GDPD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1desmosome organization (GO:0002934)5.69514531
2negative regulation of glycoprotein biosynthetic process (GO:0010561)5.65187164
3diol metabolic process (GO:0034311)5.21867700
4negative regulation of cell killing (GO:0031342)5.19013402
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.19013402
6modulation by symbiont of host defense response (GO:0052031)4.95737708
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.95737708
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.95737708
9positive regulation by organism of defense response of other organism involved in symbiotic interact4.95737708
10modulation by symbiont of host immune response (GO:0052553)4.95737708
11positive regulation by symbiont of host defense response (GO:0052509)4.95737708
12receptor recycling (GO:0001881)4.84953420
13detection of bacterium (GO:0016045)4.80538500
14germinal center formation (GO:0002467)4.66232424
15positive regulation of Cdc42 GTPase activity (GO:0043089)4.51925397
16negative regulation of nitric-oxide synthase activity (GO:0051001)4.35386673
17bundle of His cell to Purkinje myocyte communication (GO:0086069)4.33856530
18neutrophil activation involved in immune response (GO:0002283)4.23790372
19macrophage activation involved in immune response (GO:0002281)4.20374345
20negative regulation of glycoprotein metabolic process (GO:1903019)4.08749134
21detection of external biotic stimulus (GO:0098581)3.99520166
22sarcomere organization (GO:0045214)3.98654513
23sulfate transmembrane transport (GO:1902358)3.98241627
24antigen processing and presentation of endogenous antigen (GO:0019883)3.86468475
25leukocyte migration involved in inflammatory response (GO:0002523)3.80006112
26neutrophil activation (GO:0042119)3.63996025
27negative regulation of lymphocyte mediated immunity (GO:0002707)3.57072610
28response to peptidoglycan (GO:0032494)3.53008078
29positive regulation of B cell differentiation (GO:0045579)3.49149888
30detection of molecule of bacterial origin (GO:0032490)3.48071253
31positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.41662899
32regulation of B cell receptor signaling pathway (GO:0050855)3.37115128
33response to interleukin-15 (GO:0070672)3.36199601
34regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.36114146
35detection of biotic stimulus (GO:0009595)3.33701365
36respiratory burst (GO:0045730)3.33495603
37cardiac myofibril assembly (GO:0055003)3.31240038
38negative regulation of cardiac muscle hypertrophy (GO:0010614)3.31160655
39creatine metabolic process (GO:0006600)3.28477908
40positive thymic T cell selection (GO:0045059)3.26567407
41regulation of mast cell degranulation (GO:0043304)3.25141021
42antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.24870488
43antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.24870488
44regulation of ARF GTPase activity (GO:0032312)3.22740506
45myofibril assembly (GO:0030239)3.21942049
46import into cell (GO:0098657)3.20189706
47granulocyte activation (GO:0036230)3.19354518
48regulation of T-helper 2 cell differentiation (GO:0045628)3.17612582
49positive regulation of monocyte chemotaxis (GO:0090026)3.17199683
50cellular response to epinephrine stimulus (GO:0071872)3.16948162
51B cell receptor signaling pathway (GO:0050853)3.16494451
52plasma membrane repair (GO:0001778)3.16369206
53surfactant homeostasis (GO:0043129)3.15617945
54regulation of interferon-beta biosynthetic process (GO:0045357)3.14455013
55negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.14259358
56sulfate transport (GO:0008272)3.14162900
57regulation of water loss via skin (GO:0033561)3.13876295
58regulation of myeloid leukocyte mediated immunity (GO:0002886)3.08883296
59production of molecular mediator involved in inflammatory response (GO:0002532)3.04287865
60negative regulation of T cell mediated immunity (GO:0002710)3.03731712
61negative regulation of leukocyte mediated immunity (GO:0002704)3.03525512
62cellular extravasation (GO:0045123)3.02064240
63establishment of skin barrier (GO:0061436)3.01797075
64negative regulation of muscle hypertrophy (GO:0014741)3.01456289
65regulation of mast cell activation involved in immune response (GO:0033006)3.01398056
66cellular response to interleukin-15 (GO:0071350)2.99795517
67positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.99764501
68response to host immune response (GO:0052572)2.99148608
69response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.99148608
70interferon-gamma secretion (GO:0072643)2.97923206
71response to type I interferon (GO:0034340)2.95751219
72type I interferon signaling pathway (GO:0060337)2.95487348
73cellular response to type I interferon (GO:0071357)2.95487348
74negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.94380649
75leukocyte aggregation (GO:0070486)2.94288098
76regulation of leukocyte degranulation (GO:0043300)2.93764625
77regulation of Cdc42 GTPase activity (GO:0043088)2.91932190
78protein-chromophore linkage (GO:0018298)2.89944461
79immunoglobulin mediated immune response (GO:0016064)2.88829004
80positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.87518047
81actin-myosin filament sliding (GO:0033275)2.86650307
82muscle filament sliding (GO:0030049)2.86650307
83response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.86065191
84response to host (GO:0075136)2.86065191
85response to host defenses (GO:0052200)2.86065191
86positive regulation of gamma-delta T cell activation (GO:0046645)2.85933032
87hepatocyte apoptotic process (GO:0097284)2.85180541
88DNA methylation involved in gamete generation (GO:0043046)2.84510605
89angiogenesis involved in wound healing (GO:0060055)2.84114337
90antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.83551593
91negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.82957835
92myeloid cell activation involved in immune response (GO:0002275)2.82021877
93hydrogen peroxide biosynthetic process (GO:0050665)2.81563891
94negative regulation of interleukin-12 production (GO:0032695)2.80258070
95negative regulation of monooxygenase activity (GO:0032769)2.80134136
96regulation of sequestering of triglyceride (GO:0010889)2.79381755
97regulation of protein glycosylation (GO:0060049)2.77189543
98macrophage activation (GO:0042116)2.76043323
99regulation of the force of heart contraction (GO:0002026)2.76012750
100regulation of interleukin-5 production (GO:0032674)2.74235099
101antigen processing and presentation via MHC class Ib (GO:0002475)2.74083112
102cardiac muscle contraction (GO:0060048)2.73351630
103porphyrin-containing compound biosynthetic process (GO:0006779)2.70668660
104response to muramyl dipeptide (GO:0032495)2.69699181
105positive regulation of regulated secretory pathway (GO:1903307)2.69626598
106regulation of regulated secretory pathway (GO:1903305)2.69448996
107negative regulation of nitric oxide biosynthetic process (GO:0045019)2.68910133
108ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.67923034
109flavonoid metabolic process (GO:0009812)2.67064900
110regulation of interleukin-12 biosynthetic process (GO:0045075)2.66447355
111positive regulation of histone deacetylation (GO:0031065)2.66356585
112positive regulation of mast cell activation (GO:0033005)2.66208678
113regulation of ARF protein signal transduction (GO:0032012)2.64619972
114embryonic process involved in female pregnancy (GO:0060136)2.63407529
115negative regulation of alpha-beta T cell activation (GO:0046636)2.63102839
116chemical homeostasis within a tissue (GO:0048875)2.62817436
117JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.62538978
118peptidyl-tyrosine autophosphorylation (GO:0038083)2.62469754
119negative regulation of interleukin-6 production (GO:0032715)2.61679170
120cardiac muscle tissue morphogenesis (GO:0055008)2.60811640
121ventricular cardiac muscle cell action potential (GO:0086005)2.60666210
122pantothenate metabolic process (GO:0015939)2.59369963
123regulation of monocyte chemotaxis (GO:0090025)2.59228729
124leukocyte degranulation (GO:0043299)2.58316795
125regulation of gamma-delta T cell differentiation (GO:0045586)2.58061863
126lipopolysaccharide metabolic process (GO:0008653)2.53037146
127defense response to protozoan (GO:0042832)2.52785633
128positive regulation of tumor necrosis factor production (GO:0032760)2.52615622
129negative regulation of bone resorption (GO:0045779)2.52611365
130protoporphyrinogen IX metabolic process (GO:0046501)2.52455631
131peptide catabolic process (GO:0043171)2.52189693
132positive regulation of T cell mediated cytotoxicity (GO:0001916)2.51497529
133positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.50698769
134heart contraction (GO:0060047)2.50048380
135heart process (GO:0003015)2.50048380
136mannose metabolic process (GO:0006013)2.49215594
137G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.49189815
138negative regulation of potassium ion transmembrane transport (GO:1901380)2.48818205
139regulation of T cell mediated cytotoxicity (GO:0001914)2.48607845
140phospholipid scrambling (GO:0017121)2.47723442
141positive regulation of interferon-alpha production (GO:0032727)2.47246723
142negative regulation of stress fiber assembly (GO:0051497)2.45593622
1432-oxoglutarate metabolic process (GO:0006103)2.45577888
144response to epinephrine (GO:0071871)2.45033915
145T-helper 1 type immune response (GO:0042088)2.44555719
146cardiolipin metabolic process (GO:0032048)2.43625115
147purinergic nucleotide receptor signaling pathway (GO:0035590)2.41486186
148regulation of B cell differentiation (GO:0045577)2.40493077
149megakaryocyte development (GO:0035855)2.38630197
150negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.37430974
151tetrapyrrole biosynthetic process (GO:0033014)2.37026295
152actin-mediated cell contraction (GO:0070252)2.36876306
153regulation of relaxation of muscle (GO:1901077)2.36781490
154valine metabolic process (GO:0006573)2.36073977
155dendritic cell migration (GO:0036336)2.35289342
156regulation of actin filament-based movement (GO:1903115)2.35212803
157keratinization (GO:0031424)2.33953655
158sphingosine metabolic process (GO:0006670)2.32100068
159regulation of gamma-delta T cell activation (GO:0046643)2.30848027
160detection of other organism (GO:0098543)2.30792523
161muscle tissue morphogenesis (GO:0060415)2.30614225
162positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.30540455
163actomyosin structure organization (GO:0031032)2.30266653
164fatty acid beta-oxidation (GO:0006635)2.29874077
165positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.29520155
166regulation of interferon-alpha production (GO:0032647)2.28665095
167negative regulation of erythrocyte differentiation (GO:0045647)2.27580880
168thymic T cell selection (GO:0045061)2.27104267
169regulation of T cell tolerance induction (GO:0002664)2.26812361
170vascular endothelial growth factor signaling pathway (GO:0038084)2.26554480
171dendritic cell chemotaxis (GO:0002407)2.26523929
172growth hormone receptor signaling pathway (GO:0060396)2.26117450
173positive regulation of cholesterol efflux (GO:0010875)2.25699950
174sphingoid metabolic process (GO:0046519)2.25340397
175lipopolysaccharide-mediated signaling pathway (GO:0031663)2.24479508
176regulation of cholesterol storage (GO:0010885)2.24254590
177positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.24095655
178lymph vessel development (GO:0001945)2.22851774
179positive regulation of p38MAPK cascade (GO:1900745)2.22782207
180regulation of p38MAPK cascade (GO:1900744)2.21926990
