GART

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.64229831
2DNA strand elongation involved in DNA replication (GO:0006271)5.01908341
3DNA replication initiation (GO:0006270)4.99175563
4DNA strand elongation (GO:0022616)4.75786826
5protein localization to kinetochore (GO:0034501)4.59029342
6nuclear pore organization (GO:0006999)4.56581223
7maturation of SSU-rRNA (GO:0030490)4.47432321
8telomere maintenance via semi-conservative replication (GO:0032201)4.38838226
9formation of translation preinitiation complex (GO:0001731)4.38226211
10DNA replication-dependent nucleosome organization (GO:0034723)4.35791236
11DNA replication-dependent nucleosome assembly (GO:0006335)4.35791236
12* folic acid-containing compound biosynthetic process (GO:0009396)4.30708737
13nuclear pore complex assembly (GO:0051292)4.29053293
14mitotic nuclear envelope disassembly (GO:0007077)4.28524037
15* nucleobase biosynthetic process (GO:0046112)4.22662135
16ribosomal small subunit assembly (GO:0000028)4.11545096
17ribosome assembly (GO:0042255)4.00947094
18nuclear envelope disassembly (GO:0051081)3.97608662
19membrane disassembly (GO:0030397)3.97608662
20viral transcription (GO:0019083)3.97501431
21DNA replication checkpoint (GO:0000076)3.95921934
22translational termination (GO:0006415)3.94605208
23mitotic sister chromatid cohesion (GO:0007064)3.94509176
24ribosomal large subunit biogenesis (GO:0042273)3.93886304
25* IMP biosynthetic process (GO:0006188)3.90008785
26regulation of gene silencing by RNA (GO:0060966)3.86733637
27regulation of posttranscriptional gene silencing (GO:0060147)3.86733637
28regulation of gene silencing by miRNA (GO:0060964)3.86733637
29DNA duplex unwinding (GO:0032508)3.86580353
30ribosome biogenesis (GO:0042254)3.85427860
31DNA geometric change (GO:0032392)3.84142794
32telomere maintenance via recombination (GO:0000722)3.82552156
33protein localization to chromosome, centromeric region (GO:0071459)3.78088873
34mitotic metaphase plate congression (GO:0007080)3.75020499
35double-strand break repair via nonhomologous end joining (GO:0006303)3.74342322
36non-recombinational repair (GO:0000726)3.74342322
37ribonucleoprotein complex biogenesis (GO:0022613)3.73968366
38tRNA aminoacylation (GO:0043039)3.72488865
39amino acid activation (GO:0043038)3.72488865
40mitotic recombination (GO:0006312)3.70771690
41translational elongation (GO:0006414)3.68660904
42translational initiation (GO:0006413)3.67412540
43DNA topological change (GO:0006265)3.65166418
44regulation of translational fidelity (GO:0006450)3.63575585
45telomere maintenance via telomere lengthening (GO:0010833)3.56857684
46* IMP metabolic process (GO:0046040)3.50604547
47nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.49562895
48ribosomal small subunit biogenesis (GO:0042274)3.49015741
49nucleotide-excision repair, DNA gap filling (GO:0006297)3.44601960
50somatic hypermutation of immunoglobulin genes (GO:0016446)3.44223283
51somatic diversification of immune receptors via somatic mutation (GO:0002566)3.44223283
52L-serine metabolic process (GO:0006563)3.43632140
53regulation of histone H3-K9 methylation (GO:0051570)3.42975769
54meiotic chromosome segregation (GO:0045132)3.40895451
55establishment of viral latency (GO:0019043)3.40011886
56rRNA processing (GO:0006364)3.39705736
57spliceosomal snRNP assembly (GO:0000387)3.38941309
58regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.38661177
59DNA ligation (GO:0006266)3.37112278
60chromatin remodeling at centromere (GO:0031055)3.36887523
61* purine nucleobase biosynthetic process (GO:0009113)3.35695956
62regulation of translational termination (GO:0006449)3.34512253
63mitotic sister chromatid segregation (GO:0000070)3.33236036
64regulation of helicase activity (GO:0051095)3.32675530
65rRNA metabolic process (GO:0016072)3.28739492
66CENP-A containing nucleosome assembly (GO:0034080)3.26785845
67pore complex assembly (GO:0046931)3.25348109
68metaphase plate congression (GO:0051310)3.25111225
69regulation of spindle organization (GO:0090224)3.23982584
70mitotic chromosome condensation (GO:0007076)3.23821485
71regulation of centriole replication (GO:0046599)3.22423765
72peptidyl-arginine omega-N-methylation (GO:0035247)3.22416517
73negative regulation of chromosome segregation (GO:0051985)3.22073441
74negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.20549478
75establishment of integrated proviral latency (GO:0075713)3.20097469
76heterochromatin organization (GO:0070828)3.20082224
77regulation of chromosome segregation (GO:0051983)3.19479114
78negative regulation of histone methylation (GO:0031061)3.18828760
79DNA replication-independent nucleosome assembly (GO:0006336)3.18445367
80DNA replication-independent nucleosome organization (GO:0034724)3.18445367
81folic acid metabolic process (GO:0046655)3.17124402
82regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.14219510
