GBAS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)8.21946469
2muscle filament sliding (GO:0030049)7.91904014
3actin-myosin filament sliding (GO:0033275)7.91904014
4cardiac myofibril assembly (GO:0055003)7.67538430
5myofibril assembly (GO:0030239)7.30670080
6negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.78584991
7actin-mediated cell contraction (GO:0070252)6.70042277
8regulation of relaxation of muscle (GO:1901077)6.68344849
9tricarboxylic acid cycle (GO:0006099)6.57337283
10regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.51998738
11positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.35935837
12cardiac muscle contraction (GO:0060048)6.32126902
13regulation of skeletal muscle contraction (GO:0014819)6.28760042
14negative regulation of potassium ion transmembrane transport (GO:1901380)6.20010120
15regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO6.07667844
16heart contraction (GO:0060047)5.83859489
17heart process (GO:0003015)5.83859489
18sarcoplasmic reticulum calcium ion transport (GO:0070296)5.82945509
19regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.72966162
20regulation of actin filament-based movement (GO:1903115)5.68663842
21cardiac muscle cell development (GO:0055013)5.48882432
22regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.47211969
23regulation of cell communication by electrical coupling (GO:0010649)5.45615259
24actomyosin structure organization (GO:0031032)5.45254268
25striated muscle contraction (GO:0006941)5.45017829
26regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.40692474
27cardiac muscle tissue morphogenesis (GO:0055008)5.32747233
28plasma membrane repair (GO:0001778)5.32277034
29regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.27096518
30regulation of acyl-CoA biosynthetic process (GO:0050812)5.21181992
31cardiac cell development (GO:0055006)5.17383313
32cardiac muscle hypertrophy (GO:0003300)5.03723018
33regulation of sarcomere organization (GO:0060297)4.98709151
34ventricular cardiac muscle tissue morphogenesis (GO:0055010)4.93419011
35mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.88580289
36mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.86089237
37muscle tissue morphogenesis (GO:0060415)4.85307994
38actin filament-based movement (GO:0030048)4.84696018
39striated muscle hypertrophy (GO:0014897)4.82312635
40regulation of striated muscle contraction (GO:0006942)4.79885277
41regulation of membrane repolarization (GO:0060306)4.75580019
42regulation of cofactor metabolic process (GO:0051193)4.72185837
43regulation of coenzyme metabolic process (GO:0051196)4.72185837
44respiratory electron transport chain (GO:0022904)4.64752039
45carnitine shuttle (GO:0006853)4.63389032
46energy coupled proton transport, down electrochemical gradient (GO:0015985)4.60144121
47ATP synthesis coupled proton transport (GO:0015986)4.60144121
48ventricular cardiac muscle cell action potential (GO:0086005)4.59757979
49adult heart development (GO:0007512)4.58662380
50electron transport chain (GO:0022900)4.51929397
51heart trabecula formation (GO:0060347)4.47725291
52response to muscle activity (GO:0014850)4.45130696
53response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.40292241
54positive regulation of potassium ion transmembrane transporter activity (GO:1901018)4.37105631
55skeletal muscle contraction (GO:0003009)4.34357135
56bundle of His cell to Purkinje myocyte communication (GO:0086069)4.34274857
57muscle hypertrophy (GO:0014896)4.30317024
58cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.27450409
59regulation of the force of heart contraction (GO:0002026)4.05052446
60skeletal muscle fiber development (GO:0048741)4.01732736
61negative regulation of cardiac muscle cell apoptotic process (GO:0010667)3.97020789
62cell communication involved in cardiac conduction (GO:0086065)3.93812461
63ubiquinone biosynthetic process (GO:0006744)3.91013495
64myotube cell development (GO:0014904)3.88043308
65regulation of cardiac muscle contraction (GO:0055117)3.87931626
66relaxation of cardiac muscle (GO:0055119)3.87672624
67fatty acid transmembrane transport (GO:1902001)3.85617686
68* oxidative phosphorylation (GO:0006119)3.84297892
69negative regulation of protein localization to cell surface (GO:2000009)3.83090940
70regulation of cardiac muscle cell contraction (GO:0086004)3.81185693
71muscle fiber development (GO:0048747)3.80475519
72regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.77378799
73glycogen catabolic process (GO:0005980)3.74867561
74negative regulation of striated muscle cell apoptotic process (GO:0010664)3.73847695
75NADH metabolic process (GO:0006734)3.73227162
76creatine metabolic process (GO:0006600)3.71811375
77muscle contraction (GO:0006936)3.69359370
78regulation of sulfur metabolic process (GO:0042762)3.68694897
79regulation of heart rate (GO:0002027)3.68619423
80cardiac muscle cell action potential involved in contraction (GO:0086002)3.68535890
81cardiac muscle adaptation (GO:0014887)3.68111796
