GAPVD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1monoubiquitinated protein deubiquitination (GO:0035520)5.65790509
2iron ion import (GO:0097286)4.82513308
3mitotic sister chromatid cohesion (GO:0007064)4.80055462
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.65973721
5negative regulation of cell killing (GO:0031342)4.65973721
6protoporphyrinogen IX metabolic process (GO:0046501)4.48964701
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.07184384
8nuclear pore complex assembly (GO:0051292)3.97200504
9positive regulation of gamma-delta T cell activation (GO:0046645)3.87534084
10regulation of DNA endoreduplication (GO:0032875)3.83497038
11definitive hemopoiesis (GO:0060216)3.74556026
12phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.74459343
13histone H3-K4 trimethylation (GO:0080182)3.59005730
14early endosome to late endosome transport (GO:0045022)3.55250447
15negative regulation of DNA repair (GO:0045738)3.52296924
16Golgi to endosome transport (GO:0006895)3.39639365
17peptidyl-lysine trimethylation (GO:0018023)3.34064423
18antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.33322315
19mitotic nuclear envelope disassembly (GO:0007077)3.29237560
20protoporphyrinogen IX biosynthetic process (GO:0006782)3.26418873
21nuclear pore organization (GO:0006999)3.26128473
22sister chromatid cohesion (GO:0007062)3.23696398
23regulation of protein polyubiquitination (GO:1902914)3.23328222
24nuclear envelope disassembly (GO:0051081)3.21010251
25membrane disassembly (GO:0030397)3.21010251
26meiotic chromosome segregation (GO:0045132)3.14847433
27embryonic hemopoiesis (GO:0035162)3.04964316
28negative regulation of TOR signaling (GO:0032007)3.03389088
29protein K48-linked deubiquitination (GO:0071108)3.03339676
30regulation of histone H3-K27 methylation (GO:0061085)3.03062512
31microtubule anchoring (GO:0034453)3.01051095
32rRNA catabolic process (GO:0016075)3.00654375
33negative T cell selection (GO:0043383)3.00132652
34DNA topological change (GO:0006265)2.98362671
35protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.96650376
36negative thymic T cell selection (GO:0045060)2.96252482
37regulation of establishment of cell polarity (GO:2000114)2.93854969
38regulation of centrosome cycle (GO:0046605)2.93394536
39protein K11-linked deubiquitination (GO:0035871)2.92935268
40regulation of centrosome duplication (GO:0010824)2.90543184
41keratinocyte development (GO:0003334)2.90392162
42negative regulation of execution phase of apoptosis (GO:1900118)2.90253269
43prenylation (GO:0097354)2.88009510
44protein prenylation (GO:0018342)2.88009510
45intra-S DNA damage checkpoint (GO:0031573)2.87884394
46positive regulation of RNA splicing (GO:0033120)2.87767617
47pore complex assembly (GO:0046931)2.87243504
48histone H3-K9 methylation (GO:0051567)2.85599375
49positive regulation of histone deacetylation (GO:0031065)2.84400497
50cytoplasmic mRNA processing body assembly (GO:0033962)2.83396902
51mitotic sister chromatid segregation (GO:0000070)2.81548049
52mitotic chromosome condensation (GO:0007076)2.80742862
53snRNA transcription (GO:0009301)2.79604210
54histone-serine phosphorylation (GO:0035404)2.79019288
55protein localization to microtubule cytoskeleton (GO:0072698)2.78476247
56erythrocyte development (GO:0048821)2.76371979
57regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.74733318
58protein export from nucleus (GO:0006611)2.74267465
59regulation of RNA export from nucleus (GO:0046831)2.74012263
60cellular response to ethanol (GO:0071361)2.72343088
61positive regulation of protein import into nucleus, translocation (GO:0033160)2.72095268
62UDP-N-acetylglucosamine metabolic process (GO:0006047)2.71417766
63nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.71053643
64DNA unwinding involved in DNA replication (GO:0006268)2.69060399
65macroautophagy (GO:0016236)2.68530977
66desmosome organization (GO:0002934)2.67557750
67corticosteroid receptor signaling pathway (GO:0031958)2.67472249
68DNA replication initiation (GO:0006270)2.66875932
69alternative mRNA splicing, via spliceosome (GO:0000380)2.66014316
70non-recombinational repair (GO:0000726)2.65339649
71double-strand break repair via nonhomologous end joining (GO:0006303)2.65339649
72regulation of gamma-delta T cell differentiation (GO:0045586)2.65309791
73regulation of sister chromatid cohesion (GO:0007063)2.65155420
74establishment of protein localization to Golgi (GO:0072600)2.65034868
75interkinetic nuclear migration (GO:0022027)2.64644680
76histone H3-K4 methylation (GO:0051568)2.64565117
77dosage compensation (GO:0007549)2.61240527
78negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.60637401
79negative regulation of histone methylation (GO:0031061)2.60060945
80glucocorticoid receptor signaling pathway (GO:0042921)2.59770416
81interleukin-6-mediated signaling pathway (GO:0070102)2.59563802
82COPII vesicle coating (GO:0048208)2.59479631
83neural tube formation (GO:0001841)2.57652947
84gene silencing by RNA (GO:0031047)2.57650613
85cilium or flagellum-dependent cell motility (GO:0001539)2.57552496
86TOR signaling (GO:0031929)2.56855561
87peptidyl-lysine methylation (GO:0018022)2.56819111
88histone lysine methylation (GO:0034968)2.56368002
89nuclear envelope organization (GO:0006998)2.55178248
90regulation of translational fidelity (GO:0006450)2.54813076
91mRNA splice site selection (GO:0006376)2.54386902
92regulation of gamma-delta T cell activation (GO:0046643)2.54321190
93regulation of nucleobase-containing compound transport (GO:0032239)2.54172890
94protein localization to cytoskeleton (GO:0044380)2.53091429
95histone phosphorylation (GO:0016572)2.51180747
96erythrocyte maturation (GO:0043249)2.50344479