181epithelial cell-cell adhesion (GO:0090136)2.20548196
182glomerular visceral epithelial cell development (GO:0072015)2.19413102
183carnitine shuttle (GO:0006853)2.19019836

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.48295483
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.75404066
3GATA1_22025678_ChIP-Seq_K562_Human4.64874892
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.37877535
5IRF8_22096565_ChIP-ChIP_GC-B_Human2.99247248
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.78841821
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.72823346
8GATA1_19941826_ChIP-Seq_K562_Human2.29188025
9MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.19715356
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.18105176
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.16206687
12VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.13363855
13ZNF263_19887448_ChIP-Seq_K562_Human2.12128836
14SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.06061367
15MYC_22102868_ChIP-Seq_BL_Human2.03770025
16THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.97203839
17GATA2_21666600_ChIP-Seq_HMVEC_Human1.93905258
18ESR1_21235772_ChIP-Seq_MCF-7_Human1.93607178
19* ESR2_21235772_ChIP-Seq_MCF-7_Human1.92158000
20NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.90649670
21IRF8_27001747_Chip-Seq_BMDM_Mouse1.90553775
22GATA1_19941827_ChIP-Seq_MEL_Mouse1.90530883
23SCL_19346495_ChIP-Seq_HPC-7_Human1.89222503
24RARG_19884340_ChIP-ChIP_MEFs_Mouse1.86174832
25STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.85750475
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.84537452
27TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.83099091
28IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.82730346
29ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.79028364
30GATA2_19941826_ChIP-Seq_K562_Human1.78568534
31TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.76250736
32P68_20966046_ChIP-Seq_HELA_Human1.73752093
33MAF_26560356_Chip-Seq_TH1_Human1.72961505
34BCL6_27268052_Chip-Seq_Bcells_Human1.69430742
35MYB_21317192_ChIP-Seq_ERMYB_Mouse1.68388076
36CLOCK_20551151_ChIP-Seq_293T_Human1.67306068
37* SMC4_20622854_ChIP-Seq_HELA_Human1.66393830
38CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.66075021
39PPARA_22158963_ChIP-Seq_LIVER_Mouse1.62162520
40VDR_21846776_ChIP-Seq_THP-1_Human1.61733326
41ELK3_25401928_ChIP-Seq_HUVEC_Human1.61087248
42FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.56636180
43P63_26484246_Chip-Seq_KERATINOCYTES_Human1.56293212
44SA1_27219007_Chip-Seq_ERYTHROID_Human1.54973671
45TBX20_22080862_ChIP-Seq_HEART_Mouse1.54389782
46TBX20_22328084_ChIP-Seq_HEART_Mouse1.54389782
47* E2F1_20622854_ChIP-Seq_HELA_Human1.53347478
48KDM2B_26808549_Chip-Seq_SUP-B15_Human1.53291394
49FOXO3_23340844_ChIP-Seq_DLD1_Human1.52096449
50TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50726869
51GATA1_22383799_ChIP-Seq_G1ME_Mouse1.50041318
52RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.49855838
53SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.49584808
54SPI1_23547873_ChIP-Seq_NB4_Human1.49481043
55BRD4_27068464_Chip-Seq_AML-cells_Mouse1.46908045
56RUNX_20019798_ChIP-Seq_JUKART_Human1.45804931
57RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.44988594
58STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.44622583
59PHF8_20622854_ChIP-Seq_HELA_Human1.42764696
60CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.42246093
61RXR_22158963_ChIP-Seq_LIVER_Mouse1.41373600
62TP63_22573176_ChIP-Seq_HFKS_Human1.40644568
63VDR_24763502_ChIP-Seq_THP-1_Human1.40133047
64RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39908464
65CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.39547159
66TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.39453376
67ELF1_20517297_ChIP-Seq_JURKAT_Human1.38703794
68KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.38107128
69CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.37946351
70GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.37500288
71LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.37101389
72KDM2B_26808549_Chip-Seq_DND41_Human1.34167323
73Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.34030533
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.32858087
75TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31075460
76LXR_22158963_ChIP-Seq_LIVER_Mouse1.31050142
77FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.29961258
78EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27059666
79E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.26277393
80LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.25847013
81PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.25767461
82TET1_21451524_ChIP-Seq_MESCs_Mouse1.25692040
83ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.25226591
84KDM2B_26808549_Chip-Seq_K562_Human1.25019463
85IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.24668145
86PU.1_20513432_ChIP-Seq_Bcells_Mouse1.23770905
87VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.23756710
88TCF7_22412390_ChIP-Seq_EML_Mouse1.23518641
89SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.23113835
90ESR1_20079471_ChIP-ChIP_T-47D_Human1.23091247
91TRIM28_21343339_ChIP-Seq_HEK293_Human1.22974276
92UTX_26944678_Chip-Seq_JUKART_Human1.22731552
93STAT1_20625510_ChIP-Seq_HELA_Human1.20981425
94SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20647049
95EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.20340997
96LXR_22292898_ChIP-Seq_THP-1_Human1.19280865
97SA1_27219007_Chip-Seq_Bcells_Human1.18866920
98RACK7_27058665_Chip-Seq_MCF-7_Human1.18865030
99STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.18771616
100PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.18060066
101CTCF_27219007_Chip-Seq_Bcells_Human1.17426668
102KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.16835190
103MYB_26560356_Chip-Seq_TH2_Human1.16773590
104SOX9_24532713_ChIP-Seq_HFSC_Mouse1.16701214
105SPI1_23127762_ChIP-Seq_K562_Human1.16460657
106CREB1_26743006_Chip-Seq_LNCaP_Human1.15520284
107EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.15450595
108CTCF_26484167_Chip-Seq_Bcells_Mouse1.14548587
109DNAJC2_21179169_ChIP-ChIP_NT2_Human1.14003891
110STAT4_19710469_ChIP-ChIP_TH1__Mouse1.13818825
111PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13323573
112RUNX1_22412390_ChIP-Seq_EML_Mouse1.12969798
113SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12156132
114* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.11367592
115GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11245150
116SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11175089
117OCT4_19829295_ChIP-Seq_ESCs_Human1.11077654
118DROSHA_22980978_ChIP-Seq_HELA_Human1.10658806
119CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.10105525
120NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.09476843
121MAF_26560356_Chip-Seq_TH2_Human1.08722216
122KDM2B_26808549_Chip-Seq_JURKAT_Human1.07669588
123P300_27268052_Chip-Seq_Bcells_Human1.07545389
124KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.06718063
125PPAR_26484153_Chip-Seq_NCI-H1993_Human1.06098782
126STAT6_21828071_ChIP-Seq_BEAS2B_Human1.06035883
127PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.05404191
128ATF3_27146783_Chip-Seq_COLON_Human1.05032403
129EGR1_19032775_ChIP-ChIP_M12_Human1.03862050
130GATA2_22383799_ChIP-Seq_G1ME_Mouse1.03246083
131SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.02785481
132SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.02785481
133CTCF_27219007_Chip-Seq_ERYTHROID_Human1.01691078
134KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.01334802
135GATA3_27048872_Chip-Seq_THYMUS_Human1.00249788
136RUNX1_27514584_Chip-Seq_MCF-7_Human0.99354987
137BCOR_27268052_Chip-Seq_Bcells_Human0.98658240
138VDR_24787735_ChIP-Seq_THP-1_Human0.97824766
139SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97653497
140SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.96932459
141PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.96462518
142CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.96265303
143KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.96055064
144NCOR1_26117541_ChIP-Seq_K562_Human0.95478927

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology3.39906669
2MP0002837_dystrophic_cardiac_calcinosis3.36100805
3MP0002796_impaired_skin_barrier3.28286715
4MP0010234_abnormal_vibrissa_follicle3.11909657
5MP0003136_yellow_coat_color2.95708291
6MP0004084_abnormal_cardiac_muscle2.90427194
7MP0003300_gastrointestinal_ulcer2.58389474
8MP0004036_abnormal_muscle_relaxation2.32503120
9MP0005377_hearing/vestibular/ear_phenot2.29977193
10MP0003878_abnormal_ear_physiology2.29977193
11MP0003656_abnormal_erythrocyte_physiolo2.26585649
12MP0002132_abnormal_respiratory_system2.26541450
13MP0003646_muscle_fatigue2.26113865
14MP0004264_abnormal_extraembryonic_tissu2.23510189
15MP0003866_abnormal_defecation2.21079915
16MP0003191_abnormal_cellular_cholesterol2.17768052
17MP0004510_myositis2.10253704
18MP0004130_abnormal_muscle_cell2.08290032
19MP0004947_skin_inflammation2.05458945
20MP0010155_abnormal_intestine_physiology2.04158809
21MP0005501_abnormal_skin_physiology2.03342881
22MP0001835_abnormal_antigen_presentation2.01489628
23MP0005275_abnormal_skin_tensile1.97360393
24MP0003183_abnormal_peptide_metabolism1.96700133
25MP0000751_myopathy1.94376602
26MP0000343_altered_response_to1.93533897
27MP0003879_abnormal_hair_cell1.93422028
28MP0004215_abnormal_myocardial_fiber1.90950849
29MP0003828_pulmonary_edema1.90788664
30MP0005171_absent_coat_pigmentation1.86296819
31MP0005058_abnormal_lysosome_morphology1.82437496
32MP0002277_abnormal_respiratory_mucosa1.79757534
33MP0004147_increased_porphyrin_level1.68116805
34MP0005451_abnormal_body_composition1.67182456
35MP0005330_cardiomyopathy1.67176109
36MP0004185_abnormal_adipocyte_glucose1.66907839
37MP0003172_abnormal_lysosome_physiology1.66720133
38MP0008260_abnormal_autophagy1.65720380
39MP0002972_abnormal_cardiac_muscle1.65024908
40MP0004484_altered_response_of1.64530622
41MP0002166_altered_tumor_susceptibility1.63090931
42MP0008775_abnormal_heart_ventricle1.55542718
43MP0003303_peritoneal_inflammation1.55226422
44MP0004087_abnormal_muscle_fiber1.54990074
45MP0005085_abnormal_gallbladder_physiolo1.52260558
46MP0003566_abnormal_cell_adhesion1.51436866
47MP0005075_abnormal_melanosome_morpholog1.50862978
48MP0000749_muscle_degeneration1.48670049
49MP0002148_abnormal_hypersensitivity_rea1.48474738
50MP0001790_abnormal_immune_system1.48130299
51MP0005387_immune_system_phenotype1.48130299
52MP0003453_abnormal_keratinocyte_physiol1.46382346
53MP0003436_decreased_susceptibility_to1.46213149
54MP0003724_increased_susceptibility_to1.43417332
55MP0005409_darkened_coat_color1.41679797
56MP0010630_abnormal_cardiac_muscle1.41174847
57MP0000465_gastrointestinal_hemorrhage1.40389951
58MP0002419_abnormal_innate_immunity1.39279670
59MP0005000_abnormal_immune_tolerance1.38363095
60MP0002396_abnormal_hematopoietic_system1.38173915
61MP0001544_abnormal_cardiovascular_syste1.37947324
62MP0005385_cardiovascular_system_phenoty1.37947324
63MP0004043_abnormal_pH_regulation1.36843662
64MP0005025_abnormal_response_to1.35456930
65MP0006082_CNS_inflammation1.34151676
66MP0000716_abnormal_immune_system1.33521834
67MP0008961_abnormal_basal_metabolism1.33294476
68MP0002009_preneoplasia1.32873901
69MP0002006_tumorigenesis1.32349047
70MP0001216_abnormal_epidermal_layer1.32045939
