

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.06536426 |
| 2 | proteasome assembly (GO:0043248) | 5.70578291 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.63114777 |
| 4 | cullin deneddylation (GO:0010388) | 4.61935939 |
| 5 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.59894950 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.55073262 |
| 7 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.54274483 |
| 8 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.44527944 |
| 9 | protein deneddylation (GO:0000338) | 4.42881356 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 4.41977143 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.41977143 |
| 12 | maturation of 5.8S rRNA (GO:0000460) | 4.41191442 |
| 13 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.41099597 |
| 14 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.30594999 |
| 15 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.30594999 |
| 16 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.30594999 |
| 17 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.29121419 |
| 18 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.29121419 |
| 19 | chaperone-mediated protein transport (GO:0072321) | 4.26562635 |
| 20 | GTP biosynthetic process (GO:0006183) | 4.11740772 |
| 21 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.08760537 |
| 22 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.08255547 |
| 23 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.08255547 |
| 24 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.02352216 |
| 25 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.02352216 |
| 26 | NADH dehydrogenase complex assembly (GO:0010257) | 4.02352216 |
| 27 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 4.01580104 |
| 28 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.99350288 |
| 29 | negative regulation of ligase activity (GO:0051352) | 3.99350288 |
| 30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.96798455 |
| 31 | rRNA modification (GO:0000154) | 3.96013986 |
| 32 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.89518296 |
| 33 | cytidine metabolic process (GO:0046087) | 3.85965551 |
| 34 | cytidine catabolic process (GO:0006216) | 3.85965551 |
| 35 | cytidine deamination (GO:0009972) | 3.85965551 |
| 36 | protein complex biogenesis (GO:0070271) | 3.85692451 |
| 37 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.72148442 |
| 38 | regulation of response to tumor cell (GO:0002834) | 3.67301374 |
| 39 | positive regulation of response to tumor cell (GO:0002836) | 3.67301374 |
| 40 | positive regulation of immune response to tumor cell (GO:0002839) | 3.67301374 |
| 41 | regulation of immune response to tumor cell (GO:0002837) | 3.67301374 |
| 42 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.66563971 |
| 43 | UTP biosynthetic process (GO:0006228) | 3.59612693 |
| 44 | protein neddylation (GO:0045116) | 3.58538727 |
| 45 | termination of RNA polymerase III transcription (GO:0006386) | 3.55738193 |
| 46 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.55738193 |
| 47 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.49336052 |
| 48 | rRNA methylation (GO:0031167) | 3.45956390 |
| 49 | respiratory chain complex IV assembly (GO:0008535) | 3.45317254 |
| 50 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.41453286 |
| 51 | UTP metabolic process (GO:0046051) | 3.41448645 |
| 52 | positive regulation of cell cycle arrest (GO:0071158) | 3.38554700 |
| 53 | ribosome assembly (GO:0042255) | 3.38395865 |
| 54 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.38239113 |
| 55 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.34885186 |
| 56 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.34885186 |
| 57 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.30990804 |
| 58 | pseudouridine synthesis (GO:0001522) | 3.30902131 |
| 59 | peptidyl-histidine modification (GO:0018202) | 3.30483482 |
| 60 | regulation of cellular amine metabolic process (GO:0033238) | 3.29847086 |
| 61 | positive regulation of ligase activity (GO:0051351) | 3.28742463 |
| 62 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.25824712 |
| 63 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.25206353 |
| 64 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.20282117 |