97regulation of histone methylation (GO:0031060)2.50078754
98microtubule depolymerization (GO:0007019)2.49438236
99histone H3-K36 demethylation (GO:0070544)2.48788986
100negative regulation of cell cycle G2/M phase transition (GO:1902750)2.48730465
101protein localization to kinetochore (GO:0034501)2.48558739
102NLS-bearing protein import into nucleus (GO:0006607)2.47899484
103negative regulation of granulocyte differentiation (GO:0030853)2.46222339
104mRNA stabilization (GO:0048255)2.46139655
105RNA stabilization (GO:0043489)2.46139655
106growth hormone receptor signaling pathway (GO:0060396)2.45694396
107positive regulation of mRNA catabolic process (GO:0061014)2.45473391
108ether lipid metabolic process (GO:0046485)2.45114900
109positive regulation of erythrocyte differentiation (GO:0045648)2.44506153
110positive regulation of histone H3-K4 methylation (GO:0051571)2.43773739
111DNA conformation change (GO:0071103)2.42577374
112nucleus organization (GO:0006997)2.42556467
113activated T cell proliferation (GO:0050798)2.42407665
114porphyrin-containing compound biosynthetic process (GO:0006779)2.42117072
115regulation of interferon-beta biosynthetic process (GO:0045357)2.41253181
116histone mRNA catabolic process (GO:0071044)2.39924546
117peptidyl-lysine dimethylation (GO:0018027)2.39621863
118histone demethylation (GO:0016577)2.39450792
119histone H3-K9 modification (GO:0061647)2.37890898
120negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.37258771
121negative regulation of translation, ncRNA-mediated (GO:0040033)2.37258771
122regulation of translation, ncRNA-mediated (GO:0045974)2.37258771
123regulation of histone H3-K9 methylation (GO:0051570)2.35645129
124hepatocyte apoptotic process (GO:0097284)2.34344861
125regulation of erythrocyte differentiation (GO:0045646)2.33391759
126megakaryocyte development (GO:0035855)2.31434699
127leukocyte aggregation (GO:0070486)2.31371873
128negative regulation of T cell mediated immunity (GO:0002710)2.30639641
129modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.29445692
130modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.29445692
131positive regulation by organism of defense response of other organism involved in symbiotic interact2.29445692
132modulation by symbiont of host immune response (GO:0052553)2.29445692
133positive regulation by symbiont of host defense response (GO:0052509)2.29445692
134modulation by symbiont of host defense response (GO:0052031)2.29445692
135regulation of B cell receptor signaling pathway (GO:0050855)2.28102558
136regulation of mRNA catabolic process (GO:0061013)2.27965159
137B cell homeostasis (GO:0001782)2.27563840
138regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.25998610
139regulation of histone H3-K4 methylation (GO:0051569)2.23167072
140regulation of interleukin-12 biosynthetic process (GO:0045075)2.22223148
141T cell selection (GO:0045058)2.21347717
142positive regulation of mRNA metabolic process (GO:1903313)2.21201202
143sister chromatid segregation (GO:0000819)2.20799975
144lymphocyte homeostasis (GO:0002260)2.20600206
145positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.19275226
146positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.19275226
147positive regulation of mitotic sister chromatid separation (GO:1901970)2.19275226
148positive T cell selection (GO:0043368)2.19225171
149regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.19116203
150positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.19116203
151DNA geometric change (GO:0032392)2.18728977
152positive thymic T cell selection (GO:0045059)2.18704486
153regulation of centriole replication (GO:0046599)2.18045865
154DNA duplex unwinding (GO:0032508)2.18036620
155thymic T cell selection (GO:0045061)2.18024118
156heterotypic cell-cell adhesion (GO:0034113)2.17340159
157regulation of mRNA stability (GO:0043488)2.16443802
158positive regulation of B cell differentiation (GO:0045579)2.13849596
159microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.12649686
160nucleosome disassembly (GO:0006337)2.12042230
161protein-DNA complex disassembly (GO:0032986)2.12042230
162B cell receptor signaling pathway (GO:0050853)2.11406330
163peptidyl-threonine phosphorylation (GO:0018107)2.10357631
164protein localization to chromosome, centromeric region (GO:0071459)2.10061662
165positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.09959341
166T cell homeostasis (GO:0043029)2.09790767
167germ cell migration (GO:0008354)2.08289166
168pre-miRNA processing (GO:0031054)2.06911193
169positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.06807754

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.17049194
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.49936574
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.31704437
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.10644681
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.74004591
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.60511344
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.15274441
8SCL_19346495_ChIP-Seq_HPC-7_Human2.91289350
9STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.66507750
10E2F4_17652178_ChIP-ChIP_JURKAT_Human2.60433032
11STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.31959395
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.22831921
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.18423642
14RUNX_20019798_ChIP-Seq_JUKART_Human2.14705874
15* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.13410800
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.01850381
17VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.01436828
18PADI4_21655091_ChIP-ChIP_MCF-7_Human1.95522595
19* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.94622017
20FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.92484799
21PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.89412960
22FUS_26573619_Chip-Seq_HEK293_Human1.85963300
23ELK1_19687146_ChIP-ChIP_HELA_Human1.85012137
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.84815316
25NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.83885318
26* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.83408938
27MYC_22102868_ChIP-Seq_BL_Human1.81953788
28ESR1_20079471_ChIP-ChIP_T-47D_Human1.80852127
29IRF8_27001747_Chip-Seq_BMDM_Mouse1.79484413
30IRF8_21731497_ChIP-ChIP_J774_Mouse1.79362887
31GATA1_22025678_ChIP-Seq_K562_Human1.78272415
32* TCF7_22412390_ChIP-Seq_EML_Mouse1.72153995
33MYB_21317192_ChIP-Seq_ERMYB_Mouse1.64583732
34RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.62161565
35SMAD_19615063_ChIP-ChIP_OVARY_Human1.61217829
36TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.57928846
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.57416981
38TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.55819224
39* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.54896140
40YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54299750
41ER_23166858_ChIP-Seq_MCF-7_Human1.49400252
42TP53_16413492_ChIP-PET_HCT116_Human1.49272208
43BP1_19119308_ChIP-ChIP_Hs578T_Human1.48687113
44KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47973206
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.47961362
46Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.46173704
47MYB_26560356_Chip-Seq_TH2_Human1.45260001
48* GATA1_19941826_ChIP-Seq_K562_Human1.44061440
49FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.43289729
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.42104672
51VDR_22108803_ChIP-Seq_LS180_Human1.41672525
52FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.40830252
53MYB_26560356_Chip-Seq_TH1_Human1.39661413
54TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.38998040
55ZNF274_21170338_ChIP-Seq_K562_Hela1.38450952
56SPI1_23127762_ChIP-Seq_K562_Human1.38115496
57IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.37206466
58IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.37205798
59SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.36812048
60BRD4_27068464_Chip-Seq_AML-cells_Mouse1.32975711
61HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.32778856
62PKCTHETA_26484144_Chip-Seq_BREAST_Human1.32399649
63FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.30515007
64TFEB_21752829_ChIP-Seq_HELA_Human1.29934850
65SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.29789873
66ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.29144620
67VDR_24763502_ChIP-Seq_THP-1_Human1.28967346
68DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.27750423
69EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.27736729
70KDM2B_26808549_Chip-Seq_DND41_Human1.26752727
71FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.26309290
72RBPJ_22232070_ChIP-Seq_NCS_Mouse1.25547768
73VDR_21846776_ChIP-Seq_THP-1_Human1.25064143
74KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.22295232
75TAF15_26573619_Chip-Seq_HEK293_Human1.22128052
76PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.22057816
77UTX_26944678_Chip-Seq_JUKART_Human1.21661419
78MAF_26560356_Chip-Seq_TH1_Human1.19184526
79HOXB4_20404135_ChIP-ChIP_EML_Mouse1.19051492
80SALL4_18804426_ChIP-ChIP_XEN_Mouse1.18681546
81STAT4_19710469_ChIP-ChIP_TH1__Mouse1.18391591
82VDR_23849224_ChIP-Seq_CD4+_Human1.17780231
83* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.16748238
84TP63_19390658_ChIP-ChIP_HaCaT_Human1.16327682
85* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15840799
86VDR_24787735_ChIP-Seq_THP-1_Human1.15625806
87ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.15042669
88KDM5A_27292631_Chip-Seq_BREAST_Human1.14958607
89AR_21572438_ChIP-Seq_LNCaP_Human1.14618621
90KDM2B_26808549_Chip-Seq_JURKAT_Human1.14526939
91* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13578626
92* TCF4_23295773_ChIP-Seq_U87_Human1.11397623
93* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09717298
94TCF4_18268006_ChIP-ChIP_LS174T_Human1.09137221
95MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.08981592
96* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.07326304
97EZH2_27294783_Chip-Seq_NPCs_Mouse1.07056169
98CHD1_26751641_Chip-Seq_LNCaP_Human1.06734453
99PU_27001747_Chip-Seq_BMDM_Mouse1.06591312
100SMAD4_21799915_ChIP-Seq_A2780_Human1.06519184
101* GATA2_19941826_ChIP-Seq_K562_Human1.06494501
102RUNX1_22412390_ChIP-Seq_EML_Mouse1.05582810
103BRD4_25478319_ChIP-Seq_HGPS_Human1.05037835
104GATA1_19941827_ChIP-Seq_MEL_Mouse1.04374725
105RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.04040909
106NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.03120367
107FLI1_27457419_Chip-Seq_LIVER_Mouse1.03018672
108FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.00723300
109IGF1R_20145208_ChIP-Seq_DFB_Human0.98859719
110NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.97541643
111NRF2_20460467_ChIP-Seq_MEFs_Mouse0.97541643
112WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.96903545
113* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96887639
114KDM2B_26808549_Chip-Seq_SUP-B15_Human0.96430777
115OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95871242
116NOTCH1_21737748_ChIP-Seq_TLL_Human0.95843413
117MYCN_18555785_ChIP-Seq_MESCs_Mouse0.95835163
118ZFP57_27257070_Chip-Seq_ESCs_Mouse0.95782949
119FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.94170704
120CDX2_22108803_ChIP-Seq_LS180_Human0.93851785
121EWS_26573619_Chip-Seq_HEK293_Human0.92932005
122SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92812507
