GCKR

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1exogenous drug catabolic process (GO:0042738)8.04168326
2L-phenylalanine catabolic process (GO:0006559)7.68994612
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.68994612
4L-phenylalanine metabolic process (GO:0006558)7.31758336
5erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.31758336
6epoxygenase P450 pathway (GO:0019373)7.30756624
7omega-hydroxylase P450 pathway (GO:0097267)7.20103072
8aromatic amino acid family catabolic process (GO:0009074)6.90440600
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.37549376
10tryptophan catabolic process (GO:0006569)6.27362276
11indole-containing compound catabolic process (GO:0042436)6.27362276
12indolalkylamine catabolic process (GO:0046218)6.27362276
13kynurenine metabolic process (GO:0070189)6.14314798
14bile acid biosynthetic process (GO:0006699)5.98902286
15tryptophan metabolic process (GO:0006568)5.89763463
16glyoxylate metabolic process (GO:0046487)5.78953601
17alpha-linolenic acid metabolic process (GO:0036109)5.70365868
18urea cycle (GO:0000050)5.67370661
19urea metabolic process (GO:0019627)5.67370661
20negative regulation of fibrinolysis (GO:0051918)5.60827528
21high-density lipoprotein particle remodeling (GO:0034375)5.56585186
22regulation of fibrinolysis (GO:0051917)5.42990348
23peptidyl-glutamic acid carboxylation (GO:0017187)5.39702839
24protein carboxylation (GO:0018214)5.39702839
25cysteine metabolic process (GO:0006534)5.38347572
26regulation of protein activation cascade (GO:2000257)5.37234929
27regulation of plasminogen activation (GO:0010755)5.35220229
28complement activation, alternative pathway (GO:0006957)5.31526202
29sulfur amino acid catabolic process (GO:0000098)5.31420066
30nitrogen cycle metabolic process (GO:0071941)5.20958491
31serine family amino acid catabolic process (GO:0009071)5.13921949
32bile acid metabolic process (GO:0008206)5.12832258
33drug metabolic process (GO:0017144)5.07490546
34oxidative demethylation (GO:0070989)5.03678032
35aromatic amino acid family metabolic process (GO:0009072)5.00272353
36intestinal cholesterol absorption (GO:0030299)5.00167420
37regulation of complement activation (GO:0030449)4.99777000
38fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.91205168
39regulation of cholesterol esterification (GO:0010872)4.86696436
40acute-phase response (GO:0006953)4.86213100
41reverse cholesterol transport (GO:0043691)4.84847466
42tyrosine metabolic process (GO:0006570)4.84704523
43regulation of triglyceride catabolic process (GO:0010896)4.80188252
44negative regulation of protein activation cascade (GO:2000258)4.80047931
45homocysteine metabolic process (GO:0050667)4.77638835
46plasma lipoprotein particle remodeling (GO:0034369)4.76766496
47protein-lipid complex remodeling (GO:0034368)4.76766496
48macromolecular complex remodeling (GO:0034367)4.76766496
49positive regulation of heterotypic cell-cell adhesion (GO:0034116)4.69454234
50alpha-amino acid catabolic process (GO:1901606)4.68388505
51negative regulation of blood coagulation (GO:0030195)4.62438399
52negative regulation of hemostasis (GO:1900047)4.62438399
53negative regulation of sterol transport (GO:0032372)4.62382913
54negative regulation of cholesterol transport (GO:0032375)4.62382913
55amino-acid betaine metabolic process (GO:0006577)4.59612284
56phospholipid efflux (GO:0033700)4.58926842
57regulation of humoral immune response (GO:0002920)4.58484334
58lysine metabolic process (GO:0006553)4.57546464
59lysine catabolic process (GO:0006554)4.57546464
60imidazole-containing compound metabolic process (GO:0052803)4.50458850
61bile acid and bile salt transport (GO:0015721)4.45930869
62coenzyme catabolic process (GO:0009109)4.44790982
63* acylglycerol homeostasis (GO:0055090)4.44713240
64* triglyceride homeostasis (GO:0070328)4.44713240
65cellular ketone body metabolic process (GO:0046950)4.44541538
66indolalkylamine metabolic process (GO:0006586)4.43966109
67glycine metabolic process (GO:0006544)4.43827815
68ethanol metabolic process (GO:0006067)4.43809291
69plasma lipoprotein particle clearance (GO:0034381)4.37112399
70cellular biogenic amine catabolic process (GO:0042402)4.36451380
71amine catabolic process (GO:0009310)4.36451380
72glutamate metabolic process (GO:0006536)4.32984266
73cellular amino acid catabolic process (GO:0009063)4.28985795
74negative regulation of coagulation (GO:0050819)4.26712139
75cholesterol efflux (GO:0033344)4.25895422
76cellular glucuronidation (GO:0052695)4.24202614
77serine family amino acid metabolic process (GO:0009069)4.18353904
78benzene-containing compound metabolic process (GO:0042537)4.16669883
79ethanol oxidation (GO:0006069)4.13580596
