GCNT7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sensory perception of chemical stimulus (GO:0007606)6.36439833
2cellular response to ethanol (GO:0071361)5.88602106
3cellular extravasation (GO:0045123)5.65563391
4natural killer cell mediated immunity (GO:0002228)5.25386407
5natural killer cell mediated cytotoxicity (GO:0042267)5.25386407
6positive regulation of gamma-delta T cell activation (GO:0046645)5.23713071
7protein insertion into membrane (GO:0051205)4.89550980
8positive regulation by symbiont of host defense response (GO:0052509)4.74452086
9modulation by symbiont of host defense response (GO:0052031)4.74452086
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.74452086
11modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.74452086
12positive regulation by organism of defense response of other organism involved in symbiotic interact4.74452086
13modulation by symbiont of host immune response (GO:0052553)4.74452086
14protein localization to cilium (GO:0061512)4.60236656
15detection of molecule of bacterial origin (GO:0032490)4.48966271
16V(D)J recombination (GO:0033151)4.48038847
17negative regulation of thymocyte apoptotic process (GO:0070244)4.30202178
18interferon-gamma production (GO:0032609)4.15427751
19positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.99355880
20negative regulation of interleukin-12 production (GO:0032695)3.95217581
21hepatocyte apoptotic process (GO:0097284)3.76976883
22response to host immune response (GO:0052572)3.76914253
23response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.76914253
24myeloid leukocyte mediated immunity (GO:0002444)3.76813512
25regulation of interferon-beta biosynthetic process (GO:0045357)3.75955591
26response to muramyl dipeptide (GO:0032495)3.68880403
27regulation of gamma-delta T cell activation (GO:0046643)3.68047780
28establishment of protein localization to Golgi (GO:0072600)3.66731228
29negative regulation of cell killing (GO:0031342)3.65366925
30negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.65366925
31positive regulation of cellular amide metabolic process (GO:0034250)3.64054947
32regulation of B cell receptor signaling pathway (GO:0050855)3.63612720
33regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.56010996
34protein targeting to Golgi (GO:0000042)3.54870739
35neutrophil mediated immunity (GO:0002446)3.51842879
36histone mRNA catabolic process (GO:0071044)3.42756333
37neutrophil activation involved in immune response (GO:0002283)3.41328285
38I-kappaB phosphorylation (GO:0007252)3.40481724
39regulation of female gonad development (GO:2000194)3.40277489
40leukocyte mediated cytotoxicity (GO:0001909)3.35534399
41monoubiquitinated protein deubiquitination (GO:0035520)3.33500248
42retrograde transport, vesicle recycling within Golgi (GO:0000301)3.32083688
43negative regulation of T-helper cell differentiation (GO:0045623)3.31657878
44negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.31657878
45homocysteine metabolic process (GO:0050667)3.30326840
46adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.30022528
47response to folic acid (GO:0051593)3.29900614
48response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.29082527
49response to host (GO:0075136)3.29082527
50response to host defenses (GO:0052200)3.29082527
51macrophage activation involved in immune response (GO:0002281)3.28088780
52detection of biotic stimulus (GO:0009595)3.28037706
53neural tube formation (GO:0001841)3.24711361
54T cell homeostasis (GO:0043029)3.17697715
55myeloid cell activation involved in immune response (GO:0002275)3.17218077
56positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.15287219
57mast cell activation involved in immune response (GO:0002279)3.14844567
58mast cell degranulation (GO:0043303)3.14844567
59macrophage activation (GO:0042116)3.14747666
60response to hydroperoxide (GO:0033194)3.13970454
61regulation of alpha-beta T cell proliferation (GO:0046640)3.13878269
62mast cell activation (GO:0045576)3.11837123
63positive T cell selection (GO:0043368)3.11512925
64B cell proliferation (GO:0042100)3.10681508
65regulation of NFAT protein import into nucleus (GO:0051532)3.09816335
66detection of external biotic stimulus (GO:0098581)3.09575494
67regulation of necroptotic process (GO:0060544)3.08211013
68negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.06873497
69leukocyte aggregation (GO:0070486)3.06723642
70antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.06472956
71positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.06205261
72histone H3-K9 modification (GO:0061647)3.05139408
73protein K63-linked deubiquitination (GO:0070536)3.02799427
74positive regulation of toll-like receptor signaling pathway (GO:0034123)3.02318942
75regulation of RIG-I signaling pathway (GO:0039535)3.02162541
76modulation by symbiont of host cellular process (GO:0044068)3.00521496
77regulation of thymocyte apoptotic process (GO:0070243)3.00290194
78positive regulation of B cell differentiation (GO:0045579)2.99520547
79negative regulation of B cell proliferation (GO:0030889)2.97418019
80regulation of gamma-delta T cell differentiation (GO:0045586)2.97339920
81positive regulation of interferon-alpha production (GO:0032727)2.95612708
82positive regulation of humoral immune response (GO:0002922)2.94509489
