

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to pheromone (GO:0019236) | 7.42980092 |
| 2 | DNA deamination (GO:0045006) | 6.23063533 |
| 3 | rRNA modification (GO:0000154) | 5.59001484 |
| 4 | fucose catabolic process (GO:0019317) | 5.27416866 |
| 5 | L-fucose metabolic process (GO:0042354) | 5.27416866 |
| 6 | L-fucose catabolic process (GO:0042355) | 5.27416866 |
| 7 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 5.03422071 |
| 8 | ribosomal small subunit assembly (GO:0000028) | 4.94289975 |
| 9 | rRNA methylation (GO:0031167) | 4.93154928 |
| 10 | purine deoxyribonucleotide catabolic process (GO:0009155) | 4.80528694 |
| 11 | regulation of chronic inflammatory response (GO:0002676) | 4.67780477 |
| 12 | proteasome assembly (GO:0043248) | 4.51919946 |
| 13 | cullin deneddylation (GO:0010388) | 4.36520551 |
| 14 | neuronal action potential propagation (GO:0019227) | 4.16698866 |
| 15 | pseudouridine synthesis (GO:0001522) | 4.14411012 |
| 16 | amino acid salvage (GO:0043102) | 4.10772315 |
| 17 | L-methionine salvage (GO:0071267) | 4.10772315 |
| 18 | L-methionine biosynthetic process (GO:0071265) | 4.10772315 |
| 19 | GTP biosynthetic process (GO:0006183) | 4.07490694 |
| 20 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.04555376 |
| 21 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.02796156 |
| 22 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.01019280 |
| 23 | protein deneddylation (GO:0000338) | 3.98885478 |
| 24 | UTP metabolic process (GO:0046051) | 3.97866134 |
| 25 | negative regulation of JAK-STAT cascade (GO:0046426) | 3.95333466 |
| 26 | maturation of SSU-rRNA (GO:0030490) | 3.89605978 |
| 27 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.76999058 |
| 28 | amino acid activation (GO:0043038) | 3.70896042 |
| 29 | tRNA aminoacylation (GO:0043039) | 3.70896042 |
| 30 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.70811451 |
| 31 | base-excision repair, AP site formation (GO:0006285) | 3.70277109 |
| 32 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.66598840 |
| 33 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.66598840 |
| 34 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.66598840 |
| 35 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.66411466 |
| 36 | tRNA aminoacylation for protein translation (GO:0006418) | 3.62891419 |
| 37 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.61927886 |
| 38 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.61853434 |
| 39 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.61853434 |
| 40 | UTP biosynthetic process (GO:0006228) | 3.60420285 |
| 41 | CTP biosynthetic process (GO:0006241) | 3.55927476 |
| 42 | CTP metabolic process (GO:0046036) | 3.55927476 |
| 43 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.54263402 |
| 44 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.47702196 |
| 45 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.47438593 |
| 46 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.46934008 |
| 47 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.46934008 |
| 48 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.45276903 |
| 49 | protein neddylation (GO:0045116) | 3.44584143 |
| 50 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.41593350 |
| 51 | ATP synthesis coupled proton transport (GO:0015986) | 3.41593350 |
| 52 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.34709277 |
| 53 | negative regulation of ligase activity (GO:0051352) | 3.28551184 |
| 54 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.28551184 |
| 55 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.24796804 |
| 56 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.24723536 |
| 57 | ribosome assembly (GO:0042255) | 3.19081862 |
| 58 | chromatin remodeling at centromere (GO:0031055) | 3.17841942 |
| 59 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.16616830 |
| 60 | platelet dense granule organization (GO:0060155) | 3.13088775 |
| 61 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.12755166 |
| 62 | dopamine transport (GO:0015872) | 3.12223788 |
| 63 | protein complex biogenesis (GO:0070271) | 3.06710176 |
| 64 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.06272880 |
| 65 | AMP metabolic process (GO:0046033) | 3.06050164 |
| 66 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.05549610 |
