

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.99886949 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.53550900 |
| 3 | thalamus development (GO:0021794) | 5.08190457 |
| 4 | cytidine metabolic process (GO:0046087) | 4.86939371 |
| 5 | cytidine catabolic process (GO:0006216) | 4.86939371 |
| 6 | cytidine deamination (GO:0009972) | 4.86939371 |
| 7 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.66930889 |
| 8 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.66930889 |
| 9 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.66051912 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.66051912 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 4.66051912 |
| 12 | protein neddylation (GO:0045116) | 4.60255600 |
| 13 | protein complex biogenesis (GO:0070271) | 4.55557645 |
| 14 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.54535822 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 4.46920567 |
| 16 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.46920567 |
| 17 | response to gravity (GO:0009629) | 4.42965355 |
| 18 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.36955967 |
| 19 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.36383468 |
| 20 | negative regulation of thymocyte apoptotic process (GO:0070244) | 4.22445495 |
| 21 | cullin deneddylation (GO:0010388) | 3.98164122 |
| 22 | chaperone-mediated protein transport (GO:0072321) | 3.86817953 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.81501348 |
| 24 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.74892643 |
| 25 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.71220590 |
| 26 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.67484505 |
| 27 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.66161467 |
| 28 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.60358589 |
| 29 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.60358589 |
| 30 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.60358589 |
| 31 | polyamine biosynthetic process (GO:0006596) | 3.58414730 |
| 32 | protein deneddylation (GO:0000338) | 3.56978557 |
| 33 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.56417058 |
| 34 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.56417058 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.53993066 |
| 36 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.49543059 |
| 37 | respiratory electron transport chain (GO:0022904) | 3.49508255 |
| 38 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.45081043 |
| 39 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.45081043 |
| 40 | electron transport chain (GO:0022900) | 3.44319328 |
| 41 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.43692342 |
| 42 | signal peptide processing (GO:0006465) | 3.42198686 |
| 43 | pseudouridine synthesis (GO:0001522) | 3.38944084 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.37882665 |
| 45 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.34102076 |
| 46 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.33972031 |
| 47 | skeletal muscle tissue regeneration (GO:0043403) | 3.32025020 |
| 48 | regulation of thymocyte apoptotic process (GO:0070243) | 3.31962047 |
| 49 | proteasome assembly (GO:0043248) | 3.25783856 |
| 50 | termination of RNA polymerase I transcription (GO:0006363) | 3.23201550 |
| 51 | maturation of 5.8S rRNA (GO:0000460) | 3.23152170 |
| 52 | transcription from RNA polymerase I promoter (GO:0006360) | 3.18218825 |
| 53 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.17200192 |
| 54 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.15205388 |
| 55 | nucleobase biosynthetic process (GO:0046112) | 3.09848354 |
| 56 | purine nucleobase biosynthetic process (GO:0009113) | 3.07669248 |
| 57 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.07456030 |
| 58 | skeletal muscle adaptation (GO:0043501) | 3.07118146 |
| 59 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.01500460 |
| 60 | negative regulation of ligase activity (GO:0051352) | 3.01077820 |
| 61 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.01077820 |
| 62 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.95381895 |
| 63 | positive regulation of cell cycle arrest (GO:0071158) | 2.95070620 |
| 64 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.93261648 |
