1.89435826 |
| 68 | Myoglobinuria (HP:0002913) | 1.88707843 |
| 69 | Respiratory difficulties (HP:0002880) | 1.87526963 |
| 70 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.87339040 |
| 71 | Dicarboxylic aciduria (HP:0003215) | 1.87339040 |
| 72 | Abolished electroretinogram (ERG) (HP:0000550) | 1.86962163 |
| 73 | Abnormal number of erythroid precursors (HP:0012131) | 1.86082419 |
| 74 | Abnormality of placental membranes (HP:0011409) | 1.83729447 |
| 75 | Amniotic constriction ring (HP:0009775) | 1.83729447 |
| 76 | Severe muscular hypotonia (HP:0006829) | 1.80402540 |
| 77 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.79310924 |
| 78 | Severe combined immunodeficiency (HP:0004430) | 1.78536356 |
| 79 | Increased serum pyruvate (HP:0003542) | 1.78016585 |
| 80 | Abnormal drinking behavior (HP:0030082) | 1.77939365 |
| 81 | Polydipsia (HP:0001959) | 1.77939365 |
| 82 | Metabolic acidosis (HP:0001942) | 1.77655764 |
| 83 | Autoimmune thrombocytopenia (HP:0001973) | 1.77612837 |
| 84 | Pancytopenia (HP:0001876) | 1.77305711 |
| 85 | IgM deficiency (HP:0002850) | 1.76139807 |
| 86 | Rhabdomyolysis (HP:0003201) | 1.75062652 |
| 87 | Sclerocornea (HP:0000647) | 1.74624664 |
| 88 | Abnormality of the prostate (HP:0008775) | 1.74501513 |
| 89 | Progressive muscle weakness (HP:0003323) | 1.72398491 |
| 90 | Medial flaring of the eyebrow (HP:0010747) | 1.70198583 |
| 91 | Broad-based gait (HP:0002136) | 1.68786748 |
| 92 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.67820977 |
| 93 | Abnormality of the renal medulla (HP:0100957) | 1.66120910 |
| 94 | Clubbing of toes (HP:0100760) | 1.64295024 |
| 95 | Exercise-induced muscle cramps (HP:0003710) | 1.62805814 |
| 96 | Chorioretinal coloboma (HP:0000567) | 1.62752022 |
| 97 | Posterior subcapsular cataract (HP:0007787) | 1.62047511 |
| 98 | Abnormality of glycolysis (HP:0004366) | 1.61737584 |
| 99 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.60030825 |
| 100 | Autoamputation (HP:0001218) | 1.59054288 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MKNK2 | 6.79279383 |
| 2 | MKNK1 | 4.26958036 |
| 3 | VRK2 | 3.74697678 |
| 4 | TAOK2 | 2.87623138 |
| 5 | ZAK | 2.85412571 |
| 6 | TAOK1 | 2.47258225 |
| 7 | TXK | 2.45936738 |
| 8 | VRK1 | 2.33827781 |
| 9 | BUB1 | 2.28850807 |
| 10 | MAP3K3 | 2.25003205 |
| 11 | MAP3K11 | 2.23170657 |
| 12 | MAP4K2 | 2.16961535 |
| 13 | SRPK1 | 2.11397266 |
| 14 | TLK1 | 1.85415440 |
| 15 | WNK4 | 1.84952032 |
| 16 | BCKDK | 1.72097916 |
| 17 | KDR | 1.70288546 |
| 18 | MST4 | 1.69070273 |
| 19 | STK39 | 1.66575522 |
| 20 | JAK3 | 1.63818797 |
| 21 | STK16 | 1.63002681 |
| 22 | NUAK1 | 1.54101460 |
| 23 | PINK1 | 1.46596930 |
| 24 | ADRBK2 | 1.35027532 |
| 25 | TIE1 | 1.31788925 |
| 26 | WNK3 | 1.30422097 |
| 27 | GRK1 | 1.28743335 |
| 28 | TAF1 | 1.27335638 |
| 29 | BMPR1B | 1.23352394 |
| 30 | NME1 | 1.13947939 |
| 31 | TRIM28 | 1.12627115 |
| 32 | STK24 | 1.06770852 |
| 33 | ABL2 | 1.05652554 |
| 34 | INSRR | 1.02001370 |
| 35 | PLK3 | 1.01863431 |
| 36 | PRKCQ | 1.01111919 |
| 37 | EIF2AK3 | 0.99739402 |
| 38 | CDC7 | 0.99628706 |
| 39 | MAP2K3 | 0.99579991 |
| 40 | DYRK1A | 0.94178853 |
| 41 | TSSK6 | 0.94032415 |
| 42 | MAP3K12 | 0.89635449 |
| 43 | CCNB1 | 0.87549518 |
| 44 | TESK2 | 0.86783000 |
| 45 | CHEK2 | 0.86206570 |
| 46 | CSNK1G3 | 0.85825339 |
| 47 | TAOK3 | 0.82423720 |
| 48 | OBSCN | 0.81519245 |
| 49 | PASK | 0.79237899 |
| 50 | DYRK2 | 0.77855121 |
| 51 | MAP3K5 | 0.77153116 |
| 52 | CDK19 | 0.75496064 |
| 53 | NEK1 | 0.75371696 |
| 54 | EPHB2 | 0.70654734 |
| 55 | CSNK1G1 | 0.69451449 |
| 56 | OXSR1 | 0.67488036 |
| 57 | BCR | 0.65624322 |
| 58 | MAPKAPK5 | 0.64757822 |
| 59 | CSNK1G2 | 0.61724883 |
| 60 | CSNK1A1L | 0.59405173 |
| 61 | CDK8 | 0.59310248 |
| 62 | MUSK | 0.57530526 |
| 63 | ITK | 0.51538551 |
| 64 | PHKG2 | 0.48388802 |
| 65 | PHKG1 | 0.48388802 |
| 66 | CSNK1A1 | 0.48228344 |
| 67 | FES | 0.46906310 |
| 68 | RPS6KA5 | 0.44235816 |
| 69 | MAP2K7 | 0.43879826 |
| 70 | FRK | 0.43594708 |
| 71 | PIK3CG | 0.42936230 |
| 72 | PBK | 0.42826351 |
| 73 | PLK4 | 0.42157307 |
| 74 | EIF2AK2 | 0.40965711 |
| 75 | PDK2 | 0.40740241 |
| 76 | GRK5 | 0.39532843 |
| 77 | DAPK3 | 0.39409529 |
| 78 | MYLK | 0.38425043 |
| 79 | RPS6KA4 | 0.38375574 |
| 80 | DAPK1 | 0.38365592 |
| 81 | GRK7 | 0.37436946 |
| 82 | AURKA | 0.37360530 |
| 83 | PLK2 | 0.36481963 |
| 84 | CSNK2A1 | 0.35827478 |
| 85 | TGFBR1 | 0.35809000 |
| 86 | ILK | 0.35588611 |
| 87 | WEE1 | 0.35005184 |
| 88 | CSNK2A2 | 0.34234131 |
| 89 | MAP4K1 | 0.33685603 |
| 90 | MAPKAPK3 | 0.33356675 |
| 91 | ERBB3 | 0.32731717 |
| 92 | TEC | 0.30340357 |
| 93 | ADRBK1 | 0.30156904 |
| 94 | PLK1 | 0.29948477 |
| 95 | ATR | 0.27978926 |
| 96 | AURKB | 0.27612815 |
| 97 | LIMK1 | 0.26180521 |
| 98 | PRKCE | 0.25687248 |
| 99 | SYK | 0.24299613 |
| 100 | PRKCA | 0.24149618 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.24372114 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.81483210 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.26972291 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 3.11744484 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.93044574 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.51937670 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.23057260 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.11750127 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.01906515 |
| 10 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.88015284 |
| 11 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.81661325 |
| 12 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.77962695 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 1.73344050 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.65415227 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.64710929 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.64644280 |