83protein complex localization (GO:0031503)3.14139978
84SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.13587110
85cellular protein complex disassembly (GO:0043624)3.13261070
86mitochondrial RNA metabolic process (GO:0000959)3.12917917
87mitotic spindle checkpoint (GO:0071174)3.12879227
88spindle checkpoint (GO:0031577)3.12602674
89negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.12336440
90negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.12336440
91negative regulation of mitotic sister chromatid segregation (GO:0033048)3.12336440
92negative regulation of mitotic sister chromatid separation (GO:2000816)3.12336440
93negative regulation of sister chromatid segregation (GO:0033046)3.12336440
94positive regulation of chromosome segregation (GO:0051984)3.12111770
95sister chromatid segregation (GO:0000819)3.11764637
96DNA deamination (GO:0045006)3.10923546
97nuclear envelope organization (GO:0006998)3.09646832
98regulation of translational elongation (GO:0006448)3.08719990
99pre-miRNA processing (GO:0031054)3.08109687
100viral life cycle (GO:0019058)3.06336352
101negative regulation of mRNA processing (GO:0050686)3.06107445
102protein targeting to ER (GO:0045047)3.04553039
103pseudouridine synthesis (GO:0001522)3.04251963
104cotranslational protein targeting to membrane (GO:0006613)3.04047595
105chromosome segregation (GO:0007059)3.03286685
106regulation of mitotic metaphase/anaphase transition (GO:0030071)3.01829046
107regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.01829046
108maturation of 5.8S rRNA (GO:0000460)3.01656632
109DNA conformation change (GO:0071103)3.01279788
110histone exchange (GO:0043486)3.00359194
111chromatin assembly or disassembly (GO:0006333)2.99570725
112mitotic spindle assembly checkpoint (GO:0007094)2.99254370
113translesion synthesis (GO:0019985)2.98733088
114telomere maintenance (GO:0000723)2.97897995
115viral mRNA export from host cell nucleus (GO:0046784)2.97106305
116mRNA splicing, via spliceosome (GO:0000398)2.96972919
117RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.96972919
118RNA splicing, via transesterification reactions (GO:0000375)2.96233295
119telomere organization (GO:0032200)2.96022502
120protein complex disassembly (GO:0043241)2.95372318
121DNA synthesis involved in DNA repair (GO:0000731)2.95328566
122negative regulation of RNA splicing (GO:0033119)2.95112892
123mismatch repair (GO:0006298)2.94837366
124spindle assembly checkpoint (GO:0071173)2.94517532
125histone arginine methylation (GO:0034969)2.94505869
126proteasome assembly (GO:0043248)2.94246393
127regulation of centrosome cycle (GO:0046605)2.93713814
128regulation of mitotic sister chromatid separation (GO:0010965)2.93498680
129regulation of mitotic sister chromatid segregation (GO:0033047)2.93498680
130regulation of sister chromatid segregation (GO:0033045)2.93498680
131kinetochore organization (GO:0051383)2.92824825
132nucleobase-containing small molecule interconversion (GO:0015949)2.92535601
133chromosome condensation (GO:0030261)2.91749528
134DNA catabolic process, exonucleolytic (GO:0000738)2.91719695
135postreplication repair (GO:0006301)2.90287364
136establishment of protein localization to endoplasmic reticulum (GO:0072599)2.89189828
137attachment of spindle microtubules to kinetochore (GO:0008608)2.89175111
138establishment of chromosome localization (GO:0051303)2.88864941
139tRNA aminoacylation for protein translation (GO:0006418)2.87817307
140regulation of mitotic spindle organization (GO:0060236)2.87404122
141dosage compensation (GO:0007549)2.85888095
142spliceosomal tri-snRNP complex assembly (GO:0000244)2.85378007
143nuclear-transcribed mRNA catabolic process (GO:0000956)2.84950706

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.33576748
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.36522523
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.92460905
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.71633570
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.51906807
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.19534047
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.86146586
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83507450
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.71414673
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.48261519
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.41568221
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.38778852
13* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.32136253
14* XRN2_22483619_ChIP-Seq_HELA_Human2.29833908
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.25224326
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.24482984
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.20943402
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.16489475
