

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | eosinophil chemotaxis (GO:0048245) | 8.54531067 |
| 2 | prenylation (GO:0097354) | 8.09579446 |
| 3 | protein prenylation (GO:0018342) | 8.09579446 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 7.78941652 |
| 5 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 7.77237101 |
| 6 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 7.77237101 |
| 7 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 7.77237101 |
| 8 | eosinophil migration (GO:0072677) | 7.70012037 |
| 9 | negative regulation of Ras GTPase activity (GO:0034261) | 7.13028626 |
| 10 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 6.81654953 |
| 11 | L-fucose catabolic process (GO:0042355) | 6.08927349 |
| 12 | fucose catabolic process (GO:0019317) | 6.08927349 |
| 13 | L-fucose metabolic process (GO:0042354) | 6.08927349 |
| 14 | regulation of mononuclear cell migration (GO:0071675) | 6.06857410 |
| 15 | proteasome assembly (GO:0043248) | 5.76318043 |
| 16 | regulation of sister chromatid cohesion (GO:0007063) | 5.45189145 |
| 17 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 5.43028622 |
| 18 | macrophage chemotaxis (GO:0048246) | 5.24859409 |
| 19 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 5.22205887 |
| 20 | cytidine deamination (GO:0009972) | 5.18385258 |
| 21 | cytidine metabolic process (GO:0046087) | 5.18385258 |
| 22 | cytidine catabolic process (GO:0006216) | 5.18385258 |
| 23 | DNA deamination (GO:0045006) | 5.09395156 |
| 24 | positive regulation of chromosome segregation (GO:0051984) | 5.06774417 |
| 25 | branch elongation of an epithelium (GO:0060602) | 4.81366153 |
| 26 | vesicle fusion (GO:0006906) | 4.67186417 |
| 27 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 4.66873386 |
| 28 | coenzyme A biosynthetic process (GO:0015937) | 4.64914148 |
| 29 | autophagic vacuole fusion (GO:0000046) | 4.61507447 |
| 30 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.56073092 |
| 31 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.36334410 |
| 32 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.10353284 |
| 33 | localization within membrane (GO:0051668) | 4.09092463 |
| 34 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.09010817 |
| 35 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.05741015 |
| 36 | ATP synthesis coupled proton transport (GO:0015986) | 4.05741015 |
| 37 | organelle membrane fusion (GO:0090174) | 3.91795718 |
| 38 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.90818655 |
| 39 | monocyte chemotaxis (GO:0002548) | 3.88585328 |
| 40 | positive regulation of calcium ion import (GO:0090280) | 3.85401253 |
| 41 | DNA demethylation (GO:0080111) | 3.81754970 |
| 42 | non-recombinational repair (GO:0000726) | 3.78914230 |
| 43 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.78914230 |
| 44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.78063104 |
| 45 | positive chemotaxis (GO:0050918) | 3.77911526 |
| 46 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.75787791 |
| 47 | organ growth (GO:0035265) | 3.72835834 |
| 48 | oxidative demethylation (GO:0070989) | 3.70131646 |
| 49 | protein import into peroxisome matrix (GO:0016558) | 3.69462425 |
| 50 | iron-sulfur cluster assembly (GO:0016226) | 3.64114789 |
| 51 | metallo-sulfur cluster assembly (GO:0031163) | 3.64114789 |
| 52 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.60606512 |
| 53 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.59469798 |
| 54 | NADH dehydrogenase complex assembly (GO:0010257) | 3.59469798 |
| 55 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.59469798 |
| 56 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.58310502 |
| 57 | chaperone-mediated protein transport (GO:0072321) | 3.53188825 |
| 58 | termination of RNA polymerase III transcription (GO:0006386) | 3.52772954 |
| 59 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.52772954 |
| 60 | protein complex biogenesis (GO:0070271) | 3.48950146 |
| 61 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.48814891 |
| 62 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.48814891 |
| 63 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.46866474 |
| 64 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.46866474 |
| 65 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.46866474 |