123SALL4_22934838_ChIP-ChIP_CD34+_Human0.92676168
124* PIAS1_25552417_ChIP-Seq_VCAP_Human0.92202440
125CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.91934820
126* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91868287
127CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91815159
128WT1_19549856_ChIP-ChIP_CCG9911_Human0.91762085
129CDX2_19796622_ChIP-Seq_MESCs_Mouse0.91201827
130AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91164806
131GATA3_27048872_Chip-Seq_THYMUS_Human0.91081956
132SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.90907747
133SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.90907747
134FOXO3_23340844_ChIP-Seq_DLD1_Human0.90816383
135GBX2_23144817_ChIP-Seq_PC3_Human0.90620057
136SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89892670
137AR_21909140_ChIP-Seq_LNCAP_Human0.89361221
138SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.89127549
139TP63_23658742_ChIP-Seq_EP156T_Human0.88111040
140* E2F1_18555785_Chip-Seq_ESCs_Mouse0.87415272
141POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87081904
142* ARNT_22903824_ChIP-Seq_MCF-7_Human0.85369628
143FOXA1_25552417_ChIP-Seq_VCAP_Human0.85315357
144* SPI1_23547873_ChIP-Seq_NB4_Human0.83340910
145KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.83329728
146CTNNB1_20460455_ChIP-Seq_HCT116_Human0.83193690
147SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.82773140
148DROSHA_22980978_ChIP-Seq_HELA_Human0.80910878
149GATA2_21666600_ChIP-Seq_HMVEC_Human0.79635900
150STAT3_23295773_ChIP-Seq_U87_Human0.78598761
151* AHR_22903824_ChIP-Seq_MCF-7_Human0.78545051
152PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.78056467
153KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.77862759

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation6.25874932
2MP0003787_abnormal_imprinting2.89202850
3MP0002166_altered_tumor_susceptibility2.44361430
4MP0010352_gastrointestinal_tract_polyps2.40616653
5MP0004808_abnormal_hematopoietic_stem2.36891481
6MP0009278_abnormal_bone_marrow2.33784773
7MP0003300_gastrointestinal_ulcer2.27403561
8MP0003786_premature_aging2.27098468
9MP0001661_extended_life_span2.24049660
10MP0008057_abnormal_DNA_replication2.23367340
11MP0002009_preneoplasia2.15896681
12MP0002396_abnormal_hematopoietic_system2.15074349
13MP0008995_early_reproductive_senescence2.11811567
14MP0005174_abnormal_tail_pigmentation2.11603915
15MP0002006_tumorigenesis2.05919012
16MP0008058_abnormal_DNA_repair2.03881142
17MP0003950_abnormal_plasma_membrane2.03744509
18MP0004233_abnormal_muscle_weight2.01945288
19MP0005076_abnormal_cell_differentiation1.98155202
20MP0003303_peritoneal_inflammation1.95945560
21MP0005451_abnormal_body_composition1.94761780
22MP0003111_abnormal_nucleus_morphology1.92968374
23MP0005397_hematopoietic_system_phenotyp1.92965983
24MP0001545_abnormal_hematopoietic_system1.92965983
25MP0000427_abnormal_hair_cycle1.87668817
26MP0005083_abnormal_biliary_tract1.86699820
27MP0003763_abnormal_thymus_physiology1.81562243
28MP0003656_abnormal_erythrocyte_physiolo1.81185452
29MP0004957_abnormal_blastocyst_morpholog1.80334714
30MP0003693_abnormal_embryo_hatching1.78920868
31MP0000383_abnormal_hair_follicle1.73539569
32MP0005408_hypopigmentation1.73445451
33MP0000465_gastrointestinal_hemorrhage1.73324015
34MP0001835_abnormal_antigen_presentation1.67062688
35MP0003121_genomic_imprinting1.65727564
36MP0002398_abnormal_bone_marrow1.64989425
37MP0009697_abnormal_copulation1.64231277
38MP0000647_abnormal_sebaceous_gland1.62609861
39MP0005464_abnormal_platelet_physiology1.61808643
40MP0004264_abnormal_extraembryonic_tissu1.61786634
41MP0001800_abnormal_humoral_immune1.54814316
42MP0010307_abnormal_tumor_latency1.54622745
43MP0010094_abnormal_chromosome_stability1.52328053
44MP0000015_abnormal_ear_pigmentation1.51355159
45MP0000703_abnormal_thymus_morphology1.50758143
46MP0002452_abnormal_antigen_presenting1.48232246
47MP0005671_abnormal_response_to1.46777644
48MP0010678_abnormal_skin_adnexa1.44588078
49MP0008007_abnormal_cellular_replicative1.40850931
50MP0002420_abnormal_adaptive_immunity1.39306652
51MP0001819_abnormal_immune_cell1.36990042
52MP0005000_abnormal_immune_tolerance1.36352689
53MP0000685_abnormal_immune_system1.35836800
54MP0002419_abnormal_innate_immunity1.33281428
55MP0003077_abnormal_cell_cycle1.33050435
56MP0004185_abnormal_adipocyte_glucose1.31915267
57MP0002723_abnormal_immune_serum1.30268273
58MP0003221_abnormal_cardiomyocyte_apopto1.29411158
59MP0003436_decreased_susceptibility_to1.29377335
60MP0005387_immune_system_phenotype1.28083516
61MP0001790_abnormal_immune_system1.28083516
62MP0002095_abnormal_skin_pigmentation1.27837614
63MP0001697_abnormal_embryo_size1.27345608
64MP0002722_abnormal_immune_system1.26544957
65MP0003172_abnormal_lysosome_physiology1.20898558
66MP0005423_abnormal_somatic_nervous1.19547047
67MP0000689_abnormal_spleen_morphology1.18038415
68MP0000716_abnormal_immune_system1.16007243
69MP0004147_increased_porphyrin_level1.12482188
70MP0000377_abnormal_hair_follicle1.11176264
71MP0000358_abnormal_cell_content/1.10509294
72MP0004947_skin_inflammation1.10151110
73MP0003567_abnormal_fetal_cardiomyocyte1.09215629
74MP0003705_abnormal_hypodermis_morpholog1.08703125
75MP0000371_diluted_coat_color1.07670753
76MP0005409_darkened_coat_color1.06563093
77MP0002098_abnormal_vibrissa_morphology1.04907692
78MP0002429_abnormal_blood_cell1.04215522
79MP0002405_respiratory_system_inflammati1.03516349
80MP0005025_abnormal_response_to1.02910535
81MP0005187_abnormal_penis_morphology1.01752996
82MP0003448_altered_tumor_morphology1.01439462
83MP0000733_abnormal_muscle_development1.01104451
84MP0000372_irregular_coat_pigmentation1.00356253
85MP0004381_abnormal_hair_follicle1.00245752
