

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 6.55206503 |
| 2 | DNA deamination (GO:0045006) | 5.84007076 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.09793571 |
| 4 | protein neddylation (GO:0045116) | 4.75072191 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.64429551 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.62642829 |
| 7 | ATP synthesis coupled proton transport (GO:0015986) | 4.62642829 |
| 8 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.59822845 |
| 9 | rRNA modification (GO:0000154) | 4.34177436 |
| 10 | chaperone-mediated protein transport (GO:0072321) | 4.18174206 |
| 11 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.16554886 |
| 12 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.13447286 |
| 13 | rRNA methylation (GO:0031167) | 4.10370165 |
| 14 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.01240480 |
| 15 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.80252755 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.79567035 |
| 17 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.68674228 |
| 18 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.68674228 |
| 19 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.68674228 |
| 20 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.67570431 |
| 21 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.67570431 |
| 22 | behavioral response to nicotine (GO:0035095) | 3.64968605 |
| 23 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.62809465 |
| 24 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.58782022 |
| 25 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.57423807 |
| 26 | GTP biosynthetic process (GO:0006183) | 3.56858998 |
| 27 | protein complex biogenesis (GO:0070271) | 3.54907135 |
| 28 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.54827727 |
| 29 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.54827727 |
| 30 | negative regulation of ligase activity (GO:0051352) | 3.54001550 |
| 31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.54001550 |
| 32 | maturation of 5.8S rRNA (GO:0000460) | 3.52914114 |
| 33 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.51231218 |
| 34 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.36764039 |
| 35 | cullin deneddylation (GO:0010388) | 3.35932197 |
| 36 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.35166665 |
| 37 | fucose catabolic process (GO:0019317) | 3.32997044 |
| 38 | L-fucose metabolic process (GO:0042354) | 3.32997044 |
| 39 | L-fucose catabolic process (GO:0042355) | 3.32997044 |
| 40 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.31499978 |
| 41 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.31499978 |
| 42 | NADH dehydrogenase complex assembly (GO:0010257) | 3.31499978 |
| 43 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.28107851 |
| 44 | cytidine deamination (GO:0009972) | 3.27607865 |
| 45 | cytidine metabolic process (GO:0046087) | 3.27607865 |
| 46 | cytidine catabolic process (GO:0006216) | 3.27607865 |
| 47 | respiratory chain complex IV assembly (GO:0008535) | 3.26872799 |
| 48 | platelet dense granule organization (GO:0060155) | 3.23919786 |
| 49 | electron transport chain (GO:0022900) | 3.12091782 |
| 50 | respiratory electron transport chain (GO:0022904) | 3.10463769 |
| 51 | cellular ketone body metabolic process (GO:0046950) | 3.09571664 |
| 52 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.08714900 |
| 53 | positive regulation of ligase activity (GO:0051351) | 3.08013671 |
| 54 | protein deneddylation (GO:0000338) | 3.06888340 |
| 55 | UTP biosynthetic process (GO:0006228) | 3.06402299 |
| 56 | regulation of cellular amine metabolic process (GO:0033238) | 3.04107008 |
| 57 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.02709137 |
| 58 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.02709137 |
| 59 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.02590375 |
| 60 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.01021691 |
| 61 | DNA strand renaturation (GO:0000733) | 3.00952092 |
| 62 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.00635373 |
| 63 | DNA double-strand break processing (GO:0000729) | 3.00139839 |
| 64 | intracellular protein transmembrane import (GO:0044743) | 2.94767476 |
| 65 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.93454441 |