71MP0009840_abnormal_foam_cell1.31330923
72MP0005464_abnormal_platelet_physiology1.31227419
73MP0005670_abnormal_white_adipose1.30617988
74MP0000750_abnormal_muscle_regeneration1.29728019
75MP0003890_abnormal_embryonic-extraembry1.28821770
76MP0004381_abnormal_hair_follicle1.28775707
77MP0005365_abnormal_bile_salt1.28405155
78MP0005666_abnormal_adipose_tissue1.28308312
79MP0001853_heart_inflammation1.25502550
80MP0005620_abnormal_muscle_contractility1.22197151
81MP0001800_abnormal_humoral_immune1.21308258
82MP0000678_abnormal_parathyroid_gland1.20733497
83MP0000685_abnormal_immune_system1.19998924
84MP0005076_abnormal_cell_differentiation1.19655792
85MP0002452_abnormal_antigen_presenting1.17231034
86MP0002098_abnormal_vibrissa_morphology1.17030847
87MP0002722_abnormal_immune_system1.14754153
88MP0003941_abnormal_skin_development1.14521880
89MP0002723_abnormal_immune_serum1.13399853
90MP0009333_abnormal_splenocyte_physiolog1.13057086
91MP0006138_congestive_heart_failure1.12188591
92MP0003950_abnormal_plasma_membrane1.11012229
93MP0002420_abnormal_adaptive_immunity1.10925186
94MP0005360_urolithiasis1.09911720
95MP0002877_abnormal_melanocyte_morpholog1.09637705
96MP0001819_abnormal_immune_cell1.08324676
97MP0005671_abnormal_response_to1.08126470
98MP0000470_abnormal_stomach_morphology1.07627188
99MP0003045_fibrosis1.07406352
100MP0001663_abnormal_digestive_system1.07272060
101MP0005375_adipose_tissue_phenotype1.04796763
102MP0002106_abnormal_muscle_physiology1.04711150
103MP0009785_altered_susceptibility_to1.04213621
104MP0002971_abnormal_brown_adipose1.03640498
105MP0002060_abnormal_skin_morphology1.03550443
106MP0010771_integument_phenotype1.03060616
107MP0009764_decreased_sensitivity_to1.03027563
108MP0010678_abnormal_skin_adnexa1.02825980
109MP0000703_abnormal_thymus_morphology1.02699555
110MP0002429_abnormal_blood_cell1.02038986
111MP0003705_abnormal_hypodermis_morpholog1.00472601
112MP0000490_abnormal_crypts_of1.00400330
113MP0001845_abnormal_inflammatory_respons0.98135356
114MP0005319_abnormal_enzyme/_coenzyme0.97607810
115MP0000689_abnormal_spleen_morphology0.97268774
116MP0000858_altered_metastatic_potential0.96894178
117MP0003448_altered_tumor_morphology0.96676069
118MP0008004_abnormal_stomach_pH0.96320176
119MP0009931_abnormal_skin_appearance0.95157738
120MP0005310_abnormal_salivary_gland0.94009397
121MP0002138_abnormal_hepatobiliary_system0.93657984
122MP0005165_increased_susceptibility_to0.93160374
123MP0001533_abnormal_skeleton_physiology0.92088952
124MP0003763_abnormal_thymus_physiology0.91791233
125MP0005083_abnormal_biliary_tract0.90720687
126MP0002405_respiratory_system_inflammati0.90467293
127MP0009643_abnormal_urine_homeostasis0.90292317
128MP0006036_abnormal_mitochondrial_physio0.88948098
129MP0001879_abnormal_lymphatic_vessel0.88598678
130MP0008469_abnormal_protein_level0.88419508
131MP0000377_abnormal_hair_follicle0.85101221
132MP0006054_spinal_hemorrhage0.84492993
133MP0009278_abnormal_bone_marrow0.83996799
134MP0002398_abnormal_bone_marrow0.81094368
135MP0001873_stomach_inflammation0.80759117
136MP0000747_muscle_weakness0.79868841
137MP0000015_abnormal_ear_pigmentation0.77866487
138MP0002168_other_aberrant_phenotype0.77292988
139MP0010352_gastrointestinal_tract_polyps0.76739665
140MP0002933_joint_inflammation0.76607503
141MP0001851_eye_inflammation0.75015215
142MP0001765_abnormal_ion_homeostasis0.73479926
143MP0009115_abnormal_fat_cell0.72699021
144MP0005381_digestive/alimentary_phenotyp0.71524545
145MP0008874_decreased_physiological_sensi0.68661684
146MP0002095_abnormal_skin_pigmentation0.68480552
147MP0002075_abnormal_coat/hair_pigmentati0.63646657
148MP0000367_abnormal_coat/_hair0.62651154
149MP0002998_abnormal_bone_remodeling0.61724545

Predicted human phenotypes

RankGene SetZ-score
1Ventricular tachycardia (HP:0004756)5.05260200
2Right ventricular cardiomyopathy (HP:0011663)4.92392141
3Amelogenesis imperfecta (HP:0000705)4.83705120
4Sudden death (HP:0001699)4.62041309
5Increased IgE level (HP:0003212)4.44694474
6Hyporeflexia of lower limbs (HP:0002600)4.37910881
7Tetraparesis (HP:0002273)4.36652134
8Myositis (HP:0100614)4.06764531
9Abnormality of macrophages (HP:0004311)4.06641464
10Muscle fiber splitting (HP:0003555)3.90450048
11Orchitis (HP:0100796)3.85802312
12Bilateral sensorineural hearing impairment (HP:0008619)3.80851806
13Eczematoid dermatitis (HP:0000976)3.70200120
14Polycythemia (HP:0001901)3.48464661
15Obstructive lung disease (HP:0006536)3.47579549
16Chronic obstructive pulmonary disease (HP:0006510)3.47579549
17Testicular atrophy (HP:0000029)3.45999380
18Acanthocytosis (HP:0001927)3.45043235
19Gastrointestinal infarctions (HP:0005244)3.41717219
20Elevated erythrocyte sedimentation rate (HP:0003565)3.36928971
21Recurrent fungal infections (HP:0002841)3.36456333
22Calf muscle hypertrophy (HP:0008981)3.35269525
23Recurrent gram-negative bacterial infections (HP:0005420)3.31932532
24Abnormality of the left ventricular outflow tract (HP:0011103)3.29922083
25Subaortic stenosis (HP:0001682)3.29922083
26Retrobulbar optic neuritis (HP:0100654)3.29347677
27Optic neuritis (HP:0100653)3.29347677
28Exercise-induced muscle cramps (HP:0003710)3.28796364
29Gangrene (HP:0100758)3.15435457
30Erythroderma (HP:0001019)3.10447525
31Exercise-induced myalgia (HP:0003738)3.02831008
32Muscle hypertrophy of the lower extremities (HP:0008968)2.98378971
33Petechiae (HP:0000967)2.95127961
34Recurrent skin infections (HP:0001581)2.93068267
35Abnormal delayed hypersensitivity skin test (HP:0002963)2.92939912
36Gastrointestinal inflammation (HP:0004386)2.92507919
37Hypochromic anemia (HP:0001931)2.90860841
38Meningitis (HP:0001287)2.90613405
39Increased connective tissue (HP:0009025)2.90063676
40Lipoatrophy (HP:0100578)2.89654908