83snRNA transcription (GO:0009301)2.94507435
84production of molecular mediator involved in inflammatory response (GO:0002532)2.94388767
85regulation of germinal center formation (GO:0002634)2.94329112
86regulation of dendritic cell antigen processing and presentation (GO:0002604)2.93954991
87T cell proliferation (GO:0042098)2.93747256
88regulation of B cell differentiation (GO:0045577)2.93255116
89positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.92061993
90regulation of T-helper 2 cell differentiation (GO:0045628)2.91496562
91response to peptidoglycan (GO:0032494)2.89494849
92dosage compensation (GO:0007549)2.86946573
93cell proliferation in forebrain (GO:0021846)2.84384806
94innate immune response in mucosa (GO:0002227)2.84296533
95glycogen catabolic process (GO:0005980)2.82495248
96regulation of interferon-alpha production (GO:0032647)2.82447738
97negative T cell selection (GO:0043383)2.81180692
98regulation of fibroblast apoptotic process (GO:2000269)2.81172388
99germinal center formation (GO:0002467)2.81160931
100NIK/NF-kappaB signaling (GO:0038061)2.80380460
101lymphocyte proliferation (GO:0046651)2.78629731
102serine transport (GO:0032329)2.78258723
103mRNA modification (GO:0016556)2.78251787
104embryonic hemopoiesis (GO:0035162)2.78066307
105negative regulation of T cell apoptotic process (GO:0070233)2.77643128
106positive thymic T cell selection (GO:0045059)2.76943553
107positive regulation of tolerance induction (GO:0002645)2.76819098
108positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.75971321
109negative regulation of granulocyte differentiation (GO:0030853)2.74990523
110activated T cell proliferation (GO:0050798)2.73408565
111DNA dealkylation (GO:0035510)2.73255820
112defense response to protozoan (GO:0042832)2.73035474
113positive regulation of alpha-beta T cell proliferation (GO:0046641)2.72802085
114tolerance induction (GO:0002507)2.72145632
115glucan catabolic process (GO:0009251)2.71836479
116mononuclear cell proliferation (GO:0032943)2.71799429
117leukocyte degranulation (GO:0043299)2.71565810
118mature B cell differentiation (GO:0002335)2.71492050
119negative thymic T cell selection (GO:0045060)2.71407374
120regulation of sarcomere organization (GO:0060297)2.71339540
121protein K11-linked deubiquitination (GO:0035871)2.71208001
122negative regulation of lipid storage (GO:0010888)2.70468062
123negative regulation of T cell mediated immunity (GO:0002710)2.69520026
124modulation by virus of host process (GO:0019054)2.69350766
125embryonic retina morphogenesis in camera-type eye (GO:0060059)2.69314751
126microglial cell activation (GO:0001774)2.68257091
127regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.68210250
128regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.67934868
129adaptive immune response (GO:0002250)2.67813238
130positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.67728770
131regulation of tolerance induction (GO:0002643)2.67134108
132positive regulation of interferon-beta production (GO:0032728)2.65504509
133granulocyte activation (GO:0036230)2.65494070
134histone H3-K36 demethylation (GO:0070544)2.64701869
135regulation of bile acid biosynthetic process (GO:0070857)2.64107274
136phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.63615073
137positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.63558856
138positive regulation of triglyceride biosynthetic process (GO:0010867)2.61395016
139B cell receptor signaling pathway (GO:0050853)2.61363929
140positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.60215579
141regulation of interleukin-12 biosynthetic process (GO:0045075)2.59229858
142positive regulation of granulocyte differentiation (GO:0030854)2.57825157
143dentate gyrus development (GO:0021542)2.57246395
144regulation of chromatin binding (GO:0035561)2.56085277
145T cell selection (GO:0045058)2.54872895
146hepatocyte differentiation (GO:0070365)2.54392052
147cellular response to virus (GO:0098586)2.52313559
148regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.52193036
149B cell homeostasis (GO:0001782)2.51414039
150neutrophil activation (GO:0042119)2.51382072
151regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.51336256
152positive regulation of antigen processing and presentation (GO:0002579)2.50982933
153regulation of granulocyte differentiation (GO:0030852)2.46296060
154negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.44034980
155respiratory burst (GO:0045730)2.42868347
156cellular polysaccharide catabolic process (GO:0044247)2.42836392
157detection of other organism (GO:0098543)2.42834118
158positive regulation of interleukin-17 production (GO:0032740)2.42249172
159sensory perception of smell (GO:0007608)10.6567143

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.32346689
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.68345747
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.34354688
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.09317459
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.45368701
6STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse3.39158375
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.00597140
8E2F7_22180533_ChIP-Seq_HELA_Human3.00209584
9IRF8_27001747_Chip-Seq_BMDM_Mouse2.85019242
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.71538961
