

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.32470212 |
| 2 | cytidine metabolic process (GO:0046087) | 7.01491316 |
| 3 | cytidine catabolic process (GO:0006216) | 7.01491316 |
| 4 | cytidine deamination (GO:0009972) | 7.01491316 |
| 5 | eosinophil chemotaxis (GO:0048245) | 6.78349270 |
| 6 | protein prenylation (GO:0018342) | 6.38372728 |
| 7 | prenylation (GO:0097354) | 6.38372728 |
| 8 | eosinophil migration (GO:0072677) | 6.11835916 |
| 9 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.95310756 |
| 10 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.90035060 |
| 11 | fucose catabolic process (GO:0019317) | 5.64276385 |
| 12 | L-fucose metabolic process (GO:0042354) | 5.64276385 |
| 13 | L-fucose catabolic process (GO:0042355) | 5.64276385 |
| 14 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 5.32071501 |
| 15 | negative regulation of Ras GTPase activity (GO:0034261) | 5.07694948 |
| 16 | proteasome assembly (GO:0043248) | 4.79125950 |
| 17 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 4.69495680 |
| 18 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 4.69495680 |
| 19 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 4.69495680 |
| 20 | ribosomal small subunit assembly (GO:0000028) | 4.46774115 |
| 21 | macrophage chemotaxis (GO:0048246) | 4.35063448 |
| 22 | regulation of mononuclear cell migration (GO:0071675) | 4.34278807 |
| 23 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 4.31362474 |
| 24 | protein deneddylation (GO:0000338) | 4.00646053 |
| 25 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.96679864 |
| 26 | chaperone-mediated protein transport (GO:0072321) | 3.92775447 |
| 27 | DNA demethylation (GO:0080111) | 3.89897119 |
| 28 | cullin deneddylation (GO:0010388) | 3.88951178 |
| 29 | protein neddylation (GO:0045116) | 3.81559065 |
| 30 | positive regulation of growth hormone secretion (GO:0060124) | 3.81244664 |
| 31 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.73799683 |
| 32 | localization within membrane (GO:0051668) | 3.73595558 |
| 33 | iron-sulfur cluster assembly (GO:0016226) | 3.70000431 |
| 34 | metallo-sulfur cluster assembly (GO:0031163) | 3.70000431 |
| 35 | vesicle fusion (GO:0006906) | 3.69015333 |
| 36 | ATP synthesis coupled proton transport (GO:0015986) | 3.68854092 |
| 37 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.68854092 |
| 38 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.68551401 |
| 39 | branch elongation of an epithelium (GO:0060602) | 3.66098733 |
| 40 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.62930474 |
| 41 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.56499459 |
| 42 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.48146571 |
| 43 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.48146571 |
| 44 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.47327063 |
| 45 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.47327063 |
| 46 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.47327063 |
| 47 | regulation of timing of cell differentiation (GO:0048505) | 3.45960618 |
| 48 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.40916643 |
| 49 | coenzyme A biosynthetic process (GO:0015937) | 3.37832494 |
| 50 | regulation of sister chromatid cohesion (GO:0007063) | 3.35091873 |
| 51 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 3.31459402 |
| 52 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.29050926 |
| 53 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.29050926 |
| 54 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.27700852 |
| 55 | termination of RNA polymerase III transcription (GO:0006386) | 3.27700852 |
| 56 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.26858805 |
| 57 | regulation of development, heterochronic (GO:0040034) | 3.25923272 |
| 58 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.25736030 |
| 59 | monocyte chemotaxis (GO:0002548) | 3.25165302 |
| 60 | spinal cord association neuron differentiation (GO:0021527) | 3.24169733 |
| 61 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.23453211 |
| 62 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.23453211 |
| 63 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.22859583 |
| 64 | autophagic vacuole fusion (GO:0000046) | 3.21360695 |