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14001911
20AR_21909140_ChIP-Seq_LNCAP_Human2.02953288
21* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.01156302
22MYC_22102868_ChIP-Seq_BL_Human1.94665569
23* E2F1_21310950_ChIP-Seq_MCF-7_Human1.92920299
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92069528
25E2F1_18555785_ChIP-Seq_MESCs_Mouse1.89389294
26NANOG_18555785_ChIP-Seq_MESCs_Mouse1.87538383
27POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.87083533
28* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.85716627
29* VDR_23849224_ChIP-Seq_CD4+_Human1.85087671
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.84788899
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.82800949
32SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.82745953
33POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.82681247
34FOXP3_21729870_ChIP-Seq_TREG_Human1.74612588
35DCP1A_22483619_ChIP-Seq_HELA_Human1.70280011
36TTF2_22483619_ChIP-Seq_HELA_Human1.67981783
37NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.65297252
38* GABP_19822575_ChIP-Seq_HepG2_Human1.62895323
39THAP11_20581084_ChIP-Seq_MESCs_Mouse1.60545195
40STAT3_1855785_ChIP-Seq_MESCs_Mouse1.60121707
41ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56036893
42* CIITA_25753668_ChIP-Seq_RAJI_Human1.55074076
43PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.51969805
44ELF1_17652178_ChIP-ChIP_JURKAT_Human1.51029742
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.50059786
46KDM5A_27292631_Chip-Seq_BREAST_Human1.47702831
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46874187
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44855321
49SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.43148048
50SALL1_21062744_ChIP-ChIP_HESCs_Human1.40892744
51* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.40537453
52SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.40160581
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.34911554
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.34666185
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32810943
56* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.32008145
57SOX2_18555785_ChIP-Seq_MESCs_Mouse1.30982948
58FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.29502251
59ELK1_19687146_ChIP-ChIP_HELA_Human1.29421724
60* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29045030
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.28103094
62KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.26631993
63KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.26631993
64KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.26631993
65* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.25022395
66ESR1_15608294_ChIP-ChIP_MCF-7_Human1.24966379
67TCF3_18692474_ChIP-Seq_MEFs_Mouse1.20790877
68FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20512380
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.18952023
70HOXB4_20404135_ChIP-ChIP_EML_Mouse1.18853407
71DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17888871
72TFEB_21752829_ChIP-Seq_HELA_Human1.15746369
73KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.15596586
74VDR_21846776_ChIP-Seq_THP-1_Human1.15504210
75SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.12432825
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10250114
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09676294
78CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.08429177
79ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07014849
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06795712
81NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.06584443
82TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05489146
83ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.03693614
84NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.03417336
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01979579
86MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01787183
87SOX17_20123909_ChIP-Seq_XEN_Mouse1.00788594
88PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99067847
89NANOG_21062744_ChIP-ChIP_HESCs_Human0.98231004
90TP63_19390658_ChIP-ChIP_HaCaT_Human0.94889132
91CHD1_26751641_Chip-Seq_LNCaP_Human0.93480482
92OCT4_18692474_ChIP-Seq_MEFs_Mouse0.93347748
93CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92674702
94SOX2_18692474_ChIP-Seq_MEFs_Mouse0.92584702
95FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.92045250
96TCF3_18692474_ChIP-Seq_MESCs_Mouse0.91586795
97* SRF_21415370_ChIP-Seq_HL-1_Mouse0.91459115
98BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90456565
99NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.90049863
100RBPJ_22232070_ChIP-Seq_NCS_Mouse0.88761219
101CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88199681
102CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.87930090
103HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.85863953
104ZNF263_19887448_ChIP-Seq_K562_Human0.85349931
105ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.85308220
106CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.84802109
107* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.84468827
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.84397448
109* NANOG_16153702_ChIP-ChIP_HESCs_Human0.83587057
110MYC_18940864_ChIP-ChIP_HL60_Human0.82562354
111CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82077265
112HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.80675121
113SOX2_16153702_ChIP-ChIP_HESCs_Human0.76837994
114TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.76532828
115* SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.76194714
116* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.75217361
117SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.74793486
118* DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.71783578
119NOTCH1_21737748_ChIP-Seq_TLL_Human0.68941821
120SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.66842379

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.94389880
2MP0010094_abnormal_chromosome_stability4.66526456
3MP0003111_abnormal_nucleus_morphology4.56747302
4MP0004957_abnormal_blastocyst_morpholog4.51447629
5MP0008057_abnormal_DNA_replication4.07348228
6MP0003077_abnormal_cell_cycle3.95083449
7MP0008058_abnormal_DNA_repair3.03246361
8MP0010352_gastrointestinal_tract_polyps2.99789484
9MP0001730_embryonic_growth_arrest2.77445128
10MP0008007_abnormal_cellular_replicative2.61838325
11MP0008932_abnormal_embryonic_tissue2.58250623
12MP0009697_abnormal_copulation2.57235871
13MP0003806_abnormal_nucleotide_metabolis2.56485762
14MP0000350_abnormal_cell_proliferation2.49859358
15MP0003123_paternal_imprinting2.39579849
16MP0002396_abnormal_hematopoietic_system2.28410245
17MP0010307_abnormal_tumor_latency2.26310539
18MP0001672_abnormal_embryogenesis/_devel2.02292627
19MP0005380_embryogenesis_phenotype2.02292627
20MP0001697_abnormal_embryo_size1.95227924
21MP0002877_abnormal_melanocyte_morpholog1.87326846
22MP0002080_prenatal_lethality1.83733016
23MP0003984_embryonic_growth_retardation1.83581888
24MP0002084_abnormal_developmental_patter1.81324960
25MP0002085_abnormal_embryonic_tissue1.80485777
26MP0002088_abnormal_embryonic_growth/wei1.80370667
27MP0004197_abnormal_fetal_growth/weight/1.77944109
28MP0003786_premature_aging1.74729736
29MP0008877_abnormal_DNA_methylation1.72600202
30MP0002086_abnormal_extraembryonic_tissu1.68890896
31MP0000490_abnormal_crypts_of1.68215174
32MP0005076_abnormal_cell_differentiation1.64197014
33MP0001661_extended_life_span1.59630906
34MP0003567_abnormal_fetal_cardiomyocyte1.51911291
35MP0006035_abnormal_mitochondrial_morpho1.48908849
36MP0000313_abnormal_cell_death1.48835401
37MP0003705_abnormal_hypodermis_morpholog1.48313221
38MP0004147_increased_porphyrin_level1.46897366
39MP0002019_abnormal_tumor_incidence1.44803548
40MP0004133_heterotaxia1.37234790
41MP0000537_abnormal_urethra_morphology1.36591523
42MP0003890_abnormal_embryonic-extraembry1.34272956
43MP0004808_abnormal_hematopoietic_stem1.33738432
44MP0001293_anophthalmia1.32811816
45MP0002009_preneoplasia1.32088875
46MP0010030_abnormal_orbit_morphology1.28762043
47MP0003718_maternal_effect1.25586555
48MP0003566_abnormal_cell_adhesion1.20439318
49MP0003119_abnormal_digestive_system1.17004882
50MP0003121_genomic_imprinting1.16165832
51MP0009672_abnormal_birth_weight1.12699157
52MP0009333_abnormal_splenocyte_physiolog1.06943233
53MP0000703_abnormal_thymus_morphology1.05030030
54MP0002653_abnormal_ependyma_morphology1.03781037
55MP0002210_abnormal_sex_determination1.01493024
56MP0009053_abnormal_anal_canal1.00953399
57MP0000358_abnormal_cell_content/1.00327263
58MP0006036_abnormal_mitochondrial_physio0.97696565
59MP0005023_abnormal_wound_healing0.96866290
60MP0001145_abnormal_male_reproductive0.96186294
61MP0005397_hematopoietic_system_phenotyp0.96035059
62MP0001545_abnormal_hematopoietic_system0.96035059
63MP0001915_intracranial_hemorrhage0.96004168
64MP0002111_abnormal_tail_morphology0.93304752
65MP0003763_abnormal_thymus_physiology0.92019885
66MP0002722_abnormal_immune_system0.91424866
67MP0003315_abnormal_perineum_morphology0.91082597
68MP0001849_ear_inflammation0.89307762
69MP0009703_decreased_birth_body0.87870276
70MP0002398_abnormal_bone_marrow0.85565596
71MP0000689_abnormal_spleen_morphology0.85353062
72MP0008995_early_reproductive_senescence0.84550925
73MP0005384_cellular_phenotype0.83921611
74MP0000858_altered_metastatic_potential0.83359808
75MP0003221_abnormal_cardiomyocyte_apopto0.82709854
76MP0003656_abnormal_erythrocyte_physiolo0.82271584
77MP0002160_abnormal_reproductive_system0.82164223
78MP0002938_white_spotting0.80712411
79MP0005187_abnormal_penis_morphology0.80164057
80MP0005621_abnormal_cell_physiology0.79887270