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.64003897
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.54957652
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.54360356
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.38857494
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.37025436
16IGF1R_20145208_ChIP-Seq_DFB_Human2.36369002
17RUNX_20019798_ChIP-Seq_JUKART_Human2.28938353
18SCL_19346495_ChIP-Seq_HPC-7_Human2.28142812
19GATA1_22025678_ChIP-Seq_K562_Human2.22593657
20SALL1_21062744_ChIP-ChIP_HESCs_Human2.15585183
21NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.15455560
22VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.14008657
23SMAD_19615063_ChIP-ChIP_OVARY_Human2.10056452
24FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.05544005
25Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.97406076
26MYB_21317192_ChIP-Seq_ERMYB_Mouse1.90791621
27ER_23166858_ChIP-Seq_MCF-7_Human1.86723502
28GATA3_27048872_Chip-Seq_THYMUS_Human1.84655155
29STAT4_19710469_ChIP-ChIP_TH1__Mouse1.83836950
30VDR_24787735_ChIP-Seq_THP-1_Human1.70041893
31BP1_19119308_ChIP-ChIP_Hs578T_Human1.58914749
32POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.58786503
33TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58786503
34SPI1_23127762_ChIP-Seq_K562_Human1.56706054
35SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.56483981
36VDR_21846776_ChIP-Seq_THP-1_Human1.56258667
37VDR_24763502_ChIP-Seq_THP-1_Human1.51538378
38ESR1_20079471_ChIP-ChIP_T-47D_Human1.46459611
39TP63_19390658_ChIP-ChIP_HaCaT_Human1.46121546
40GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.45333355
41MYB_26560356_Chip-Seq_TH2_Human1.45095288
42MYC_22102868_ChIP-Seq_BL_Human1.40960512
43AHR_22903824_ChIP-Seq_MCF-7_Human1.40829818
44SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.39918333
45GATA3_26560356_Chip-Seq_TH2_Human1.36827922
46ZNF217_24962896_ChIP-Seq_MCF-7_Human1.36203128
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.36040929
48PU_27001747_Chip-Seq_BMDM_Mouse1.35336102
49MAF_26560356_Chip-Seq_TH1_Human1.34878826
50NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.34320541
51FLI1_27457419_Chip-Seq_LIVER_Mouse1.33019869
52PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32144611
53SMRT_27268052_Chip-Seq_Bcells_Human1.31255724
54E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.29391071
55CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.24328161
56BRD4_27068464_Chip-Seq_AML-cells_Mouse1.22246847
57GATA1_19941827_ChIP-Seq_MEL_Mouse1.22245580
58FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.20658744
59MYB_26560356_Chip-Seq_TH1_Human1.19462449
60PRDM14_20953172_ChIP-Seq_ESCs_Human1.19126935
61RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.18107559
62GATA2_19941826_ChIP-Seq_K562_Human1.15672939
63EWS_26573619_Chip-Seq_HEK293_Human1.15438261
64PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15085786
65EGR1_23403033_ChIP-Seq_LIVER_Mouse1.14561939
66PKCTHETA_26484144_Chip-Seq_BREAST_Human1.14519598
67FUS_26573619_Chip-Seq_HEK293_Human1.12474666
68TCF7_22412390_ChIP-Seq_EML_Mouse1.11211356
69LXR_22158963_ChIP-Seq_LIVER_Mouse1.10436692
70PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09199573
71NOTCH1_21737748_ChIP-Seq_TLL_Human1.09012475
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.08988538
73RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.07688448
74PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06829591
75CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.05795493
76CBP_20019798_ChIP-Seq_JUKART_Human1.05687592
77IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05687592
78SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.04372588
79NFE2_27457419_Chip-Seq_LIVER_Mouse1.04224404
80TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.03804276
81ARNT_22903824_ChIP-Seq_MCF-7_Human1.03757599
82SUZ12_27294783_Chip-Seq_NPCs_Mouse1.03652478
83FOXM1_23109430_ChIP-Seq_U2OS_Human1.02879334
84KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.02719299
85FLI1_21867929_ChIP-Seq_TH2_Mouse1.01875404
86RUNX1_22412390_ChIP-Seq_EML_Mouse1.00640992
87GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00180186
88RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99974163
89GATA1_19941827_ChIP-Seq_MEL86_Mouse0.98690307
90AR_21572438_ChIP-Seq_LNCaP_Human0.97649807
91NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.97282836
92ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96890840
93DROSHA_22980978_ChIP-Seq_HELA_Human0.96081143
94RXR_22108803_ChIP-Seq_LS180_Human0.96068123
95GATA1_19941826_ChIP-Seq_K562_Human0.96021798
96SALL4_22934838_ChIP-ChIP_CD34+_Human0.95628274
97NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95430241
98CIITA_25753668_ChIP-Seq_RAJI_Human0.95357417
99UTX_26944678_Chip-Seq_JUKART_Human0.95134725
100MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.94337039
101EZH2_27294783_Chip-Seq_NPCs_Mouse0.94337018
102SMAD4_21799915_ChIP-Seq_A2780_Human0.94158213
103TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.94082900
104CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93469790
105CTBP2_25329375_ChIP-Seq_LNCAP_Human0.92668488
106NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.92537331
107FOXA2_19822575_ChIP-Seq_HepG2_Human0.92390107
108AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92201257
109GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92093304
110ZFP57_27257070_Chip-Seq_ESCs_Mouse0.92006265
111FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.91990705
112NANOG_18555785_Chip-Seq_ESCs_Mouse0.91204606
113GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89514784
114TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.89348197
115ZNF274_21170338_ChIP-Seq_K562_Hela0.89108943
116KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.88747317
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88526328
118GATA2_22383799_ChIP-Seq_G1ME_Mouse0.88305249
119CDX2_19796622_ChIP-Seq_MESCs_Mouse0.88019292
120GATA2_21666600_ChIP-Seq_HMVEC_Human0.87810058
121E2F1_18555785_Chip-Seq_ESCs_Mouse0.87431278
122VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.87387232
123SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.87217295
124EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.86819542
125CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.85849102
126PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.85797352
127E2F1_21310950_ChIP-Seq_MCF-7_Human0.84893349
128P300_19829295_ChIP-Seq_ESCs_Human0.84821097
129FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.84615035
130STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.84569936
131SPI1_23547873_ChIP-Seq_NB4_Human0.83828562
132VDR_23849224_ChIP-Seq_CD4+_Human0.83782949
133GBX2_23144817_ChIP-Seq_PC3_Human0.83460027
134TAF15_26573619_Chip-Seq_HEK293_Human0.83052495
135FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.81871836
136SOX9_24532713_ChIP-Seq_HFSC_Mouse0.81324107
137CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79544982
138* GF1_26923725_Chip-Seq_HPCs_Mouse0.79324926
139CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.79294411
140PIAS1_25552417_ChIP-Seq_VCAP_Human0.79017480
141STAT3_23295773_ChIP-Seq_U87_Human0.78325200
142TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.77869483
143LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77726205
144ESR2_21235772_ChIP-Seq_MCF-7_Human0.75944550

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction9.45288555
2MP0000569_abnormal_digit_pigmentation4.70516587
3MP0002132_abnormal_respiratory_system3.13152253
4MP0003806_abnormal_nucleotide_metabolis2.59696067
5MP0002009_preneoplasia2.46061224
6MP0003183_abnormal_peptide_metabolism2.39984948
7MP0001835_abnormal_antigen_presentation2.35971738
8MP0005174_abnormal_tail_pigmentation2.34189107
9MP0009278_abnormal_bone_marrow2.26607683
10MP0005058_abnormal_lysosome_morphology2.19025496
11MP0001800_abnormal_humoral_immune2.12325075
12MP0002452_abnormal_antigen_presenting1.96298165
13MP0002419_abnormal_innate_immunity1.95899267
14MP0005451_abnormal_body_composition1.94046212
15MP0009697_abnormal_copulation1.89721444
16MP0003436_decreased_susceptibility_to1.89708123
17MP0003763_abnormal_thymus_physiology1.81729626
18MP0003787_abnormal_imprinting1.80741255
19MP0005410_abnormal_fertilization1.77890202
20MP0005000_abnormal_immune_tolerance1.75573708
21MP0001853_heart_inflammation1.72078656
22MP0002420_abnormal_adaptive_immunity1.71795754
23MP0001819_abnormal_immune_cell1.71148247
24MP0003300_gastrointestinal_ulcer1.70414181
25MP0002723_abnormal_immune_serum1.68554043
26MP0002139_abnormal_hepatobiliary_system1.67001357
27MP0005671_abnormal_response_to1.66511444
28MP0000015_abnormal_ear_pigmentation1.64291107
29MP0003828_pulmonary_edema1.63533800
30MP0002254_reproductive_system_inflammat1.61763547
31MP0005645_abnormal_hypothalamus_physiol1.61721018
32MP0005025_abnormal_response_to1.60306744
33MP0009764_decreased_sensitivity_to1.59836393
34MP0009785_altered_susceptibility_to1.58331586
35MP0008877_abnormal_DNA_methylation1.57378374
36MP0003303_peritoneal_inflammation1.56817596
37MP0003172_abnormal_lysosome_physiology1.56388288
38MP0005397_hematopoietic_system_phenotyp1.54273623
39MP0001545_abnormal_hematopoietic_system1.54273623
40MP0002876_abnormal_thyroid_physiology1.53378318
41MP0005464_abnormal_platelet_physiology1.53025434
42MP0006082_CNS_inflammation1.51225715
43MP0005360_urolithiasis1.44925263
44MP0002398_abnormal_bone_marrow1.42740556
45MP0000685_abnormal_immune_system1.42073509
46MP0004947_skin_inflammation1.39238771
47MP0002928_abnormal_bile_duct1.36514157
48MP0000716_abnormal_immune_system1.35119041
49MP0009765_abnormal_xenobiotic_induced1.34207397
50MP0005408_hypopigmentation1.33184751
51MP0001790_abnormal_immune_system1.33112925
52MP0005387_immune_system_phenotype1.33112925
53MP0004510_myositis1.32893628
54MP0005164_abnormal_response_to1.32641745
55MP0001879_abnormal_lymphatic_vessel1.31391926
56MP0003221_abnormal_cardiomyocyte_apopto1.23759571
57MP0009333_abnormal_splenocyte_physiolog1.20812878
58MP0002166_altered_tumor_susceptibility1.19759571
59MP0008789_abnormal_olfactory_epithelium1.19148765
60MP0000689_abnormal_spleen_morphology1.15755437
61MP0005365_abnormal_bile_salt1.15096499
62MP0001873_stomach_inflammation1.13190071
63MP0005394_taste/olfaction_phenotype1.12960498
64MP0005499_abnormal_olfactory_system1.12960498
65MP0001845_abnormal_inflammatory_respons1.08981255
66MP0004142_abnormal_muscle_tone1.05600757
67MP0008004_abnormal_stomach_pH1.05568962
68MP0002095_abnormal_skin_pigmentation1.04722027
69MP0000604_amyloidosis1.04060375
70MP0002429_abnormal_blood_cell1.03826930
