GDAP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.80386526
2neuron cell-cell adhesion (GO:0007158)5.52710251
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.05613622
4regulation of short-term neuronal synaptic plasticity (GO:0048172)4.84964181
5vocalization behavior (GO:0071625)4.82079660
6nucleobase catabolic process (GO:0046113)4.76776816
7synaptic vesicle exocytosis (GO:0016079)4.74867331
8protein localization to synapse (GO:0035418)4.63598179
9neuronal action potential propagation (GO:0019227)4.62824981
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.62727890
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.62703510
12presynaptic membrane assembly (GO:0097105)4.60971802
13ionotropic glutamate receptor signaling pathway (GO:0035235)4.35609399
14regulation of synaptic vesicle exocytosis (GO:2000300)4.26440669
15presynaptic membrane organization (GO:0097090)4.25973681
16postsynaptic membrane organization (GO:0001941)4.20800834
17regulation of glutamate receptor signaling pathway (GO:1900449)4.14886678
18glutamate receptor signaling pathway (GO:0007215)4.13653565
19glutamate secretion (GO:0014047)4.07068606
20gamma-aminobutyric acid signaling pathway (GO:0007214)3.96078063
21regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.93411350
22synaptic vesicle maturation (GO:0016188)3.92160048
23neuron recognition (GO:0008038)3.88510601
24retinal cone cell development (GO:0046549)3.83738841
25neuron-neuron synaptic transmission (GO:0007270)3.81462074
26synaptic transmission, glutamatergic (GO:0035249)3.81137605
27regulation of synaptic vesicle transport (GO:1902803)3.77561571
28locomotory exploration behavior (GO:0035641)3.71845957
29transmission of nerve impulse (GO:0019226)3.69261635
30neurotransmitter secretion (GO:0007269)3.65207134
31positive regulation of membrane potential (GO:0045838)3.62272768
32positive regulation of synapse assembly (GO:0051965)3.61146209
33neurotransmitter-gated ion channel clustering (GO:0072578)3.59430261
34dendritic spine morphogenesis (GO:0060997)3.58940278
35regulation of excitatory postsynaptic membrane potential (GO:0060079)3.57101201
36negative regulation of synaptic transmission, GABAergic (GO:0032229)3.55001010
37exploration behavior (GO:0035640)3.50851230
38regulation of long-term neuronal synaptic plasticity (GO:0048169)3.49879077
39regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.48048135
40regulation of vesicle fusion (GO:0031338)3.43608843
41regulation of postsynaptic membrane potential (GO:0060078)3.43332902
42G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.42116455
43establishment of mitochondrion localization (GO:0051654)3.41936787
44regulation of neuronal synaptic plasticity (GO:0048168)3.41839553
45regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.41442073
46righting reflex (GO:0060013)3.39846369
47gamma-aminobutyric acid transport (GO:0015812)3.38045955
48axonal fasciculation (GO:0007413)3.35466824
49behavioral response to nicotine (GO:0035095)3.35125836
50positive regulation of dendritic spine development (GO:0060999)3.35010577
51startle response (GO:0001964)3.34893135
52positive regulation of dendritic spine morphogenesis (GO:0061003)3.33189098
53positive regulation of synaptic transmission, GABAergic (GO:0032230)3.31643267
54neurotransmitter transport (GO:0006836)3.30280831
55layer formation in cerebral cortex (GO:0021819)3.29880347
56positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.27671303
57long-term memory (GO:0007616)3.21497621
58glycosphingolipid biosynthetic process (GO:0006688)3.20306126
59synapse assembly (GO:0007416)3.18899484
60membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.18867041
61regulation of synapse assembly (GO:0051963)3.13311256
62regulation of synaptic transmission, glutamatergic (GO:0051966)3.11703899
63regulation of dendritic spine morphogenesis (GO:0061001)3.07854448
64auditory behavior (GO:0031223)3.07392189
65regulation of neurotransmitter secretion (GO:0046928)3.07176101
66synaptic vesicle endocytosis (GO:0048488)3.06310121
67response to histamine (GO:0034776)3.05696723
68synaptic vesicle docking involved in exocytosis (GO:0016081)3.04029331
69membrane depolarization (GO:0051899)3.02557300
70positive regulation of neurotransmitter secretion (GO:0001956)3.01542859
71regulation of synapse structural plasticity (GO:0051823)3.00621947
72negative regulation of neurotransmitter transport (GO:0051589)2.99797049
73regulation of respiratory system process (GO:0044065)2.99568602
74mechanosensory behavior (GO:0007638)2.96363803
75protein polyglutamylation (GO:0018095)2.95247193
76central nervous system projection neuron axonogenesis (GO:0021952)2.95230094
77long-term synaptic potentiation (GO:0060291)2.93399742
78regulation of neurotransmitter levels (GO:0001505)2.93342107
79positive regulation of neurotransmitter transport (GO:0051590)2.92586925