| 66 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.43219289 |
| 67 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.43219289 |
| 68 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.40669623 |
| 69 | pantothenate metabolic process (GO:0015939) | 3.39636967 |
| 70 | DNA integration (GO:0015074) | 3.38738818 |
| 71 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.38468591 |
| 72 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 3.36857845 |
| 73 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.27544404 |
| 74 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.27390389 |
| 75 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.24498908 |
| 76 | DNA dealkylation (GO:0035510) | 3.24314452 |
| 77 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.23973221 |
| 78 | protein neddylation (GO:0045116) | 3.21773325 |
| 79 | regulation of autophagic vacuole assembly (GO:2000785) | 3.20772665 |
| 80 | peptidyl-lysine dimethylation (GO:0018027) | 3.17623308 |
| 81 | seminiferous tubule development (GO:0072520) | 3.16418217 |
| 82 | respiratory electron transport chain (GO:0022904) | 3.14375765 |
| 83 | negative regulation of ligase activity (GO:0051352) | 3.14246128 |
| 84 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.14246128 |
| 85 | GPI anchor biosynthetic process (GO:0006506) | 3.11566789 |
| 86 | electron transport chain (GO:0022900) | 3.08797004 |
| 87 | fucosylation (GO:0036065) | 3.07881634 |
| 88 | axis elongation (GO:0003401) | 3.07327995 |
| 89 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.05011142 |
| 90 | intracellular protein transmembrane import (GO:0044743) | 3.04853069 |
| 91 | regulation of T cell apoptotic process (GO:0070232) | 2.98748598 |
| 92 | organelle fusion (GO:0048284) | 2.96258474 |
| 93 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.95593007 |
| 94 | membrane budding (GO:0006900) | 2.89528999 |
| 95 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.86110478 |
| 96 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.84268967 |
| 97 | fucose metabolic process (GO:0006004) | 2.84088938 |
| 98 | regulation of beta-amyloid formation (GO:1902003) | 2.83230417 |
| 99 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.83146221 |
| 100 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.83146221 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.71003508 |
| 2 | GATA1_22025678_ChIP-Seq_K562_Human | 5.95245150 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 5.02699848 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.70088661 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.96688826 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.51964779 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.14708599 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.89737401 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.88969269 |
| 10 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.87650557 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.72795929 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.67935011 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.65302258 |
| 14 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.61483074 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.59238523 |
| 16 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.58654255 |
| 17 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.41002751 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.30517249 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.16626306 |
| 20 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.09286981 |
| 21 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 2.03676991 |
| 22 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.95459424 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.90235722 |
| 24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.86972860 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.85152548 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.76596508 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.70961897 |
| 28 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.69244440 |
| 29 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.69148276 |
| 30 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.66969473 |