80negative regulation of wound healing (GO:0061045)4.12943125
81dicarboxylic acid biosynthetic process (GO:0043650)4.09304339
82cellular modified amino acid catabolic process (GO:0042219)4.08352794
83positive regulation of blood coagulation (GO:0030194)4.06785808
84positive regulation of hemostasis (GO:1900048)4.06785808
85low-density lipoprotein particle remodeling (GO:0034374)4.04235619
86serine family amino acid biosynthetic process (GO:0009070)4.03231210
87plasma lipoprotein particle assembly (GO:0034377)4.01002531
88arginine metabolic process (GO:0006525)4.00999391
89fibrinolysis (GO:0042730)4.00303977
90aldehyde catabolic process (GO:0046185)4.00185348
91regulation of apoptotic cell clearance (GO:2000425)3.99687188
92drug catabolic process (GO:0042737)3.97354334
93S-adenosylmethionine metabolic process (GO:0046500)3.91392456
94alkaloid metabolic process (GO:0009820)3.89400144
95regulation of bile acid biosynthetic process (GO:0070857)3.86505747
96killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.86118346
97disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.86118346
98negative regulation of complement activation (GO:0045916)3.86105395
99ketone body metabolic process (GO:1902224)3.84611266
100blood coagulation, intrinsic pathway (GO:0007597)3.83940297
101protein-lipid complex subunit organization (GO:0071825)3.83087998
102very-low-density lipoprotein particle assembly (GO:0034379)3.80869984
103cofactor catabolic process (GO:0051187)3.80599883
104phenylpropanoid metabolic process (GO:0009698)3.79728725
105complement activation, classical pathway (GO:0006958)3.79439684
106regulation of cholesterol homeostasis (GO:2000188)3.78714041
107positive regulation of lipoprotein lipase activity (GO:0051006)3.77336869
108positive regulation of triglyceride lipase activity (GO:0061365)3.77336869
109phospholipid homeostasis (GO:0055091)3.76103316
110positive regulation of coagulation (GO:0050820)3.75453673
111uronic acid metabolic process (GO:0006063)3.75166227
112glucuronate metabolic process (GO:0019585)3.75166227
113positive regulation of lipid catabolic process (GO:0050996)3.74336740
114complement activation (GO:0006956)3.74272042
115carboxylic acid catabolic process (GO:0046395)3.73900805
116organic acid catabolic process (GO:0016054)3.73900805
117cholesterol homeostasis (GO:0042632)3.73306053
118negative regulation of lipase activity (GO:0060192)3.73169933
119protein activation cascade (GO:0072376)3.72920024
120acetyl-CoA metabolic process (GO:0006084)3.68833332
121sterol homeostasis (GO:0055092)3.67032131
122short-chain fatty acid metabolic process (GO:0046459)3.64600040
123acute inflammatory response (GO:0002526)3.64329631
124cytolysis (GO:0019835)3.63239110
125plasma lipoprotein particle organization (GO:0071827)3.62959004
126flavonoid metabolic process (GO:0009812)3.61914859
127opsonization (GO:0008228)3.61843867
128protein-lipid complex assembly (GO:0065005)3.59942002
129NAD biosynthetic process (GO:0009435)3.58535767
130sodium-independent organic anion transport (GO:0043252)3.52788888
131positive regulation of fatty acid biosynthetic process (GO:0045723)3.52356574

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.42577090
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.22925500
3EGR1_23403033_ChIP-Seq_LIVER_Mouse7.02962906
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.52139451
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.32573054
6* CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.01068432
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.69673160
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.09521569
9* CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.89532822
10TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.06964150
11ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.9872828
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.93224831
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.92299694
14FOXA2_19822575_ChIP-Seq_HepG2_Human1.62948132
15HTT_18923047_ChIP-ChIP_STHdh_Human1.60302022
16CLOCK_20551151_ChIP-Seq_293T_Human1.52454516
17HNF4A_19822575_ChIP-Seq_HepG2_Human1.41750845
18GATA1_22025678_ChIP-Seq_K562_Human1.35715280
19THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.29270524
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.21434209
21RXRA_24833708_ChIP-Seq_LIVER_Mouse1.20637003
22STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.16372602
23CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.15112528
24FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.14775222
25GBX2_23144817_ChIP-Seq_PC3_Human1.10731714
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.06791158
27GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04540650
28ESR1_15608294_ChIP-ChIP_MCF-7_Human1.03591730
29IGF1R_20145208_ChIP-Seq_DFB_Human1.03089749
30PCGF2_27294783_Chip-Seq_NPCs_Mouse1.01963598
31PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01036903
32IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00069965
33ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99994979
34EZH2_27294783_Chip-Seq_NPCs_Mouse0.97566703
35TP53_16413492_ChIP-PET_HCT116_Human0.97520585
36PIAS1_25552417_ChIP-Seq_VCAP_Human0.96063894
37SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92890888
38NANOG_19829295_ChIP-Seq_ESCs_Human0.91763845
39SOX2_19829295_ChIP-Seq_ESCs_Human0.91763845
40TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.90432355
41SOX2_27498859_Chip-Seq_STOMACH_Mouse0.89621566
42MYC_19829295_ChIP-Seq_ESCs_Human0.89470438
43ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88061536
44POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87420682
45AUTS2_25519132_ChIP-Seq_293T-REX_Human0.85455895
46CRX_20693478_ChIP-Seq_RETINA_Mouse0.84885980
47PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.83764068
48ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.83162439
49ER_23166858_ChIP-Seq_MCF-7_Human0.81625780
50PCGF2_27294783_Chip-Seq_ESCs_Mouse0.80919757
51KLF5_20875108_ChIP-Seq_MESCs_Mouse0.80613653
52* KAP1_22055183_ChIP-Seq_ESCs_Mouse0.79144142
53ZNF274_21170338_ChIP-Seq_K562_Hela0.78870575
54IRF8_22096565_ChIP-ChIP_GC-B_Human0.78617943
55GATA4_25053715_ChIP-Seq_YYC3_Human0.78467968
56RARG_19884340_ChIP-ChIP_MEFs_Mouse0.78246002
57BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.76620592
58SMAD1_18555785_Chip-Seq_ESCs_Mouse0.76390869
59SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.75856288
60RAC3_21632823_ChIP-Seq_H3396_Human0.75759873
61ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.75405019
62OCT4_21477851_ChIP-Seq_ESCs_Mouse0.74494990
63SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.74016372
64ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.73450896
65RARA_24833708_ChIP-Seq_LIVER_Mouse0.73329068
66* SMAD4_21741376_ChIP-Seq_EPCs_Human0.72659240
67Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.72655846
68TCF4_18268006_ChIP-ChIP_LS174T_Human0.72253465
69FLI1_27457419_Chip-Seq_LIVER_Mouse0.70765302
70GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.70732360
71CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.70058795
72EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.69345541
73LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.69123529
74FOXH1_21741376_ChIP-Seq_ESCs_Human0.68614282
75UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.68451521
76IRF1_19129219_ChIP-ChIP_H3396_Human0.68154609
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.68030146
78TP53_18474530_ChIP-ChIP_U2OS_Human0.67794898
79AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.67658631
80ZNF263_19887448_ChIP-Seq_K562_Human0.67654632
81SALL4_18804426_ChIP-ChIP_XEN_Mouse0.67569196
82SOX2_20726797_ChIP-Seq_SW620_Human0.67271460
83ESRRB_18555785_Chip-Seq_ESCs_Mouse0.66972961
84OCT4_18555785_Chip-Seq_ESCs_Mouse0.66875939
85RUNX1_27457419_Chip-Seq_LIVER_Mouse0.66687137
86EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.66305402
87HNFA_21074721_ChIP-Seq_CACO-2_Human0.66176155
88TCF4_22108803_ChIP-Seq_LS180_Human0.64945109
89NRF2_20460467_ChIP-Seq_MEFs_Mouse0.64294214
90NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.64294214
91NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.64078588
92ESR2_21235772_ChIP-Seq_MCF-7_Human0.63796515
93RARB_24833708_ChIP-Seq_LIVER_Mouse0.63297639
94RAD21_21589869_ChIP-Seq_MESCs_Mouse0.59999645
95BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.59100097
96RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.57726057
97CEBPB_22108803_ChIP-Seq_LS180_Human0.57664536
98NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.57654734
99E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.56025090
100NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.55398811
101PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.54905616
102FOXA1_25552417_ChIP-Seq_VCAP_Human0.54455256
103FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.52879015
104AR_20517297_ChIP-Seq_VCAP_Human0.52848860
105EGR1_19032775_ChIP-ChIP_M12_Human0.52769425
106TAF15_26573619_Chip-Seq_HEK293_Human0.51324559
107MYC_19915707_ChIP-ChIP_AK7_Human0.50786347
108STAT1_17558387_ChIP-Seq_HELA_Human0.50763076
109CBP_21632823_ChIP-Seq_H3396_Human0.50737708
110* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.50284737
111ESET_19884257_ChIP-Seq_ESCs_Mouse0.49730618
112* LXR_22292898_ChIP-Seq_THP-1_Human0.48729782