| 65 | termination of RNA polymerase III transcription (GO:0006386) | 2.93261648 |
| 66 | intracellular protein transmembrane import (GO:0044743) | 2.91347158 |
| 67 | postreplication repair (GO:0006301) | 2.88313211 |
| 68 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.87983279 |
| 69 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.87430989 |
| 70 | rRNA processing (GO:0006364) | 2.87164768 |
| 71 | protein K6-linked ubiquitination (GO:0085020) | 2.87161566 |
| 72 | DNA damage response, detection of DNA damage (GO:0042769) | 2.84680653 |
| 73 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.84366334 |
| 74 | regulation of centriole replication (GO:0046599) | 2.83683504 |
| 75 | response to muscle activity (GO:0014850) | 2.83367654 |
| 76 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.80897857 |
| 77 | IMP biosynthetic process (GO:0006188) | 2.80355851 |
| 78 | striated muscle atrophy (GO:0014891) | 2.79339933 |
| 79 | negative regulation of muscle hypertrophy (GO:0014741) | 2.76565533 |
| 80 | peptidyl-histidine modification (GO:0018202) | 2.75900332 |
| 81 | regulation of chronic inflammatory response (GO:0002676) | 2.75350354 |
| 82 | cellular biogenic amine biosynthetic process (GO:0042401) | 2.74750744 |
| 83 | rRNA metabolic process (GO:0016072) | 2.73492783 |
| 84 | maturation of SSU-rRNA (GO:0030490) | 2.71864010 |
| 85 | regulation of timing of cell differentiation (GO:0048505) | 2.69461132 |
| 86 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 2.67892996 |
| 87 | respiratory chain complex IV assembly (GO:0008535) | 2.67409888 |
| 88 | protein targeting to mitochondrion (GO:0006626) | 2.67223924 |
| 89 | inner mitochondrial membrane organization (GO:0007007) | 2.63865196 |
| 90 | rRNA modification (GO:0000154) | 2.63464943 |
| 91 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.62105109 |
| 92 | cytochrome complex assembly (GO:0017004) | 2.61188785 |
| 93 | actin-myosin filament sliding (GO:0033275) | 2.59720883 |
| 94 | muscle filament sliding (GO:0030049) | 2.59720883 |
| 95 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.58990437 |
| 96 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.57837465 |
| 97 | ATP biosynthetic process (GO:0006754) | 2.57721998 |
| 98 | muscle atrophy (GO:0014889) | 2.55810222 |
| 99 | negative regulation of heart rate (GO:0010459) | 2.54199753 |
| 100 | protein localization to mitochondrion (GO:0070585) | 2.54101013 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.10372311 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.52230145 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.47486163 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 4.10787021 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.64129153 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.48327870 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.96181095 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.79709155 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.73681005 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.73244980 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.69042850 |
| 12 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.52608215 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.37437594 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.36868753 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.31795900 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.24325459 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.09725766 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.07596618 |
| 19 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.07342521 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.04171168 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.03573788 |
| 22 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.96199697 |
| 23 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.88373005 |
| 24 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.80512457 |
| 25 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.80030950 |
| 26 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.77882202 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.73475998 |
| 28 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.69805720 |
| 29 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.67978167 |