81MP0000428_abnormal_craniofacial_morphol0.79658843
82MP0002092_abnormal_eye_morphology0.78757579
83MP0000647_abnormal_sebaceous_gland0.78623180
84MP0009278_abnormal_bone_marrow0.77644813
85MP0000477_abnormal_intestine_morphology0.77392252
86MP0000372_irregular_coat_pigmentation0.76800608
87MP0004264_abnormal_extraembryonic_tissu0.76078044
88MP0001529_abnormal_vocalization0.75655916
89MP0001346_abnormal_lacrimal_gland0.75507725
90MP0000579_abnormal_nail_morphology0.73943583
91MP0000678_abnormal_parathyroid_gland0.73401275
92MP0000653_abnormal_sex_gland0.73358250
93MP0005171_absent_coat_pigmentation0.72712031
94MP0005266_abnormal_metabolism0.72696665
95MP0006054_spinal_hemorrhage0.72604215
96MP0001929_abnormal_gametogenesis0.72366619
97MP0002697_abnormal_eye_size0.70925829
98MP0001881_abnormal_mammary_gland0.70905497
99MP0005501_abnormal_skin_physiology0.70666399
100MP0003937_abnormal_limbs/digits/tail_de0.69189807
101MP0005408_hypopigmentation0.68476598
102MP0003186_abnormal_redox_activity0.68432141
103MP0003943_abnormal_hepatobiliary_system0.68138095
104MP0002429_abnormal_blood_cell0.67083388
105MP0002796_impaired_skin_barrier0.66579394
106MP0003699_abnormal_female_reproductive0.66050921
107MP0001286_abnormal_eye_development0.65450077
108MP0003385_abnormal_body_wall0.64170389
109MP0004185_abnormal_adipocyte_glucose0.64110984
110MP0008770_decreased_survivor_rate0.63887142
111MP0006292_abnormal_olfactory_placode0.62186212
112MP0001727_abnormal_embryo_implantation0.61096072
113MP0004233_abnormal_muscle_weight0.59975576
114MP0003941_abnormal_skin_development0.59631043
115MP0000733_abnormal_muscle_development0.59481285
116MP0005451_abnormal_body_composition0.57807449
117MP0003698_abnormal_male_reproductive0.57558990
118MP0001119_abnormal_female_reproductive0.57366238
119MP0005389_reproductive_system_phenotype0.57267363
120MP0002925_abnormal_cardiovascular_devel0.57228005
121MP0002161_abnormal_fertility/fecundity0.55857064
122MP0003283_abnormal_digestive_organ0.55159975
123MP0000750_abnormal_muscle_regeneration0.54602569
124MP0002060_abnormal_skin_morphology0.54457142
125MP0005395_other_phenotype0.54146108
126MP0003861_abnormal_nervous_system0.52771721
127MP0001216_abnormal_epidermal_layer0.52499165
128MP0001853_heart_inflammation0.51281345
129MP0000432_abnormal_head_morphology0.50698521
130MP0002269_muscular_atrophy0.50385960
131MP0010234_abnormal_vibrissa_follicle0.49379946
132MP0000266_abnormal_heart_morphology0.49134787

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.83461888
2Birth length less than 3rd percentile (HP:0003561)4.33685117
3Reticulocytopenia (HP:0001896)4.32791716
4Selective tooth agenesis (HP:0001592)3.96595796
5Medulloblastoma (HP:0002885)3.92831043
6Colon cancer (HP:0003003)3.90735988
7Abnormality of glycolysis (HP:0004366)3.68368843
8Abnormality of cells of the erythroid lineage (HP:0012130)3.63202160
9Oral leukoplakia (HP:0002745)3.62208367
10Microvesicular hepatic steatosis (HP:0001414)3.52472099
11Agnosia (HP:0010524)3.42736651
12Breast hypoplasia (HP:0003187)3.39357933
13Chromsome breakage (HP:0040012)3.33039682
14Increased serum pyruvate (HP:0003542)3.30532871
15Abnormal number of erythroid precursors (HP:0012131)3.28327734
16Cortical dysplasia (HP:0002539)3.21661186
17Astrocytoma (HP:0009592)3.17447620
18Abnormality of the astrocytes (HP:0100707)3.17447620
19Rhabdomyosarcoma (HP:0002859)3.15060610
20Chromosomal breakage induced by crosslinking agents (HP:0003221)3.14627221
21Abnormality of the labia minora (HP:0012880)3.00075125
22Abnormal gallbladder physiology (HP:0012438)2.92377654
23Cholecystitis (HP:0001082)2.92377654
24Basal cell carcinoma (HP:0002671)2.91587998
25Degeneration of anterior horn cells (HP:0002398)2.90344533
26Abnormality of the anterior horn cell (HP:0006802)2.90344533
27Abnormal number of incisors (HP:0011064)2.83331947
28Patellar aplasia (HP:0006443)2.81078558
29Neoplasm of the pancreas (HP:0002894)2.78405331
30Macrocytic anemia (HP:0001972)2.78151105
31Abnormality of chromosome stability (HP:0003220)2.75814702
32Glioma (HP:0009733)2.74768191
33Absent thumb (HP:0009777)2.71715485
34Neoplasm of the oral cavity (HP:0100649)2.71630834
35Rough bone trabeculation (HP:0100670)2.68768736
36Absent radius (HP:0003974)2.67099081
37Nephroblastoma (Wilms tumor) (HP:0002667)2.66535587
38Cerebral hypomyelination (HP:0006808)2.63036715
39Aplasia/Hypoplasia of the patella (HP:0006498)2.62856937
40Carpal bone hypoplasia (HP:0001498)2.62615232
41Neoplasm of striated muscle (HP:0009728)2.60264304
42Missing ribs (HP:0000921)2.59638157
43Abnormality of the preputium (HP:0100587)2.56334917
44Proximal placement of thumb (HP:0009623)2.56014265
45Meckel diverticulum (HP:0002245)2.55488085
46Aplastic anemia (HP:0001915)2.55033471
47Multiple enchondromatosis (HP:0005701)2.53596860
48Biliary tract neoplasm (HP:0100574)2.52524638
49Impulsivity (HP:0100710)2.52518210