| 66 | protein polyglutamylation (GO:0018095) | 2.90485820 |
| 67 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.89025165 |
| 68 | ketone body metabolic process (GO:1902224) | 2.86165708 |
| 69 | UTP metabolic process (GO:0046051) | 2.85858607 |
| 70 | ATP biosynthetic process (GO:0006754) | 2.85452915 |
| 71 | pseudouridine synthesis (GO:0001522) | 2.85287086 |
| 72 | cytochrome complex assembly (GO:0017004) | 2.85243274 |
| 73 | positive regulation of prostaglandin secretion (GO:0032308) | 2.84949425 |
| 74 | signal peptide processing (GO:0006465) | 2.83114838 |
| 75 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.82342445 |
| 76 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.81467795 |
| 77 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.81266787 |
| 78 | positive regulation of cell cycle arrest (GO:0071158) | 2.79655447 |
| 79 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.78989431 |
| 80 | protein-cofactor linkage (GO:0018065) | 2.78301946 |
| 81 | aldehyde catabolic process (GO:0046185) | 2.73972805 |
| 82 | hydrogen ion transmembrane transport (GO:1902600) | 2.72676682 |
| 83 | replication fork processing (GO:0031297) | 2.71570240 |
| 84 | ribosome assembly (GO:0042255) | 2.71425701 |
| 85 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.69801836 |
| 86 | regulation of thymocyte apoptotic process (GO:0070243) | 2.68478461 |
| 87 | kynurenine metabolic process (GO:0070189) | 2.67562777 |
| 88 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.67384357 |
| 89 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.65979829 |
| 90 | protein K6-linked ubiquitination (GO:0085020) | 2.64676710 |
| 91 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.64201305 |
| 92 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.60783386 |
| 93 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.60696320 |
| 94 | rRNA catabolic process (GO:0016075) | 2.60479250 |
| 95 | recombinational repair (GO:0000725) | 2.58936032 |
| 96 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.58337978 |
| 97 | response to pheromone (GO:0019236) | 2.57405669 |
| 98 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.56528795 |
| 99 | ribosomal small subunit assembly (GO:0000028) | 2.56204148 |
| 100 | tRNA processing (GO:0008033) | 2.55781012 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.91813791 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.67091517 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.94137060 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.22306207 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.11548719 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.06320617 |
| 7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.98156615 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.85346948 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.71328070 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.69342361 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.65936758 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.62084094 |
| 13 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.53844365 |
| 14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.50156744 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.49083961 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.45809493 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.31466843 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.23655725 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.20603752 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.10513165 |
| 21 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.07225582 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 2.03420668 |
| 23 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.98445969 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97227422 |
| 25 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.97172244 |
| 26 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.80626467 |
| 27 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.79337248 |
| 28 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.62523205 |
| 29 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.61734589 |
| 30 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.60127401 |
