GAS2L3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1kinetochore organization (GO:0051383)4.84336177
2chromosome condensation (GO:0030261)4.42875589
3kinetochore assembly (GO:0051382)4.31919147
4regulation of sister chromatid cohesion (GO:0007063)4.20033858
5protein localization to kinetochore (GO:0034501)4.19412723
6mitotic cytokinesis (GO:0000281)4.05322081
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.04692057
8meiotic chromosome segregation (GO:0045132)3.94539359
9neutrophil activation involved in immune response (GO:0002283)3.92174718
10protein localization to chromosome, centromeric region (GO:0071459)3.84967832
11antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.83571374
12DNA packaging (GO:0006323)3.79761632
13ventricular cardiac muscle cell development (GO:0055015)3.73563241
14microtubule polymerization or depolymerization (GO:0031109)3.71873988
15regulation of centrosome cycle (GO:0046605)3.67003391
16CENP-A containing nucleosome assembly (GO:0034080)3.66604848
17mitotic metaphase plate congression (GO:0007080)3.63737266
18establishment of chromosome localization (GO:0051303)3.60086900
19membrane disassembly (GO:0030397)3.55924296
20positive regulation by symbiont of host defense response (GO:0052509)3.55713919
21modulation by symbiont of host defense response (GO:0052031)3.55713919
22modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.55713919
23modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.55713919
24positive regulation by organism of defense response of other organism involved in symbiotic interact3.55713919
25modulation by symbiont of host immune response (GO:0052553)3.55713919
26metaphase plate congression (GO:0051310)3.53585250
27mitotic spindle organization (GO:0007052)3.52349624
28resolution of meiotic recombination intermediates (GO:0000712)3.50291480
29establishment of mitotic spindle localization (GO:0040001)3.50224811
30sister chromatid segregation (GO:0000819)3.48864559
31chromatin remodeling at centromere (GO:0031055)3.48129649
32mitotic sister chromatid segregation (GO:0000070)3.46083084
33cytoskeleton-dependent cytokinesis (GO:0061640)3.40895587
34histone-serine phosphorylation (GO:0035404)3.40313383
35negative regulation of mitosis (GO:0045839)3.36201168
36definitive hemopoiesis (GO:0060216)3.35405038
37attachment of spindle microtubules to kinetochore (GO:0008608)3.33786092
38regulation of centrosome duplication (GO:0010824)3.30863595
39natural killer cell mediated cytotoxicity (GO:0042267)3.29249985
40natural killer cell mediated immunity (GO:0002228)3.29249985
41spindle assembly involved in mitosis (GO:0090307)3.27554859
42replication fork processing (GO:0031297)3.25257298
43centriole replication (GO:0007099)3.22384718
44positive regulation of mitotic sister chromatid separation (GO:1901970)3.21492852
45positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.21492852
46positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.21492852
47mitotic chromosome condensation (GO:0007076)3.21042261
48DNA unwinding involved in DNA replication (GO:0006268)3.19915101
49mitotic sister chromatid cohesion (GO:0007064)3.19161099
50mitotic G2/M transition checkpoint (GO:0044818)3.18549901
51regulation of exit from mitosis (GO:0007096)3.15207660
52mitotic nuclear division (GO:0007067)3.12859292
53maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.12017286
54DNA replication-independent nucleosome organization (GO:0034724)3.08291986
55DNA replication-independent nucleosome assembly (GO:0006336)3.08291986
56regulation of spindle organization (GO:0090224)3.06603051
57negative regulation of cell division (GO:0051782)3.05857681
58nuclear pore complex assembly (GO:0051292)3.03965154
59centrosome organization (GO:0051297)3.01357130
60regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.96569869
61mitotic cell cycle (GO:0000278)2.95367778
62negative regulation of DNA-dependent DNA replication (GO:2000104)2.95109556
63mitotic G2 DNA damage checkpoint (GO:0007095)2.94829152
64DNA topological change (GO:0006265)2.94746406
65microtubule anchoring (GO:0034453)2.93498478
66microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.93196592
67response to peptidoglycan (GO:0032494)2.92940103
68negative regulation of nuclear division (GO:0051784)2.91674105
69protein K6-linked ubiquitination (GO:0085020)2.91417096
70spindle checkpoint (GO:0031577)2.90085113
71mitotic recombination (GO:0006312)2.85515024
72non-recombinational repair (GO:0000726)2.85477143
73double-strand break repair via nonhomologous end joining (GO:0006303)2.85477143
74immunoglobulin mediated immune response (GO:0016064)2.84701655
75spindle organization (GO:0007051)2.84167382
76chromosome segregation (GO:0007059)2.82242925
77telomere maintenance via recombination (GO:0000722)2.81531515
78regulation of mitotic spindle organization (GO:0060236)2.81262890
79establishment of spindle localization (GO:0051293)2.80301614
80microtubule organizing center organization (GO:0031023)2.79883796
81nuclear pore organization (GO:0006999)2.79485594
82nuclear division (GO:0000280)2.78638837
83pore complex assembly (GO:0046931)2.77139188
84DNA double-strand break processing (GO:0000729)2.76893987
85mitotic cell cycle checkpoint (GO:0007093)2.76565713
86negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)2.75934006
87regulation of nuclear cell cycle DNA replication (GO:0033262)2.75546408
88histone exchange (GO:0043486)2.72819958
89neutrophil activation (GO:0042119)2.71730131
90positive regulation of gamma-delta T cell activation (GO:0046645)2.71029737
91regulation of DNA endoreduplication (GO:0032875)2.70965906
92negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.69684887
93microtubule depolymerization (GO:0007019)2.69549783
94positive regulation of chromosome segregation (GO:0051984)2.68153421