80dendrite development (GO:0016358)2.92130246
81cell migration in hindbrain (GO:0021535)2.91281976
82behavioral defense response (GO:0002209)2.91040785
83behavioral fear response (GO:0001662)2.91040785
84membrane hyperpolarization (GO:0060081)2.90834752
85adult walking behavior (GO:0007628)2.90219749
86retinal ganglion cell axon guidance (GO:0031290)2.90132617
87learning (GO:0007612)2.90101455
88cerebellar Purkinje cell differentiation (GO:0021702)2.90013255
89regulation of dendritic spine development (GO:0060998)2.89294749
90positive regulation of mitochondrial fission (GO:0090141)2.89243941
91regulation of neurotransmitter transport (GO:0051588)2.87795198
92regulation of synaptic transmission, GABAergic (GO:0032228)2.87724451
93fear response (GO:0042596)2.86974429
94proline transport (GO:0015824)2.86743383
95hippocampus development (GO:0021766)2.86712492
96cerebellar granule cell differentiation (GO:0021707)2.85958156
97negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.84399139
98detection of calcium ion (GO:0005513)2.83675757
99dendrite morphogenesis (GO:0048813)2.83548175
100regulation of synaptic plasticity (GO:0048167)2.83018701
101positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.83009457
102regulation of glutamate secretion (GO:0014048)2.82750852
103membrane depolarization during action potential (GO:0086010)2.80325131
104synaptic transmission (GO:0007268)2.79675626
105DNA double-strand break processing (GO:0000729)2.79672080
106response to auditory stimulus (GO:0010996)2.78506367
107neuromuscular process controlling posture (GO:0050884)2.78385318
108regulation of respiratory gaseous exchange (GO:0043576)2.78369612
109innervation (GO:0060384)2.77495808
110response to pheromone (GO:0019236)2.77460195
111synapse organization (GO:0050808)2.77029076
112short-term memory (GO:0007614)2.76438997
113striatum development (GO:0021756)2.75324277
114neurofilament cytoskeleton organization (GO:0060052)2.72851195
115neuronal ion channel clustering (GO:0045161)2.71476675
116C4-dicarboxylate transport (GO:0015740)2.70160296
117regulation of cilium movement (GO:0003352)2.67822038
118nonmotile primary cilium assembly (GO:0035058)2.65281481
119neuromuscular synaptic transmission (GO:0007274)2.62406940
120protein localization to cilium (GO:0061512)2.59440217
121regulation of feeding behavior (GO:0060259)2.58619319
122central nervous system neuron axonogenesis (GO:0021955)2.56222170
123cochlea development (GO:0090102)2.55090344
124sympathetic nervous system development (GO:0048485)2.51180314
125establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.49150136
126mitochondrion transport along microtubule (GO:0047497)2.49150136
127glycerophospholipid catabolic process (GO:0046475)2.48698608
128olfactory bulb development (GO:0021772)2.48498470
129calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.48286046
130regulation of calcium ion-dependent exocytosis (GO:0017158)2.46950619
131behavioral response to ethanol (GO:0048149)2.46726003
132adult behavior (GO:0030534)2.45265253
133negative regulation of cytosolic calcium ion concentration (GO:0051481)2.44781352
134regulation of microtubule-based movement (GO:0060632)2.43579675
135neuronal action potential (GO:0019228)2.43141142
136cerebral cortex radially oriented cell migration (GO:0021799)2.40539675
137positive regulation of amino acid transport (GO:0051957)2.37695287

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.76242018
2GBX2_23144817_ChIP-Seq_PC3_Human3.98084498
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.07529567
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.94011388
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.78143478
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.61239307
7TAF15_26573619_Chip-Seq_HEK293_Human2.50245273
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.48710793
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.48710793
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.45455091
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.44507402
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.42060855
13* REST_21632747_ChIP-Seq_MESCs_Mouse2.41535451
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.36268940
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.31598724
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25706935
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.25551979
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.22600373
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.13137931
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.12154977
21SALL1_21062744_ChIP-ChIP_HESCs_Human2.10479542
22CTBP2_25329375_ChIP-Seq_LNCAP_Human2.09822186
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.03014043
24BMI1_23680149_ChIP-Seq_NPCS_Mouse2.02781466
