GAS7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.22143749
2sodium ion export (GO:0071436)5.20248462
3locomotory exploration behavior (GO:0035641)4.76439966
4vocalization behavior (GO:0071625)4.71658002
5regulation of short-term neuronal synaptic plasticity (GO:0048172)4.69813668
6synaptic vesicle maturation (GO:0016188)4.65856573
7axon ensheathment in central nervous system (GO:0032291)4.65143960
8central nervous system myelination (GO:0022010)4.65143960
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.63340198
10synaptic vesicle exocytosis (GO:0016079)4.58884980
11neuronal action potential propagation (GO:0019227)4.57156376
12ionotropic glutamate receptor signaling pathway (GO:0035235)4.51046679
13neuron cell-cell adhesion (GO:0007158)4.42713160
14protein localization to synapse (GO:0035418)4.30315194
15positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.18943589
16glutamate receptor signaling pathway (GO:0007215)4.11187197
17regulation of ARF protein signal transduction (GO:0032012)4.09396855
18dendritic spine morphogenesis (GO:0060997)4.07951361
19regulation of synaptic vesicle exocytosis (GO:2000300)4.06530788
20presynaptic membrane assembly (GO:0097105)4.06438900
21regulation of glutamate receptor signaling pathway (GO:1900449)4.05097089
22glutamate secretion (GO:0014047)4.00587140
23cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.99737994
24presynaptic membrane organization (GO:0097090)3.95645171
25synaptic transmission, glutamatergic (GO:0035249)3.91242629
26L-amino acid import (GO:0043092)3.82257766
27regulation of long-term neuronal synaptic plasticity (GO:0048169)3.79981803
28transmission of nerve impulse (GO:0019226)3.79090936
29neuron-neuron synaptic transmission (GO:0007270)3.76114380
30regulation of excitatory postsynaptic membrane potential (GO:0060079)3.73807052
31regulation of neuronal synaptic plasticity (GO:0048168)3.73044089
32positive regulation of membrane potential (GO:0045838)3.70351920
33exploration behavior (GO:0035640)3.68520820
34gamma-aminobutyric acid signaling pathway (GO:0007214)3.59559735
35cerebellar granule cell differentiation (GO:0021707)3.59454550
36regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.58931618
37long-chain fatty acid biosynthetic process (GO:0042759)3.57960971
38potassium ion import (GO:0010107)3.53051100
39gamma-aminobutyric acid transport (GO:0015812)3.52272698
40long-term memory (GO:0007616)3.50885815
41potassium ion homeostasis (GO:0055075)3.50696968
42regulation of dendritic spine morphogenesis (GO:0061001)3.50324353
43regulation of synaptic vesicle transport (GO:1902803)3.48227687
44neurotransmitter-gated ion channel clustering (GO:0072578)3.47387830
45regulation of postsynaptic membrane potential (GO:0060078)3.47070086
46negative regulation of neurotransmitter transport (GO:0051589)3.46931574
47myelination (GO:0042552)3.43230277
48ensheathment of neurons (GO:0007272)3.41773100
49axon ensheathment (GO:0008366)3.41773100
50neuron recognition (GO:0008038)3.34657265
51negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.34631642
52neuromuscular process controlling posture (GO:0050884)3.34598104
53regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.32258559
54synaptic vesicle docking involved in exocytosis (GO:0016081)3.31528650
55layer formation in cerebral cortex (GO:0021819)3.30744133
56regulation of synapse structural plasticity (GO:0051823)3.29424874
57negative regulation of synaptic transmission, GABAergic (GO:0032229)3.28256842
58cell communication by electrical coupling (GO:0010644)3.27788723
59long-term synaptic potentiation (GO:0060291)3.27015996
60regulation of dendritic spine development (GO:0060998)3.23802819
61neurotransmitter secretion (GO:0007269)3.23459797
62regulation of synaptic plasticity (GO:0048167)3.23439102
63adult walking behavior (GO:0007628)3.22617157
64proline transport (GO:0015824)3.21180628
65negative regulation of neurotransmitter secretion (GO:0046929)3.21106282
66regulation of voltage-gated calcium channel activity (GO:1901385)3.18294205
67G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.17241552
68neuronal ion channel clustering (GO:0045161)3.17179498
69membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.16634219
70cytoskeletal anchoring at plasma membrane (GO:0007016)3.15953636
71regulation of neurotransmitter levels (GO:0001505)3.13769688
72positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.13123546
73regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.10134982
74postsynaptic membrane organization (GO:0001941)3.09093361
75dendritic spine organization (GO:0097061)3.05793295
76axonal fasciculation (GO:0007413)3.04241963
77regulation of synapse maturation (GO:0090128)3.03722988
78cellular sodium ion homeostasis (GO:0006883)3.03713268
79regulation of synaptic transmission, glutamatergic (GO:0051966)3.02188796
80positive regulation of dendritic spine development (GO:0060999)3.01241876
81G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.00616094
82negative regulation of dendrite morphogenesis (GO:0050774)3.00191806
83regulation of glutamate secretion (GO:0014048)2.97326882