| 65 | forebrain neuron differentiation (GO:0021879) | 3.14560157 |
| 66 | DNA dealkylation (GO:0035510) | 3.12721428 |
| 67 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.11878367 |
| 68 | negative regulation of ligase activity (GO:0051352) | 3.11878367 |
| 69 | positive regulation of calcium ion import (GO:0090280) | 3.10856040 |
| 70 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.10174638 |
| 71 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.06364788 |
| 72 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.05198137 |
| 73 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.04876488 |
| 74 | ganglion development (GO:0061548) | 3.03548855 |
| 75 | membrane budding (GO:0006900) | 2.95756038 |
| 76 | intracellular protein transmembrane import (GO:0044743) | 2.93412915 |
| 77 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 2.90852812 |
| 78 | platelet dense granule organization (GO:0060155) | 2.89005335 |
| 79 | cerebral cortex neuron differentiation (GO:0021895) | 2.87931458 |
| 80 | olfactory bulb development (GO:0021772) | 2.86311922 |
| 81 | growth hormone secretion (GO:0030252) | 2.85863318 |
| 82 | organ growth (GO:0035265) | 2.85696432 |
| 83 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.85224453 |
| 84 | positive regulation of cell cycle arrest (GO:0071158) | 2.84230145 |
| 85 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.80486094 |
| 86 | negative regulation by host of viral transcription (GO:0043922) | 2.77433199 |
| 87 | acrosome assembly (GO:0001675) | 2.74741603 |
| 88 | organelle membrane fusion (GO:0090174) | 2.72803086 |
| 89 | respiratory electron transport chain (GO:0022904) | 2.72512843 |
| 90 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.72462851 |
| 91 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.72051402 |
| 92 | electron transport chain (GO:0022900) | 2.69773613 |
| 93 | GPI anchor biosynthetic process (GO:0006506) | 2.69619916 |
| 94 | GPI anchor metabolic process (GO:0006505) | 2.69178856 |
| 95 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.68284670 |
| 96 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.66680657 |
| 97 | protein complex biogenesis (GO:0070271) | 2.66144326 |
| 98 | oxidative demethylation (GO:0070989) | 2.66116200 |
| 99 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 2.63337547 |
| 100 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.62322314 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.15222219 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 4.45093452 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.11273000 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.69751589 |
| 5 | GATA1_22025678_ChIP-Seq_K562_Human | 3.68158103 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.21016150 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.15506934 |
| 8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.13927495 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.90960804 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.67959756 |
| 11 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.57035942 |
| 12 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.56777760 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.40039186 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.30911742 |
| 15 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.28099164 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.25022513 |
| 17 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.21474830 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.19770332 |
| 19 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.18579035 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.16988303 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.05063435 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.82808837 |
| 23 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.77867469 |
| 24 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.68313329 |
| 25 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.67036693 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.66231072 |
| 27 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.66036810 |
| 28 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.65153316 |
| 29 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.62578218 |