113P53_21459846_ChIP-Seq_SAOS-2_Human0.48370031
114STAT3_1855785_ChIP-Seq_MESCs_Mouse0.46406329
115PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.45990273
116ESR1_20079471_ChIP-ChIP_T-47D_Human0.44131976
117CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.43462957
118PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.43059372
119FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.42645286
120FOXO3_23340844_ChIP-Seq_DLD1_Human0.42315847
121GATA1_19941827_ChIP-Seq_MEL_Mouse0.42291032
122BCAT_22108803_ChIP-Seq_LS180_Human0.41921182
123TAF2_19829295_ChIP-Seq_ESCs_Human0.41616142
124GATA1_19941826_ChIP-Seq_K562_Human0.40985524
125PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.40343786
126MYC_27129775_Chip-Seq_CORNEA_Mouse0.39837382
127ESR1_21235772_ChIP-Seq_MCF-7_Human0.39158633
128CDX2_20551321_ChIP-Seq_CACO-2_Human0.38952924
129* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.38920979
130GATA2_19941826_ChIP-Seq_K562_Human0.38443350
131PPAR_26484153_Chip-Seq_NCI-H1993_Human0.38353961
132GATA6_25053715_ChIP-Seq_YYC3_Human0.38300620
133ERG_21242973_ChIP-ChIP_JURKAT_Human0.38178942
134SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.38170424
135LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.37080100
136GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.36257184
137SPI1_26923725_Chip-Seq_HPCs_Mouse0.35908723
138NCOR_22424771_ChIP-Seq_293T_Human0.35694964
139FOXH1_21741376_ChIP-Seq_EPCs_Human0.35066059
140* STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.34638346
141CDX2_22108803_ChIP-Seq_LS180_Human0.34152356
142OCT4_20526341_ChIP-Seq_ESCs_Human0.33977896
143ERG_20517297_ChIP-Seq_VCAP_Human0.32367163

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.34772200
2MP0005360_urolithiasis7.51012815
3MP0005085_abnormal_gallbladder_physiolo6.46973977
4MP0005365_abnormal_bile_salt6.19419392
5MP0008875_abnormal_xenobiotic_pharmacok5.18322596
6MP0003806_abnormal_nucleotide_metabolis4.27493683
7MP0003252_abnormal_bile_duct3.96788963
8MP0010329_abnormal_lipoprotein_level3.60670590
9MP0009840_abnormal_foam_cell3.28530472
10MP0005083_abnormal_biliary_tract3.10410850
11MP0003195_calcinosis2.88032319
12MP0005332_abnormal_amino_acid2.72609272
13MP0001666_abnormal_nutrient_absorption2.59604083
14MP0003191_abnormal_cellular_cholesterol2.26278598
15MP0000609_abnormal_liver_physiology2.17730846
16MP0004019_abnormal_vitamin_homeostasis2.13428941
17MP0002118_abnormal_lipid_homeostasis2.11014174
18MP0002138_abnormal_hepatobiliary_system1.92139867
19MP0003868_abnormal_feces_composition1.89137553
20MP0005319_abnormal_enzyme/_coenzyme1.82070633
21MP0001764_abnormal_homeostasis1.68796592
22MP0009697_abnormal_copulation1.61173337
23MP0003011_delayed_dark_adaptation1.58877260
24MP0005451_abnormal_body_composition1.49872227
25* MP0005584_abnormal_enzyme/coenzyme_acti1.46849356
26MP0003656_abnormal_erythrocyte_physiolo1.25785867
27MP0003186_abnormal_redox_activity1.21729889
28MP0009643_abnormal_urine_homeostasis1.18414666
29MP0000598_abnormal_liver_morphology1.16854445
30MP0005647_abnormal_sex_gland1.15687435
31MP0003705_abnormal_hypodermis_morpholog1.12664339
32MP0000604_amyloidosis1.07913514
33MP0009764_decreased_sensitivity_to1.06272763
34MP0009763_increased_sensitivity_to1.02534729
35MP0002254_reproductive_system_inflammat1.02369009
36MP0010368_abnormal_lymphatic_system1.02364758
37MP0003122_maternal_imprinting0.97073596
38MP0003879_abnormal_hair_cell0.97012944
39MP0005167_abnormal_blood-brain_barrier0.90664160
40MP0005636_abnormal_mineral_homeostasis0.89240441
41MP0008469_abnormal_protein_level0.86791365
42MP0000566_synostosis0.86261308
43* MP0009642_abnormal_blood_homeostasis0.85266907
44MP0005408_hypopigmentation0.84401010
45MP0001915_intracranial_hemorrhage0.83653100
46MP0006036_abnormal_mitochondrial_physio0.79927882
47MP0005376_homeostasis/metabolism_phenot0.79850261
48MP0005058_abnormal_lysosome_morphology0.79649502
49MP0005084_abnormal_gallbladder_morpholo0.79069829
50MP0009765_abnormal_xenobiotic_induced0.77950917
51MP0005670_abnormal_white_adipose0.77211187
52* MP0002078_abnormal_glucose_homeostasis0.75210534
53MP0002876_abnormal_thyroid_physiology0.74398689
54MP0002971_abnormal_brown_adipose0.73971760
55MP0005220_abnormal_exocrine_pancreas0.73646920
56MP0005334_abnormal_fat_pad0.71003097
57MP0001661_extended_life_span0.67921569
58MP0002282_abnormal_trachea_morphology0.67274791
59MP0003172_abnormal_lysosome_physiology0.66683469
60MP0002089_abnormal_postnatal_growth/wei0.66604060
61MP0005535_abnormal_body_temperature0.66558535
62MP0005266_abnormal_metabolism0.65619172
63MP0009785_altered_susceptibility_to0.65610611
64MP0003690_abnormal_glial_cell0.65572716