84synaptic vesicle endocytosis (GO:0048488)2.95810294
85regulation of neurotransmitter secretion (GO:0046928)2.95591927
86dendrite morphogenesis (GO:0048813)2.95513817
87neuromuscular process controlling balance (GO:0050885)2.95443269
88positive regulation of neurotransmitter transport (GO:0051590)2.95382415
89positive regulation of Rap GTPase activity (GO:0032854)2.94015473
90negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.93581095
91membrane hyperpolarization (GO:0060081)2.90836816
92negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.90598407
93membrane depolarization (GO:0051899)2.90427490
94positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.90290190
95amino acid import (GO:0043090)2.86932458
96cellular potassium ion homeostasis (GO:0030007)2.85533995
97learning (GO:0007612)2.84281531
98activation of protein kinase A activity (GO:0034199)2.84071046
99behavioral response to cocaine (GO:0048148)2.83347086
100negative regulation of amino acid transport (GO:0051956)2.82240185
101neurotransmitter transport (GO:0006836)2.82220878
102fatty acid elongation (GO:0030497)2.81772607
103regulation of vesicle fusion (GO:0031338)2.78133422
104acidic amino acid transport (GO:0015800)2.77640149
105negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.76591175
106regulation of exocytosis (GO:0017157)2.76123441
107auditory behavior (GO:0031223)2.74182629
108long term synaptic depression (GO:0060292)2.73962320
109response to histamine (GO:0034776)2.72774891
110regulation of neurotransmitter transport (GO:0051588)2.71604052
111regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.70907493
112regulation of Rap GTPase activity (GO:0032317)2.70216396
113membrane depolarization during action potential (GO:0086010)2.68899404
114neurotransmitter uptake (GO:0001504)2.68816479
115positive regulation of neurotransmitter secretion (GO:0001956)2.68507488
116synapse assembly (GO:0007416)2.68339874
117nerve growth factor signaling pathway (GO:0038180)2.67895810
118regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.66843610
119positive regulation of synapse maturation (GO:0090129)2.66236523
120negative regulation of axonogenesis (GO:0050771)2.65887591
121chemosensory behavior (GO:0007635)2.65112315
122vesicle docking involved in exocytosis (GO:0006904)2.64992847
123regulation of synaptic transmission (GO:0050804)2.64478160
124negative regulation of protein localization to cell surface (GO:2000009)2.63574867
125cerebellar Purkinje cell differentiation (GO:0021702)2.63031526
126synapse organization (GO:0050808)2.62946847
127mating behavior (GO:0007617)2.62480521
128glycine transport (GO:0015816)2.60092603
129macrophage activation involved in immune response (GO:0002281)2.58049787
130signal complex assembly (GO:0007172)2.56625338
131regulation of regulated secretory pathway (GO:1903305)2.56451703
132negative regulation of erythrocyte differentiation (GO:0045647)2.53781952
133neuromuscular process (GO:0050905)2.53567126
134regulation of beta-amyloid formation (GO:1902003)2.52754700
135cell differentiation in hindbrain (GO:0021533)2.52406934
136positive regulation of macrophage cytokine production (GO:0060907)2.47440807
137positive regulation of cellular amide metabolic process (GO:0034250)2.47215567
138establishment of synaptic vesicle localization (GO:0097480)2.47138364
139synaptic vesicle transport (GO:0048489)2.47138364

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.07103032
2GBX2_23144817_ChIP-Seq_PC3_Human3.55688495
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.04612899
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02406608
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.95722828
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.88705491
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.62886375
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.62886375
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55173321
10MTF2_20144788_ChIP-Seq_MESCs_Mouse2.48339576
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.45359065
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.43945521
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.43405946
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.40875953
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.40155354
16* DROSHA_22980978_ChIP-Seq_HELA_Human2.35543858
17* RARB_27405468_Chip-Seq_BRAIN_Mouse2.23420992
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.22295548
19REST_21632747_ChIP-Seq_MESCs_Mouse2.20975485
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.19167922
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.17810762
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.11767851
23AR_21572438_ChIP-Seq_LNCaP_Human2.03339702
24KDM2B_26808549_Chip-Seq_SUP-B15_Human2.00807027
25KDM2B_26808549_Chip-Seq_K562_Human1.89613282
26BP1_19119308_ChIP-ChIP_Hs578T_Human1.88971023
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.83593954
28TAF15_26573619_Chip-Seq_HEK293_Human1.80733450
29REST_18959480_ChIP-ChIP_MESCs_Mouse1.74396849