| 30 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.67146094 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.66583778 |
| 32 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.65369374 |
| 33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.59670937 |
| 34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.58470927 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.57098157 |
| 36 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.54525182 |
| 37 | FUS_26573619_Chip-Seq_HEK293_Human | 1.52240482 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.51697099 |
| 39 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.50687658 |
| 40 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.48941192 |
| 41 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.48930486 |
| 42 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.48265679 |
| 43 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.41602937 |
| 44 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41084687 |
| 45 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.39118815 |
| 46 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.38760672 |
| 47 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.37252026 |
| 48 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.36842750 |
| 49 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.35191293 |
| 50 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33783930 |
| 51 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.33284098 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.32287793 |
| 53 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.31200063 |
| 54 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.29971902 |
| 55 | P300_19829295_ChIP-Seq_ESCs_Human | 1.25992602 |
| 56 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.22947164 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.22077943 |
| 58 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.20730911 |
| 59 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.19491259 |
| 60 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.17265674 |
| 61 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.15024011 |
| 62 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.14790584 |
| 63 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.14748600 |
| 64 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.13375277 |
| 65 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12693556 |
| 66 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12693556 |
| 67 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.07672681 |
| 68 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.06968820 |
| 69 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.06555385 |
| 70 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06250168 |
| 71 | GATA1_22025678_ChIP-Seq_K562_Human | 1.05511222 |
| 72 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05338132 |
| 73 | AR_20517297_ChIP-Seq_VCAP_Human | 1.05298202 |
| 74 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.05160243 |
| 75 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.03201416 |
| 76 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.02861379 |
| 77 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.02350832 |
| 78 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.99795576 |
| 79 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.97261979 |
| 80 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95942654 |
| 81 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.94824210 |
| 82 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.93691814 |
| 83 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92033765 |
| 84 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.91564408 |
| 85 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.91323538 |
| 86 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.89804854 |
| 87 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.87968914 |
| 88 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.87255227 |
| 89 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.86979707 |
| 90 | NCOR_22424771_ChIP-Seq_293T_Human | 0.86189313 |
| 91 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.84881594 |
| 92 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.83522019 |