| 67 | organelle disassembly (GO:1903008) | 3.03878489 |
| 68 | positive regulation of ligase activity (GO:0051351) | 3.01930384 |
| 69 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.01260827 |
| 70 | CENP-A containing nucleosome assembly (GO:0034080) | 3.01050055 |
| 71 | oligosaccharide biosynthetic process (GO:0009312) | 2.99946020 |
| 72 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.99596595 |
| 73 | keratinocyte development (GO:0003334) | 2.99531154 |
| 74 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.93002802 |
| 75 | NADH dehydrogenase complex assembly (GO:0010257) | 2.93002802 |
| 76 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.93002802 |
| 77 | DNA strand renaturation (GO:0000733) | 2.91444376 |
| 78 | termination of RNA polymerase III transcription (GO:0006386) | 2.90186078 |
| 79 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.90186078 |
| 80 | negative regulation of mast cell activation (GO:0033004) | 2.89548302 |
| 81 | deoxyribonucleotide catabolic process (GO:0009264) | 2.88259686 |
| 82 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.88012801 |
| 83 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 2.86025721 |
| 84 | methionine biosynthetic process (GO:0009086) | 2.83391808 |
| 85 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.82072991 |
| 86 | tRNA metabolic process (GO:0006399) | 2.82041885 |
| 87 | protein polyglutamylation (GO:0018095) | 2.80586910 |
| 88 | positive regulation of cell cycle arrest (GO:0071158) | 2.79496643 |
| 89 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.78929538 |
| 90 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.78601790 |
| 91 | ribosomal large subunit biogenesis (GO:0042273) | 2.77649758 |
| 92 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.77426599 |
| 93 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.77426599 |
| 94 | positive regulation of meiotic cell cycle (GO:0051446) | 2.76414101 |
| 95 | protein-cofactor linkage (GO:0018065) | 2.75428674 |
| 96 | fucosylation (GO:0036065) | 2.74402973 |
| 97 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.73881653 |
| 98 | tRNA processing (GO:0008033) | 2.73051724 |
| 99 | methionine metabolic process (GO:0006555) | 2.70920648 |
| 100 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.70672992 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.47607509 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.71164828 |
| 3 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.61528805 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.58376385 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.29328737 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.22359829 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.09187687 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.99786476 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.99256028 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.87227871 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.86658270 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.77786143 |
| 13 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.55288167 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.48109780 |
| 15 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.46635806 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.38872407 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.35599682 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.26765671 |
| 19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.19885971 |
| 20 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.18884415 |
| 21 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.14774872 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.06826014 |
| 23 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.03498689 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.03433173 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.85821814 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 1.85593876 |
| 27 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.83496029 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.82341058 |
| 29 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.81899659 |
| 30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.71490246 |