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.66864061
31MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.65012508
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.64412709
33* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64087906
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.61798335
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.61414375
36LXR_22292898_ChIP-Seq_THP-1_Human1.60302062
37ZFP281_18757296_ChIP-ChIP_E14_Mouse1.54948060
38SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.52830747
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.52055037
40SMAD4_21799915_ChIP-Seq_A2780_Human1.51634167
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.49675061
42GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.49149396
43SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.48500880
44KDM2B_26808549_Chip-Seq_DND41_Human1.46331313
45* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45458071
46EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.44570295
47CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42746301
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41129998
49PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.40789605
50P300_19829295_ChIP-Seq_ESCs_Human1.40299947
51* SMAD3_21741376_ChIP-Seq_EPCs_Human1.39999812
52* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39202527
53ESR2_21235772_ChIP-Seq_MCF-7_Human1.39147333
54* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.37693481
55* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36806967
56RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.35718717
57STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.34001622
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.32380549
59NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.29869927
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29687793
61EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28554381
62PIAS1_25552417_ChIP-Seq_VCAP_Human1.27109019
63* IRF8_27001747_Chip-Seq_BMDM_Mouse1.26831281
64ERG_21242973_ChIP-ChIP_JURKAT_Human1.26643593
65GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.26414862
66ZFP281_27345836_Chip-Seq_ESCs_Mouse1.26196496
67SPI1_23127762_ChIP-Seq_K562_Human1.25635951
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.23738714
69CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.21373728
70SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.21348392
71POU3F2_20337985_ChIP-ChIP_501MEL_Human1.20919323
72ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19419273
73NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.19283320
74TCF7_22412390_ChIP-Seq_EML_Mouse1.18987056
75STAT3_23295773_ChIP-Seq_U87_Human1.18658142
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17912429
77* GATA1_19941827_ChIP-Seq_MEL_Mouse1.17586253
78SMAD_19615063_ChIP-ChIP_OVARY_Human1.17508385
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17112678
80ER_23166858_ChIP-Seq_MCF-7_Human1.16565397
81* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15425369
82SOX2_21211035_ChIP-Seq_LN229_Gbm1.15247608
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.14932562
84* TP53_16413492_ChIP-PET_HCT116_Human1.12291600
85RING1B_27294783_Chip-Seq_ESCs_Mouse1.11905542
86AR_25329375_ChIP-Seq_VCAP_Human1.11125055
87Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.11076792
88BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11057963
89NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10813079
90SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10441199
91ARNT_22903824_ChIP-Seq_MCF-7_Human1.10258122
92* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09941791
93TCF4_23295773_ChIP-Seq_U87_Human1.09147848
94TET1_21490601_ChIP-Seq_MESCs_Mouse1.08518910
95KDM2B_26808549_Chip-Seq_JURKAT_Human1.08356868
96SCL_19346495_ChIP-Seq_HPC-7_Human1.07388916
97* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07155776
98AHR_22903824_ChIP-Seq_MCF-7_Human1.07068020
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.05345479
100ZNF274_21170338_ChIP-Seq_K562_Hela1.04481055
101KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.04368622
102RING1B_27294783_Chip-Seq_NPCs_Mouse1.03855574
103FUS_26573619_Chip-Seq_HEK293_Human1.03073260
104MYB_21317192_ChIP-Seq_ERMYB_Mouse1.02299773
105E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.01898840
106* VDR_24763502_ChIP-Seq_THP-1_Human1.01346783
107RUNX_20019798_ChIP-Seq_JUKART_Human1.01275066
108VDR_22108803_ChIP-Seq_LS180_Human1.00556525
109OCT4_19829295_ChIP-Seq_ESCs_Human1.00038482
110IRF8_21731497_ChIP-ChIP_J774_Mouse0.99993762
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99704086
112TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99452879
113* AR_19668381_ChIP-Seq_PC3_Human0.99452164
114RNF2_27304074_Chip-Seq_NSC_Mouse0.98058662
115SMC4_20622854_ChIP-Seq_HELA_Human0.97913610
116* VDR_24787735_ChIP-Seq_THP-1_Human0.97056940
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.96391117
118TP53_18474530_ChIP-ChIP_U2OS_Human0.96376218
119TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95697812
120IRF8_22096565_ChIP-ChIP_GC-B_Human0.94963848
