GAPDHP69

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of mitotic metaphase/anaphase transition (GO:0045842)9.22606282
2positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)9.22606282
3positive regulation of mitotic sister chromatid separation (GO:1901970)9.22606282
4ribosomal small subunit assembly (GO:0000028)8.76694759
5negative regulation of Ras GTPase activity (GO:0034261)8.54473347
6eosinophil chemotaxis (GO:0048245)7.96223087
7negative regulation of T cell receptor signaling pathway (GO:0050860)7.94820815
8eosinophil migration (GO:0072677)7.19299735
9regulation of sister chromatid cohesion (GO:0007063)7.05365178
10fucose catabolic process (GO:0019317)6.96980649
11L-fucose metabolic process (GO:0042354)6.96980649
12L-fucose catabolic process (GO:0042355)6.96980649
13regulation of mononuclear cell migration (GO:0071675)6.54614861
14negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)6.20720138
15positive regulation of chromosome segregation (GO:0051984)6.19323255
16branch elongation of an epithelium (GO:0060602)6.14789991
17negative regulation of peptidyl-threonine phosphorylation (GO:0010801)6.12097920
18negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)5.67952805
19coenzyme A biosynthetic process (GO:0015937)5.60548371
20proteasome assembly (GO:0043248)5.59461024
21vesicle fusion (GO:0006906)5.50492004
22autophagic vacuole fusion (GO:0000046)4.91489833
23regulation of T cell receptor signaling pathway (GO:0050856)4.89535971
24macrophage chemotaxis (GO:0048246)4.71268936
25double-strand break repair via nonhomologous end joining (GO:0006303)4.66500904
26non-recombinational repair (GO:0000726)4.66500904
27peptidyl-lysine dimethylation (GO:0018027)4.42304102
28localization within membrane (GO:0051668)4.31241869
29organ growth (GO:0035265)4.25918192
30protein import into peroxisome matrix (GO:0016558)4.24360394
31positive regulation of calcium ion import (GO:0090280)4.15411716
32establishment of mitotic spindle orientation (GO:0000132)4.15361911
33axis elongation (GO:0003401)4.12552643
34monocyte chemotaxis (GO:0002548)4.11004270
35seminiferous tubule development (GO:0072520)3.96916299
36preassembly of GPI anchor in ER membrane (GO:0016254)3.95626931
37pantothenate metabolic process (GO:0015939)3.89288318
38iron-sulfur cluster assembly (GO:0016226)3.84149670
39metallo-sulfur cluster assembly (GO:0031163)3.84149670
40fucose metabolic process (GO:0006004)3.83262665
41regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.80812975
42ribonucleoside bisphosphate biosynthetic process (GO:0034030)3.76841180
43nucleoside bisphosphate biosynthetic process (GO:0033866)3.76841180
44purine nucleoside bisphosphate biosynthetic process (GO:0034033)3.76841180
45establishment of mitotic spindle localization (GO:0040001)3.76637951
46organelle membrane fusion (GO:0090174)3.73816265
47detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)3.73000756
48regulation of autophagic vacuole assembly (GO:2000785)3.71679221
49oxidative demethylation (GO:0070989)3.68365910
50fucosylation (GO:0036065)3.65542784
51negative regulation of GTP catabolic process (GO:0033125)3.64184514
52negative regulation of GTPase activity (GO:0034260)3.64184514
53energy coupled proton transport, down electrochemical gradient (GO:0015985)3.59233533
54ATP synthesis coupled proton transport (GO:0015986)3.59233533
55coenzyme A metabolic process (GO:0015936)3.57656222
56regulation of beta-amyloid formation (GO:1902003)3.52438058
57intracellular protein transmembrane import (GO:0044743)3.47316136
58transcription elongation from RNA polymerase III promoter (GO:0006385)3.46469552