| 31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.66123615 |
| 32 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65186790 |
| 33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.62528244 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.60156183 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.60112915 |
| 36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.57135070 |
| 37 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.54208518 |
| 38 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.53499195 |
| 39 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.51893929 |
| 40 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.48208685 |
| 41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.47741660 |
| 42 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.46197918 |
| 43 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.41889483 |
| 44 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.41686950 |
| 45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.38647795 |
| 46 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.35466406 |
| 47 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34305076 |
| 48 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.34111574 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.33565702 |
| 50 | GATA1_22025678_ChIP-Seq_K562_Human | 1.31178692 |
| 51 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.30501178 |
| 52 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.25838667 |
| 53 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.25274933 |
| 54 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.22800699 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21802960 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21802960 |
| 57 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21577359 |
| 58 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.20832508 |
| 59 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.20670799 |
| 60 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.19659030 |
| 61 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.19097082 |
| 62 | AR_20517297_ChIP-Seq_VCAP_Human | 1.17752376 |
| 63 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.16313544 |
| 64 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16262785 |
| 65 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.15301896 |
| 66 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.14291918 |
| 67 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.12589496 |
| 68 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.06088671 |
| 69 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.05350245 |
| 70 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.05086201 |
| 71 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.05002869 |
| 72 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.03069620 |
| 73 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03068709 |
| 74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.02819656 |
| 75 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.01873875 |
| 76 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.00389471 |
| 77 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98973582 |
| 78 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.97253473 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.95896544 |
| 80 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.95896544 |
| 81 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.95741987 |
| 82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93094107 |
| 83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93094107 |
| 84 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.92211918 |
| 85 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.91000586 |
| 86 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.90897472 |
| 87 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.88959966 |
| 88 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.87891511 |
| 89 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.87242354 |
| 90 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.87161112 |
| 91 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.86371641 |
| 92 | GATA3_26560356_Chip-Seq_TH2_Human | 0.85738260 |
| 93 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.85505076 |
| 94 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.85478139 |