86MP0000350_abnormal_cell_proliferation0.98799532
87MP0003566_abnormal_cell_adhesion0.98134977
88MP0001915_intracranial_hemorrhage0.97664983
89MP0002086_abnormal_extraembryonic_tissu0.97029788
90MP0001730_embryonic_growth_arrest0.96524665
91MP0003091_abnormal_cell_migration0.96259224
92MP0001879_abnormal_lymphatic_vessel0.94473270
93MP0002877_abnormal_melanocyte_morpholog0.92220140
94MP0000858_altered_metastatic_potential0.91217732
95MP0010155_abnormal_intestine_physiology0.91181869
96MP0002080_prenatal_lethality0.90324568
97MP0002925_abnormal_cardiovascular_devel0.88197870
98MP0001216_abnormal_epidermal_layer0.86765519
99MP0003718_maternal_effect0.86413936
100MP0005248_abnormal_Harderian_gland0.86385580
101MP0004510_myositis0.85115298
102MP0002075_abnormal_coat/hair_pigmentati0.85059101
103MP0008961_abnormal_basal_metabolism0.83536901
104MP0004197_abnormal_fetal_growth/weight/0.83228459
105MP0000490_abnormal_crypts_of0.83206663
106MP0006054_spinal_hemorrhage0.82577963
107MP0004130_abnormal_muscle_cell0.82394114
108MP0002254_reproductive_system_inflammat0.82259552
109MP0005384_cellular_phenotype0.81815485
110MP0008770_decreased_survivor_rate0.81542605
111MP0002088_abnormal_embryonic_growth/wei0.80700348
112MP0003984_embryonic_growth_retardation0.80282190
113MP0004084_abnormal_cardiac_muscle0.80233910
114MP0003453_abnormal_keratinocyte_physiol0.79628257
115MP0003890_abnormal_embryonic-extraembry0.79520153
116MP0000013_abnormal_adipose_tissue0.78679555
117MP0001851_eye_inflammation0.77668582
118MP0005310_abnormal_salivary_gland0.77518134
119MP0001672_abnormal_embryogenesis/_devel0.77029230
120MP0005380_embryogenesis_phenotype0.77029230
121MP0010234_abnormal_vibrissa_follicle0.76224661
122MP0002092_abnormal_eye_morphology0.75682564
123MP0009785_altered_susceptibility_to0.75616269
124MP0000767_abnormal_smooth_muscle0.75387839
125MP0009703_decreased_birth_body0.75002679
126MP0000627_abnormal_mammary_gland0.74894299
127MP0002019_abnormal_tumor_incidence0.74325111
128MP0006035_abnormal_mitochondrial_morpho0.73773477
129MP0008775_abnormal_heart_ventricle0.73761737
130MP0001191_abnormal_skin_condition0.73284724
131MP0001186_pigmentation_phenotype0.73283446
132MP0003943_abnormal_hepatobiliary_system0.71998721
133MP0000313_abnormal_cell_death0.71715710
134MP0002332_abnormal_exercise_endurance0.71405241
135MP0005171_absent_coat_pigmentation0.71164815
136MP0000537_abnormal_urethra_morphology0.71079557
137MP0003646_muscle_fatigue0.70609047
138MP0002084_abnormal_developmental_patter0.70547240
139MP0002269_muscular_atrophy0.70248366
140MP0003045_fibrosis0.68950542
141MP0009115_abnormal_fat_cell0.68792477
142MP0002148_abnormal_hypersensitivity_rea0.68735618
143MP0001784_abnormal_fluid_regulation0.68735616
144MP0001929_abnormal_gametogenesis0.68513692
145MP0008932_abnormal_embryonic_tissue0.67808547
146MP0001293_anophthalmia0.67740617
147MP0005621_abnormal_cell_physiology0.67005362
148MP0005266_abnormal_metabolism0.64286498
149MP0000003_abnormal_adipose_tissue0.63509856
150MP0005395_other_phenotype0.63283701
151MP0005075_abnormal_melanosome_morpholog0.62852301
152MP0002160_abnormal_reproductive_system0.62237143
153MP0005501_abnormal_skin_physiology0.61825000
154MP0002085_abnormal_embryonic_tissue0.61361267
155MP0005253_abnormal_eye_physiology0.61315611

Predicted human phenotypes

RankGene SetZ-score
1Papillary thyroid carcinoma (HP:0002895)4.51194060
2Abnormality of the fingertips (HP:0001211)3.51758709
3Volvulus (HP:0002580)3.30498100
4Thyroid carcinoma (HP:0002890)3.20875449
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.12242556
6Short 4th metacarpal (HP:0010044)3.12242556
7Fair hair (HP:0002286)3.09981477
8Macroorchidism (HP:0000053)2.98780359
9Absent frontal sinuses (HP:0002688)2.96251737
10Abnormality of chromosome stability (HP:0003220)2.88968454
11Curly hair (HP:0002212)2.85196688
12Duplicated collecting system (HP:0000081)2.82993520
13Dysmetric saccades (HP:0000641)2.81458372
14Hypochromic microcytic anemia (HP:0004840)2.72185771
15Sandal gap (HP:0001852)2.66196777
16Generalized hypopigmentation of hair (HP:0011358)2.63560574
17Aplasia/Hypoplasia of the uvula (HP:0010293)2.60691511
18Gaze-evoked nystagmus (HP:0000640)2.58239025
19Insidious onset (HP:0003587)2.53510323
20Termporal pattern (HP:0011008)2.53510323
21Recurrent abscess formation (HP:0002722)2.51629391
22Absent/shortened dynein arms (HP:0200106)2.48699354
23Dynein arm defect of respiratory motile cilia (HP:0012255)2.48699354
24Trigonocephaly (HP:0000243)2.48613175
25T lymphocytopenia (HP:0005403)2.45806332
26Recurrent viral infections (HP:0004429)2.45566311
27Hyperventilation (HP:0002883)2.43800846
28Sparse lateral eyebrow (HP:0005338)2.37430591
29Abnormality of DNA repair (HP:0003254)2.37046344
30Birth length less than 3rd percentile (HP:0003561)2.33094114
31Acute myeloid leukemia (HP:0004808)2.28833442
32Abnormality of T cell number (HP:0011839)2.27845419
33Abnormality of the renal collecting system (HP:0004742)2.27830855
34Recurrent fungal infections (HP:0002841)2.27510155
35Prostate neoplasm (HP:0100787)2.27327905
36Abnormality of the renal cortex (HP:0011035)2.27001066
37Lip pit (HP:0100267)2.26669518
38Long eyelashes (HP:0000527)2.25837348
39Narrow palate (HP:0000189)2.24802963
40Heterotopia (HP:0002282)2.24255339
41Recurrent bacterial skin infections (HP:0005406)2.23116602
42Inappropriate behavior (HP:0000719)2.20924587
43Blue irides (HP:0000635)2.20465035
44Abnormality of the preputium (HP:0100587)2.17434147
45Hematochezia (HP:0002573)2.16600296
46Poikilocytosis (HP:0004447)2.15676931
47Acanthocytosis (HP:0001927)2.15162495
48Hyperkalemia (HP:0002153)2.14907835
49Eczematoid dermatitis (HP:0000976)2.13759746
50Ectopic kidney (HP:0000086)2.13388774