| 31 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59759042 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.56376270 |
| 33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.53773723 |
| 34 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.52967071 |
| 35 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.48308490 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.48295954 |
| 37 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.46885938 |
| 38 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.46155559 |
| 39 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.44974531 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.42721248 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.42001511 |
| 42 | AR_20517297_ChIP-Seq_VCAP_Human | 1.41327038 |
| 43 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.37876393 |
| 44 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.36891832 |
| 45 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.34081232 |
| 46 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.34081232 |
| 47 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.33797889 |
| 48 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.33653724 |
| 49 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.33544474 |
| 50 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.32470423 |
| 51 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.30322997 |
| 52 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.30322997 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.28135820 |
| 54 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.27282067 |
| 55 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.24044680 |
| 56 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.17919438 |
| 57 | NCOR_22424771_ChIP-Seq_293T_Human | 1.17067809 |
| 58 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.14100711 |
| 59 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.13320102 |
| 60 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.11934639 |
| 61 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.11101390 |
| 62 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.10943361 |
| 63 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.08602217 |
| 64 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.08131074 |
| 65 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.07577958 |
| 66 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.07269456 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.05977423 |
| 68 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.04623284 |
| 69 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04396899 |
| 70 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.02539019 |
| 71 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.00457741 |
| 72 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.00361196 |
| 73 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.00212821 |
| 74 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.99186455 |
| 75 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98551843 |
| 76 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98420254 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.98395063 |
| 78 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.98026420 |
| 79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.97641796 |
| 80 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.97156750 |
| 81 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.95625776 |
| 82 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95024881 |
| 83 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.94605307 |
| 84 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.94327335 |
| 85 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94260568 |
| 86 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93170084 |
| 87 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92890194 |
| 88 | GATA3_26560356_Chip-Seq_TH2_Human | 0.92060204 |
| 89 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.91479249 |
| 90 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.89900218 |
| 91 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.88384452 |
| 92 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.88376139 |
| 93 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.88170207 |
| 94 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87149138 |