| 31 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.66058733 |
| 32 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.57071826 |
| 33 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.56256498 |
| 34 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.53588581 |
| 35 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.53431756 |
| 36 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.51481358 |
| 37 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48968187 |
| 38 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.47810589 |
| 39 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.44798672 |
| 40 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.38382298 |
| 41 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.37212622 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.28092881 |
| 43 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.25979635 |
| 44 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.23714692 |
| 45 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.23705783 |
| 46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.21997587 |
| 47 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.20013351 |
| 48 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.19329954 |
| 49 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.18460466 |
| 50 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.17205143 |
| 51 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.16828202 |
| 52 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.13431446 |
| 53 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.11485894 |
| 54 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.10889005 |
| 55 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.10107991 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08854182 |
| 57 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.06650227 |
| 58 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.04257404 |
| 59 | RXR_22108803_ChIP-Seq_LS180_Human | 1.02040595 |
| 60 | FUS_26573619_Chip-Seq_HEK293_Human | 1.01918335 |
| 61 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.01300443 |
| 62 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.01300443 |
| 63 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99665324 |
| 64 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.99160328 |
| 65 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.99124046 |
| 66 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.98544623 |
| 67 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.96285671 |
| 68 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.94904915 |
| 69 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.93616492 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.92097026 |
| 71 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.91307962 |
| 72 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.91286689 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.90019453 |
| 74 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.89600862 |
| 75 | GATA3_26560356_Chip-Seq_TH1_Human | 0.89424894 |
| 76 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.86933136 |
| 77 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.86748986 |
| 78 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.85007456 |
| 79 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.84866466 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.84619589 |
| 81 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.84619589 |
| 82 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.83665262 |
| 83 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.82673971 |
| 84 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.82200311 |
| 85 | P300_19829295_ChIP-Seq_ESCs_Human | 0.82130500 |
| 86 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.81564273 |
| 87 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.79501689 |
| 88 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.79002689 |
| 89 | AR_20517297_ChIP-Seq_VCAP_Human | 0.78055998 |
| 90 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.77015827 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.76769822 |
| 92 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.76425052 |
| 93 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.75276606 |
| 94 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.74462501 |