| 65 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.19218053 |
| 66 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.14712085 |
| 67 | protein K6-linked ubiquitination (GO:0085020) | 3.14328711 |
| 68 | DNA double-strand break processing (GO:0000729) | 3.09295154 |
| 69 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.05127314 |
| 70 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.02356221 |
| 71 | CTP biosynthetic process (GO:0006241) | 3.01013676 |
| 72 | CTP metabolic process (GO:0046036) | 3.01013676 |
| 73 | respiratory electron transport chain (GO:0022904) | 3.00467317 |
| 74 | electron transport chain (GO:0022900) | 2.99430129 |
| 75 | negative regulation of mast cell activation (GO:0033004) | 2.98554916 |
| 76 | protein targeting to mitochondrion (GO:0006626) | 2.95548796 |
| 77 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.95127238 |
| 78 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.92970406 |
| 79 | platelet dense granule organization (GO:0060155) | 2.92632567 |
| 80 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.92106093 |
| 81 | termination of RNA polymerase I transcription (GO:0006363) | 2.90467831 |
| 82 | regulation of chronic inflammatory response (GO:0002676) | 2.87895661 |
| 83 | tRNA processing (GO:0008033) | 2.85828320 |
| 84 | regulation of ligase activity (GO:0051340) | 2.84425822 |
| 85 | negative regulation of protein ubiquitination (GO:0031397) | 2.82910410 |
| 86 | tRNA aminoacylation (GO:0043039) | 2.82455087 |
| 87 | amino acid activation (GO:0043038) | 2.82455087 |
| 88 | cytochrome complex assembly (GO:0017004) | 2.80358850 |
| 89 | tRNA metabolic process (GO:0006399) | 2.80011466 |
| 90 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.79763381 |
| 91 | regulation of cell cycle arrest (GO:0071156) | 2.79687081 |
| 92 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.79538001 |
| 93 | tRNA aminoacylation for protein translation (GO:0006418) | 2.78095577 |
| 94 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.76920204 |
| 95 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.75325604 |
| 96 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.74760454 |
| 97 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.74760454 |
| 98 | mitochondrial RNA metabolic process (GO:0000959) | 2.74025383 |
| 99 | protein localization to mitochondrion (GO:0070585) | 2.73255999 |
| 100 | GMP metabolic process (GO:0046037) | 2.73078055 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.43114188 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 5.01598530 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.90119874 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.25994188 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.71306559 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.59824110 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.21282960 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.12419429 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.00147050 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.85453291 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.84072731 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.80055211 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.67851747 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.41657992 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.33897642 |
| 16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.23240653 |
| 17 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.22752458 |
| 18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.21165001 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.20747463 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.13168202 |
| 21 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.11401647 |
| 22 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.08084131 |
| 23 | VDR_22108803_ChIP-Seq_LS180_Human | 1.89131228 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.87610420 |
| 25 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.84497868 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.83640603 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.82469658 |
| 28 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.77624180 |
| 29 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.77366841 |