71MP0002396_abnormal_hematopoietic_system1.03788908
72MP0001533_abnormal_skeleton_physiology1.03761948
73MP0003091_abnormal_cell_migration1.03486600
74MP0010155_abnormal_intestine_physiology1.02073961
75MP0009763_increased_sensitivity_to1.00756239
76MP0008469_abnormal_protein_level1.00611054
77MP0003252_abnormal_bile_duct0.98215135
78MP0002148_abnormal_hypersensitivity_rea0.97873520
79MP0001299_abnormal_eye_distance/0.97814190
80MP0004484_altered_response_of0.97503479
81MP0005310_abnormal_salivary_gland0.96996826
82MP0003866_abnormal_defecation0.95071170
83MP0002722_abnormal_immune_system0.94965444
84MP0000858_altered_metastatic_potential0.93571387
85MP0000371_diluted_coat_color0.92075404
86MP0000609_abnormal_liver_physiology0.91586614
87MP0003724_increased_susceptibility_to0.91353013
88MP0002127_abnormal_cardiovascular_syste0.91241272
89MP0002405_respiratory_system_inflammati0.89924917
90MP0004084_abnormal_cardiac_muscle0.89345705
91MP0000249_abnormal_blood_vessel0.88785606
92MP0005076_abnormal_cell_differentiation0.88588165
93MP0002006_tumorigenesis0.88322653
94MP0003690_abnormal_glial_cell0.87139878
95MP0008995_early_reproductive_senescence0.86746644
96MP0003045_fibrosis0.85270430
97MP0008260_abnormal_autophagy0.84442788
98MP0008058_abnormal_DNA_repair0.84347364
99MP0004264_abnormal_extraembryonic_tissu0.84080002
100MP0002138_abnormal_hepatobiliary_system0.80588266
101MP0000703_abnormal_thymus_morphology0.80260080
102MP0010307_abnormal_tumor_latency0.79844764
103MP0002102_abnormal_ear_morphology0.77337423
104MP0009840_abnormal_foam_cell0.76039834
105MP0002933_joint_inflammation0.75339581
106MP0009384_cardiac_valve_regurgitation0.74050348
107MP0002019_abnormal_tumor_incidence0.73383692
108MP0000427_abnormal_hair_cycle0.73304172
109MP0005257_abnormal_intraocular_pressure0.72667751
110MP0003195_calcinosis0.72341554
111MP0009115_abnormal_fat_cell0.72113169
112MP0004808_abnormal_hematopoietic_stem0.71107771
113MP0008875_abnormal_xenobiotic_pharmacok0.70699645
114MP0003453_abnormal_keratinocyte_physiol0.70451149
115MP0005075_abnormal_melanosome_morpholog0.70228176
116MP0000470_abnormal_stomach_morphology0.69594508
117MP0004381_abnormal_hair_follicle0.69461588
118MP0001986_abnormal_taste_sensitivity0.67867747
119MP0003718_maternal_effect0.67546567
120MP0004742_abnormal_vestibular_system0.66032682
121MP0004883_abnormal_blood_vessel0.65412315
122MP0004134_abnormal_chest_morphology0.65274517
123MP0001851_eye_inflammation0.64749147
124MP0001663_abnormal_digestive_system0.64498458
125MP0000465_gastrointestinal_hemorrhage0.64280783
126MP0005376_homeostasis/metabolism_phenot0.64277174
127MP0005220_abnormal_exocrine_pancreas0.64077558
128MP0003656_abnormal_erythrocyte_physiolo0.63825880
129MP0008057_abnormal_DNA_replication0.62711175
130MP0002693_abnormal_pancreas_physiology0.62365761
131MP0008961_abnormal_basal_metabolism0.61740660
132MP0002277_abnormal_respiratory_mucosa0.61287005
133MP0005377_hearing/vestibular/ear_phenot0.60615409
134MP0003878_abnormal_ear_physiology0.60615409
135MP0002332_abnormal_exercise_endurance0.60272291
136MP0003448_altered_tumor_morphology0.58127093
137MP0002998_abnormal_bone_remodeling0.57290734
138MP0001440_abnormal_grooming_behavior0.55609333

Predicted human phenotypes

RankGene SetZ-score
1B lymphocytopenia (HP:0010976)7.63473113
2Abnormality of B cell number (HP:0010975)7.44473196
3Severe combined immunodeficiency (HP:0004430)6.28739266
4Panhypogammaglobulinemia (HP:0003139)6.17614446
5Hypoproteinemia (HP:0003075)5.44972173
6Combined immunodeficiency (HP:0005387)4.94442393
7Granulocytopenia (HP:0001913)4.57482693
8Recurrent abscess formation (HP:0002722)4.36243511
9Abnormality of eosinophils (HP:0001879)4.19053772
10Stomatitis (HP:0010280)4.11929611
11Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.09172796
12Recurrent bacterial skin infections (HP:0005406)4.05656202
13Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.83815956
14Abnormality of T cells (HP:0002843)3.77648036
15Abnormality of the fingertips (HP:0001211)3.68189932
16Autoimmune hemolytic anemia (HP:0001890)3.55014676
17Abnormal biliary tract physiology (HP:0012439)3.46702594
18Bile duct proliferation (HP:0001408)3.46702594
19Elevated erythrocyte sedimentation rate (HP:0003565)3.43211203
20IgG deficiency (HP:0004315)3.18983374
21Autoimmune thrombocytopenia (HP:0001973)3.16556332
22Stomach cancer (HP:0012126)3.14291909
23Abnormality of macrophages (HP:0004311)3.10171665
24Aplasia/Hypoplasia of the thymus (HP:0010515)3.09459212
25Abnormal delayed hypersensitivity skin test (HP:0002963)3.01810343
26Mediastinal lymphadenopathy (HP:0100721)2.97804113
27Recurrent fungal infections (HP:0002841)2.94816886
28Recurrent gram-negative bacterial infections (HP:0005420)2.90131472
29Vasculitis (HP:0002633)2.84247257
30Recurrent viral infections (HP:0004429)2.84098320
31Short nail (HP:0001799)2.83129344
32Submucous cleft hard palate (HP:0000176)2.77598972
33Papillary thyroid carcinoma (HP:0002895)2.77324385
34Rhinitis (HP:0012384)2.73840636
35Bifid tongue (HP:0010297)2.70269324
36Erythroderma (HP:0001019)2.69030303
37Recurrent skin infections (HP:0001581)2.67889243
38Tinnitus (HP:0000360)2.66420642
39Abnormality of the thymus (HP:0000777)2.64038187
40Periodontitis (HP:0000704)2.63654051
41Eczematoid dermatitis (HP:0000976)2.62698145
