GEMIN5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of DNA methylation (GO:0044030)6.07709920
2regulation of acrosome reaction (GO:0060046)5.59347008
3regulation of female gonad development (GO:2000194)5.41388342
4nuclear pore organization (GO:0006999)5.31085568
5nuclear pore complex assembly (GO:0051292)5.11520849
6positive regulation of histone H3-K4 methylation (GO:0051571)4.94083251
7protein localization to kinetochore (GO:0034501)4.83082681
8meiotic cell cycle (GO:0051321)4.66324893
9nucleobase biosynthetic process (GO:0046112)4.65474822
10DNA unwinding involved in DNA replication (GO:0006268)4.63469091
11mitotic nuclear envelope disassembly (GO:0007077)4.52805439
12folic acid-containing compound biosynthetic process (GO:0009396)4.43278045
13ribosome assembly (GO:0042255)4.41764343
14oocyte development (GO:0048599)4.40516964
15DNA replication-dependent nucleosome assembly (GO:0006335)4.37279113
16DNA replication-dependent nucleosome organization (GO:0034723)4.37279113
17DNA replication initiation (GO:0006270)4.32224870
18mitotic metaphase plate congression (GO:0007080)4.31433699
19purine nucleobase biosynthetic process (GO:0009113)4.27878383
20IMP biosynthetic process (GO:0006188)4.24578547
21nuclear envelope disassembly (GO:0051081)4.24047347
22membrane disassembly (GO:0030397)4.24047347
23protein localization to chromosome, centromeric region (GO:0071459)4.21200627
24regulation of meiosis I (GO:0060631)4.17686423
25maturation of SSU-rRNA (GO:0030490)4.13933467
26piRNA metabolic process (GO:0034587)4.01251358
27formation of translation preinitiation complex (GO:0001731)3.99814113
28pore complex assembly (GO:0046931)3.99694553
29DNA strand elongation involved in DNA replication (GO:0006271)3.98993081
30binding of sperm to zona pellucida (GO:0007339)3.98776396
31DNA replication checkpoint (GO:0000076)3.98034641
32regulation of spindle organization (GO:0090224)3.90162498
33ribosome biogenesis (GO:0042254)3.89700727
34multicellular organism reproduction (GO:0032504)3.84181517
35DNA strand elongation (GO:0022616)3.79116952
36pre-miRNA processing (GO:0031054)3.74182078
37regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.73294413
38metaphase plate congression (GO:0051310)3.70907636
39mitotic sister chromatid segregation (GO:0000070)3.67099300
40IMP metabolic process (GO:0046040)3.64084267
41negative regulation of reproductive process (GO:2000242)3.61778783
42female gamete generation (GO:0007292)3.61608439
43positive regulation of chromosome segregation (GO:0051984)3.59375796
44regulation of posttranscriptional gene silencing (GO:0060147)3.58762723
45regulation of gene silencing by miRNA (GO:0060964)3.58762723
46regulation of gene silencing by RNA (GO:0060966)3.58762723
47DNA methylation involved in gamete generation (GO:0043046)3.58154214
48DNA duplex unwinding (GO:0032508)3.58036902
49DNA geometric change (GO:0032392)3.56887890
50positive regulation of histone methylation (GO:0031062)3.55752050
51regulation of translational termination (GO:0006449)3.55639680
52regulation of histone H3-K9 methylation (GO:0051570)3.53890082
53gene silencing by RNA (GO:0031047)3.49092525
54mitotic chromosome condensation (GO:0007076)3.47832548
55heterochromatin organization (GO:0070828)3.46714829
56sister chromatid segregation (GO:0000819)3.46025788
57regulation of spindle checkpoint (GO:0090231)3.44434824
58protein kinase C signaling (GO:0070528)3.44060276
59regulation of mitotic spindle organization (GO:0060236)3.40740193
60ribonucleoprotein complex biogenesis (GO:0022613)3.40432308
61regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.39404911
62telomere maintenance via semi-conservative replication (GO:0032201)3.39256232
63mitotic sister chromatid cohesion (GO:0007064)3.38251474
64nuclear envelope organization (GO:0006998)3.37109958
65regulation of histone H3-K4 methylation (GO:0051569)3.33523863
66chromatin remodeling at centromere (GO:0031055)3.32379459
67negative regulation of histone methylation (GO:0031061)3.31598322
68regulation of translational fidelity (GO:0006450)3.28330915
69regulation of centrosome cycle (GO:0046605)3.27744808
70DNA replication-independent nucleosome organization (GO:0034724)3.26425792
71DNA replication-independent nucleosome assembly (GO:0006336)3.26425792
72folic acid metabolic process (GO:0046655)3.25871169
73ribosomal large subunit biogenesis (GO:0042273)3.25034021
74protein localization to chromosome (GO:0034502)3.23980782
75CENP-A containing nucleosome assembly (GO:0034080)3.21900834
76regulation of chromosome segregation (GO:0051983)3.21759270
77synapsis (GO:0007129)3.20981111
78establishment of chromosome localization (GO:0051303)3.19400367
79regulation of histone methylation (GO:0031060)3.17393601
80chromatin assembly or disassembly (GO:0006333)3.17368076
81rRNA processing (GO:0006364)3.17154444
82positive regulation of DNA-dependent DNA replication (GO:2000105)3.17134162
