GFOD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.99523205
2pyrimidine nucleobase catabolic process (GO:0006208)5.43873775
3serotonin metabolic process (GO:0042428)4.67878968
4primary amino compound metabolic process (GO:1901160)4.35698330
5opioid receptor signaling pathway (GO:0038003)4.06808980
6gamma-aminobutyric acid transport (GO:0015812)3.94217357
7indolalkylamine metabolic process (GO:0006586)3.85517298
8behavioral response to nicotine (GO:0035095)3.82605520
9nucleobase catabolic process (GO:0046113)3.67830428
10regulation of timing of cell differentiation (GO:0048505)3.60750244
11limb bud formation (GO:0060174)3.60513350
12indole-containing compound metabolic process (GO:0042430)3.59519295
13uterus development (GO:0060065)3.58440309
14regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.52590213
15kynurenine metabolic process (GO:0070189)3.50870648
16kidney morphogenesis (GO:0060993)3.48301341
17L-fucose metabolic process (GO:0042354)3.46701165
18L-fucose catabolic process (GO:0042355)3.46701165
19fucose catabolic process (GO:0019317)3.46701165
20neurofilament cytoskeleton organization (GO:0060052)3.42577803
21cerebral cortex radially oriented cell migration (GO:0021799)3.42501421
22nonmotile primary cilium assembly (GO:0035058)3.38370338
23regulation of short-term neuronal synaptic plasticity (GO:0048172)3.36543523
24negative regulation of synaptic transmission, GABAergic (GO:0032229)3.35359275
25epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.34855201
26indole-containing compound catabolic process (GO:0042436)3.33474798
27indolalkylamine catabolic process (GO:0046218)3.33474798
28tryptophan catabolic process (GO:0006569)3.33474798
29regulation of development, heterochronic (GO:0040034)3.32753778
30facial nerve structural organization (GO:0021612)3.31560889
31cellular ketone body metabolic process (GO:0046950)3.30920258
32regulation of alternative mRNA splicing, via spliceosome (GO:0000381)3.30002104
33G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.29566804
34photoreceptor cell maintenance (GO:0045494)3.26916331
35protein polyglutamylation (GO:0018095)3.24092323
36dendritic spine morphogenesis (GO:0060997)3.23311575
37ionotropic glutamate receptor signaling pathway (GO:0035235)3.22323769
38central nervous system projection neuron axonogenesis (GO:0021952)3.19757809
39vocalization behavior (GO:0071625)3.16194818
40sympathetic nervous system development (GO:0048485)3.16128718
41cranial nerve structural organization (GO:0021604)3.15130368
42regulation of interferon-beta biosynthetic process (GO:0045357)3.14470109
43protein localization to cilium (GO:0061512)3.13548379
44glutamate receptor signaling pathway (GO:0007215)3.11691276
45epithelial cilium movement (GO:0003351)3.11653352
46neuron cell-cell adhesion (GO:0007158)3.04772148
47regulation of non-canonical Wnt signaling pathway (GO:2000050)3.03782418
48neuronal action potential (GO:0019228)3.03389463
49superoxide anion generation (GO:0042554)3.02954180
50axoneme assembly (GO:0035082)3.02920329
51membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.02548187
52transmission of nerve impulse (GO:0019226)3.02498400
53serotonin receptor signaling pathway (GO:0007210)3.02462660
54synaptic transmission, glutamatergic (GO:0035249)3.01361639
55negative regulation of oligodendrocyte differentiation (GO:0048715)3.01014711
56cilium or flagellum-dependent cell motility (GO:0001539)3.00610513
57synaptic vesicle maturation (GO:0016188)3.00375120
58positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.99559789
59positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)2.99524025
60cAMP catabolic process (GO:0006198)2.98642394
61adenine nucleotide transport (GO:0051503)2.97227636
62positive regulation of heat generation (GO:0031652)2.94674494
63synapse assembly (GO:0007416)2.94198173
64regulation of fever generation (GO:0031620)2.90584554
65dendrite development (GO:0016358)2.90328823
66synaptic transmission, cholinergic (GO:0007271)2.89960691
67negative regulation of telomere maintenance (GO:0032205)2.89074446
68ketone body metabolic process (GO:1902224)2.88580135
69negative regulation of keratinocyte proliferation (GO:0010839)2.86484633
70forebrain neuron differentiation (GO:0021879)2.86360645
71cerebellar Purkinje cell differentiation (GO:0021702)2.84874831
72reflex (GO:0060004)2.82823375