| 30 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.74720672 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.73126400 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.70822686 |
| 33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.69733990 |
| 34 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.67668699 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.59922178 |
| 36 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.55427635 |
| 37 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.55320575 |
| 38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.54531862 |
| 39 | EWS_26573619_Chip-Seq_HEK293_Human | 1.53824930 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.53375258 |
| 41 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.42306327 |
| 42 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.41770940 |
| 43 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.40507032 |
| 44 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.31081555 |
| 45 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.30895059 |
| 46 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.29918842 |
| 47 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.29640965 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.29189660 |
| 49 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.28861867 |
| 50 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.28402999 |
| 51 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28245792 |
| 52 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.27218211 |
| 53 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.26615039 |
| 54 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.24948122 |
| 55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21733022 |
| 56 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.18395551 |
| 57 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.11897302 |
| 58 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.11897302 |
| 59 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.11217429 |
| 60 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.10848460 |
| 61 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.09939759 |
| 62 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.09313835 |
| 63 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.08349149 |
| 64 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.08286792 |
| 65 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06799603 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.04480710 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.04480710 |
| 68 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.01870247 |
| 69 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01194030 |
| 70 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.99872944 |
| 71 | GATA3_26560356_Chip-Seq_TH2_Human | 0.99074529 |
| 72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98912677 |
| 73 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.98115158 |
| 74 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.97775912 |
| 75 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97587879 |
| 76 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.96735186 |
| 77 | P300_19829295_ChIP-Seq_ESCs_Human | 0.95527554 |
| 78 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.94549635 |
| 79 | NCOR_22424771_ChIP-Seq_293T_Human | 0.94219422 |
| 80 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.92723247 |
| 81 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.91035646 |
| 82 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.90388995 |
| 83 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.89903877 |
| 84 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89788840 |
| 85 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.88832871 |
| 86 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.86290099 |
| 87 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.84585557 |
| 88 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.83392599 |
| 89 | FUS_26573619_Chip-Seq_HEK293_Human | 0.82893281 |
| 90 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.82658744 |
| 91 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.81862436 |
| 92 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.81739307 |
| 93 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.79266882 |