| 30 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.62068324 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.59567668 |
| 32 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.57249254 |
| 33 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.47659892 |
| 34 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.46656684 |
| 35 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.45413994 |
| 36 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.44806017 |
| 37 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.41703119 |
| 38 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37619025 |
| 39 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.36024799 |
| 40 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.31600291 |
| 41 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.29579524 |
| 42 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.29365479 |
| 43 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.27876536 |
| 44 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.25450047 |
| 45 | FUS_26573619_Chip-Seq_HEK293_Human | 1.24850662 |
| 46 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.23388004 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.22210162 |
| 48 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.18373459 |
| 49 | P300_19829295_ChIP-Seq_ESCs_Human | 1.14815712 |
| 50 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.13210761 |
| 51 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.07911878 |
| 52 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07634332 |
| 53 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.07546554 |
| 54 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07546554 |
| 55 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.06319845 |
| 56 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.06319845 |
| 57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.05270317 |
| 58 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.04147977 |
| 59 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.03892009 |
| 60 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02902146 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02902146 |
| 62 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.01907552 |
| 63 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.01854209 |
| 64 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.01672892 |
| 65 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.01115031 |
| 66 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.99755015 |
| 67 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.99590994 |
| 68 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.99590994 |
| 69 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.99590994 |
| 70 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98828381 |
| 71 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97236618 |
| 72 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97236618 |
| 73 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.96619756 |
| 74 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.95778470 |
| 75 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.95172526 |
| 76 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.94759481 |
| 77 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94414036 |
| 78 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.94303454 |
| 79 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.92313158 |
| 80 | AR_20517297_ChIP-Seq_VCAP_Human | 0.91585880 |
| 81 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.89792874 |
| 82 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.89509156 |
| 83 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.89096931 |
| 84 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88829427 |
| 85 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.88584291 |
| 86 | GATA3_26560356_Chip-Seq_TH1_Human | 0.88079537 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.87777608 |
| 88 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.86788807 |
| 89 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85683178 |
| 90 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.85385780 |
| 91 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.85298722 |
| 92 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.84643938 |