| 93 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.83522019 |
| 94 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81807560 |
| 95 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.81742726 |
| 96 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.80042426 |
| 97 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.80024258 |
| 98 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.80006012 |
| 99 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.79539856 |
| 100 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.79535641 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005083_abnormal_biliary_tract | 4.01441813 |
| 2 | MP0005085_abnormal_gallbladder_physiolo | 3.62582460 |
| 3 | MP0004145_abnormal_muscle_electrophysio | 3.20964645 |
| 4 | MP0000566_synostosis | 2.89208778 |
| 5 | MP0002822_catalepsy | 2.85204422 |
| 6 | MP0001529_abnormal_vocalization | 2.63467134 |
| 7 | MP0000569_abnormal_digit_pigmentation | 2.54439226 |
| 8 | MP0002102_abnormal_ear_morphology | 2.50794610 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.44092623 |
| 10 | MP0003718_maternal_effect | 2.43888581 |
| 11 | MP0004142_abnormal_muscle_tone | 2.36764514 |
| 12 | MP0008872_abnormal_physiological_respon | 2.35848992 |
| 13 | MP0002138_abnormal_hepatobiliary_system | 2.26205930 |
| 14 | MP0002163_abnormal_gland_morphology | 2.25515527 |
| 15 | MP0003252_abnormal_bile_duct | 2.23013890 |
| 16 | MP0000749_muscle_degeneration | 2.19491092 |
| 17 | MP0000372_irregular_coat_pigmentation | 2.02987887 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 2.00423331 |
| 19 | MP0002736_abnormal_nociception_after | 1.91786428 |
| 20 | MP0001835_abnormal_antigen_presentation | 1.87223125 |
| 21 | MP0008004_abnormal_stomach_pH | 1.85219669 |
| 22 | MP0003186_abnormal_redox_activity | 1.84043652 |
| 23 | MP0004084_abnormal_cardiac_muscle | 1.81029302 |
| 24 | MP0003806_abnormal_nucleotide_metabolis | 1.79953165 |
| 25 | MP0004147_increased_porphyrin_level | 1.78331984 |
| 26 | MP0005645_abnormal_hypothalamus_physiol | 1.63799644 |
| 27 | MP0000490_abnormal_crypts_of | 1.62533210 |
| 28 | MP0002089_abnormal_postnatal_growth/wei | 1.59773961 |
| 29 | MP0003786_premature_aging | 1.55594280 |
| 30 | MP0004036_abnormal_muscle_relaxation | 1.54969662 |
| 31 | MP0000747_muscle_weakness | 1.53190333 |
| 32 | MP0009785_altered_susceptibility_to | 1.52802755 |
| 33 | MP0001873_stomach_inflammation | 1.47628501 |
| 34 | MP0003959_abnormal_lean_body | 1.47234034 |
| 35 | MP0002837_dystrophic_cardiac_calcinosis | 1.46247194 |
| 36 | MP0005671_abnormal_response_to | 1.44345030 |
| 37 | MP0005379_endocrine/exocrine_gland_phen | 1.43108135 |
| 38 | MP0004957_abnormal_blastocyst_morpholog | 1.41809369 |
| 39 | MP0005365_abnormal_bile_salt | 1.41081792 |
| 40 | MP0001968_abnormal_touch/_nociception | 1.36501759 |
| 41 | MP0002166_altered_tumor_susceptibility | 1.35843974 |
| 42 | MP0001348_abnormal_lacrimal_gland | 1.34206087 |
| 43 | MP0009697_abnormal_copulation | 1.28184170 |
| 44 | MP0005464_abnormal_platelet_physiology | 1.24369163 |
| 45 | MP0000685_abnormal_immune_system | 1.23266733 |
| 46 | MP0008569_lethality_at_weaning | 1.22386982 |
| 47 | MP0005670_abnormal_white_adipose | 1.21953956 |
| 48 | MP0005387_immune_system_phenotype | 1.18997238 |
| 49 | MP0001790_abnormal_immune_system | 1.18997238 |
| 50 | MP0002006_tumorigenesis | 1.17931680 |
| 51 | MP0003045_fibrosis | 1.17416948 |
| 52 | MP0003950_abnormal_plasma_membrane | 1.15887022 |
| 53 | MP0003693_abnormal_embryo_hatching | 1.10723445 |
| 54 | MP0005167_abnormal_blood-brain_barrier | 1.09689476 |
| 55 | MP0009745_abnormal_behavioral_response | 1.08904702 |
| 56 | MP0008057_abnormal_DNA_replication | 1.05601467 |
| 57 | MP0008877_abnormal_DNA_methylation | 1.05443861 |
| 58 | MP0002277_abnormal_respiratory_mucosa | 1.05294523 |
| 59 | MP0002733_abnormal_thermal_nociception | 1.00415211 |
| 60 | MP0005551_abnormal_eye_electrophysiolog | 1.00182297 |
| 61 | MP0002148_abnormal_hypersensitivity_rea | 1.00013968 |
| 62 | MP0006072_abnormal_retinal_apoptosis | 0.96118787 |
| 63 | MP0001800_abnormal_humoral_immune | 0.94505818 |
| 64 | MP0009333_abnormal_splenocyte_physiolog | 0.93739433 |
| 65 | MP0000427_abnormal_hair_cycle | 0.92970362 |