51Chromsome breakage (HP:0040012)2.12214552
52Chromosomal breakage induced by crosslinking agents (HP:0003221)2.11695894
53Myelodysplasia (HP:0002863)2.09321518
54Tubulointerstitial nephritis (HP:0001970)2.06528842
55Pheochromocytoma (HP:0002666)2.05505057
56Enlarged penis (HP:0000040)2.04846154
57Freckling (HP:0001480)2.03435201
58Abnormality of the heme biosynthetic pathway (HP:0010472)2.02629045
59Coarse hair (HP:0002208)2.00671327
60Sloping forehead (HP:0000340)2.00421888
61Cafe-au-lait spot (HP:0000957)2.00237955
62Entropion (HP:0000621)1.99089372
63Abnormality of the 4th metacarpal (HP:0010012)1.98371958
64Chronic hepatic failure (HP:0100626)1.98263105
65Deep philtrum (HP:0002002)1.97917835
66Thyroiditis (HP:0100646)1.96155405
67Cystic hygroma (HP:0000476)1.96108752
68Prominent nose (HP:0000448)1.95105171
69Aqueductal stenosis (HP:0002410)1.94947056
70Short chin (HP:0000331)1.93863119
71Submucous cleft hard palate (HP:0000176)1.93766355
72Smooth philtrum (HP:0000319)1.93475176
73Abnormal auditory evoked potentials (HP:0006958)1.92654291
74Abnormality of nail color (HP:0100643)1.91450327
75Papilledema (HP:0001085)1.91320768
76Disinhibition (HP:0000734)1.91283694
77Clubbing of toes (HP:0100760)1.91245171
78Abnormal ciliary motility (HP:0012262)1.90201163
79Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.89949998
80Obsessive-compulsive behavior (HP:0000722)1.87140646
81Increased nuchal translucency (HP:0010880)1.86728581
82Mediastinal lymphadenopathy (HP:0100721)1.86085702
83High pitched voice (HP:0001620)1.85880819
84Lower limb amyotrophy (HP:0007210)1.85440575
85Hypopigmentation of the fundus (HP:0007894)1.84816934
86Hypoplastic labia majora (HP:0000059)1.83834891
87Autoimmune hemolytic anemia (HP:0001890)1.83742321
88Urethral obstruction (HP:0000796)1.83617675
89Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.83614741
90Transitional cell carcinoma of the bladder (HP:0006740)1.83281886
91Hyperacusis (HP:0010780)1.82563193
92Cellulitis (HP:0100658)1.82268481
93Poor coordination (HP:0002370)1.82204392
94Periodontitis (HP:0000704)1.81696834
95Renal cortical cysts (HP:0000803)1.81476019
96Asymmetry of the thorax (HP:0001555)1.80194084
97Protruding tongue (HP:0010808)1.80116186
98Rhinitis (HP:0012384)1.80018886
99Septate vagina (HP:0001153)1.78159929
100Pancreatic cysts (HP:0001737)1.77907405
101Prolonged bleeding time (HP:0003010)1.77640983
102Chronic otitis media (HP:0000389)1.76974808
103Abnormality of oral frenula (HP:0000190)1.75264302
104Recurrent cutaneous fungal infections (HP:0011370)1.74958344
105Chronic mucocutaneous candidiasis (HP:0002728)1.74958344
106Increased density of long bones (HP:0006392)1.74905184
107Truncal obesity (HP:0001956)1.74798486
108Anhidrosis (HP:0000970)1.74533653
109Menstrual irregularities (HP:0000858)1.74263247
110Thick eyebrow (HP:0000574)1.73885234
111Gingival bleeding (HP:0000225)1.73569193
112Astrocytoma (HP:0009592)1.73300473
113Abnormality of the astrocytes (HP:0100707)1.73300473
114Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.72574150
115Abnormality of alanine metabolism (HP:0010916)1.72574150
116Hyperalaninemia (HP:0003348)1.72574150
117Abnormality of chromosome segregation (HP:0002916)1.71580057
118Central scotoma (HP:0000603)1.70921317
119Cutis marmorata (HP:0000965)1.69828308
120Abnormality of the ileum (HP:0001549)1.69655323
121Broad palm (HP:0001169)1.69330211
122Duodenal stenosis (HP:0100867)1.69311073
123Small intestinal stenosis (HP:0012848)1.69311073
124Meckel diverticulum (HP:0002245)1.69256112
125Bladder carcinoma (HP:0002862)1.69077603
126Bladder neoplasm (HP:0009725)1.69077603
127Horizontal nystagmus (HP:0000666)1.68426568
128Elfin facies (HP:0004428)1.68418655
129Cutaneous melanoma (HP:0012056)1.67982823
130Abnormality of the prostate (HP:0008775)1.67107894
131Abnormality of the carotid arteries (HP:0005344)1.66016805
132Oculomotor apraxia (HP:0000657)1.65998550
133Limited elbow extension (HP:0001377)1.64904846
134Nephroblastoma (Wilms tumor) (HP:0002667)1.64837389
135Abnormality of the labia majora (HP:0012881)1.64590775
136Absent speech (HP:0001344)1.63994562
137Arterial thrombosis (HP:0004420)1.63665752
138Breast carcinoma (HP:0003002)1.62865653
139Neoplasm of the thyroid gland (HP:0100031)1.62327300
140Abnormality of the right ventricle (HP:0001707)1.61556787
141Spinal cord lesions (HP:0100561)1.61547962
142Syringomyelia (HP:0003396)1.61547962
143Fatigue (HP:0012378)1.60911515
144Squamous cell carcinoma (HP:0002860)1.60652775
145Abnormal respiratory motile cilium physiology (HP:0012261)1.59459919
146Skull defect (HP:0001362)1.58044257
147Cerebral aneurysm (HP:0004944)1.57584244
148Astigmatism (HP:0000483)1.57367505
149Low anterior hairline (HP:0000294)1.57211960
150Gingivitis (HP:0000230)1.56866298
151Hypoplasia of the maxilla (HP:0000327)1.55056907
152Abnormality of the nasal septum (HP:0000419)1.54393413
153Abnormality of the frontal sinuses (HP:0002687)1.54245733
154Panhypogammaglobulinemia (HP:0003139)1.53682492
155Renovascular hypertension (HP:0100817)1.53614136
156Tapered finger (HP:0001182)1.53512980
157Acute lymphatic leukemia (HP:0006721)1.53461872
158Frequent falls (HP:0002359)1.53272147
159Amaurosis fugax (HP:0100576)1.52151534
160Deviation of the thumb (HP:0009603)1.50842363
161Supernumerary ribs (HP:0005815)1.50126102
162Cortical dysplasia (HP:0002539)1.49501229
163Ankyloglossia (HP:0010296)1.49414929
164Aplasia cutis congenita (HP:0001057)1.49382756
165Diplopia (HP:0000651)1.48899732
166Abnormality of binocular vision (HP:0011514)1.48899732
167Basal cell carcinoma (HP:0002671)1.48262619
168Long clavicles (HP:0000890)1.48104981
169Optic neuritis (HP:0100653)1.47138406
170Retrobulbar optic neuritis (HP:0100654)1.47138406