121* RUNX2_22187159_ChIP-Seq_PCA_Human0.94924417
122NANOG_18555785_Chip-Seq_ESCs_Mouse0.94853612
123EGR1_19032775_ChIP-ChIP_M12_Human0.94008881
124TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.93636746
125NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93166179
126DNAJC2_21179169_ChIP-ChIP_NT2_Human0.92995335
127* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.92309004
128GATA1_19941826_ChIP-Seq_K562_Human0.92244289
129DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.92241274
130GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92163369
131WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.92126390
132POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91507917
133TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91507917
134* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.91271487
135PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.91153844
136PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91094455
137RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89082706
138SMAD3_21741376_ChIP-Seq_ESCs_Human0.88623633
139NRF2_20460467_ChIP-Seq_MEFs_Mouse0.88541778
140NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.88541778
141* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.88462519
142DPY_21335234_ChIP-Seq_ESCs_Mouse0.88420306
143EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.88192583
144CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.87705179
145* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.87598243
146* MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.87039925
147* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.86763498
148* SMAD3_21741376_ChIP-Seq_HESCs_Human0.86392364
149IGF1R_20145208_ChIP-Seq_DFB_Human0.85964711
150* CTNNB1_20460455_ChIP-Seq_HCT116_Human0.85872468
151RXR_22108803_ChIP-Seq_LS180_Human0.85608263
152* VDR_21846776_ChIP-Seq_THP-1_Human0.84288031
153FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.84014367
154GATA2_21666600_ChIP-Seq_HMVEC_Human0.83994158
155KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.83433065
156CTCF_27219007_Chip-Seq_Bcells_Human0.83250202
157* KLF4_19829295_ChIP-Seq_ESCs_Human0.82019534

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.09374591
2MP0003880_abnormal_central_pattern5.02686868
3MP0004270_analgesia3.90918103
4MP0003635_abnormal_synaptic_transmissio3.89786403
5MP0009745_abnormal_behavioral_response3.32828833
6MP0009046_muscle_twitch3.29908904
7MP0002064_seizures3.27645242
8MP0002063_abnormal_learning/memory/cond3.07124132
9MP0002272_abnormal_nervous_system2.87312950
10MP0001486_abnormal_startle_reflex2.84536146
11MP0000920_abnormal_myelination2.76804402
12MP0002572_abnormal_emotion/affect_behav2.70316247
13MP0001968_abnormal_touch/_nociception2.64674086
14MP0002734_abnormal_mechanical_nocicepti2.51638924
15MP0003329_amyloid_beta_deposits2.45047700
16MP0005423_abnormal_somatic_nervous2.40132832
17MP0002822_catalepsy2.34712801
18MP0001440_abnormal_grooming_behavior2.17971616
19MP0001501_abnormal_sleep_pattern2.15654837
20MP0003690_abnormal_glial_cell2.04949166
21MP0002736_abnormal_nociception_after2.02591746
22MP0004885_abnormal_endolymph2.02383300
23MP0008569_lethality_at_weaning2.01920772
24MP0000778_abnormal_nervous_system2.01814337
25MP0002067_abnormal_sensory_capabilities1.94238192
26MP0002735_abnormal_chemical_nociception1.89820743
27MP0001970_abnormal_pain_threshold1.83229353
28MP0005058_abnormal_lysosome_morphology1.81317525
29MP0002733_abnormal_thermal_nociception1.77605161
30MP0005409_darkened_coat_color1.75905367
31MP0004742_abnormal_vestibular_system1.68468683
32MP0004924_abnormal_behavior1.68353884
33MP0005386_behavior/neurological_phenoty1.68353884
34MP0001905_abnormal_dopamine_level1.67081119
35MP0001529_abnormal_vocalization1.63987085
36MP0006082_CNS_inflammation1.56697758
37MP0002184_abnormal_innervation1.55024567
38MP0005167_abnormal_blood-brain_barrier1.53918496
39MP0004142_abnormal_muscle_tone1.53051992
40MP0003634_abnormal_glial_cell1.51711094
41MP0002882_abnormal_neuron_morphology1.50655690
42MP0005171_absent_coat_pigmentation1.49632016
43MP0000955_abnormal_spinal_cord1.48180609
44MP0002557_abnormal_social/conspecific_i1.47800876
45MP0004811_abnormal_neuron_physiology1.47303271
46MP0002066_abnormal_motor_capabilities/c1.47287989
47MP0009780_abnormal_chondrocyte_physiolo1.47080752
48MP0000604_amyloidosis1.44996524
49MP0003633_abnormal_nervous_system1.41302210
50MP0003632_abnormal_nervous_system1.40839337
51MP0002229_neurodegeneration1.38510848
52MP0003631_nervous_system_phenotype1.38490674
53MP0003724_increased_susceptibility_to1.31539631
54MP0003436_decreased_susceptibility_to1.30258962
55MP0005551_abnormal_eye_electrophysiolog1.29346371
56MP0003879_abnormal_hair_cell1.27858465
57MP0004858_abnormal_nervous_system1.25329244
58MP0001984_abnormal_olfaction1.23188187
59MP0000569_abnormal_digit_pigmentation1.18600728
60MP0005166_decreased_susceptibility_to1.13036683
61MP0001502_abnormal_circadian_rhythm1.12865888
62MP0002419_abnormal_innate_immunity1.12172135
63MP0003075_altered_response_to1.08269619