| 95 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.85476198 |
| 96 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.83892900 |
| 97 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.82668761 |
| 98 | NCOR_22424771_ChIP-Seq_293T_Human | 0.80986626 |
| 99 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.77971589 |
| 100 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.77966834 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005645_abnormal_hypothalamus_physiol | 6.09409204 |
| 2 | MP0003283_abnormal_digestive_organ | 3.67413886 |
| 3 | MP0002138_abnormal_hepatobiliary_system | 3.38486310 |
| 4 | MP0005075_abnormal_melanosome_morpholog | 2.97185470 |
| 5 | MP0008058_abnormal_DNA_repair | 2.94732587 |
| 6 | MP0000685_abnormal_immune_system | 2.88188115 |
| 7 | MP0006292_abnormal_olfactory_placode | 2.51297833 |
| 8 | MP0008995_early_reproductive_senescence | 2.34257768 |
| 9 | MP0002102_abnormal_ear_morphology | 2.30147528 |
| 10 | MP0005671_abnormal_response_to | 2.19232604 |
| 11 | MP0001873_stomach_inflammation | 2.01084410 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 1.95363305 |
| 13 | MP0009697_abnormal_copulation | 1.95260724 |
| 14 | MP0001835_abnormal_antigen_presentation | 1.93461575 |
| 15 | MP0003786_premature_aging | 1.91201359 |
| 16 | MP0000372_irregular_coat_pigmentation | 1.88117767 |
| 17 | MP0004145_abnormal_muscle_electrophysio | 1.87925518 |
| 18 | MP0002653_abnormal_ependyma_morphology | 1.83643921 |
| 19 | MP0003252_abnormal_bile_duct | 1.83001612 |
| 20 | MP0002736_abnormal_nociception_after | 1.66033499 |
| 21 | MP0003186_abnormal_redox_activity | 1.65699847 |
| 22 | MP0001764_abnormal_homeostasis | 1.63177380 |
| 23 | MP0004885_abnormal_endolymph | 1.59853118 |
| 24 | MP0001501_abnormal_sleep_pattern | 1.58750557 |
| 25 | MP0008872_abnormal_physiological_respon | 1.56554760 |
| 26 | MP0001727_abnormal_embryo_implantation | 1.53524675 |
| 27 | MP0004147_increased_porphyrin_level | 1.52602023 |
| 28 | MP0002160_abnormal_reproductive_system | 1.52520828 |
| 29 | MP0002272_abnormal_nervous_system | 1.51154668 |
| 30 | MP0005085_abnormal_gallbladder_physiolo | 1.46071869 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.45420284 |
| 32 | MP0001440_abnormal_grooming_behavior | 1.42742536 |
| 33 | MP0003880_abnormal_central_pattern | 1.42183075 |
| 34 | MP0001968_abnormal_touch/_nociception | 1.41307207 |
| 35 | MP0006072_abnormal_retinal_apoptosis | 1.37533135 |
| 36 | MP0001790_abnormal_immune_system | 1.37474462 |
| 37 | MP0005387_immune_system_phenotype | 1.37474462 |
| 38 | MP0010094_abnormal_chromosome_stability | 1.35912666 |
| 39 | MP0003567_abnormal_fetal_cardiomyocyte | 1.31216909 |
| 40 | MP0003646_muscle_fatigue | 1.31029791 |
| 41 | MP0003195_calcinosis | 1.29996839 |
| 42 | MP0005389_reproductive_system_phenotype | 1.29744808 |
| 43 | MP0003718_maternal_effect | 1.29138064 |
| 44 | MP0005379_endocrine/exocrine_gland_phen | 1.27562321 |
| 45 | MP0005310_abnormal_salivary_gland | 1.26885821 |
| 46 | MP0008789_abnormal_olfactory_epithelium | 1.24934531 |
| 47 | MP0002166_altered_tumor_susceptibility | 1.24773058 |
| 48 | MP0002733_abnormal_thermal_nociception | 1.23518645 |
| 49 | MP0002735_abnormal_chemical_nociception | 1.23240171 |
| 50 | MP0006036_abnormal_mitochondrial_physio | 1.19555608 |
| 51 | MP0001529_abnormal_vocalization | 1.18935436 |
| 52 | MP0001663_abnormal_digestive_system | 1.17060389 |
| 53 | MP0004142_abnormal_muscle_tone | 1.15797228 |
| 54 | MP0002163_abnormal_gland_morphology | 1.15280902 |
| 55 | MP0008877_abnormal_DNA_methylation | 1.15055764 |
| 56 | MP0006054_spinal_hemorrhage | 1.15049428 |
| 57 | MP0001905_abnormal_dopamine_level | 1.09462697 |
| 58 | MP0002148_abnormal_hypersensitivity_rea | 1.09207236 |
| 59 | MP0005408_hypopigmentation | 1.07515842 |
| 60 | MP0001348_abnormal_lacrimal_gland | 1.07189924 |
| 61 | MP0009046_muscle_twitch | 1.05447201 |
| 62 | MP0002876_abnormal_thyroid_physiology | 1.02552454 |
| 63 | MP0002132_abnormal_respiratory_system | 1.02410929 |
| 64 | MP0001800_abnormal_humoral_immune | 1.01956934 |
| 65 | MP0002006_tumorigenesis | 0.99819218 |
| 66 | MP0003806_abnormal_nucleotide_metabolis | 0.99691696 |
| 67 | MP0009333_abnormal_splenocyte_physiolog | 0.94870193 |