65MP0004130_abnormal_muscle_cell0.65504275
66MP0006054_spinal_hemorrhage0.64448646
67MP0003329_amyloid_beta_deposits0.63381155
68MP0009053_abnormal_anal_canal0.61568427
69MP0000639_abnormal_adrenal_gland0.60522117
70MP0006035_abnormal_mitochondrial_morpho0.59559885
71MP0005379_endocrine/exocrine_gland_phen0.59041012
72MP0001756_abnormal_urination0.55828893
73MP0005448_abnormal_energy_balance0.55483708
74MP0004043_abnormal_pH_regulation0.54513165
75MP0003950_abnormal_plasma_membrane0.54511892
76MP0005464_abnormal_platelet_physiology0.53427868
77MP0003718_maternal_effect0.51355854
78MP0005395_other_phenotype0.50946126
79MP0002822_catalepsy0.49574219
80MP0002928_abnormal_bile_duct0.48917136
81MP0004782_abnormal_surfactant_physiolog0.48466030
82MP0005164_abnormal_response_to0.47313096
83MP0006292_abnormal_olfactory_placode0.46329654
84MP0008874_decreased_physiological_sensi0.46052981
85MP0008873_increased_physiological_sensi0.43814481
86MP0003638_abnormal_response/metabolism_0.43517193
87MP0003436_decreased_susceptibility_to0.43406569
88MP0003878_abnormal_ear_physiology0.43165193
89MP0005377_hearing/vestibular/ear_phenot0.43165193
90MP0002136_abnormal_kidney_physiology0.42736322
91MP0005248_abnormal_Harderian_gland0.42590593
92MP0003724_increased_susceptibility_to0.41867933
93MP0002837_dystrophic_cardiac_calcinosis0.40903231
94MP0005410_abnormal_fertilization0.40808081
95MP0003075_altered_response_to0.39723575
96* MP0003953_abnormal_hormone_level0.38660077
97MP0004381_abnormal_hair_follicle0.38057695
98MP0005166_decreased_susceptibility_to0.37774114
99MP0000579_abnormal_nail_morphology0.37377341
100MP0008872_abnormal_physiological_respon0.37223030
101MP0002090_abnormal_vision0.35862460
102MP0009672_abnormal_birth_weight0.35581203
103MP0005666_abnormal_adipose_tissue0.34630055
104MP0005187_abnormal_penis_morphology0.34228510
105MP0000371_diluted_coat_color0.33835834
106MP0005023_abnormal_wound_healing0.33414327
107MP0006082_CNS_inflammation0.33078037
108MP0003633_abnormal_nervous_system0.32452898
109MP0009115_abnormal_fat_cell0.31748479
110MP0002168_other_aberrant_phenotype0.31634300
111MP0002933_joint_inflammation0.31355108
112MP0000230_abnormal_systemic_arterial0.31324532
113MP0002909_abnormal_adrenal_gland0.31120263
114MP0009384_cardiac_valve_regurgitation0.30645937
115MP0002796_impaired_skin_barrier0.30515481
116MP0002970_abnormal_white_adipose0.30483049
117MP0001243_abnormal_dermal_layer0.30345791
118MP0000249_abnormal_blood_vessel0.30031297
119MP0004883_abnormal_blood_vessel0.28277980
120MP0001881_abnormal_mammary_gland0.27929996
121MP0001853_heart_inflammation0.27839471
122MP0003183_abnormal_peptide_metabolism0.26482703
123MP0001324_abnormal_eye_pigmentation0.26404206
124MP0001845_abnormal_inflammatory_respons0.25747255
125MP0005551_abnormal_eye_electrophysiolog0.24199093
126MP0002132_abnormal_respiratory_system0.23757383

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.48262098
2Deep venous thrombosis (HP:0002625)7.47692314
3Intrahepatic cholestasis (HP:0001406)7.36296202
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.69949844
5Prolonged partial thromboplastin time (HP:0003645)6.62319519
6Hypobetalipoproteinemia (HP:0003563)6.46787109
7Xanthomatosis (HP:0000991)6.29491326
8Hyperlipoproteinemia (HP:0010980)5.62528135
9Complement deficiency (HP:0004431)5.34559553
10Joint hemorrhage (HP:0005261)4.82737694
11Hypolipoproteinemia (HP:0010981)4.80940410
12Hyperammonemia (HP:0001987)4.56552708
13Epidermoid cyst (HP:0200040)4.55164563
14Abnormality of the common coagulation pathway (HP:0010990)4.52359911
15Hyperglycinemia (HP:0002154)4.45229372
16Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.39504756
17Abnormality of methionine metabolism (HP:0010901)4.26391597
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.23678379
19Ketosis (HP:0001946)4.22353168
20Hypoalphalipoproteinemia (HP:0003233)4.19736791
21Fat malabsorption (HP:0002630)4.14466549
22Abnormality of aspartate family amino acid metabolism (HP:0010899)4.08021774
23Abnormality of glutamine family amino acid metabolism (HP:0010902)4.07712962
24Abnormality of glycine metabolism (HP:0010895)3.90164967
25Abnormality of serine family amino acid metabolism (HP:0010894)3.90164967
26Hyperglycinuria (HP:0003108)3.89239026
27Abnormality of complement system (HP:0005339)3.88676909
28Hypoglycemic coma (HP:0001325)3.87221634
29Conjugated hyperbilirubinemia (HP:0002908)3.83871486
30Abnormality of pyrimidine metabolism (HP:0004353)3.78500220
31Abnormality of the intrinsic pathway (HP:0010989)3.77004544
32Hypercholesterolemia (HP:0003124)3.67282194
33Hyperbilirubinemia (HP:0002904)3.36164062
34Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.35278690
35Abnormality of fatty-acid metabolism (HP:0004359)3.29812916
36Spontaneous abortion (HP:0005268)3.17086283
37Steatorrhea (HP:0002570)3.11896507
38Purpura (HP:0000979)3.11482073
39Delayed CNS myelination (HP:0002188)3.09007010
40Myocardial infarction (HP:0001658)3.06237328
41Abnormality of serum amino acid levels (HP:0003112)3.05127599
42Abnormality of nucleobase metabolism (HP:0010932)3.02638776
43Hypochromic microcytic anemia (HP:0004840)3.01405217
44Ketoacidosis (HP:0001993)2.98694675
45Hepatocellular carcinoma (HP:0001402)2.98447842
46Skin nodule (HP:0200036)2.81399102
47Metabolic acidosis (HP:0001942)2.72429288
48Systemic lupus erythematosus (HP:0002725)2.71240985
49Abnormality of purine metabolism (HP:0004352)2.64708054
50Vascular calcification (HP:0004934)2.64260147
51Acanthocytosis (HP:0001927)2.57511920
52Lethargy (HP:0001254)2.55029733
53Mitral stenosis (HP:0001718)2.54363551
54Abnormal gallbladder morphology (HP:0012437)2.53845663
55Hypoglycemic seizures (HP:0002173)2.53571526
56Abnormality of dicarboxylic acid metabolism (HP:0010995)2.52542351
57Dicarboxylic aciduria (HP:0003215)2.52542351
58Fair hair (HP:0002286)2.51847189
59Cholecystitis (HP:0001082)2.49491059
60Abnormal gallbladder physiology (HP:0012438)2.49491059
61Cholelithiasis (HP:0001081)2.47697960
62Arthropathy (HP:0003040)2.46184594
63Glomerulonephritis (HP:0000099)2.44210197
64Spastic diplegia (HP:0001264)2.43047396
65Gout (HP:0001997)2.39797982
66Cardiovascular calcification (HP:0011915)2.34034414
67Malnutrition (HP:0004395)2.33355592
68Cerebral edema (HP:0002181)2.33183758
69Irritability (HP:0000737)2.32419137
70Amyloidosis (HP:0011034)2.31779758
71Neonatal onset (HP:0003623)2.30593548
72Recurrent gram-negative bacterial infections (HP:0005420)2.28489713
73Pulmonary embolism (HP:0002204)2.26281139
74Gingival bleeding (HP:0000225)2.26021804
75Joint swelling (HP:0001386)2.21450087
76Osteomalacia (HP:0002749)2.21229792
77Esophageal varix (HP:0002040)2.20202774
78Brushfield spots (HP:0001088)2.15187157
79Sensorimotor neuropathy (HP:0007141)2.14530239
80Menorrhagia (HP:0000132)2.13575285
81Late onset (HP:0003584)2.12978849
82Thrombophlebitis (HP:0004418)2.11812922
83Pancreatitis (HP:0001733)2.10286342
84Enlarged kidneys (HP:0000105)2.09862189
85Hemorrhage of the eye (HP:0011885)2.06565874
86Poikilocytosis (HP:0004447)2.06423739
87Glycosuria (HP:0003076)2.04977165
88Abnormality of urine glucose concentration (HP:0011016)2.04977165
89Abnormality of the gallbladder (HP:0005264)2.04561913
90Hyperinsulinemic hypoglycemia (HP:0000825)2.03928469
91Opisthotonus (HP:0002179)2.03694426
92Vomiting (HP:0002013)2.02026022
93Gangrene (HP:0100758)1.99076735
94Generalized aminoaciduria (HP:0002909)1.96672093
95Rickets (HP:0002748)1.95093521
96Abnormality of iron homeostasis (HP:0011031)1.92447914
97Epistaxis (HP:0000421)1.92078341
98Hypophosphatemic rickets (HP:0004912)1.91947339
99Increased serum ferritin (HP:0003281)1.89865152
100Abnormality of transition element cation homeostasis (HP:0011030)1.89475010
101Renal cortical cysts (HP:0000803)1.86068189
102Abnormal cartilage morphology (HP:0002763)1.83154104
103Hydroxyprolinuria (HP:0003080)1.82161823
104Abnormality of proline metabolism (HP:0010907)1.82161823
105Status epilepticus (HP:0002133)1.81389303
106Elevated hepatic transaminases (HP:0002910)1.80651662
107Retinal atrophy (HP:0001105)1.80003462
108Abnormal biliary tract physiology (HP:0012439)1.78222822
109Bile duct proliferation (HP:0001408)1.78222822
110Abnormal enzyme/coenzyme activity (HP:0012379)1.78055654
111Cerebral palsy (HP:0100021)1.77825977
112Abnormality of vitamin metabolism (HP:0100508)1.77793344
113Alkalosis (HP:0001948)1.75134194
114Hyperglycemia (HP:0003074)1.74882898
115Hyperphosphaturia (HP:0003109)1.74651961
116Reticulocytosis (HP:0001923)1.72727490
117Nephritis (HP:0000123)1.72379145
118Potter facies (HP:0002009)1.71480105
119Facial shape deformation (HP:0011334)1.71480105
120Generalized hypopigmentation of hair (HP:0011358)1.66443648
121Bifid scrotum (HP:0000048)1.63891843
122Hypothermia (HP:0002045)1.61750712
123Azoospermia (HP:0000027)1.61231211
124Reduced antithrombin III activity (HP:0001976)1.60488181
125Increased mean platelet volume (HP:0011877)1.59621636
126Abnormal tarsal ossification (HP:0008369)1.57029581
127Abnormality of the Achilles tendon (HP:0005109)1.54820574
128Abnormality of alkaline phosphatase activity (HP:0004379)1.51238453
129Increased serum pyruvate (HP:0003542)1.50892843
130Retrobulbar optic neuritis (HP:0100654)1.48388195
131Optic neuritis (HP:0100653)1.48388195
132Elevated alkaline phosphatase (HP:0003155)1.47399421