42Chronic sinusitis (HP:0011109)2.58579519
43Optic neuritis (HP:0100653)2.57839035
44Retrobulbar optic neuritis (HP:0100654)2.57839035
45Abnormality of macular pigmentation (HP:0008002)2.54475156
46Lip pit (HP:0100267)2.54094194
47Papilledema (HP:0001085)2.49100051
48Hyperlipoproteinemia (HP:0010980)2.47725844
49Leukocytosis (HP:0001974)2.46391878
50Gingivitis (HP:0000230)2.46207122
51Recurrent bronchitis (HP:0002837)2.45174602
52Recurrent otitis media (HP:0000403)2.45063927
53Keratoconjunctivitis sicca (HP:0001097)2.44496417
54Hypoplasia of the thymus (HP:0000778)2.43929121
55Depressed nasal tip (HP:0000437)2.43870428
56Molar tooth sign on MRI (HP:0002419)2.41783836
57Abnormality of midbrain morphology (HP:0002418)2.41783836
58Hematochezia (HP:0002573)2.41672596
59Gastrointestinal stroma tumor (HP:0100723)2.38913507
60Poikilocytosis (HP:0004447)2.36570377
61Heterotopia (HP:0002282)2.35976106
62Abnormal hair whorl (HP:0010721)2.35803136
63Prostate neoplasm (HP:0100787)2.34288432
64Genetic anticipation (HP:0003743)2.33848002
65Thyroiditis (HP:0100646)2.32345343
66Neoplasm of the tracheobronchial system (HP:0100552)2.31585745
67Arterial thrombosis (HP:0004420)2.31501359
68Thick nail (HP:0001805)2.29994048
69Sepsis (HP:0100806)2.29488435
70Xerostomia (HP:0000217)2.24473339
71Chronic bronchitis (HP:0004469)2.24344418
72Myocardial infarction (HP:0001658)2.24199847
73T lymphocytopenia (HP:0005403)2.23915147
74Abnormal respiratory motile cilium physiology (HP:0012261)2.23549624
75Keratoconjunctivitis (HP:0001096)2.22215015
76Urethral obstruction (HP:0000796)2.20850129
77Pulmonary infiltrates (HP:0002113)2.20299046
78Abnormality of T cell number (HP:0011839)2.19272522
79Amyloidosis (HP:0011034)2.14127449
80Acute myeloid leukemia (HP:0004808)2.12210818
81Intestinal fistula (HP:0100819)2.11347342
82Gingival bleeding (HP:0000225)2.09864593
83Cellular immunodeficiency (HP:0005374)2.06254911
84Abnormality of T cell physiology (HP:0011840)2.06214412
85Eosinophilia (HP:0001880)2.06057157
86IgA deficiency (HP:0002720)2.05695098
87Congenital stationary night blindness (HP:0007642)2.05291371
88Abolished electroretinogram (ERG) (HP:0000550)2.04746960
89Myositis (HP:0100614)2.03997800
90Abnormality of the axillary hair (HP:0100134)2.03245749
91Abnormality of secondary sexual hair (HP:0009888)2.03245749
92Episodic fever (HP:0001954)2.01147020
93Retinal dysplasia (HP:0007973)1.99266083
94Postural instability (HP:0002172)1.97914678
95Febrile seizures (HP:0002373)1.96688968
96Tubulointerstitial nephritis (HP:0001970)1.96370066
97Osteomyelitis (HP:0002754)1.96246090
98Hypothermia (HP:0002045)1.96066061
99Adactyly (HP:0009776)1.95333576
100Papilloma (HP:0012740)1.94880843
101Verrucae (HP:0200043)1.94880843
102Thyroid carcinoma (HP:0002890)1.94615085
103Sensory axonal neuropathy (HP:0003390)1.94530298
104Colitis (HP:0002583)1.93848635
105Abnormality of the columella (HP:0009929)1.92642319
106Recurrent sinusitis (HP:0011108)1.92516924
107Orchitis (HP:0100796)1.90709099
108Chronic mucocutaneous candidiasis (HP:0002728)1.88486189
109Recurrent cutaneous fungal infections (HP:0011370)1.88486189
110Oligodactyly (hands) (HP:0001180)1.87422192
111Fatigue (HP:0012378)1.87406728
112Leukopenia (HP:0001882)1.87254307
113Acute lymphatic leukemia (HP:0006721)1.85378077
114Chest pain (HP:0100749)1.84615224
115Meningitis (HP:0001287)1.82104487
116Abnormality of sulfur amino acid metabolism (HP:0004339)1.81680421
117Premature loss of primary teeth (HP:0006323)1.81607780
118Agnosia (HP:0010524)1.81379358
119Anosmia (HP:0000458)1.81186464
120Ectopic kidney (HP:0000086)1.81010601
121Neurodegeneration (HP:0002180)1.80393139
122Vacuolated lymphocytes (HP:0001922)1.79806117
123Urticaria (HP:0001025)1.79720313
124Homocystinuria (HP:0002156)1.76728338
125Abnormality of homocysteine metabolism (HP:0010919)1.76728338
126Cellulitis (HP:0100658)1.76513213
127Prominent nose (HP:0000448)1.75768407
128Lymphoma (HP:0002665)1.75396488
129Agammaglobulinemia (HP:0004432)1.75307596
130Alveolar cell carcinoma (HP:0006519)1.74546966
131Gastrointestinal infarctions (HP:0005244)1.72453516
132Absent rod-and cone-mediated responses on ERG (HP:0007688)1.71761762
133Hypochromic anemia (HP:0001931)1.71712185
134Bronchiectasis (HP:0002110)1.70486442
135Widely spaced teeth (HP:0000687)1.68719678
136Abnormality of the corticospinal tract (HP:0002492)1.68025961
137Epidermoid cyst (HP:0200040)1.67899745
138Hemoptysis (HP:0002105)1.66385516
139Hip dysplasia (HP:0001385)1.65351891
140Progressive cerebellar ataxia (HP:0002073)1.64926630
141Peritonitis (HP:0002586)1.63981804
142Spontaneous hematomas (HP:0007420)1.63593193
143Pseudobulbar signs (HP:0002200)1.62561061
144Chromosomal breakage induced by crosslinking agents (HP:0003221)1.62403193
145Entropion (HP:0000621)1.62222144
146Hemiplegia (HP:0002301)1.61776646
147Increased cerebral lipofuscin (HP:0011813)1.60839331
148Abnormality of the pleura (HP:0002103)1.60631209
149Porencephaly (HP:0002132)1.60489116
150Slow saccadic eye movements (HP:0000514)1.60316694
151Encephalitis (HP:0002383)1.60217088
152Chronic hepatic failure (HP:0100626)1.58623148
153Abnormality of cells of the lymphoid lineage (HP:0012140)1.58060605
154Facial diplegia (HP:0001349)1.57022075
155Subacute progressive viral hepatitis (HP:0006572)1.57013568