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.01315841
26* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.99967849
27GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.96782062
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.95038360
29IGF1R_20145208_ChIP-Seq_DFB_Human1.91200422
30CBX2_27304074_Chip-Seq_ESCs_Mouse1.86991249
31* REST_18959480_ChIP-ChIP_MESCs_Mouse1.86747154
32AR_21572438_ChIP-Seq_LNCaP_Human1.81335346
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81063760
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.79656497
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.78726529
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.75729188
37DROSHA_22980978_ChIP-Seq_HELA_Human1.75701780
38EWS_26573619_Chip-Seq_HEK293_Human1.75295293
39* SMAD4_21799915_ChIP-Seq_A2780_Human1.73083360
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.72934100
41P300_19829295_ChIP-Seq_ESCs_Human1.70959689
42RNF2_27304074_Chip-Seq_NSC_Mouse1.68129627
43RARB_27405468_Chip-Seq_BRAIN_Mouse1.65410637
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.64023993
45ZNF274_21170338_ChIP-Seq_K562_Hela1.58811798
46PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56699894
47IKZF1_21737484_ChIP-ChIP_HCT116_Human1.56309832
48CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.55036560
49FUS_26573619_Chip-Seq_HEK293_Human1.51007291
50RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.48320339
51VDR_22108803_ChIP-Seq_LS180_Human1.46931300
52* PIAS1_25552417_ChIP-Seq_VCAP_Human1.45895039
53TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45621644
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.45399727
55* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.44364347
56E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.42827036
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.41643675
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40388794
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.37684221
60SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36013541
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33870869
62CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33858394
63* AR_25329375_ChIP-Seq_VCAP_Human1.31285570
64STAT3_23295773_ChIP-Seq_U87_Human1.31039289
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30995757
66CBP_20019798_ChIP-Seq_JUKART_Human1.30995757
67RBPJ_22232070_ChIP-Seq_NCS_Mouse1.30318600
68* NANOG_18555785_Chip-Seq_ESCs_Mouse1.25249171
69AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25056690
70POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23486280
71NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23426066
72* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.21370016
73MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21302513
74CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21210662
75BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.20796273
76ER_23166858_ChIP-Seq_MCF-7_Human1.19652017
77UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.19484205
78KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18303380
79FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.18198433
80SOX2_21211035_ChIP-Seq_LN229_Gbm1.17319581
81CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.15749720
82MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15488945
83RUNX2_22187159_ChIP-Seq_PCA_Human1.14562521
84NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.14008809
85TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.13646102
86TAL1_26923725_Chip-Seq_HPCs_Mouse1.13429331
87* TCF4_23295773_ChIP-Seq_U87_Human1.12966794
88RING1B_27294783_Chip-Seq_ESCs_Mouse1.12335007
89* FLI1_27457419_Chip-Seq_LIVER_Mouse1.12173404
90MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11125955
91* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.10303471
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09883360
93P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09545391
94TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09534122
95POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09534122
96TP53_22573176_ChIP-Seq_HFKS_Human1.09438631
97* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09215045
98* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08902534
99TCF4_22108803_ChIP-Seq_LS180_Human1.07533808
100PRDM14_20953172_ChIP-Seq_ESCs_Human1.06592300
101* E2F1_18555785_Chip-Seq_ESCs_Mouse1.04356177
102* KDM2B_26808549_Chip-Seq_REH_Human1.02890640
103JUN_21703547_ChIP-Seq_K562_Human1.02657514
104* CMYC_18555785_Chip-Seq_ESCs_Mouse1.02484522
105FLI1_21867929_ChIP-Seq_TH2_Mouse1.01365553
106IRF1_19129219_ChIP-ChIP_H3396_Human1.00889177
107PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00783399
108* P53_22387025_ChIP-Seq_ESCs_Mouse1.00302401
109TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99874335
110NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99543301
111* SOX9_26525672_Chip-Seq_HEART_Mouse0.98302306
112ARNT_22903824_ChIP-Seq_MCF-7_Human0.98004637
113AR_19668381_ChIP-Seq_PC3_Human0.97808746
114RING1B_27294783_Chip-Seq_NPCs_Mouse0.97542317
115* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.96951361
116ZNF217_24962896_ChIP-Seq_MCF-7_Human0.96598969
117ERG_21242973_ChIP-ChIP_JURKAT_Human0.95363593
118YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94384214
119* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.93246771
120* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.92871937
121* SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92288939
122BCAT_22108803_ChIP-Seq_LS180_Human0.91537494
123* SOX2_18555785_Chip-Seq_ESCs_Mouse0.90557003
124KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.89858856

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.28080238
2MP0004859_abnormal_synaptic_plasticity4.62047663
3MP0004270_analgesia3.68160011
4MP0003635_abnormal_synaptic_transmissio3.55403107
5MP0009745_abnormal_behavioral_response2.99005161
6MP0001968_abnormal_touch/_nociception2.97454353
7MP0009046_muscle_twitch2.83809365
8MP0002064_seizures2.78404650
9MP0002063_abnormal_learning/memory/cond2.77476940
10MP0002734_abnormal_mechanical_nocicepti2.71701690
11MP0005423_abnormal_somatic_nervous2.68251399
12MP0006276_abnormal_autonomic_nervous2.62695659
13MP0002572_abnormal_emotion/affect_behav2.57870949
14MP0001486_abnormal_startle_reflex2.55215307
15MP0002272_abnormal_nervous_system2.51169318
16MP0008877_abnormal_DNA_methylation2.47863681
17MP0002736_abnormal_nociception_after2.36137546
18MP0001188_hyperpigmentation2.27095457
19MP0002735_abnormal_chemical_nociception2.23161365
20MP0002067_abnormal_sensory_capabilities2.07105102
21MP0002733_abnormal_thermal_nociception2.06894726
22MP0001529_abnormal_vocalization2.05874161
23MP0002184_abnormal_innervation2.05617103
24MP0001440_abnormal_grooming_behavior2.04617082
25MP0000778_abnormal_nervous_system2.04409301
26MP0001501_abnormal_sleep_pattern2.02589775
27MP0001970_abnormal_pain_threshold1.99114921
28MP0002822_catalepsy1.89998670
29MP0003121_genomic_imprinting1.88343070
30MP0005646_abnormal_pituitary_gland1.80410188
31MP0001984_abnormal_olfaction1.78483840
32MP0002557_abnormal_social/conspecific_i1.78122526
33MP0004924_abnormal_behavior1.74243685
34MP0005386_behavior/neurological_phenoty1.74243685
35MP0001905_abnormal_dopamine_level1.73784179
36MP0006292_abnormal_olfactory_placode1.63877259
37MP0005645_abnormal_hypothalamus_physiol1.63512748
38MP0004142_abnormal_muscle_tone1.58173199
39MP0003890_abnormal_embryonic-extraembry1.55075283
40MP0008569_lethality_at_weaning1.55058640
41MP0000569_abnormal_digit_pigmentation1.54451312
42MP0000955_abnormal_spinal_cord1.54128987
43MP0002653_abnormal_ependyma_morphology1.45921656
44MP0003879_abnormal_hair_cell1.44924281
45MP0002882_abnormal_neuron_morphology1.44118347
46MP0004742_abnormal_vestibular_system1.43944673
47MP0005409_darkened_coat_color1.40750330
48MP0010386_abnormal_urinary_bladder1.39654683
49MP0004145_abnormal_muscle_electrophysio1.39145708
50MP0002909_abnormal_adrenal_gland1.36862485
51MP0004811_abnormal_neuron_physiology1.34239168
52MP0003787_abnormal_imprinting1.33692895
53MP0002066_abnormal_motor_capabilities/c1.32770081
54MP0002638_abnormal_pupillary_reflex1.30860426
55MP0001502_abnormal_circadian_rhythm1.30039040
56MP0009780_abnormal_chondrocyte_physiolo1.29619587
57MP0000631_abnormal_neuroendocrine_gland1.29266314
58MP0005551_abnormal_eye_electrophysiolog1.28530115
59MP0004885_abnormal_endolymph1.27955519
60MP0003329_amyloid_beta_deposits1.27696766
61MP0009379_abnormal_foot_pigmentation1.27270379
62MP0003122_maternal_imprinting1.18617514
63MP0004133_heterotaxia1.17613472
64MP0002102_abnormal_ear_morphology1.16895543
65MP0006072_abnormal_retinal_apoptosis1.15906306
66MP0001986_abnormal_taste_sensitivity1.09874763
67MP0001963_abnormal_hearing_physiology1.09459227
68MP0002876_abnormal_thyroid_physiology1.09391278
69MP0002752_abnormal_somatic_nervous1.09084703
70MP0002229_neurodegeneration1.07792222
71MP0002152_abnormal_brain_morphology1.06096736
72MP0003136_yellow_coat_color1.04385440
73MP0005394_taste/olfaction_phenotype1.02174459
74MP0005499_abnormal_olfactory_system1.02174459
75MP0004858_abnormal_nervous_system0.99783462
76MP0002234_abnormal_pharynx_morphology0.98643008
77MP0005379_endocrine/exocrine_gland_phen0.92099382
78MP0001485_abnormal_pinna_reflex0.92011030
79MP0000026_abnormal_inner_ear0.91797716
80MP0005187_abnormal_penis_morphology0.90813021
81MP0003137_abnormal_impulse_conducting0.89894303
82MP0003123_paternal_imprinting0.87736926
83MP0002837_dystrophic_cardiac_calcinosis0.87421890
84MP0003633_abnormal_nervous_system0.87231212
85MP0003718_maternal_effect0.86712399
86MP0003195_calcinosis0.86200242