| 68 | MP0005551_abnormal_eye_electrophysiolog | 0.92393799 |
| 69 | MP0003136_yellow_coat_color | 0.89878327 |
| 70 | MP0004133_heterotaxia | 0.89765538 |
| 71 | MP0002837_dystrophic_cardiac_calcinosis | 0.87552371 |
| 72 | MP0001119_abnormal_female_reproductive | 0.87212201 |
| 73 | MP0009745_abnormal_behavioral_response | 0.86121517 |
| 74 | MP0001986_abnormal_taste_sensitivity | 0.86067931 |
| 75 | MP0001970_abnormal_pain_threshold | 0.86012991 |
| 76 | MP0002210_abnormal_sex_determination | 0.85126294 |
| 77 | MP0009785_altered_susceptibility_to | 0.79209932 |
| 78 | MP0005253_abnormal_eye_physiology | 0.78377366 |
| 79 | MP0002332_abnormal_exercise_endurance | 0.76148015 |
| 80 | MP0002751_abnormal_autonomic_nervous | 0.75481574 |
| 81 | MP0003045_fibrosis | 0.75375665 |
| 82 | MP0004381_abnormal_hair_follicle | 0.74420878 |
| 83 | MP0000647_abnormal_sebaceous_gland | 0.73633069 |
| 84 | MP0001502_abnormal_circadian_rhythm | 0.72395380 |
| 85 | MP0003943_abnormal_hepatobiliary_system | 0.71749290 |
| 86 | MP0002938_white_spotting | 0.71185648 |
| 87 | MP0000631_abnormal_neuroendocrine_gland | 0.70441827 |
| 88 | MP0002405_respiratory_system_inflammati | 0.69702979 |
| 89 | MP0002184_abnormal_innervation | 0.68823410 |
| 90 | MP0001929_abnormal_gametogenesis | 0.66321414 |
| 91 | MP0005394_taste/olfaction_phenotype | 0.65919606 |
| 92 | MP0005499_abnormal_olfactory_system | 0.65919606 |
| 93 | MP0003866_abnormal_defecation | 0.65685009 |
| 94 | MP0004957_abnormal_blastocyst_morpholog | 0.65528858 |
| 95 | MP0002398_abnormal_bone_marrow | 0.65218399 |
| 96 | MP0005332_abnormal_amino_acid | 0.64913604 |
| 97 | MP0001919_abnormal_reproductive_system | 0.64460976 |
| 98 | MP0005365_abnormal_bile_salt | 0.64094764 |
| 99 | MP0003011_delayed_dark_adaptation | 0.64071752 |
| 100 | MP0005381_digestive/alimentary_phenotyp | 0.63818026 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Septo-optic dysplasia (HP:0100842) | 4.66991546 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.57310247 |
| 3 | Unilateral renal agenesis (HP:0000122) | 4.56689776 |
| 4 | Acute encephalopathy (HP:0006846) | 4.13891463 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.09336723 |
| 6 | Increased CSF lactate (HP:0002490) | 4.09276814 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.88896916 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.85644994 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.72400878 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.70642164 |
| 11 | Dyschromatopsia (HP:0007641) | 3.41877307 |
| 12 | Abnormality of midbrain morphology (HP:0002418) | 3.31694012 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.31694012 |
| 14 | Increased serum lactate (HP:0002151) | 3.22234926 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.20901286 |
| 16 | Hypomagnesemia (HP:0002917) | 3.19890058 |
| 17 | Reticulocytopenia (HP:0001896) | 3.01730028 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 2.93644280 |
| 19 | Cerebral edema (HP:0002181) | 2.87356145 |
| 20 | Cerebral hypomyelination (HP:0006808) | 2.86263672 |
| 21 | Abolished electroretinogram (ERG) (HP:0000550) | 2.85841638 |
| 22 | Optic disc pallor (HP:0000543) | 2.85725328 |
| 23 | Delayed CNS myelination (HP:0002188) | 2.82036701 |
| 24 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.79932419 |
| 25 | Hepatic necrosis (HP:0002605) | 2.79517676 |
| 26 | Respiratory difficulties (HP:0002880) | 2.72826904 |
| 27 | Hypoplasia of the pons (HP:0012110) | 2.69740506 |
| 28 | Abnormality of magnesium homeostasis (HP:0004921) | 2.66297069 |
| 29 | Pancreatic cysts (HP:0001737) | 2.63753137 |
| 30 | Chronic sinusitis (HP:0011109) | 2.59378061 |
| 31 | Abnormality of the pons (HP:0007361) | 2.51452476 |
| 32 | Poor head control (HP:0002421) | 2.48467323 |
| 33 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.46723986 |
| 34 | Exertional dyspnea (HP:0002875) | 2.46034498 |
| 35 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.41868996 |
| 36 | Absent/shortened dynein arms (HP:0200106) | 2.41868996 |
| 37 | Maternal diabetes (HP:0009800) | 2.36792348 |
| 38 | True hermaphroditism (HP:0010459) | 2.36487680 |
| 39 | Colon cancer (HP:0003003) | 2.34382566 |
| 40 | Prostate neoplasm (HP:0100787) | 2.33290788 |
| 41 | 3-Methylglutaconic aciduria (HP:0003535) | 2.32967533 |