41Atrial fibrillation (HP:0005110)2.85613749
42Myoglobinuria (HP:0002913)2.84448430
43Gingivitis (HP:0000230)2.82773879
44Distal lower limb muscle weakness (HP:0009053)2.78525571
45Poikilocytosis (HP:0004447)2.78307447
46Recurrent abscess formation (HP:0002722)2.77845695
47EMG: myopathic abnormalities (HP:0003458)2.77332296
48Sepsis (HP:0100806)2.74557812
49Vasculitis (HP:0002633)2.72625521
50Severe visual impairment (HP:0001141)2.70988558
51Stomatitis (HP:0010280)2.70467180
52Panhypogammaglobulinemia (HP:0003139)2.68698219
53Congenital ichthyosiform erythroderma (HP:0007431)2.66651343
54Keratoconjunctivitis sicca (HP:0001097)2.66241101
55Primary atrial arrhythmia (HP:0001692)2.63686488
56Mediastinal lymphadenopathy (HP:0100721)2.63517890
57Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.59283534
58Hemoptysis (HP:0002105)2.58291263
59Abnormality of fatty-acid metabolism (HP:0004359)2.56583589
60Recurrent bacterial skin infections (HP:0005406)2.55573189
61Interstitial pulmonary disease (HP:0006530)2.55278934
62Axonal loss (HP:0003447)2.54064899
63Supraventricular tachycardia (HP:0004755)2.53611525
64Pustule (HP:0200039)2.52092211
65Supraventricular arrhythmia (HP:0005115)2.51454952
66Myocardial infarction (HP:0001658)2.51109134
67Rectal prolapse (HP:0002035)2.51037278
68Dilated cardiomyopathy (HP:0001644)2.50924547
69Cholelithiasis (HP:0001081)2.48891621
70Asymmetric septal hypertrophy (HP:0001670)2.48262139
71Esophageal varix (HP:0002040)2.47794437
72Hypochromic microcytic anemia (HP:0004840)2.46261935
73Keratoconjunctivitis (HP:0001096)2.45160417
74Chronic mucocutaneous candidiasis (HP:0002728)2.40640309
75Recurrent cutaneous fungal infections (HP:0011370)2.40640309
76Paralysis (HP:0003470)2.38661114
77Parakeratosis (HP:0001036)2.37540309
78Autoimmune thrombocytopenia (HP:0001973)2.36863983
79Abnormality of the calf musculature (HP:0001430)2.36688776
80Palmoplantar keratoderma (HP:0000982)2.35495047
81Conjunctival hamartoma (HP:0100780)2.34735554
82Ventricular fibrillation (HP:0001663)2.33886383
83Hematochezia (HP:0002573)2.33880210
84Abnormality of monocarboxylic acid metabolism (HP:0010996)2.32085060
85Spontaneous hematomas (HP:0007420)2.32006791
86Severe Myopia (HP:0011003)2.31342049
87Difficulty running (HP:0009046)2.30329909
88Cerebral hemorrhage (HP:0001342)2.30137532
89Reticulocytosis (HP:0001923)2.30091960
90Flat acetabular roof (HP:0003180)2.29574299
91Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.28624434
92Encephalitis (HP:0002383)2.28487820
93Rhabdomyolysis (HP:0003201)2.27317747
94Thin bony cortex (HP:0002753)2.24692030
95Peritonitis (HP:0002586)2.21709875
96Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.19786259
97Increased cerebral lipofuscin (HP:0011813)2.19624245
98Pulmonary embolism (HP:0002204)2.18744930
99Abnormal gallbladder morphology (HP:0012437)2.18062876
100Hyperactive renin-angiotensin system (HP:0000841)2.16903197
101Hemorrhage of the eye (HP:0011885)2.16841577
102Erythema (HP:0010783)2.15360190
103Urticaria (HP:0001025)2.15302319
104Mesangial abnormality (HP:0001966)2.14987119
105Syncope (HP:0001279)2.12189150
106Hypotrichosis (HP:0001006)2.10434852
107Increased neuronal autofluorescent lipopigment (HP:0002074)2.07565633
108Systemic lupus erythematosus (HP:0002725)2.07416830
109Ventricular arrhythmia (HP:0004308)2.07018634
110Areflexia of lower limbs (HP:0002522)2.06919438
111Facial diplegia (HP:0001349)2.06553246
112Segmental peripheral demyelination/remyelination (HP:0003481)2.06362459
113Malnutrition (HP:0004395)2.06231080
114Colitis (HP:0002583)2.05815667
115Cellulitis (HP:0100658)2.05128765
116Granulocytopenia (HP:0001913)2.04308026
117Epistaxis (HP:0000421)2.02938244
118Palpitations (HP:0001962)1.99719256
119J-shaped sella turcica (HP:0002680)1.99392526
120Hyperbilirubinemia (HP:0002904)1.97613888
121Vacuolated lymphocytes (HP:0001922)1.97583281
122Abnormality of the nasal mucosa (HP:0000433)1.97059191
123Esophageal neoplasm (HP:0100751)1.95768021
124Neoplasm of head and neck (HP:0012288)1.95768021
125Abnormality of the fingertips (HP:0001211)1.95291791
126Hypergammaglobulinemia (HP:0010702)1.95282225
127Chest pain (HP:0100749)1.94634690
128Palmoplantar hyperkeratosis (HP:0000972)1.94595595
129Anorexia (HP:0002039)1.94348011
130Gingival bleeding (HP:0000225)1.94222830
131Premature loss of primary teeth (HP:0006323)1.93047909
132Woolly hair (HP:0002224)1.92241474
133Nephritis (HP:0000123)1.92206721
134Recurrent viral infections (HP:0004429)1.92083603
135Episodic fever (HP:0001954)1.91268011
136Metaphyseal cupping (HP:0003021)1.91194161
137Myotonia (HP:0002486)1.90657400
138Sudden cardiac death (HP:0001645)1.90514044
139Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.89838938
140Chronic diarrhea (HP:0002028)1.89360624
141Impaired platelet aggregation (HP:0003540)1.88522817
142Abnormal platelet function (HP:0011869)1.88522817
143Decreased circulating renin level (HP:0003351)1.88261109
144Seborrheic dermatitis (HP:0001051)1.88042290
145Cheilitis (HP:0100825)1.87258628
146Dehydration (HP:0001944)1.84844276
147T lymphocytopenia (HP:0005403)1.84675995
148Bundle branch block (HP:0011710)1.84145866
149Verrucae (HP:0200043)1.81661770
150Papilloma (HP:0012740)1.81661770
151Lymphopenia (HP:0001888)1.81117328
152Pili torti (HP:0003777)1.80206217
153Emphysema (HP:0002097)1.79772921
154Inflammation of the large intestine (HP:0002037)1.79039481
155Increased serum ferritin (HP:0003281)1.78819799
156Abnormality of nail color (HP:0100643)1.78526556
157Distal lower limb amyotrophy (HP:0008944)1.78193743
158Leukocytosis (HP:0001974)1.78104243
159Microcytic anemia (HP:0001935)1.77998464
160Purpura (HP:0000979)1.77542770
161Prolonged bleeding time (HP:0003010)1.77322094
162Skin ulcer (HP:0200042)1.76267798