| 95 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.74233645 |
| 96 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.74194648 |
| 97 | NCOR_22424771_ChIP-Seq_293T_Human | 0.73324417 |
| 98 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.73091942 |
| 99 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.72890407 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.72715931 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 9.03538616 |
| 2 | MP0003303_peritoneal_inflammation | 5.48432551 |
| 3 | MP0006082_CNS_inflammation | 4.16065899 |
| 4 | MP0005671_abnormal_response_to | 2.81131943 |
| 5 | MP0001919_abnormal_reproductive_system | 2.51226370 |
| 6 | MP0001663_abnormal_digestive_system | 2.41008881 |
| 7 | MP0001664_abnormal_digestion | 2.39024884 |
| 8 | MP0002876_abnormal_thyroid_physiology | 2.33332856 |
| 9 | MP0002751_abnormal_autonomic_nervous | 2.10965466 |
| 10 | MP0004145_abnormal_muscle_electrophysio | 2.07496414 |
| 11 | MP0002138_abnormal_hepatobiliary_system | 2.06475155 |
| 12 | MP0005389_reproductive_system_phenotype | 2.05305627 |
| 13 | MP0000467_abnormal_esophagus_morphology | 1.99828923 |
| 14 | MP0002102_abnormal_ear_morphology | 1.85070373 |
| 15 | MP0005381_digestive/alimentary_phenotyp | 1.76269892 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 1.74436153 |
| 17 | MP0005166_decreased_susceptibility_to | 1.61891079 |
| 18 | MP0001905_abnormal_dopamine_level | 1.55584809 |
| 19 | MP0003937_abnormal_limbs/digits/tail_de | 1.45460683 |
| 20 | MP0001764_abnormal_homeostasis | 1.37436442 |
| 21 | MP0005360_urolithiasis | 1.33165272 |
| 22 | MP0008872_abnormal_physiological_respon | 1.31296680 |
| 23 | MP0006072_abnormal_retinal_apoptosis | 1.31259407 |
| 24 | MP0001968_abnormal_touch/_nociception | 1.28638887 |
| 25 | MP0001529_abnormal_vocalization | 1.27874139 |
| 26 | MP0002736_abnormal_nociception_after | 1.27087981 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.25767279 |
| 28 | MP0003806_abnormal_nucleotide_metabolis | 1.25263513 |
| 29 | MP0003763_abnormal_thymus_physiology | 1.25057846 |
| 30 | MP0009785_altered_susceptibility_to | 1.24473187 |
| 31 | MP0010155_abnormal_intestine_physiology | 1.23558204 |
| 32 | MP0001293_anophthalmia | 1.23310355 |
| 33 | MP0008875_abnormal_xenobiotic_pharmacok | 1.22878273 |
| 34 | MP0000685_abnormal_immune_system | 1.18438629 |
| 35 | MP0005085_abnormal_gallbladder_physiolo | 1.17466200 |
| 36 | MP0003115_abnormal_respiratory_system | 1.16371172 |
| 37 | MP0000490_abnormal_crypts_of | 1.11748347 |
| 38 | MP0000383_abnormal_hair_follicle | 1.11047890 |
| 39 | MP0005253_abnormal_eye_physiology | 1.08906427 |
| 40 | MP0000534_abnormal_ureter_morphology | 1.08621511 |
| 41 | MP0005083_abnormal_biliary_tract | 1.07263098 |
| 42 | MP0009333_abnormal_splenocyte_physiolog | 1.04401785 |
| 43 | MP0003638_abnormal_response/metabolism_ | 1.03728238 |
| 44 | MP0005084_abnormal_gallbladder_morpholo | 1.03094108 |
| 45 | MP0002139_abnormal_hepatobiliary_system | 1.02811822 |
| 46 | MP0002837_dystrophic_cardiac_calcinosis | 1.02004900 |
| 47 | MP0002163_abnormal_gland_morphology | 1.01118998 |
| 48 | MP0009379_abnormal_foot_pigmentation | 0.95565665 |
| 49 | MP0002277_abnormal_respiratory_mucosa | 0.95474074 |
| 50 | MP0004019_abnormal_vitamin_homeostasis | 0.94894688 |
| 51 | MP0001835_abnormal_antigen_presentation | 0.93845398 |
| 52 | MP0003718_maternal_effect | 0.93303682 |
| 53 | MP0008058_abnormal_DNA_repair | 0.92438086 |
| 54 | MP0001963_abnormal_hearing_physiology | 0.91602883 |
| 55 | MP0002166_altered_tumor_susceptibility | 0.91511205 |
| 56 | MP0002006_tumorigenesis | 0.90820585 |
| 57 | MP0002019_abnormal_tumor_incidence | 0.89723027 |
| 58 | MP0001485_abnormal_pinna_reflex | 0.89669061 |
| 59 | MP0000026_abnormal_inner_ear | 0.87719350 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 0.87669568 |
| 61 | MP0003878_abnormal_ear_physiology | 0.87669568 |
| 62 | MP0002210_abnormal_sex_determination | 0.87022690 |
| 63 | MP0004147_increased_porphyrin_level | 0.86896783 |
| 64 | MP0002938_white_spotting | 0.85137745 |
| 65 | MP0006292_abnormal_olfactory_placode | 0.84479150 |
| 66 | MP0009697_abnormal_copulation | 0.83942771 |
| 67 | MP0004142_abnormal_muscle_tone | 0.83081638 |
| 68 | MP0003252_abnormal_bile_duct | 0.81469417 |