| 93 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.84563877 |
| 94 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.83048743 |
| 95 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.82444327 |
| 96 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.82422161 |
| 97 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.81082001 |
| 98 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.79058203 |
| 99 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.77868433 |
| 100 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.77375615 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 6.03477686 |
| 2 | MP0002822_catalepsy | 4.85539025 |
| 3 | MP0008789_abnormal_olfactory_epithelium | 3.45176698 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 3.28421034 |
| 5 | MP0002102_abnormal_ear_morphology | 3.03181655 |
| 6 | MP0006082_CNS_inflammation | 2.77521133 |
| 7 | MP0005499_abnormal_olfactory_system | 2.65651204 |
| 8 | MP0005394_taste/olfaction_phenotype | 2.65651204 |
| 9 | MP0002751_abnormal_autonomic_nervous | 2.58999042 |
| 10 | MP0003303_peritoneal_inflammation | 2.45520823 |
| 11 | MP0005671_abnormal_response_to | 2.24867265 |
| 12 | MP0001529_abnormal_vocalization | 2.14177545 |
| 13 | MP0001919_abnormal_reproductive_system | 2.11123526 |
| 14 | MP0002876_abnormal_thyroid_physiology | 2.07642807 |
| 15 | MP0000372_irregular_coat_pigmentation | 2.04595924 |
| 16 | MP0001664_abnormal_digestion | 1.91450681 |
| 17 | MP0005645_abnormal_hypothalamus_physiol | 1.86924887 |
| 18 | MP0005253_abnormal_eye_physiology | 1.83322937 |
| 19 | MP0004145_abnormal_muscle_electrophysio | 1.81502666 |
| 20 | MP0006276_abnormal_autonomic_nervous | 1.80487303 |
| 21 | MP0001905_abnormal_dopamine_level | 1.72551084 |
| 22 | MP0002095_abnormal_skin_pigmentation | 1.57485879 |
| 23 | MP0002163_abnormal_gland_morphology | 1.56624091 |
| 24 | MP0005389_reproductive_system_phenotype | 1.55946628 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.53138688 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.50779844 |
| 27 | MP0002638_abnormal_pupillary_reflex | 1.45477603 |
| 28 | MP0003880_abnormal_central_pattern | 1.41690470 |
| 29 | MP0009745_abnormal_behavioral_response | 1.40960138 |
| 30 | MP0001984_abnormal_olfaction | 1.40321856 |
| 31 | MP0008872_abnormal_physiological_respon | 1.36632309 |
| 32 | MP0006292_abnormal_olfactory_placode | 1.35737376 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.33511010 |
| 34 | MP0001663_abnormal_digestive_system | 1.30340428 |
| 35 | MP0002837_dystrophic_cardiac_calcinosis | 1.28632736 |
| 36 | MP0004270_analgesia | 1.27459555 |
| 37 | MP0005084_abnormal_gallbladder_morpholo | 1.23327882 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.21384018 |
| 39 | MP0000049_abnormal_middle_ear | 1.19063205 |
| 40 | MP0002234_abnormal_pharynx_morphology | 1.17459295 |
| 41 | MP0008875_abnormal_xenobiotic_pharmacok | 1.17424836 |
| 42 | MP0002736_abnormal_nociception_after | 1.17327698 |
| 43 | MP0004147_increased_porphyrin_level | 1.16629392 |
| 44 | MP0004142_abnormal_muscle_tone | 1.16413986 |
| 45 | MP0001188_hyperpigmentation | 1.15759769 |
| 46 | MP0003786_premature_aging | 1.15409515 |
| 47 | MP0008877_abnormal_DNA_methylation | 1.13816181 |
| 48 | MP0005423_abnormal_somatic_nervous | 1.10862344 |
| 49 | MP0003011_delayed_dark_adaptation | 1.10067873 |
| 50 | MP0009785_altered_susceptibility_to | 1.05994504 |
| 51 | MP0003763_abnormal_thymus_physiology | 1.05538958 |
| 52 | MP0003646_muscle_fatigue | 1.04467949 |
| 53 | MP0002734_abnormal_mechanical_nocicepti | 1.01431071 |
| 54 | MP0003937_abnormal_limbs/digits/tail_de | 0.99975140 |
| 55 | MP0002733_abnormal_thermal_nociception | 0.99000843 |
| 56 | MP0002735_abnormal_chemical_nociception | 0.97886466 |
| 57 | MP0004885_abnormal_endolymph | 0.96315279 |
| 58 | MP0001293_anophthalmia | 0.93782334 |
| 59 | MP0002277_abnormal_respiratory_mucosa | 0.93396233 |
| 60 | MP0005379_endocrine/exocrine_gland_phen | 0.91766723 |
| 61 | MP0002272_abnormal_nervous_system | 0.89995188 |
| 62 | MP0005377_hearing/vestibular/ear_phenot | 0.89357922 |
| 63 | MP0003878_abnormal_ear_physiology | 0.89357922 |
| 64 | MP0000467_abnormal_esophagus_morphology | 0.89254680 |
| 65 | MP0001970_abnormal_pain_threshold | 0.87443223 |
| 66 | MP0000631_abnormal_neuroendocrine_gland | 0.87243688 |