50Trismus (HP:0000211)2.50988482
51Deviation of the thumb (HP:0009603)2.47749643
52Absent forearm bone (HP:0003953)2.46809457
53Aplasia involving forearm bones (HP:0009822)2.46809457
5411 pairs of ribs (HP:0000878)2.46690453
55Abnormality of the ileum (HP:0001549)2.46537728
56Pallor (HP:0000980)2.46353949
57Embryonal renal neoplasm (HP:0011794)2.45512139
58Myelodysplasia (HP:0002863)2.43343375
59Amaurosis fugax (HP:0100576)2.41958911
60Angiofibromas (HP:0010615)2.40304353
61Adenoma sebaceum (HP:0009720)2.40304353
62Aplasia/Hypoplasia of the uvula (HP:0010293)2.36578637
63Progressive muscle weakness (HP:0003323)2.32512683
64Supernumerary spleens (HP:0009799)2.32432000
65Premature graying of hair (HP:0002216)2.27980769
66Volvulus (HP:0002580)2.26077510
67Abnormality of pyrimidine metabolism (HP:0004353)2.25113655
68Increased nuchal translucency (HP:0010880)2.23999617
69Progressive external ophthalmoplegia (HP:0000590)2.23076624
70Tracheoesophageal fistula (HP:0002575)2.18774517
71Atresia of the external auditory canal (HP:0000413)2.18565077
72Abnormality of cochlea (HP:0000375)2.16080305
73Small intestinal stenosis (HP:0012848)2.13523259
74Duodenal stenosis (HP:0100867)2.13523259
75Cellular immunodeficiency (HP:0005374)2.12994255
76Neoplasm of the colon (HP:0100273)2.11549116
77Thrombocytosis (HP:0001894)2.11515133
78Horseshoe kidney (HP:0000085)2.11493852
79Bone marrow hypocellularity (HP:0005528)2.10771074
80Asplenia (HP:0001746)2.10751411
81Abnormality of abdominal situs (HP:0011620)2.10334457
82Abdominal situs inversus (HP:0003363)2.10334457
83Abnormality of methionine metabolism (HP:0010901)2.09868424
84Cafe-au-lait spot (HP:0000957)2.09046294
85Choanal atresia (HP:0000453)2.08778966
86Aplasia/hypoplasia of the humerus (HP:0006507)2.07858767
87Squamous cell carcinoma (HP:0002860)2.06997185
88Premature ovarian failure (HP:0008209)2.05306913
89Abnormality of reticulocytes (HP:0004312)2.03869548
90Sloping forehead (HP:0000340)2.03406525
91Prominent nose (HP:0000448)2.03341194
92Ovarian neoplasm (HP:0100615)2.02359032
93Hypoplasia of the pons (HP:0012110)2.01677598
94Abnormality of homocysteine metabolism (HP:0010919)1.99927637
95Homocystinuria (HP:0002156)1.99927637
96Abnormality of the pons (HP:0007361)1.99875479
97Upper limb muscle weakness (HP:0003484)1.99422950
98Type I transferrin isoform profile (HP:0003642)1.97104973
99High pitched voice (HP:0001620)1.96924858
100Aplasia/Hypoplasia of the spleen (HP:0010451)1.96672174
101Microretrognathia (HP:0000308)1.96306444
102Abnormality of the calcaneus (HP:0008364)1.94909737
103Neoplasm of the rectum (HP:0100743)1.94188636
104Duplicated collecting system (HP:0000081)1.93563579
105Spastic diplegia (HP:0001264)1.91236708
106Overlapping toe (HP:0001845)1.91112072
107Pancreatic islet-cell hyperplasia (HP:0004510)1.90628997
108Ectopic kidney (HP:0000086)1.89932714
109Acute myeloid leukemia (HP:0004808)1.89338825
110Abnormality of the duodenum (HP:0002246)1.88390053
111Increased serum lactate (HP:0002151)1.86317464
112Lymphoma (HP:0002665)1.85693324
113Ankyloglossia (HP:0010296)1.85204066
114Secondary amenorrhea (HP:0000869)1.84737180
115Abnormal trabecular bone morphology (HP:0100671)1.84079948
116Reticulocytosis (HP:0001923)1.83657572
117Abnormality of the carotid arteries (HP:0005344)1.83106347
118Postnatal microcephaly (HP:0005484)1.82090649
119Deep philtrum (HP:0002002)1.81512937
120Abnormal lung lobation (HP:0002101)1.80770798
121Esophageal atresia (HP:0002032)1.80040581
122Gastrointestinal carcinoma (HP:0002672)1.79853889
123Malignant gastrointestinal tract tumors (HP:0006749)1.79853889
124Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.79775717
125Atrophy/Degeneration involving motor neurons (HP:0007373)1.78809424
126Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.78316103
127Abnormality of alanine metabolism (HP:0010916)1.78316103
128Hyperalaninemia (HP:0003348)1.78316103
129Short humerus (HP:0005792)1.77999944
130Triphalangeal thumb (HP:0001199)1.77963851
131Slender long bone (HP:0003100)1.77660622
132Septate vagina (HP:0001153)1.77394409
133Short thumb (HP:0009778)1.75722513
134Megaloblastic anemia (HP:0001889)1.75363652
135Clubbing of toes (HP:0100760)1.74572882
136Pancytopenia (HP:0001876)1.73991500
137Reduced antithrombin III activity (HP:0001976)1.72931153
138Abnormality of chromosome segregation (HP:0002916)1.69633612
139Abnormal glycosylation (HP:0012345)1.67817338
140Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67817338
141Abnormal protein N-linked glycosylation (HP:0012347)1.67817338
142Abnormal protein glycosylation (HP:0012346)1.67817338
143Short middle phalanx of the 5th finger (HP:0004220)1.67564191
144Abnormality of sulfur amino acid metabolism (HP:0004339)1.66486829
145Arteriovenous malformation (HP:0100026)1.65269250
146Embryonal neoplasm (HP:0002898)1.64115619