| 42 | Abnormality of the renal collecting system (HP:0004742) | 2.31626218 |
| 43 | Absent septum pellucidum (HP:0001331) | 2.30581687 |
| 44 | CNS demyelination (HP:0007305) | 2.25779011 |
| 45 | Pancytopenia (HP:0001876) | 2.25544033 |
| 46 | Lactic acidosis (HP:0003128) | 2.25332499 |
| 47 | Cellular immunodeficiency (HP:0005374) | 2.22917022 |
| 48 | Respiratory failure (HP:0002878) | 2.20007109 |
| 49 | Gonadotropin excess (HP:0000837) | 2.18731834 |
| 50 | Lethargy (HP:0001254) | 2.18464294 |
| 51 | Abnormality of the labia minora (HP:0012880) | 2.17321907 |
| 52 | Glycosuria (HP:0003076) | 2.13493937 |
| 53 | Abnormality of urine glucose concentration (HP:0011016) | 2.13493937 |
| 54 | Increased intramyocellular lipid droplets (HP:0012240) | 2.12957435 |
| 55 | Chronic otitis media (HP:0000389) | 2.12584579 |
| 56 | Exercise intolerance (HP:0003546) | 2.09390090 |
| 57 | Duplicated collecting system (HP:0000081) | 2.07670406 |
| 58 | Broad-based gait (HP:0002136) | 2.06342085 |
| 59 | Emotional lability (HP:0000712) | 2.05458501 |
| 60 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.04323622 |
| 61 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.00950171 |
| 62 | Abnormality of the prostate (HP:0008775) | 1.99680919 |
| 63 | Leukodystrophy (HP:0002415) | 1.98645060 |
| 64 | Neoplasm of the adrenal cortex (HP:0100641) | 1.94618045 |
| 65 | Polyuria (HP:0000103) | 1.93233612 |
| 66 | Type 2 muscle fiber atrophy (HP:0003554) | 1.93001130 |
| 67 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.92161345 |
| 68 | Oral leukoplakia (HP:0002745) | 1.91441448 |
| 69 | Optic nerve hypoplasia (HP:0000609) | 1.90677406 |
| 70 | Horizontal nystagmus (HP:0000666) | 1.88881536 |
| 71 | Amelogenesis imperfecta (HP:0000705) | 1.87202374 |
| 72 | Congenital, generalized hypertrichosis (HP:0004540) | 1.85804454 |
| 73 | Anosmia (HP:0000458) | 1.85337581 |
| 74 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.84102502 |
| 75 | Absent epiphyses (HP:0010577) | 1.84102502 |
| 76 | Abnormality of the septum pellucidum (HP:0007375) | 1.83857660 |
| 77 | IgG deficiency (HP:0004315) | 1.83271876 |
| 78 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.82429447 |
| 79 | Adrenal hypoplasia (HP:0000835) | 1.80961074 |
| 80 | Congenital stationary night blindness (HP:0007642) | 1.80131849 |
| 81 | Narrow forehead (HP:0000341) | 1.80083796 |
| 82 | CNS hypomyelination (HP:0003429) | 1.79946941 |
| 83 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.79395653 |
| 84 | Absent speech (HP:0001344) | 1.78239532 |
| 85 | Limb dystonia (HP:0002451) | 1.77736179 |
| 86 | Hyperphosphaturia (HP:0003109) | 1.77535754 |
| 87 | Abnormality of renal resorption (HP:0011038) | 1.77417117 |
| 88 | Abnormality of T cells (HP:0002843) | 1.75662227 |
| 89 | Hypoplastic pelvis (HP:0008839) | 1.75138157 |
| 90 | Inability to walk (HP:0002540) | 1.74213855 |
| 91 | Progressive microcephaly (HP:0000253) | 1.73661369 |
| 92 | Pancreatic fibrosis (HP:0100732) | 1.72385143 |
| 93 | Poor suck (HP:0002033) | 1.71902761 |
| 94 | Birth length less than 3rd percentile (HP:0003561) | 1.70751434 |
| 95 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.70319434 |
| 96 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.70319434 |
| 97 | Thyroid-stimulating hormone excess (HP:0002925) | 1.69855038 |
| 98 | Alkalosis (HP:0001948) | 1.69382651 |
| 99 | Abnormality of the renal cortex (HP:0011035) | 1.68319556 |
| 100 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.67643939 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 6.37086185 |
| 2 | VRK2 | 3.91057129 |
| 3 | STK16 | 3.59159142 |
| 4 | NUAK1 | 3.33702296 |
| 5 | TAF1 | 3.24392338 |
| 6 | CCNB1 | 2.84952402 |
| 7 | EIF2AK1 | 2.35036315 |
| 8 | ZAK | 2.32245929 |
| 9 | TXK | 2.25632188 |
| 10 | TRIM28 | 2.16731774 |
| 11 | SRPK1 | 2.02234428 |
| 12 | WNK3 | 1.98088187 |
| 13 | NME1 | 1.88690213 |
| 14 | TSSK6 | 1.88432126 |
| 15 | VRK1 | 1.77260311 |
| 16 | TLK1 | 1.73232929 |
| 17 | INSRR | 1.55131748 |
| 18 | GRK1 | 1.46497946 |
| 19 | CDK8 | 1.45440937 |
| 20 | PHKG2 | 1.43387571 |
| 21 | PHKG1 | 1.43387571 |
| 22 | MAPKAPK3 | 1.40839816 |
| 23 | KIT | 1.35646766 |
| 24 | EIF2AK3 | 1.34854766 |
| 25 | PINK1 | 1.30593180 |
| 26 | PLK4 | 1.25354922 |
| 27 | DAPK1 | 1.22154239 |
| 28 | SIK3 | 1.15506331 |