| 67 | MP0002184_abnormal_innervation | 0.86338669 |
| 68 | MP0005381_digestive/alimentary_phenotyp | 0.86191659 |
| 69 | MP0005386_behavior/neurological_phenoty | 0.85222446 |
| 70 | MP0004924_abnormal_behavior | 0.85222446 |
| 71 | MP0001501_abnormal_sleep_pattern | 0.84349445 |
| 72 | MP0005083_abnormal_biliary_tract | 0.83036566 |
| 73 | MP0001485_abnormal_pinna_reflex | 0.81523891 |
| 74 | MP0002653_abnormal_ependyma_morphology | 0.79564089 |
| 75 | MP0002752_abnormal_somatic_nervous | 0.78508199 |
| 76 | MP0002909_abnormal_adrenal_gland | 0.76718559 |
| 77 | MP0000026_abnormal_inner_ear | 0.76371280 |
| 78 | MP0008058_abnormal_DNA_repair | 0.76096209 |
| 79 | MP0009046_muscle_twitch | 0.75594106 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.75312769 |
| 81 | MP0008995_early_reproductive_senescence | 0.75077622 |
| 82 | MP0002557_abnormal_social/conspecific_i | 0.73591385 |
| 83 | MP0003787_abnormal_imprinting | 0.73382615 |
| 84 | MP0002210_abnormal_sex_determination | 0.72140531 |
| 85 | MP0001963_abnormal_hearing_physiology | 0.70479161 |
| 86 | MP0002572_abnormal_emotion/affect_behav | 0.70317762 |
| 87 | MP0009333_abnormal_splenocyte_physiolog | 0.70252867 |
| 88 | MP0001764_abnormal_homeostasis | 0.70213638 |
| 89 | MP0005391_vision/eye_phenotype | 0.69280848 |
| 90 | MP0003866_abnormal_defecation | 0.68885080 |
| 91 | MP0003195_calcinosis | 0.68815751 |
| 92 | MP0001873_stomach_inflammation | 0.68361263 |
| 93 | MP0005167_abnormal_blood-brain_barrier | 0.66705200 |
| 94 | MP0005166_decreased_susceptibility_to | 0.65725975 |
| 95 | MP0004742_abnormal_vestibular_system | 0.63780944 |
| 96 | MP0001486_abnormal_startle_reflex | 0.63264086 |
| 97 | MP0003635_abnormal_synaptic_transmissio | 0.63046638 |
| 98 | MP0000778_abnormal_nervous_system | 0.62605288 |
| 99 | MP0002233_abnormal_nose_morphology | 0.59546079 |
| 100 | MP0008775_abnormal_heart_ventricle | 0.58875447 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 4.76441556 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.00018551 |
| 3 | Mitochondrial inheritance (HP:0001427) | 3.76045416 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.60181796 |
| 5 | Abnormality of the renal collecting system (HP:0004742) | 3.55568439 |
| 6 | Duplicated collecting system (HP:0000081) | 3.49631891 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.45595983 |
| 8 | Adactyly (HP:0009776) | 3.45537775 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.36009038 |
| 10 | Acute encephalopathy (HP:0006846) | 3.29221991 |
| 11 | Large for gestational age (HP:0001520) | 3.28005302 |
| 12 | Increased CSF lactate (HP:0002490) | 3.20448079 |
| 13 | Aplastic anemia (HP:0001915) | 3.14661776 |
| 14 | Hepatic necrosis (HP:0002605) | 3.10417366 |
| 15 | Severe muscular hypotonia (HP:0006829) | 3.01355022 |
| 16 | Brushfield spots (HP:0001088) | 2.90146317 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 2.89080008 |
| 18 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.88684422 |
| 19 | Lactic acidosis (HP:0003128) | 2.79692142 |
| 20 | Hypoproteinemia (HP:0003075) | 2.73887237 |
| 21 | Palpebral edema (HP:0100540) | 2.73756793 |
| 22 | Broad-based gait (HP:0002136) | 2.60804938 |
| 23 | IgG deficiency (HP:0004315) | 2.60294613 |
| 24 | Pancreatic cysts (HP:0001737) | 2.60267264 |
| 25 | Hypoplastic pelvis (HP:0008839) | 2.60103804 |
| 26 | Autoamputation (HP:0001218) | 2.59210545 |
| 27 | Increased serum lactate (HP:0002151) | 2.58989304 |
| 28 | Ureteral stenosis (HP:0000071) | 2.57802474 |
| 29 | Molar tooth sign on MRI (HP:0002419) | 2.53386671 |
| 30 | Abnormality of midbrain morphology (HP:0002418) | 2.53386671 |
| 31 | Increased hepatocellular lipid droplets (HP:0006565) | 2.48603898 |
| 32 | Long foot (HP:0001833) | 2.47366195 |
| 33 | True hermaphroditism (HP:0010459) | 2.47356587 |
| 34 | Pancreatic fibrosis (HP:0100732) | 2.45147941 |
| 35 | Cerebral edema (HP:0002181) | 2.45025407 |
| 36 | Dry hair (HP:0011359) | 2.34561138 |
| 37 | Congenital stationary night blindness (HP:0007642) | 2.31321375 |
| 38 | Abolished electroretinogram (ERG) (HP:0000550) | 2.31157756 |
| 39 | Exercise intolerance (HP:0003546) | 2.30875951 |
| 40 | Ureteral obstruction (HP:0006000) | 2.30509409 |
| 41 | Acute lymphatic leukemia (HP:0006721) | 2.30347102 |