| 66 | MP0005620_abnormal_muscle_contractility | 0.91903073 |
| 67 | MP0006035_abnormal_mitochondrial_morpho | 0.91791767 |
| 68 | MP0000015_abnormal_ear_pigmentation | 0.89471582 |
| 69 | MP0001905_abnormal_dopamine_level | 0.86099048 |
| 70 | MP0009765_abnormal_xenobiotic_induced | 0.85449439 |
| 71 | MP0001666_abnormal_nutrient_absorption | 0.85007976 |
| 72 | MP0004215_abnormal_myocardial_fiber | 0.83953736 |
| 73 | MP0005075_abnormal_melanosome_morpholog | 0.82962518 |
| 74 | MP0003866_abnormal_defecation | 0.82707743 |
| 75 | MP0002234_abnormal_pharynx_morphology | 0.82046466 |
| 76 | MP0001664_abnormal_digestion | 0.81817862 |
| 77 | MP0002269_muscular_atrophy | 0.81622834 |
| 78 | MP0002095_abnormal_skin_pigmentation | 0.80975639 |
| 79 | MP0005636_abnormal_mineral_homeostasis | 0.79313781 |
| 80 | MP0005310_abnormal_salivary_gland | 0.76817489 |
| 81 | MP0009053_abnormal_anal_canal | 0.76608384 |
| 82 | MP0000477_abnormal_intestine_morphology | 0.74074421 |
| 83 | MP0008995_early_reproductive_senescence | 0.73276018 |
| 84 | MP0006036_abnormal_mitochondrial_physio | 0.73147876 |
| 85 | MP0001663_abnormal_digestive_system | 0.72706054 |
| 86 | MP0004381_abnormal_hair_follicle | 0.72001962 |
| 87 | MP0005646_abnormal_pituitary_gland | 0.71497569 |
| 88 | MP0001970_abnormal_pain_threshold | 0.71062018 |
| 89 | MP0010155_abnormal_intestine_physiology | 0.69394706 |
| 90 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.69282574 |
| 91 | MP0005174_abnormal_tail_pigmentation | 0.69232054 |
| 92 | MP0001293_anophthalmia | 0.68988853 |
| 93 | MP0003077_abnormal_cell_cycle | 0.68098950 |
| 94 | MP0002272_abnormal_nervous_system | 0.67833668 |
| 95 | MP0003878_abnormal_ear_physiology | 0.66717970 |
| 96 | MP0005377_hearing/vestibular/ear_phenot | 0.66717970 |
| 97 | MP0002210_abnormal_sex_determination | 0.65937536 |
| 98 | MP0005395_other_phenotype | 0.64104367 |
| 99 | MP0009764_decreased_sensitivity_to | 0.63357662 |
| 100 | MP0010030_abnormal_orbit_morphology | 0.62188176 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.68087424 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.91662712 |
| 3 | Acute encephalopathy (HP:0006846) | 4.91428051 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.73698618 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.70558121 |
| 6 | Palpebral edema (HP:0100540) | 4.48910989 |
| 7 | Increased CSF lactate (HP:0002490) | 4.25501419 |
| 8 | Hepatocellular necrosis (HP:0001404) | 4.14785827 |
| 9 | Hepatic necrosis (HP:0002605) | 4.05813857 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.75145265 |
| 11 | Cerebral edema (HP:0002181) | 3.22013067 |
| 12 | Congenital stationary night blindness (HP:0007642) | 3.14667387 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.14341707 |
| 14 | Congenital, generalized hypertrichosis (HP:0004540) | 3.09154329 |
| 15 | Generalized aminoaciduria (HP:0002909) | 3.05773274 |
| 16 | Hypoproteinemia (HP:0003075) | 2.94998446 |
| 17 | Increased serum lactate (HP:0002151) | 2.88538683 |
| 18 | Optic disc pallor (HP:0000543) | 2.84832223 |
| 19 | Exertional dyspnea (HP:0002875) | 2.84443695 |
| 20 | Stomatitis (HP:0010280) | 2.83418729 |
| 21 | Leukodystrophy (HP:0002415) | 2.73647064 |
| 22 | Respiratory failure (HP:0002878) | 2.72112149 |
| 23 | Renal Fanconi syndrome (HP:0001994) | 2.71957094 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 2.71818619 |
| 25 | Type II lissencephaly (HP:0007260) | 2.69244922 |
| 26 | Stenosis of the external auditory canal (HP:0000402) | 2.65891261 |
| 27 | Inability to walk (HP:0002540) | 2.63321338 |
| 28 | Exercise intolerance (HP:0003546) | 2.58554486 |
| 29 | Oligodactyly (hands) (HP:0001180) | 2.58393378 |
| 30 | Conjugated hyperbilirubinemia (HP:0002908) | 2.50571338 |
| 31 | IgG deficiency (HP:0004315) | 2.50268041 |
| 32 | Lactic acidosis (HP:0003128) | 2.44134410 |
| 33 | Abnormal pupillary function (HP:0007686) | 2.43003849 |
| 34 | Paralysis (HP:0003470) | 2.42174399 |
| 35 | Colon cancer (HP:0003003) | 2.38051824 |
| 36 | Neoplasm of the adrenal cortex (HP:0100641) | 2.36399866 |
| 37 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.32667897 |
| 38 | Abnormality of the renal cortex (HP:0011035) | 2.30785649 |
| 39 | Respiratory difficulties (HP:0002880) | 2.30307731 |
| 40 | Abnormality of the labia minora (HP:0012880) | 2.29863381 |