95B cell mediated immunity (GO:0019724)2.67968634
96regulation of mitotic metaphase/anaphase transition (GO:0030071)2.67124682
97G2/M transition of mitotic cell cycle (GO:0000086)2.65969103
98cell cycle G2/M phase transition (GO:0044839)2.65969103
99DNA ligation (GO:0006266)2.64433716
100neutrophil mediated immunity (GO:0002446)2.64397702
101melanin biosynthetic process (GO:0042438)2.63987901
102nuclear envelope organization (GO:0006998)2.63636256
103chromosome organization (GO:0051276)2.63422307
104negative regulation of phagocytosis (GO:0050765)2.63018541
105regulation of mitotic spindle checkpoint (GO:1903504)2.62856296
106regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.62856296
107regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.62736738
108telomere maintenance via semi-conservative replication (GO:0032201)2.61403582
109granulocyte activation (GO:0036230)2.60304097
110protein localization to chromosome (GO:0034502)2.57491106
111ribosomal small subunit assembly (GO:0000028)2.53918541
112regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.53810040
113spindle assembly checkpoint (GO:0071173)2.52665040
114mitotic nuclear envelope disassembly (GO:0007077)2.52571543
115regulation of sister chromatid segregation (GO:0033045)2.51191655
116regulation of mitotic sister chromatid separation (GO:0010965)2.51191655
117regulation of mitotic sister chromatid segregation (GO:0033047)2.51191655
118regulation of chromosome segregation (GO:0051983)2.50998063
119positive regulation of interleukin-1 beta secretion (GO:0050718)2.49804167
120positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.48065904
121superoxide anion generation (GO:0042554)2.47951680
122DNA replication initiation (GO:0006270)2.47076665
123regulation of centriole replication (GO:0046599)2.47006442
124myeloid dendritic cell activation (GO:0001773)2.44414914
125pinocytosis (GO:0006907)2.44068424
126mitotic spindle checkpoint (GO:0071174)2.41803611
127interkinetic nuclear migration (GO:0022027)2.41099633
128macrophage activation involved in immune response (GO:0002281)2.40992125
129negative regulation of mitotic sister chromatid separation (GO:2000816)2.40548778
130negative regulation of mitotic sister chromatid segregation (GO:0033048)2.40548778
131negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.40548778
132negative regulation of sister chromatid segregation (GO:0033046)2.40548778
133negative regulation of chromosome segregation (GO:0051985)2.39993867
134positive regulation of interferon-alpha production (GO:0032727)2.39839179
135respiratory burst (GO:0045730)2.38088122
136regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.37626284
137DNA strand elongation involved in DNA replication (GO:0006271)2.36541833
138negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.35651907
139chromatin assembly or disassembly (GO:0006333)2.33993069
140mitotic spindle assembly checkpoint (GO:0007094)2.31556911
141DNA strand elongation (GO:0022616)2.31352148
142response to muramyl dipeptide (GO:0032495)2.31024786
143nuclear envelope disassembly (GO:0051081)2.30040948

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.23231596
2* FOXM1_23109430_ChIP-Seq_U2OS_Human6.54447437
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.29126023
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.80550043
5IRF8_21731497_ChIP-ChIP_J774_Mouse3.58490132
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.45213265
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.15168604
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.87686742
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.52372409
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.39415917
11* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.38421893
12* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.34434490
13IRF8_27001747_Chip-Seq_BMDM_Mouse2.27859376
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.27142052
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.16427991
16E2F1_21310950_ChIP-Seq_MCF-7_Human2.09025202
17SCL_19346495_ChIP-Seq_HPC-7_Human2.08344498
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.06503519
19* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.01503745
20POU3F2_20337985_ChIP-ChIP_501MEL_Human1.97791591
21Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.94222330
22FUS_26573619_Chip-Seq_HEK293_Human1.91347605
23SPI1_23547873_ChIP-Seq_NB4_Human1.90595284
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.90062754
25ELK1_19687146_ChIP-ChIP_HELA_Human1.89381942
26FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.88719006
27CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.86741250
28MYC_18555785_ChIP-Seq_MESCs_Mouse1.82572402
29STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.80635545
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.78595118
31STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.77175189
32KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.76468471
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.72162094
34AR_21909140_ChIP-Seq_LNCAP_Human1.71971677
35HOXB4_20404135_ChIP-ChIP_EML_Mouse1.70570228
36TP63_19390658_ChIP-ChIP_HaCaT_Human1.67493442
37WT1_19549856_ChIP-ChIP_CCG9911_Human1.59588119
38TAF15_26573619_Chip-Seq_HEK293_Human1.56985587
39IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.47661133
40STAT4_19710469_ChIP-ChIP_TH1__Mouse1.46991635
41SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.46465327
42ELF1_17652178_ChIP-ChIP_JURKAT_Human1.44639986
43KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.44060576
44SALL1_21062744_ChIP-ChIP_HESCs_Human1.43275600
45NELFA_20434984_ChIP-Seq_ESCs_Mouse1.39644451
46* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39274560
47GBX2_23144817_ChIP-Seq_PC3_Human1.39169773