| 69 | MP0000477_abnormal_intestine_morphology | 0.81315865 |
| 70 | MP0002160_abnormal_reproductive_system | 0.81232951 |
| 71 | MP0003959_abnormal_lean_body | 0.80869964 |
| 72 | MP0005332_abnormal_amino_acid | 0.80628587 |
| 73 | MP0004885_abnormal_endolymph | 0.80496657 |
| 74 | MP0001800_abnormal_humoral_immune | 0.79260025 |
| 75 | MP0009763_increased_sensitivity_to | 0.77844691 |
| 76 | MP0001790_abnormal_immune_system | 0.77474157 |
| 77 | MP0005387_immune_system_phenotype | 0.77474157 |
| 78 | MP0002109_abnormal_limb_morphology | 0.75764126 |
| 79 | MP0006276_abnormal_autonomic_nervous | 0.75671888 |
| 80 | MP0001501_abnormal_sleep_pattern | 0.75155018 |
| 81 | MP0005025_abnormal_response_to | 0.74819150 |
| 82 | MP0002148_abnormal_hypersensitivity_rea | 0.74587057 |
| 83 | MP0009745_abnormal_behavioral_response | 0.71271078 |
| 84 | MP0003866_abnormal_defecation | 0.70414288 |
| 85 | MP0000049_abnormal_middle_ear | 0.69915703 |
| 86 | MP0000358_abnormal_cell_content/ | 0.69630679 |
| 87 | MP0001119_abnormal_female_reproductive | 0.68074096 |
| 88 | MP0002735_abnormal_chemical_nociception | 0.67261412 |
| 89 | MP0009764_decreased_sensitivity_to | 0.67001756 |
| 90 | MP0003786_premature_aging | 0.66224987 |
| 91 | MP0002115_abnormal_skeleton_extremities | 0.65850850 |
| 92 | MP0003646_muscle_fatigue | 0.65073192 |
| 93 | MP0009643_abnormal_urine_homeostasis | 0.64495647 |
| 94 | MP0002733_abnormal_thermal_nociception | 0.63560217 |
| 95 | MP0005000_abnormal_immune_tolerance | 0.62838430 |
| 96 | MP0002272_abnormal_nervous_system | 0.61791731 |
| 97 | MP0005551_abnormal_eye_electrophysiolog | 0.59900218 |
| 98 | MP0006036_abnormal_mitochondrial_physio | 0.59085192 |
| 99 | MP0001286_abnormal_eye_development | 0.58833799 |
| 100 | MP0002420_abnormal_adaptive_immunity | 0.58619093 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 7.16718386 |
| 2 | Duplicated collecting system (HP:0000081) | 5.48702367 |
| 3 | Abnormality of the renal collecting system (HP:0004742) | 5.22748791 |
| 4 | Abnormality of fatty-acid metabolism (HP:0004359) | 4.58771884 |
| 5 | Large for gestational age (HP:0001520) | 4.39513832 |
| 6 | Adactyly (HP:0009776) | 4.29424770 |
| 7 | Long foot (HP:0001833) | 4.23176524 |
| 8 | Hypoplastic pelvis (HP:0008839) | 4.22505182 |
| 9 | Dry hair (HP:0011359) | 4.15826875 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 4.03060210 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.99616540 |
| 12 | Reduced subcutaneous adipose tissue (HP:0003758) | 3.71459489 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.70599182 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.63221802 |
| 15 | Hepatic necrosis (HP:0002605) | 3.52382535 |
| 16 | Acute encephalopathy (HP:0006846) | 3.51166420 |
| 17 | Progressive muscle weakness (HP:0003323) | 3.49207017 |
| 18 | Increased CSF lactate (HP:0002490) | 3.42157914 |
| 19 | Progressive macrocephaly (HP:0004481) | 3.35003665 |
| 20 | Lactic acidosis (HP:0003128) | 3.34731857 |
| 21 | Brushfield spots (HP:0001088) | 3.24324860 |
| 22 | Menstrual irregularities (HP:0000858) | 3.17552157 |
| 23 | Ureteral duplication (HP:0000073) | 3.16387239 |
| 24 | Ureteral stenosis (HP:0000071) | 3.13122227 |
| 25 | Steatorrhea (HP:0002570) | 2.99595761 |
| 26 | Acute lymphatic leukemia (HP:0006721) | 2.97408277 |
| 27 | Broad-based gait (HP:0002136) | 2.96017806 |
| 28 | Severe muscular hypotonia (HP:0006829) | 2.90875729 |
| 29 | Increased serum lactate (HP:0002151) | 2.82389654 |
| 30 | 3-Methylglutaconic aciduria (HP:0003535) | 2.80915764 |
| 31 | Ureteral obstruction (HP:0006000) | 2.79667238 |
| 32 | Increased hepatocellular lipid droplets (HP:0006565) | 2.72732710 |
| 33 | Renal Fanconi syndrome (HP:0001994) | 2.72217068 |
| 34 | Rhabdomyolysis (HP:0003201) | 2.71244932 |
| 35 | Cerebral edema (HP:0002181) | 2.68959975 |
| 36 | Respiratory failure (HP:0002878) | 2.68107378 |
| 37 | Autoamputation (HP:0001218) | 2.63447819 |
| 38 | Myoglobinuria (HP:0002913) | 2.62942906 |
| 39 | Lipid accumulation in hepatocytes (HP:0006561) | 2.61721088 |
| 40 | Pulmonary artery stenosis (HP:0004415) | 2.61654960 |
| 41 | Exercise intolerance (HP:0003546) | 2.59101383 |
| 42 | Fat malabsorption (HP:0002630) | 2.56061292 |
| 43 | Oral leukoplakia (HP:0002745) | 2.48821391 |
| 44 | CNS demyelination (HP:0007305) | 2.46558050 |