87MP0003119_abnormal_digestive_system0.83995656
88MP0003938_abnormal_ear_development0.83592789
89MP0002090_abnormal_vision0.83433246
90MP0003631_nervous_system_phenotype0.83065632
91MP0002069_abnormal_eating/drinking_beha0.83005126
92MP0001664_abnormal_digestion0.81005319
93MP0002233_abnormal_nose_morphology0.80788398
94MP0000427_abnormal_hair_cycle0.80412049
95MP0004215_abnormal_myocardial_fiber0.79236438
96MP0000647_abnormal_sebaceous_gland0.78688509
97MP0005195_abnormal_posterior_eye0.78137107
98MP0002938_white_spotting0.78002553
99MP0002751_abnormal_autonomic_nervous0.77368758
100MP0003634_abnormal_glial_cell0.75768538
101MP0000049_abnormal_middle_ear0.75453766
102MP0000920_abnormal_myelination0.73738814
103MP0004085_abnormal_heartbeat0.72941264
104MP0008789_abnormal_olfactory_epithelium0.70660748
105MP0003698_abnormal_male_reproductive0.70475994
106MP0003011_delayed_dark_adaptation0.70151588
107MP0005171_absent_coat_pigmentation0.70033128
108MP0003937_abnormal_limbs/digits/tail_de0.69775544
109MP0005535_abnormal_body_temperature0.66761490
110MP0003632_abnormal_nervous_system0.64878027
111MP0002163_abnormal_gland_morphology0.64387684
112MP0008872_abnormal_physiological_respon0.63912849
113MP0005253_abnormal_eye_physiology0.63509481
114MP0000013_abnormal_adipose_tissue0.63250861
115MP0003861_abnormal_nervous_system0.62557764
116MP0000751_myopathy0.60533337
117MP0008874_decreased_physiological_sensi0.60373604
118MP0000015_abnormal_ear_pigmentation0.58926558
119MP0004043_abnormal_pH_regulation0.57807822
120MP0004484_altered_response_of0.57776976
121MP0001943_abnormal_respiration0.55042826
122MP0001299_abnormal_eye_distance/0.52550218
123MP0001177_atelectasis0.51612394
124MP0010770_preweaning_lethality0.49908943

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.25340024
2Myokymia (HP:0002411)5.12053609
3Focal seizures (HP:0007359)4.96071680
4Febrile seizures (HP:0002373)4.65146006
5Atonic seizures (HP:0010819)4.60398302
6Epileptic encephalopathy (HP:0200134)4.52088635
7Visual hallucinations (HP:0002367)4.41177303
8Progressive cerebellar ataxia (HP:0002073)4.11887108
9Absence seizures (HP:0002121)3.87885902
10Dialeptic seizures (HP:0011146)3.66091913
11Broad-based gait (HP:0002136)3.57115921
12Abnormality of the labia minora (HP:0012880)3.47552323
13Limb dystonia (HP:0002451)3.40358808
14Generalized tonic-clonic seizures (HP:0002069)3.39120250
15Hyperventilation (HP:0002883)3.34975297
16Gaze-evoked nystagmus (HP:0000640)3.24474566
17Excessive salivation (HP:0003781)3.09067206
18Drooling (HP:0002307)3.09067206
19Action tremor (HP:0002345)2.93472714
20Absent speech (HP:0001344)2.90689853
21Supranuclear gaze palsy (HP:0000605)2.87413103
22Gait imbalance (HP:0002141)2.76329632
23Truncal ataxia (HP:0002078)2.74722614
24Dysmetria (HP:0001310)2.73095330
25Amblyopia (HP:0000646)2.70048933
26Mutism (HP:0002300)2.68837482
27Pancreatic cysts (HP:0001737)2.65300631
28Abnormal eating behavior (HP:0100738)2.62485428
29Hemiparesis (HP:0001269)2.59335245
30Polyphagia (HP:0002591)2.58418361
31Nephronophthisis (HP:0000090)2.57680891
32Neurofibrillary tangles (HP:0002185)2.57635282
33Anxiety (HP:0000739)2.57293317
34Pancreatic fibrosis (HP:0100732)2.57224643
35Abnormality of the corticospinal tract (HP:0002492)2.54578411
36Ankle clonus (HP:0011448)2.52526364
37Lissencephaly (HP:0001339)2.50527039
38Dysdiadochokinesis (HP:0002075)2.48337473
39Intestinal atresia (HP:0011100)2.44264678
40Abnormality of midbrain morphology (HP:0002418)2.43981671
41Molar tooth sign on MRI (HP:0002419)2.43981671
42Retinal dysplasia (HP:0007973)2.43593794
43Abnormal ciliary motility (HP:0012262)2.42355537
44Scanning speech (HP:0002168)2.42280607
45Medial flaring of the eyebrow (HP:0010747)2.39351171
46Epileptiform EEG discharges (HP:0011182)2.39195393
47Dynein arm defect of respiratory motile cilia (HP:0012255)2.38146116
48Absent/shortened dynein arms (HP:0200106)2.38146116
49Nonprogressive disorder (HP:0003680)2.36646233
50Fetal akinesia sequence (HP:0001989)2.35791987
51Urinary bladder sphincter dysfunction (HP:0002839)2.35636032
52True hermaphroditism (HP:0010459)2.33849256
53Agitation (HP:0000713)2.33223309
54Esotropia (HP:0000565)2.32956342
55Hypothermia (HP:0002045)2.32727450
56Genetic anticipation (HP:0003743)2.31514232
57Cerebral inclusion bodies (HP:0100314)2.28842819
58Congenital primary aphakia (HP:0007707)2.28418793
59EEG with generalized epileptiform discharges (HP:0011198)2.27998176
60Cortical dysplasia (HP:0002539)2.24010455
61Abnormal respiratory motile cilium physiology (HP:0012261)2.23916474
62Degeneration of the lateral corticospinal tracts (HP:0002314)2.23426759
63Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.23426759
64Pachygyria (HP:0001302)2.23315073
65Impaired vibration sensation in the lower limbs (HP:0002166)2.22197246
66Poor eye contact (HP:0000817)2.21725743