64MP0001485_abnormal_pinna_reflex1.05906287
65MP0005646_abnormal_pituitary_gland1.05202763
66MP0003136_yellow_coat_color1.03533258
67MP0001188_hyperpigmentation1.03516670
68MP0008260_abnormal_autophagy1.03274467
69MP0002152_abnormal_brain_morphology1.03221480
70MP0004145_abnormal_muscle_electrophysio1.01316488
71MP0003191_abnormal_cellular_cholesterol1.00294586
72MP0001963_abnormal_hearing_physiology0.97768970
73MP0002090_abnormal_vision0.95479476
74MP0005000_abnormal_immune_tolerance0.95286333
75MP0001177_atelectasis0.95032394
76MP0008874_decreased_physiological_sensi0.94199193
77MP0004130_abnormal_muscle_cell0.90855382
78MP0002752_abnormal_somatic_nervous0.88908857
79MP0003183_abnormal_peptide_metabolism0.88209065
80MP0009278_abnormal_bone_marrow0.85401968
81MP0002998_abnormal_bone_remodeling0.84514429
82MP0005025_abnormal_response_to0.83501610
83MP0005645_abnormal_hypothalamus_physiol0.82865819
84MP0001835_abnormal_antigen_presentation0.82770903
85MP0002148_abnormal_hypersensitivity_rea0.82706140
86MP0005623_abnormal_meninges_morphology0.82177151
87MP0006276_abnormal_autonomic_nervous0.81454313
88MP0002909_abnormal_adrenal_gland0.81340570
89MP0001986_abnormal_taste_sensitivity0.80901075
90MP0005671_abnormal_response_to0.79379907
91MP0003123_paternal_imprinting0.76591110
92MP0003300_gastrointestinal_ulcer0.75249330
93MP0004510_myositis0.75031406
94MP0002069_abnormal_eating/drinking_beha0.74257324
95MP0001533_abnormal_skeleton_physiology0.71293575
96MP0005387_immune_system_phenotype0.71034696
97MP0001790_abnormal_immune_system0.71034696
98MP0005410_abnormal_fertilization0.70688628
99MP0000751_myopathy0.70334472
100MP0001348_abnormal_lacrimal_gland0.69135680
101MP0002133_abnormal_respiratory_system0.69034462
102MP0005388_respiratory_system_phenotype0.69034462
103MP0000343_altered_response_to0.67639662
104MP0004947_skin_inflammation0.66791953
105MP0003950_abnormal_plasma_membrane0.65925384
106MP0005535_abnormal_body_temperature0.63690521
107MP0003787_abnormal_imprinting0.63658353
108MP0004085_abnormal_heartbeat0.62765244
109MP0001299_abnormal_eye_distance/0.62120587
110MP0002723_abnormal_immune_serum0.61762023
111MP0002420_abnormal_adaptive_immunity0.59421245
112MP0001819_abnormal_immune_cell0.57696452
113MP0003828_pulmonary_edema0.57403076
114MP0000026_abnormal_inner_ear0.56558317
115MP0002452_abnormal_antigen_presenting0.56070468
116MP0003122_maternal_imprinting0.55890897
117MP0008872_abnormal_physiological_respon0.55381590
118MP0005195_abnormal_posterior_eye0.54600381
119MP0010678_abnormal_skin_adnexa0.54541980
120MP0003172_abnormal_lysosome_physiology0.54162943
121MP0005253_abnormal_eye_physiology0.52514281
122MP0001851_eye_inflammation0.50483798
123MP0001943_abnormal_respiration0.50268321
124MP0004484_altered_response_of0.49869027
125MP0000631_abnormal_neuroendocrine_gland0.49616089
126MP0000747_muscle_weakness0.49584027
127MP0003137_abnormal_impulse_conducting0.49018181
128MP0005310_abnormal_salivary_gland0.48778232
129MP0003938_abnormal_ear_development0.47869134
130MP0003303_peritoneal_inflammation0.47662021
131MP0010386_abnormal_urinary_bladder0.47381108
132MP0001664_abnormal_digestion0.47353070
133MP0003045_fibrosis0.45584481
134MP0004043_abnormal_pH_regulation0.45536386
135MP0000013_abnormal_adipose_tissue0.45277637
136MP0000015_abnormal_ear_pigmentation0.44935186

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.77643457
2Myokymia (HP:0002411)6.24326369
3Focal seizures (HP:0007359)5.05089951
4Neurofibrillary tangles (HP:0002185)4.92688386
5Action tremor (HP:0002345)4.41540648
6Epileptic encephalopathy (HP:0200134)4.39052843
7Atonic seizures (HP:0010819)4.32613090
8Cerebral inclusion bodies (HP:0100314)4.23930013
9Supranuclear gaze palsy (HP:0000605)4.20494894
10Visual hallucinations (HP:0002367)4.16585156
11Progressive cerebellar ataxia (HP:0002073)3.92402968
12Dysmetria (HP:0001310)3.91461599
13Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.81602187
14Degeneration of the lateral corticospinal tracts (HP:0002314)3.81602187
15Broad-based gait (HP:0002136)3.72373618
16Abnormality of the corticospinal tract (HP:0002492)3.63172219
17Intention tremor (HP:0002080)3.59954274
18Gaze-evoked nystagmus (HP:0000640)3.58250365
19Dialeptic seizures (HP:0011146)3.52573535
20Absence seizures (HP:0002121)3.51404757
21Hemiplegia (HP:0002301)3.47980258
22Sensory axonal neuropathy (HP:0003390)3.41586445
23Scanning speech (HP:0002168)3.33717026
24Annular pancreas (HP:0001734)3.33347137
25Spastic gait (HP:0002064)3.28293650
26Dysdiadochokinesis (HP:0002075)3.24251892
27Apathy (HP:0000741)3.19964710
28Febrile seizures (HP:0002373)3.19920900
29Abnormality of liposaccharide metabolism (HP:0010968)3.18268153
30Abnormality of glycosphingolipid metabolism (HP:0004343)3.18268153
31Abnormality of glycolipid metabolism (HP:0010969)3.18268153
32Hyperventilation (HP:0002883)3.16396579
33Generalized tonic-clonic seizures (HP:0002069)3.15959866
34Ankle clonus (HP:0011448)3.11538450
35Peripheral hypomyelination (HP:0007182)3.10465264
36Insidious onset (HP:0003587)3.06300800
37Termporal pattern (HP:0011008)3.06300800