73cranial nerve morphogenesis (GO:0021602)2.82518517
74purine ribonucleotide transport (GO:0015868)2.82437964
75startle response (GO:0001964)2.82043792
76negative regulation of cytosolic calcium ion concentration (GO:0051481)2.80437471
77cell migration in hindbrain (GO:0021535)2.79770405
78neuronal action potential propagation (GO:0019227)2.79241648
79neurotransmitter metabolic process (GO:0042133)2.79106377
80kinetochore assembly (GO:0051382)2.78089866
81hindbrain development (GO:0030902)2.76814117
82regulation of action potential (GO:0098900)2.76787166
83detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.76716241
84cilium movement (GO:0003341)2.76480562
85tryptophan metabolic process (GO:0006568)2.75279565
86membrane depolarization during action potential (GO:0086010)2.74928334
87glycerophospholipid catabolic process (GO:0046475)2.73231230
88histamine secretion (GO:0001821)2.72732927
89negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.72583931
90mesenchymal cell differentiation involved in renal system development (GO:2001012)2.71873376
91mesenchymal cell differentiation involved in kidney development (GO:0072161)2.71873376
92proximal/distal pattern formation (GO:0009954)2.69038947
93behavioral response to ethanol (GO:0048149)2.67479721
94regulation of telomere maintenance (GO:0032204)2.66520109
95somite development (GO:0061053)2.65816766
96cyclic nucleotide catabolic process (GO:0009214)2.65716301
97negative regulation of axon guidance (GO:1902668)2.65375841
98adult walking behavior (GO:0007628)2.64626561
99neurotransmitter-gated ion channel clustering (GO:0072578)2.63937382
100spinal cord motor neuron differentiation (GO:0021522)2.63067407
101atrial cardiac muscle cell action potential (GO:0086014)2.62991799
102regulation of microtubule-based movement (GO:0060632)2.62772401
103protein K11-linked deubiquitination (GO:0035871)2.62763318
104response to auditory stimulus (GO:0010996)2.62758829
105negative regulation of mast cell activation (GO:0033004)2.62057817
106neuron-neuron synaptic transmission (GO:0007270)2.61685217
107microtubule depolymerization (GO:0007019)2.61611778
108head development (GO:0060322)2.61463306
109histone H2B ubiquitination (GO:0033523)2.60615024
110regulation of synapse maturation (GO:0090128)2.59703247
111neuromuscular synaptic transmission (GO:0007274)2.58687855
112regulation of neurotransmitter levels (GO:0001505)2.58416189
113negative regulation of stem cell proliferation (GO:2000647)2.57966187
114DNA methylation involved in gamete generation (GO:0043046)2.55666286
115neurotransmitter secretion (GO:0007269)2.55399777
116phosphatidylserine acyl-chain remodeling (GO:0036150)2.55251341
117alanine transport (GO:0032328)2.54628505
118proline transport (GO:0015824)2.54015234
119postsynaptic membrane organization (GO:0001941)2.53765615
120generation of neurons (GO:0048699)2.53036157
121positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.51758851
122ganglion development (GO:0061548)2.51559294
123auditory behavior (GO:0031223)2.51415925
124retinal cone cell development (GO:0046549)2.50899741
125retina layer formation (GO:0010842)2.49526000
126regulation of respiratory system process (GO:0044065)2.49105335
127positive regulation of action potential (GO:0045760)2.48632200
128cilium organization (GO:0044782)2.47898448
129sperm motility (GO:0030317)2.47324516
130glycosphingolipid biosynthetic process (GO:0006688)2.47053894
131regulation of cilium movement (GO:0003352)2.46677496
132detection of light stimulus involved in visual perception (GO:0050908)2.45619908
133detection of light stimulus involved in sensory perception (GO:0050962)2.45619908
134central nervous system neuron axonogenesis (GO:0021955)2.45581724
135neuron fate determination (GO:0048664)2.45564086
136water-soluble vitamin biosynthetic process (GO:0042364)2.45506400
137cranial nerve development (GO:0021545)2.45460642
138regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.45070802
139cilium assembly (GO:0042384)2.45039183
140regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.44843546
141regulation of mitotic spindle checkpoint (GO:1903504)2.44843546
142cilium morphogenesis (GO:0060271)2.44306458
143olfactory bulb development (GO:0021772)2.43462693
144neuron remodeling (GO:0016322)2.43258479
145cell proliferation in forebrain (GO:0021846)2.42495449