| 41 | Fair hair (HP:0002286) | 2.26353977 |
| 42 | Hypothermia (HP:0002045) | 2.25647017 |
| 43 | Periorbital edema (HP:0100539) | 2.24265497 |
| 44 | Methylmalonic aciduria (HP:0012120) | 2.24262293 |
| 45 | Absent phalangeal crease (HP:0006109) | 2.21907203 |
| 46 | Increased intramyocellular lipid droplets (HP:0012240) | 2.20535961 |
| 47 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.19666752 |
| 48 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.19666752 |
| 49 | Facial edema (HP:0000282) | 2.19479996 |
| 50 | Pendular nystagmus (HP:0012043) | 2.16834169 |
| 51 | Testicular atrophy (HP:0000029) | 2.14905576 |
| 52 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.12192081 |
| 53 | Palpitations (HP:0001962) | 2.11371214 |
| 54 | Myoglobinuria (HP:0002913) | 2.10431678 |
| 55 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.06810137 |
| 56 | Abnormal albumin level (HP:0012116) | 2.04932515 |
| 57 | Hypoalbuminemia (HP:0003073) | 2.04932515 |
| 58 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.04582931 |
| 59 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.04018416 |
| 60 | Gaze-evoked nystagmus (HP:0000640) | 2.01854204 |
| 61 | Abnormal hair whorl (HP:0010721) | 2.01498902 |
| 62 | Optic nerve hypoplasia (HP:0000609) | 1.98512217 |
| 63 | Abnormality of the pons (HP:0007361) | 1.97770090 |
| 64 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.96582036 |
| 65 | Petechiae (HP:0000967) | 1.95784202 |
| 66 | 2-3 toe syndactyly (HP:0004691) | 1.92713350 |
| 67 | Abnormality of purine metabolism (HP:0004352) | 1.91897515 |
| 68 | X-linked dominant inheritance (HP:0001423) | 1.91621590 |
| 69 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.91400033 |
| 70 | Anterior segment dysgenesis (HP:0007700) | 1.91309403 |
| 71 | Molar tooth sign on MRI (HP:0002419) | 1.90646305 |
| 72 | Abnormality of midbrain morphology (HP:0002418) | 1.90646305 |
| 73 | Abnormal finger flexion creases (HP:0006143) | 1.90063270 |
| 74 | Muscle fiber atrophy (HP:0100295) | 1.89642214 |
| 75 | Hypoplasia of the pons (HP:0012110) | 1.88482681 |
| 76 | Abnormality of macular pigmentation (HP:0008002) | 1.88243423 |
| 77 | Volvulus (HP:0002580) | 1.87288230 |
| 78 | Renal cortical cysts (HP:0000803) | 1.87187813 |
| 79 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.83460238 |
| 80 | Round ear (HP:0100830) | 1.83218725 |
| 81 | Pancreatic cysts (HP:0001737) | 1.81658826 |
| 82 | Split foot (HP:0001839) | 1.81105067 |
| 83 | Type 2 muscle fiber atrophy (HP:0003554) | 1.81074381 |
| 84 | Hypophosphatemic rickets (HP:0004912) | 1.79530041 |
| 85 | Lethargy (HP:0001254) | 1.79435906 |
| 86 | Hypoplasia of the uterus (HP:0000013) | 1.75859801 |
| 87 | Increased serum pyruvate (HP:0003542) | 1.73091547 |
| 88 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.72037869 |
| 89 | Abnormality of alanine metabolism (HP:0010916) | 1.72037869 |
| 90 | Hyperalaninemia (HP:0003348) | 1.72037869 |
| 91 | Nephronophthisis (HP:0000090) | 1.71853719 |
| 92 | Neoplasm of the adrenal gland (HP:0100631) | 1.71526789 |
| 93 | Oligodactyly (HP:0012165) | 1.70647243 |
| 94 | Nemaline bodies (HP:0003798) | 1.70104235 |
| 95 | Upper limb muscle weakness (HP:0003484) | 1.69364074 |
| 96 | Limb hypertonia (HP:0002509) | 1.67413163 |
| 97 | Keratoconus (HP:0000563) | 1.67172673 |
| 98 | Increased corneal curvature (HP:0100692) | 1.67172673 |
| 99 | Death in childhood (HP:0003819) | 1.66888496 |
| 100 | Cheilitis (HP:0100825) | 1.64984474 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 5.30155648 |
| 2 | EIF2AK1 | 4.12641129 |
| 3 | TSSK6 | 3.35119263 |
| 4 | MST4 | 3.24132821 |
| 5 | TAF1 | 2.98439279 |
| 6 | NUAK1 | 2.67776496 |
| 7 | TXK | 2.50809853 |
| 8 | LMTK2 | 2.44385176 |
| 9 | EIF2AK3 | 2.43586755 |
| 10 | WNK4 | 2.39593539 |
| 11 | PHKG2 | 2.26133787 |
| 12 | PHKG1 | 2.26133787 |
| 13 | TAOK3 | 2.23310826 |
| 14 | BUB1 | 2.03454257 |
| 15 | TEC | 2.02887344 |
| 16 | NEK1 | 1.90394784 |
| 17 | PINK1 | 1.90370384 |
| 18 | VRK1 | 1.79801454 |
| 19 | PIM2 | 1.76124515 |
| 20 | ZAK | 1.69128690 |
| 21 | ARAF | 1.60817769 |
| 22 | NME1 | 1.54180290 |
| 23 | ADRBK2 | 1.46253985 |
| 24 | STK39 | 1.36709447 |
| 25 | GRK5 | 1.36320098 |
| 26 | OXSR1 | 1.35356948 |
| 27 | WNK1 | 1.35339709 |
| 28 | GRK1 | 1.34091997 |