59termination of RNA polymerase III transcription (GO:0006386)3.46469552
60mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.42735848
61regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.41791752
62establishment of spindle orientation (GO:0051294)3.38615950
63organelle fusion (GO:0048284)3.38321855
64regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.32832959
65negative regulation of macroautophagy (GO:0016242)3.31524478
66telomere maintenance via recombination (GO:0000722)3.28196952
67acrosome assembly (GO:0001675)3.26868691
68DNA deamination (GO:0045006)3.25820446
69negative regulation of circadian rhythm (GO:0042754)3.25074916
70folic acid-containing compound biosynthetic process (GO:0009396)3.15605784
71detection of chemical stimulus involved in sensory perception of taste (GO:0050912)3.13779544
72positive chemotaxis (GO:0050918)3.09314265
73membrane budding (GO:0006900)3.05602613
74RNA methylation (GO:0001510)3.05211067
75establishment of protein localization to mitochondrial membrane (GO:0090151)3.04945355
76GTP biosynthetic process (GO:0006183)3.03398872
77mitochondrial RNA metabolic process (GO:0000959)3.00727610
78regulation of fibroblast growth factor receptor signaling pathway (GO:0040036)3.00165053
79regulation of vacuole organization (GO:0044088)2.97790289
80imidazole-containing compound metabolic process (GO:0052803)2.97186679
81RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.93866265
82tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.93866265
83regulation of cellular amino acid metabolic process (GO:0006521)2.92433979
84GPI anchor biosynthetic process (GO:0006506)2.91601755
85tRNA modification (GO:0006400)2.91555969
86protein neddylation (GO:0045116)2.91297988
87ER to Golgi vesicle-mediated transport (GO:0006888)2.90235060
88DNA demethylation (GO:0080111)2.88530849
89histone H3-K9 methylation (GO:0051567)2.86526171
90establishment of protein localization to peroxisome (GO:0072663)2.85308205
91protein localization to peroxisome (GO:0072662)2.85308205
92protein targeting to peroxisome (GO:0006625)2.85308205
93mitotic recombination (GO:0006312)2.82030036
94DNA integration (GO:0015074)2.81081979
95GPI anchor metabolic process (GO:0006505)2.81012378
967-methylguanosine mRNA capping (GO:0006370)2.77743027
97single-organism membrane fusion (GO:0044801)2.77416617
98negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.76924149
99prenylation (GO:0097354)11.1662514
100protein prenylation (GO:0018342)11.1662514

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse8.41531328
2GATA1_22025678_ChIP-Seq_K562_Human5.70467738
3VDR_22108803_ChIP-Seq_LS180_Human5.07049799
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.44572678
5GABP_17652178_ChIP-ChIP_JURKAT_Human4.05071625
6NOTCH1_21737748_ChIP-Seq_TLL_Human3.49660806
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.96086045
8FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.95060636
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.91575887
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.83464622
11YY1_21170310_ChIP-Seq_MESCs_Mouse2.82751987
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.71543058
13CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.70922803
14SRF_21415370_ChIP-Seq_HL-1_Mouse2.57494540
15RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.54261583
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.52217081
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.45317481
18MYC_18555785_ChIP-Seq_MESCs_Mouse2.34770935
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.31559597
20AR_21572438_ChIP-Seq_LNCaP_Human2.25691238