146regulation of neurotransmitter uptake (GO:0051580)2.41134355
147oxidative demethylation (GO:0070989)2.41085733
148regulation of mitochondrial translation (GO:0070129)2.40707483
149regulation of calcium ion-dependent exocytosis (GO:0017158)2.40601550
150negative regulation of myoblast differentiation (GO:0045662)2.38929641
151regulation of chemokine-mediated signaling pathway (GO:0070099)2.38237382
152regulation of keratinocyte proliferation (GO:0010837)2.38216772
153retinal ganglion cell axon guidance (GO:0031290)2.37999834
154protein localization to synapse (GO:0035418)2.37166017
155cornea development in camera-type eye (GO:0061303)2.37147370
156positive regulation of synapse assembly (GO:0051965)2.37036109
157cellular response to virus (GO:0098586)2.36228223
158regulation of synapse assembly (GO:0051963)2.36050789
159positive regulation of protein homodimerization activity (GO:0090073)2.34822209
160activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.34649564
161axonal fasciculation (GO:0007413)2.34605976
162nucleotide transmembrane transport (GO:1901679)2.34483863
163presynaptic membrane assembly (GO:0097105)2.32509960
164neuron recognition (GO:0008038)2.30784377
165phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.30038030
166hippocampus development (GO:0021766)2.29931190
167negative regulation of translation, ncRNA-mediated (GO:0040033)2.29550536
168regulation of translation, ncRNA-mediated (GO:0045974)2.29550536
169negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.29550536
170dopaminergic neuron differentiation (GO:0071542)2.29527386
171midbrain development (GO:0030901)2.29356642
172poly(A)+ mRNA export from nucleus (GO:0016973)2.28943988
173superoxide metabolic process (GO:0006801)2.27498992
174inner ear receptor stereocilium organization (GO:0060122)2.27430157
175presynaptic membrane organization (GO:0097090)2.26853749
176mechanosensory behavior (GO:0007638)2.26081332
177regulation of heat generation (GO:0031650)2.24631165
178female gonad development (GO:0008585)2.24520681
179cerebral cortex cell migration (GO:0021795)2.23654613
180mitochondrion morphogenesis (GO:0070584)2.23516817
181negative regulation of axon extension involved in axon guidance (GO:0048843)2.22984700
182neural crest cell development (GO:0014032)2.22722050

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.86755932
2GBX2_23144817_ChIP-Seq_PC3_Human3.87565436
3ZNF274_21170338_ChIP-Seq_K562_Hela3.40180149
4BMI1_23680149_ChIP-Seq_NPCS_Mouse3.03508422
5CBX2_27304074_Chip-Seq_ESCs_Mouse2.74409530
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.62564251
7TP63_19390658_ChIP-ChIP_HaCaT_Human2.60225202
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.55814460
9VDR_22108803_ChIP-Seq_LS180_Human2.50562329
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.48194339
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41131314
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.40413898
13BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.39750854
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.38727184
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.37815551
16PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.33223633
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.11498832
18DROSHA_22980978_ChIP-Seq_HELA_Human2.10170706
19RNF2_18974828_ChIP-Seq_MESCs_Mouse2.10096537
20EZH2_18974828_ChIP-Seq_MESCs_Mouse2.10096537
21JARID2_20075857_ChIP-Seq_MESCs_Mouse2.08945653
22TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.07992504
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.06526283
24SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.00136455
25RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.99203541
26TAF15_26573619_Chip-Seq_HEK293_Human1.97728859
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97508309
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.97275298
29RNF2_27304074_Chip-Seq_NSC_Mouse1.96646798
30FLI1_27457419_Chip-Seq_LIVER_Mouse1.93588283
31SUZ12_27294783_Chip-Seq_NPCs_Mouse1.92697343
32P300_19829295_ChIP-Seq_ESCs_Human1.91646063
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.88408258
34POU5F1_16153702_ChIP-ChIP_HESCs_Human1.87099794
35POU3F2_20337985_ChIP-ChIP_501MEL_Human1.83089230
36IGF1R_20145208_ChIP-Seq_DFB_Human1.82367461
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.81808934
38EZH2_27294783_Chip-Seq_ESCs_Mouse1.80268902