| 94 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.76869457 |
| 95 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.76793782 |
| 96 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.75736522 |
| 97 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.75587233 |
| 98 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.74780356 |
| 99 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.74168516 |
| 100 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.74117275 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 3.23185487 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 2.86896148 |
| 3 | MP0005084_abnormal_gallbladder_morpholo | 2.66852315 |
| 4 | MP0005671_abnormal_response_to | 2.60527307 |
| 5 | MP0002163_abnormal_gland_morphology | 2.59372899 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.54899125 |
| 7 | MP0001873_stomach_inflammation | 2.52159584 |
| 8 | MP0008058_abnormal_DNA_repair | 2.37306266 |
| 9 | MP0008872_abnormal_physiological_respon | 2.37115788 |
| 10 | MP0000685_abnormal_immune_system | 2.35486024 |
| 11 | MP0003786_premature_aging | 2.28370565 |
| 12 | MP0003693_abnormal_embryo_hatching | 2.25707638 |
| 13 | MP0005379_endocrine/exocrine_gland_phen | 2.18403736 |
| 14 | MP0003186_abnormal_redox_activity | 2.18171427 |
| 15 | MP0008007_abnormal_cellular_replicative | 2.17388785 |
| 16 | MP0008877_abnormal_DNA_methylation | 2.14315437 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 2.10835328 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 1.99774735 |
| 19 | MP0005167_abnormal_blood-brain_barrier | 1.96080648 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.94813178 |
| 21 | MP0008875_abnormal_xenobiotic_pharmacok | 1.94593551 |
| 22 | MP0003950_abnormal_plasma_membrane | 1.86454407 |
| 23 | MP0004145_abnormal_muscle_electrophysio | 1.81284599 |
| 24 | MP0009333_abnormal_splenocyte_physiolog | 1.81245558 |
| 25 | MP0001790_abnormal_immune_system | 1.78842893 |
| 26 | MP0005387_immune_system_phenotype | 1.78842893 |
| 27 | MP0003718_maternal_effect | 1.78401738 |
| 28 | MP0009785_altered_susceptibility_to | 1.75240839 |
| 29 | MP0002166_altered_tumor_susceptibility | 1.72023907 |
| 30 | MP0006035_abnormal_mitochondrial_morpho | 1.71437470 |
| 31 | MP0003646_muscle_fatigue | 1.71378001 |
| 32 | MP0002876_abnormal_thyroid_physiology | 1.69384112 |
| 33 | MP0005645_abnormal_hypothalamus_physiol | 1.68712096 |
| 34 | MP0003011_delayed_dark_adaptation | 1.65440770 |
| 35 | MP0008775_abnormal_heart_ventricle | 1.62422300 |
| 36 | MP0002837_dystrophic_cardiac_calcinosis | 1.61607040 |
| 37 | MP0001529_abnormal_vocalization | 1.54495971 |
| 38 | MP0010094_abnormal_chromosome_stability | 1.53680089 |
| 39 | MP0004957_abnormal_blastocyst_morpholog | 1.52155929 |
| 40 | MP0002006_tumorigenesis | 1.43410709 |
| 41 | MP0001800_abnormal_humoral_immune | 1.35765035 |
| 42 | MP0004885_abnormal_endolymph | 1.34006549 |
| 43 | MP0005551_abnormal_eye_electrophysiolog | 1.29469789 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.29161229 |
| 45 | MP0004147_increased_porphyrin_level | 1.28056818 |
| 46 | MP0006072_abnormal_retinal_apoptosis | 1.19904714 |
| 47 | MP0009764_decreased_sensitivity_to | 1.19322928 |
| 48 | MP0004142_abnormal_muscle_tone | 1.18831103 |
| 49 | MP0000372_irregular_coat_pigmentation | 1.18431513 |
| 50 | MP0006276_abnormal_autonomic_nervous | 1.18374549 |
| 51 | MP0001348_abnormal_lacrimal_gland | 1.17909591 |
| 52 | MP0001968_abnormal_touch/_nociception | 1.17530654 |
| 53 | MP0003195_calcinosis | 1.15947965 |
| 54 | MP0002736_abnormal_nociception_after | 1.14141546 |
| 55 | MP0006082_CNS_inflammation | 1.13948505 |
| 56 | MP0001501_abnormal_sleep_pattern | 1.10208117 |
| 57 | MP0004782_abnormal_surfactant_physiolog | 1.09608172 |
| 58 | MP0003866_abnormal_defecation | 1.06549640 |
| 59 | MP0005670_abnormal_white_adipose | 1.02983354 |
| 60 | MP0005332_abnormal_amino_acid | 1.01701351 |
| 61 | MP0005000_abnormal_immune_tolerance | 0.95970582 |
| 62 | MP0002723_abnormal_immune_serum | 0.91081629 |
| 63 | MP0000613_abnormal_salivary_gland | 0.90119060 |
| 64 | MP0004215_abnormal_myocardial_fiber | 0.87814309 |
| 65 | MP0002254_reproductive_system_inflammat | 0.87666414 |
| 66 | MP0003567_abnormal_fetal_cardiomyocyte | 0.87426440 |
| 67 | MP0000358_abnormal_cell_content/ | 0.87288698 |