| 95 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.86805253 |
| 96 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.86647577 |
| 97 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.86384293 |
| 98 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.86097698 |
| 99 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.85842985 |
| 100 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.85066420 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 3.84423133 |
| 2 | MP0002102_abnormal_ear_morphology | 3.83486032 |
| 3 | MP0003195_calcinosis | 2.80169538 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.74173000 |
| 5 | MP0008872_abnormal_physiological_respon | 2.44415481 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.39005805 |
| 7 | MP0000372_irregular_coat_pigmentation | 2.35197622 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.29657120 |
| 9 | MP0004147_increased_porphyrin_level | 2.24865911 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.17674168 |
| 11 | MP0008058_abnormal_DNA_repair | 2.16301442 |
| 12 | MP0005075_abnormal_melanosome_morpholog | 2.12646781 |
| 13 | MP0004145_abnormal_muscle_electrophysio | 2.12583810 |
| 14 | MP0006036_abnormal_mitochondrial_physio | 2.09268019 |
| 15 | MP0002138_abnormal_hepatobiliary_system | 2.05188722 |
| 16 | MP0005671_abnormal_response_to | 2.00976374 |
| 17 | MP0005167_abnormal_blood-brain_barrier | 2.00750594 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 1.97932503 |
| 19 | MP0001835_abnormal_antigen_presentation | 1.93708684 |
| 20 | MP0003186_abnormal_redox_activity | 1.85483236 |
| 21 | MP0003718_maternal_effect | 1.79490469 |
| 22 | MP0003011_delayed_dark_adaptation | 1.73433859 |
| 23 | MP0008775_abnormal_heart_ventricle | 1.71697060 |
| 24 | MP0008007_abnormal_cellular_replicative | 1.68937948 |
| 25 | MP0003693_abnormal_embryo_hatching | 1.62937207 |
| 26 | MP0002938_white_spotting | 1.59920612 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.58288701 |
| 28 | MP0003786_premature_aging | 1.57912736 |
| 29 | MP0010094_abnormal_chromosome_stability | 1.51975679 |
| 30 | MP0001873_stomach_inflammation | 1.50865633 |
| 31 | MP0000685_abnormal_immune_system | 1.50615286 |
| 32 | MP0006035_abnormal_mitochondrial_morpho | 1.48275328 |
| 33 | MP0004142_abnormal_muscle_tone | 1.46448861 |
| 34 | MP0005646_abnormal_pituitary_gland | 1.41843602 |
| 35 | MP0002148_abnormal_hypersensitivity_rea | 1.38105551 |
| 36 | MP0002736_abnormal_nociception_after | 1.37803774 |
| 37 | MP0001986_abnormal_taste_sensitivity | 1.33709976 |
| 38 | MP0002272_abnormal_nervous_system | 1.32371314 |
| 39 | MP0003950_abnormal_plasma_membrane | 1.31639088 |
| 40 | MP0004215_abnormal_myocardial_fiber | 1.31391549 |
| 41 | MP0001968_abnormal_touch/_nociception | 1.31127354 |
| 42 | MP0005645_abnormal_hypothalamus_physiol | 1.28746494 |
| 43 | MP0001764_abnormal_homeostasis | 1.27365274 |
| 44 | MP0003283_abnormal_digestive_organ | 1.26177555 |
| 45 | MP0009764_decreased_sensitivity_to | 1.25458560 |
| 46 | MP0006292_abnormal_olfactory_placode | 1.24800292 |
| 47 | MP0006072_abnormal_retinal_apoptosis | 1.23281119 |
| 48 | MP0004885_abnormal_endolymph | 1.20808539 |
| 49 | MP0005389_reproductive_system_phenotype | 1.19961994 |
| 50 | MP0001485_abnormal_pinna_reflex | 1.17973542 |
| 51 | MP0001800_abnormal_humoral_immune | 1.08069100 |
| 52 | MP0001501_abnormal_sleep_pattern | 1.06623009 |
| 53 | MP0005408_hypopigmentation | 1.05047224 |
| 54 | MP0002234_abnormal_pharynx_morphology | 1.04374752 |
| 55 | MP0003567_abnormal_fetal_cardiomyocyte | 1.03603510 |
| 56 | MP0003638_abnormal_response/metabolism_ | 1.00386913 |
| 57 | MP0004957_abnormal_blastocyst_morpholog | 1.00232987 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.00179349 |
| 59 | MP0006276_abnormal_autonomic_nervous | 0.99766910 |
| 60 | MP0009333_abnormal_splenocyte_physiolog | 0.97853815 |
| 61 | MP0002653_abnormal_ependyma_morphology | 0.97489718 |
| 62 | MP0001919_abnormal_reproductive_system | 0.96860355 |
| 63 | MP0005332_abnormal_amino_acid | 0.96478458 |
| 64 | MP0009785_altered_susceptibility_to | 0.96300623 |
| 65 | MP0005083_abnormal_biliary_tract | 0.96120801 |
| 66 | MP0002160_abnormal_reproductive_system | 0.94085936 |
| 67 | MP0001881_abnormal_mammary_gland | 0.92374544 |
| 68 | MP0000427_abnormal_hair_cycle | 0.91352713 |