82cardiac muscle hypertrophy in response to stress (GO:0014898)3.68111796
83muscle hypertrophy in response to stress (GO:0003299)3.68111796
84negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.66909481
85cell communication by electrical coupling (GO:0010644)3.65863948
86cardiac muscle cell action potential (GO:0086001)3.64656521
87ubiquinone metabolic process (GO:0006743)3.64097674
88muscle cell cellular homeostasis (GO:0046716)3.63541998
892-oxoglutarate metabolic process (GO:0006103)3.63047644
90positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.58410517
91response to inactivity (GO:0014854)3.55397876
92regulation of calcium ion transmembrane transporter activity (GO:1901019)3.53977396
93regulation of calcium ion transmembrane transport (GO:1903169)3.53977396
94membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.51192477
95succinate metabolic process (GO:0006105)3.50317813
96cardiac conduction (GO:0061337)3.49713686
97muscle system process (GO:0003012)3.49291961
98pyrimidine ribonucleoside catabolic process (GO:0046133)3.47551421
99striated muscle cell development (GO:0055002)3.42978441
100negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.42523162
101negative regulation of calcium ion transmembrane transport (GO:1903170)3.42523162
102glycogen biosynthetic process (GO:0005978)3.42509575
103glucan biosynthetic process (GO:0009250)3.42509575
104striated muscle adaptation (GO:0014888)3.41533575
105skeletal muscle adaptation (GO:0043501)3.40907733
106negative regulation of potassium ion transport (GO:0043267)3.40842716
107regulation of muscle contraction (GO:0006937)3.40591724
108regulation of heart rate by cardiac conduction (GO:0086091)3.40374956
109glucan catabolic process (GO:0009251)3.39604623
110regulation of ATP catabolic process (GO:1903289)3.38865143
111regulation of ATPase activity (GO:0043462)3.38865143
112carnitine transmembrane transport (GO:1902603)3.37694799
113negative regulation of muscle hypertrophy (GO:0014741)3.35638033
114regulation of heart contraction (GO:0008016)3.33063709
115cytidine catabolic process (GO:0006216)3.32949357
116gluconeogenesis (GO:0006094)3.30397456
117positive regulation of cation channel activity (GO:2001259)3.20722798
118positive regulation of mitochondrial fission (GO:0090141)3.18848550
119cellular polysaccharide catabolic process (GO:0044247)3.17029497
120regulation of potassium ion transmembrane transporter activity (GO:1901016)3.16952131
121intracellular lipid transport (GO:0032365)3.11914915
122polysaccharide catabolic process (GO:0000272)3.08834647
123positive regulation of potassium ion transport (GO:0043268)3.08714679
124positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.07582852
125regulation of sequestering of triglyceride (GO:0010889)3.07176112
126branched-chain amino acid catabolic process (GO:0009083)3.03654449
127neuronal action potential propagation (GO:0019227)3.03524157
128quinone biosynthetic process (GO:1901663)2.96429234
129skeletal muscle tissue development (GO:0007519)2.95770177
130otic vesicle formation (GO:0030916)2.95564233
131relaxation of muscle (GO:0090075)2.91390042
132positive regulation of potassium ion transmembrane transport (GO:1901381)2.89982092
133aspartate family amino acid catabolic process (GO:0009068)2.87053394
134hexose biosynthetic process (GO:0019319)2.86625448
135regulation of muscle system process (GO:0090257)2.77080271

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.41800402
2EP300_21415370_ChIP-Seq_HL-1_Mouse4.83886469
3* ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.64370569
4ESR1_20079471_ChIP-ChIP_T-47D_Human3.65043990
5TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.54166758
6* TBX20_22080862_ChIP-Seq_HEART_Mouse3.30805919
7* TBX20_22328084_ChIP-Seq_HEART_Mouse3.30805919
8MEF2A_21415370_ChIP-Seq_HL-1_Mouse3.04628896
9IGF1R_20145208_ChIP-Seq_DFB_Human2.99704592
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.96291562
11RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.80364007
12CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.79125818
13CDX2_19796622_ChIP-Seq_MESCs_Mouse2.71938473
14GATA4_21415370_ChIP-Seq_HL-1_Mouse2.69965773
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.17456632
16TAF15_26573619_Chip-Seq_HEK293_Human2.15204282
17EZH2_22144423_ChIP-Seq_EOC_Human2.13306910
18RARG_19884340_ChIP-ChIP_MEFs_Mouse2.06987579
19ZFP57_27257070_Chip-Seq_ESCs_Mouse1.98069894
20CBX2_27304074_Chip-Seq_ESCs_Mouse1.88511247
21EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.81729639
22PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.80177599
23NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.78128403
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.69687154
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.61279077
26TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59207210
27SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.49696710
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.47899012