163Vertebral arch anomaly (HP:0008438)1.75430971
164Thickened calvaria (HP:0002684)1.75406582
165Deformed sella turcica (HP:0002681)1.73676418
166Abnormality of T cells (HP:0002843)1.72336100
167Glomerulonephritis (HP:0000099)1.72228181
168Nasal polyposis (HP:0100582)1.70844279
169Acne (HP:0001061)1.70369022
170Gastrointestinal stroma tumor (HP:0100723)1.70194910
171Widely patent fontanelles and sutures (HP:0004492)1.70030400
172Prolonged QT interval (HP:0001657)1.69507940
173Abnormality of T cell number (HP:0011839)1.69501318

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS15.16641531
2MST43.11870094
3TTN3.05628503
4EPHB12.77739436
5STK38L2.72479228
6LATS22.54519648
7LMTK22.52755821
8MAP4K12.36668170
9STK382.31852733
10KSR22.30850966
11DMPK2.11520238
12BLK2.11080513
13TYK22.03957875
14TRIB31.99821700
15ZAP701.94642750
16ERN11.82604477
17LRRK21.79312423
18FGFR41.78405009
19CDK121.77831098
20TAOK31.77324558
21PRKD31.72770856
22TBK11.70846367
23TGFBR21.67743341
24JAK11.67559436
25MYLK1.66006051
26MAPKAPK31.62677007
27PRPF4B1.58359759
28SYK1.56709855
29BCKDK1.53848292
30STK101.48030412
31IRAK31.47370000
32RIPK41.46323110
33PHKG21.46241462
34PHKG11.46241462
35EPHA31.45460038
36STK41.41657610
37MAP3K141.37962262
38TIE11.36916928
39RIPK11.35386481
40NLK1.32979529
41MAP3K111.32052456
42JAK21.30907847
43SMG11.27903677
44EPHA21.24476704
45MARK21.23679119
46MAP3K31.22059450
47JAK31.21066307
48PTK61.20815134
49EEF2K1.18709714
50SIK31.18400722
51FES1.16995960
52PRKD11.15785698
53MAP3K71.15299387
54ITK1.14829660
55PIM21.14519703
56TRPM71.14076164
57MATK1.12013910
58MAP3K61.11253329
59DYRK1B1.10984158
60BTK1.08666544
61MAP3K21.07406398
62IKBKE1.06773740
63ACVR1B1.06682318
64HCK1.05559370
65FGFR31.02797110
66MELK1.02482775
67PKN21.00755249
68IKBKB1.00181187
69MAP3K130.99960220
70MAP2K30.99114213
71PRKD20.98883021
72MST1R0.93320284
73TNK20.91977997
74PIK3CA0.90204625
75PIM10.87345020
76RPS6KL10.86778996
77RPS6KC10.86778996
78IRAK20.86024077
79NME10.85437399
80FER0.83881445
81SIK10.83581060
82RPS6KA60.83212754
83MAP3K10.81811477
84OBSCN0.80886000
85PTK2B0.80089302
86PKN10.80035445
87CDC42BPA0.79719506
88PRKAA20.79145053
89CDK60.76626508
90GRK60.76435723
91KIT0.74989215
92CSK0.74690206
93FGR0.73318767
94NEK90.71601795
95CHUK0.70895846
96ROCK10.69585284
97LCK0.69301428
98PDK30.68327510
99PDK40.68327510
100PDPK10.67531997
101BMX0.67297735
102TXK0.67013717
103MARK30.65361561
104GRK70.64889466
105YES10.63958425
106KDR0.63231279
107WNK40.62458279
108CLK10.61924285
109RPS6KA20.61702731
110PRKG20.61481960
111CAMK1D0.59996823
112IRAK40.59935423
113PDGFRB0.59909191
114SGK30.59665874
115MAPK120.58787842
116IRAK10.57691114
117CSF1R0.56096997
118ROCK20.56087634
119PDK10.55463629
120CAMK1G0.54810395
121MAP2K60.53534000
122SIK20.52559957
123WNK10.52483529
124MAP2K20.52395856
125STK110.51833997
126PRKCQ0.51355624
127MAP3K100.50795806
128TEC0.49717860
129RET0.49417479
130TAOK10.48824324
131RPS6KB20.48487697
132TESK20.48373459
133PTK20.47627993
134MAP2K10.45183750
135LYN0.44989848
136ICK0.44410096
137STK240.44225343
138MAP2K40.42875290
139PRKCZ0.38917628
140TESK10.37250091
141FYN0.32361483
142MAPK70.31879178
143PIK3CG0.31800980
144MAPKAPK20.31270851

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.68403326
2Leishmaniasis_Homo sapiens_hsa051402.12290478
3Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.10863681
4Propanoate metabolism_Homo sapiens_hsa006402.03542059
5Osteoclast differentiation_Homo sapiens_hsa043801.90044874
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.85915139
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.82410413
8Fatty acid degradation_Homo sapiens_hsa000711.79737343
9Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.70884389
10Cardiac muscle contraction_Homo sapiens_hsa042601.65018076
11Staphylococcus aureus infection_Homo sapiens_hsa051501.63148970
12Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.61698275
13B cell receptor signaling pathway_Homo sapiens_hsa046621.60293736
14Fatty acid elongation_Homo sapiens_hsa000621.57493512
15Dilated cardiomyopathy_Homo sapiens_hsa054141.57076970
16Cyanoamino acid metabolism_Homo sapiens_hsa004601.55148239
17ABC transporters_Homo sapiens_hsa020101.48616065
18Leukocyte transendothelial migration_Homo sapiens_hsa046701.40972035
19Fatty acid metabolism_Homo sapiens_hsa012121.39150989
20Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.38801655
21Toxoplasmosis_Homo sapiens_hsa051451.36487307
22Non-small cell lung cancer_Homo sapiens_hsa052231.35891565
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34965738
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.34862844
25Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.34697567
26Hematopoietic cell lineage_Homo sapiens_hsa046401.34607445
27Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.32217963
28Viral myocarditis_Homo sapiens_hsa054161.30754989
29Adipocytokine signaling pathway_Homo sapiens_hsa049201.30374166
30Lysosome_Homo sapiens_hsa041421.30239092
31Tuberculosis_Homo sapiens_hsa051521.29591842
32Notch signaling pathway_Homo sapiens_hsa043301.28467639
33PPAR signaling pathway_Homo sapiens_hsa033201.25776533
34Primary immunodeficiency_Homo sapiens_hsa053401.22754238
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.22351296
36NF-kappa B signaling pathway_Homo sapiens_hsa040641.21056949
37Graft-versus-host disease_Homo sapiens_hsa053321.18627350
38Insulin resistance_Homo sapiens_hsa049311.17921314
39Other glycan degradation_Homo sapiens_hsa005111.14983134
40Carbon metabolism_Homo sapiens_hsa012001.11676876
41Sphingolipid signaling pathway_Homo sapiens_hsa040711.11043377
42Pertussis_Homo sapiens_hsa051331.11006442
43Choline metabolism in cancer_Homo sapiens_hsa052311.08973170
44Autoimmune thyroid disease_Homo sapiens_hsa053201.08901286