21ZNF274_21170338_ChIP-Seq_K562_Hela2.07237848
22VDR_23849224_ChIP-Seq_CD4+_Human1.99484598
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.94544636
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.93932020
25PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.80306943
26SRY_22984422_ChIP-ChIP_TESTIS_Rat1.79422752
27IRF1_19129219_ChIP-ChIP_H3396_Human1.78961693
28SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.73164546
29CREB1_15753290_ChIP-ChIP_HEK293T_Human1.68768713
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.67835539
31MYC_18358816_ChIP-ChIP_MESCs_Mouse1.60250216
32ELK1_19687146_ChIP-ChIP_HELA_Human1.55810633
33NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.52437278
34POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.49100969
35FOXP3_21729870_ChIP-Seq_TREG_Human1.48306711
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.46006231
37HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.36490082
38ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.35626640
39E2F4_17652178_ChIP-ChIP_JURKAT_Human1.31315910
40PCGF2_27294783_Chip-Seq_NPCs_Mouse1.30795034
41ZNF263_19887448_ChIP-Seq_K562_Human1.30395633
42MYC_19030024_ChIP-ChIP_MESCs_Mouse1.27686279
43PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.26597978
44EGR1_23403033_ChIP-Seq_LIVER_Mouse1.26418766
45GABP_19822575_ChIP-Seq_HepG2_Human1.25586404
46TP53_22573176_ChIP-Seq_HFKS_Human1.25018118
47BCAT_22108803_ChIP-Seq_LS180_Human1.20179449
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16579644
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14034808
50E2F1_18555785_ChIP-Seq_MESCs_Mouse1.09972250
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.09939384
52KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.09195070
53TTF2_22483619_ChIP-Seq_HELA_Human1.05226974
54FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02824973
55FOXA1_25329375_ChIP-Seq_VCAP_Human1.02824973
56SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99570830
57DCP1A_22483619_ChIP-Seq_HELA_Human0.97932655
58HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.96990163
59POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96963006
60TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96963006
61CTBP1_25329375_ChIP-Seq_LNCAP_Human0.94506820
62FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.94251882
63P53_22127205_ChIP-Seq_FIBROBLAST_Human0.93894732
64NANOG_20526341_ChIP-Seq_ESCs_Human0.93477958
65NFE2_27457419_Chip-Seq_LIVER_Mouse0.92141978
66MYC_19079543_ChIP-ChIP_MESCs_Mouse0.91014979
67FOXH1_21741376_ChIP-Seq_EPCs_Human0.90853444
68TAF15_26573619_Chip-Seq_HEK293_Human0.89862173
69GATA3_26560356_Chip-Seq_TH1_Human0.87644338
70FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.86199409
71TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.85068291
72SOX2_19829295_ChIP-Seq_ESCs_Human0.83762896
73NANOG_19829295_ChIP-Seq_ESCs_Human0.83762896
74CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.83550908
75EZH2_22144423_ChIP-Seq_EOC_Human0.83265017
76ERG_20517297_ChIP-Seq_VCAP_Human0.83074118
77AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82542873
78MYC_18940864_ChIP-ChIP_HL60_Human0.82325467
79STAT3_1855785_ChIP-Seq_MESCs_Mouse0.82043281
80IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.81578838
81FUS_26573619_Chip-Seq_HEK293_Human0.80480768
82CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.80465324
83P300_19829295_ChIP-Seq_ESCs_Human0.80249294
84RXR_22108803_ChIP-Seq_LS180_Human0.79609446
85ZFP57_27257070_Chip-Seq_ESCs_Mouse0.79502101
86XRN2_22483619_ChIP-Seq_HELA_Human0.78355441
87EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.74331366
88POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.74251931
89TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.73629975
90FOXH1_21741376_ChIP-Seq_ESCs_Human0.73102121
91POU5F1_16153702_ChIP-ChIP_HESCs_Human0.72330675
92GATA3_21878914_ChIP-Seq_MCF-7_Human0.71063959
93GATA3_21867929_ChIP-Seq_TH1_Mouse0.70724077
94RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.70182355
95ELK1_22589737_ChIP-Seq_MCF10A_Human0.69667479
96NANOG_16153702_ChIP-ChIP_HESCs_Human0.68555204
97AR_20517297_ChIP-Seq_VCAP_Human0.67205776
98NR3C1_21868756_ChIP-Seq_MCF10A_Human0.65735602
99TCF4_22108803_ChIP-Seq_LS180_Human0.65542031
100EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.65380944

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation6.34767170
2MP0006082_CNS_inflammation4.18399476
3MP0001919_abnormal_reproductive_system3.02459302
4MP0001663_abnormal_digestive_system2.96554508
5MP0002163_abnormal_gland_morphology2.58602474
6MP0001664_abnormal_digestion2.57218482
7MP0000467_abnormal_esophagus_morphology2.54383781
8MP0005360_urolithiasis2.28228283
9MP0002876_abnormal_thyroid_physiology2.26132099
10MP0005381_digestive/alimentary_phenotyp2.20282626
11MP0002751_abnormal_autonomic_nervous2.19549750
12MP0005389_reproductive_system_phenotype2.06353258
13MP0000566_synostosis10.1678273
14MP0008058_abnormal_DNA_repair1.77176290
15MP0009379_abnormal_foot_pigmentation1.75676132
16MP0003115_abnormal_respiratory_system1.67645094
17MP0003937_abnormal_limbs/digits/tail_de1.60633377
18MP0002102_abnormal_ear_morphology1.58140616
19MP0006292_abnormal_olfactory_placode1.54029794
20MP0000383_abnormal_hair_follicle1.51558763
21MP0005084_abnormal_gallbladder_morpholo1.50523874
22MP0005379_endocrine/exocrine_gland_phen1.47685967
23MP0003195_calcinosis1.44555760
24MP0001293_anophthalmia1.42237418
25MP0008875_abnormal_xenobiotic_pharmacok1.32306250
26MP0008872_abnormal_physiological_respon1.32095764
27MP0003646_muscle_fatigue1.28217149
28MP0005671_abnormal_response_to1.28105478
29MP0001348_abnormal_lacrimal_gland1.26215736
30MP0005166_decreased_susceptibility_to1.24370162
31MP0001764_abnormal_homeostasis1.19814546
32MP0000490_abnormal_crypts_of1.19739646
33MP0002736_abnormal_nociception_after1.14723486
34MP0004142_abnormal_muscle_tone1.14626792
35MP0000534_abnormal_ureter_morphology1.11994890
36MP0001286_abnormal_eye_development1.10685071
37MP0000372_irregular_coat_pigmentation1.09538560
38MP0006072_abnormal_retinal_apoptosis1.08411371
39MP0004145_abnormal_muscle_electrophysio1.05711748
40MP0002277_abnormal_respiratory_mucosa1.04954761
41MP0005645_abnormal_hypothalamus_physiol1.02086857
42MP0010678_abnormal_skin_adnexa0.99995101
43MP0001915_intracranial_hemorrhage0.99078291
44MP0003763_abnormal_thymus_physiology0.92810766
45MP0000026_abnormal_inner_ear0.92093159
46MP0001529_abnormal_vocalization0.91996672
47MP0008877_abnormal_DNA_methylation0.91206546
48MP0001968_abnormal_touch/_nociception0.89753760
49MP0001963_abnormal_hearing_physiology0.89648063
50MP0005551_abnormal_eye_electrophysiolog0.88744318
51MP0003878_abnormal_ear_physiology0.88203577
52MP0005377_hearing/vestibular/ear_phenot0.88203577
53MP0002210_abnormal_sex_determination0.87608528
54MP0001485_abnormal_pinna_reflex0.87573591
55MP0005253_abnormal_eye_physiology0.86117124
56MP0000358_abnormal_cell_content/0.85020678
57MP0004742_abnormal_vestibular_system0.83639930
58MP0005397_hematopoietic_system_phenotyp0.83624952
59MP0001545_abnormal_hematopoietic_system0.83624952
60MP0002019_abnormal_tumor_incidence0.83017711
61MP0004885_abnormal_endolymph0.81811538