29FUS_26573619_Chip-Seq_HEK293_Human1.46748465
30SUZ12_27294783_Chip-Seq_NPCs_Mouse1.45834545
31PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.44413438
32SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.43745317
33ZNF263_19887448_ChIP-Seq_K562_Human1.41890974
34MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.41573703
35SRF_21415370_ChIP-Seq_HL-1_Mouse1.41222098
36PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.38195920
37BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.37912855
38ZNF274_21170338_ChIP-Seq_K562_Hela1.36718343
39CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36282674
40GATA1_22025678_ChIP-Seq_K562_Human1.35513431
41GATA2_21666600_ChIP-Seq_HMVEC_Human1.34249578
42ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.33724646
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.33593829
44BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.30736050
45GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28495473
46ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.28180090
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26450630
48EWS_26573619_Chip-Seq_HEK293_Human1.25917895
49SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.24843732
50NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23726378
51GBX2_23144817_ChIP-Seq_PC3_Human1.23418167
52CJUN_26792858_Chip-Seq_BT549_Human1.23301038
53EZH2_18974828_ChIP-Seq_MESCs_Mouse1.23191200
54RNF2_18974828_ChIP-Seq_MESCs_Mouse1.23191200
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22398187
56VDR_22108803_ChIP-Seq_LS180_Human1.21778379
57TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.20504256
58TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.19703742
59ER_23166858_ChIP-Seq_MCF-7_Human1.19604413
60BCAT_22108803_ChIP-Seq_LS180_Human1.18763625
61CRX_20693478_ChIP-Seq_RETINA_Mouse1.18731777
62WT1_19549856_ChIP-ChIP_CCG9911_Human1.17733534
63CBP_20019798_ChIP-Seq_JUKART_Human1.17467737
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17467737
65EZH2_27304074_Chip-Seq_ESCs_Mouse1.17234078
66PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.16490731
67TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.14605496
68RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.14578573
69SMAD4_21799915_ChIP-Seq_A2780_Human1.12318384
70MTF2_20144788_ChIP-Seq_MESCs_Mouse1.11773698
71NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11448005
72NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11448005
73TRIM28_21343339_ChIP-Seq_HEK293_Human1.10284147
74THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.09863677
75SOX9_26525672_Chip-Seq_HEART_Mouse1.09253341
76RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08908605
77LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.07492251
78P53_22387025_ChIP-Seq_ESCs_Mouse1.07395579
79WDR5_24793694_ChIP-Seq_LNCAP_Human1.06892631
80SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.05162179
81SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04295648
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04266918
83CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04251211
84SALL1_21062744_ChIP-ChIP_HESCs_Human1.03454926
85PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03287934
86FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.02893617
87CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.02446566
88* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02061807
89E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.01115117
90TAL1_26923725_Chip-Seq_HPCs_Mouse1.01041354
91EZH2_27294783_Chip-Seq_ESCs_Mouse1.00837716
92ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.00571086
93ISL1_27105846_Chip-Seq_CPCs_Mouse1.00465169
94P300_19829295_ChIP-Seq_ESCs_Human1.00454326
95TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99130802
96OCT4_21477851_ChIP-Seq_ESCs_Mouse0.96732022
97TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96396365
98SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96371388
99TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95949082
100CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.94954682
101NANOG_18555785_Chip-Seq_ESCs_Mouse0.94891681
102SMAD_19615063_ChIP-ChIP_OVARY_Human0.94497049
103SOX2_21211035_ChIP-Seq_LN229_Gbm0.94340943
104NFE2_27457419_Chip-Seq_LIVER_Mouse0.92864830
105STAT3_23295773_ChIP-Seq_U87_Human0.92030489
106* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.90854565
107AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90630493
108PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.89922863
109RARB_27405468_Chip-Seq_BRAIN_Mouse0.89794577
110TCF4_23295773_ChIP-Seq_U87_Human0.89646410
111ESR2_21235772_ChIP-Seq_MCF-7_Human0.89395886
112RNF2_27304074_Chip-Seq_NSC_Mouse0.89085453
113LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88694815
114CLOCK_20551151_ChIP-Seq_293T_Human0.88489449
115E2F1_18555785_Chip-Seq_ESCs_Mouse0.88213050
116SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.87831487
117PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.87033826
118JARID2_20064375_ChIP-Seq_MESCs_Mouse0.84492090
119EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.83363266
120UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83171985
121SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.82974547
122HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.82112688
123PPAR_26484153_Chip-Seq_NCI-H1993_Human0.81390971
124JARID2_20075857_ChIP-Seq_MESCs_Mouse0.81339682
125NANOG_19829295_ChIP-Seq_ESCs_Human0.80070139
126SOX2_19829295_ChIP-Seq_ESCs_Human0.80070139
127EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.79660022
128FOXH1_21741376_ChIP-Seq_ESCs_Human0.79659725
129ESR1_21235772_ChIP-Seq_MCF-7_Human0.79378772
130SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.79085861
131AR_21572438_ChIP-Seq_LNCaP_Human0.79022399
132NR3C1_21868756_ChIP-Seq_MCF10A_Human0.78314477
133* OCT4_20526341_ChIP-Seq_ESCs_Human0.78067398
134AUTS2_25519132_ChIP-Seq_293T-REX_Human0.77423538
135PIAS1_25552417_ChIP-Seq_VCAP_Human0.76968152
136TDRD3_21172665_ChIP-Seq_MCF-7_Human0.75958933
137CTCF_27219007_Chip-Seq_Bcells_Human0.75729109
138WT1_25993318_ChIP-Seq_PODOCYTE_Human0.75267937
139NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.73908716
140PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.73574163
141SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.73411339
142LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.73337988
143GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.72615685
144CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.71670544
145DROSHA_22980978_ChIP-Seq_HELA_Human0.69525485
146KLF5_20875108_ChIP-Seq_MESCs_Mouse0.68887996
147PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.68806176
148OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.68457269
149SMAD4_21741376_ChIP-Seq_HESCs_Human0.68124075

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis6.03130829
2MP0003646_muscle_fatigue5.87861634
3MP0004084_abnormal_cardiac_muscle5.34299503
4MP0000751_myopathy5.09378153
5MP0000749_muscle_degeneration4.79007169
6MP0004036_abnormal_muscle_relaxation4.40758033
7MP0004215_abnormal_myocardial_fiber4.29130495
8MP0005330_cardiomyopathy3.61704505
9MP0004145_abnormal_muscle_electrophysio3.43566928
10MP0002972_abnormal_cardiac_muscle3.18197268
11MP0004087_abnormal_muscle_fiber3.08548174
12MP0005620_abnormal_muscle_contractility2.96345143
13MP0002106_abnormal_muscle_physiology2.84490309
14MP0008775_abnormal_heart_ventricle2.75118880
15MP0004484_altered_response_of2.61136726
16MP0003137_abnormal_impulse_conducting2.57794996
17MP0000750_abnormal_muscle_regeneration2.54285289
18MP0004130_abnormal_muscle_cell2.54224603
19MP0001544_abnormal_cardiovascular_syste2.53707654
20MP0005385_cardiovascular_system_phenoty2.53707654
21MP0005369_muscle_phenotype2.34816240
22MP0010630_abnormal_cardiac_muscle2.34254151
23MP0002269_muscular_atrophy2.30230414
24MP0000747_muscle_weakness2.23036766
25MP0000759_abnormal_skeletal_muscle2.20957572
26MP0006138_congestive_heart_failure2.20541369
27MP0004085_abnormal_heartbeat2.04271350
28MP0006036_abnormal_mitochondrial_physio2.02956272
29MP0003828_pulmonary_edema1.98027995
30MP0003221_abnormal_cardiomyocyte_apopto1.97597329
31MP0002332_abnormal_exercise_endurance1.73231437
32MP0004233_abnormal_muscle_weight1.72293063
33MP0003950_abnormal_plasma_membrane1.71272906
34MP0004510_myositis1.69271143
35MP0001984_abnormal_olfaction1.61352378
36MP0002127_abnormal_cardiovascular_syste1.59501638
37MP0003136_yellow_coat_color1.44417478
38MP0003567_abnormal_fetal_cardiomyocyte1.25892869
39MP0000343_altered_response_to1.21234617
40MP0004147_increased_porphyrin_level1.20687846
41MP0004043_abnormal_pH_regulation1.12631025
42MP0006035_abnormal_mitochondrial_morpho1.11288735
43MP0002653_abnormal_ependyma_morphology1.04957567
44MP0005666_abnormal_adipose_tissue1.04674423
45MP0000266_abnormal_heart_morphology1.03040332
46MP0002108_abnormal_muscle_morphology1.01394221
47MP0003279_aneurysm1.01208234
48MP0000230_abnormal_systemic_arterial0.91746289
49MP0005253_abnormal_eye_physiology0.91015550
50MP0001299_abnormal_eye_distance/0.90146389
51MP0005167_abnormal_blood-brain_barrier0.88264330
52MP0005670_abnormal_white_adipose0.88031656
53MP0003011_delayed_dark_adaptation0.87707315
54MP0002234_abnormal_pharynx_morphology0.85994359
55MP0005165_increased_susceptibility_to0.85482280
56MP0010368_abnormal_lymphatic_system0.80605308
57MP0000013_abnormal_adipose_tissue0.77964027
58MP0005266_abnormal_metabolism0.77862767
59MP0001879_abnormal_lymphatic_vessel0.71696329
60MP0006276_abnormal_autonomic_nervous0.71611084
61MP0006072_abnormal_retinal_apoptosis0.71096629
62MP0001661_extended_life_span0.70893437
63MP0005375_adipose_tissue_phenotype0.69664601
64MP0005248_abnormal_Harderian_gland0.66927454
65MP0004859_abnormal_synaptic_plasticity0.66736265
66MP0002128_abnormal_blood_circulation0.65631566
67MP0002877_abnormal_melanocyte_morpholog0.65094585
68MP0002909_abnormal_adrenal_gland0.64047288