| 45 | Decreased lacrimation (HP:0000633) | 2.38359776 |
| 46 | Anhidrosis (HP:0000970) | 2.38087238 |
| 47 | Abnormal auditory evoked potentials (HP:0006958) | 2.34628721 |
| 48 | Optic disc pallor (HP:0000543) | 2.31752329 |
| 49 | Aplastic anemia (HP:0001915) | 2.31630216 |
| 50 | Hypoproteinemia (HP:0003075) | 2.31613692 |
| 51 | Congenital, generalized hypertrichosis (HP:0004540) | 2.28442919 |
| 52 | Metabolic acidosis (HP:0001942) | 2.24960051 |
| 53 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.22196792 |
| 54 | Abolished electroretinogram (ERG) (HP:0000550) | 2.17914535 |
| 55 | Hypoplastic nipples (HP:0002557) | 2.17437066 |
| 56 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.16464623 |
| 57 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.16464623 |
| 58 | Increased intramyocellular lipid droplets (HP:0012240) | 2.12830304 |
| 59 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.11928181 |
| 60 | Abnormality of urine glucose concentration (HP:0011016) | 2.07483744 |
| 61 | Glycosuria (HP:0003076) | 2.07483744 |
| 62 | Increased IgM level (HP:0003496) | 2.05763393 |
| 63 | Chorioretinal coloboma (HP:0000567) | 2.05630237 |
| 64 | Polyneuropathy (HP:0001271) | 2.04495997 |
| 65 | Epiphyseal stippling (HP:0010655) | 2.04268558 |
| 66 | Palpebral edema (HP:0100540) | 2.03990443 |
| 67 | Wide intermamillary distance (HP:0006610) | 1.98868114 |
| 68 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.98805062 |
| 69 | Congenital stationary night blindness (HP:0007642) | 1.97409159 |
| 70 | Abnormal number of erythroid precursors (HP:0012131) | 1.96646098 |
| 71 | Sudden death (HP:0001699) | 1.95923057 |
| 72 | Clubbing of toes (HP:0100760) | 1.94233847 |
| 73 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.93909660 |
| 74 | IgG deficiency (HP:0004315) | 1.92458264 |
| 75 | Conjunctival hamartoma (HP:0100780) | 1.92379005 |
| 76 | Generalized aminoaciduria (HP:0002909) | 1.91141129 |
| 77 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.90763533 |
| 78 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88869946 |
| 79 | Hypoplasia of the uterus (HP:0000013) | 1.82267471 |
| 80 | Pancreatic fibrosis (HP:0100732) | 1.79586759 |
| 81 | Leukodystrophy (HP:0002415) | 1.78378316 |
| 82 | Abnormality of renal resorption (HP:0011038) | 1.77587796 |
| 83 | Exertional dyspnea (HP:0002875) | 1.76559613 |
| 84 | Pancreatic cysts (HP:0001737) | 1.76332229 |
| 85 | Increased muscle lipid content (HP:0009058) | 1.76173551 |
| 86 | Female pseudohermaphroditism (HP:0010458) | 1.74644161 |
| 87 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.72945397 |
| 88 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.72714472 |
| 89 | Lethargy (HP:0001254) | 1.71044477 |
| 90 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.70068077 |
| 91 | Polymicrogyria (HP:0002126) | 1.69024966 |
| 92 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.68632497 |
| 93 | Decreased muscle mass (HP:0003199) | 1.64881038 |
| 94 | Type I transferrin isoform profile (HP:0003642) | 1.63089657 |
| 95 | Transposition of the great arteries (HP:0001669) | 1.61986221 |
| 96 | Abnormal connection of the cardiac segments (HP:0011545) | 1.61986221 |
| 97 | Abnormal ventriculo-arterial connection (HP:0011563) | 1.61986221 |
| 98 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.61985896 |
| 99 | Severe combined immunodeficiency (HP:0004430) | 1.61683248 |
| 100 | Increased number of teeth (HP:0011069) | 1.61342572 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MKNK2 | 9.75228463 |
| 2 | MKNK1 | 5.96558754 |
| 3 | TAOK2 | 4.45512129 |
| 4 | TAOK1 | 4.15286873 |
| 5 | MAP3K11 | 3.52074381 |
| 6 | MAP3K3 | 2.87221098 |
| 7 | VRK2 | 2.58538719 |
| 8 | MAP2K3 | 2.50598446 |
| 9 | JAK3 | 2.02102376 |
| 10 | KDR | 1.79903283 |
| 11 | ABL2 | 1.76127779 |
| 12 | BUB1 | 1.71468316 |
| 13 | SRPK1 | 1.70919184 |
| 14 | ZAK | 1.45772759 |
| 15 | TLK1 | 1.45661865 |
| 16 | TIE1 | 1.40307957 |
| 17 | VRK1 | 1.39806864 |
| 18 | TESK2 | 1.37158049 |
| 19 | MAP4K2 | 1.35328293 |
| 20 | DYRK1A | 1.33120055 |
| 21 | BCKDK | 1.22307727 |
| 22 | NUAK1 | 1.22208805 |
| 23 | TAF1 | 1.12357047 |
| 24 | CDK19 | 1.04222127 |
| 25 | MAP3K12 | 1.01910467 |
| 26 | WNK4 | 1.00990173 |
| 27 | TXK | 0.95373016 |
| 28 | CHEK2 | 0.93439404 |
| 29 | MAP3K5 | 0.89079289 |