| 68 | MP0002693_abnormal_pancreas_physiology | 0.86053586 |
| 69 | MP0005389_reproductive_system_phenotype | 0.85838637 |
| 70 | MP0009745_abnormal_behavioral_response | 0.85520106 |
| 71 | MP0002751_abnormal_autonomic_nervous | 0.84320283 |
| 72 | MP0002452_abnormal_antigen_presenting | 0.83935647 |
| 73 | MP0001905_abnormal_dopamine_level | 0.83845067 |
| 74 | MP0010386_abnormal_urinary_bladder | 0.83239307 |
| 75 | MP0001984_abnormal_olfaction | 0.82315380 |
| 76 | MP0001502_abnormal_circadian_rhythm | 0.81679661 |
| 77 | MP0002420_abnormal_adaptive_immunity | 0.80800306 |
| 78 | MP0001764_abnormal_homeostasis | 0.80594819 |
| 79 | MP0001819_abnormal_immune_cell | 0.80152505 |
| 80 | MP0005253_abnormal_eye_physiology | 0.78755348 |
| 81 | MP0008873_increased_physiological_sensi | 0.78628829 |
| 82 | MP0005408_hypopigmentation | 0.78416452 |
| 83 | MP0001440_abnormal_grooming_behavior | 0.77261391 |
| 84 | MP0005646_abnormal_pituitary_gland | 0.75808369 |
| 85 | MP0000749_muscle_degeneration | 0.75637911 |
| 86 | MP0001663_abnormal_digestive_system | 0.74687785 |
| 87 | MP0009046_muscle_twitch | 0.74672929 |
| 88 | MP0005636_abnormal_mineral_homeostasis | 0.74301426 |
| 89 | MP0003111_abnormal_nucleus_morphology | 0.74178927 |
| 90 | MP0001986_abnormal_taste_sensitivity | 0.73800308 |
| 91 | MP0005365_abnormal_bile_salt | 0.73778390 |
| 92 | MP0005330_cardiomyopathy | 0.72924776 |
| 93 | MP0004019_abnormal_vitamin_homeostasis | 0.71372295 |
| 94 | MP0001881_abnormal_mammary_gland | 0.71314992 |
| 95 | MP0003077_abnormal_cell_cycle | 0.71094991 |
| 96 | MP0005410_abnormal_fertilization | 0.70966719 |
| 97 | MP0002272_abnormal_nervous_system | 0.70617169 |
| 98 | MP0002938_white_spotting | 0.70253820 |
| 99 | MP0005319_abnormal_enzyme/_coenzyme | 0.68956321 |
| 100 | MP0005165_increased_susceptibility_to | 0.68933282 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.02735857 |
| 2 | Acute encephalopathy (HP:0006846) | 4.42318638 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.30641252 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.30427000 |
| 5 | Increased CSF lactate (HP:0002490) | 4.23800989 |
| 6 | Progressive macrocephaly (HP:0004481) | 4.09593420 |
| 7 | Hepatocellular necrosis (HP:0001404) | 4.02439138 |
| 8 | Hepatic necrosis (HP:0002605) | 3.65951212 |
| 9 | Increased serum lactate (HP:0002151) | 3.61864885 |
| 10 | Cerebral edema (HP:0002181) | 3.28819736 |
| 11 | Hypoproteinemia (HP:0003075) | 3.15830970 |
| 12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.07401109 |
| 13 | Stomatitis (HP:0010280) | 3.03575837 |
| 14 | Optic disc pallor (HP:0000543) | 3.00757575 |
| 15 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.90755716 |
| 16 | Increased serum pyruvate (HP:0003542) | 2.87671704 |
| 17 | Lactic acidosis (HP:0003128) | 2.85134739 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 2.83410852 |
| 19 | Lipid accumulation in hepatocytes (HP:0006561) | 2.79866015 |
| 20 | Abnormality of alanine metabolism (HP:0010916) | 2.79215751 |
| 21 | Hyperalaninemia (HP:0003348) | 2.79215751 |
| 22 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.79215751 |
| 23 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.78759532 |
| 24 | Respiratory failure (HP:0002878) | 2.74239634 |
| 25 | Abnormality of glycolysis (HP:0004366) | 2.72115797 |
| 26 | Abnormality of the anterior horn cell (HP:0006802) | 2.70246901 |
| 27 | Degeneration of anterior horn cells (HP:0002398) | 2.70246901 |
| 28 | Methylmalonic acidemia (HP:0002912) | 2.65529041 |
| 29 | Methylmalonic aciduria (HP:0012120) | 2.64423393 |
| 30 | Exercise intolerance (HP:0003546) | 2.64012668 |
| 31 | IgG deficiency (HP:0004315) | 2.63121546 |
| 32 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.62150828 |
| 33 | Pancreatic cysts (HP:0001737) | 2.56489220 |
| 34 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.45712653 |
| 35 | Abnormality of the pons (HP:0007361) | 2.45158317 |
| 36 | Leukodystrophy (HP:0002415) | 2.44319956 |
| 37 | Abnormality of midbrain morphology (HP:0002418) | 2.38496992 |
| 38 | Molar tooth sign on MRI (HP:0002419) | 2.38496992 |
| 39 | Renal Fanconi syndrome (HP:0001994) | 2.36867159 |
| 40 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.36747510 |
| 41 | Type I transferrin isoform profile (HP:0003642) | 2.36544411 |
| 42 | Oral leukoplakia (HP:0002745) | 2.35610213 |