69MP0003656_abnormal_erythrocyte_physiolo0.59350236
70MP0008789_abnormal_olfactory_epithelium0.59329795
71MP0000733_abnormal_muscle_development0.58692148
72MP0000778_abnormal_nervous_system0.58584391
73MP0005451_abnormal_body_composition0.56932914
74MP0003880_abnormal_central_pattern0.55305260
75MP0005584_abnormal_enzyme/coenzyme_acti0.54308807
76MP0002009_preneoplasia0.54078010
77MP0000372_irregular_coat_pigmentation0.54016903
78MP0001502_abnormal_circadian_rhythm0.52061355
79MP0005623_abnormal_meninges_morphology0.52046472
80MP0002249_abnormal_larynx_morphology0.50965230
81MP0002971_abnormal_brown_adipose0.50871595
82MP0002734_abnormal_mechanical_nocicepti0.50756255
83MP0005535_abnormal_body_temperature0.50373906
84MP0000762_abnormal_tongue_morphology0.49424681
85MP0004185_abnormal_adipocyte_glucose0.49310067
86MP0004272_abnormal_basement_membrane0.49185130
87MP0000003_abnormal_adipose_tissue0.49152121
88MP0002078_abnormal_glucose_homeostasis0.48875562
89MP0003186_abnormal_redox_activity0.46161129
90MP0000049_abnormal_middle_ear0.45868075
91MP0000631_abnormal_neuroendocrine_gland0.45546927
92MP0005386_behavior/neurological_phenoty0.45054771
93MP0004924_abnormal_behavior0.45054771
94MP0001486_abnormal_startle_reflex0.44192192
95MP0002066_abnormal_motor_capabilities/c0.43947854
96MP0008569_lethality_at_weaning0.43728223
97MP0005645_abnormal_hypothalamus_physiol0.43695601
98MP0003122_maternal_imprinting0.42927076
99MP0000767_abnormal_smooth_muscle0.42690584
100MP0000026_abnormal_inner_ear0.41843289
101MP0002067_abnormal_sensory_capabilities0.40716145
102MP0003948_abnormal_gas_homeostasis0.40248918
103MP0005083_abnormal_biliary_tract0.39601329
104MP0008438_abnormal_cutaneous_collagen0.38865249
105MP0009780_abnormal_chondrocyte_physiolo0.38312348
106MP0005275_abnormal_skin_tensile0.37536212
107MP0005503_abnormal_tendon_morphology0.37369107
108MP0003566_abnormal_cell_adhesion0.37181988
109MP0005551_abnormal_eye_electrophysiolog0.36898061
110MP0002752_abnormal_somatic_nervous0.36745329
111MP0008260_abnormal_autophagy0.36351426
112MP0001727_abnormal_embryo_implantation0.36204510
113MP0005171_absent_coat_pigmentation0.36048063
114MP0003195_calcinosis0.34785415
115MP0002925_abnormal_cardiovascular_devel0.33601250
116MP0001784_abnormal_fluid_regulation0.30490344
117MP0005646_abnormal_pituitary_gland0.28899710
118MP0002638_abnormal_pupillary_reflex0.28628703
119MP0001485_abnormal_pinna_reflex0.27793442
120MP0005595_abnormal_vascular_smooth0.27400714
121MP0005388_respiratory_system_phenotype0.26338474
122MP0002133_abnormal_respiratory_system0.26338474
123MP0002822_catalepsy0.26155744
124MP0001614_abnormal_blood_vessel0.25669019
125MP0004858_abnormal_nervous_system0.24182084
126MP0002735_abnormal_chemical_nociception0.22992985
127MP0001529_abnormal_vocalization0.22938060
128MP0004270_analgesia0.21405796
129MP0003941_abnormal_skin_development0.19685737
130MP0009250_abnormal_appendicular_skeleto0.18796026
131MP0005334_abnormal_fat_pad0.18727888
132MP0005452_abnormal_adipose_tissue0.18643954
133MP0005187_abnormal_penis_morphology0.17936783
134MP0002272_abnormal_nervous_system0.17531312
135MP0004142_abnormal_muscle_tone0.16961103

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.73359182
2Exercise-induced muscle cramps (HP:0003710)6.70028367
3Exercise-induced myalgia (HP:0003738)6.59016786
4Calf muscle hypertrophy (HP:0008981)6.49426578
5Muscle hypertrophy of the lower extremities (HP:0008968)6.20316001
6Ventricular tachycardia (HP:0004756)5.64431885
7Atrial fibrillation (HP:0005110)5.45080736
8Myoglobinuria (HP:0002913)5.16055681
9Abnormality of the calf musculature (HP:0001430)5.14662324
10Primary atrial arrhythmia (HP:0001692)5.04116201
11Muscle fiber splitting (HP:0003555)5.00144253
12Abnormality of the left ventricular outflow tract (HP:0011103)4.99053444
13Subaortic stenosis (HP:0001682)4.99053444
14Supraventricular tachycardia (HP:0004755)4.86795456
15Supraventricular arrhythmia (HP:0005115)4.75057413
16Lipoatrophy (HP:0100578)4.71622765
17Hyporeflexia of lower limbs (HP:0002600)4.49476125
18EMG: myopathic abnormalities (HP:0003458)4.26787836
19Muscle fiber inclusion bodies (HP:0100299)4.23882173
20Palpitations (HP:0001962)4.14004421
21Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.13413265
22Dilated cardiomyopathy (HP:0001644)4.06681285
23Prolonged QT interval (HP:0001657)3.96996411
24Syncope (HP:0001279)3.96015792
25Rhabdomyolysis (HP:0003201)3.90738794
26Bundle branch block (HP:0011710)3.90190211
27Acute necrotizing encephalopathy (HP:0006965)3.80163763
28Abnormal mitochondria in muscle tissue (HP:0008316)3.78916832
29Right ventricular cardiomyopathy (HP:0011663)3.74677019
30Asymmetric septal hypertrophy (HP:0001670)3.71077648
31Nemaline bodies (HP:0003798)3.69509221
32Myotonia (HP:0002486)3.65049413
33Type 1 muscle fiber predominance (HP:0003803)3.55641223
34Calcaneovalgus deformity (HP:0001848)3.47581879
35Ventricular arrhythmia (HP:0004308)3.43186411
36Increased connective tissue (HP:0009025)3.40951690