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.90006529
2SIK14.66117610
3FGFR44.63891884
4ERN14.38015244
5WNK43.91864483
6TAOK33.36802662
7INSRR3.13210540
8ERBB43.04374294
9BRSK22.87023269
10MAP2K42.32964099
11NTRK32.28181429
12PKN22.21718374
13PIK3CA2.12136834
14ACVR1B2.10263956
15PDK22.08901976
16MST1R2.00400940
17FLT31.90974615
18MAPK111.89025390
19CASK1.85817252
20LATS11.84452321
21PIK3CG1.83261310
22MAP4K21.75669739
23TYK21.73744525
24TRIB31.60242677
25DAPK21.59776240
26ADRBK21.51254987
27BMPR1B1.46199191
28PTK61.44555249
29ABL21.42510150
30NEK91.40330274
31FGFR21.33711188
32TYRO31.32619656
33FRK1.31389619
34DDR21.28946453
35NLK1.28657160
36WNK31.28292176
37CAMKK21.26517741
38PINK11.25329905
39STK391.23774491
40MAP3K71.23245233
41JAK21.22987517
42KDR1.22957506
43TNIK1.22915007
44PRKAA21.17321891
45FER1.15628228
46TRIM281.14034845
47MATK1.13568724
48ERBB21.07308258
49JAK11.04072504
50MAP3K141.03135917
51LMTK21.01814410
52TBK10.99489024
53MAPK150.98314066
54STK38L0.95592499
55PRKCZ0.94852390
56MAP2K30.94395814
57MAPK40.94289844
58FGFR10.94257793
59GRK60.91891434
60MAP3K100.91073569
61STK160.89383244
62CAMK1D0.85203437
63IKBKB0.85108532
64GRK70.84841156
65MAPKAPK30.80749130
66MAPK120.80692926
67EPHA30.79363537
68MET0.78082540
69FGR0.78048928
70CDK60.77815006
71EPHB10.77161461
72PRKACG0.75780161
73EIF2AK10.75434976
74PRKAA10.74021136
75GRK10.73388452
76DYRK1B0.71439972
77MAP3K30.71100677
78TIE10.70579434
79CAMK2G0.69492360
80SGK30.69183133
81CSK0.68450459
82RIPK10.66537224
83MAP3K110.65916099
84PNCK0.63615427
85MAP3K130.63499311
86GSK3A0.62739997
87MAP2K60.61240797
88PRKACA0.61236968
89MAPK70.61191279
90IRAK30.60115385
91PRKG10.60031623
92MAP3K120.59797065
93CSNK1D0.57446963
94EPHA40.57211276
95CHUK0.56980530
96WEE10.56808200
97MAPKAPK50.55368327
98SGK20.54970133
99FGFR30.54796531
100PTK20.54033255
101IKBKE0.53455936
102MAP3K60.52933054
103CSF1R0.52663751
104MAP3K20.51262463
105TGFBR20.51133556
106BCR0.51111479
107SGK10.49654510
108CSNK1G10.49397301
109PRKCQ0.48814112
110PDPK10.47754169
111CSNK1E0.47140090
112TXK0.46918331
113PBK0.46841686
114ICK0.45917299
115TAOK20.45806556
116BRSK10.43083820
117IGF1R0.41995343
118MAP3K50.41665839
119RET0.41484692
120PRKCG0.40278055
121PKN10.40110942
122CDK40.39485800
123SGK4940.38856176
124SGK2230.38856176
125MAP2K10.38771174
126CAMK1G0.37267409
127STK30.37032233
128PDGFRA0.36657443
129MTOR0.36545571
130LATS20.35250136
131IRAK20.33216674
132PRKCE0.33029373
133CDC42BPA0.32168957
134CAMK40.31548060
135MELK0.30829841
136CSNK1A10.30698438
137CSNK1G20.30528441
138EGFR0.29385796
139PDK10.29150541
140MAP3K10.28288237
141PRKCA0.26389700
142CSNK1G30.25586958
143IRAK10.24762915
144ABL10.22123476
145AKT30.21280039
146PAK30.20676182
147CSNK1A1L0.20569700
148MAPK30.18280311

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.53627244
2Nitrogen metabolism_Homo sapiens_hsa009103.60190507
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.39369246
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.36382999
5Arginine biosynthesis_Homo sapiens_hsa002203.06635532
6Complement and coagulation cascades_Homo sapiens_hsa046102.78103365
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.73195070
8Tryptophan metabolism_Homo sapiens_hsa003802.70327902
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.61120863
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.54820579
11Fatty acid degradation_Homo sapiens_hsa000712.47537049
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.36268313
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.24568952
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.14283613
15Butanoate metabolism_Homo sapiens_hsa006502.13812386
16Peroxisome_Homo sapiens_hsa041462.07546905
17Chemical carcinogenesis_Homo sapiens_hsa052041.96503346
18Histidine metabolism_Homo sapiens_hsa003401.93517296
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.92860613
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.92760123
21Propanoate metabolism_Homo sapiens_hsa006401.89622084
22PPAR signaling pathway_Homo sapiens_hsa033201.85723784
23Fatty acid metabolism_Homo sapiens_hsa012121.79878226
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.78679309
25Staphylococcus aureus infection_Homo sapiens_hsa051501.78633507
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.75653656
27Caffeine metabolism_Homo sapiens_hsa002321.75529429
28Retinol metabolism_Homo sapiens_hsa008301.74256592
29beta-Alanine metabolism_Homo sapiens_hsa004101.69742749
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.66181147
31Selenocompound metabolism_Homo sapiens_hsa004501.59241892
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.58055119
33Phenylalanine metabolism_Homo sapiens_hsa003601.55713070