| 17 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.60209153 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.58014754 |
| 19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.51861887 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.50046995 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.49051876 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.48455911 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.46833530 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.42058426 |
| 25 | Allograft rejection_Homo sapiens_hsa05330 | 1.40724745 |
| 26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.39220488 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.34193568 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.33894240 |
| 29 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.31090997 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.30512950 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.29479646 |
| 32 | RNA degradation_Homo sapiens_hsa03018 | 1.23666144 |
| 33 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.20521201 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.17249052 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.14856209 |
| 36 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.11316147 |
| 37 | RNA transport_Homo sapiens_hsa03013 | 1.09883001 |
| 38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.09273146 |
| 39 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.08753702 |
| 40 | Basal transcription factors_Homo sapiens_hsa03022 | 1.08306944 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.07797499 |
| 42 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.07777014 |
| 43 | Spliceosome_Homo sapiens_hsa03040 | 1.07092669 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 1.06243967 |
| 45 | Phototransduction_Homo sapiens_hsa04744 | 1.01894607 |
| 46 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.96962066 |
| 47 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.95288726 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.89998757 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.89155848 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.87257781 |
| 51 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.87244264 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.86106845 |
| 53 | Base excision repair_Homo sapiens_hsa03410 | 0.85763414 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.85701768 |
| 55 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.83339640 |
| 56 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.82746389 |
| 57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.77316473 |
| 58 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.74842923 |
| 59 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73982037 |
| 60 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.72252945 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71746652 |
| 62 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.68951264 |
| 63 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.68451506 |
| 64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.67952214 |
| 65 | Carbon metabolism_Homo sapiens_hsa01200 | 0.67693750 |
| 66 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.67478022 |
| 67 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.66263516 |
| 68 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.65316431 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.60134188 |
| 70 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.60007021 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.59925102 |
| 72 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.59168318 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.58331079 |
| 74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.58137166 |
| 75 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.56307101 |
| 76 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.55960919 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.55731690 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.55495647 |
| 79 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.53738152 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.53733767 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51831851 |
| 82 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.51601372 |
| 83 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.50531018 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.50251458 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49183658 |
| 86 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.46795853 |
| 87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.44469114 |
| 88 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.44302221 |
| 89 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.44127552 |
| 90 | Viral myocarditis_Homo sapiens_hsa05416 | 0.43974543 |
| 91 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.42801701 |
| 92 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.42121724 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.40113036 |
| 94 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.39135312 |
| 95 | Alcoholism_Homo sapiens_hsa05034 | 0.38662803 |
| 96 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37413874 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36266290 |
| 98 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.35436092 |
| 99 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.33355862 |
| 100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.31639229 |