| 42 | Optic disc pallor (HP:0000543) | 2.29103299 |
| 43 | Delayed CNS myelination (HP:0002188) | 2.25678316 |
| 44 | Renal Fanconi syndrome (HP:0001994) | 2.24600516 |
| 45 | Lipid accumulation in hepatocytes (HP:0006561) | 2.22885238 |
| 46 | CNS demyelination (HP:0007305) | 2.19328063 |
| 47 | Renal cortical cysts (HP:0000803) | 2.18836854 |
| 48 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.17455490 |
| 49 | Severe combined immunodeficiency (HP:0004430) | 2.17183380 |
| 50 | Methylmalonic acidemia (HP:0002912) | 2.15396118 |
| 51 | Menstrual irregularities (HP:0000858) | 2.14614690 |
| 52 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.13616882 |
| 53 | Respiratory failure (HP:0002878) | 2.13311890 |
| 54 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.12876784 |
| 55 | Increased intramyocellular lipid droplets (HP:0012240) | 2.12109458 |
| 56 | T lymphocytopenia (HP:0005403) | 2.10743027 |
| 57 | Thyroiditis (HP:0100646) | 2.09819137 |
| 58 | Type 2 muscle fiber atrophy (HP:0003554) | 2.09566028 |
| 59 | Progressive muscle weakness (HP:0003323) | 2.08463824 |
| 60 | Abnormality of the renal cortex (HP:0011035) | 2.08298635 |
| 61 | Anhidrosis (HP:0000970) | 2.07498485 |
| 62 | Methylmalonic aciduria (HP:0012120) | 2.05662089 |
| 63 | Abnormality of T cell number (HP:0011839) | 2.05027034 |
| 64 | Decreased muscle mass (HP:0003199) | 2.02036571 |
| 65 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.01989947 |
| 66 | Increased IgM level (HP:0003496) | 1.95277520 |
| 67 | Chorioretinal coloboma (HP:0000567) | 1.94638457 |
| 68 | Anxiety (HP:0000739) | 1.93815528 |
| 69 | Medial flaring of the eyebrow (HP:0010747) | 1.91150594 |
| 70 | Nephronophthisis (HP:0000090) | 1.90431307 |
| 71 | Emotional lability (HP:0000712) | 1.87538648 |
| 72 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.84183894 |
| 73 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.84183894 |
| 74 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.83465683 |
| 75 | Abnormality of the prostate (HP:0008775) | 1.79348103 |
| 76 | Myoglobinuria (HP:0002913) | 1.78926807 |
| 77 | Hypomagnesemia (HP:0002917) | 1.77302330 |
| 78 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.76626457 |
| 79 | Stenosis of the external auditory canal (HP:0000402) | 1.76384969 |
| 80 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.75188229 |
| 81 | Abnormality of alanine metabolism (HP:0010916) | 1.75188229 |
| 82 | Hyperalaninemia (HP:0003348) | 1.75188229 |
| 83 | Hypoplastic nipples (HP:0002557) | 1.73901249 |
| 84 | Hypoalbuminemia (HP:0003073) | 1.73681187 |
| 85 | Abnormal albumin level (HP:0012116) | 1.73681187 |
| 86 | Cerebral hypomyelination (HP:0006808) | 1.73391771 |
| 87 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.73368923 |
| 88 | Lethargy (HP:0001254) | 1.73157162 |
| 89 | Rhabdomyolysis (HP:0003201) | 1.72980765 |
| 90 | Abnormality of the labia minora (HP:0012880) | 1.71900594 |
| 91 | Polydipsia (HP:0001959) | 1.70964976 |
| 92 | Abnormal drinking behavior (HP:0030082) | 1.70964976 |
| 93 | Gait imbalance (HP:0002141) | 1.70935005 |
| 94 | Attenuation of retinal blood vessels (HP:0007843) | 1.68141603 |
| 95 | Pendular nystagmus (HP:0012043) | 1.68064177 |
| 96 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.66714274 |
| 97 | Muscle fiber atrophy (HP:0100295) | 1.64878068 |
| 98 | Colon cancer (HP:0003003) | 1.64484237 |
| 99 | Decreased lacrimation (HP:0000633) | 1.63758548 |
| 100 | Sudden death (HP:0001699) | 1.63090068 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MKNK2 | 7.82298020 |
| 2 | MKNK1 | 4.68646620 |
| 3 | TAOK2 | 3.02598088 |
| 4 | TAOK1 | 2.95128559 |
| 5 | MAP3K11 | 2.80402961 |
| 6 | TXK | 2.56354288 |
| 7 | KDR | 2.22107820 |
| 8 | TESK2 | 2.16253298 |
| 9 | VRK2 | 1.99323442 |
| 10 | MAP3K3 | 1.93551454 |
| 11 | SRPK1 | 1.83922026 |
| 12 | BCKDK | 1.83152337 |
| 13 | MAP4K2 | 1.74123545 |
| 14 | TESK1 | 1.64019904 |
| 15 | ABL2 | 1.63487757 |
| 16 | TRIM28 | 1.58321610 |
| 17 | JAK3 | 1.53012052 |
| 18 | ZAK | 1.51528970 |
| 19 | ADRBK2 | 1.49548138 |
| 20 | MAP2K3 | 1.47224337 |
| 21 | NUAK1 | 1.40690541 |
| 22 | INSRR | 1.40045057 |
| 23 | DYRK1A | 1.39616911 |
| 24 | TIE1 | 1.36665725 |
| 25 | MST4 | 1.35404895 |
| 26 | LIMK1 | 1.29437974 |
| 27 | PHKG2 | 1.28888738 |
| 28 | PHKG1 | 1.28888738 |