37Ulnar deviation of the wrist (HP:0003049)3.38714953
38Hepatic necrosis (HP:0002605)3.37813678
39Heart block (HP:0012722)3.26310137
40Progressive macrocephaly (HP:0004481)3.24455146
41Difficulty running (HP:0009046)3.20421925
42Deformed tarsal bones (HP:0008119)3.14661370
43Acute encephalopathy (HP:0006846)3.12658307
44Abnormal atrioventricular conduction (HP:0005150)3.07241018
45Muscle stiffness (HP:0003552)3.06087825
46Mitochondrial inheritance (HP:0001427)3.01735250
47Left ventricular hypertrophy (HP:0001712)3.01461797
48Ventricular fibrillation (HP:0001663)3.01026271
49Hepatocellular necrosis (HP:0001404)2.99346882
50Absent phalangeal crease (HP:0006109)2.97673729
51Frequent falls (HP:0002359)2.90004680
52Abnormal EKG (HP:0003115)2.87009075
53Atrioventricular block (HP:0001678)2.85473377
54Increased CSF lactate (HP:0002490)2.84782994
55Exercise intolerance (HP:0003546)2.78507025
56Neck muscle weakness (HP:0000467)2.76312478
57Pheochromocytoma (HP:0002666)2.76202819
58Distal lower limb muscle weakness (HP:0009053)2.73172973
59Conjunctival hamartoma (HP:0100780)2.70423838
60Areflexia of lower limbs (HP:0002522)2.65577234
61Neuroendocrine neoplasm (HP:0100634)2.54816835
62Rimmed vacuoles (HP:0003805)2.52229099
63Abnormality of skeletal muscle fiber size (HP:0012084)2.51941958
64Abnormal finger flexion creases (HP:0006143)2.51917373
65Distal arthrogryposis (HP:0005684)2.51234061
66Increased variability in muscle fiber diameter (HP:0003557)2.50827994
67Ketoacidosis (HP:0001993)2.42417530
68Increased muscle lipid content (HP:0009058)2.42143916
69Lactic acidosis (HP:0003128)2.41433053
70Abnormality of alanine metabolism (HP:0010916)2.41135576
71Hyperalaninemia (HP:0003348)2.41135576
72Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.41135576
73Malignant hyperthermia (HP:0002047)2.37763896
74Cerebral edema (HP:0002181)2.34213292
75Neoplasm of the adrenal gland (HP:0100631)2.31887579
76Difficulty climbing stairs (HP:0003551)2.30096102
77Palmoplantar keratoderma (HP:0000982)2.26514491
78Respiratory failure (HP:0002878)2.25154634
79Hypoglycemic coma (HP:0001325)2.23606220
80Increased intramyocellular lipid droplets (HP:0012240)2.22735994
81Abnormality of fatty-acid metabolism (HP:0004359)2.22003074
82Generalized aminoaciduria (HP:0002909)2.19607191
83Proximal amyotrophy (HP:0007126)2.19054604
84Generalized muscle weakness (HP:0003324)2.16961495
85Ragged-red muscle fibers (HP:0003200)2.16918268
86Scapular winging (HP:0003691)2.13970941
87Abnormality of dicarboxylic acid metabolism (HP:0010995)2.11161468
88Dicarboxylic aciduria (HP:0003215)2.11161468
89Abnormality of the foot musculature (HP:0001436)2.08451600
90Facial diplegia (HP:0001349)2.07045847
91Tinnitus (HP:0000360)2.05424970
92Progressive muscle weakness (HP:0003323)2.04066074
93Limb-girdle muscle atrophy (HP:0003797)2.03785493
94Gowers sign (HP:0003391)2.02991531
95Foot dorsiflexor weakness (HP:0009027)2.02352497
96Myopathic facies (HP:0002058)2.00687200
97Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.00659056
98Decreased activity of mitochondrial respiratory chain (HP:0008972)2.00659056
99Esophageal neoplasm (HP:0100751)1.99179278
100Neoplasm of head and neck (HP:0012288)1.99179278
101Fetal akinesia sequence (HP:0001989)1.98316980
102Muscular dystrophy (HP:0003560)1.98007948
103Abnormality of glycolysis (HP:0004366)1.97541612
104Increased serum pyruvate (HP:0003542)1.97541612
105Central scotoma (HP:0000603)1.90900990
106Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.90621594
107Hip contracture (HP:0003273)1.88305000
108Centrally nucleated skeletal muscle fibers (HP:0003687)1.88274212
109Weak cry (HP:0001612)1.87924196
110Mildly elevated creatine phosphokinase (HP:0008180)1.85520196
111Abnormality of the musculature of the pelvis (HP:0001469)1.84846009
112Abnormality of the hip-girdle musculature (HP:0001445)1.84846009
113Bulbar palsy (HP:0001283)1.82885989
114Abnormality of the calcaneus (HP:0008364)1.82082082
115Abnormality of the shoulder girdle musculature (HP:0001435)1.81529237
116EMG: neuropathic changes (HP:0003445)1.81112668
117Round ear (HP:0100830)1.81055270
118Steppage gait (HP:0003376)1.80762110
119Hamartoma of the eye (HP:0010568)1.79420609
120Optic disc pallor (HP:0000543)1.78619177
121Respiratory insufficiency due to muscle weakness (HP:0002747)1.73225519
122Lower limb amyotrophy (HP:0007210)1.73190418
123Shoulder girdle muscle weakness (HP:0003547)1.69480137
124Hyperkalemia (HP:0002153)1.67698472
125Long clavicles (HP:0000890)1.61434103
126Reduced antithrombin III activity (HP:0001976)1.60576732
127Waddling gait (HP:0002515)1.56503015
128Pelvic girdle muscle weakness (HP:0003749)1.54022285
129Limb-girdle muscle weakness (HP:0003325)1.53644874
130Distal lower limb amyotrophy (HP:0008944)1.49239305
131Broad-based gait (HP:0002136)1.47281988

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN6.02618372
2TTN4.90761606
3PHKG23.92886922
4PHKG13.92886922
5MYLK3.81681680
6LMTK23.34591623
7PDK33.12282715
8PDK43.12282715
9MUSK3.07409840
10STK242.64454923
11PINK12.57303328
12PIK3CA2.55163657
13BCKDK2.33998429
14DMPK2.30127147
15PKN22.13099552
16NEK12.11491483
17TIE12.05061168
18PDK22.01699241
19MARK11.87241051
20BCR1.83481790
21ZAK1.82025904
22STK38L1.63007307
23TRIB31.51866457
24GRK71.44836685
25TRPM71.35531547
26CCNB11.34817818
27NME11.26412209
28NEK91.21667403
29WNK41.12854869
30ILK1.12340026
31CAMK2D1.12000419
32SGK21.11716408
33MAP2K31.11090436
34MAP4K21.08115492
35MAPKAPK31.06437093
36LATS11.01275605
37ROCK10.95564090
38PAK30.93019456
39INSRR0.90110615
40MAPK120.85603900
41PRKD10.85228515
42MAP3K70.84912030
43CDC42BPA0.84788436
44CAMK2B0.83882828
45MOS0.82959893
46EPHA30.82216872
47CSNK1G20.82064104
48SGK30.81952650
49PRKAA10.81771212
50SGK2230.81679451
51SGK4940.81679451
52CSNK1G30.80544820
53NTRK20.78684407
54CSNK1A1L0.77212181
55DYRK1B0.76929814
56ERBB30.76709624
57LIMK10.75817266
58DYRK30.73535497
59RPS6KA40.71761915
60TNIK0.70561522
61PRKAA20.68524400
62PIK3CG0.63122505
63CAMK2A0.62509041
64MAP3K30.60831811
65WNK10.60158930
66CSNK1G10.60127127
67CAMK40.59914026
68PRPF4B0.59299360
69CDK190.58866597
70PRKCE0.57814529
71STK390.56392520
72PKN10.56268967
73PRKD30.56159358
74EPHB10.55979588
75FLT30.55686610
76RPS6KL10.55367352
77RPS6KC10.55367352
78STK40.53918328
79PAK60.53756448
80CAMK2G0.52862198
81PRKCH0.51746963
82SCYL20.50749949
83RPS6KA60.49801353
84MAP3K50.49234272
85PRKACB0.47526112
86ROCK20.47185263
87CAMK10.46835968
88BMPR20.46566633
89DAPK30.46359135
90PRKACA0.46110493
91MAP2K40.45891197
92MAP2K60.44896376
93PRKG20.43996393
94CASK0.43441671
95MAP2K70.43135919
96TESK10.42706400
97MAPK70.40593453
98STK380.39099969
99ERBB40.35605886
100PBK0.32764817
101ARAF0.32611929
102MAPK40.32239668
103UHMK10.28493773
104CDK30.28313248
105SGK10.28212661
106MAPK150.28191336
107MAPK110.27765167
108RPS6KA20.27673780
109PRKACG0.27442290
110PRKG10.27262803
111PTK2B0.26890508
112MAP3K40.26627600
113PIM20.26163043
114MET0.24706261
115TGFBR20.24621169
116EIF2AK10.23286553
117EPHA40.23239405
118PDK10.22828940
119MAPK130.22597206
120PLK20.22588304
121MAPK100.22457979
122MAP3K120.22293459
123CAMKK20.22181066
124AKT30.21277942
125PDPK10.20683086
126PRKDC0.20130845
127AKT20.19990509
128NEK60.19722011
129WNK30.18359820
130ADRBK10.17266320
131CDK50.17047552
132TAOK30.16530881
133FER0.16428136
134MAP2K10.16324422
135CDK140.15939711
136KDR0.15452230
137NME20.14883336
138DYRK1A0.14066576
139KSR20.13587764
140SIK30.12906981
141RPS6KA30.12888143
142RPS6KA10.12719150
143MAPKAPK20.12412298

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000206.19973357
2Cardiac muscle contraction_Homo sapiens_hsa042604.49424584
3Parkinsons disease_Homo sapiens_hsa050124.02625681
4Oxidative phosphorylation_Homo sapiens_hsa001903.95712569
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.61863513
6Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.55696141
7Dilated cardiomyopathy_Homo sapiens_hsa054143.53603616
8Propanoate metabolism_Homo sapiens_hsa006403.10162158
9Alzheimers disease_Homo sapiens_hsa050102.97416759
10Huntingtons disease_Homo sapiens_hsa050162.62967134
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.54473847
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.50156387
13Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.33168666
14Carbon metabolism_Homo sapiens_hsa012002.20296388
15Fatty acid degradation_Homo sapiens_hsa000712.16549168
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.95501808
17Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.81007086
18Fatty acid metabolism_Homo sapiens_hsa012121.68289660
19Pyruvate metabolism_Homo sapiens_hsa006201.66008410
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.59426620
21Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.50093135
22Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.41591637
23Fatty acid elongation_Homo sapiens_hsa000621.39867518
24Viral myocarditis_Homo sapiens_hsa054161.34675522
25Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.31451657
26Pentose phosphate pathway_Homo sapiens_hsa000301.27676045
27Nitrogen metabolism_Homo sapiens_hsa009101.22153087
28Regulation of autophagy_Homo sapiens_hsa041401.15111361
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.14128346
30cGMP-PKG signaling pathway_Homo sapiens_hsa040221.12182624
31Glucagon signaling pathway_Homo sapiens_hsa049221.09732798
32Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.04449148
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.04195196
34Arginine biosynthesis_Homo sapiens_hsa002201.04111910
35Starch and sucrose metabolism_Homo sapiens_hsa005001.03725850
36Calcium signaling pathway_Homo sapiens_hsa040201.01416379
37Galactose metabolism_Homo sapiens_hsa000520.95919985
38Insulin signaling pathway_Homo sapiens_hsa049100.93278683
39Insulin resistance_Homo sapiens_hsa049310.92820918
40Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91559532
41Butanoate metabolism_Homo sapiens_hsa006500.89556811
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.86927311
43Oxytocin signaling pathway_Homo sapiens_hsa049210.86226687
44Cysteine and methionine metabolism_Homo sapiens_hsa002700.78593040
45Vascular smooth muscle contraction_Homo sapiens_hsa042700.77311402
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73452665
47Adipocytokine signaling pathway_Homo sapiens_hsa049200.73036878
48Circadian rhythm_Homo sapiens_hsa047100.72540347
49Biosynthesis of amino acids_Homo sapiens_hsa012300.70371652
50HIF-1 signaling pathway_Homo sapiens_hsa040660.68215177
51Tryptophan metabolism_Homo sapiens_hsa003800.66525510
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65730848
53Insulin secretion_Homo sapiens_hsa049110.65585675
54Gastric acid secretion_Homo sapiens_hsa049710.64395631
55Fructose and mannose metabolism_Homo sapiens_hsa000510.64282629
56Tight junction_Homo sapiens_hsa045300.64281588
57Focal adhesion_Homo sapiens_hsa045100.63295283
58Olfactory transduction_Homo sapiens_hsa047400.63228019
59Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61781469
60Circadian entrainment_Homo sapiens_hsa047130.60779716
61Tyrosine metabolism_Homo sapiens_hsa003500.59128150
62Phototransduction_Homo sapiens_hsa047440.58378397
63AMPK signaling pathway_Homo sapiens_hsa041520.56833926
64Renin secretion_Homo sapiens_hsa049240.56442639
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.56195038
66Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53764670
67Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52041104
68cAMP signaling pathway_Homo sapiens_hsa040240.48560784
69Steroid biosynthesis_Homo sapiens_hsa001000.48138379
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.48002295
71Type II diabetes mellitus_Homo sapiens_hsa049300.45232811
72PPAR signaling pathway_Homo sapiens_hsa033200.42160017
73Cholinergic synapse_Homo sapiens_hsa047250.41107267
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38008182
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36936945
76beta-Alanine metabolism_Homo sapiens_hsa004100.36162175
77Ovarian steroidogenesis_Homo sapiens_hsa049130.34930545
78Lysine degradation_Homo sapiens_hsa003100.34567515
79Taste transduction_Homo sapiens_hsa047420.34272474
80Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33881134
81Aldosterone synthesis and secretion_Homo sapiens_hsa049250.32664763
82Oocyte meiosis_Homo sapiens_hsa041140.32608216
83Histidine metabolism_Homo sapiens_hsa003400.32453001
84Peroxisome_Homo sapiens_hsa041460.31856800
85Metabolic pathways_Homo sapiens_hsa011000.31080718
86Arginine and proline metabolism_Homo sapiens_hsa003300.30924360
87Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.30364352
88RNA degradation_Homo sapiens_hsa030180.29927775
89Pancreatic secretion_Homo sapiens_hsa049720.28986240
90Amphetamine addiction_Homo sapiens_hsa050310.26859454
91Glutathione metabolism_Homo sapiens_hsa004800.26525891
92GnRH signaling pathway_Homo sapiens_hsa049120.23877919
93ECM-receptor interaction_Homo sapiens_hsa045120.22997923
94Sulfur relay system_Homo sapiens_hsa041220.22766516
95Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.22253058
96Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.22204048
97Axon guidance_Homo sapiens_hsa043600.20425449
98FoxO signaling pathway_Homo sapiens_hsa040680.20253003
99Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19381527
100Dopaminergic synapse_Homo sapiens_hsa047280.19325025
101Platelet activation_Homo sapiens_hsa046110.18672435
102Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.18562858
103Phenylalanine metabolism_Homo sapiens_hsa003600.18506493
104Glutamatergic synapse_Homo sapiens_hsa047240.18389586
105Sulfur metabolism_Homo sapiens_hsa009200.17760243
106Serotonergic synapse_Homo sapiens_hsa047260.17673136
107Regulation of actin cytoskeleton_Homo sapiens_hsa048100.17518370
108Gap junction_Homo sapiens_hsa045400.16532684
109Morphine addiction_Homo sapiens_hsa050320.16373243
110Salivary secretion_Homo sapiens_hsa049700.16131947
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.15847053
112Adherens junction_Homo sapiens_hsa045200.15708390
113Fatty acid biosynthesis_Homo sapiens_hsa000610.15357081
114Vibrio cholerae infection_Homo sapiens_hsa051100.13560142
115Long-term potentiation_Homo sapiens_hsa047200.13324493
116Melanogenesis_Homo sapiens_hsa049160.13096265
117Arachidonic acid metabolism_Homo sapiens_hsa005900.12172982
118Collecting duct acid secretion_Homo sapiens_hsa049660.11391749
119Amoebiasis_Homo sapiens_hsa051460.09535660
120GABAergic synapse_Homo sapiens_hsa047270.08262948
121Leukocyte transendothelial migration_Homo sapiens_hsa046700.07286464
122Protein export_Homo sapiens_hsa030600.07255029
123Melanoma_Homo sapiens_hsa052180.05890058
124MAPK signaling pathway_Homo sapiens_hsa040100.05214572
125Purine metabolism_Homo sapiens_hsa002300.02721125
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.02533968
127Prolactin signaling pathway_Homo sapiens_hsa049170.02221536

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