48MYC_19030024_ChIP-ChIP_MESCs_Mouse1.38426989
49BRD4_27068464_Chip-Seq_AML-cells_Mouse1.35947148
50HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.35140725
51PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.34243526
52P300_19829295_ChIP-Seq_ESCs_Human1.31610482
53ZNF274_21170338_ChIP-Seq_K562_Hela1.31311180
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.31299639
55EST1_17652178_ChIP-ChIP_JURKAT_Human1.31296388
56SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.31017785
57PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30965026
58VDR_22108803_ChIP-Seq_LS180_Human1.30574165
59VDR_23849224_ChIP-Seq_CD4+_Human1.27046493
60* PU_27001747_Chip-Seq_BMDM_Mouse1.26601092
61ZFP57_27257070_Chip-Seq_ESCs_Mouse1.25909084
62FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.24489315
63* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.24180231
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23419380
65MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.22284519
66TFEB_21752829_ChIP-Seq_HELA_Human1.21573129
67FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.18418035
68RUNX1_22412390_ChIP-Seq_EML_Mouse1.16808252
69MYC_18940864_ChIP-ChIP_HL60_Human1.16806744
70IGF1R_20145208_ChIP-Seq_DFB_Human1.16666945
71MYB_26560356_Chip-Seq_TH2_Human1.16217866
72TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.14872654
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14756204
74ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.14569974
75SOX9_26525672_Chip-Seq_HEART_Mouse1.14487028
76* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14201138
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12888045
78MYC_19079543_ChIP-ChIP_MESCs_Mouse1.12343694
79NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.11158334
80MYB_26560356_Chip-Seq_TH1_Human1.10784593
81FOXP3_21729870_ChIP-Seq_TREG_Human1.10057431
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07639736
83GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.07515048
84SOX2_16153702_ChIP-ChIP_HESCs_Human1.06860132
85VDR_24763502_ChIP-Seq_THP-1_Human1.04965487
86CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.04528345
87FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.03188468
88SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.02911422
89RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.02513439
90VDR_21846776_ChIP-Seq_THP-1_Human1.02200829
91CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01550255
92GATA2_22383799_ChIP-Seq_G1ME_Mouse1.01210043
93SOX17_20123909_ChIP-Seq_XEN_Mouse0.99251577
94CREB1_15753290_ChIP-ChIP_HEK293T_Human0.98112881
95MYCN_18555785_ChIP-Seq_MESCs_Mouse0.97636259
96OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97365934
97RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96941645
98NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.96919451
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.96522485
100SMAD3_21741376_ChIP-Seq_EPCs_Human0.95988657
101* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.95091699
102BRD4_25478319_ChIP-Seq_HGPS_Human0.94980905
103MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.94180797
104MYC_18358816_ChIP-ChIP_MESCs_Mouse0.92838085
105RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.92390632
106NANOG_18555785_ChIP-Seq_MESCs_Mouse0.91456376
107DCP1A_22483619_ChIP-Seq_HELA_Human0.90757719
108ETS1_20019798_ChIP-Seq_JURKAT_Human0.90137562
109PIAS1_25552417_ChIP-Seq_VCAP_Human0.89968022
110CTBP1_25329375_ChIP-Seq_LNCAP_Human0.89094338
111GATA1_22025678_ChIP-Seq_K562_Human0.88490550
112YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.88005554
113CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.87767703
114* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.87464680
115STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.87406000
116GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.87309391
117UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86417967
118E2F1_18555785_ChIP-Seq_MESCs_Mouse0.85842995
119THAP11_20581084_ChIP-Seq_MESCs_Mouse0.85669848
120GATA2_21666600_ChIP-Seq_HMVEC_Human0.85423572
121NANOG_16153702_ChIP-ChIP_HESCs_Human0.85138378
122EWS_26573619_Chip-Seq_HEK293_Human0.84181756
123SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.84063385
124SPI1_23127762_ChIP-Seq_K562_Human0.83679542
125* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.83673593
126* EZH2_27294783_Chip-Seq_NPCs_Mouse0.83673191
127NOTCH1_21737748_ChIP-Seq_TLL_Human0.82688583
128* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.82191660
129PADI4_21655091_ChIP-ChIP_MCF-7_Human0.81886887
130SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.81778707
131SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.81778707
132* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.81442869
133* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81303547
134SMAD4_21799915_ChIP-Seq_A2780_Human0.81033942
135RBPJ_22232070_ChIP-Seq_NCS_Mouse0.80964542
136GABP_17652178_ChIP-ChIP_JURKAT_Human0.80739967
137ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.80584370
138TTF2_22483619_ChIP-Seq_HELA_Human0.80262131
139SOX2_18555785_ChIP-Seq_MESCs_Mouse0.80036007
140CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.79804674
141* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.79456270
142PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.78526747
143STAT3_23295773_ChIP-Seq_U87_Human0.77883510
144CIITA_25753668_ChIP-Seq_RAJI_Human0.77378702
145NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.77094520
146HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.77086650
147MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.76981506
148TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.75869241
149* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.75717327
150POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.75519234
151SRF_21415370_ChIP-Seq_HL-1_Mouse0.74376624
152POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.73498065
153XRN2_22483619_ChIP-Seq_HELA_Human0.73158579
154NR3C1_21868756_ChIP-Seq_MCF10A_Human0.71823796
155IRF1_19129219_ChIP-ChIP_H3396_Human0.71405160
156NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.69601523

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.31202148
2MP0010094_abnormal_chromosome_stability3.04216609
3MP0003693_abnormal_embryo_hatching3.01089558
4MP0001835_abnormal_antigen_presentation2.76695416
5MP0005174_abnormal_tail_pigmentation2.72225705
6MP0003111_abnormal_nucleus_morphology2.69313288
7MP0003077_abnormal_cell_cycle2.45775289
8MP0002396_abnormal_hematopoietic_system2.37835047
9MP0003136_yellow_coat_color2.32563022
10MP0008057_abnormal_DNA_replication2.20553348
11MP0005248_abnormal_Harderian_gland2.20448333
12MP0008007_abnormal_cellular_replicative2.19784798
13MP0000015_abnormal_ear_pigmentation2.17720225
14MP0010307_abnormal_tumor_latency2.14408426
15MP0002419_abnormal_innate_immunity1.95711046
16MP0003436_decreased_susceptibility_to1.92462175
17MP0002095_abnormal_skin_pigmentation1.91206158
18MP0004808_abnormal_hematopoietic_stem1.83543320
19MP0002452_abnormal_antigen_presenting1.81951788
20MP0002148_abnormal_hypersensitivity_rea1.80334714
21MP0003718_maternal_effect1.77338161
22MP0009278_abnormal_bone_marrow1.76261311
23MP0003937_abnormal_limbs/digits/tail_de1.75457405
24MP0005397_hematopoietic_system_phenotyp1.74389713
25MP0001545_abnormal_hematopoietic_system1.74389713
26MP0005075_abnormal_melanosome_morpholog1.73615635
27MP0008058_abnormal_DNA_repair1.73239472
28MP0000372_irregular_coat_pigmentation1.70243695
29MP0009785_altered_susceptibility_to1.68484432
30MP0005171_absent_coat_pigmentation1.67611200
31MP0005000_abnormal_immune_tolerance1.67217866
32MP0005464_abnormal_platelet_physiology1.66618044
33MP0001800_abnormal_humoral_immune1.63471820
34MP0004957_abnormal_blastocyst_morpholog1.62631545
35MP0004381_abnormal_hair_follicle1.61979836
36MP0010030_abnormal_orbit_morphology1.60690006
37MP0002697_abnormal_eye_size1.58627440
38MP0000490_abnormal_crypts_of1.57994614
39MP0005408_hypopigmentation1.56707568
40MP0000647_abnormal_sebaceous_gland1.56561860
41MP0005025_abnormal_response_to1.54819072
42MP0002723_abnormal_immune_serum1.52877163
43MP0003950_abnormal_plasma_membrane1.52297593
44MP0001819_abnormal_immune_cell1.51363954
45MP0002420_abnormal_adaptive_immunity1.51143038
46MP0003890_abnormal_embryonic-extraembry1.50700761
47MP0000371_diluted_coat_color1.47874346
48MP0002006_tumorigenesis1.46659845
49MP0003448_altered_tumor_morphology1.43053525
50MP0002398_abnormal_bone_marrow1.40157021
51MP0010352_gastrointestinal_tract_polyps1.38799359
52MP0001286_abnormal_eye_development1.38319402
53MP0002092_abnormal_eye_morphology1.37561890
54MP0002233_abnormal_nose_morphology1.35396892
55MP0005671_abnormal_response_to1.35332320
56MP0008932_abnormal_embryonic_tissue1.33416291
57MP0003755_abnormal_palate_morphology1.30451733
58MP0005187_abnormal_penis_morphology1.29050477
59MP0005058_abnormal_lysosome_morphology1.28697583
60MP0000858_altered_metastatic_potential1.28613670
61MP0002075_abnormal_coat/hair_pigmentati1.28321881
62MP0002166_altered_tumor_susceptibility1.27246891
63MP0004510_myositis1.27032180
64MP0000689_abnormal_spleen_morphology1.26178775
65MP0005197_abnormal_uvea_morphology1.25909931
66MP0001853_heart_inflammation1.25006438
67MP0005257_abnormal_intraocular_pressure1.24455050
68MP0002405_respiratory_system_inflammati1.24082992
69MP0001324_abnormal_eye_pigmentation1.23284295
70MP0002102_abnormal_ear_morphology1.22776551
71MP0000716_abnormal_immune_system1.21390650
72MP0003303_peritoneal_inflammation1.20974773
73MP0001529_abnormal_vocalization1.19382824
74MP0002084_abnormal_developmental_patter1.18873822
75MP0002234_abnormal_pharynx_morphology1.17734004
76MP0001697_abnormal_embryo_size1.17387602
77MP0001790_abnormal_immune_system1.17224436
78MP0005387_immune_system_phenotype1.17224436
79MP0002722_abnormal_immune_system1.16947736
80MP0005391_vision/eye_phenotype1.16500362
81MP0002085_abnormal_embryonic_tissue1.15452708
82MP0009333_abnormal_splenocyte_physiolog1.15147057
83MP0003763_abnormal_thymus_physiology1.13622260
84MP0001186_pigmentation_phenotype1.12753200
85MP0005380_embryogenesis_phenotype1.12397564
86MP0000778_abnormal_nervous_system1.12021669
87MP0010678_abnormal_skin_adnexa1.11255432
88MP0006082_CNS_inflammation1.10230587
89MP0002429_abnormal_blood_cell1.09240670
90MP0005076_abnormal_cell_differentiation1.08438851
91MP0000427_abnormal_hair_cycle1.08167761
92MP0000350_abnormal_cell_proliferation1.07206369
93MP0000383_abnormal_hair_follicle1.07090316
94MP0010155_abnormal_intestine_physiology1.06456316
95MP0000537_abnormal_urethra_morphology1.05839019
96MP0002938_white_spotting1.05640828
97MP0003385_abnormal_body_wall1.02512025
98MP0003935_abnormal_craniofacial_develop1.02173823
99MP0003172_abnormal_lysosome_physiology1.01971674
100MP0000703_abnormal_thymus_morphology1.01084138
101MP0001915_intracranial_hemorrhage1.00657171
102MP0000465_gastrointestinal_hemorrhage1.00503124
103MP0002111_abnormal_tail_morphology0.99803469
104MP0002019_abnormal_tumor_incidence0.99796743
105MP0000685_abnormal_immune_system0.99541465
106MP0005253_abnormal_eye_physiology0.98912756
107MP0002877_abnormal_melanocyte_morpholog0.97602561
108MP0008260_abnormal_autophagy0.97578955
109MP0001929_abnormal_gametogenesis0.97255855
110MP0002090_abnormal_vision0.96913882
111MP0001299_abnormal_eye_distance/0.96485024
112MP0002277_abnormal_respiratory_mucosa0.96438486
113MP0002177_abnormal_outer_ear0.96088419
114MP0003566_abnormal_cell_adhesion0.94852246
115MP0008789_abnormal_olfactory_epithelium0.94850303
116MP0000313_abnormal_cell_death0.94720104
117MP0004947_skin_inflammation0.92842015
118MP0006292_abnormal_olfactory_placode0.92419635
119MP0003786_premature_aging0.92162881
120MP0004197_abnormal_fetal_growth/weight/0.92010345
121MP0003984_embryonic_growth_retardation0.91655714
122MP0000432_abnormal_head_morphology0.91199948
123MP0002210_abnormal_sex_determination0.89597695
124MP0000428_abnormal_craniofacial_morphol0.89536994
125MP0003861_abnormal_nervous_system0.89316331
126MP0002088_abnormal_embryonic_growth/wei0.89281991
127MP0003567_abnormal_fetal_cardiomyocyte0.89236409
128MP0006054_spinal_hemorrhage0.89093015
129MP0000358_abnormal_cell_content/0.89034992
130MP0002638_abnormal_pupillary_reflex0.88489975
131MP0006072_abnormal_retinal_apoptosis0.88478435
132MP0001845_abnormal_inflammatory_respons0.88471429
133MP0002009_preneoplasia0.88206177
134MP0009053_abnormal_anal_canal0.88048789
135MP0000049_abnormal_middle_ear0.86687512
136MP0002080_prenatal_lethality0.85029829
137MP0008877_abnormal_DNA_methylation0.84946405
138MP0002751_abnormal_autonomic_nervous0.81348855
139MP0003315_abnormal_perineum_morphology0.81309311
140MP0001730_embryonic_growth_arrest0.80629745
141MP0003943_abnormal_hepatobiliary_system0.80381040
142MP0003724_increased_susceptibility_to0.80280058
143MP0001533_abnormal_skeleton_physiology0.77373178
144MP0003119_abnormal_digestive_system0.76637848
145MP0001293_anophthalmia0.75747879
146MP0004272_abnormal_basement_membrane0.75638657
147MP0001346_abnormal_lacrimal_gland0.75385646
148MP0009697_abnormal_copulation0.74964991
149MP0002098_abnormal_vibrissa_morphology0.74611408
150MP0001119_abnormal_female_reproductive0.74035696
151MP0003787_abnormal_imprinting0.73491650
152MP0003453_abnormal_keratinocyte_physiol0.73370120
153MP0000767_abnormal_smooth_muscle0.72370559
154MP0001145_abnormal_male_reproductive0.71989938
155MP0003941_abnormal_skin_development0.71859844
156MP0001672_abnormal_embryogenesis/_devel0.70956873
157MP0009703_decreased_birth_body0.70920680
158MP0005195_abnormal_posterior_eye0.70649885
159MP0000653_abnormal_sex_gland0.69755389
160MP0002282_abnormal_trachea_morphology0.66373267
161MP0005395_other_phenotype0.64650869
162MP0002109_abnormal_limb_morphology0.64106168
163MP0002086_abnormal_extraembryonic_tissu0.63657691
164MP0000516_abnormal_urinary_system0.63634445

Predicted human phenotypes

RankGene SetZ-score
1Cortical dysplasia (HP:0002539)4.80357130
2Recurrent abscess formation (HP:0002722)4.70907227
3Chromsome breakage (HP:0040012)4.65928348
4Ulnar claw (HP:0001178)4.59825926
5Chromosomal breakage induced by crosslinking agents (HP:0003221)4.56792741
6Recurrent bacterial skin infections (HP:0005406)4.25842322
7Segmental peripheral demyelination/remyelination (HP:0003481)4.06815791
8Increased nuchal translucency (HP:0010880)3.54899579
9Abnormal lung lobation (HP:0002101)3.48890702
10Prostate neoplasm (HP:0100787)3.44643257
11Impaired proprioception (HP:0010831)3.42259034
12Eczematoid dermatitis (HP:0000976)3.11941950
13Abnormality of chromosome stability (HP:0003220)3.09666035
14Periodontitis (HP:0000704)2.95949451
15Agnosia (HP:0010524)2.88436549
16Myositis (HP:0100614)2.88249830
17Mediastinal lymphadenopathy (HP:0100721)2.82868373
18Embryonal renal neoplasm (HP:0011794)2.80608788
19Chronic obstructive pulmonary disease (HP:0006510)2.80302477
20Obstructive lung disease (HP:0006536)2.80302477
21Optic neuritis (HP:0100653)2.76894153
22Retrobulbar optic neuritis (HP:0100654)2.76894153
23Gingivitis (HP:0000230)2.74923691
24Hypopigmentation of the fundus (HP:0007894)2.74629240
25Abnormal auditory evoked potentials (HP:0006958)2.70965523
26Meckel diverticulum (HP:0002245)2.68789020
27Myelodysplasia (HP:0002863)2.64192483
28Ectopic kidney (HP:0000086)2.64175208
29Long clavicles (HP:0000890)2.61649248
30Aplasia/Hypoplasia of the fovea (HP:0008060)2.60742965
31Hypoplasia of the fovea (HP:0007750)2.60742965
32Clubbing of toes (HP:0100760)2.58682096
33Abnormality of the prostate (HP:0008775)2.57516897
34Aplasia/Hypoplasia of the uvula (HP:0010293)2.57466702
35Abnormality of macrophages (HP:0004311)2.57383157
36Abnormality of the preputium (HP:0100587)2.53565660
37Upper limb muscle weakness (HP:0003484)2.52768066
38Abnormality of the ileum (HP:0001549)2.52708144
39Reticulocytopenia (HP:0001896)2.51683994
40Absent frontal sinuses (HP:0002688)2.42567414
41Volvulus (HP:0002580)2.42345080
42Elevated erythrocyte sedimentation rate (HP:0003565)2.42337882
43Orchitis (HP:0100796)2.39639574
44Spinal cord lesions (HP:0100561)2.36132601
45Syringomyelia (HP:0003396)2.36132601
46Disinhibition (HP:0000734)2.31642566
47Abnormality of the fovea (HP:0000493)2.31424423
48Recurrent gram-negative bacterial infections (HP:0005420)2.30378548
49Acute myeloid leukemia (HP:0004808)2.29504149
50Small intestinal stenosis (HP:0012848)2.29449969
51Duodenal stenosis (HP:0100867)2.29449969
52Thrombocytosis (HP:0001894)2.26753145
53Thyroiditis (HP:0100646)2.26522155
54Abnormality of the renal collecting system (HP:0004742)2.26296567
55Duplicated collecting system (HP:0000081)2.26067158
56Increased CSF protein (HP:0002922)2.24213165
57Recurrent skin infections (HP:0001581)2.21045293
58Cellulitis (HP:0100658)2.19812736
59Thick nail (HP:0001805)2.19624416
60Recurrent fungal infections (HP:0002841)2.19353275
61Autoimmune thrombocytopenia (HP:0001973)2.12930161
62Prolonged bleeding time (HP:0003010)2.12747822
63Osteolytic defects of the hand bones (HP:0009699)2.12064386
64Osteolytic defects of the phalanges of the hand (HP:0009771)2.12064386
65Abnormality of the fingertips (HP:0001211)2.11297864
66Abnormality of the columella (HP:0009929)2.09074657
67Bone marrow hypocellularity (HP:0005528)2.08875357
68Osteomyelitis (HP:0002754)2.08744427
69Recurrent viral infections (HP:0004429)2.07807231
70Facial hemangioma (HP:0000329)2.07612171
71Intestinal atresia (HP:0011100)2.05560264
72Astigmatism (HP:0000483)2.04831339
73Leukocytosis (HP:0001974)2.04381507
74Absent radius (HP:0003974)2.04338722
75Aplasia/Hypoplasia of the sternum (HP:0006714)2.03043536
76High anterior hairline (HP:0009890)2.01329442
77Petechiae (HP:0000967)2.00024469
78Birth length less than 3rd percentile (HP:0003561)1.99817052
79Hypoplastic pelvis (HP:0008839)1.99070115
80Stomatitis (HP:0010280)1.98849910
81Deep philtrum (HP:0002002)1.98649870
82Rhabdomyosarcoma (HP:0002859)1.98459669
83Missing ribs (HP:0000921)1.94854703
84Meningitis (HP:0001287)1.94482634
85Aplasia/Hypoplasia of the macula (HP:0008059)1.94315361
86Cafe-au-lait spot (HP:0000957)1.94192341
87Aplasia involving forearm bones (HP:0009822)1.94064043
88Absent forearm bone (HP:0003953)1.94064043
89White forelock (HP:0002211)1.93548120
90Eosinophilia (HP:0001880)1.93448072
91Premature loss of primary teeth (HP:0006323)1.93128394
92Embryonal neoplasm (HP:0002898)1.92701301
93Abnormality of chromosome segregation (HP:0002916)1.92648441
94Arteriovenous malformation (HP:0100026)1.92034298
95Fibular hypoplasia (HP:0003038)1.91768176
96Keratoconjunctivitis sicca (HP:0001097)1.90685314
97Overlapping toe (HP:0001845)1.90507316
98Recurrent pneumonia (HP:0006532)1.89781986
99Triphalangeal thumb (HP:0001199)1.87470834
100Cutaneous melanoma (HP:0012056)1.87329674
101Short 4th metacarpal (HP:0010044)1.86793634
102Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.86793634
103Glioma (HP:0009733)1.85553077
104Patchy hypopigmentation of hair (HP:0011365)1.84930504
105Congenital sensorineural hearing impairment (HP:0008527)1.84199159
106Astrocytoma (HP:0009592)1.82048495
107Abnormality of the astrocytes (HP:0100707)1.82048495
108Dandy-Walker malformation (HP:0001305)1.81493414
109Oligodactyly (hands) (HP:0001180)1.81000048
110Submucous cleft hard palate (HP:0000176)1.80916722
11111 pairs of ribs (HP:0000878)1.80838023
112Bifid tongue (HP:0010297)1.80537919
113Blue irides (HP:0000635)1.80059458
114Impulsivity (HP:0100710)1.79664594
115Large earlobe (HP:0009748)1.78867136
116Cerebellar dysplasia (HP:0007033)1.78612201
117Granulocytopenia (HP:0001913)1.78302597
118Colon cancer (HP:0003003)1.78257936
119Aplasia/Hypoplasia of the fibula (HP:0006492)1.76897560
120Abnormality of the carotid arteries (HP:0005344)1.75990792
121Small hand (HP:0200055)1.75823093
122Abnormality of the duodenum (HP:0002246)1.75224845
123Aplasia/Hypoplasia affecting the retina (HP:0008061)1.74592943
124Neoplasm of the colon (HP:0100273)1.74570081
125Vertebral arch anomaly (HP:0008438)1.74363956
126Leukopenia (HP:0001882)1.74341793
127Nephroblastoma (Wilms tumor) (HP:0002667)1.74255933
128Lymphoma (HP:0002665)1.74122539
129Pustule (HP:0200039)1.74006125
130Arterial thrombosis (HP:0004420)1.73422851
131Preaxial hand polydactyly (HP:0001177)1.73219953
132Increased neuronal autofluorescent lipopigment (HP:0002074)1.71879285
133Abnormality of the nasal septum (HP:0000419)1.71275134
134Abnormality of the proximal phalanges of the hand (HP:0009834)1.71149334
135Short thumb (HP:0009778)1.69934051
136Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.69639679
137Keratoconjunctivitis (HP:0001096)1.69633434
138Peripheral demyelination (HP:0011096)1.69343375
139Abnormality of male internal genitalia (HP:0000022)1.69093254
140Sloping forehead (HP:0000340)1.67765558
141Hematochezia (HP:0002573)1.67618994
142Premature graying of hair (HP:0002216)1.66921454
143Facial cleft (HP:0002006)1.66913825
144Absent thumb (HP:0009777)1.66130754
145Supernumerary spleens (HP:0009799)1.65894716
146Vacuolated lymphocytes (HP:0001922)1.65484444
147Abnormality of the pleura (HP:0002103)1.64750430
148Vasculitis (HP:0002633)1.64672494
149Spinal muscular atrophy (HP:0007269)1.64652232
150Basal ganglia calcification (HP:0002135)1.64386595
151Papillary thyroid carcinoma (HP:0002895)1.62823608
152Abnormality of DNA repair (HP:0003254)1.62801614
153Bruising susceptibility (HP:0000978)1.62417596
154Leiomyosarcoma (HP:0100243)1.61793555
155Uterine leiomyosarcoma (HP:0002891)1.61793555
156Abnormality of the frontal sinuses (HP:0002687)1.60511773
157Increased cerebral lipofuscin (HP:0011813)1.60376548
158Abnormality of eosinophils (HP:0001879)1.60105160
159Aplasia/Hypoplasia of the tibia (HP:0005772)1.59888412
160Ependymoma (HP:0002888)1.59250991
161Proximal placement of thumb (HP:0009623)1.58953584
162Molar tooth sign on MRI (HP:0002419)1.57840412
163Abnormality of midbrain morphology (HP:0002418)1.57840412
164Hemivertebrae (HP:0002937)1.57115994
165Transitional cell carcinoma of the bladder (HP:0006740)1.56281535
166Deviation of the thumb (HP:0009603)1.56008501
167Cystic hygroma (HP:0000476)1.54636024
168Oligodactyly (HP:0012165)1.54062875
169Esophageal atresia (HP:0002032)1.53998936
170Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.53761466
171Vertebral hypoplasia (HP:0008417)1.53761466
172Freckling (HP:0001480)1.52764143
173Pancreatic cysts (HP:0001737)1.52663069
174Abnormality of the septum pellucidum (HP:0007375)1.52073114
175Median cleft lip (HP:0000161)1.51989875
176Synophrys (HP:0000664)1.51171908
177Choanal atresia (HP:0000453)1.50833317
178Patellar aplasia (HP:0006443)1.50529084
179Bladder neoplasm (HP:0009725)1.50149371
180Bladder carcinoma (HP:0002862)1.50149371

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK13.50355551
2MAP3K142.80873763
3CDC72.64004693
4WEE12.43018790
5IRAK32.38100819
6PLK42.29024685
7BUB12.26344653
8IRAK42.24614169
9PBK2.17682318
10ZAK2.13645660
11ACVR1B2.07067973
12NEK22.05158569
13CDK121.95603627
14PNCK1.95267278
15TXK1.88191649
16STK41.87624584
17MKNK11.86626981
18BLK1.86317847
19KIT1.84797206
20BRSK21.77312711
21PIM11.68666562
22TTK1.64867116
23MKNK21.58590327
24SRPK11.57730927
25RPS6KA41.54509134
26ATR1.50024889
27EIF2AK21.49768082
28IKBKB1.49216182