67Abnormality of binocular vision (HP:0011514)2.21372129
68Diplopia (HP:0000651)2.21372129
69Depression (HP:0000716)2.21132854
70Optic nerve hypoplasia (HP:0000609)2.20048955
71Spastic gait (HP:0002064)2.19547560
72Pheochromocytoma (HP:0002666)2.17609118
73Abnormality of the renal medulla (HP:0100957)2.17584816
74Abnormality of salivation (HP:0100755)2.16220777
75Papilledema (HP:0001085)2.16012368
76Amyotrophic lateral sclerosis (HP:0007354)2.15894599
77Genital tract atresia (HP:0001827)2.14585405
78Nephrogenic diabetes insipidus (HP:0009806)2.11678796
79Vaginal atresia (HP:0000148)2.09545001
80Hypsarrhythmia (HP:0002521)2.09375111
81Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.09373181
82Protruding tongue (HP:0010808)2.06749756
83Termporal pattern (HP:0011008)2.06334876
84Insidious onset (HP:0003587)2.06334876
85Specific learning disability (HP:0001328)2.04095113
86Oligodactyly (hands) (HP:0001180)2.03983555
87Chronic hepatic failure (HP:0100626)2.03688332
88Blue irides (HP:0000635)2.02973354
89Muscular hypotonia of the trunk (HP:0008936)2.02313583
90Abnormal hair whorl (HP:0010721)2.02009453
91Hepatoblastoma (HP:0002884)2.01069077
92Generalized myoclonic seizures (HP:0002123)2.00504917
93Colon cancer (HP:0003003)1.97417471
94Neuroendocrine neoplasm (HP:0100634)1.97319969
95Spastic tetraplegia (HP:0002510)1.96666305
96Impaired smooth pursuit (HP:0007772)1.96303298
97Impaired social interactions (HP:0000735)1.95276058
98Abnormal social behavior (HP:0012433)1.95276058
99Status epilepticus (HP:0002133)1.94498384
100Pendular nystagmus (HP:0012043)1.91724635
101Methylmalonic acidemia (HP:0002912)1.90887980
102* Inability to walk (HP:0002540)1.89496836
103Akinesia (HP:0002304)1.87594867
104* Progressive inability to walk (HP:0002505)1.87550840
105Abnormal respiratory motile cilium morphology (HP:0005938)1.85436864
106Abnormal respiratory epithelium morphology (HP:0012253)1.85436864
107Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84893337
108Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.84755497
109Volvulus (HP:0002580)1.84396592
110Widely spaced teeth (HP:0000687)1.83733831
111Exotropia (HP:0000577)1.82966419
112Failure to thrive in infancy (HP:0001531)1.82851241
113Abnormality of the renal cortex (HP:0011035)1.82783958
114Type II lissencephaly (HP:0007260)1.82297102
115Stereotypic behavior (HP:0000733)1.81503731
116Postaxial hand polydactyly (HP:0001162)1.80602939
117Hypoplasia of the brainstem (HP:0002365)1.80554484
118Aplasia/Hypoplasia of the brainstem (HP:0007362)1.80554484
119Dyskinesia (HP:0100660)1.80100072
120Poor coordination (HP:0002370)1.79764980
121Thyroid-stimulating hormone excess (HP:0002925)1.79764804
122Abnormality of macular pigmentation (HP:0008002)1.79573175
123Congenital stationary night blindness (HP:0007642)1.77855956
124Hyperglycinemia (HP:0002154)1.77507403
125Abnormality of calcium-phosphate metabolism (HP:0100530)1.76677397
126Urinary urgency (HP:0000012)1.76538064
127Delusions (HP:0000746)1.75950692
128Aplasia/Hypoplasia of the tibia (HP:0005772)1.75070611
129Thickened helices (HP:0000391)1.74558166
130Optic disc pallor (HP:0000543)1.74269340
131Generalized hypopigmentation of hair (HP:0011358)1.73537992
132Narrow forehead (HP:0000341)1.70426811
133Morphological abnormality of the pyramidal tract (HP:0002062)1.69300892
134Aplasia/Hypoplasia of the lens (HP:0008063)1.68467133
135Fair hair (HP:0002286)1.68132506
136Renal cortical cysts (HP:0000803)1.67934659
137Poor suck (HP:0002033)1.67298320
138Lower limb muscle weakness (HP:0007340)1.67274192
139Psychosis (HP:0000709)1.67202171
140Abnormality of the metopic suture (HP:0005556)1.67014303
141Bradykinesia (HP:0002067)1.66987291
142Hypoplasia of the corpus callosum (HP:0002079)1.66910871
143Supernumerary spleens (HP:0009799)1.66381182
144Astrocytoma (HP:0009592)1.65702374
145Abnormality of the astrocytes (HP:0100707)1.65702374
146Hypoglycemic coma (HP:0001325)1.64758620
147Labial hypoplasia (HP:0000066)1.60130730

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.37086807
2NTRK33.81606328
3MARK13.40289134
4EPHA43.08747917
5MAP2K72.87561568
6FRK2.86983074
7MAP3K42.79882906
8MUSK2.68114920
9MAP3K92.60682956
10TNIK2.46425781
11MAP3K122.34668752
12MAP4K22.30693228
13TRIM282.20058417
14MINK12.07018434
15NTRK22.01544721
16MAPK131.95012079
17PNCK1.88918765
18CDK191.79717736
19MAP2K41.68678126
20STK38L1.66845265
21GRK51.56631418
22PAK61.55434151
23OXSR11.45793949
24NTRK11.42357417
25RIPK41.37885517
26UHMK11.36229410
27FES1.34722116
28DAPK21.34622163
29LATS21.31671835
30CDK51.29774559
31PLK21.25828600
32CAMK2A1.24360646
33STK391.22186207
34ERBB31.20740751
35KSR21.18870035
36CAMK2B1.17966197
37CSNK1G21.12899998
38KSR11.12394827
39GRK71.10738552
40PHKG21.09719860
41PHKG11.09719860
42ZAK1.07879852
43SIK21.07626036
44FGR1.04965635
45DYRK21.04066557