| 69 | MP0002006_tumorigenesis | 0.91143777 |
| 70 | MP0002095_abnormal_skin_pigmentation | 0.88161523 |
| 71 | MP0005253_abnormal_eye_physiology | 0.88022995 |
| 72 | MP0001663_abnormal_digestive_system | 0.85316381 |
| 73 | MP0005636_abnormal_mineral_homeostasis | 0.84696874 |
| 74 | MP0001790_abnormal_immune_system | 0.84530022 |
| 75 | MP0005387_immune_system_phenotype | 0.84530022 |
| 76 | MP0002733_abnormal_thermal_nociception | 0.82420158 |
| 77 | MP0004742_abnormal_vestibular_system | 0.82359545 |
| 78 | MP0001984_abnormal_olfaction | 0.80573968 |
| 79 | MP0008789_abnormal_olfactory_epithelium | 0.78999862 |
| 80 | MP0002090_abnormal_vision | 0.78874156 |
| 81 | MP0005410_abnormal_fertilization | 0.78736362 |
| 82 | MP0000383_abnormal_hair_follicle | 0.77626562 |
| 83 | MP0002166_altered_tumor_susceptibility | 0.76507233 |
| 84 | MP0004381_abnormal_hair_follicle | 0.75436677 |
| 85 | MP0009745_abnormal_behavioral_response | 0.75418426 |
| 86 | MP0001929_abnormal_gametogenesis | 0.75257074 |
| 87 | MP0010386_abnormal_urinary_bladder | 0.74626402 |
| 88 | MP0005464_abnormal_platelet_physiology | 0.73891622 |
| 89 | MP0001970_abnormal_pain_threshold | 0.73051217 |
| 90 | MP0000569_abnormal_digit_pigmentation | 0.72351313 |
| 91 | MP0000358_abnormal_cell_content/ | 0.72268257 |
| 92 | MP0005000_abnormal_immune_tolerance | 0.71912866 |
| 93 | MP0000613_abnormal_salivary_gland | 0.71585322 |
| 94 | MP0000230_abnormal_systemic_arterial | 0.70524797 |
| 95 | MP0009046_muscle_twitch | 0.69821272 |
| 96 | MP0001905_abnormal_dopamine_level | 0.69800975 |
| 97 | MP0001879_abnormal_lymphatic_vessel | 0.69541522 |
| 98 | MP0001765_abnormal_ion_homeostasis | 0.68451123 |
| 99 | MP0004782_abnormal_surfactant_physiolog | 0.68352671 |
| 100 | MP0002210_abnormal_sex_determination | 0.68150287 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hepatocellular necrosis (HP:0001404) | 4.36312631 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.21467319 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.12598776 |
| 4 | Hepatic necrosis (HP:0002605) | 4.12008282 |
| 5 | Increased CSF lactate (HP:0002490) | 4.11681403 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.81315021 |
| 7 | Acute encephalopathy (HP:0006846) | 3.70737931 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.48650700 |
| 9 | Increased serum lactate (HP:0002151) | 3.20548683 |
| 10 | Abnormality of alanine metabolism (HP:0010916) | 3.09729288 |
| 11 | Hyperalaninemia (HP:0003348) | 3.09729288 |
| 12 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.09729288 |
| 13 | Abnormality of B cell number (HP:0010975) | 3.02284637 |
| 14 | Optic disc pallor (HP:0000543) | 2.99814461 |
| 15 | 3-Methylglutaconic aciduria (HP:0003535) | 2.97571745 |
| 16 | Pancreatic cysts (HP:0001737) | 2.96595078 |
| 17 | Congenital stationary night blindness (HP:0007642) | 2.96441924 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 2.95336132 |
| 19 | Cerebral edema (HP:0002181) | 2.93219822 |
| 20 | Dyschromatopsia (HP:0007641) | 2.88271150 |
| 21 | Increased serum pyruvate (HP:0003542) | 2.83164918 |
| 22 | B lymphocytopenia (HP:0010976) | 2.82557752 |
| 23 | Lipid accumulation in hepatocytes (HP:0006561) | 2.77318676 |
| 24 | Molar tooth sign on MRI (HP:0002419) | 2.75200421 |
| 25 | Abnormality of midbrain morphology (HP:0002418) | 2.75200421 |
| 26 | IgG deficiency (HP:0004315) | 2.67886313 |
| 27 | Abnormality of glycolysis (HP:0004366) | 2.54601679 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.53346705 |
| 29 | Abolished electroretinogram (ERG) (HP:0000550) | 2.50042082 |
| 30 | Hypoproteinemia (HP:0003075) | 2.48088450 |
| 31 | CNS demyelination (HP:0007305) | 2.44779763 |
| 32 | True hermaphroditism (HP:0010459) | 2.44036335 |
| 33 | Methylmalonic aciduria (HP:0012120) | 2.43921617 |
| 34 | Constricted visual fields (HP:0001133) | 2.43554274 |
| 35 | Methylmalonic acidemia (HP:0002912) | 2.43066484 |
| 36 | Parakeratosis (HP:0001036) | 2.41166264 |
| 37 | Respiratory failure (HP:0002878) | 2.39898278 |
| 38 | Abnormality of the pons (HP:0007361) | 2.36819874 |
| 39 | Lactic acidosis (HP:0003128) | 2.35820779 |
| 40 | Abnormality of the labia minora (HP:0012880) | 2.32496190 |
| 41 | Type I transferrin isoform profile (HP:0003642) | 2.30945573 |
| 42 | Renal Fanconi syndrome (HP:0001994) | 2.29996819 |