62MP0006276_abnormal_autonomic_nervous0.81802649
63MP0003122_maternal_imprinting0.81762392
64MP0002837_dystrophic_cardiac_calcinosis0.78909649
65MP0000428_abnormal_craniofacial_morphol0.78413119
66MP0001873_stomach_inflammation0.77542812
67MP0010155_abnormal_intestine_physiology0.76097039
68MP0002184_abnormal_innervation0.75300564
69MP0000470_abnormal_stomach_morphology0.74772502
70MP0002109_abnormal_limb_morphology0.73333015
71MP0000685_abnormal_immune_system0.73020423
72MP0005501_abnormal_skin_physiology0.68768544
73MP0002234_abnormal_pharynx_morphology0.68655142
74MP0001501_abnormal_sleep_pattern0.67689755
75MP0005085_abnormal_gallbladder_physiolo0.67276104
76MP0003283_abnormal_digestive_organ0.67023503
77MP0003252_abnormal_bile_duct0.66935946
78MP0003942_abnormal_urinary_system0.66313019
79MP0005332_abnormal_amino_acid0.65267066
80MP0002938_white_spotting0.65062472
81MP0003136_yellow_coat_color0.63194941
82MP0003186_abnormal_redox_activity0.62733102
83MP0003936_abnormal_reproductive_system0.61347471
84MP0004147_increased_porphyrin_level0.60554975
85MP0000477_abnormal_intestine_morphology0.59407348
86MP0001984_abnormal_olfaction0.57013334
87MP0003718_maternal_effect0.56595864
88MP0002752_abnormal_somatic_nervous0.55645464
89MP0002405_respiratory_system_inflammati0.55511242
90MP0001835_abnormal_antigen_presentation0.55410640
91MP0000049_abnormal_middle_ear0.54666558
92MP0005197_abnormal_uvea_morphology0.53857770
93MP0001986_abnormal_taste_sensitivity0.53522686
94MP0003453_abnormal_keratinocyte_physiol0.53463783
95MP0001119_abnormal_female_reproductive0.53379522
96MP0001800_abnormal_humoral_immune0.52859315
97MP0005195_abnormal_posterior_eye0.52719422
98MP0003121_genomic_imprinting0.52258987
99MP0003329_amyloid_beta_deposits0.52152728
100MP0003011_delayed_dark_adaptation0.51344626

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of long-chain fatty-acid metabolism (HP:0010964)7.79482478
2Duplicated collecting system (HP:0000081)7.05738561
3Abnormality of the renal collecting system (HP:0004742)6.43859759
4Large for gestational age (HP:0001520)5.81198817
5Long foot (HP:0001833)5.54305013
6Abnormality of fatty-acid metabolism (HP:0004359)4.71134177
7Adactyly (HP:0009776)4.47359156
8Progressive muscle weakness (HP:0003323)4.21642465
9Acute necrotizing encephalopathy (HP:0006965)4.09292836
10Acute lymphatic leukemia (HP:0006721)3.98869979
11Severe muscular hypotonia (HP:0006829)3.91461039
12Hypoplastic pelvis (HP:0008839)3.87710411
13Ureteral duplication (HP:0000073)3.77590492
14Dry hair (HP:0011359)3.71308842
15Brushfield spots (HP:0001088)3.61133071
16Pulmonary artery stenosis (HP:0004415)3.59932601
17Abnormal mitochondria in muscle tissue (HP:0008316)3.58710231
18Acute encephalopathy (HP:0006846)3.57288594
19Ureteral stenosis (HP:0000071)3.55315576
20Steatorrhea (HP:0002570)3.55056832
21Mitochondrial inheritance (HP:0001427)3.52328524
22Progressive macrocephaly (HP:0004481)3.33386261
23Broad-based gait (HP:0002136)3.30745481
24Increased CSF lactate (HP:0002490)3.25813433
25Menstrual irregularities (HP:0000858)3.22397990
26Lactic acidosis (HP:0003128)3.20283752
27Autoamputation (HP:0001218)3.19167330
28Ureteral obstruction (HP:0006000)3.15758691
29Increased hepatocellular lipid droplets (HP:0006565)3.10142220
30Reduced subcutaneous adipose tissue (HP:0003758)2.95288299
31Hepatocellular necrosis (HP:0001404)2.94592805
32Lipid accumulation in hepatocytes (HP:0006561)2.89036754
33Hepatic necrosis (HP:0002605)2.87521901
34Increased serum lactate (HP:0002151)2.75456849
35Fat malabsorption (HP:0002630)2.74087015
36Hypoplastic nipples (HP:0002557)2.70340672