46PRKCG1.04008325
47STK381.02357995
48BMPR21.01604469
49CAMKK20.97146920
50NME10.96085236
51ARAF0.93171877
52MKNK20.92000128
53MAPKAPK50.90107473
54STK110.89351710
55SGK2230.87990831
56SGK4940.87990831
57MAP3K60.85867608
58LATS10.83044002
59GRK10.82675953
60WNK10.82245635
61BCR0.82118066
62PRPF4B0.82096626
63PRKD30.81764173
64DYRK1A0.81545150
65CSNK1G30.81497928
66DAPK10.79142387
67EPHA30.78327497
68ACVR1B0.78319102
69PLK30.78232154
70TSSK60.77818859
71MARK20.77723653
72PRKCE0.76654965
73FGFR20.76082524
74DYRK30.75236816
75ADRBK20.74758446
76WNK40.74455354
77CDK140.74211858
78CDK180.73618096
79WNK30.72855113
80CAMK2D0.71295983
81CDK150.70889322
82NEK60.70680277
83TNK20.69674670
84LIMK10.69603129
85CAMKK10.69193193
86PKN10.68841409
87BMPR1B0.68015661
88CAMK10.67830267
89MAP3K20.67438169
90PAK30.67353288
91FER0.64946269
92CDK11A0.63802746
93PRKD20.63441141
94CSNK1G10.61878719
95BRAF0.59498583
96CSNK1D0.58787674
97CCNB10.58218349
98INSRR0.57916289
99SGK20.57652489
100AKT30.57307174
101PRKCZ0.57178648
102SGK10.57046146
103CDK30.56638559
104CAMK2G0.56176672
105TYRO30.55044085
106SRPK10.53797105
107MKNK10.53263827
108ADRBK10.52522729
109NUAK10.50488310
110RAF10.50470643
111CSNK1E0.50239715
112CSNK1A1L0.50018920
113HIPK20.49646807
114RPS6KA40.48931573
115RET0.48829712
116PLK10.47419849
117PINK10.46935466
118CDC70.46660268
119MAP3K50.45795914
120MAP3K130.44219768
121CSNK1A10.43757723
122PRKACA0.43748150
123ERBB40.43280369
124PTK2B0.42480346
125MAPK100.42268529
126ROCK20.40681461
127PRKAA10.39629891
128PRKG10.39206064
129EIF2AK30.39194121
130PLK40.38098865
131CAMK40.37150032
132DYRK1B0.36068975
133VRK10.35494144
134PRKACB0.32122081

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.27479132
2Synaptic vesicle cycle_Homo sapiens_hsa047213.03957755
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.89408914
4GABAergic synapse_Homo sapiens_hsa047272.72943223
5Glutamatergic synapse_Homo sapiens_hsa047242.59274054
6Morphine addiction_Homo sapiens_hsa050322.55834351
7Circadian entrainment_Homo sapiens_hsa047132.48382946
8Olfactory transduction_Homo sapiens_hsa047402.40436228
9Amphetamine addiction_Homo sapiens_hsa050312.37116098
10Long-term potentiation_Homo sapiens_hsa047202.33330163
11Taste transduction_Homo sapiens_hsa047422.22856038
12Serotonergic synapse_Homo sapiens_hsa047262.19563119
13Dopaminergic synapse_Homo sapiens_hsa047282.18712616
14Salivary secretion_Homo sapiens_hsa049702.00832743
15Insulin secretion_Homo sapiens_hsa049111.98971131
16Long-term depression_Homo sapiens_hsa047301.98807846
17Butanoate metabolism_Homo sapiens_hsa006501.95315347
18Cocaine addiction_Homo sapiens_hsa050301.89112292
19Protein export_Homo sapiens_hsa030601.88547932
20Collecting duct acid secretion_Homo sapiens_hsa049661.87086573
21Cholinergic synapse_Homo sapiens_hsa047251.84650919
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.73742505
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69671334
24Renin secretion_Homo sapiens_hsa049241.68190742
25Phototransduction_Homo sapiens_hsa047441.58612908
26Calcium signaling pathway_Homo sapiens_hsa040201.56598663
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.56569904
28Gastric acid secretion_Homo sapiens_hsa049711.52726672
29Oxytocin signaling pathway_Homo sapiens_hsa049211.47913367
30Oxidative phosphorylation_Homo sapiens_hsa001901.44760815
31Axon guidance_Homo sapiens_hsa043601.40639818
32Basal transcription factors_Homo sapiens_hsa030221.38353968
33Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.34718396
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.32743930
35GnRH signaling pathway_Homo sapiens_hsa049121.32408084
36Steroid biosynthesis_Homo sapiens_hsa001001.31933020
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.31620882
38Gap junction_Homo sapiens_hsa045401.29448227
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25239648
40Cardiac muscle contraction_Homo sapiens_hsa042601.21706336
41Alzheimers disease_Homo sapiens_hsa050101.19364196
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.19272291
43cAMP signaling pathway_Homo sapiens_hsa040241.18509318
44Vibrio cholerae infection_Homo sapiens_hsa051101.17607896
45Selenocompound metabolism_Homo sapiens_hsa004501.05783664
46Parkinsons disease_Homo sapiens_hsa050121.04547201
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.03695809
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.01313907
49Melanogenesis_Homo sapiens_hsa049161.00601687
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.97309799
51Estrogen signaling pathway_Homo sapiens_hsa049150.95870801
52Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.95391362
53ErbB signaling pathway_Homo sapiens_hsa040120.95184521
54Propanoate metabolism_Homo sapiens_hsa006400.95046425
55cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91998776
56Type II diabetes mellitus_Homo sapiens_hsa049300.89292863
57Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89261590
58Pancreatic secretion_Homo sapiens_hsa049720.88903005
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88845143
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.87838756
61Fanconi anemia pathway_Homo sapiens_hsa034600.84331176
62Huntingtons disease_Homo sapiens_hsa050160.80263640
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.79853118
64Choline metabolism in cancer_Homo sapiens_hsa052310.78970418
65Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.78018833
66Fatty acid elongation_Homo sapiens_hsa000620.77546175
67Dorso-ventral axis formation_Homo sapiens_hsa043200.77132398
68Circadian rhythm_Homo sapiens_hsa047100.75924458
69Ether lipid metabolism_Homo sapiens_hsa005650.75848290
70Phospholipase D signaling pathway_Homo sapiens_hsa040720.74656181
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.72649108
72RNA degradation_Homo sapiens_hsa030180.72322866
73Oocyte meiosis_Homo sapiens_hsa041140.71641604
74Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68089536
75Ovarian steroidogenesis_Homo sapiens_hsa049130.67966624
76Ras signaling pathway_Homo sapiens_hsa040140.67919262
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67614634
78Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.66318760
79Glioma_Homo sapiens_hsa052140.66213607
80beta-Alanine metabolism_Homo sapiens_hsa004100.65279764
81MAPK signaling pathway_Homo sapiens_hsa040100.64643128
82Non-homologous end-joining_Homo sapiens_hsa034500.63805118
83Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62104978
84Alcoholism_Homo sapiens_hsa050340.61342035
85Wnt signaling pathway_Homo sapiens_hsa043100.60661744
86Thyroid hormone synthesis_Homo sapiens_hsa049180.58922443
87Tryptophan metabolism_Homo sapiens_hsa003800.57745735
88RNA polymerase_Homo sapiens_hsa030200.57480748
89SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56363743
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.56315156
91Type I diabetes mellitus_Homo sapiens_hsa049400.55683388
92Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55445807
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54871672
94Sphingolipid metabolism_Homo sapiens_hsa006000.54800385
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54439079
96Fatty acid metabolism_Homo sapiens_hsa012120.54207473
97Vitamin B6 metabolism_Homo sapiens_hsa007500.53305346
98Inositol phosphate metabolism_Homo sapiens_hsa005620.52939741
99Rheumatoid arthritis_Homo sapiens_hsa053230.52274349
100Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.50700529
101Nitrogen metabolism_Homo sapiens_hsa009100.50325014
102Renal cell carcinoma_Homo sapiens_hsa052110.49882837
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49796089
104Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49363072
105Peroxisome_Homo sapiens_hsa041460.49077443
106Folate biosynthesis_Homo sapiens_hsa007900.49011135
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.46691310
108Hippo signaling pathway_Homo sapiens_hsa043900.46327630
109Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46303991
110Homologous recombination_Homo sapiens_hsa034400.45651413
111Fatty acid biosynthesis_Homo sapiens_hsa000610.45531193
112Dilated cardiomyopathy_Homo sapiens_hsa054140.44398177
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44293581
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44014851
115Linoleic acid metabolism_Homo sapiens_hsa005910.43951945
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.42688422
117Cysteine and methionine metabolism_Homo sapiens_hsa002700.40532522
118Rap1 signaling pathway_Homo sapiens_hsa040150.40089505
119Glycerophospholipid metabolism_Homo sapiens_hsa005640.39565935
120VEGF signaling pathway_Homo sapiens_hsa043700.36767456
121Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.35498084
122Hedgehog signaling pathway_Homo sapiens_hsa043400.35213128
123mRNA surveillance pathway_Homo sapiens_hsa030150.34329701
124Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.34097240
125African trypanosomiasis_Homo sapiens_hsa051430.33890588
126alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.33777140
127Glucagon signaling pathway_Homo sapiens_hsa049220.33497518
128Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32600381
129Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32574847
130Metabolic pathways_Homo sapiens_hsa011000.32355880
131RNA transport_Homo sapiens_hsa030130.32201558
132Regulation of autophagy_Homo sapiens_hsa041400.30267639
133Endocytosis_Homo sapiens_hsa041440.28458940
134Maturity onset diabetes of the young_Homo sapiens_hsa049500.24796853
135Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.24542083
136Prion diseases_Homo sapiens_hsa050200.24015748

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