| 29 | PBK | 1.14586256 |
| 30 | PLK3 | 1.12089102 |
| 31 | ADRBK2 | 1.10885074 |
| 32 | CDK19 | 1.06384482 |
| 33 | PASK | 1.05720559 |
| 34 | WEE1 | 1.04925993 |
| 35 | EIF2AK2 | 1.02102154 |
| 36 | PLK2 | 0.98262316 |
| 37 | BRSK2 | 0.97667349 |
| 38 | LATS1 | 0.97435837 |
| 39 | CSNK1G3 | 0.92370088 |
| 40 | JAK3 | 0.91297702 |
| 41 | CSNK1G1 | 0.89927147 |
| 42 | PIK3CA | 0.89525200 |
| 43 | MAP3K12 | 0.89015783 |
| 44 | FER | 0.85699929 |
| 45 | FRK | 0.83389863 |
| 46 | SMG1 | 0.78724920 |
| 47 | CSNK1G2 | 0.78532082 |
| 48 | GRK5 | 0.77361916 |
| 49 | CSNK1A1L | 0.76014106 |
| 50 | OXSR1 | 0.75771317 |
| 51 | BCR | 0.74285265 |
| 52 | DYRK2 | 0.74082428 |
| 53 | MAP2K6 | 0.73209033 |
| 54 | DAPK2 | 0.69074183 |
| 55 | SYK | 0.68587707 |
| 56 | MAP4K2 | 0.66635047 |
| 57 | TIE1 | 0.65551785 |
| 58 | TNIK | 0.65085727 |
| 59 | PDK2 | 0.64797568 |
| 60 | TEC | 0.64638367 |
| 61 | MINK1 | 0.63318318 |
| 62 | TGFBR1 | 0.62615291 |
| 63 | MAP4K1 | 0.62260871 |
| 64 | DAPK3 | 0.61081629 |
| 65 | MATK | 0.60723059 |
| 66 | MAP3K9 | 0.60352443 |
| 67 | PRKCI | 0.59444986 |
| 68 | BUB1 | 0.58453261 |
| 69 | ITK | 0.55369779 |
| 70 | PLK1 | 0.54070907 |
| 71 | BMPR1B | 0.52046246 |
| 72 | SCYL2 | 0.51354921 |
| 73 | CDK9 | 0.48040346 |
| 74 | MAPKAPK5 | 0.47313701 |
| 75 | EPHB2 | 0.46549436 |
| 76 | KDR | 0.45856472 |
| 77 | CDC7 | 0.45309076 |
| 78 | PTK2B | 0.44630819 |
| 79 | BRSK1 | 0.44050083 |
| 80 | RPS6KB2 | 0.43192647 |
| 81 | TYRO3 | 0.43062753 |
| 82 | PRKCQ | 0.39522358 |
| 83 | LYN | 0.38798966 |
| 84 | PRKCG | 0.38188655 |
| 85 | INSR | 0.37147906 |
| 86 | PRKCE | 0.36632197 |
| 87 | MYLK | 0.35783510 |
| 88 | LCK | 0.33863171 |
| 89 | NEK1 | 0.33327351 |
| 90 | RIPK4 | 0.32409736 |
| 91 | NLK | 0.32194618 |
| 92 | PRKACA | 0.31094519 |
| 93 | CSNK2A1 | 0.31009675 |
| 94 | OBSCN | 0.30892022 |
| 95 | STK39 | 0.30078913 |
| 96 | CAMK2D | 0.28401430 |
| 97 | PIK3CG | 0.28017066 |
| 98 | STK4 | 0.27582738 |
| 99 | EPHA4 | 0.27220334 |
| 100 | STK3 | 0.26858215 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.76795129 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.66221546 |
| 3 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.82359219 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 2.62639545 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.57101102 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.54928673 |
| 7 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.47710201 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.34488849 |
| 9 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.30809085 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.29865780 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.29245856 |
| 12 | Parkinsons disease_Homo sapiens_hsa05012 | 2.26094555 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.11846973 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.07506340 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 2.05072470 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.02355891 |
| 17 | Mismatch repair_Homo sapiens_hsa03430 | 1.99066019 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.89668284 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.85483760 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.74629855 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.74405542 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.67492031 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.63127039 |
| 24 | DNA replication_Homo sapiens_hsa03030 | 1.61864729 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.56380169 |
| 26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.55469816 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.54279437 |
| 28 | Base excision repair_Homo sapiens_hsa03410 | 1.42278673 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.37616617 |
| 30 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.30838897 |
| 31 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.21251445 |
| 32 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.20713851 |
| 33 | RNA transport_Homo sapiens_hsa03013 | 1.19260249 |
| 34 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.18197093 |
| 35 | Alzheimers disease_Homo sapiens_hsa05010 | 1.18042724 |
| 36 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.13337605 |