37Decreased muscle mass (HP:0003199)2.64121750
38Clubbing of toes (HP:0100760)2.62670889
39Cerebral edema (HP:0002181)2.48237556
40Exercise intolerance (HP:0003546)2.47611771
41Respiratory failure (HP:0002878)2.45515063
42Renal Fanconi syndrome (HP:0001994)2.43271867
43Congenital stationary night blindness (HP:0007642)2.39239926
44Transposition of the great arteries (HP:0001669)2.37232622
45Abnormal connection of the cardiac segments (HP:0011545)2.37232622
46Abnormal ventriculo-arterial connection (HP:0011563)2.37232622
47Sudden death (HP:0001699)2.34487377
48Polymicrogyria (HP:0002126)2.33895219
49Decreased lacrimation (HP:0000633)2.29180152
50Epiphyseal stippling (HP:0010655)2.27275526
51Wide intermamillary distance (HP:0006610)2.26887372
52CNS demyelination (HP:0007305)2.26013026
53Optic disc pallor (HP:0000543)2.24997551
54Anhidrosis (HP:0000970)2.24732457
55Increased number of teeth (HP:0011069)2.22774530
56Rhabdomyolysis (HP:0003201)2.21645956
57Abnormal auditory evoked potentials (HP:0006958)2.21477854
58Absent rod-and cone-mediated responses on ERG (HP:0007688)2.16667944
59Palmoplantar hyperkeratosis (HP:0000972)2.15315961
60Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.10718009
61Myoglobinuria (HP:0002913)2.08827471
62Anxiety (HP:0000739)2.08368374
63Chorioretinal coloboma (HP:0000567)2.06912861
64Pendular nystagmus (HP:0012043)2.05711457
653-Methylglutaconic aciduria (HP:0003535)2.02961301
66Palmar hyperkeratosis (HP:0010765)1.98621460
67Increased serum pyruvate (HP:0003542)1.95922025
68Polyneuropathy (HP:0001271)1.94958169
69Exertional dyspnea (HP:0002875)1.94874429
70Abnormality of the labia minora (HP:0012880)1.94666457
71Female pseudohermaphroditism (HP:0010458)1.90505873
72Abnormal rod and cone electroretinograms (HP:0008323)1.90108382
73Decreased central vision (HP:0007663)1.88029070
74Reticulocytopenia (HP:0001896)1.84640943
75Cerebral hypomyelination (HP:0006808)1.84268631
76Severe combined immunodeficiency (HP:0004430)1.83550350
77Abnormality of urine glucose concentration (HP:0011016)1.82959116
78Glycosuria (HP:0003076)1.82959116
79Abnormal epiphyseal ossification (HP:0010656)1.82792199
80Hypoplastic iliac wings (HP:0002866)1.82112324
81Leukodystrophy (HP:0002415)1.77526073
82Depressed nasal ridge (HP:0000457)1.77052789
83Hypoproteinemia (HP:0003075)1.76170852
84Overfolded helix (HP:0000396)1.75011813
85Increased intramyocellular lipid droplets (HP:0012240)1.74068144
86Abnormality of vision evoked potentials (HP:0000649)1.73640068
87Abnormality of cells of the erythroid lineage (HP:0012130)1.69084829
88Abnormality of glycolysis (HP:0004366)1.68204232
89Plantar hyperkeratosis (HP:0007556)1.67677575
90Lethargy (HP:0001254)1.67621315
91Pancreatic cysts (HP:0001737)1.67221583
92Pancreatic fibrosis (HP:0100732)1.65667407
93Spastic tetraplegia (HP:0002510)1.64792609
94Hyperglycinemia (HP:0002154)1.64097367
95B lymphocytopenia (HP:0010976)1.62224956
96Abnormal number of erythroid precursors (HP:0012131)1.61827986
97True hermaphroditism (HP:0010459)1.61608374
98Thyroiditis (HP:0100646)1.60414164
99Large hands (HP:0001176)1.60183558
100IgG deficiency (HP:0004315)1.59033115

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MKNK16.37399231
2TAOK24.69561049
3TAOK14.60050093
4MAP3K113.73990857
5MAP3K33.23524244
6MAP2K32.90332376
7MKNK210.9122371
8JAK31.95289814
9ABL21.88846853
10VRK21.67186329
11TLK11.63992545
12DYRK1A1.61355172
13ZAK1.49190502
14BUB11.33385038
15SRPK11.25341223
16VRK11.18415112
17WNK40.97546554
18MAP3K50.94768778
19CHEK20.87401392
20TIE10.81276300
21WNK30.79005681
22GRK10.78766197
23TXK0.78520993
24MAP4K20.76866319