| 43 | Meckel diverticulum (HP:0002245) | 2.34807609 |
| 44 | Lethargy (HP:0001254) | 2.32304866 |
| 45 | Abnormality of the ileum (HP:0001549) | 2.31145873 |
| 46 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.29780538 |
| 47 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.29780538 |
| 48 | Abnormal protein glycosylation (HP:0012346) | 2.29780538 |
| 49 | Abnormal glycosylation (HP:0012345) | 2.29780538 |
| 50 | CNS demyelination (HP:0007305) | 2.28982421 |
| 51 | Increased IgM level (HP:0003496) | 2.28906704 |
| 52 | Abnormality of the labia minora (HP:0012880) | 2.28801620 |
| 53 | Large for gestational age (HP:0001520) | 2.28482664 |
| 54 | Colon cancer (HP:0003003) | 2.27725661 |
| 55 | Congenital, generalized hypertrichosis (HP:0004540) | 2.22504965 |
| 56 | Exertional dyspnea (HP:0002875) | 2.22503643 |
| 57 | Abnormality of the renal cortex (HP:0011035) | 2.21378737 |
| 58 | Congenital stationary night blindness (HP:0007642) | 2.19660472 |
| 59 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.18375555 |
| 60 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.18375555 |
| 61 | Progressive inability to walk (HP:0002505) | 2.18365811 |
| 62 | Dyschromatopsia (HP:0007641) | 2.15560706 |
| 63 | Cerebral hypomyelination (HP:0006808) | 2.15320094 |
| 64 | Abnormality of methionine metabolism (HP:0010901) | 2.15104083 |
| 65 | Hypoplasia of the uterus (HP:0000013) | 2.12902662 |
| 66 | Constricted visual fields (HP:0001133) | 2.12382023 |
| 67 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.09119988 |
| 68 | Abolished electroretinogram (ERG) (HP:0000550) | 2.04892210 |
| 69 | Pancytopenia (HP:0001876) | 2.04232358 |
| 70 | Hypoplasia of the pons (HP:0012110) | 1.98712098 |
| 71 | Inability to walk (HP:0002540) | 1.97812774 |
| 72 | Cerebral hemorrhage (HP:0001342) | 1.97616941 |
| 73 | Delayed CNS myelination (HP:0002188) | 1.92214710 |
| 74 | X-linked dominant inheritance (HP:0001423) | 1.92081544 |
| 75 | Horseshoe kidney (HP:0000085) | 1.91683250 |
| 76 | Nephronophthisis (HP:0000090) | 1.87750267 |
| 77 | Increased corneal curvature (HP:0100692) | 1.87606412 |
| 78 | Keratoconus (HP:0000563) | 1.87606412 |
| 79 | Polyuria (HP:0000103) | 1.85738083 |
| 80 | Abnormality of serum amino acid levels (HP:0003112) | 1.82830112 |
| 81 | Abnormality of the renal medulla (HP:0100957) | 1.82783766 |
| 82 | Pendular nystagmus (HP:0012043) | 1.82473180 |
| 83 | Rough bone trabeculation (HP:0100670) | 1.80273715 |
| 84 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.80104858 |
| 85 | True hermaphroditism (HP:0010459) | 1.80005774 |
| 86 | Oligodactyly (hands) (HP:0001180) | 1.79755652 |
| 87 | Intestinal atresia (HP:0011100) | 1.79641102 |
| 88 | Neutropenia (HP:0001875) | 1.78868334 |
| 89 | Duodenal stenosis (HP:0100867) | 1.75751578 |
| 90 | Small intestinal stenosis (HP:0012848) | 1.75751578 |
| 91 | Alkalosis (HP:0001948) | 1.66745172 |
| 92 | Chronic diarrhea (HP:0002028) | 1.66551775 |
| 93 | Abnormality of T cell physiology (HP:0011840) | 1.66488627 |
| 94 | Glycosuria (HP:0003076) | 1.66048416 |
| 95 | Abnormality of urine glucose concentration (HP:0011016) | 1.66048416 |
| 96 | Reduced antithrombin III activity (HP:0001976) | 1.62866257 |
| 97 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.62706652 |
| 98 | Duplicated collecting system (HP:0000081) | 1.62136238 |
| 99 | CNS hypomyelination (HP:0003429) | 1.62092259 |
| 100 | Hypokalemic alkalosis (HP:0001949) | 1.62039726 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.91474212 |
| 2 | TIE1 | 3.70905378 |
| 3 | NUAK1 | 3.35477367 |
| 4 | TSSK6 | 3.34554799 |
| 5 | MST4 | 3.08683345 |
| 6 | BUB1 | 3.02751908 |
| 7 | EIF2AK3 | 2.85450975 |
| 8 | EIF2AK1 | 2.30124674 |
| 9 | GRK1 | 2.27364383 |
| 10 | VRK1 | 2.26360343 |
| 11 | SRPK1 | 2.21417151 |
| 12 | TAF1 | 2.18656119 |
| 13 | TRIM28 | 2.06529076 |
| 14 | TLK1 | 1.98497148 |
| 15 | PLK3 | 1.91849978 |
| 16 | MAP2K6 | 1.90925913 |
| 17 | ZAK | 1.87606199 |
| 18 | NEK1 | 1.83043327 |
| 19 | NME1 | 1.75177073 |
| 20 | ADRBK2 | 1.70718317 |
| 21 | PDK2 | 1.62258521 |
| 22 | TXK | 1.61507521 |
| 23 | BCKDK | 1.54852880 |
| 24 | PBK | 1.50145495 |
| 25 | DAPK1 | 1.44586376 |
| 26 | MAP3K12 | 1.39717366 |
| 27 | MAP4K2 | 1.33569937 |
| 28 | CSNK1G3 | 1.31758316 |
| 29 | MAPKAPK3 | 1.21739548 |