| 43 | Degeneration of anterior horn cells (HP:0002398) | 2.29721421 |
| 44 | Abnormality of the anterior horn cell (HP:0006802) | 2.29721421 |
| 45 | Stomatitis (HP:0010280) | 2.24132530 |
| 46 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.23802122 |
| 47 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.23802122 |
| 48 | Colon cancer (HP:0003003) | 2.23442228 |
| 49 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.22763495 |
| 50 | Nephronophthisis (HP:0000090) | 2.21590148 |
| 51 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.21542883 |
| 52 | Pendular nystagmus (HP:0012043) | 2.19310211 |
| 53 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.15925062 |
| 54 | Absent/shortened dynein arms (HP:0200106) | 2.15925062 |
| 55 | Abnormal protein glycosylation (HP:0012346) | 2.15004693 |
| 56 | Abnormal glycosylation (HP:0012345) | 2.15004693 |
| 57 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.15004693 |
| 58 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.15004693 |
| 59 | Lethargy (HP:0001254) | 2.13152927 |
| 60 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.11804957 |
| 61 | Attenuation of retinal blood vessels (HP:0007843) | 2.11556750 |
| 62 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.11519182 |
| 63 | Abnormality of serum amino acid levels (HP:0003112) | 2.09500447 |
| 64 | Central scotoma (HP:0000603) | 2.06826624 |
| 65 | Exertional dyspnea (HP:0002875) | 2.04893759 |
| 66 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.04520431 |
| 67 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.04520431 |
| 68 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.02484081 |
| 69 | Abnormality of the renal cortex (HP:0011035) | 2.01792969 |
| 70 | Hypomagnesemia (HP:0002917) | 2.00724070 |
| 71 | IgA deficiency (HP:0002720) | 1.96696844 |
| 72 | Exercise intolerance (HP:0003546) | 1.96319422 |
| 73 | Keratoconus (HP:0000563) | 1.95988878 |
| 74 | Increased corneal curvature (HP:0100692) | 1.95988878 |
| 75 | Congenital, generalized hypertrichosis (HP:0004540) | 1.95774381 |
| 76 | Severe combined immunodeficiency (HP:0004430) | 1.95219384 |
| 77 | Hypoplasia of the pons (HP:0012110) | 1.94673463 |
| 78 | Abnormality of the renal medulla (HP:0100957) | 1.94016365 |
| 79 | Increased intramyocellular lipid droplets (HP:0012240) | 1.93906463 |
| 80 | Tubular atrophy (HP:0000092) | 1.93887736 |
| 81 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.92703128 |
| 82 | Adactyly (HP:0009776) | 1.89929422 |
| 83 | Hypoplasia of the uterus (HP:0000013) | 1.89358854 |
| 84 | Chronic sinusitis (HP:0011109) | 1.88948187 |
| 85 | Decreased central vision (HP:0007663) | 1.85668326 |
| 86 | Supernumerary spleens (HP:0009799) | 1.84034435 |
| 87 | Abnormal drinking behavior (HP:0030082) | 1.80714096 |
| 88 | Polydipsia (HP:0001959) | 1.80714096 |
| 89 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.80324387 |
| 90 | Leukodystrophy (HP:0002415) | 1.78662710 |
| 91 | Hyperglycinemia (HP:0002154) | 1.78251792 |
| 92 | Prostate neoplasm (HP:0100787) | 1.77235878 |
| 93 | Thyroiditis (HP:0100646) | 1.77082939 |
| 94 | Inability to walk (HP:0002540) | 1.75461272 |
| 95 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.74841811 |
| 96 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.73579872 |
| 97 | Abnormal ciliary motility (HP:0012262) | 1.73153801 |
| 98 | Abnormality of magnesium homeostasis (HP:0004921) | 1.72637945 |
| 99 | Abnormality of methionine metabolism (HP:0010901) | 1.71444214 |
| 100 | Polyuria (HP:0000103) | 1.71069534 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.86658303 |
| 2 | NUAK1 | 3.61351583 |
| 3 | MST4 | 3.35755151 |
| 4 | TIE1 | 3.33398355 |
| 5 | EIF2AK3 | 2.95111557 |
| 6 | TAF1 | 2.67580552 |
| 7 | TSSK6 | 2.42906407 |
| 8 | FRK | 2.39174687 |
| 9 | MAP3K12 | 2.32543911 |
| 10 | GRK1 | 2.21764977 |
| 11 | VRK1 | 2.18350283 |
| 12 | BMPR1B | 2.15446990 |
| 13 | BUB1 | 2.14838625 |
| 14 | TRIM28 | 2.13366413 |
| 15 | STK39 | 1.89613715 |
| 16 | PLK3 | 1.72249654 |
| 17 | OXSR1 | 1.69154026 |
| 18 | TAOK3 | 1.67111228 |
| 19 | EIF2AK1 | 1.66663562 |
| 20 | ADRBK2 | 1.66498451 |
| 21 | ZAK | 1.59198978 |
| 22 | PDK2 | 1.57643292 |
| 23 | TLK1 | 1.53830228 |
| 24 | PLK2 | 1.50003411 |
| 25 | DAPK1 | 1.48737521 |
| 26 | WNK4 | 1.44988367 |
| 27 | NEK1 | 1.42271137 |