| 29 | GRK1 | 1.25279459 |
| 30 | FRK | 1.17515007 |
| 31 | DYRK2 | 1.14936952 |
| 32 | TLK1 | 1.14431226 |
| 33 | BUB1 | 1.14424536 |
| 34 | MAP3K5 | 1.13587281 |
| 35 | MAP3K12 | 1.13365136 |
| 36 | VRK1 | 1.08325892 |
| 37 | BMPR1B | 1.05222426 |
| 38 | WNK3 | 0.98995578 |
| 39 | WNK4 | 0.94466245 |
| 40 | CSNK1G2 | 0.91131792 |
| 41 | CSNK1G3 | 0.86308680 |
| 42 | ITK | 0.84478439 |
| 43 | BCR | 0.83500026 |
| 44 | PRKCQ | 0.79419437 |
| 45 | STK16 | 0.76318182 |
| 46 | MARK1 | 0.73955887 |
| 47 | MAPK13 | 0.73943333 |
| 48 | CSNK1G1 | 0.73476861 |
| 49 | PAK6 | 0.68610405 |
| 50 | EIF2AK3 | 0.66764290 |
| 51 | MAP2K7 | 0.65727491 |
| 52 | DAPK1 | 0.63833566 |
| 53 | MUSK | 0.63589704 |
| 54 | OXSR1 | 0.62272621 |
| 55 | TAOK3 | 0.61857859 |
| 56 | PLK2 | 0.61232505 |
| 57 | MAP2K6 | 0.60121367 |
| 58 | TSSK6 | 0.60092291 |
| 59 | CSNK1A1L | 0.60090182 |
| 60 | AURKA | 0.59122263 |
| 61 | CHEK2 | 0.58387328 |
| 62 | PINK1 | 0.57310634 |
| 63 | OBSCN | 0.50509657 |
| 64 | PRKCE | 0.49421994 |
| 65 | CSNK1A1 | 0.49160127 |
| 66 | DAPK2 | 0.49157807 |
| 67 | FGFR2 | 0.48796612 |
| 68 | STK39 | 0.48258029 |
| 69 | CASK | 0.47642240 |
| 70 | TEC | 0.47056332 |
| 71 | MINK1 | 0.46638751 |
| 72 | LMTK2 | 0.46315131 |
| 73 | PIK3CA | 0.44266474 |
| 74 | PLK3 | 0.42378502 |
| 75 | GRK5 | 0.42344645 |
| 76 | NTRK2 | 0.41061409 |
| 77 | FES | 0.40624472 |
| 78 | TAF1 | 0.39876022 |
| 79 | MAPKAPK5 | 0.36169171 |
| 80 | NME1 | 0.35461749 |
| 81 | MAP3K4 | 0.34941049 |
| 82 | SYK | 0.34654867 |
| 83 | SCYL2 | 0.34408447 |
| 84 | PRKCG | 0.33065200 |
| 85 | CSNK2A1 | 0.31486941 |
| 86 | IGF1R | 0.31004255 |
| 87 | PDK2 | 0.29724655 |
| 88 | CAMK2A | 0.29643685 |
| 89 | MOS | 0.28816585 |
| 90 | RPS6KA5 | 0.27546406 |
| 91 | PRKCA | 0.27475330 |
| 92 | PRKACA | 0.26470822 |
| 93 | PRKD3 | 0.25823813 |
| 94 | LCK | 0.25736002 |
| 95 | FLT3 | 0.25600261 |
| 96 | MATK | 0.25432231 |
| 97 | ADRBK1 | 0.25253700 |
| 98 | CDK8 | 0.25066444 |
| 99 | GRK7 | 0.24991585 |
| 100 | CSNK2A2 | 0.24655121 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.26062639 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.33007003 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.15200546 |
| 4 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.99745914 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.90687135 |
| 6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.62254982 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.54040263 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.51713595 |
| 9 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.21523480 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.01825654 |
| 11 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.96079123 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 1.89018126 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.86515836 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.83123448 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.67447807 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.66013761 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.64339955 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.61423753 |
| 19 | Ribosome_Homo sapiens_hsa03010 | 1.57909599 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.56543899 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.49496238 |
| 22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.47512801 |
| 23 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.42521034 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.34828568 |
| 25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.32083942 |
| 26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.29983962 |
| 27 | Peroxisome_Homo sapiens_hsa04146 | 1.25971025 |
| 28 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.22647370 |
| 29 | Taste transduction_Homo sapiens_hsa04742 | 1.21608635 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.18216805 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.13238150 |
| 32 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.06440657 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.06147294 |
| 34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.05238273 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.04492677 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.04012330 |