| 30 | ADRBK2 | 0.89022971 |
| 31 | CSNK1G3 | 0.78368748 |
| 32 | NME2 | 0.75582186 |
| 33 | GRK1 | 0.73710874 |
| 34 | PRKCQ | 0.66586657 |
| 35 | CSNK1G1 | 0.63594046 |
| 36 | NEK1 | 0.61865364 |
| 37 | CSNK1G2 | 0.59273495 |
| 38 | GRK7 | 0.58794278 |
| 39 | CSNK1A1L | 0.57330523 |
| 40 | PHKG1 | 0.57223683 |
| 41 | PHKG2 | 0.57223683 |
| 42 | OXSR1 | 0.56678784 |
| 43 | TRIM28 | 0.54745601 |
| 44 | AURKA | 0.54577301 |
| 45 | DAPK1 | 0.53881527 |
| 46 | OBSCN | 0.53545141 |
| 47 | STK39 | 0.53018641 |
| 48 | MYLK | 0.51721195 |
| 49 | LIMK1 | 0.51498097 |
| 50 | STK16 | 0.47488048 |
| 51 | WNK3 | 0.47077593 |
| 52 | CSNK1A1 | 0.46609039 |
| 53 | RPS6KA5 | 0.46438810 |
| 54 | INSRR | 0.46128899 |
| 55 | FRK | 0.45443444 |
| 56 | BMPR1B | 0.43288645 |
| 57 | TESK1 | 0.42808860 |
| 58 | DAPK3 | 0.41203815 |
| 59 | MAP3K8 | 0.40873653 |
| 60 | DYRK2 | 0.39381946 |
| 61 | CDC7 | 0.36554355 |
| 62 | PDK2 | 0.35712027 |
| 63 | MAP3K1 | 0.35103937 |
| 64 | TEC | 0.33991581 |
| 65 | PLK3 | 0.31600758 |
| 66 | GRK5 | 0.30070650 |
| 67 | CSNK2A1 | 0.29389385 |
| 68 | CSNK2A2 | 0.28528539 |
| 69 | MAPKAPK3 | 0.28100194 |
| 70 | MUSK | 0.27007282 |
| 71 | PINK1 | 0.26359430 |
| 72 | EIF2AK3 | 0.25337953 |
| 73 | MAPKAPK5 | 0.24626908 |
| 74 | PIK3CG | 0.24511412 |
| 75 | BCR | 0.24508364 |
| 76 | PLK4 | 0.22837167 |
| 77 | PIK3CA | 0.22568279 |
| 78 | TNIK | 0.22006541 |
| 79 | NME1 | 0.21864961 |
| 80 | ITK | 0.21329491 |
| 81 | MAP4K1 | 0.20752920 |
| 82 | PRKCD | 0.19627901 |
| 83 | PLK2 | 0.19382038 |
| 84 | PRKCA | 0.19102126 |
| 85 | MAP2K7 | 0.17694655 |
| 86 | PRKACA | 0.17667317 |
| 87 | ADRBK1 | 0.16861552 |
| 88 | IGF1R | 0.16283100 |
| 89 | ATR | 0.16198338 |
| 90 | MST4 | 0.13732922 |
| 91 | PIM2 | 0.12549591 |
| 92 | TAOK3 | 0.12283329 |
| 93 | BLK | 0.12206585 |
| 94 | IKBKB | 0.11375103 |
| 95 | EPHB2 | 0.11289913 |
| 96 | KIT | 0.10736593 |
| 97 | CAMK2G | 0.09554735 |
| 98 | CSNK1E | 0.09429112 |
| 99 | ABL1 | 0.08727863 |
| 100 | PRKCG | 0.08491039 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.10963487 |
| 2 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 3.76087824 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.33846179 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.97673727 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.81169459 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.71004057 |
| 7 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.68884610 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.45628945 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.07600764 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.01499244 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 1.97495216 |
| 12 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.83318897 |
| 13 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.72767825 |
| 14 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.71229849 |
| 15 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.61907808 |
| 16 | Asthma_Homo sapiens_hsa05310 | 1.60384259 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.53699876 |
| 18 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.50340132 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.49697631 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.48786570 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.35525318 |
| 22 | Taste transduction_Homo sapiens_hsa04742 | 1.35244940 |
| 23 | Allograft rejection_Homo sapiens_hsa05330 | 1.34816652 |
| 24 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.34492789 |
| 25 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.29378379 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.27601232 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26977761 |
| 28 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.25950939 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.25881505 |
| 30 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.25580125 |
| 31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.24211772 |
| 32 | Peroxisome_Homo sapiens_hsa04146 | 1.22426640 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.11101120 |
| 34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.10818187 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.10707495 |
| 36 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.09364411 |