34Bile secretion_Homo sapiens_hsa049761.50575176
352-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49726710
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.49039707
37Tyrosine metabolism_Homo sapiens_hsa003501.46111549
38Pyruvate metabolism_Homo sapiens_hsa006201.35201423
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.32281905
40Fatty acid elongation_Homo sapiens_hsa000621.31369013
41Sulfur metabolism_Homo sapiens_hsa009201.28262951
42Starch and sucrose metabolism_Homo sapiens_hsa005001.27586824
43ABC transporters_Homo sapiens_hsa020101.24400003
44Folate biosynthesis_Homo sapiens_hsa007901.20789890
45Biosynthesis of amino acids_Homo sapiens_hsa012301.20546893
46Steroid biosynthesis_Homo sapiens_hsa001001.20546735
47Fat digestion and absorption_Homo sapiens_hsa049751.15130022
48Carbon metabolism_Homo sapiens_hsa012001.11379405
49Maturity onset diabetes of the young_Homo sapiens_hsa049501.02696964
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01875326
51Vitamin B6 metabolism_Homo sapiens_hsa007501.00337365
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.97329055
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.96388022
54Arginine and proline metabolism_Homo sapiens_hsa003300.96037787
55Sulfur relay system_Homo sapiens_hsa041220.91744499
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.85951953
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.85478816
58Vitamin digestion and absorption_Homo sapiens_hsa049770.84156816
59Lysine degradation_Homo sapiens_hsa003100.83222416
60One carbon pool by folate_Homo sapiens_hsa006700.77626887
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71416178
62Glycerolipid metabolism_Homo sapiens_hsa005610.67614742
63Glutathione metabolism_Homo sapiens_hsa004800.62410443
64Pentose phosphate pathway_Homo sapiens_hsa000300.56893132
65Fatty acid biosynthesis_Homo sapiens_hsa000610.54691167
66Pertussis_Homo sapiens_hsa051330.49145931
67Metabolic pathways_Homo sapiens_hsa011000.45238329
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44723504
69Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42816190
70Other glycan degradation_Homo sapiens_hsa005110.36718590
71Prion diseases_Homo sapiens_hsa050200.33945852
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27971720
73Galactose metabolism_Homo sapiens_hsa000520.27020429
74Fructose and mannose metabolism_Homo sapiens_hsa000510.25059924
75Insulin resistance_Homo sapiens_hsa049310.23406655
76Linoleic acid metabolism_Homo sapiens_hsa005910.22967670
77Mineral absorption_Homo sapiens_hsa049780.21977599
78Adipocytokine signaling pathway_Homo sapiens_hsa049200.21846823
79Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.18183507
80Glycerophospholipid metabolism_Homo sapiens_hsa005640.17775862
81Glucagon signaling pathway_Homo sapiens_hsa049220.10913670
82Sphingolipid metabolism_Homo sapiens_hsa006000.06468240
83AMPK signaling pathway_Homo sapiens_hsa041520.02337454
84Ether lipid metabolism_Homo sapiens_hsa005650.02139371
85Bladder cancer_Homo sapiens_hsa05219-0.2361843
86Circadian rhythm_Homo sapiens_hsa04710-0.2349959
87Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2331958
88Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2296223
89Renin-angiotensin system_Homo sapiens_hsa04614-0.2272004
90Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2270245
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2159103
92Thyroid hormone synthesis_Homo sapiens_hsa04918-0.2021030
93Hepatitis C_Homo sapiens_hsa05160-0.1840926
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1822711
95Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1804446
96Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1603234
97Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1601166
98African trypanosomiasis_Homo sapiens_hsa05143-0.1503029
99Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1398545
100Regulation of autophagy_Homo sapiens_hsa04140-0.1338036
101Amoebiasis_Homo sapiens_hsa05146-0.1278739
102Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060-0.1003187
103Insulin signaling pathway_Homo sapiens_hsa04910-0.0993873
104Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0969198
105N-Glycan biosynthesis_Homo sapiens_hsa00510-0.0765100
106Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0763530
107Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0598876
108Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563-0.0578693
109Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0427029
110Lysosome_Homo sapiens_hsa04142-0.0411380
111Serotonergic synapse_Homo sapiens_hsa04726-0.0227520

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