| 29 | PLK3 | 1.29818813 |
| 30 | TIE1 | 1.21927457 |
| 31 | CSNK1G1 | 1.18084744 |
| 32 | SMG1 | 1.15458341 |
| 33 | SRPK1 | 1.15430077 |
| 34 | CSNK1G3 | 1.15163988 |
| 35 | EIF2AK2 | 1.14105180 |
| 36 | MAPKAPK3 | 1.11521562 |
| 37 | CSNK1A1L | 1.10066526 |
| 38 | PIK3CG | 1.09096322 |
| 39 | OBSCN | 1.08022225 |
| 40 | CSNK1G2 | 1.04790014 |
| 41 | PBK | 0.99562633 |
| 42 | DAPK1 | 0.96743922 |
| 43 | DYRK2 | 0.96171448 |
| 44 | MAP3K12 | 0.95713453 |
| 45 | TNK2 | 0.94067648 |
| 46 | CDC7 | 0.91167700 |
| 47 | MAP2K6 | 0.89443628 |
| 48 | TYRO3 | 0.87302000 |
| 49 | ITK | 0.86379314 |
| 50 | CAMK2G | 0.84401668 |
| 51 | TLK1 | 0.79282467 |
| 52 | MKNK2 | 0.78850660 |
| 53 | PASK | 0.76318417 |
| 54 | BCKDK | 0.74159640 |
| 55 | BCR | 0.71925337 |
| 56 | STK4 | 0.71468847 |
| 57 | BRAF | 0.70068079 |
| 58 | TRIM28 | 0.69766144 |
| 59 | PLK2 | 0.64225978 |
| 60 | DAPK3 | 0.62033484 |
| 61 | IKBKE | 0.60430119 |
| 62 | WNK3 | 0.58447663 |
| 63 | PRKCE | 0.58335641 |
| 64 | TGFBR1 | 0.55675889 |
| 65 | AKT3 | 0.54121174 |
| 66 | BMPR1B | 0.54075124 |
| 67 | PIM1 | 0.52630754 |
| 68 | FRK | 0.52549320 |
| 69 | MAPKAPK5 | 0.51632230 |
| 70 | PRKG2 | 0.49612980 |
| 71 | ATR | 0.49555417 |
| 72 | MELK | 0.48316134 |
| 73 | CHEK2 | 0.47583512 |
| 74 | PLK4 | 0.46927522 |
| 75 | ADRBK1 | 0.46047315 |
| 76 | MKNK1 | 0.45598787 |
| 77 | PRKCG | 0.43815546 |
| 78 | PDK2 | 0.43656475 |
| 79 | CAMKK2 | 0.43273719 |
| 80 | STK16 | 0.41768046 |
| 81 | IKBKB | 0.41565757 |
| 82 | PTK2B | 0.37355950 |
| 83 | PAK4 | 0.35688890 |
| 84 | RPS6KA5 | 0.34451479 |
| 85 | CSNK1A1 | 0.32163107 |
| 86 | WEE1 | 0.31455995 |
| 87 | SIK3 | 0.31252858 |
| 88 | TYK2 | 0.31208768 |
| 89 | GRK7 | 0.30821609 |
| 90 | KDR | 0.30580569 |
| 91 | PRKCI | 0.30487683 |
| 92 | MYLK | 0.30192176 |
| 93 | CSNK2A1 | 0.26159403 |
| 94 | NME2 | 0.25650123 |
| 95 | PAK1 | 0.25308191 |
| 96 | PRKG1 | 0.24674758 |
| 97 | CAMK2A | 0.24220720 |
| 98 | MAPK13 | 0.23796901 |
| 99 | CSNK1E | 0.23537129 |
| 100 | PRKCQ | 0.23369161 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.33796308 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.67248295 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.38583447 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.93871319 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.90730376 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.88371175 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.54187766 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.36157225 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.17965176 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.16434045 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.10933667 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 2.01362517 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.90268120 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.87994527 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.83431599 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.68715835 |
| 17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.66582655 |
| 18 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.63886104 |
| 19 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.53815510 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.49707376 |
| 21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.42827126 |
| 22 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.39816261 |
| 23 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.39434983 |
| 24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.36383481 |
| 25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34781998 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.33397678 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.30311167 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.28859772 |
| 29 | Purine metabolism_Homo sapiens_hsa00230 | 1.27470199 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.27099079 |
| 31 | RNA transport_Homo sapiens_hsa03013 | 1.26933900 |
| 32 | Mismatch repair_Homo sapiens_hsa03430 | 1.24658730 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.20151980 |
| 34 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.17162688 |
| 35 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15800541 |