| 37 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.08278591 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.07713342 |
| 39 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.96750209 |
| 40 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.96392183 |
| 41 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.93015380 |
| 42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.92042069 |
| 43 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.88781157 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.86857207 |
| 45 | DNA replication_Homo sapiens_hsa03030 | 0.85947699 |
| 46 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.84634413 |
| 47 | RNA transport_Homo sapiens_hsa03013 | 0.83714979 |
| 48 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.82848476 |
| 49 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.81399648 |
| 50 | Alcoholism_Homo sapiens_hsa05034 | 0.81254326 |
| 51 | Mismatch repair_Homo sapiens_hsa03430 | 0.79868637 |
| 52 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79005552 |
| 53 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.78342520 |
| 54 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.78234880 |
| 55 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.77524788 |
| 56 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.75898488 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.74639980 |
| 58 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.74458474 |
| 59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.72847562 |
| 60 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.72404248 |
| 61 | Homologous recombination_Homo sapiens_hsa03440 | 0.71637265 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.71515524 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.70614090 |
| 64 | Viral myocarditis_Homo sapiens_hsa05416 | 0.69617446 |
| 65 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.66261142 |
| 66 | RNA degradation_Homo sapiens_hsa03018 | 0.65968445 |
| 67 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.64892077 |
| 68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.64888085 |
| 69 | Carbon metabolism_Homo sapiens_hsa01200 | 0.63698183 |
| 70 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.63265717 |
| 71 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.62633556 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61569344 |
| 73 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.60371015 |
| 74 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59661713 |
| 75 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.57882298 |
| 76 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.57832160 |
| 77 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.55935628 |
| 78 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.55253555 |
| 79 | Spliceosome_Homo sapiens_hsa03040 | 0.55161101 |
| 80 | Sulfur relay system_Homo sapiens_hsa04122 | 0.55089338 |
| 81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.54314646 |
| 82 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52443068 |
| 83 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.51925709 |
| 84 | Phototransduction_Homo sapiens_hsa04744 | 0.51835539 |
| 85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.49829453 |
| 86 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.48996130 |
| 87 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.48700580 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47957520 |
| 89 | Base excision repair_Homo sapiens_hsa03410 | 0.46681719 |
| 90 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.44354679 |
| 91 | Basal transcription factors_Homo sapiens_hsa03022 | 0.43581874 |
| 92 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.42457344 |
| 93 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.41957573 |
| 94 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.39664853 |
| 95 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.38664465 |
| 96 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.37974208 |
| 97 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.37882841 |
| 98 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.37260331 |
| 99 | Nicotine addiction_Homo sapiens_hsa05033 | 0.37178348 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37114927 |