171Chronic obstructive pulmonary disease (HP:0006510)1.47088611
172Obstructive lung disease (HP:0006536)1.47088611
173Subacute progressive viral hepatitis (HP:0006572)1.47077899
174Proximal placement of thumb (HP:0009623)1.47039486

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK14.23982647
2CDK123.22602999
3EIF2AK32.38544018
4AKT32.35740119
5EEF2K2.34029818
6CDC72.29273614
7CAMK1G2.10604818
8SIK22.06103571
9ACVR1B2.02321363
10TXK2.01714090
11BRD41.92642747
12FGFR31.91516393
13CAMK1D1.90141851
14MST41.87652568
15TAOK31.86947079
16MAP4K11.83373397
17PRPF4B1.75720234
18FGFR21.72364383
19ERBB31.71542028
20MAP3K21.67286593
21STK101.67051616
22BRSK21.61337997
23CDK61.59238129
24SRPK11.58529895
25MAP3K141.58333077
26TSSK61.54101262
27STK41.50709132
28SCYL21.49655864
29BMPR1B1.49481654
30ITK1.48541047
31BLK1.44599541
32PDK21.37842892
33IRAK41.34233609
34RIPK11.33143216
35JAK11.32554288
36TYK21.31821553
37FER1.31571262
38NEK91.30412159
39TGFBR21.30386112
40MKNK11.29725959
41PDGFRB1.27538891
42CSF1R1.26011311
43HCK1.24735603
44WNK11.22464201
45PBK1.21933312
46JAK31.18763795
47FES1.17946284
48CLK11.14566062
49NEK21.12241855
50MAP3K101.09842707
51NUAK11.08776239
52MST1R1.07194902
53YES11.06206090
54ATR1.05532800
55TTK1.05311035
56PASK1.03909755
57LATS11.03080428
58PKN21.02375035
59SYK1.02361077
60CHUK1.01720060
61RAF11.01314698
62TEC0.99173246
63LCK0.98764130
64CSK0.96702240
65RIPK40.96057351
66TTN0.96056724
67MET0.95084347
68ALK0.94082656
69PRKAA20.93498119
70CAMKK20.93197603
71PTK60.92563772
72NEK60.91469286
73SGK30.90741365
74STK30.90667349
75KIT0.89655249
76KSR10.88905628
77MAP2K30.88521475
78PLK30.86222023
79MAP3K60.85770593
80BTK0.85102857
81IRAK10.84959827
82PNCK0.84198160
83STK390.83568519
84ATM0.82833470
85BMPR20.80271213
86MARK10.78680710
87NEK10.78514124
88CHEK20.76537411
89TRPM70.76474658
90FGFR10.76409154
91ERBB20.75511037
92CDK90.75302027
93PDGFRA0.74385729
94CHEK10.73186671
95CCNB10.71443796
96JAK20.69830861
97PRKAA10.69760215
98MKNK20.69488738
99TNK20.68259891
100FGR0.67795912
101EGFR0.67470108
102PLK20.65251828
103MAPK110.65069299
104MELK0.64914676
105PIM10.64515236
106CDK20.64159387
107WNK40.63982257
108MAPK140.63298804
109CSNK1D0.62765847
110PIK3CG0.61858706
111SGK20.61183466
112STK240.60479625
113PRKCH0.60192748
114PRKDC0.58964979
115RET0.58944590
116RPS6KB10.58939560
117TRIM280.58750528
118LRRK20.58729254
119BCR0.58110236
120EPHA30.57863291
121KSR20.56554192
122FGFR40.55254152
123PLK10.55227450
124AURKB0.54665794
125MTOR0.54447488
126WEE10.54255695
127MAP2K10.52894197
128ZAK0.52479075
129EPHB10.52457003
130MARK30.52162309
131* CDK10.51840590
132ICK0.51829338
133MAP3K40.51745459
134SGK10.51725180
135CSNK1A1L0.51338067
136MAP2K40.51317709
137PTK2B0.51111507
138CDK40.50946887
139SIK10.49271447
140FRK0.49252629
141RPS6KB20.49164858
142MAP3K70.48966994
143LYN0.48405403
144MAPK80.48397678
145BMX0.48197299
146AKT10.47463337
147EIF2AK20.46820032
148IGF1R0.46065154
149RPS6KA50.45184694
150TGFBR10.45123497
151FYN0.44511301
152CDK30.44472571
153NLK0.40059250
154MAP3K30.39703946

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034503.45632108
2Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.84450891
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.19725283
4Basal transcription factors_Homo sapiens_hsa030222.01623297
5One carbon pool by folate_Homo sapiens_hsa006701.73050765
6Circadian rhythm_Homo sapiens_hsa047101.69604915
7Selenocompound metabolism_Homo sapiens_hsa004501.65427547
8RNA transport_Homo sapiens_hsa030131.62508471
9Osteoclast differentiation_Homo sapiens_hsa043801.59774290
10Chronic myeloid leukemia_Homo sapiens_hsa052201.58500145
11B cell receptor signaling pathway_Homo sapiens_hsa046621.57308720
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.54309380
13Measles_Homo sapiens_hsa051621.53021651
14Leishmaniasis_Homo sapiens_hsa051401.51106085
15Nucleotide excision repair_Homo sapiens_hsa034201.49244304
16Systemic lupus erythematosus_Homo sapiens_hsa053221.48800384
17Thyroid cancer_Homo sapiens_hsa052161.45482204
18MicroRNAs in cancer_Homo sapiens_hsa052061.42976311
19T cell receptor signaling pathway_Homo sapiens_hsa046601.41203865
20Fatty acid biosynthesis_Homo sapiens_hsa000611.39078999
21Transcriptional misregulation in cancer_Homo sapiens_hsa052021.35772718
22Homologous recombination_Homo sapiens_hsa034401.30843676
23Lysine degradation_Homo sapiens_hsa003101.29231128
24Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.27366010
25Dorso-ventral axis formation_Homo sapiens_hsa043201.27233654
26Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.26978334
27Nitrogen metabolism_Homo sapiens_hsa009101.24881562
28Small cell lung cancer_Homo sapiens_hsa052221.24721717
29Viral myocarditis_Homo sapiens_hsa054161.20959765
30Herpes simplex infection_Homo sapiens_hsa051681.20700103
31Primary immunodeficiency_Homo sapiens_hsa053401.20330168
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.20175582
33Chemokine signaling pathway_Homo sapiens_hsa040621.19933472
34Non-small cell lung cancer_Homo sapiens_hsa052231.17747863
35Adherens junction_Homo sapiens_hsa045201.17093395
36Cell cycle_Homo sapiens_hsa041101.16843183
37Viral carcinogenesis_Homo sapiens_hsa052031.15772012
38Pancreatic cancer_Homo sapiens_hsa052121.15060827
39Hepatitis B_Homo sapiens_hsa051611.14573127
40Platelet activation_Homo sapiens_hsa046111.13067438
41Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.12636863
42Glioma_Homo sapiens_hsa052141.12443401
43Hematopoietic cell lineage_Homo sapiens_hsa046401.11702959
44Toll-like receptor signaling pathway_Homo sapiens_hsa046201.10180131
45Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.09758275
46Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.09037659