156Volvulus (HP:0002580)1.55594636
157Pulmonary embolism (HP:0002204)1.54905342
158Pruritus (HP:0000989)1.52356495
159IgM deficiency (HP:0002850)1.52125784

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK3.45081128
2CAMK1D3.21476896
3FRK3.20990651
4MAP3K143.14168380
5TYK22.75558162
6RIPK42.63319419
7LATS12.50744175
8SIK32.28315548
9MAP4K12.28131997
10STK38L2.27637630
11IKBKE2.21010537
12MAP2K32.05064995
13PHKG11.97840861
14PHKG21.97840861
15JAK11.97355184
16AKT31.88742562
17BLK1.85650695
18YES11.85213731
19EIF2AK31.81566973
20MARK31.81522388
21TGFBR21.79371973
22MAP3K131.77718172
23JAK31.77567705
24IRAK11.74150600
25CAMK1G1.70508885
26BMPR21.63412576
27CDK121.60662473
28CAMKK21.58935316
29SIK21.56302204
30TAOK31.55469136
31TBK11.52976979
32SGK21.50951983
33IRAK31.47470445
34MELK1.44334809
35WNK11.41421857
36BMPR1B1.37450229
37SCYL21.35243030
38MST41.35226437
39ZAP701.34801075
40DAPK21.31432963
41IKBKB1.31315524
42IRAK21.28700247
43SGK31.28529235
44MAPK131.26952355
45HCK1.23783412
46CSF1R1.21713012
47PKN11.20591180
48IRAK41.18023723
49STK241.16861976
50SRPK11.16793309
51ACVR1B1.12993616
52NTRK21.11606320
53KIT1.11410303
54PRKCH1.08617071
55RAF11.04239908
56NEK61.03122343
57STK100.99436200
58PRKAA20.99260031
59ERBB30.96643374
60CHUK0.94613670
61ITK0.94545048
62SGK4940.93985488
63SGK2230.93985488
64PIM10.91165402
65SYK0.89054155
66MKNK20.87633214
67GRK10.87394492
68FGFR30.87080942
69TEC0.84964005
70LCK0.84357521
71MAP3K100.84168961
72FGR0.83718974
73MAPK150.83271212
74PRKCQ0.81113659
75MAP3K30.79866021
76ICK0.78026478
77MARK20.77146265
78MAP3K10.75435270
79KSR10.75247332
80MAP3K50.75171163
81GRK60.74144367
82NLK0.73376627
83DAPK10.71951853
84CDC70.71766711
85STK30.71012534
86TLK10.70956535
87CSK0.70712082
88RPS6KB10.70435966
89ERBB20.70070412
90CAMK40.69439641
91CASK0.69363179
92PIK3CA0.68218197
93RPS6KA20.67473964
94PAK30.67017385
95BRD40.66850916
96MAPK110.66296458
97MAP3K70.66048733
98RPS6KL10.65516756
99RPS6KC10.65516756
100FGFR40.65063199
101STK40.64847741
102RPS6KA60.64498088
103INSRR0.62191842
104PTK2B0.61113290
105SGK10.60725000
106CAMK2B0.59413146
107MATK0.58736194
108ABL10.56782011
109MAP3K110.56565984
110PLK40.55861264
111LYN0.55739297
112NUAK10.53694916
113MAP2K40.52555168
114MUSK0.52240193
115FES0.51649538
116RIPK10.51244047
117STK380.51154032
118STK110.50385446
119BTK0.50003377
120PRPF4B0.48642526
121JAK20.48600834
122CDK40.48551869
123TAOK10.47799419
124ERBB40.47672234
125MAPK100.47577445
126MAPK70.47313378
127KSR20.46864194
128PIK3CG0.45646139
129CAMK2D0.44746102
130PDGFRB0.43781941
131TRPM70.43556567
132DYRK1A0.43016197
133TGFBR10.42510941
134PDK20.42243693
135PLK20.42241605
136TRIB30.42123376
137PRKAA10.41456129
138TTN0.41212156
139BCR0.38735468
140VRK10.38237677
141CAMK2G0.37551750
142MAP3K20.37052119
143CSNK1A1L0.36878079
144MAP3K60.36616331
145CHEK20.36105259

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047407.66954496
2Non-homologous end-joining_Homo sapiens_hsa034502.95712268
3Caffeine metabolism_Homo sapiens_hsa002322.30505678
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.03005419
5NOD-like receptor signaling pathway_Homo sapiens_hsa046211.97951362
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.94854857
7Systemic lupus erythematosus_Homo sapiens_hsa053221.88222907
8Fatty acid biosynthesis_Homo sapiens_hsa000611.86849372
9B cell receptor signaling pathway_Homo sapiens_hsa046621.85625760
10Staphylococcus aureus infection_Homo sapiens_hsa051501.75738202
11Primary immunodeficiency_Homo sapiens_hsa053401.62642834
12Non-small cell lung cancer_Homo sapiens_hsa052231.59480613
13Leishmaniasis_Homo sapiens_hsa051401.57252606
14Intestinal immune network for IgA production_Homo sapiens_hsa046721.56574988
15Osteoclast differentiation_Homo sapiens_hsa043801.51497613
16Steroid biosynthesis_Homo sapiens_hsa001001.50041279
17RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.49209703
18Malaria_Homo sapiens_hsa051441.48759391
19Measles_Homo sapiens_hsa051621.43067046
20Type I diabetes mellitus_Homo sapiens_hsa049401.41424808
21Allograft rejection_Homo sapiens_hsa053301.39501794
22T cell receptor signaling pathway_Homo sapiens_hsa046601.37092357
23Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.36680401
24Histidine metabolism_Homo sapiens_hsa003401.31981587
25Hepatitis C_Homo sapiens_hsa051601.31939076
26Graft-versus-host disease_Homo sapiens_hsa053321.31625353
27Toll-like receptor signaling pathway_Homo sapiens_hsa046201.31019375
28Chemokine signaling pathway_Homo sapiens_hsa040621.27307529
29Tuberculosis_Homo sapiens_hsa051521.26072929
30Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.25827411
31mTOR signaling pathway_Homo sapiens_hsa041501.24531770
32Lysine degradation_Homo sapiens_hsa003101.23603956
33Regulation of autophagy_Homo sapiens_hsa041401.20709270
34Sphingolipid metabolism_Homo sapiens_hsa006001.18028572
35ABC transporters_Homo sapiens_hsa020101.17292361
36Prolactin signaling pathway_Homo sapiens_hsa049171.16954205
37Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.13074870
38Influenza A_Homo sapiens_hsa051641.11895544
39TNF signaling pathway_Homo sapiens_hsa046681.10438414
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.10317205
41Pancreatic cancer_Homo sapiens_hsa052121.02162723
42Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.00617336
43Inositol phosphate metabolism_Homo sapiens_hsa005621.00135658
44Hematopoietic cell lineage_Homo sapiens_hsa046400.99048543
45Renal cell carcinoma_Homo sapiens_hsa052110.98845354
46Primary bile acid biosynthesis_Homo sapiens_hsa001200.97282003
47Rheumatoid arthritis_Homo sapiens_hsa053230.96138016
48Hepatitis B_Homo sapiens_hsa051610.91882439
49beta-Alanine metabolism_Homo sapiens_hsa004100.89695434
50Jak-STAT signaling pathway_Homo sapiens_hsa046300.87515173
51Shigellosis_Homo sapiens_hsa051310.87150017
52Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.86827315
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86192749
54Toxoplasmosis_Homo sapiens_hsa051450.84309978
55Alcoholism_Homo sapiens_hsa050340.83646171
56Prostate cancer_Homo sapiens_hsa052150.83363120
57Endometrial cancer_Homo sapiens_hsa052130.82611587
58Viral carcinogenesis_Homo sapiens_hsa052030.82192155
59Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.82085142
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.80632700
61Antigen processing and presentation_Homo sapiens_hsa046120.80222380
62Leukocyte transendothelial migration_Homo sapiens_hsa046700.79879020
63Fatty acid degradation_Homo sapiens_hsa000710.78290934
64Ovarian steroidogenesis_Homo sapiens_hsa049130.78190839
65Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.77285288
66Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75900540
67Apoptosis_Homo sapiens_hsa042100.74983391
68Neurotrophin signaling pathway_Homo sapiens_hsa047220.74756008
69Insulin resistance_Homo sapiens_hsa049310.74673919
70Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73374508
71Pertussis_Homo sapiens_hsa051330.73253843
72VEGF signaling pathway_Homo sapiens_hsa043700.72656852
73Adipocytokine signaling pathway_Homo sapiens_hsa049200.72053313
74Salmonella infection_Homo sapiens_hsa051320.71898118
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70249985
76Bile secretion_Homo sapiens_hsa049760.70089811
77Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67765997
78Peroxisome_Homo sapiens_hsa041460.67579039
79Herpes simplex infection_Homo sapiens_hsa051680.66136737
80Arginine biosynthesis_Homo sapiens_hsa002200.66056160
81Circadian rhythm_Homo sapiens_hsa047100.64981653
82Legionellosis_Homo sapiens_hsa051340.64408946
83Type II diabetes mellitus_Homo sapiens_hsa049300.64316978
84cAMP signaling pathway_Homo sapiens_hsa040240.63877274
85RNA degradation_Homo sapiens_hsa030180.62796558
86Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62508639
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.61512071
88Fanconi anemia pathway_Homo sapiens_hsa034600.61196981
89Epstein-Barr virus infection_Homo sapiens_hsa051690.60859481
90ErbB signaling pathway_Homo sapiens_hsa040120.58813796
91MAPK signaling pathway_Homo sapiens_hsa040100.58455425
92Phagosome_Homo sapiens_hsa041450.57839527
93Transcriptional misregulation in cancer_Homo sapiens_hsa052020.56984373
94Chronic myeloid leukemia_Homo sapiens_hsa052200.56499230
95Dorso-ventral axis formation_Homo sapiens_hsa043200.56315314
96Complement and coagulation cascades_Homo sapiens_hsa046100.54661523
97Fatty acid metabolism_Homo sapiens_hsa012120.54549477
98Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53842779
99Morphine addiction_Homo sapiens_hsa050320.52787558
100Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52569558
101MicroRNAs in cancer_Homo sapiens_hsa052060.49862303
102HIF-1 signaling pathway_Homo sapiens_hsa040660.49793287
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.48969438
104Platelet activation_Homo sapiens_hsa046110.46991367
105FoxO signaling pathway_Homo sapiens_hsa040680.46726953
106Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46192780
107Vitamin digestion and absorption_Homo sapiens_hsa049770.45421405
108Sulfur relay system_Homo sapiens_hsa041220.44691484
109Vibrio cholerae infection_Homo sapiens_hsa051100.43939561
110Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43723291
111HTLV-I infection_Homo sapiens_hsa051660.43705533
112One carbon pool by folate_Homo sapiens_hsa006700.43468659
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43049794
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.42940052
115African trypanosomiasis_Homo sapiens_hsa051430.42587665
116Autoimmune thyroid disease_Homo sapiens_hsa053200.42290673
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.42273877
118Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.42253816
119Small cell lung cancer_Homo sapiens_hsa052220.41777479
120PPAR signaling pathway_Homo sapiens_hsa033200.41342532
121Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41170484
122Colorectal cancer_Homo sapiens_hsa052100.40988640
123Glioma_Homo sapiens_hsa052140.40681416
124Asthma_Homo sapiens_hsa053100.40356205
125Taste transduction_Homo sapiens_hsa047420.40354395
126p53 signaling pathway_Homo sapiens_hsa041150.40273476
127AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.40056159
128Acute myeloid leukemia_Homo sapiens_hsa052210.39545644
129Thyroid cancer_Homo sapiens_hsa052160.39472179
130Lysosome_Homo sapiens_hsa041420.39418954
131Viral myocarditis_Homo sapiens_hsa054160.36047725
132Notch signaling pathway_Homo sapiens_hsa043300.35622744
133Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34368792

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