38Diminished motivation (HP:0000745)2.97706663
39Tetraplegia (HP:0002445)2.96126623
40Increased cerebral lipofuscin (HP:0011813)2.92991729
41Onion bulb formation (HP:0003383)2.85438542
42Poor eye contact (HP:0000817)2.77015477
43Truncal ataxia (HP:0002078)2.71015522
44Abnormality of binocular vision (HP:0011514)2.70851069
45Diplopia (HP:0000651)2.70851069
46Urinary bladder sphincter dysfunction (HP:0002839)2.68879179
47Akinesia (HP:0002304)2.68867444
48Anxiety (HP:0000739)2.63088590
49Progressive inability to walk (HP:0002505)2.62629287
50Mutism (HP:0002300)2.62118228
51Impaired vibration sensation in the lower limbs (HP:0002166)2.54543642
52Dysostosis multiplex (HP:0000943)2.53618863
53Cerebral hypomyelination (HP:0006808)2.52518985
54Abnormal eating behavior (HP:0100738)2.51451359
55Memory impairment (HP:0002354)2.51444552
56Eczematoid dermatitis (HP:0000976)2.50945050
57Generalized myoclonic seizures (HP:0002123)2.50883855
58Abnormal social behavior (HP:0012433)2.47528033
59Impaired social interactions (HP:0000735)2.47528033
60Postural instability (HP:0002172)2.46899014
61Ocular albinism (HP:0001107)2.46686710
62Drooling (HP:0002307)2.46108488
63Excessive salivation (HP:0003781)2.46108488
64Parakeratosis (HP:0001036)2.45705130
65Bradykinesia (HP:0002067)2.43846061
66Clumsiness (HP:0002312)2.43402393
67Depression (HP:0000716)2.43033637
68Absent speech (HP:0001344)2.41182609
69Abnormality of the periventricular white matter (HP:0002518)2.40805840
70Hemiparesis (HP:0001269)2.40532233
71Rigidity (HP:0002063)2.39264998
72Amblyopia (HP:0000646)2.38912969
73Disinhibition (HP:0000734)2.38809023
74Delusions (HP:0000746)2.34574994
75Amyloidosis (HP:0011034)2.34341385
76Ventricular fibrillation (HP:0001663)2.33829897
77Stereotypic behavior (HP:0000733)2.30563483
78Neuronal loss in central nervous system (HP:0002529)2.27771634
79Megalencephaly (HP:0001355)2.27439923
80Craniofacial dystonia (HP:0012179)2.27264204
81Lower limb muscle weakness (HP:0007340)2.26997749
82Increased neuronal autofluorescent lipopigment (HP:0002074)2.25156471
83Abnormality of macrophages (HP:0004311)2.22859278
84Recurrent bacterial skin infections (HP:0005406)2.22563979
85Iris hypopigmentation (HP:0007730)2.20752366
86Dementia (HP:0000726)2.20751062
87Status epilepticus (HP:0002133)2.20528385
88Torticollis (HP:0000473)2.18341724
89Retinal dysplasia (HP:0007973)2.17725276
90Urinary urgency (HP:0000012)2.17568294
91Slow saccadic eye movements (HP:0000514)2.16152230
92Abnormality of saccadic eye movements (HP:0000570)2.16038947
93Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.14243795
94Loss of speech (HP:0002371)2.12542708
95Inappropriate behavior (HP:0000719)2.10927224
96Fetal akinesia sequence (HP:0001989)2.09188513
97Thickened helices (HP:0000391)2.06400994
98Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.06152477
99Recurrent abscess formation (HP:0002722)2.05224116
100Widely spaced teeth (HP:0000687)2.05172969
101Blue irides (HP:0000635)2.03289121
102Impaired smooth pursuit (HP:0007772)2.02199102
103Limb dystonia (HP:0002451)2.01509470
104Papilledema (HP:0001085)2.00750080
105Global brain atrophy (HP:0002283)1.99706717
106Focal dystonia (HP:0004373)1.99632616
107Genetic anticipation (HP:0003743)1.97124681
108Epileptiform EEG discharges (HP:0011182)1.96440920
109Lower limb asymmetry (HP:0100559)1.96324385
110Spastic tetraparesis (HP:0001285)1.95850876
111Inability to walk (HP:0002540)1.92989587
112Abnormal auditory evoked potentials (HP:0006958)1.92530325
113Gait ataxia (HP:0002066)1.91362094
114Agnosia (HP:0010524)1.90661915
115Choroideremia (HP:0001139)1.89742249
116Axonal loss (HP:0003447)1.89053209
117Sleep apnea (HP:0010535)1.88598333
118Psychosis (HP:0000709)1.86315548
119Abnormality of mucopolysaccharide metabolism (HP:0011020)1.85920995
120Abnormality of polysaccharide metabolism (HP:0011012)1.85920995
121Abnormality of glycosaminoglycan metabolism (HP:0004371)1.85920995
122Cerebral aneurysm (HP:0004944)1.85871316
123Abnormality of salivation (HP:0100755)1.85825423
124Recurrent gram-negative bacterial infections (HP:0005420)1.84372716
125Dynein arm defect of respiratory motile cilia (HP:0012255)1.84062442
126Absent/shortened dynein arms (HP:0200106)1.84062442
127Bundle branch block (HP:0011710)1.83705902
128Optic neuritis (HP:0100653)1.83336899
129Retrobulbar optic neuritis (HP:0100654)1.83336899
130Orchitis (HP:0100796)1.82991465
131Pheochromocytoma (HP:0002666)1.82704049
132EEG with generalized epileptiform discharges (HP:0011198)1.82436987
133Impaired vibratory sensation (HP:0002495)1.82434481
134Abnormality of the lower motor neuron (HP:0002366)1.82379266
135Aplasia involving bones of the upper limbs (HP:0009823)1.82106004
136Aplasia of the phalanges of the hand (HP:0009802)1.82106004
137Aplasia involving bones of the extremities (HP:0009825)1.82106004
138Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.81993947
139Mucopolysacchariduria (HP:0008155)1.81971427
140Increased circulating renin level (HP:0000848)1.81825613
141Bowel incontinence (HP:0002607)1.79556614
142Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.78939073