25NUAK10.74801205
26TAF10.72087073
27ADRBK20.69300437
28TSSK60.66228106
29PRKCQ0.64834759
30MAP3K80.55726016
31FRK0.55701605
32NEK10.53250470
33BCKDK0.53137168
34PDK20.52898078
35TRIM280.50570650
36EIF2AK30.50043754
37MAP3K10.47209111
38NME20.47029620
39PLK30.45965416
40KDR0.45964484
41MAP3K120.44579306
42STK160.44142934
43AURKA0.44090731
44DYRK20.40152344
45BMPR1B0.39931906
46STK390.37775369
47DAPK30.36659895
48NME10.36323382
49PBK0.32851870
50CSNK1A10.32089453
51PLK40.31498755
52OXSR10.30600407
53MST40.29978847
54INSRR0.29758538
55CDC70.27833987
56CSNK2A20.27514081
57MYLK0.26646388
58CSNK2A10.23106239
59GRK50.22119179
60OBSCN0.22099286
61PASK0.21952960
62PHKG20.21640766
63PHKG10.21640766
64MAPK150.20460398
65LMTK20.19706763
66DAPK10.19320181
67RPS6KA50.19120365
68SMG10.19043733
69MAP4K10.18067384
70PRKCG0.17755715
71EIF2AK10.17385673
72CCNB10.15930719
73IGF1R0.15855281
74EIF2AK20.15499872
75AURKB0.15476435
76PLK20.15390727
77PRKCD0.14461697
78PRKCA0.14323125
79CSNK1E0.13959582
80PRKACA0.12871982
81CSNK1G30.12850243
82STK40.12731914
83TGFBR10.12249293
84LIMK10.11945826
85ABL10.11360829
86EPHB20.10795878
87WEE10.10626260
88EPHA20.10524121
89GRK70.10464659
90CDK80.09224900
91PLK10.08195172
92CSNK1G20.08012929
93ADRBK10.07117356
94ITK0.06849200
95MUSK0.06725365
96CDK90.06618699
97CSNK1G10.06340588
98PINK10.05762612
99CASK0.04416445
100PRKCB0.04360632

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.32736863
2SNARE interactions in vesicular transport_Homo sapiens_hsa041304.21169274
3Pantothenate and CoA biosynthesis_Homo sapiens_hsa007703.60849364
4RNA polymerase_Homo sapiens_hsa030203.38908459
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.99801013
6Oxidative phosphorylation_Homo sapiens_hsa001902.82878074
7Ribosome_Homo sapiens_hsa030102.67623876
8Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.33325331
9One carbon pool by folate_Homo sapiens_hsa006702.29300652
10Parkinsons disease_Homo sapiens_hsa050122.26982913
11Fatty acid elongation_Homo sapiens_hsa000622.04736747
12Propanoate metabolism_Homo sapiens_hsa006401.91447662
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.86639844
14Huntingtons disease_Homo sapiens_hsa050161.85342724
15Butanoate metabolism_Homo sapiens_hsa006501.80815148
16Protein export_Homo sapiens_hsa030601.72291964
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.66692922
18Tryptophan metabolism_Homo sapiens_hsa003801.66545839
19Alzheimers disease_Homo sapiens_hsa050101.53237729
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.49720567
21Systemic lupus erythematosus_Homo sapiens_hsa053221.48621134
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.41172651
23Pyrimidine metabolism_Homo sapiens_hsa002401.38456051
24Taste transduction_Homo sapiens_hsa047421.34426765
25Nucleotide excision repair_Homo sapiens_hsa034201.33859924
26Peroxisome_Homo sapiens_hsa041461.28500855
27Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.26864606
28Nitrogen metabolism_Homo sapiens_hsa009101.25890194
29beta-Alanine metabolism_Homo sapiens_hsa004101.25679126
30Cardiac muscle contraction_Homo sapiens_hsa042601.25673026
31Mismatch repair_Homo sapiens_hsa034301.18216814
32Asthma_Homo sapiens_hsa053101.16999790
33Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.15855902
34Primary immunodeficiency_Homo sapiens_hsa053401.15344884
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.14213235
36Glycerolipid metabolism_Homo sapiens_hsa005611.05242847
37Fatty acid degradation_Homo sapiens_hsa000711.02830221
38Sulfur relay system_Homo sapiens_hsa041221.01588628
39DNA replication_Homo sapiens_hsa030300.99893707