| 37 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.09973990 |
| 38 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.08406981 |
| 39 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.06513167 |
| 40 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.05600004 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.03018019 |
| 42 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.00340092 |
| 43 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.99631686 |
| 44 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90424713 |
| 45 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.89523497 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 0.83012698 |
| 47 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.81944663 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80982752 |
| 49 | Olfactory transduction_Homo sapiens_hsa04740 | 0.79697615 |
| 50 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.79272650 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78871770 |
| 52 | Viral myocarditis_Homo sapiens_hsa05416 | 0.77481999 |
| 53 | Sulfur relay system_Homo sapiens_hsa04122 | 0.76000005 |
| 54 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.73405965 |
| 55 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.73143632 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.71159707 |
| 57 | Peroxisome_Homo sapiens_hsa04146 | 0.71071308 |
| 58 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.70416917 |
| 59 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.66807798 |
| 60 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65445124 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 0.61527551 |
| 62 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61223653 |
| 63 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.60307177 |
| 64 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.59955138 |
| 65 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.59700468 |
| 66 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.57518667 |
| 67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.56359323 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55010753 |
| 69 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.54584183 |
| 70 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.52561299 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.50804095 |
| 72 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.49734181 |
| 73 | Morphine addiction_Homo sapiens_hsa05032 | 0.49051796 |
| 74 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.48497481 |
| 75 | Retinol metabolism_Homo sapiens_hsa00830 | 0.48075813 |
| 76 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.47857488 |
| 77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.46698312 |
| 78 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.46162605 |
| 79 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.45409146 |
| 80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.45256693 |
| 81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.44884236 |
| 82 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.44621406 |
| 83 | Nicotine addiction_Homo sapiens_hsa05033 | 0.42664615 |
| 84 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.42655069 |
| 85 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.40511958 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.39263927 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39240821 |
| 88 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.36417056 |
| 89 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.35711797 |
| 90 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.34409628 |
| 91 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.33848168 |
| 92 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.32485578 |
| 93 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.31975077 |
| 94 | Carbon metabolism_Homo sapiens_hsa01200 | 0.30814383 |
| 95 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.27181834 |
| 96 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.27133218 |
| 97 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.25616154 |
| 98 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.24582560 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.23540016 |
| 100 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.21672574 |