143Clonus (HP:0002169)1.78708306
144Rapidly progressive (HP:0003678)1.78201897
145Alacrima (HP:0000522)1.77944057
146Abnormality of ocular smooth pursuit (HP:0000617)1.76342490
147Obstructive sleep apnea (HP:0002870)1.73873616
148Postural tremor (HP:0002174)1.73313330
149Decreased motor nerve conduction velocity (HP:0003431)1.73216341

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.38048162
2NTRK33.37889922
3MAP3K92.72079878
4STK392.68389824
5TNIK2.61755751
6OXSR12.56701418
7RIPK42.45868117
8PRPF4B2.37879060
9MARK12.34223658
10CASK2.33376512
11RIPK12.30370671
12CDK192.27522069
13DAPK22.15535830
14PAK62.04861553
15MAP3K42.04845375
16MINK11.88589735
17NTRK11.79392187
18KSR21.73779860
19MAP2K71.72751537
20FES1.61836956
21NTRK21.61657401
22PNCK1.58653978
23FGR1.55512893
24CDK51.53002700
25PLK21.44632014
26PKN11.42969829
27UHMK11.40293856
28BCR1.34907526
29ARAF1.34649222
30CAMKK11.33291393
31EPHB11.32189474
32MAP3K131.26789938
33TYRO31.25683173
34MAPK121.25130806
35CAMKK21.23926309
36MAP3K111.23153717
37PRKD31.20856063
38CAMK2B1.20267005
39LATS21.19290491
40BLK1.18752512
41GRK51.18523682
42WNK11.16789416
43CAMK2A1.11515450
44MAPK131.11467596
45NEK61.09905583
46MAP2K41.08566098
47SGK31.07631278
48KSR11.07336638
49MAP3K121.07154193
50SGK21.06986642
51BMPR21.06509138
52PTK2B1.05624436
53TNK21.01662984
54DAPK11.00811884
55SGK4941.00636906
56SGK2231.00636906
57PRKCG0.98415520
58MAPKAPK50.96434085
59CDK140.95910636
60MAP3K20.94876917
61ROCK20.94137728
62CDK150.92876830
63CDK180.92670138
64CSNK1G20.92552187
65ALK0.86990698
66WNK40.86268608
67CAMK40.84661041
68JAK20.84640845
69STK110.84605638
70SIK20.83969248
71MARK20.83566256
72JAK10.82966275
73CDK11A0.81255731
74FGFR20.81004895
75CAMK2D0.80761398
76PDPK10.76323679
77MOS0.75165214
78SYK0.74615954
79FYN0.73636173
80CAMK10.73191887
81ICK0.69638368
82PRKCH0.68184684
83SGK10.68042624
84DDR20.67819074
85CSNK1A1L0.67702370
86TYK20.67689857
87PHKG10.66779350
88PHKG20.66779350
89PRKCE0.66319674
90DYRK1A0.66097957
91RAF10.65994843
92PDK10.63498109
93MAP2K30.61805818
94PAK30.61738226
95CSNK1G30.61135551
96CSK0.59555405
97CLK10.59316835
98TAOK20.59311222
99CAMK2G0.59119071
100MAPK70.58941649
101CAMK1G0.56855079
102MET0.54738710
103ZAP700.54661913
104RET0.51512497
105STK380.51472939
106MUSK0.50667436
107PRKCQ0.50534252
108CAMK1D0.49954474
109MAP3K30.48357226
110CDC42BPA0.48136223
111DAPK30.47406096
112TAOK10.46934214
113MAP3K10.45656117
114DMPK0.43922445
115PRKG10.42915236
116LIMK10.42791593
117MAP4K10.42543393
118GRK70.41051631
119HCK0.40889537
120PRKCZ0.39324258
121RPS6KA30.38482765
122ERN10.38072309
123IRAK20.37982929
124MAPK100.37378676
125BRAF0.37138349
126MAP3K140.36985008
127CSNK1G10.35602033
128PINK10.35056890
129PBK0.34429301
130PRKD10.32515448

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.33609344
2Synaptic vesicle cycle_Homo sapiens_hsa047212.75598517
3Glutamatergic synapse_Homo sapiens_hsa047242.67199559
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.62209863
5Circadian entrainment_Homo sapiens_hsa047132.51233992
6Long-term potentiation_Homo sapiens_hsa047202.50251934
7GABAergic synapse_Homo sapiens_hsa047272.49933425
8Morphine addiction_Homo sapiens_hsa050322.43577022
9Olfactory transduction_Homo sapiens_hsa047402.36035357
10Amphetamine addiction_Homo sapiens_hsa050312.13569132
11Salivary secretion_Homo sapiens_hsa049702.11286856
12Dopaminergic synapse_Homo sapiens_hsa047281.92726245
13Long-term depression_Homo sapiens_hsa047301.89851933
14Serotonergic synapse_Homo sapiens_hsa047261.82018915
15Cholinergic synapse_Homo sapiens_hsa047251.77118602
16Gastric acid secretion_Homo sapiens_hsa049711.76500104
17Collecting duct acid secretion_Homo sapiens_hsa049661.67118292
18Renin secretion_Homo sapiens_hsa049241.66434696
19Axon guidance_Homo sapiens_hsa043601.60350071
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.57488748
21Phototransduction_Homo sapiens_hsa047441.56605899
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.55487616
23Oxytocin signaling pathway_Homo sapiens_hsa049211.53185098
24Taste transduction_Homo sapiens_hsa047421.51730513
25Calcium signaling pathway_Homo sapiens_hsa040201.47707842
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.43889609
27Insulin secretion_Homo sapiens_hsa049111.41450814
28Cocaine addiction_Homo sapiens_hsa050301.41063450
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.33894617
30Osteoclast differentiation_Homo sapiens_hsa043801.33427694
31GnRH signaling pathway_Homo sapiens_hsa049121.27424735
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23910741
33cAMP signaling pathway_Homo sapiens_hsa040241.19163409
34Gap junction_Homo sapiens_hsa045401.17444098
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.16804786
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.14082625
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.12226354
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.09200674
39Tuberculosis_Homo sapiens_hsa051521.08517918
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.07243701
41Vibrio cholerae infection_Homo sapiens_hsa051101.02057606