83attachment of spindle microtubules to kinetochore (GO:0008608)3.16849694
84chromosome condensation (GO:0030261)3.15638135
85regulation of centriole replication (GO:0046599)3.14870769
86negative regulation of chromosome segregation (GO:0051985)3.14449955
87chromosome segregation (GO:0007059)3.13284905
88spindle checkpoint (GO:0031577)3.11857951
89histone exchange (GO:0043486)3.11587446
90rRNA metabolic process (GO:0016072)3.10135484
91telomere maintenance via recombination (GO:0000722)3.08249133
92spindle assembly checkpoint (GO:0071173)3.07612719
93mitotic recombination (GO:0006312)3.07060314
94negative regulation of mitotic sister chromatid separation (GO:2000816)3.06780398
95negative regulation of mitotic sister chromatid segregation (GO:0033048)3.06780398
96negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.06780398
97negative regulation of sister chromatid segregation (GO:0033046)3.06780398
98protein K6-linked ubiquitination (GO:0085020)3.06111218
99citrulline biosynthetic process (GO:0019240)3.05879022
100regulation of RNA export from nucleus (GO:0046831)3.05157695
101nucleotide-excision repair, DNA gap filling (GO:0006297)3.05078931
102chromatin assembly (GO:0031497)3.04737467
103DNA conformation change (GO:0071103)3.04229244
104regulation of mitotic metaphase/anaphase transition (GO:0030071)3.04142600
105kinetochore organization (GO:0051383)3.03193416
106mitotic spindle checkpoint (GO:0071174)3.03173348
107regulation of double-strand break repair via homologous recombination (GO:0010569)3.02880502
108mitotic spindle assembly checkpoint (GO:0007094)3.02342684
109mitotic G2/M transition checkpoint (GO:0044818)3.02338562
110retinal cone cell development (GO:0046549)3.00728011
111negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.99796182
112sister chromatid cohesion (GO:0007062)2.99316830
113regulation of nucleobase-containing compound transport (GO:0032239)2.98224905
114nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.97375135
115negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.96288721
116regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.96095345
117peptidyl-arginine omega-N-methylation (GO:0035247)2.96086733
118translesion synthesis (GO:0019985)2.95819895
119somatic hypermutation of immunoglobulin genes (GO:0016446)2.95351445
120somatic diversification of immune receptors via somatic mutation (GO:0002566)2.95351445
121telomere maintenance via telomere lengthening (GO:0010833)2.94854393
122positive regulation of mitotic sister chromatid separation (GO:1901970)2.93972155
123positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.93972155
124positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.93972155
125chaperone-mediated protein complex assembly (GO:0051131)2.93917927
126ATP-dependent chromatin remodeling (GO:0043044)2.93292915
127translational initiation (GO:0006413)2.92519354
128* spliceosomal snRNP assembly (GO:0000387)2.91923219
129primitive streak formation (GO:0090009)2.90851541
130establishment of integrated proviral latency (GO:0075713)2.90261187
131centriole replication (GO:0007099)2.89679681
132positive regulation of humoral immune response (GO:0002922)2.88941528
133nucleus organization (GO:0006997)2.87204875
134regulation of mitotic sister chromatid separation (GO:0010965)2.86971914
135regulation of mitotic sister chromatid segregation (GO:0033047)2.86971914
136regulation of sister chromatid segregation (GO:0033045)2.86971914
137negative regulation of DNA repair (GO:0045738)2.85742786

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.95345215
2EZH2_22144423_ChIP-Seq_EOC_Human5.56264434
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.61226008
4* MYC_18555785_ChIP-Seq_MESCs_Mouse4.29755678
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.80641391
6* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.40973605
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.19557167
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.11326774
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.87094608
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.84078926
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.62080018
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.42727053
13BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.38624814
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.35939801
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.35730575
16* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33363486
17* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.30358957
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.26499717
19KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.25704817
20XRN2_22483619_ChIP-Seq_HELA_Human2.24558555
21AR_21909140_ChIP-Seq_LNCAP_Human2.22672160
22JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.21404300
23E2F1_21310950_ChIP-Seq_MCF-7_Human2.14041528
24MYCN_18555785_ChIP-Seq_MESCs_Mouse2.02100204
25POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.00079077
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.99627492
27MYC_22102868_ChIP-Seq_BL_Human1.99543812
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.98264406
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.94802352
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.91678425
31VDR_23849224_ChIP-Seq_CD4+_Human1.90657608
32NANOG_18555785_ChIP-Seq_MESCs_Mouse1.86567078
33SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.86038134
34PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.73637967
35* FOXP3_21729870_ChIP-Seq_TREG_Human1.72483684
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.71897605
37TTF2_22483619_ChIP-Seq_HELA_Human1.67644660
38GABP_19822575_ChIP-Seq_HepG2_Human1.67378157
39DCP1A_22483619_ChIP-Seq_HELA_Human1.64652080
40CIITA_25753668_ChIP-Seq_RAJI_Human1.62874137
41* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.60344050
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60179833
43KDM5A_27292631_Chip-Seq_BREAST_Human1.59947128
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59644409
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.55504307
46STAT3_1855785_ChIP-Seq_MESCs_Mouse1.54708215
47E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.54554194
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.53767838
49TP63_19390658_ChIP-ChIP_HaCaT_Human1.44258408
50TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.42208692
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.41549622
52KLF4_18555785_ChIP-Seq_MESCs_Mouse1.39904058
53HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.38648210
54SALL1_21062744_ChIP-ChIP_HESCs_Human1.36528776
55FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.34783075
56SOX2_18555785_ChIP-Seq_MESCs_Mouse1.33788806
57TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.33072774
58CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.32022479
59RBPJ_22232070_ChIP-Seq_NCS_Mouse1.31469333
60NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.30662334
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.29403737
62CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.28385255
63DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.28128298
64ELK1_19687146_ChIP-ChIP_HELA_Human1.27779260
65* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.27531940
66SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.23714436
67MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.23324848
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.23264860
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21397422
70GATA1_26923725_Chip-Seq_HPCs_Mouse1.19569208
71FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17660758
72* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.17271761
73ELF1_17652178_ChIP-ChIP_JURKAT_Human1.14561348
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.14289487
75KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14053405
76KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.13207986
77KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.13207986
78KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.13207986
79NANOG_21062744_ChIP-ChIP_HESCs_Human1.11920254
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11652970
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11411113
82E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11322979
83STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09808783
84ZNF263_19887448_ChIP-Seq_K562_Human1.09755762
85* TFEB_21752829_ChIP-Seq_HELA_Human1.08561783
86NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.07134873
87HOXB4_20404135_ChIP-ChIP_EML_Mouse1.05962531
88SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.05733543
89ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.05325907
90DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03130610
91TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02436176
92CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.02351806
93CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01716192
94ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.01649187
95TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00793627
96CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99487340
97NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.98951185
98ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97223113
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.90479525
100ERG_20887958_ChIP-Seq_HPC-7_Mouse0.89813635
101VDR_21846776_ChIP-Seq_THP-1_Human0.89129996
102PKCTHETA_26484144_Chip-Seq_BREAST_Human0.87160078
103TCF3_18692474_ChIP-Seq_MESCs_Mouse0.87059086
104SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.86386044
105NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.86302171
106ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.86265273
107ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.84755588