45Caffeine metabolism_Homo sapiens_hsa002321.07980007
46Allograft rejection_Homo sapiens_hsa053301.07071595
47Toll-like receptor signaling pathway_Homo sapiens_hsa046201.06440934
48Endometrial cancer_Homo sapiens_hsa052131.06194464
49Starch and sucrose metabolism_Homo sapiens_hsa005001.03740987
50Phospholipase D signaling pathway_Homo sapiens_hsa040721.03603984
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.02079581
52Salmonella infection_Homo sapiens_hsa051321.01758699
53Platelet activation_Homo sapiens_hsa046111.01307488
54Measles_Homo sapiens_hsa051620.97303427
55GnRH signaling pathway_Homo sapiens_hsa049120.97150032
56Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93551292
57Apoptosis_Homo sapiens_hsa042100.93314081
58alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.91996728
59Amoebiasis_Homo sapiens_hsa051460.91251599
60Intestinal immune network for IgA production_Homo sapiens_hsa046720.89068242
61Jak-STAT signaling pathway_Homo sapiens_hsa046300.88507021
62Phagosome_Homo sapiens_hsa041450.87434533
63Chemokine signaling pathway_Homo sapiens_hsa040620.85498264
64Rheumatoid arthritis_Homo sapiens_hsa053230.85193732
65Glycosaminoglycan degradation_Homo sapiens_hsa005310.84538897
66Parkinsons disease_Homo sapiens_hsa050120.84059093
67Malaria_Homo sapiens_hsa051440.83524265
68VEGF signaling pathway_Homo sapiens_hsa043700.81728887
69NOD-like receptor signaling pathway_Homo sapiens_hsa046210.81569988
70Legionellosis_Homo sapiens_hsa051340.81272982
71Phenylalanine metabolism_Homo sapiens_hsa003600.81020092
72Thyroid cancer_Homo sapiens_hsa052160.80956042
73T cell receptor signaling pathway_Homo sapiens_hsa046600.80272074
74Prolactin signaling pathway_Homo sapiens_hsa049170.78844955
75TNF signaling pathway_Homo sapiens_hsa046680.78735456
76Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.78476636
77Endocytosis_Homo sapiens_hsa041440.78161790
78Oxidative phosphorylation_Homo sapiens_hsa001900.77901803
79African trypanosomiasis_Homo sapiens_hsa051430.77462060
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.77328376
81Acute myeloid leukemia_Homo sapiens_hsa052210.77089482
82Vitamin digestion and absorption_Homo sapiens_hsa049770.76655030
83Pyruvate metabolism_Homo sapiens_hsa006200.73992146
84Collecting duct acid secretion_Homo sapiens_hsa049660.73808765
85Galactose metabolism_Homo sapiens_hsa000520.73360393
86Hepatitis B_Homo sapiens_hsa051610.73163926
87Insulin signaling pathway_Homo sapiens_hsa049100.72704927
88Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.72132895
89Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71599818
90Herpes simplex infection_Homo sapiens_hsa051680.70351164
91ErbB signaling pathway_Homo sapiens_hsa040120.69739554
92HIF-1 signaling pathway_Homo sapiens_hsa040660.68745925
93Sphingolipid metabolism_Homo sapiens_hsa006000.68519318
94Dorso-ventral axis formation_Homo sapiens_hsa043200.68394649
95Colorectal cancer_Homo sapiens_hsa052100.68086233
96Linoleic acid metabolism_Homo sapiens_hsa005910.65875768
97Inositol phosphate metabolism_Homo sapiens_hsa005620.65004815
98FoxO signaling pathway_Homo sapiens_hsa040680.64221352
99Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.64190200
100Complement and coagulation cascades_Homo sapiens_hsa046100.63848447
101Glycerolipid metabolism_Homo sapiens_hsa005610.63540390
102Hepatitis C_Homo sapiens_hsa051600.63293713
103Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.62681122
104Adherens junction_Homo sapiens_hsa045200.62036793
105Pancreatic cancer_Homo sapiens_hsa052120.60786076
106Mineral absorption_Homo sapiens_hsa049780.60248093
107Arginine biosynthesis_Homo sapiens_hsa002200.59335947
108Fructose and mannose metabolism_Homo sapiens_hsa000510.58947411
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58900361
110Alzheimers disease_Homo sapiens_hsa050100.58469375
111Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.57588182
112Antigen processing and presentation_Homo sapiens_hsa046120.57445847
113Tryptophan metabolism_Homo sapiens_hsa003800.57072157
114Arachidonic acid metabolism_Homo sapiens_hsa005900.56941254
115Estrogen signaling pathway_Homo sapiens_hsa049150.56896803
116Peroxisome_Homo sapiens_hsa041460.56181796
117Pancreatic secretion_Homo sapiens_hsa049720.56092964
118Proteoglycans in cancer_Homo sapiens_hsa052050.55102400
119Ovarian steroidogenesis_Homo sapiens_hsa049130.54242872
120Influenza A_Homo sapiens_hsa051640.53264374
121Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.53054246
122Chronic myeloid leukemia_Homo sapiens_hsa052200.52438851
123Lysine degradation_Homo sapiens_hsa003100.51739267
124Bladder cancer_Homo sapiens_hsa052190.51286481
125Fat digestion and absorption_Homo sapiens_hsa049750.51218275
126Carbohydrate digestion and absorption_Homo sapiens_hsa049730.51133306
127Type I diabetes mellitus_Homo sapiens_hsa049400.49542643
128Bile secretion_Homo sapiens_hsa049760.48568052
129Histidine metabolism_Homo sapiens_hsa003400.48119076
130Shigellosis_Homo sapiens_hsa051310.47901870
131Focal adhesion_Homo sapiens_hsa045100.47897800
132N-Glycan biosynthesis_Homo sapiens_hsa005100.47826013
133mTOR signaling pathway_Homo sapiens_hsa041500.47600158
134Neurotrophin signaling pathway_Homo sapiens_hsa047220.46623962
135Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.45360312
136RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.44780634
137Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43617738
138Renal cell carcinoma_Homo sapiens_hsa052110.43365186
139Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42154042
140Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.42144380
141Glycerophospholipid metabolism_Homo sapiens_hsa005640.41690773

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