42ErbB signaling pathway_Homo sapiens_hsa040121.01991570
43Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.01213803
44Vascular smooth muscle contraction_Homo sapiens_hsa042701.00328239
45Phospholipase D signaling pathway_Homo sapiens_hsa040721.00297604
46Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.99891685
47Leishmaniasis_Homo sapiens_hsa051400.97507816
48Ether lipid metabolism_Homo sapiens_hsa005650.94757461
49Estrogen signaling pathway_Homo sapiens_hsa049150.94159314
50B cell receptor signaling pathway_Homo sapiens_hsa046620.93699665
51Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93097579
52Other glycan degradation_Homo sapiens_hsa005110.91426026
53Glioma_Homo sapiens_hsa052140.91307384
54Type II diabetes mellitus_Homo sapiens_hsa049300.90489800
55Toll-like receptor signaling pathway_Homo sapiens_hsa046200.90414244
56Melanogenesis_Homo sapiens_hsa049160.89993679
57Pancreatic secretion_Homo sapiens_hsa049720.89988288
58Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89518008
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88521183
60Cardiac muscle contraction_Homo sapiens_hsa042600.86873410
61Staphylococcus aureus infection_Homo sapiens_hsa051500.86414099
62Sphingolipid signaling pathway_Homo sapiens_hsa040710.84942397
63Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.84106650
64Dorso-ventral axis formation_Homo sapiens_hsa043200.83978637
65Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82628815
66Alzheimers disease_Homo sapiens_hsa050100.81153860
67Rheumatoid arthritis_Homo sapiens_hsa053230.77809043
68Steroid biosynthesis_Homo sapiens_hsa001000.77229223
69Ras signaling pathway_Homo sapiens_hsa040140.76417587
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.75447923
71Choline metabolism in cancer_Homo sapiens_hsa052310.74637166
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73583129
73MAPK signaling pathway_Homo sapiens_hsa040100.70138940
74Endocytosis_Homo sapiens_hsa041440.69979417
75Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.69977333
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.69826516
77Fatty acid elongation_Homo sapiens_hsa000620.67705996
78Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66914562
79Renal cell carcinoma_Homo sapiens_hsa052110.66191117
80Oxidative phosphorylation_Homo sapiens_hsa001900.66170050
81African trypanosomiasis_Homo sapiens_hsa051430.65352611
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64366966
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63345409
84Pertussis_Homo sapiens_hsa051330.63173977
85Chemokine signaling pathway_Homo sapiens_hsa040620.63060846
86VEGF signaling pathway_Homo sapiens_hsa043700.60925847
87Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58998324
88Sphingolipid metabolism_Homo sapiens_hsa006000.58828248
89Dilated cardiomyopathy_Homo sapiens_hsa054140.58184972
90mTOR signaling pathway_Homo sapiens_hsa041500.56522674
91Thyroid hormone synthesis_Homo sapiens_hsa049180.56514064
92Amoebiasis_Homo sapiens_hsa051460.56465045
93Non-small cell lung cancer_Homo sapiens_hsa052230.55628870
94Bile secretion_Homo sapiens_hsa049760.54980031
95Rap1 signaling pathway_Homo sapiens_hsa040150.54534695
96HIF-1 signaling pathway_Homo sapiens_hsa040660.54019585
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52430688
98Malaria_Homo sapiens_hsa051440.51804078
99T cell receptor signaling pathway_Homo sapiens_hsa046600.50506104
100Phagosome_Homo sapiens_hsa041450.50045857
101Inositol phosphate metabolism_Homo sapiens_hsa005620.48860061
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47519145
103Ovarian steroidogenesis_Homo sapiens_hsa049130.46479437
104Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.46384771
105AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46031604
106Vitamin B6 metabolism_Homo sapiens_hsa007500.46018669
107Toxoplasmosis_Homo sapiens_hsa051450.45816190
108Prion diseases_Homo sapiens_hsa050200.45585644
109Alcoholism_Homo sapiens_hsa050340.44927794
110Acute myeloid leukemia_Homo sapiens_hsa052210.44910506
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.44355848
112Oocyte meiosis_Homo sapiens_hsa041140.43623181
113Salmonella infection_Homo sapiens_hsa051320.42865888
114Prolactin signaling pathway_Homo sapiens_hsa049170.42114049
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41903405
116Endometrial cancer_Homo sapiens_hsa052130.41384299
117TNF signaling pathway_Homo sapiens_hsa046680.41172424
118Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36644770
119Mineral absorption_Homo sapiens_hsa049780.35236318
120Type I diabetes mellitus_Homo sapiens_hsa049400.34909087
121Tight junction_Homo sapiens_hsa045300.34137099
122Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.32978482
123Lysosome_Homo sapiens_hsa041420.32817516
124Platelet activation_Homo sapiens_hsa046110.32371403
125Carbohydrate digestion and absorption_Homo sapiens_hsa049730.32223864
126Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32202517
127Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.32130543

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