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.84667199
109BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.83087725
110SOX2_18692474_ChIP-Seq_MESCs_Mouse0.79627230
111CHD1_26751641_Chip-Seq_LNCaP_Human0.78883624
112MYC_18940864_ChIP-ChIP_HL60_Human0.77694843
113PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.73645372
114NANOG_16153702_ChIP-ChIP_HESCs_Human0.70253327
115EWS_26573619_Chip-Seq_HEK293_Human0.68537162
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.67205566
117* CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.62843108
118SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.62716358
119TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.61587709
120FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.60948292
121WT1_19549856_ChIP-ChIP_CCG9911_Human0.57743819

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.00456026
2MP0003111_abnormal_nucleus_morphology4.63656046
3MP0010094_abnormal_chromosome_stability4.51457508
4MP0004957_abnormal_blastocyst_morpholog4.21156125
5MP0003077_abnormal_cell_cycle3.91798867
6MP0008057_abnormal_DNA_replication3.76300243
7MP0006292_abnormal_olfactory_placode3.16181019
8MP0008058_abnormal_DNA_repair2.98196403
9MP0001730_embryonic_growth_arrest2.80702691
10MP0003123_paternal_imprinting2.77734708
11MP0008877_abnormal_DNA_methylation2.68171009
12MP0010352_gastrointestinal_tract_polyps2.66897338
13MP0008007_abnormal_cellular_replicative2.64547304
14MP0000350_abnormal_cell_proliferation2.48072936
15MP0010307_abnormal_tumor_latency2.44207393
16MP0008932_abnormal_embryonic_tissue2.41140866
17MP0008789_abnormal_olfactory_epithelium2.39556660
18MP0005394_taste/olfaction_phenotype2.18089320
19MP0005499_abnormal_olfactory_system2.18089320
20MP0005380_embryogenesis_phenotype2.16471940
21MP0001672_abnormal_embryogenesis/_devel2.16471940
22MP0002396_abnormal_hematopoietic_system2.13680873
23MP0005395_other_phenotype2.12008370
24MP0003786_premature_aging1.96755665
25MP0001697_abnormal_embryo_size1.96573277
26MP0003984_embryonic_growth_retardation1.96429010
27MP0002088_abnormal_embryonic_growth/wei1.92702933
28MP0002084_abnormal_developmental_patter1.90529977
29MP0002085_abnormal_embryonic_tissue1.85901026
30MP0005076_abnormal_cell_differentiation1.84872202
31MP0004197_abnormal_fetal_growth/weight/1.80918930
32MP0002080_prenatal_lethality1.80825921
33MP0002086_abnormal_extraembryonic_tissu1.74606383
34MP0003705_abnormal_hypodermis_morpholog1.57993989
35MP0003890_abnormal_embryonic-extraembry1.54112988
36MP0003950_abnormal_plasma_membrane1.52007137
37MP0010030_abnormal_orbit_morphology1.50933817
38MP0000537_abnormal_urethra_morphology1.48824015
39MP0003567_abnormal_fetal_cardiomyocyte1.48806680
40MP0002234_abnormal_pharynx_morphology1.46926722
41MP0002210_abnormal_sex_determination1.46643352
42MP0001293_anophthalmia1.46584018
43MP0004808_abnormal_hematopoietic_stem1.43637070
44MP0003121_genomic_imprinting1.42362668
45MP0000313_abnormal_cell_death1.36147347
46MP0003718_maternal_effect1.35233777
47MP0001145_abnormal_male_reproductive1.32259736
48MP0001929_abnormal_gametogenesis1.32176393
49MP0000490_abnormal_crypts_of1.30826175
50MP0000762_abnormal_tongue_morphology1.29008746
51MP0009672_abnormal_birth_weight1.28922602
52MP0009053_abnormal_anal_canal1.25540862
53MP0002019_abnormal_tumor_incidence1.25163750
54MP0003119_abnormal_digestive_system1.21800784
55MP0003806_abnormal_nucleotide_metabolis1.21706947
56MP0002233_abnormal_nose_morphology1.18519435
57MP0002653_abnormal_ependyma_morphology1.17766096
58MP0000653_abnormal_sex_gland1.08844862
59MP0002160_abnormal_reproductive_system1.08725309
60MP0000566_synostosis1.08187138
61MP0009703_decreased_birth_body1.05106633
62MP0003937_abnormal_limbs/digits/tail_de1.03718130
63MP0000428_abnormal_craniofacial_morphol1.02728558
64MP0009697_abnormal_copulation1.00533171
65MP0003941_abnormal_skin_development0.98670617
66MP0003315_abnormal_perineum_morphology0.97193663
67MP0002111_abnormal_tail_morphology0.96622044
68MP0000703_abnormal_thymus_morphology0.96164972
69MP0002138_abnormal_hepatobiliary_system0.95962780
70MP0010678_abnormal_skin_adnexa0.94409875
71MP0002877_abnormal_melanocyte_morpholog0.94360811
72MP0005397_hematopoietic_system_phenotyp0.92312406
73MP0001545_abnormal_hematopoietic_system0.92312406
74MP0009333_abnormal_splenocyte_physiolog0.91306402
75MP0002092_abnormal_eye_morphology0.91164779
76MP0005501_abnormal_skin_physiology0.91070770
77MP0001849_ear_inflammation0.90733354
78MP0002796_impaired_skin_barrier0.89261965
79MP0000358_abnormal_cell_content/0.88926893
80MP0003698_abnormal_male_reproductive0.88101314
81MP0004264_abnormal_extraembryonic_tissu0.86890998
82MP0005384_cellular_phenotype0.85630460
83MP0001915_intracranial_hemorrhage0.85144035
84MP0009278_abnormal_bone_marrow0.83530336
85MP0003566_abnormal_cell_adhesion0.83156785
86MP0005621_abnormal_cell_physiology0.83070814