47Sphingolipid metabolism_Homo sapiens_hsa006001.06151689
48HTLV-I infection_Homo sapiens_hsa051661.04943667
49Jak-STAT signaling pathway_Homo sapiens_hsa046301.02978118
50Leukocyte transendothelial migration_Homo sapiens_hsa046701.02815084
51Prostate cancer_Homo sapiens_hsa052151.02636119
52Toxoplasmosis_Homo sapiens_hsa051451.02430675
53Proteoglycans in cancer_Homo sapiens_hsa052051.00578507
54Thyroid hormone signaling pathway_Homo sapiens_hsa049190.96858037
55ABC transporters_Homo sapiens_hsa020100.96015830
56Influenza A_Homo sapiens_hsa051640.95402495
57Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.94975315
58mTOR signaling pathway_Homo sapiens_hsa041500.94958583
59Neurotrophin signaling pathway_Homo sapiens_hsa047220.93997563
60NOD-like receptor signaling pathway_Homo sapiens_hsa046210.93569405
61Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93342373
62Endometrial cancer_Homo sapiens_hsa052130.93113603
63Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92608585
64Colorectal cancer_Homo sapiens_hsa052100.92336561
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.92317820
66Acute myeloid leukemia_Homo sapiens_hsa052210.91054090
67Antigen processing and presentation_Homo sapiens_hsa046120.90960922
68TGF-beta signaling pathway_Homo sapiens_hsa043500.90300584
69Mismatch repair_Homo sapiens_hsa034300.90144279
70Type II diabetes mellitus_Homo sapiens_hsa049300.88768557
71Apoptosis_Homo sapiens_hsa042100.87847266
72Tuberculosis_Homo sapiens_hsa051520.87727747
73RNA degradation_Homo sapiens_hsa030180.87678987
74TNF signaling pathway_Homo sapiens_hsa046680.87367356
75Longevity regulating pathway - mammal_Homo sapiens_hsa042110.87130693
76FoxO signaling pathway_Homo sapiens_hsa040680.86593591
77Insulin signaling pathway_Homo sapiens_hsa049100.86384045
78Graft-versus-host disease_Homo sapiens_hsa053320.85603503
79Insulin resistance_Homo sapiens_hsa049310.84149069
80Notch signaling pathway_Homo sapiens_hsa043300.83638361
81Intestinal immune network for IgA production_Homo sapiens_hsa046720.83273642
82Allograft rejection_Homo sapiens_hsa053300.82189400
83Alcoholism_Homo sapiens_hsa050340.81349651
84Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.81257705
85Axon guidance_Homo sapiens_hsa043600.80490896
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79312911
87Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.78559102
88AMPK signaling pathway_Homo sapiens_hsa041520.78392230
89Renal cell carcinoma_Homo sapiens_hsa052110.76389744
90ErbB signaling pathway_Homo sapiens_hsa040120.76335164
91Propanoate metabolism_Homo sapiens_hsa006400.76056242
92Salmonella infection_Homo sapiens_hsa051320.75957629
93p53 signaling pathway_Homo sapiens_hsa041150.75632409
94Focal adhesion_Homo sapiens_hsa045100.75608715
95Prolactin signaling pathway_Homo sapiens_hsa049170.74682531
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.73281655
97Pathways in cancer_Homo sapiens_hsa052000.72931409
98MAPK signaling pathway_Homo sapiens_hsa040100.72131607
99Hepatitis C_Homo sapiens_hsa051600.71614975
100mRNA surveillance pathway_Homo sapiens_hsa030150.71444574
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.71114750
102Rap1 signaling pathway_Homo sapiens_hsa040150.69896504
103Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69480337
104Estrogen signaling pathway_Homo sapiens_hsa049150.69424260
105Oocyte meiosis_Homo sapiens_hsa041140.68972708
106Choline metabolism in cancer_Homo sapiens_hsa052310.68794609
107Type I diabetes mellitus_Homo sapiens_hsa049400.68767360
108Long-term potentiation_Homo sapiens_hsa047200.68450493
109VEGF signaling pathway_Homo sapiens_hsa043700.68147891
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.68117425
111Long-term depression_Homo sapiens_hsa047300.68053574
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67746735
113GnRH signaling pathway_Homo sapiens_hsa049120.67620777
114Inositol phosphate metabolism_Homo sapiens_hsa005620.67196671
115Basal cell carcinoma_Homo sapiens_hsa052170.66528616
116Malaria_Homo sapiens_hsa051440.66353115
117DNA replication_Homo sapiens_hsa030300.65936272
118Pertussis_Homo sapiens_hsa051330.63786365
119Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.63490142
120Fanconi anemia pathway_Homo sapiens_hsa034600.62187686
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.61832578
122Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.61122651
123Bladder cancer_Homo sapiens_hsa052190.60555863
124HIF-1 signaling pathway_Homo sapiens_hsa040660.60327839
125Melanoma_Homo sapiens_hsa052180.60002737
126Renin secretion_Homo sapiens_hsa049240.59885664
127Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.59390093
128Staphylococcus aureus infection_Homo sapiens_hsa051500.58853975
129Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.58342672
130Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58106366
131Wnt signaling pathway_Homo sapiens_hsa043100.58043981
132Central carbon metabolism in cancer_Homo sapiens_hsa052300.57250001
133Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55954410
134N-Glycan biosynthesis_Homo sapiens_hsa005100.45986650
135Tight junction_Homo sapiens_hsa045300.45188122
136Spliceosome_Homo sapiens_hsa030400.43369996
137Adipocytokine signaling pathway_Homo sapiens_hsa049200.43164026
138Hippo signaling pathway_Homo sapiens_hsa043900.40299302
139Steroid biosynthesis_Homo sapiens_hsa001000.40135595
140Ether lipid metabolism_Homo sapiens_hsa005650.39905794
141Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39885724
142Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37775176
143Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36812016

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