40Vitamin B6 metabolism_Homo sapiens_hsa007500.99730803
41Caffeine metabolism_Homo sapiens_hsa002320.98947286
42RNA transport_Homo sapiens_hsa030130.96336441
43Non-homologous end-joining_Homo sapiens_hsa034500.95006238
44Intestinal immune network for IgA production_Homo sapiens_hsa046720.94612324
45Purine metabolism_Homo sapiens_hsa002300.92153026
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91955224
47Maturity onset diabetes of the young_Homo sapiens_hsa049500.90367818
48Basal transcription factors_Homo sapiens_hsa030220.88665200
49RNA degradation_Homo sapiens_hsa030180.87731411
50Homologous recombination_Homo sapiens_hsa034400.87271777
51Allograft rejection_Homo sapiens_hsa053300.86834759
52Autoimmune thyroid disease_Homo sapiens_hsa053200.84428966
53Lysine degradation_Homo sapiens_hsa003100.83274480
54Phototransduction_Homo sapiens_hsa047440.81435641
55Fat digestion and absorption_Homo sapiens_hsa049750.79532039
56Fatty acid metabolism_Homo sapiens_hsa012120.78266055
57Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78124388
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77137677
59Linoleic acid metabolism_Homo sapiens_hsa005910.70409566
60Sulfur metabolism_Homo sapiens_hsa009200.69951453
61Metabolic pathways_Homo sapiens_hsa011000.67536059
62Steroid biosynthesis_Homo sapiens_hsa001000.66566237
63Type I diabetes mellitus_Homo sapiens_hsa049400.65324702
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65110221
65Fanconi anemia pathway_Homo sapiens_hsa034600.62996624
66Chemical carcinogenesis_Homo sapiens_hsa052040.61710743
67Primary bile acid biosynthesis_Homo sapiens_hsa001200.60447597
68Alcoholism_Homo sapiens_hsa050340.58514001
69Carbon metabolism_Homo sapiens_hsa012000.58223090
70Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57870344
71Retinol metabolism_Homo sapiens_hsa008300.56700009
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.55342411
73Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53925049
74Graft-versus-host disease_Homo sapiens_hsa053320.53067327
75Cysteine and methionine metabolism_Homo sapiens_hsa002700.50385706
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.49647839
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48394870
78Folate biosynthesis_Homo sapiens_hsa007900.47847446
79Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44263945
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42525128
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.42095091
82Viral myocarditis_Homo sapiens_hsa054160.40013299
83Rheumatoid arthritis_Homo sapiens_hsa053230.39918554
84Epstein-Barr virus infection_Homo sapiens_hsa051690.38674080
85Arginine biosynthesis_Homo sapiens_hsa002200.37533275
86Pyruvate metabolism_Homo sapiens_hsa006200.37327438
87Steroid hormone biosynthesis_Homo sapiens_hsa001400.37157971
88Tyrosine metabolism_Homo sapiens_hsa003500.35624345
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.35138926
90Mineral absorption_Homo sapiens_hsa049780.33797083
91Hematopoietic cell lineage_Homo sapiens_hsa046400.33774274
92Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32781569
93Glutathione metabolism_Homo sapiens_hsa004800.32471227
94Olfactory transduction_Homo sapiens_hsa047400.32359366
95Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.30933855
96Spliceosome_Homo sapiens_hsa030400.29601337
97Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.28176185
98Base excision repair_Homo sapiens_hsa034100.27261430
99Biosynthesis of amino acids_Homo sapiens_hsa012300.25973034
100Nicotine addiction_Homo sapiens_hsa050330.25692422

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »