GC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1exogenous drug catabolic process (GO:0042738)7.91095853
2epoxygenase P450 pathway (GO:0019373)7.88228290
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.60324366
4L-phenylalanine catabolic process (GO:0006559)7.60324366
5omega-hydroxylase P450 pathway (GO:0097267)7.28143582
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.25950741
7L-phenylalanine metabolic process (GO:0006558)7.25950741
8aromatic amino acid family catabolic process (GO:0009074)6.78039578
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.45492404
10tryptophan catabolic process (GO:0006569)6.05038965
11indole-containing compound catabolic process (GO:0042436)6.05038965
12indolalkylamine catabolic process (GO:0046218)6.05038965
13kynurenine metabolic process (GO:0070189)5.95681838
14bile acid biosynthetic process (GO:0006699)5.87430970
15tryptophan metabolic process (GO:0006568)5.71096240
16drug metabolic process (GO:0017144)5.70496110
17urea metabolic process (GO:0019627)5.69935945
18urea cycle (GO:0000050)5.69935945
19phenylpropanoid metabolic process (GO:0009698)5.69253341
20negative regulation of fibrinolysis (GO:0051918)5.67886823
21glyoxylate metabolic process (GO:0046487)5.66549333
22high-density lipoprotein particle remodeling (GO:0034375)5.66249649
23alpha-linolenic acid metabolic process (GO:0036109)5.64025999
24regulation of fibrinolysis (GO:0051917)5.44653124
25protein carboxylation (GO:0018214)5.41939112
26peptidyl-glutamic acid carboxylation (GO:0017187)5.41939112
27cysteine metabolic process (GO:0006534)5.40407762
28oxidative demethylation (GO:0070989)5.38636847
29sulfur amino acid catabolic process (GO:0000098)5.36543151
30complement activation, alternative pathway (GO:0006957)5.29329037
31regulation of protein activation cascade (GO:2000257)5.27618622
32nitrogen cycle metabolic process (GO:0071941)5.23672235
33serine family amino acid catabolic process (GO:0009071)5.14712315
34bile acid metabolic process (GO:0008206)5.10436487
35ethanol metabolic process (GO:0006067)4.99205897
36regulation of cholesterol esterification (GO:0010872)4.98712887
37negative regulation of protein activation cascade (GO:2000258)4.97904083
38reverse cholesterol transport (GO:0043691)4.95962060
39aromatic amino acid family metabolic process (GO:0009072)4.93115217
40regulation of complement activation (GO:0030449)4.90223516
41protein-lipid complex remodeling (GO:0034368)4.86050194
42macromolecular complex remodeling (GO:0034367)4.86050194
43plasma lipoprotein particle remodeling (GO:0034369)4.86050194
44tyrosine metabolic process (GO:0006570)4.82507493
45regulation of triglyceride catabolic process (GO:0010896)4.81684696
46fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.79902940
47homocysteine metabolic process (GO:0050667)4.79488108
48phospholipid efflux (GO:0033700)4.66595351
49acylglycerol homeostasis (GO:0055090)4.65983514
50triglyceride homeostasis (GO:0070328)4.65983514
51alpha-amino acid catabolic process (GO:1901606)4.64424499
52negative regulation of cholesterol transport (GO:0032375)4.64089760
53negative regulation of sterol transport (GO:0032372)4.64089760
54S-adenosylmethionine metabolic process (GO:0046500)4.63458591
55amino-acid betaine metabolic process (GO:0006577)4.61861744
56lysine catabolic process (GO:0006554)4.55479879
57lysine metabolic process (GO:0006553)4.55479879
58cellular ketone body metabolic process (GO:0046950)4.49384269
59plasma lipoprotein particle clearance (GO:0034381)4.47496631
60bile acid and bile salt transport (GO:0015721)4.47048171
61glycine metabolic process (GO:0006544)4.43373219
62imidazole-containing compound metabolic process (GO:0052803)4.36467141
63regulation of plasminogen activation (GO:0010755)4.33195565
64negative regulation of complement activation (GO:0045916)4.32300093
65indolalkylamine metabolic process (GO:0006586)4.30481450
66cholesterol efflux (GO:0033344)4.29669092
67cellular glucuronidation (GO:0052695)4.29181102
68cellular amino acid catabolic process (GO:0009063)4.26890047
69coenzyme catabolic process (GO:0009109)4.26490771
70glutamate metabolic process (GO:0006536)4.25758306
71cellular biogenic amine catabolic process (GO:0042402)4.19712277
72amine catabolic process (GO:0009310)4.19712277
73regulation of humoral immune response (GO:0002920)4.19652937
74serine family amino acid metabolic process (GO:0009069)4.18593913
75low-density lipoprotein particle remodeling (GO:0034374)4.17278124
76acute-phase response (GO:0006953)4.16222969
77benzene-containing compound metabolic process (GO:0042537)4.08828377
78plasma lipoprotein particle assembly (GO:0034377)4.08117473
79ethanol oxidation (GO:0006069)4.07106964
80negative regulation of blood coagulation (GO:0030195)4.06807940
81negative regulation of hemostasis (GO:1900047)4.06807940
82cellular modified amino acid catabolic process (GO:0042219)4.03886292
83fibrinolysis (GO:0042730)4.03378740
84dicarboxylic acid biosynthetic process (GO:0043650)4.02727227
85serine family amino acid biosynthetic process (GO:0009070)4.01678114
86arginine metabolic process (GO:0006525)4.00159894
87aldehyde catabolic process (GO:0046185)3.99542898
88drug catabolic process (GO:0042737)3.98256417
89ketone body metabolic process (GO:1902224)3.88999929
90blood coagulation, intrinsic pathway (GO:0007597)3.86982529
91very-low-density lipoprotein particle assembly (GO:0034379)3.81697264
92uronic acid metabolic process (GO:0006063)3.81017861
93glucuronate metabolic process (GO:0019585)3.81017861
94negative regulation of lipase activity (GO:0060192)3.80974982
95phospholipid homeostasis (GO:0055091)3.80727805
96positive regulation of triglyceride lipase activity (GO:0061365)3.78907268
97positive regulation of lipoprotein lipase activity (GO:0051006)3.78907268
98intestinal cholesterol absorption (GO:0030299)3.78183287
99negative regulation of wound healing (GO:0061045)3.77988747
100positive regulation of lipid catabolic process (GO:0050996)3.77979152
101cholesterol homeostasis (GO:0042632)3.77484071
102heme transport (GO:0015886)3.77445874
103alkaloid metabolic process (GO:0009820)3.77389069
104negative regulation of coagulation (GO:0050819)3.76095281
105cofactor catabolic process (GO:0051187)3.74426816
106carboxylic acid catabolic process (GO:0046395)3.73840607
107organic acid catabolic process (GO:0016054)3.73840607
108regulation of bile acid biosynthetic process (GO:0070857)3.72231222
109sterol homeostasis (GO:0055092)3.71315337
110complement activation, classical pathway (GO:0006958)3.70452111
111protein activation cascade (GO:0072376)3.70009616
112complement activation (GO:0006956)3.69155183
113short-chain fatty acid metabolic process (GO:0046459)3.69144145
114plasma lipoprotein particle organization (GO:0071827)3.68390742
115protein-lipid complex assembly (GO:0065005)3.66262463
116regulation of cholesterol homeostasis (GO:2000188)3.64970613
117acetyl-CoA metabolic process (GO:0006084)3.60352670
118cytolysis (GO:0019835)3.59763141
119positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.57059690
120opsonization (GO:0008228)3.52270632
121hormone catabolic process (GO:0042447)3.51296559
122flavonoid metabolic process (GO:0009812)3.50883608
123lipoprotein metabolic process (GO:0042157)3.49431594
124xenobiotic metabolic process (GO:0006805)3.47526619
125polyketide metabolic process (GO:0030638)3.41848284
126doxorubicin metabolic process (GO:0044598)3.41848284
127daunorubicin metabolic process (GO:0044597)3.41848284
128killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.40485571
129disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.40485571
130xenobiotic catabolic process (GO:0042178)3.38602374
131positive regulation of blood coagulation (GO:0030194)3.38012347
132positive regulation of hemostasis (GO:1900048)3.38012347
133negative regulation of humoral immune response (GO:0002921)3.33565459
134positive regulation of coagulation (GO:0050820)3.28590088
135primary alcohol metabolic process (GO:0034308)3.24956049

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.42584173
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.22362748
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse6.96633122
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.55835362
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.29818981
6* CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.10355219
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.82568828
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.06772824
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.06528586
10* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.04458099
11* ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.8993726
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.99062013
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.96909416
14GBX2_23144817_ChIP-Seq_PC3_Human1.65366865
15FOXA2_19822575_ChIP-Seq_HepG2_Human1.64025846
16CLOCK_20551151_ChIP-Seq_293T_Human1.60195309
17POU3F2_20337985_ChIP-ChIP_501MEL_Human1.59558193
18* HTT_18923047_ChIP-ChIP_STHdh_Human1.46087585
19GATA1_22025678_ChIP-Seq_K562_Human1.43882971
20PIAS1_25552417_ChIP-Seq_VCAP_Human1.42275669
21* HNF4A_19822575_ChIP-Seq_HepG2_Human1.41575554
22NFE2_27457419_Chip-Seq_LIVER_Mouse1.36971255
23SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29143572
24EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.27918991
25EZH2_27294783_Chip-Seq_NPCs_Mouse1.26776056
26IGF1R_20145208_ChIP-Seq_DFB_Human1.26190634
27THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.22595379
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.20746170
29STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.19054728
30RXRA_24833708_ChIP-Seq_LIVER_Mouse1.18584215
31ER_23166858_ChIP-Seq_MCF-7_Human1.16303845
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15845016
33AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13154693
34ESR1_15608294_ChIP-ChIP_MCF-7_Human1.11216610
35PHF8_20622853_ChIP-Seq_HELA_Human1.07026947
36CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05976297
37EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04455063
38EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04035211
39HNFA_21074721_ChIP-Seq_CACO-2_Human1.02227451
40ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01641588
41ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00720110
42IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00606225
43ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00314357
44SOX2_20726797_ChIP-Seq_SW620_Human1.00062678
45FOXA1_25329375_ChIP-Seq_VCAP_Human0.98810647
46FOXA1_27270436_Chip-Seq_PROSTATE_Human0.98810647
47STAT3_18555785_Chip-Seq_ESCs_Mouse0.98757643
48CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.98402534
49OCT4_18555785_Chip-Seq_ESCs_Mouse0.97495155
50PCGF2_27294783_Chip-Seq_NPCs_Mouse0.97149874
51FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95734217
52PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.95169013
53SOX2_27498859_Chip-Seq_STOMACH_Mouse0.94841840
54RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.94838406
55SOX2_18555785_Chip-Seq_ESCs_Mouse0.94639801
56CRX_20693478_ChIP-Seq_RETINA_Mouse0.94586274
57FLI1_27457419_Chip-Seq_LIVER_Mouse0.93762052
58NFYA_21822215_ChIP-Seq_K562_Human0.93687847
59P53_22387025_ChIP-Seq_ESCs_Mouse0.93237793
60SMAD1_18555785_Chip-Seq_ESCs_Mouse0.92081248
61FOXA1_21572438_ChIP-Seq_LNCaP_Human0.91828856
62TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.91487456
63RUNX1_27457419_Chip-Seq_LIVER_Mouse0.91369284
64NANOG_18555785_Chip-Seq_ESCs_Mouse0.91339441
65SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90652384
66GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.90313855
67OCT4_21477851_ChIP-Seq_ESCs_Mouse0.88803507
68CTCF_18555785_Chip-Seq_ESCs_Mouse0.88601706
69SOX2_19829295_ChIP-Seq_ESCs_Human0.86394007
70NANOG_19829295_ChIP-Seq_ESCs_Human0.86394007
71* STAT3_23295773_ChIP-Seq_U87_Human0.85956716
72GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.85504291
73ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.85416289
74E2F1_18555785_Chip-Seq_ESCs_Mouse0.85388334
75TP53_18474530_ChIP-ChIP_U2OS_Human0.85336630
76NMYC_18555785_Chip-Seq_ESCs_Mouse0.85324826
77PU1_27457419_Chip-Seq_LIVER_Mouse0.84880205
78GATA6_21074721_ChIP-Seq_CACO-2_Human0.84668129
79ESRRB_18555785_Chip-Seq_ESCs_Mouse0.84477239
80IRF8_22096565_ChIP-ChIP_GC-B_Human0.84347882
81ETV2_25802403_ChIP-Seq_MESCs_Mouse0.84319460
82KLF4_18555785_Chip-Seq_ESCs_Mouse0.84138665
83GATA4_25053715_ChIP-Seq_YYC3_Human0.84118994
84CBP_20019798_ChIP-Seq_JUKART_Human0.83332704
85IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.83332704
86AUTS2_25519132_ChIP-Seq_293T-REX_Human0.83234454
87RARG_19884340_ChIP-ChIP_MEFs_Mouse0.83162123
88PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.82971462
89P300_18555785_Chip-Seq_ESCs_Mouse0.82671487
90CMYC_18555785_Chip-Seq_ESCs_Mouse0.82401908
91ZFX_18555785_Chip-Seq_ESCs_Mouse0.81509331
92SMAD4_21799915_ChIP-Seq_A2780_Human0.81077325
93TCF4_22108803_ChIP-Seq_LS180_Human0.80093738
94CTBP1_25329375_ChIP-Seq_LNCAP_Human0.79653470
95SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79421071
96SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.78439142
97BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.78245565
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.77106554
99KAP1_22055183_ChIP-Seq_ESCs_Mouse0.76812499
100ZNF263_19887448_ChIP-Seq_K562_Human0.75265361
101Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.75036063
102RARA_24833708_ChIP-Seq_LIVER_Mouse0.73803535
103SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.73562169
104AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.70251093
105SALL4_18804426_ChIP-ChIP_XEN_Mouse0.69793027
106NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.69587656
107* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.68419226
108NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.66833583
109NRF2_20460467_ChIP-Seq_MEFs_Mouse0.66833583
110ESR2_21235772_ChIP-Seq_MCF-7_Human0.66697789
111FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.63622292
112RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.63467096
113RARB_24833708_ChIP-Seq_LIVER_Mouse0.63068269
114NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.60148603
115BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.59691327
116RAD21_21589869_ChIP-Seq_MESCs_Mouse0.58670832
117NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.58167019
118CEBPB_22108803_ChIP-Seq_LS180_Human0.56938721
119FOXA1_25552417_ChIP-Seq_VCAP_Human0.55376880
120FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.54191635
121FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.52085260
122EGR1_19032775_ChIP-ChIP_M12_Human0.52007316
123LXR_22292898_ChIP-Seq_THP-1_Human0.51913997
124PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.51034595
125MYC_19915707_ChIP-ChIP_AK7_Human0.50579558
126E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.50371098
127STAT1_17558387_ChIP-Seq_HELA_Human0.49225469
128CBP_21632823_ChIP-Seq_H3396_Human0.49166141
129ESET_19884257_ChIP-Seq_ESCs_Mouse0.48911233
130* AR_20517297_ChIP-Seq_VCAP_Human0.48890090
131STAT3_1855785_ChIP-Seq_MESCs_Mouse0.48394800
132PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.47207236
133PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.46516861
134TAF15_26573619_Chip-Seq_HEK293_Human0.45817602
135ESR1_21235772_ChIP-Seq_MCF-7_Human0.44968383
136* P53_21459846_ChIP-Seq_SAOS-2_Human0.43566031
137FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.43549339
138CDX2_20551321_ChIP-Seq_CACO-2_Human0.42726064
139FOXO3_23340844_ChIP-Seq_DLD1_Human0.42262609
140PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.41877950
141CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.41011203
142GATA6_25053715_ChIP-Seq_YYC3_Human0.40849490
143BCAT_22108803_ChIP-Seq_LS180_Human0.40779932
144ESR1_20079471_ChIP-ChIP_T-47D_Human0.40659649
145GATA1_19941827_ChIP-Seq_MEL_Mouse0.40148059
146TAF2_19829295_ChIP-Seq_ESCs_Human0.40028161
147SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.39407092
148ERG_21242973_ChIP-ChIP_JURKAT_Human0.38069046
149* GATA1_19941826_ChIP-Seq_K562_Human0.37930213
150* GATA2_19941826_ChIP-Seq_K562_Human0.37732120
151* PPAR_26484153_Chip-Seq_NCI-H1993_Human0.37352932
152LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.36589130
153MYC_27129775_Chip-Seq_CORNEA_Mouse0.36169080
154SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.35849010
155STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.35834744
156CDX2_22108803_ChIP-Seq_LS180_Human0.34389029
157GATA3_24758297_ChIP-Seq_MCF-7_Human0.34359978
158NCOR_22424771_ChIP-Seq_293T_Human0.34308587
159GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.33788759
160ERG_20517297_ChIP-Seq_VCAP_Human0.33764673
161BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.33596648

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.34485062
2MP0005360_urolithiasis7.53855848
3MP0005085_abnormal_gallbladder_physiolo6.42933037
4MP0005365_abnormal_bile_salt6.18558433
5MP0008875_abnormal_xenobiotic_pharmacok5.18889973
6MP0003806_abnormal_nucleotide_metabolis4.26601965
7MP0003252_abnormal_bile_duct3.90766837
8MP0010329_abnormal_lipoprotein_level3.61998287
9MP0009840_abnormal_foam_cell3.35321524
10MP0005083_abnormal_biliary_tract3.14489716
11MP0003195_calcinosis2.90096893
12MP0005332_abnormal_amino_acid2.75839348
13MP0001666_abnormal_nutrient_absorption2.58438579
14MP0003191_abnormal_cellular_cholesterol2.28947661
15MP0000609_abnormal_liver_physiology2.17700133
16MP0002118_abnormal_lipid_homeostasis2.10797982
17MP0005379_endocrine/exocrine_gland_phen2.04566549
18MP0009780_abnormal_chondrocyte_physiolo2.03425241
19MP0002138_abnormal_hepatobiliary_system2.00188443
20MP0003868_abnormal_feces_composition1.92798556
21* MP0004019_abnormal_vitamin_homeostasis1.89175534
22MP0005319_abnormal_enzyme/_coenzyme1.82025811
23MP0002909_abnormal_adrenal_gland1.71893140
24MP0001764_abnormal_homeostasis1.66171495
25MP0009697_abnormal_copulation1.62372498
26MP0005584_abnormal_enzyme/coenzyme_acti1.57090447
27MP0005451_abnormal_body_composition1.44248143
28MP0003011_delayed_dark_adaptation1.43033182
29MP0000013_abnormal_adipose_tissue1.31367284
30MP0003186_abnormal_redox_activity1.27083086
31MP0009643_abnormal_urine_homeostasis1.23887233
32MP0003656_abnormal_erythrocyte_physiolo1.22147375
33MP0000598_abnormal_liver_morphology1.18131031
34MP0010386_abnormal_urinary_bladder1.14415394
35MP0003705_abnormal_hypodermis_morpholog1.12695022
36MP0000604_amyloidosis1.11774488
37MP0005645_abnormal_hypothalamus_physiol1.09830449
38MP0005647_abnormal_sex_gland1.08912058
39MP0003879_abnormal_hair_cell1.06608571
40MP0009764_decreased_sensitivity_to1.04324601
41MP0002254_reproductive_system_inflammat1.03169997
42MP0009763_increased_sensitivity_to1.02909912
43MP0005636_abnormal_mineral_homeostasis0.92995031
44MP0010368_abnormal_lymphatic_system0.91981685
45MP0002163_abnormal_gland_morphology0.91145833
46MP0008469_abnormal_protein_level0.87985347
47MP0009642_abnormal_blood_homeostasis0.87511173
48MP0005408_hypopigmentation0.87304154
49MP0005646_abnormal_pituitary_gland0.87197576
50MP0002693_abnormal_pancreas_physiology0.86140841
51MP0005187_abnormal_penis_morphology0.82133272
52MP0006036_abnormal_mitochondrial_physio0.81926743
53MP0002078_abnormal_glucose_homeostasis0.81331727
54MP0000003_abnormal_adipose_tissue0.80292286
55MP0005084_abnormal_gallbladder_morpholo0.80197082
56MP0009765_abnormal_xenobiotic_induced0.78933336
57MP0005376_homeostasis/metabolism_phenot0.78931818
58MP0005670_abnormal_white_adipose0.76469956
59MP0005220_abnormal_exocrine_pancreas0.76327357
60MP0002876_abnormal_thyroid_physiology0.75053808
61MP0001661_extended_life_span0.73096912
62MP0002971_abnormal_brown_adipose0.73016365
63MP0005334_abnormal_fat_pad0.70455646
64MP0010234_abnormal_vibrissa_follicle0.69891661
65MP0003690_abnormal_glial_cell0.68559337
66MP0004130_abnormal_muscle_cell0.68421092
67MP0003172_abnormal_lysosome_physiology0.67488255
68MP0009053_abnormal_anal_canal0.66886644
69MP0003329_amyloid_beta_deposits0.66406784
70MP0005535_abnormal_body_temperature0.65766274
71MP0000639_abnormal_adrenal_gland0.63790807
72MP0005266_abnormal_metabolism0.63315857
73MP0001756_abnormal_urination0.60783269
74MP0005448_abnormal_energy_balance0.57708921
75MP0004270_analgesia0.56563112
76MP0006035_abnormal_mitochondrial_morpho0.55941392
77MP0002132_abnormal_respiratory_system0.53806761
78MP0005464_abnormal_platelet_physiology0.53739888
79MP0005395_other_phenotype0.49090162
80MP0001986_abnormal_taste_sensitivity0.48569115
81MP0001501_abnormal_sleep_pattern0.48244246
82MP0002928_abnormal_bile_duct0.48097322
83MP0002822_catalepsy0.47719294
84MP0003633_abnormal_nervous_system0.47316873
85MP0004043_abnormal_pH_regulation0.47307919
86MP0003638_abnormal_response/metabolism_0.46947299
87MP0002837_dystrophic_cardiac_calcinosis0.46010654
88MP0008873_increased_physiological_sensi0.45620585
89MP0002136_abnormal_kidney_physiology0.45144966
90MP0003718_maternal_effect0.44967579
91MP0008874_decreased_physiological_sensi0.44899781
92MP0003787_abnormal_imprinting0.44792413
93MP0001915_intracranial_hemorrhage0.43915548
94MP0005551_abnormal_eye_electrophysiolog0.43817560
95MP0002295_abnormal_pulmonary_circulatio0.43260790
96MP0004782_abnormal_surfactant_physiolog0.42866984
97MP0003953_abnormal_hormone_level0.42812824
98MP0005248_abnormal_Harderian_gland0.42807962
99MP0003436_decreased_susceptibility_to0.41906308
100MP0003724_increased_susceptibility_to0.39536596
101MP0003075_altered_response_to0.39438484
102MP0009672_abnormal_birth_weight0.38317788
103MP0001765_abnormal_ion_homeostasis0.37313729
104MP0005666_abnormal_adipose_tissue0.36827677
105MP0008872_abnormal_physiological_respon0.35849890
106MP0004142_abnormal_muscle_tone0.34157166
107MP0005166_decreased_susceptibility_to0.34102086
108MP0003122_maternal_imprinting0.34088303
109MP0006072_abnormal_retinal_apoptosis0.32926255
110MP0000249_abnormal_blood_vessel0.32907794
111MP0001243_abnormal_dermal_layer0.32855212
112MP0009115_abnormal_fat_cell0.32796961
113MP0002168_other_aberrant_phenotype0.32568231
114MP0004883_abnormal_blood_vessel0.31711627
115MP0005452_abnormal_adipose_tissue0.31398459
116MP0009745_abnormal_behavioral_response0.31357658
117MP0000230_abnormal_systemic_arterial0.31325352
118MP0001853_heart_inflammation0.31167161
119MP0006082_CNS_inflammation0.30741782
120MP0002970_abnormal_white_adipose0.30700830
121MP0000579_abnormal_nail_morphology0.29882256
122MP0002796_impaired_skin_barrier0.29284757
123MP0001881_abnormal_mammary_gland0.27926946
124MP0001845_abnormal_inflammatory_respons0.27785447
125MP0004381_abnormal_hair_follicle0.27448387
126MP0009384_cardiac_valve_regurgitation0.25204082
127MP0005164_abnormal_response_to0.24877766
128MP0002090_abnormal_vision0.24764536
129MP0005058_abnormal_lysosome_morphology0.24515112
130MP0001944_abnormal_pancreas_morphology0.23743666

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.52104241
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.43095617
3Intrahepatic cholestasis (HP:0001406)7.27060974
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.70579013
5Prolonged partial thromboplastin time (HP:0003645)6.60919334
6Hypobetalipoproteinemia (HP:0003563)6.58700044
7Xanthomatosis (HP:0000991)6.32235364
8Hyperlipoproteinemia (HP:0010980)5.62569568
9Complement deficiency (HP:0004431)5.20158088
10Hypolipoproteinemia (HP:0010981)4.87506901
11Joint hemorrhage (HP:0005261)4.84365066
12Hyperammonemia (HP:0001987)4.59682252
13Epidermoid cyst (HP:0200040)4.54249963
14Abnormality of the common coagulation pathway (HP:0010990)4.52507369
15Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.46439168
16Hyperglycinemia (HP:0002154)4.40895010
17Abnormality of methionine metabolism (HP:0010901)4.29716551
18Ketosis (HP:0001946)4.25863376
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.22929487
20Hypoalphalipoproteinemia (HP:0003233)4.19676168
21Abnormality of glutamine family amino acid metabolism (HP:0010902)4.15684185
22Fat malabsorption (HP:0002630)4.12807080
23Abnormality of aspartate family amino acid metabolism (HP:0010899)4.11702731
24Hypoglycemic coma (HP:0001325)3.93732610
25Hyperglycinuria (HP:0003108)3.90696539
26Abnormality of serine family amino acid metabolism (HP:0010894)3.90045619
27Abnormality of glycine metabolism (HP:0010895)3.90045619
28Abnormality of pyrimidine metabolism (HP:0004353)3.82873775
29Abnormality of the intrinsic pathway (HP:0010989)3.80815673
30Conjugated hyperbilirubinemia (HP:0002908)3.80126139
31Abnormality of complement system (HP:0005339)3.78818781
32Hypercholesterolemia (HP:0003124)3.72116348
33Hyperbilirubinemia (HP:0002904)3.38518651
34Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.34012908
35Abnormality of fatty-acid metabolism (HP:0004359)3.29713187
36Delayed CNS myelination (HP:0002188)3.10811019
37Ketoacidosis (HP:0001993)3.07052500
38Abnormality of serum amino acid levels (HP:0003112)3.06126949
39Abnormality of nucleobase metabolism (HP:0010932)3.05941635
40Steatorrhea (HP:0002570)3.05221071
41Spontaneous abortion (HP:0005268)3.01308331
42Hepatocellular carcinoma (HP:0001402)2.99114050
43Hypochromic microcytic anemia (HP:0004840)2.94002738
44Myocardial infarction (HP:0001658)2.90680521
45Skin nodule (HP:0200036)2.83602502
46Metabolic acidosis (HP:0001942)2.74670764
47Abnormality of urine glucose concentration (HP:0011016)2.74624747
48Glycosuria (HP:0003076)2.74624747
49Acanthocytosis (HP:0001927)2.67798822
50Abnormality of purine metabolism (HP:0004352)2.67475565
51Systemic lupus erythematosus (HP:0002725)2.60619151
52Vascular calcification (HP:0004934)2.60230700
53Lethargy (HP:0001254)2.59658834
54Hypoglycemic seizures (HP:0002173)2.58813501
55Glomerulonephritis (HP:0000099)2.57482843
56Abnormality of dicarboxylic acid metabolism (HP:0010995)2.55000524
57Dicarboxylic aciduria (HP:0003215)2.55000524
58Abnormal gallbladder morphology (HP:0012437)2.50152869
59Osteomalacia (HP:0002749)2.49923102
60Abnormal gallbladder physiology (HP:0012438)2.45543517
61Cholecystitis (HP:0001082)2.45543517
62Spastic diplegia (HP:0001264)2.44707011
63Fair hair (HP:0002286)2.44171327
64Gout (HP:0001997)2.43563132
65Cholelithiasis (HP:0001081)2.41599514
66Cerebral edema (HP:0002181)2.40573490
67Mitral stenosis (HP:0001718)2.40314216
68Irritability (HP:0000737)2.36659836
69Cardiovascular calcification (HP:0011915)2.30514954
70Hyperphosphaturia (HP:0003109)2.30398721
71Neonatal onset (HP:0003623)2.29550926
72Esophageal varix (HP:0002040)2.28085551
73Malnutrition (HP:0004395)2.27478816
74Amyloidosis (HP:0011034)2.27462296
75Gingival bleeding (HP:0000225)2.22030835
76Proximal tubulopathy (HP:0000114)2.21361408
77Late onset (HP:0003584)2.20435854
78Arthropathy (HP:0003040)2.19733046
79Recurrent gram-negative bacterial infections (HP:0005420)2.19361461
80Menorrhagia (HP:0000132)2.18708579
81Hyperinsulinemic hypoglycemia (HP:0000825)2.12806980
82Pancreatitis (HP:0001733)2.12695035
83Brushfield spots (HP:0001088)2.10643741
84Enlarged kidneys (HP:0000105)2.10343850
85Sensorimotor neuropathy (HP:0007141)2.09370856
86Thrombophlebitis (HP:0004418)2.07604498
87Poikilocytosis (HP:0004447)2.05563296
88Mucopolysacchariduria (HP:0008155)2.04479235
89Urinary glycosaminoglycan excretion (HP:0003541)2.04479235
90Vomiting (HP:0002013)2.03961617
91Abnormality of polysaccharide metabolism (HP:0011012)2.02032326
92Abnormality of glycosaminoglycan metabolism (HP:0004371)2.02032326
93Abnormality of mucopolysaccharide metabolism (HP:0011020)2.02032326
94Generalized aminoaciduria (HP:0002909)2.01934345
95Abnormality of the gallbladder (HP:0005264)2.01287272
96Opisthotonus (HP:0002179)1.99175960
97Hemorrhage of the eye (HP:0011885)1.97252130
98Rickets (HP:0002748)1.92281750
99Abnormal urine phosphate concentration (HP:0012599)1.89241305
100Joint swelling (HP:0001386)1.88102250
101Abnormality of iron homeostasis (HP:0011031)1.87648031
102Neonatal hypoglycemia (HP:0001998)1.87077205
103Abnormal cartilage morphology (HP:0002763)1.86853781
104Abnormality of transition element cation homeostasis (HP:0011030)1.86577000
105Abnormality of proline metabolism (HP:0010907)1.86024603
106Hydroxyprolinuria (HP:0003080)1.86024603
107Reduced antithrombin III activity (HP:0001976)1.85971711
108Purpura (HP:0000979)1.85701235
109Pulmonary embolism (HP:0002204)1.85075318
110Renal cortical cysts (HP:0000803)1.85049532
111Alkalosis (HP:0001948)1.84728057
112Hypophosphatemic rickets (HP:0004912)1.83074150
113Hypothermia (HP:0002045)1.82507786
114Increased CSF protein (HP:0002922)1.80740481
115Abnormal enzyme/coenzyme activity (HP:0012379)1.80308281
116Nephritis (HP:0000123)1.80238133
117Hyperglycemia (HP:0003074)1.79809701
118Elevated hepatic transaminases (HP:0002910)1.78928137
119Abnormality of vitamin metabolism (HP:0100508)1.77898362
120Generalized hypopigmentation of hair (HP:0011358)1.77887072
121Status epilepticus (HP:0002133)1.76230156
122Blue irides (HP:0000635)1.66251531
123Abnormality of vitamin B metabolism (HP:0004340)1.62679531
124Retinal atrophy (HP:0001105)1.60535571
125Abnormal biliary tract physiology (HP:0012439)1.52726825
126Bile duct proliferation (HP:0001408)1.52726825

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.08503834
2SIK14.64271597
3FGFR44.55249886
4ERN14.12725025
5TAOK33.23537407
6INSRR3.15963091
7NTRK32.77312159
8ERBB42.68720439
9MAP4K22.67764449
10WNK32.56062747
11PKN22.44090256
12MAP2K42.30213445
13MST42.24869564
14MAP3K122.22494809
15TRPM72.22258878
16PHKG12.20997232
17PHKG22.20997232
18MST1R2.18491651
19PIK3CG2.10755819
20FLT32.07060983
21MAP3K91.96449107
22TRIB31.80514505
23MAPK111.77766458
24LATS11.69385365
25TYK21.69228736
26ADRBK21.64167004
27FRK1.64074024
28FER1.59457703
29NLK1.57254875
30DAPK21.53931171
31PTK61.52464073
32ABL21.48082183
33TNK21.46393628
34NEK91.46210396
35FGFR21.39660055
36KDR1.32352407
37PRKCE1.24347119
38EIF2AK31.21760705
39JAK21.20221280
40MAP3K71.16336223
41PRKAA21.12985790
42CAMKK21.12197039
43PINK11.09564625
44ACVR1B1.04823996
45MAP2K31.04369510
46MYLK1.03120098
47JAK11.02649585
48MAP3K41.02326729
49STK31.01956804
50TBK11.01798573
51MAPK150.99150023
52GRK60.97898135
53MAPK40.97284506
54MAP3K100.96628483
55ERBB20.95518142
56MAP3K30.95126505
57CASK0.95020506
58MAP3K140.94832636
59PIK3CA0.94548517
60MET0.90850713
61PRKCZ0.90643901
62STK240.87278645
63STK38L0.83854500
64CAMK2D0.83485945
65PRKG10.83421706
66RIPK10.82479961
67CDK60.82204063
68EPHB10.81294588
69STK160.79645787
70EPHA30.77297652
71CAMK1D0.76821945
72PRKACG0.76139627
73DYRK1B0.75655971
74CSK0.74214740
75MAPK120.74173465
76MAP3K110.73582335
77WNK40.72520376
78TIE10.71710483
79GSK3A0.70724452
80PRKACA0.70245651
81CSNK1D0.69129060
82TAOK10.68101432
83CAMK2G0.67236977
84PRKAA10.66301590
85MAP2K60.64414840
86SGK30.62523051
87PTK20.60971662
88CSNK1A10.60232376
89IRAK30.59062525
90LMTK20.58382059
91FGFR30.57743976
92TGFBR20.57431317
93OXSR10.56874190
94MAPK70.55450688
95UHMK10.55312099
96YES10.55005088
97PRKACB0.54527845
98ERBB30.54346439
99CSF1R0.53270591
100STK40.52533180
101PTK2B0.52507598
102EIF2AK10.52105026
103MAPKAPK30.52006506
104PRKCQ0.50918666
105CSNK1G10.50079711
106PDPK10.48970961
107IKBKE0.48761684
108PRKG20.48055968
109STK110.47210609
110CSNK1E0.46509847
111SGK10.46412586
112MAP3K50.46190927
113RET0.45426348
114GRK10.45395808
115IGF1R0.45068169
116MAP2K10.44953175
117SGK20.44766650
118EPHA40.43830501
119CSNK1A1L0.43425319
120MAP3K130.42017355
121PRKCI0.41209256
122BMPR1B0.40798998
123TAOK20.40793754
124PRKCG0.40142577
125PRKCB0.39637605
126CDK40.38668818
127PNCK0.38481995
128BRSK20.37892684
129MAP3K60.37808648
130MTOR0.36796616
131AKT20.36564900
132RPS6KA30.36512811
133STK390.35749763
134PBK0.33384730
135DAPK10.33155537
136SGK4940.33049415
137SGK2230.33049415
138ARAF0.32479342
139EGFR0.32030385
140PDK10.31581255
141ICK0.31135142
142CSNK1G20.29874110
143PAK30.29670892
144CAMK40.29638897
145MAP3K10.28688908
146MAP2K20.27066480
147CAMK1G0.26778579
148MAP3K20.26699914
149IRAK10.26005172
150CSNK1G30.26002902
151PRKCA0.25802265
152PKN10.24883097
153IRAK20.22406885
154LATS20.21844829
155ABL10.20944487
156PDK30.20896362

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.42093212
2Nitrogen metabolism_Homo sapiens_hsa009103.74554562
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.42634151
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.37280744
5Arginine biosynthesis_Homo sapiens_hsa002203.08345372
6Complement and coagulation cascades_Homo sapiens_hsa046102.75708148
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.73347544
8Tryptophan metabolism_Homo sapiens_hsa003802.66017205
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.61074088
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.51670863
11Fatty acid degradation_Homo sapiens_hsa000712.47668273
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.37311975
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.29161029
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.16706187
15Butanoate metabolism_Homo sapiens_hsa006502.14392262
16Peroxisome_Homo sapiens_hsa041462.03902045
17Chemical carcinogenesis_Homo sapiens_hsa052041.97449710
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.95118913
19Steroid hormone biosynthesis_Homo sapiens_hsa001401.92727103
20Propanoate metabolism_Homo sapiens_hsa006401.92312700
21Histidine metabolism_Homo sapiens_hsa003401.91396757
22PPAR signaling pathway_Homo sapiens_hsa033201.84590765
23Fatty acid metabolism_Homo sapiens_hsa012121.80287645
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.79593710
25Staphylococcus aureus infection_Homo sapiens_hsa051501.78125284
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.76147469
27beta-Alanine metabolism_Homo sapiens_hsa004101.71624636
28Retinol metabolism_Homo sapiens_hsa008301.71540107
29Caffeine metabolism_Homo sapiens_hsa002321.69856724
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.65263928
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.60442332
32Selenocompound metabolism_Homo sapiens_hsa004501.59064275
33Phenylalanine metabolism_Homo sapiens_hsa003601.55603207
34Bile secretion_Homo sapiens_hsa049761.50096338
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50025613
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49196448
37Tyrosine metabolism_Homo sapiens_hsa003501.42337580
38Sulfur metabolism_Homo sapiens_hsa009201.36888833
39Pyruvate metabolism_Homo sapiens_hsa006201.35416276
40Fatty acid elongation_Homo sapiens_hsa000621.32043067
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.30423496
42Starch and sucrose metabolism_Homo sapiens_hsa005001.29474145
43ABC transporters_Homo sapiens_hsa020101.22371225
44Steroid biosynthesis_Homo sapiens_hsa001001.20923718
45Biosynthesis of amino acids_Homo sapiens_hsa012301.20768246
46Folate biosynthesis_Homo sapiens_hsa007901.18241343
47Fat digestion and absorption_Homo sapiens_hsa049751.18172553
48Carbon metabolism_Homo sapiens_hsa012001.12868329
49Maturity onset diabetes of the young_Homo sapiens_hsa049501.08379047
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.99482421
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.98378515
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.98020056
53Arginine and proline metabolism_Homo sapiens_hsa003300.96190913
54Sulfur relay system_Homo sapiens_hsa041220.89714353
55Vitamin B6 metabolism_Homo sapiens_hsa007500.88768085
56Vitamin digestion and absorption_Homo sapiens_hsa049770.86336206
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.84834140
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84284818
59Lysine degradation_Homo sapiens_hsa003100.81383133
60One carbon pool by folate_Homo sapiens_hsa006700.76552228
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70929822
62Glycerolipid metabolism_Homo sapiens_hsa005610.68234988
63Glutathione metabolism_Homo sapiens_hsa004800.64477287
64Pentose phosphate pathway_Homo sapiens_hsa000300.59306913
65Fatty acid biosynthesis_Homo sapiens_hsa000610.54496999
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48225547
67Metabolic pathways_Homo sapiens_hsa011000.45337094
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.38744807
69Other glycan degradation_Homo sapiens_hsa005110.36562516
70Prion diseases_Homo sapiens_hsa050200.30802723
71Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27325268
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25786562
73Insulin secretion_Homo sapiens_hsa049110.25693821
74Galactose metabolism_Homo sapiens_hsa000520.24645246
75Fructose and mannose metabolism_Homo sapiens_hsa000510.23687649
76Insulin resistance_Homo sapiens_hsa049310.23498937
77Linoleic acid metabolism_Homo sapiens_hsa005910.22583332
78Serotonergic synapse_Homo sapiens_hsa047260.22085557
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.21715856
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.20901222
81Sphingolipid metabolism_Homo sapiens_hsa006000.20372912
82Mineral absorption_Homo sapiens_hsa049780.15778065
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.15000522
84Circadian rhythm_Homo sapiens_hsa047100.13883464
85Glucagon signaling pathway_Homo sapiens_hsa049220.10339818
86Protein export_Homo sapiens_hsa030600.07736811
87AMPK signaling pathway_Homo sapiens_hsa041520.01909198
88Pertussis_Homo sapiens_hsa05133-0.2517994
89Ether lipid metabolism_Homo sapiens_hsa00565-0.2493313
90Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2386029
91Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2298244
92Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2143432
93Hepatitis C_Homo sapiens_hsa05160-0.1854429
94Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1839043
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1826650
96Renin-angiotensin system_Homo sapiens_hsa04614-0.1760513
97Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1744533
98Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1624248
99Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1610045
100Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1598061
101African trypanosomiasis_Homo sapiens_hsa05143-0.1529403
102Regulation of autophagy_Homo sapiens_hsa04140-0.1418246
103Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1391757
104Insulin signaling pathway_Homo sapiens_hsa04910-0.0955362
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0795624
106Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0770126
107Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0726858
108N-Glycan biosynthesis_Homo sapiens_hsa00510-0.0702190
109Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0513054
110Oxidative phosphorylation_Homo sapiens_hsa00190-0.0343399
111Collecting duct acid secretion_Homo sapiens_hsa04966-0.0157424

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