29PLK11.49121771
30AURKB1.43309681
31NME21.40349447
32TEC1.39923097
33NEK91.39516650
34CHUK1.37881146
35STK101.37247385
36BCR1.36447132
37STK31.35032333
38CDK61.34085647
39MAP4K11.31850706
40YES11.30961891
41TAOK31.30363026
42MET1.28573214
43TNIK1.26685350
44JAK31.25289328
45TSSK61.22804435
46TRIM281.22455106
47VRK11.21556988
48CHEK21.20223377
49CDK71.20114893
50TLK11.16896952
51PLK31.16273074
52NUAK11.16210561
53MARK31.11554766
54IKBKE1.11036360
55CLK11.10255160
56TBK11.08384461
57RIPK41.07923567
58TAF11.07235688
59BTK1.04508976
60ERBB41.03173896
61EPHB20.97951587
62CDK40.95636601
63LATS20.94980152
64MAP3K40.94357445
65MAP3K80.93979176
66MST1R0.92157897
67BRD40.91578139
68MELK0.91442469
69TYK20.91286960
70EIF2AK10.90750416
71TRPM70.90221412
72CSF1R0.90124303
73STK390.88346435
74PDK20.87383602
75ATM0.87264674
76LATS10.85963327
77LYN0.85358742
78TGFBR10.83844553
79INSRR0.80771589
80BRAF0.77372682
81ERBB30.76229030
82MST40.76207671
83CDK80.75387343
84WNK30.74530441
85CAMK1G0.73007993
86STK240.72243049
87BMPR1B0.71310053
88TGFBR20.70749275
89SYK0.70740028
90BRSK10.69322387
91LCK0.68760525
92FGFR10.66520190
93PIM20.65551344
94CCNB10.65079823
95HCK0.64931080
96EIF2AK30.63397604
97CDK10.62077155
98FRK0.61808464
99IRAK20.61778326
100CHEK10.61584000
101BMPR20.60782457
102BMX0.60454587
103AURKA0.60450240
104RPS6KA50.60097739
105RPS6KA60.60005037
106MAP2K70.58062948
107CASK0.57812258
108MATK0.57567022
109RPS6KB20.56384571
110SIK30.54980043
111RPS6KC10.53721274
112RPS6KL10.53721274
113KSR10.52201554
114CSNK1G10.51547526
115IRAK10.51334526
116CDK90.50902328
117PLK20.50099952
118FLT30.50035349
119STK38L0.49914725
120ZAP700.48917368
121UHMK10.48553998
122PAK40.47613210
123CDK20.46557690
124WNK40.46404588
125VRK20.46237874
126JAK10.45559420
127TIE10.44724320
128CAMK1D0.44552585
129EPHA20.44433271
130FGFR30.43951447
131CDK180.43558615
132CSNK1A1L0.40920687
133CDK30.39847859
134PAK20.39520272
135CDK150.37421159
136PAK60.37149136
137CSNK1G20.36842466
138SCYL20.34794600
139CDK11A0.32048580
140MAPK130.31686056
141CDK140.30579105
142CSNK1G30.29489067
143PDGFRA0.28869857
144AKT20.28518766
145PRKCI0.26931955
146MAP4K20.25830127
147MINK10.25731206

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.85150258
2Mismatch repair_Homo sapiens_hsa034302.47560027
3Homologous recombination_Homo sapiens_hsa034402.29920505
4Fanconi anemia pathway_Homo sapiens_hsa034602.25921973
5Base excision repair_Homo sapiens_hsa034102.23078962
6Cell cycle_Homo sapiens_hsa041102.18765995
7Oocyte meiosis_Homo sapiens_hsa041142.14896232
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.05993614
9Steroid biosynthesis_Homo sapiens_hsa001002.05311942
10Non-homologous end-joining_Homo sapiens_hsa034501.98221200
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.92529443
12NOD-like receptor signaling pathway_Homo sapiens_hsa046211.91704005
13Leishmaniasis_Homo sapiens_hsa051401.86097647
14Protein export_Homo sapiens_hsa030601.80103175
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.67657803
16p53 signaling pathway_Homo sapiens_hsa041151.65464086
17Measles_Homo sapiens_hsa051621.65193362
18Hippo signaling pathway_Homo sapiens_hsa043901.63077335
19One carbon pool by folate_Homo sapiens_hsa006701.62098822
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.61626898
21Nucleotide excision repair_Homo sapiens_hsa034201.57454847
22Toll-like receptor signaling pathway_Homo sapiens_hsa046201.55876491
23Herpes simplex infection_Homo sapiens_hsa051681.54184479
24Spliceosome_Homo sapiens_hsa030401.47681453
25Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.46920280
26Osteoclast differentiation_Homo sapiens_hsa043801.45603200
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.42623683
28Legionellosis_Homo sapiens_hsa051341.41671929
29RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.35752198
30RNA transport_Homo sapiens_hsa030131.35103904
31Systemic lupus erythematosus_Homo sapiens_hsa053221.35008012
32Hematopoietic cell lineage_Homo sapiens_hsa046401.34886859
33Small cell lung cancer_Homo sapiens_hsa052221.32209163
34Transcriptional misregulation in cancer_Homo sapiens_hsa052021.30897098
35Apoptosis_Homo sapiens_hsa042101.30104041
36Influenza A_Homo sapiens_hsa051641.27209509
37Graft-versus-host disease_Homo sapiens_hsa053321.26701828
38Allograft rejection_Homo sapiens_hsa053301.26047669
39Basal cell carcinoma_Homo sapiens_hsa052171.25767821
40Malaria_Homo sapiens_hsa051441.25746282
41B cell receptor signaling pathway_Homo sapiens_hsa046621.25233478
42TGF-beta signaling pathway_Homo sapiens_hsa043501.24322365
43MicroRNAs in cancer_Homo sapiens_hsa052061.23421169
44Basal transcription factors_Homo sapiens_hsa030221.21187630
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.20753391
46Asthma_Homo sapiens_hsa053101.19809846
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.19266801
48Selenocompound metabolism_Homo sapiens_hsa004501.17189465
49Hepatitis B_Homo sapiens_hsa051611.16028500
50RNA polymerase_Homo sapiens_hsa030201.15668698
51RNA degradation_Homo sapiens_hsa030181.14531999
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.14100540
53Cysteine and methionine metabolism_Homo sapiens_hsa002701.13660813
54Intestinal immune network for IgA production_Homo sapiens_hsa046721.13464439
55Tuberculosis_Homo sapiens_hsa051521.12301078
56Pertussis_Homo sapiens_hsa051331.11822656
57Viral carcinogenesis_Homo sapiens_hsa052031.11683785
58Propanoate metabolism_Homo sapiens_hsa006401.10978332
59Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.09971499
60Other glycan degradation_Homo sapiens_hsa005111.09647616
61Antigen processing and presentation_Homo sapiens_hsa046121.09261207
62Ribosome_Homo sapiens_hsa030101.08671280
63Pyrimidine metabolism_Homo sapiens_hsa002401.07795579
64Toxoplasmosis_Homo sapiens_hsa051451.06831256
65TNF signaling pathway_Homo sapiens_hsa046681.06356380
66Epstein-Barr virus infection_Homo sapiens_hsa051691.05175410
67Lysine degradation_Homo sapiens_hsa003101.03617524
68Shigellosis_Homo sapiens_hsa051311.03044405
69Hedgehog signaling pathway_Homo sapiens_hsa043401.02012808
70Chronic myeloid leukemia_Homo sapiens_hsa052201.01844923
71Primary immunodeficiency_Homo sapiens_hsa053401.00725651
72Phagosome_Homo sapiens_hsa041450.98139750
73Staphylococcus aureus infection_Homo sapiens_hsa051500.96403244
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.96366385
75Viral myocarditis_Homo sapiens_hsa054160.95837498
76Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.95250217
77Fatty acid elongation_Homo sapiens_hsa000620.94663737
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92753662
79Salmonella infection_Homo sapiens_hsa051320.91365512
80Glycosaminoglycan degradation_Homo sapiens_hsa005310.90258632
81Jak-STAT signaling pathway_Homo sapiens_hsa046300.87395650
82Pyruvate metabolism_Homo sapiens_hsa006200.86608515
83Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.85430880
84Acute myeloid leukemia_Homo sapiens_hsa052210.85062261
85Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.84687311
86Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.83067744
87Rheumatoid arthritis_Homo sapiens_hsa053230.80151996
88Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.79830438
89Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.79741505
90HTLV-I infection_Homo sapiens_hsa051660.79701014
91Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.79333650
92Biosynthesis of amino acids_Homo sapiens_hsa012300.78413668
93Lysosome_Homo sapiens_hsa041420.75457056
94mRNA surveillance pathway_Homo sapiens_hsa030150.75400530
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75173074
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73044139
97Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73039262
98Chemokine signaling pathway_Homo sapiens_hsa040620.72462438
99Leukocyte transendothelial migration_Homo sapiens_hsa046700.72213012
100Platelet activation_Homo sapiens_hsa046110.70955917
101Purine metabolism_Homo sapiens_hsa002300.70329124
102Pancreatic cancer_Homo sapiens_hsa052120.69595268
103Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69030246
104Hepatitis C_Homo sapiens_hsa051600.68412736
105AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.67243135
106Alcoholism_Homo sapiens_hsa050340.67184252
107African trypanosomiasis_Homo sapiens_hsa051430.66660085
108Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.65201506
109Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64164708
110Axon guidance_Homo sapiens_hsa043600.63643842
111Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.63077926
112Prostate cancer_Homo sapiens_hsa052150.63020450
113ECM-receptor interaction_Homo sapiens_hsa045120.62999585
114Tight junction_Homo sapiens_hsa045300.62368314
115Wnt signaling pathway_Homo sapiens_hsa043100.61003966
116Autoimmune thyroid disease_Homo sapiens_hsa053200.59911866
117Glutathione metabolism_Homo sapiens_hsa004800.59079212
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.57356078
119Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57325016
120Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57088845
121Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56260456
122Proteasome_Homo sapiens_hsa030500.55938843
123N-Glycan biosynthesis_Homo sapiens_hsa005100.55512197
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.55354480
125Butanoate metabolism_Homo sapiens_hsa006500.53520460
126Melanoma_Homo sapiens_hsa052180.53336125
127FoxO signaling pathway_Homo sapiens_hsa040680.53262969
128Fatty acid metabolism_Homo sapiens_hsa012120.51565698
129Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51230131
130Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50952759
131Adherens junction_Homo sapiens_hsa045200.48155766
132Colorectal cancer_Homo sapiens_hsa052100.48130071
133Amoebiasis_Homo sapiens_hsa051460.48088679
134Carbon metabolism_Homo sapiens_hsa012000.47902469
135T cell receptor signaling pathway_Homo sapiens_hsa046600.47671245
136Huntingtons disease_Homo sapiens_hsa050160.47665461
137Sphingolipid metabolism_Homo sapiens_hsa006000.47340930
138Prolactin signaling pathway_Homo sapiens_hsa049170.47044449
139Pathways in cancer_Homo sapiens_hsa052000.46275985
140Notch signaling pathway_Homo sapiens_hsa043300.44990288
141Thyroid cancer_Homo sapiens_hsa052160.43477660
142PI3K-Akt signaling pathway_Homo sapiens_hsa041510.41928102
143Melanogenesis_Homo sapiens_hsa049160.41301301
144Folate biosynthesis_Homo sapiens_hsa007900.37974013
145Fatty acid biosynthesis_Homo sapiens_hsa000610.36684069
146Nitrogen metabolism_Homo sapiens_hsa009100.36572666
147Metabolic pathways_Homo sapiens_hsa011000.33680092
148Proteoglycans in cancer_Homo sapiens_hsa052050.32543312
149Primary bile acid biosynthesis_Homo sapiens_hsa001200.32310661
150Gap junction_Homo sapiens_hsa045400.32066620
151Circadian rhythm_Homo sapiens_hsa047100.31240540
152Bladder cancer_Homo sapiens_hsa052190.31154877
1532-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.26992488
154Pentose phosphate pathway_Homo sapiens_hsa000300.26860474
155Central carbon metabolism in cancer_Homo sapiens_hsa052300.25276301
156Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.23649862
157Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.23004127
158Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.22195224
159Pentose and glucuronate interconversions_Homo sapiens_hsa000400.21730761
160Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.19958276
161Sulfur metabolism_Homo sapiens_hsa009200.19201897
162Oxidative phosphorylation_Homo sapiens_hsa001900.18534747

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