| 30 | TEC | 1.20887496 |
| 31 | CSNK1A1L | 1.19753879 |
| 32 | CSNK1G1 | 1.18707683 |
| 33 | BCR | 1.17828991 |
| 34 | STK16 | 1.13133481 |
| 35 | WNK4 | 1.13038961 |
| 36 | PLK2 | 1.08655141 |
| 37 | FES | 1.08634257 |
| 38 | EIF2AK2 | 1.06349659 |
| 39 | CSNK1G2 | 1.05723019 |
| 40 | STK39 | 1.03123725 |
| 41 | OXSR1 | 1.02551762 |
| 42 | PINK1 | 0.99261063 |
| 43 | DYRK2 | 0.98234387 |
| 44 | BMPR1B | 0.91640804 |
| 45 | GRK5 | 0.89202081 |
| 46 | TAOK3 | 0.87460759 |
| 47 | LIMK1 | 0.84478574 |
| 48 | FRK | 0.84164254 |
| 49 | IKBKB | 0.83215483 |
| 50 | INSRR | 0.82735425 |
| 51 | PASK | 0.81172930 |
| 52 | MYLK | 0.80332138 |
| 53 | PHKG1 | 0.78474354 |
| 54 | PHKG2 | 0.78474354 |
| 55 | KIT | 0.77549091 |
| 56 | FER | 0.72072839 |
| 57 | PIK3CG | 0.70907796 |
| 58 | TGFBR1 | 0.68099607 |
| 59 | CCNB1 | 0.67533434 |
| 60 | PTK2B | 0.64169697 |
| 61 | MKNK2 | 0.63657216 |
| 62 | MAPKAPK5 | 0.61540448 |
| 63 | MKNK1 | 0.54134452 |
| 64 | PRKCI | 0.49497969 |
| 65 | WNK3 | 0.49198845 |
| 66 | CDK8 | 0.48729335 |
| 67 | ATR | 0.48061639 |
| 68 | SMG1 | 0.46051457 |
| 69 | NME2 | 0.45158329 |
| 70 | PRKCQ | 0.44989409 |
| 71 | PRKCG | 0.44575650 |
| 72 | PLK1 | 0.44463904 |
| 73 | BRSK1 | 0.43943906 |
| 74 | TGFBR2 | 0.43687979 |
| 75 | SIK3 | 0.42734863 |
| 76 | PRKCE | 0.41616411 |
| 77 | ALK | 0.40430355 |
| 78 | STK38L | 0.39344109 |
| 79 | TTK | 0.38057647 |
| 80 | DAPK3 | 0.37939068 |
| 81 | NLK | 0.37441183 |
| 82 | ILK | 0.35751789 |
| 83 | AURKB | 0.35540740 |
| 84 | CSNK2A1 | 0.34352543 |
| 85 | MAP4K1 | 0.33620360 |
| 86 | ITK | 0.33332906 |
| 87 | CSNK1A1 | 0.32692989 |
| 88 | PAK3 | 0.29994902 |
| 89 | MAPK13 | 0.29638067 |
| 90 | PAK4 | 0.29524082 |
| 91 | RPS6KA5 | 0.25992200 |
| 92 | PIK3CA | 0.25474405 |
| 93 | CAMK2A | 0.25172790 |
| 94 | IGF1R | 0.24701214 |
| 95 | WEE1 | 0.24628930 |
| 96 | DAPK2 | 0.24622774 |
| 97 | CASK | 0.23742261 |
| 98 | NEK2 | 0.23389633 |
| 99 | TNIK | 0.22960684 |
| 100 | PRKG1 | 0.22506924 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.84080404 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.38780492 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.99949883 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.88781223 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.85399991 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.44401606 |
| 7 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.92736194 |
| 8 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.90040522 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 1.80950560 |
| 10 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.77191555 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.73354142 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 1.66421579 |
| 13 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.66057899 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.58159311 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.57546522 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.52044970 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.51935979 |
| 18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.51896746 |
| 19 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.50566153 |
| 20 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.49797024 |
| 21 | Ribosome_Homo sapiens_hsa03010 | 1.47535962 |
| 22 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.46005628 |
| 23 | RNA transport_Homo sapiens_hsa03013 | 1.43913601 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.41707240 |
| 25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.39946801 |
| 26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.39789221 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.36550970 |
| 28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.36336587 |
| 29 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.35452102 |
| 30 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.32603454 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.31528890 |
| 32 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.31502061 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.28432115 |
| 34 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.28389324 |
| 35 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.25285318 |
| 36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.24198360 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.23366248 |
| 38 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.23090018 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 1.20256758 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.15821969 |
| 41 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15753558 |
| 42 | Asthma_Homo sapiens_hsa05310 | 1.14894863 |
| 43 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.14302485 |
| 44 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.09682037 |
| 45 | Base excision repair_Homo sapiens_hsa03410 | 1.06699884 |
| 46 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.06515748 |
| 47 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.05395475 |
| 48 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.04910933 |
| 49 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.03678447 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.01332250 |
| 51 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.97028525 |
| 52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.96874309 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.96870798 |
| 54 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.96677549 |
| 55 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.94767993 |
| 56 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.94130453 |
| 57 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.93361063 |
| 58 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.93340515 |
| 59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.90992780 |
| 60 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.87654810 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 0.87412610 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.81541687 |
| 63 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.81289094 |
| 64 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.77943422 |
| 65 | Carbon metabolism_Homo sapiens_hsa01200 | 0.76811097 |
| 66 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.75385004 |
| 67 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.75201119 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71905987 |
| 69 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.67490936 |
| 70 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.66814798 |
| 71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.65585214 |
| 72 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.64772701 |
| 73 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.63541335 |
| 74 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.63134422 |
| 75 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62121832 |
| 76 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59791049 |
| 77 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.59583007 |
| 78 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.57839041 |
| 79 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.53423006 |
| 80 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.52377436 |
| 81 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.52233746 |
| 82 | Sulfur relay system_Homo sapiens_hsa04122 | 0.51370046 |
| 83 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47983701 |
| 84 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.46644187 |
| 85 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.46456431 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44975756 |
| 87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43308388 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.39177503 |
| 89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.39138696 |
| 90 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.37775592 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36850647 |
| 92 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.36264246 |
| 93 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36203254 |
| 94 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.36027408 |
| 95 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35337000 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.35041864 |
| 97 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.34537153 |
| 98 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.32153505 |
| 99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.31850332 |
| 100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27108888 |