87MP0005647_abnormal_sex_gland0.82640491
88MP0004185_abnormal_adipocyte_glucose0.81261380
89MP0005410_abnormal_fertilization0.77769748
90MP0004233_abnormal_muscle_weight0.77651783
91MP0000733_abnormal_muscle_development0.77548207
92MP0005023_abnormal_wound_healing0.77269176
93MP0008770_decreased_survivor_rate0.76799323
94MP0003878_abnormal_ear_physiology0.76202979
95MP0005377_hearing/vestibular/ear_phenot0.76202979
96MP0001661_extended_life_span0.74695602
97MP0003221_abnormal_cardiomyocyte_apopto0.74524320
98MP0000432_abnormal_head_morphology0.74521879
99MP0003935_abnormal_craniofacial_develop0.73312237
100MP0002161_abnormal_fertility/fecundity0.71326469
101MP0003115_abnormal_respiratory_system0.71313723
102MP0005389_reproductive_system_phenotype0.71102377
103MP0002139_abnormal_hepatobiliary_system0.70812500
104MP0004133_heterotaxia0.69310937
105MP0002722_abnormal_immune_system0.68444127
106MP0002697_abnormal_eye_size0.68125101
107MP0001286_abnormal_eye_development0.67954836
108MP0003755_abnormal_palate_morphology0.67484727
109MP0000427_abnormal_hair_cycle0.66828859
110MP0003861_abnormal_nervous_system0.65085341
111MP0002925_abnormal_cardiovascular_devel0.64772372
112MP0002398_abnormal_bone_marrow0.63685597
113MP0002269_muscular_atrophy0.63001860
114MP0000049_abnormal_middle_ear0.62612535
115MP0010368_abnormal_lymphatic_system0.62042865
116MP0008995_early_reproductive_senescence0.61612746
117MP0000579_abnormal_nail_morphology0.60026953
118MP0001119_abnormal_female_reproductive0.59863869
119MP0000689_abnormal_spleen_morphology0.59678003
120MP0010234_abnormal_vibrissa_follicle0.59392380
121MP0003936_abnormal_reproductive_system0.59180743
122MP0002089_abnormal_postnatal_growth/wei0.58600172
123MP0000631_abnormal_neuroendocrine_gland0.56893380
124MP0005360_urolithiasis0.56769333
125MP0003763_abnormal_thymus_physiology0.56297613
126MP0000377_abnormal_hair_follicle0.55211919
127MP0002114_abnormal_axial_skeleton0.55192270
128MP0000477_abnormal_intestine_morphology0.54580915
129MP0000266_abnormal_heart_morphology0.53818853
130MP0003699_abnormal_female_reproductive0.53449315
131MP0000627_abnormal_mammary_gland0.53243558
132MP0002098_abnormal_vibrissa_morphology0.51584414
133MP0003943_abnormal_hepatobiliary_system0.51107705

Predicted human phenotypes

RankGene SetZ-score
1Abnormal gallbladder physiology (HP:0012438)4.14986667
2Cholecystitis (HP:0001082)4.14986667
3Birth length less than 3rd percentile (HP:0003561)4.00432475
4Ependymoma (HP:0002888)3.98011012
5Selective tooth agenesis (HP:0001592)3.78136767
6Abnormality of abdominal situs (HP:0011620)3.77527884
7Abdominal situs inversus (HP:0003363)3.77527884
8Chromsome breakage (HP:0040012)3.67692511
9Impulsivity (HP:0100710)3.58556815
10Reticulocytopenia (HP:0001896)3.56553744
11Chromosomal breakage induced by crosslinking agents (HP:0003221)3.50879738
12Medulloblastoma (HP:0002885)3.41441362
13Colon cancer (HP:0003003)3.37697382
14Nephroblastoma (Wilms tumor) (HP:0002667)3.34374080
15Breast hypoplasia (HP:0003187)3.28986090
16Papillary thyroid carcinoma (HP:0002895)3.16562615
17Embryonal renal neoplasm (HP:0011794)3.14384668
18Abnormality of the anterior horn cell (HP:0006802)3.09113685
19Degeneration of anterior horn cells (HP:0002398)3.09113685
20Abnormality of the labia minora (HP:0012880)3.04398599
21Rhabdomyosarcoma (HP:0002859)2.98115430
22Abnormality of chromosome stability (HP:0003220)2.93859109
23Astrocytoma (HP:0009592)2.87888585
24Abnormality of the astrocytes (HP:0100707)2.87888585
25Patellar aplasia (HP:0006443)2.85958780
26Meckel diverticulum (HP:0002245)2.83185888
27Oligodactyly (hands) (HP:0001180)2.81269500
28Absent radius (HP:0003974)2.77567547
29Absent thumb (HP:0009777)2.74910578
30Abnormality of the preputium (HP:0100587)2.71108248
31Glioma (HP:0009733)2.70158116
32Aplasia/Hypoplasia of the patella (HP:0006498)2.70010951
33Carpal bone hypoplasia (HP:0001498)2.68650049
34Abnormality of the ileum (HP:0001549)2.64393440
35Oral leukoplakia (HP:0002745)2.61372311
36Proximal placement of thumb (HP:0009623)2.61098825
37Septo-optic dysplasia (HP:0100842)2.60016166
38Aplasia/Hypoplasia of the uvula (HP:0010293)2.59063648
39Deviation of the thumb (HP:0009603)2.57778632
40Absent forearm bone (HP:0003953)2.56383028
41Aplasia involving forearm bones (HP:0009822)2.56383028
42Lip pit (HP:0100267)2.54731040
43Ectopic kidney (HP:0000086)2.54721208
44Aplasia/Hypoplasia of the fovea (HP:0008060)2.54679394
45Hypoplasia of the fovea (HP:0007750)2.54679394
46Microglossia (HP:0000171)2.53155267
47Abnormality of cells of the erythroid lineage (HP:0012130)2.52816987
48Capillary hemangiomas (HP:0005306)2.52197999
4911 pairs of ribs (HP:0000878)2.48018792
50Prominent nose (HP:0000448)2.47982494
51Rough bone trabeculation (HP:0100670)2.47265363
52Cerebral hypomyelination (HP:0006808)2.46773550
53Abnormal number of incisors (HP:0011064)2.46120206
54Increased nuchal translucency (HP:0010880)2.45605739
55Gonadotropin excess (HP:0000837)2.45265639
56Basal cell carcinoma (HP:0002671)2.43807526
57Agnosia (HP:0010524)2.43711262
58Missing ribs (HP:0000921)2.40619747
59Neoplasm of striated muscle (HP:0009728)2.40344878
60Neoplasm of the pancreas (HP:0002894)2.40189777
61Osteomalacia (HP:0002749)2.38096245
62Urethral obstruction (HP:0000796)2.36731755
63Male infertility (HP:0003251)2.35916937
64Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.34877592
65Abnormal number of erythroid precursors (HP:0012131)2.33557044
66Myelodysplasia (HP:0002863)2.33469247
67Duodenal stenosis (HP:0100867)2.33466663
68Small intestinal stenosis (HP:0012848)2.33466663
69Neoplasm of the oral cavity (HP:0100649)2.33202038
70Abnormality of the septum pellucidum (HP:0007375)2.30026150
71Absent septum pellucidum (HP:0001331)2.29749659
72Premature ovarian failure (HP:0008209)2.27163507
73Oligodactyly (HP:0012165)2.26968964
74Sloping forehead (HP:0000340)2.24826719
75Atresia of the external auditory canal (HP:0000413)2.23687270
76Anterior segment dysgenesis (HP:0007700)2.23197777
77Hypokinesia (HP:0002375)2.22586607
78Horseshoe kidney (HP:0000085)2.22475435
79Supernumerary spleens (HP:0009799)2.20807296
80Hypergonadotropic hypogonadism (HP:0000815)2.20619865
81Ureteral duplication (HP:0000073)2.20278328
82Trismus (HP:0000211)2.19638330
83Pelvic girdle muscle weakness (HP:0003749)2.18898682
84Median cleft lip (HP:0000161)2.16977438
85Cafe-au-lait spot (HP:0000957)2.15905527
86Abnormality of the carotid arteries (HP:0005344)2.15883140
87Aplasia/hypoplasia of the humerus (HP:0006507)2.13282605
88Choanal atresia (HP:0000453)2.12964218
89Short 4th metacarpal (HP:0010044)2.11793656
90Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.11793656
91Hypophosphatemic rickets (HP:0004912)2.11272855
92Duplicated collecting system (HP:0000081)2.11159424
93Squamous cell carcinoma (HP:0002860)2.10307939
94Sparse lateral eyebrow (HP:0005338)2.08860640
95Biliary tract neoplasm (HP:0100574)2.08019942
96Abnormality of the fovea (HP:0000493)2.06696253
97Tracheoesophageal fistula (HP:0002575)2.05762368
98Progressive muscle weakness (HP:0003323)2.02510057
99Abnormality of chromosome segregation (HP:0002916)2.02461141
100Abnormality of the calcaneus (HP:0008364)2.02407030
101Facial hemangioma (HP:0000329)2.01155675
102Spinal cord compression (HP:0002176)2.00232439
103Bone marrow hypocellularity (HP:0005528)1.99893409
104Short thumb (HP:0009778)1.97189115
105Premature graying of hair (HP:0002216)1.95862747
106Abnormality of the duodenum (HP:0002246)1.94153905
107Progressive external ophthalmoplegia (HP:0000590)1.93835004
108Short humerus (HP:0005792)1.93829941
109Heterotopia (HP:0002282)1.92906710
110Abnormality of the renal collecting system (HP:0004742)1.92167198
111Thyroid carcinoma (HP:0002890)1.91878677
112Sensory axonal neuropathy (HP:0003390)1.91764218
113Cortical dysplasia (HP:0002539)1.91509677
114Spinal muscular atrophy (HP:0007269)1.91095789
115Dysmetric saccades (HP:0000641)1.90926443
116Clubbing of toes (HP:0100760)1.89983329
117Abnormality of pyrimidine metabolism (HP:0004353)1.89804734
118Abnormality of the salivary glands (HP:0010286)1.89769085
119Macrocytic anemia (HP:0001972)1.88789299
120Stillbirth (HP:0003826)1.87767738
121Abnormality of the phalanges of the hallux (HP:0010057)1.87156410
122Pallor (HP:0000980)1.87124854
123High pitched voice (HP:0001620)1.85808836
124Abnormality of DNA repair (HP:0003254)1.85710633
125Atrophy/Degeneration involving motor neurons (HP:0007373)1.85199822
126Poikiloderma (HP:0001029)1.84953125
127Aplasia/Hypoplasia of the sternum (HP:0006714)1.84314058
128Microvesicular hepatic steatosis (HP:0001414)1.84302340
129Multiple enchondromatosis (HP:0005701)1.83355355
130Leiomyosarcoma (HP:0100243)1.83279433
131Uterine leiomyosarcoma (HP:0002891)1.83279433
132Embryonal neoplasm (HP:0002898)1.83046795
133Overlapping toe (HP:0001845)1.83043361
134Entropion (HP:0000621)1.81421209
135Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.79117761
136Bifid tongue (HP:0010297)1.78921938
137Secondary amenorrhea (HP:0000869)1.77826510
138Triphalangeal thumb (HP:0001199)1.77587904
139Cellular immunodeficiency (HP:0005374)1.77192645
140Volvulus (HP:0002580)1.77149694
141Short tibia (HP:0005736)1.77064597
142Sandal gap (HP:0001852)1.76478618
143Hypoplasia of the capital femoral epiphysis (HP:0003090)1.75974451
144Abnormality of the lower motor neuron (HP:0002366)1.75870464
145Abnormal lung lobation (HP:0002101)1.75046223
146Malignant gastrointestinal tract tumors (HP:0006749)1.73104053
147Gastrointestinal carcinoma (HP:0002672)1.73104053
148Microretrognathia (HP:0000308)1.72987168
149Amaurosis fugax (HP:0100576)1.72617303
150Lower limb hyperreflexia (HP:0002395)1.72606016
151Facial cleft (HP:0002006)1.71715847
152Shoulder girdle muscle weakness (HP:0003547)1.71405101
153Long eyelashes (HP:0000527)1.70450105
154Azoospermia (HP:0000027)1.68099792
155Cleft eyelid (HP:0000625)1.65748748
156Duplication of thumb phalanx (HP:0009942)1.62387852
157Posterior subcapsular cataract (HP:0007787)1.61828310

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.07101276
2WEE14.05517745
3BUB13.80940583
4MAP3K93.48938879
5NEK23.16738895
6CDK123.02464406
7TSSK62.74403501
8ARAF2.65967563
9PBK2.61459176
10EEF2K2.56786695
11TTK2.51237753
12BRSK22.32542631
13MAP3K132.31274816
14NEK12.24959118
15SRPK12.08549345
16EIF2AK12.08427344
17EPHA21.95170742
18NEK61.92314388
19PLK41.92123812
20PLK11.90011622
21MET1.80487067
22RPS6KB21.77150974
23ATR1.73410415
24MST41.72939215
25PASK1.71922392
26PLK31.71081721
27MKNK11.63474300
28CDK71.63049241
29SCYL21.62256563
30CDK41.60865763
31PNCK1.60112573
32CHEK21.59408845
33AURKB1.57711114
34PKN21.53037293
35CHEK11.50870794
36PDK31.49584010
37PDK41.49584010
38TLK11.48681610
39MKNK21.45006408
40ACVR1B1.41311597
41ALK1.39627376
42ZAK1.36296740
43MAP3K101.35237467
44DYRK31.34881286
45MAP3K81.34789654
46TRIM281.34002371
47STK241.33371596
48BRSK11.33244217
49ERBB41.33239187
50TESK21.32120933
51BRD41.29792398
52RAF11.20312835
53SMG11.18784315
54NME21.14726091
55EIF2AK31.13612987
56RPS6KA41.12800427
57AURKA1.12718318
58STK101.10310072
59LATS21.08601538
60VRK11.04683860
61MOS1.04533565
62ATM1.04059769
63STK31.03287331
64MTOR1.01184461
65CDK21.00824340
66FLT30.99908325
67STK160.96068801
68PAK40.94277082
69STK40.93599064
70LATS10.90962113
71TGFBR10.90837687
72ICK0.90393929
73KSR20.89905048
74CDK80.87320034
75CDK60.86002513
76PIM10.81859826
77PDK20.81011982
78STK38L0.80004444
79TESK10.79733677
80TRIB30.77697793
81EIF2AK20.75403736
82KSR10.73223221
83TNIK0.72269107
84VRK20.71863567
85CDK10.71303942
86PAK10.70220296
87CSNK1G10.68831348
88CSNK2A20.67582667
89NUAK10.67247488
90PAK20.66147044
91PTK20.65459376
92CSNK1E0.64508876
93MELK0.64041347
94CAMK1D0.63248206
95AKT30.61053763
96MST1R0.59149334
97TTN0.58463033
98MAP2K30.57274765
99NME10.57218936
100DMPK0.56864189
101CCNB10.56707952
102FGFR10.55492611
103BMPR1B0.55488719
104CAMK1G0.53778701
105CLK10.53457830
106AKT20.53135752
107LRRK20.50680476
108TAF10.48822862
109PRKDC0.48118383
110PRKCI0.48100536
111CSNK2A10.48020256
112NEK90.46649980
113CSNK1D0.44204026
114RPS6KA50.40479339
115MARK30.39791529
116MAP4K10.37327521
117CSNK1G30.35563090
118MAPKAPK30.34389757
119MAP3K30.32871648
120MAPK140.32776861
121PIM20.28299959
122PRKD30.27770600
123CSNK1A1L0.27672701
124GSK3B0.26148758
125RPS6KA10.26110815
126CDK90.25221881
127MAPK10.25092727
128BRAF0.25016277
129RPS6KB10.24897766
130AKT10.22412527
131BMX0.21259237
132PTK60.17084442
133MAP2K20.16568647

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.36228622
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.25179076
3Mismatch repair_Homo sapiens_hsa034303.75177845
4* RNA transport_Homo sapiens_hsa030133.62515081
5Spliceosome_Homo sapiens_hsa030403.26233341
6One carbon pool by folate_Homo sapiens_hsa006703.19557216
7RNA polymerase_Homo sapiens_hsa030202.94483548
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.92093228
9Cell cycle_Homo sapiens_hsa041102.86102095
10Base excision repair_Homo sapiens_hsa034102.69166066
11Nucleotide excision repair_Homo sapiens_hsa034202.60074566
12Homologous recombination_Homo sapiens_hsa034402.56810140
13Ribosome_Homo sapiens_hsa030102.41715693
14Proteasome_Homo sapiens_hsa030502.26742225
15Fanconi anemia pathway_Homo sapiens_hsa034602.20002435
16mRNA surveillance pathway_Homo sapiens_hsa030152.16709087
17Pyrimidine metabolism_Homo sapiens_hsa002402.16578736
18Vitamin B6 metabolism_Homo sapiens_hsa007502.15126710
19Non-homologous end-joining_Homo sapiens_hsa034502.00684116
20RNA degradation_Homo sapiens_hsa030181.90737320
21Basal transcription factors_Homo sapiens_hsa030221.78919327
22p53 signaling pathway_Homo sapiens_hsa041151.64071325
23Systemic lupus erythematosus_Homo sapiens_hsa053221.62710727
24Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.31862842
25Oocyte meiosis_Homo sapiens_hsa041141.24620970
26Epstein-Barr virus infection_Homo sapiens_hsa051691.23734228
27Viral carcinogenesis_Homo sapiens_hsa052031.23071047
28Selenocompound metabolism_Homo sapiens_hsa004501.21087130
29Biosynthesis of amino acids_Homo sapiens_hsa012301.20836484
30Purine metabolism_Homo sapiens_hsa002301.18564187
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.18116392
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.17970082
33Pentose phosphate pathway_Homo sapiens_hsa000301.13622840
34Antigen processing and presentation_Homo sapiens_hsa046121.11469708
35Pyruvate metabolism_Homo sapiens_hsa006201.07834871
36Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.04704344
37Ovarian steroidogenesis_Homo sapiens_hsa049131.02847726
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.01481082
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.96161184
40MicroRNAs in cancer_Homo sapiens_hsa052060.86816115
41HTLV-I infection_Homo sapiens_hsa051660.86091649
42Herpes simplex infection_Homo sapiens_hsa051680.84765386
43Drug metabolism - other enzymes_Homo sapiens_hsa009830.82958721
44Small cell lung cancer_Homo sapiens_hsa052220.74421191
45Propanoate metabolism_Homo sapiens_hsa006400.73650718
46Thyroid cancer_Homo sapiens_hsa052160.73316869
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.72900185
48Fatty acid elongation_Homo sapiens_hsa000620.72635884
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.72474014
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.71326059
51Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.71242547
52Hippo signaling pathway_Homo sapiens_hsa043900.70590120
53Carbon metabolism_Homo sapiens_hsa012000.69160696
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66420907
55Central carbon metabolism in cancer_Homo sapiens_hsa052300.64925105
56Gap junction_Homo sapiens_hsa045400.63382916
57Basal cell carcinoma_Homo sapiens_hsa052170.62844471
58Alcoholism_Homo sapiens_hsa050340.60992180
59mTOR signaling pathway_Homo sapiens_hsa041500.60273706
60Folate biosynthesis_Homo sapiens_hsa007900.58936962
61Dorso-ventral axis formation_Homo sapiens_hsa043200.58083474
62Inositol phosphate metabolism_Homo sapiens_hsa005620.57115071
63Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56957173
64Circadian rhythm_Homo sapiens_hsa047100.56129266
65Transcriptional misregulation in cancer_Homo sapiens_hsa052020.55432751
66TGF-beta signaling pathway_Homo sapiens_hsa043500.53948885
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.52794337
68Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.52525798
69Notch signaling pathway_Homo sapiens_hsa043300.52003304
70Lysine degradation_Homo sapiens_hsa003100.51412425
71Steroid biosynthesis_Homo sapiens_hsa001000.51280361
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.49099078
73Arginine biosynthesis_Homo sapiens_hsa002200.48157007
74Chronic myeloid leukemia_Homo sapiens_hsa052200.48091604
75Sulfur relay system_Homo sapiens_hsa041220.47779691
76Fructose and mannose metabolism_Homo sapiens_hsa000510.45194164
77Colorectal cancer_Homo sapiens_hsa052100.44807180
78Adherens junction_Homo sapiens_hsa045200.44620204
79Bladder cancer_Homo sapiens_hsa052190.44374450
80HIF-1 signaling pathway_Homo sapiens_hsa040660.42288433
81Hedgehog signaling pathway_Homo sapiens_hsa043400.41883646
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37801601
83Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.36301279
84Legionellosis_Homo sapiens_hsa051340.36221105
85Apoptosis_Homo sapiens_hsa042100.36154875
86Arginine and proline metabolism_Homo sapiens_hsa003300.35066479
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34474787
88Protein export_Homo sapiens_hsa030600.33532557
89ErbB signaling pathway_Homo sapiens_hsa040120.32353529
90Pancreatic cancer_Homo sapiens_hsa052120.32256650
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.32047749
92Acute myeloid leukemia_Homo sapiens_hsa052210.31557718
93Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.31274779
94Insulin signaling pathway_Homo sapiens_hsa049100.30399221
95Pathways in cancer_Homo sapiens_hsa052000.29713427
96Prostate cancer_Homo sapiens_hsa052150.29564088
97Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28460842
98Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28247419
99Hepatitis B_Homo sapiens_hsa051610.27071185
100Non-small cell lung cancer_Homo sapiens_hsa052230.26701488
101Glutathione metabolism_Homo sapiens_hsa004800.26082257
102Caffeine metabolism_Homo sapiens_hsa002320.25798088
103Tight junction_Homo sapiens_hsa045300.25643112
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.25373804
105Galactose metabolism_Homo sapiens_hsa000520.24347498
106Huntingtons disease_Homo sapiens_hsa050160.24142789
107Viral myocarditis_Homo sapiens_hsa054160.22620284
108Wnt signaling pathway_Homo sapiens_hsa043100.21075328
109Proteoglycans in cancer_Homo sapiens_hsa052050.20283266
110Olfactory transduction_Homo sapiens_hsa047400.20056293
111Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.19745450
112Renal cell carcinoma_Homo sapiens_hsa052110.19622066
113N-Glycan biosynthesis_Homo sapiens_hsa005100.19483240
114FoxO signaling pathway_Homo sapiens_hsa040680.19195630
115Renin-angiotensin system_Homo sapiens_hsa046140.18794050
116Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.18788842
117AMPK signaling pathway_Homo sapiens_hsa041520.18420590
118Endometrial cancer_Homo sapiens_hsa052130.17911010
119Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.16731086
120Measles_Homo sapiens_hsa051620.15914727
121Influenza A_Homo sapiens_hsa051640.14497074
122NF-kappa B signaling pathway_Homo sapiens_hsa040640.11618015
123Melanoma_Homo sapiens_hsa052180.11060877
124Glucagon signaling pathway_Homo sapiens_hsa049220.10856608
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.09690739

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