| 37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.03277084 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.02096278 |
| 39 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.00123706 |
| 40 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.99433873 |
| 41 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.99015734 |
| 42 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.97295135 |
| 43 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.95356072 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.92947223 |
| 45 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.88630252 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.85847001 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.85609969 |
| 48 | Homologous recombination_Homo sapiens_hsa03440 | 0.85516970 |
| 49 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.84371965 |
| 50 | Spliceosome_Homo sapiens_hsa03040 | 0.82114528 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.80670884 |
| 52 | Basal transcription factors_Homo sapiens_hsa03022 | 0.78683974 |
| 53 | Nicotine addiction_Homo sapiens_hsa05033 | 0.78589626 |
| 54 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.75500046 |
| 55 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.73960125 |
| 56 | Viral myocarditis_Homo sapiens_hsa05416 | 0.68923155 |
| 57 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.67859368 |
| 58 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.66064038 |
| 59 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.65685648 |
| 60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.65337654 |
| 61 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.63086363 |
| 62 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.61948384 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.60978345 |
| 64 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.60874115 |
| 65 | GABAergic synapse_Homo sapiens_hsa04727 | 0.60710716 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.60064465 |
| 67 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.58476968 |
| 68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58417647 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.58228298 |
| 70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.57736562 |
| 71 | Salmonella infection_Homo sapiens_hsa05132 | 0.57563528 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57173341 |
| 73 | Olfactory transduction_Homo sapiens_hsa04740 | 0.55501393 |
| 74 | Morphine addiction_Homo sapiens_hsa05032 | 0.52926284 |
| 75 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.52465902 |
| 76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52277284 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.50638300 |
| 78 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50560929 |
| 79 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.48679432 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48132470 |
| 81 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.47468743 |
| 82 | Mismatch repair_Homo sapiens_hsa03430 | 0.46725981 |
| 83 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.46077573 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44830340 |
| 85 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.44408294 |
| 86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.44224046 |
| 87 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.43927417 |
| 88 | Carbon metabolism_Homo sapiens_hsa01200 | 0.42731389 |
| 89 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.42612953 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.42155579 |
| 91 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42057512 |
| 92 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.40886648 |
| 93 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.39435064 |
| 94 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.37002902 |
| 95 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.36980729 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.36785143 |
| 97 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.36355902 |
| 98 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.32556839 |
| 99 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.32302972 |
| 100 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.31325686 |