| 28 | TXK | 1.38521457 |
| 29 | TGFBR1 | 1.26952983 |
| 30 | STK16 | 1.25257123 |
| 31 | GRK5 | 1.17898120 |
| 32 | DYRK2 | 1.15868921 |
| 33 | MYLK | 1.15312486 |
| 34 | PLK4 | 1.14159144 |
| 35 | NME1 | 1.13895221 |
| 36 | CSNK1G1 | 1.13806431 |
| 37 | CCNB1 | 1.13718515 |
| 38 | EIF2AK2 | 1.13584383 |
| 39 | MAP3K9 | 1.09635968 |
| 40 | TEC | 1.08039953 |
| 41 | CSNK1G3 | 1.07951859 |
| 42 | WNK3 | 0.96656271 |
| 43 | CDK8 | 0.91693730 |
| 44 | MAP4K2 | 0.91469185 |
| 45 | CSNK1A1L | 0.90150427 |
| 46 | CSNK1G2 | 0.85977074 |
| 47 | IKBKB | 0.85647566 |
| 48 | ARAF | 0.85130977 |
| 49 | SRPK1 | 0.84413863 |
| 50 | BCKDK | 0.84014055 |
| 51 | MAPKAPK3 | 0.83975732 |
| 52 | SMG1 | 0.83655823 |
| 53 | ACVR1B | 0.81332265 |
| 54 | PBK | 0.80578289 |
| 55 | MAPKAPK5 | 0.79072929 |
| 56 | PHKG2 | 0.78012026 |
| 57 | PHKG1 | 0.78012026 |
| 58 | ILK | 0.76229438 |
| 59 | LIMK1 | 0.73718675 |
| 60 | SIK3 | 0.70406649 |
| 61 | PINK1 | 0.68894121 |
| 62 | PIK3CG | 0.67155544 |
| 63 | ADRBK1 | 0.64974612 |
| 64 | DAPK3 | 0.62321934 |
| 65 | PRKCI | 0.61866663 |
| 66 | MKNK1 | 0.60565765 |
| 67 | INSRR | 0.58198417 |
| 68 | PTK2B | 0.56683679 |
| 69 | DAPK2 | 0.54347684 |
| 70 | KIT | 0.54133954 |
| 71 | PLK1 | 0.53179977 |
| 72 | STK3 | 0.52981214 |
| 73 | IRAK1 | 0.51928936 |
| 74 | SYK | 0.50630788 |
| 75 | PRKCQ | 0.48211824 |
| 76 | MKNK2 | 0.46977939 |
| 77 | STK24 | 0.46772388 |
| 78 | SCYL2 | 0.44552080 |
| 79 | FLT3 | 0.43702853 |
| 80 | BCR | 0.42787263 |
| 81 | ATR | 0.41716831 |
| 82 | PASK | 0.41520155 |
| 83 | STK38L | 0.41335450 |
| 84 | MAPK13 | 0.39295895 |
| 85 | PRKCE | 0.37283804 |
| 86 | MINK1 | 0.36377433 |
| 87 | PRKCG | 0.36056448 |
| 88 | NLK | 0.35713083 |
| 89 | KDR | 0.34078430 |
| 90 | FER | 0.34023176 |
| 91 | GRK6 | 0.33374814 |
| 92 | STK4 | 0.31470672 |
| 93 | CDC7 | 0.30593827 |
| 94 | ERBB3 | 0.30036478 |
| 95 | MAP3K13 | 0.28785967 |
| 96 | OBSCN | 0.27475907 |
| 97 | CAMK2A | 0.25349464 |
| 98 | CSNK1A1 | 0.23662298 |
| 99 | ITK | 0.23323471 |
| 100 | BMPR2 | 0.22877480 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.25596755 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.21880726 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.77770402 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.71523972 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.36124784 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.16019859 |
| 7 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.97389878 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.96539047 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.89180374 |
| 10 | Asthma_Homo sapiens_hsa05310 | 1.88382074 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 1.84452939 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 1.83434193 |
| 13 | RNA degradation_Homo sapiens_hsa03018 | 1.80145409 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.75355374 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.74093434 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.70242996 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.69191144 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.67040816 |
| 19 | Ribosome_Homo sapiens_hsa03010 | 1.64277987 |
| 20 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.63225271 |
| 21 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.62476347 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.59262188 |
| 23 | Allograft rejection_Homo sapiens_hsa05330 | 1.50365318 |
| 24 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.46012121 |
| 25 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.39424992 |
| 26 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.35809394 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.33939472 |
| 28 | Phototransduction_Homo sapiens_hsa04744 | 1.30631501 |
| 29 | Peroxisome_Homo sapiens_hsa04146 | 1.29600752 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.29591980 |
| 31 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.29585193 |
| 32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.29053404 |
| 33 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.26342041 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26242184 |
| 35 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.24460897 |
| 36 | RNA transport_Homo sapiens_hsa03013 | 1.23748060 |