147Abnormality of the umbilical cord (HP:0010881)1.63509327
148Neoplasm of the adrenal gland (HP:0100631)1.61333549

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.51111720
2WEE14.19790231
3BUB13.96341172
4TSSK62.77260645
5EEF2K2.71280430
6PBK2.61566026
7EIF2AK12.60553712
8NEK22.51371933
9TTK2.36690933
10RPS6KB22.35662864
11NEK12.35035479
12CDK122.33049379
13VRK22.25208728
14SRPK12.10477939
15PASK2.08220745
16TLK12.06980766
17PKN21.95197286
18TESK21.93698354
19EPHA21.91279316
20CDK71.81450340
21MAP3K101.79372428
22PLK11.78956188
23MST41.78935525
24SCYL21.77703903
25ATR1.69424204
26SMG11.66825198
27NME21.65057576
28CDK41.63683433
29MAP3K81.63378718
30FLT31.61820717
31ACVR1B1.57926186
32STK101.55167748
33AURKB1.53627708
34EIF2AK31.53274784
35DYRK31.51007942
36MKNK11.44866698
37PLK41.39239399
38BRSK21.37712751
39TGFBR11.34941924
40PAK41.33909171
41TAF11.32605097
42PLK31.32260532
43CHEK11.31681929
44CHEK21.26084781
45ALK1.23780470
46VRK11.23751429
47AURKA1.21364675
48NME11.19374668
49RPS6KA41.15583957
50LRRK21.06086335
51EIF2AK21.05922875
52STK41.03373445
53MST1R1.00231806
54PNCK0.97896401
55PDK20.96056384
56CDK20.95023946
57BRD40.94682034
58ATM0.90984295
59PIM10.90466284
60MKNK20.90042659
61MAPKAPK30.89960570
62MAP4K10.86632897
63STK160.84787195
64TRIB30.82429796
65CDK60.81379355
66TRIM280.80791871
67CDK80.78946767
68CCNB10.78808725
69NUAK10.77929784
70BRSK10.77318775
71CSNK2A20.76081034
72ZAK0.74565267
73ERBB40.74213758
74BCKDK0.73768131
75MTOR0.73107026
76RAF10.69968424
77PAK10.68371546
78MAP2K30.66985761
79LATS10.65810757
80CDK10.62598384
81TTN0.60819474
82PRKCI0.60270303
83TESK10.59458051
84IRAK30.58514520
85CAMK1D0.56332458
86MAP3K110.54957702
87PAK20.54628100
88CSNK2A10.54525582
89CDK90.53945209
90CSNK1E0.53730677
91AKT20.52471849
92MAPKAPK50.52077274
93KDR0.51134133
94CAMK1G0.50156848
95MELK0.49456259
96GRK60.49177844
97FGFR10.47444322
98PIM20.43862781
99RPS6KA50.43798449
100BCR0.43782860
101CSNK1D0.42409179
102BTK0.42009185
103PRKDC0.41681453
104KSR20.34949786
105BMX0.34616645
106CLK10.34607728
107CDK30.34191185
108PDK40.33500045
109PDK30.33500045
110STK30.33248414
111LATS20.33171079
112MET0.32800730
113CSNK1G10.32313666
114MAP2K20.31814014
115CDK180.31406193
116PTK60.30398068
117PLK20.29993870
118ZAP700.29965614
119ICK0.29402354
120CSNK1G30.29107769
121CDK150.29038809
122CDK11A0.28972736
123CSNK1A1L0.28478858
124DAPK10.27529510
125MAPK140.27450340
126BRAF0.27420267
127BMPR1B0.27087764
128CDK140.26153164
129RPS6KA10.22676300
130MAPK10.22341839
131AKT10.21826796
132ILK0.21373990
133LIMK10.20224645
134RPS6KB10.19738106
135RPS6KC10.18205867

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.17936782
2Mismatch repair_Homo sapiens_hsa034304.54593254
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.78171437
4Spliceosome_Homo sapiens_hsa030403.38671893
5Ribosome_Homo sapiens_hsa030103.31898457
6RNA transport_Homo sapiens_hsa030133.28131290
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.01746252
8* One carbon pool by folate_Homo sapiens_hsa006702.98607132
9Base excision repair_Homo sapiens_hsa034102.95557560
10RNA polymerase_Homo sapiens_hsa030202.85212059
11Nucleotide excision repair_Homo sapiens_hsa034202.84504083
12Homologous recombination_Homo sapiens_hsa034402.78176227
13Cell cycle_Homo sapiens_hsa041102.59666115
14Proteasome_Homo sapiens_hsa030502.52792193
15Pyrimidine metabolism_Homo sapiens_hsa002402.25986796
16Fanconi anemia pathway_Homo sapiens_hsa034602.00058385
17Non-homologous end-joining_Homo sapiens_hsa034501.99608021
18mRNA surveillance pathway_Homo sapiens_hsa030151.81475632
19RNA degradation_Homo sapiens_hsa030181.76481164
20p53 signaling pathway_Homo sapiens_hsa041151.46614961
21Systemic lupus erythematosus_Homo sapiens_hsa053221.46193368
22Biosynthesis of amino acids_Homo sapiens_hsa012301.43294074
23Basal transcription factors_Homo sapiens_hsa030221.42978687
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.35962131
25Steroid biosynthesis_Homo sapiens_hsa001001.26987143
26Cyanoamino acid metabolism_Homo sapiens_hsa004601.24520682
27Selenocompound metabolism_Homo sapiens_hsa004501.23624599
28Cysteine and methionine metabolism_Homo sapiens_hsa002701.22135338
29Propanoate metabolism_Homo sapiens_hsa006401.18464248
30Viral carcinogenesis_Homo sapiens_hsa052031.12004759
31Epstein-Barr virus infection_Homo sapiens_hsa051691.10303345
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.06841005
33Pentose phosphate pathway_Homo sapiens_hsa000301.06030601
34Protein export_Homo sapiens_hsa030601.05948083
35* Purine metabolism_Homo sapiens_hsa002301.03264798
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.97413460
37Fatty acid elongation_Homo sapiens_hsa000620.94524252
38Antigen processing and presentation_Homo sapiens_hsa046120.92710789
39Carbon metabolism_Homo sapiens_hsa012000.90440617
40Drug metabolism - other enzymes_Homo sapiens_hsa009830.82526820