| 36 | Spliceosome_Homo sapiens_hsa03040 | 1.15640828 |
| 37 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.15522331 |
| 38 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.13139889 |
| 39 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.08826018 |
| 40 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.06365138 |
| 41 | Phototransduction_Homo sapiens_hsa04744 | 1.04400338 |
| 42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.01690721 |
| 43 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.98871561 |
| 44 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.98765020 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.93199624 |
| 46 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.89412263 |
| 47 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.85840218 |
| 48 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83100814 |
| 49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.82053707 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.78645759 |
| 51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.78384738 |
| 52 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.76445645 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75382187 |
| 54 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73856571 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.72007681 |
| 56 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.68878445 |
| 57 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.68378569 |
| 58 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.64975905 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63567442 |
| 60 | Nicotine addiction_Homo sapiens_hsa05033 | 0.63066808 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62086285 |
| 62 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.61998056 |
| 63 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.60600209 |
| 64 | Peroxisome_Homo sapiens_hsa04146 | 0.59348110 |
| 65 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.59295538 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58272219 |
| 67 | Circadian rhythm_Homo sapiens_hsa04710 | 0.55942477 |
| 68 | Tight junction_Homo sapiens_hsa04530 | 0.51652959 |
| 69 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.51551226 |
| 70 | Salivary secretion_Homo sapiens_hsa04970 | 0.50949157 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49288557 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.49206366 |
| 73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.49042906 |
| 74 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.44764793 |
| 75 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.43272752 |
| 76 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.40673537 |
| 77 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.40161730 |
| 78 | Measles_Homo sapiens_hsa05162 | 0.37308048 |
| 79 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36432175 |
| 80 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.36186552 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.36166823 |
| 82 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.36090773 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.35821453 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.35014437 |
| 85 | Morphine addiction_Homo sapiens_hsa05032 | 0.33772423 |
| 86 | Long-term depression_Homo sapiens_hsa04730 | 0.33494569 |
| 87 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.33325957 |
| 88 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.32594148 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.32406801 |
| 90 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.29748651 |
| 91 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.29733595 |
| 92 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.28439019 |
| 93 | ABC transporters_Homo sapiens_hsa02010 | 0.28107078 |
| 94 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.27579135 |
| 95 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.27018644 |
| 96 | Base excision repair_Homo sapiens_hsa03410 | 0.25204266 |
| 97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24056671 |
| 98 | Mineral absorption_Homo sapiens_hsa04978 | 0.22839300 |
| 99 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.22356420 |
| 100 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.22063235 |