| 37 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.23398660 |
| 38 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.23235495 |
| 39 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.19624850 |
| 40 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.18837005 |
| 41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.18197867 |
| 42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.18057004 |
| 43 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.15260322 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 1.10369012 |
| 45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.09601301 |
| 46 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.09144302 |
| 47 | DNA replication_Homo sapiens_hsa03030 | 1.09060027 |
| 48 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.08598075 |
| 49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.08549944 |
| 50 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.06058364 |
| 51 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.05286160 |
| 52 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.04265788 |
| 53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.04168819 |
| 54 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.99322038 |
| 55 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.99171380 |
| 56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.99081074 |
| 57 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.95033831 |
| 58 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.87951678 |
| 59 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.86983247 |
| 60 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.84013499 |
| 61 | Base excision repair_Homo sapiens_hsa03410 | 0.82578028 |
| 62 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.82526479 |
| 63 | Spliceosome_Homo sapiens_hsa03040 | 0.75679402 |
| 64 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.75676633 |
| 65 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.75167129 |
| 66 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.74829134 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.73803812 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71694931 |
| 69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.70882168 |
| 70 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70103599 |
| 71 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.66821104 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.66296018 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65803232 |
| 74 | Carbon metabolism_Homo sapiens_hsa01200 | 0.64155732 |
| 75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.62333069 |
| 76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.61152531 |
| 77 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.61017026 |
| 78 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.58876285 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58739343 |
| 80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58273049 |
| 81 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.57923571 |
| 82 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.55751661 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.53858804 |
| 84 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.50026626 |
| 85 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.49324237 |
| 86 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.48576755 |
| 87 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.45228173 |
| 88 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.43738716 |
| 89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42742802 |
| 90 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.41152047 |
| 91 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40844637 |
| 92 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.40832696 |
| 93 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.40596426 |
| 94 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.38639653 |
| 95 | Nicotine addiction_Homo sapiens_hsa05033 | 0.36852982 |
| 96 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.35809378 |
| 97 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.35575849 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.34962432 |
| 99 | Retinol metabolism_Homo sapiens_hsa00830 | 0.33732925 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.33682440 |