41Sulfur relay system_Homo sapiens_hsa041220.80210302
42Folate biosynthesis_Homo sapiens_hsa007900.79626650
43Herpes simplex infection_Homo sapiens_hsa051680.79204891
44Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.76891380
45Oocyte meiosis_Homo sapiens_hsa041140.76396779
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.73965723
47HTLV-I infection_Homo sapiens_hsa051660.73814349
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72489484
49Thyroid cancer_Homo sapiens_hsa052160.71724749
50Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.71475098
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.71421955
52Fatty acid metabolism_Homo sapiens_hsa012120.69664444
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.67254604
54MicroRNAs in cancer_Homo sapiens_hsa052060.67038730
55Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.66240038
56Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65436806
57Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.64652231
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.64322782
59Small cell lung cancer_Homo sapiens_hsa052220.61334157
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.58478832
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.54072632
62Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.51433539
63Legionellosis_Homo sapiens_hsa051340.50387649
64Glutathione metabolism_Homo sapiens_hsa004800.49618750
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48814870
66Parkinsons disease_Homo sapiens_hsa050120.48639771
67Alcoholism_Homo sapiens_hsa050340.48469742
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47927281
69Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46428812
70Hippo signaling pathway_Homo sapiens_hsa043900.45066116
71Basal cell carcinoma_Homo sapiens_hsa052170.44907608
72Notch signaling pathway_Homo sapiens_hsa043300.44597190
73Bladder cancer_Homo sapiens_hsa052190.44328768
74Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.43683177
75Fructose and mannose metabolism_Homo sapiens_hsa000510.43268481
76Lysine degradation_Homo sapiens_hsa003100.41564136
77Arginine biosynthesis_Homo sapiens_hsa002200.40599847
78Apoptosis_Homo sapiens_hsa042100.40455460
79Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40263759
80Colorectal cancer_Homo sapiens_hsa052100.39460438
81TGF-beta signaling pathway_Homo sapiens_hsa043500.38650330
82Chronic myeloid leukemia_Homo sapiens_hsa052200.38271101
83Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.36766906
84HIF-1 signaling pathway_Homo sapiens_hsa040660.34407465
85Galactose metabolism_Homo sapiens_hsa000520.32506237
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29273895
87Vitamin B6 metabolism_Homo sapiens_hsa007500.28920766
88mTOR signaling pathway_Homo sapiens_hsa041500.28842843
89Acute myeloid leukemia_Homo sapiens_hsa052210.27833467
90Primary immunodeficiency_Homo sapiens_hsa053400.27292024
91Arginine and proline metabolism_Homo sapiens_hsa003300.27192856
92Sulfur metabolism_Homo sapiens_hsa009200.26590345
93N-Glycan biosynthesis_Homo sapiens_hsa005100.26581073
94Oxidative phosphorylation_Homo sapiens_hsa001900.26550112
95Fatty acid biosynthesis_Homo sapiens_hsa000610.24164746
96Pathways in cancer_Homo sapiens_hsa052000.23313800
97Viral myocarditis_Homo sapiens_hsa054160.23276732
98Hepatitis B_Homo sapiens_hsa051610.22841866
99Pyruvate metabolism_Homo sapiens_hsa006200.20939791
100Adherens junction_Homo sapiens_hsa045200.20360863
101Butanoate metabolism_Homo sapiens_hsa006500.19983783
102Shigellosis_Homo sapiens_hsa051310.19181308
103Hedgehog signaling pathway_Homo sapiens_hsa043400.18752647
104Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.17782551
105Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.17618780
106Non-small cell lung cancer_Homo sapiens_hsa052230.14409637
107Measles_Homo sapiens_hsa051620.14284274
108Pancreatic cancer_Homo sapiens_hsa052120.14162146
109Tight junction_Homo sapiens_hsa045300.13528989
110Renin-angiotensin system_Homo sapiens_hsa046140.13365601
111* Metabolic pathways_Homo sapiens_hsa011000.12978456
112Prostate cancer_Homo sapiens_hsa052150.12806389
113NF-kappa B signaling pathway_Homo sapiens_hsa040640.12040282
114Vitamin digestion and absorption_Homo sapiens_hsa049770.11968649
115Huntingtons disease_Homo sapiens_hsa050160.10902205
116Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.10007599
117Pentose and glucuronate interconversions_Homo sapiens_hsa000400.09632622
118Wnt signaling pathway_Homo sapiens_hsa043100.09366478
119Proteoglycans in cancer_Homo sapiens_hsa052050.08120732
120Influenza A_Homo sapiens_hsa051640.07009059
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.06726684
122Fatty acid degradation_Homo sapiens_hsa000710.06299156
123Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.06002613

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