39PCGF2_27294783_Chip-Seq_NPCs_Mouse1.78239964
40NFE2_27457419_Chip-Seq_LIVER_Mouse1.76556264
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.74013928
42TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.71815248
43REST_18959480_ChIP-ChIP_MESCs_Mouse1.71508778
44NANOG_18555785_Chip-Seq_ESCs_Mouse1.68742523
45SUZ12_27294783_Chip-Seq_ESCs_Mouse1.67676137
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.66904410
47EWS_26573619_Chip-Seq_HEK293_Human1.64239693
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.64201228
49E2F1_18555785_Chip-Seq_ESCs_Mouse1.62744842
50EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.62148417
51ER_23166858_ChIP-Seq_MCF-7_Human1.60927225
52CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.60113501
53TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59733263
54POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.59733263
55* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.57956476
56SUZ12_18555785_Chip-Seq_ESCs_Mouse1.56234735
57REST_21632747_ChIP-Seq_MESCs_Mouse1.52863416
58CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52012800
59SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.51869575
60ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.50291889
61EZH2_27294783_Chip-Seq_NPCs_Mouse1.47633706
62P53_22387025_ChIP-Seq_ESCs_Mouse1.47629584
63CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47098935
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46229270
65STAT3_18555785_Chip-Seq_ESCs_Mouse1.45899100
66EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.45824374
67MTF2_20144788_ChIP-Seq_MESCs_Mouse1.43570899
68AR_21572438_ChIP-Seq_LNCaP_Human1.43549477
69CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43161137
70UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.40504617
71PIAS1_25552417_ChIP-Seq_VCAP_Human1.38860572
72RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37761337
73CMYC_18555785_Chip-Seq_ESCs_Mouse1.37478821
74SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37291792
75TCF4_23295773_ChIP-Seq_U87_Human1.36129868
76CDX2_19796622_ChIP-Seq_MESCs_Mouse1.35972779
77IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35566488
78CBP_20019798_ChIP-Seq_JUKART_Human1.35566488
79NMYC_18555785_Chip-Seq_ESCs_Mouse1.34005651
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33754269
81MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32633640
82TP53_22573176_ChIP-Seq_HFKS_Human1.32240126
83HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.31850498
84RUNX1_27457419_Chip-Seq_LIVER_Mouse1.31527783
85TCF4_18268006_ChIP-ChIP_LS174T_Human1.31228642
86BCAT_22108803_ChIP-Seq_LS180_Human1.31112515
87SMAD4_21799915_ChIP-Seq_A2780_Human1.30265063
88SALL1_21062744_ChIP-ChIP_HESCs_Human1.30130582
89SOX2_18555785_Chip-Seq_ESCs_Mouse1.28842844
90CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.28515567
91SMAD_19615063_ChIP-ChIP_OVARY_Human1.27972287
92P300_18555785_Chip-Seq_ESCs_Mouse1.27222611
93OCT4_18555785_Chip-Seq_ESCs_Mouse1.19779789
94IRF1_19129219_ChIP-ChIP_H3396_Human1.19391065
95TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18911579
96ZFX_18555785_Chip-Seq_ESCs_Mouse1.17424494
97SMAD3_21741376_ChIP-Seq_EPCs_Human1.16483189
98ESRRB_18555785_Chip-Seq_ESCs_Mouse1.16225551
99ETV2_25802403_ChIP-Seq_MESCs_Mouse1.15593284
100TAL1_26923725_Chip-Seq_HPCs_Mouse1.14691024
101GATA1_26923725_Chip-Seq_HPCs_Mouse1.13448357
102KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13105829
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.12834614
104TCF4_22108803_ChIP-Seq_LS180_Human1.12080162
105PU1_27457419_Chip-Seq_LIVER_Mouse1.11951154
106NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09587888
107PRDM14_20953172_ChIP-Seq_ESCs_Human1.09552558
108RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.08975419
109KLF4_18555785_Chip-Seq_ESCs_Mouse1.08933094
110CTCF_18555785_Chip-Seq_ESCs_Mouse1.08205033
111FUS_26573619_Chip-Seq_HEK293_Human1.08201404
112GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07733451
113JUN_21703547_ChIP-Seq_K562_Human1.05873685
114RUNX2_22187159_ChIP-Seq_PCA_Human1.05718018
115SMAD1_18555785_Chip-Seq_ESCs_Mouse1.05472446
116SMAD4_21741376_ChIP-Seq_EPCs_Human1.05431299
117OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04681001
118NCOR_22424771_ChIP-Seq_293T_Human1.04416237
119RING1B_27294783_Chip-Seq_NPCs_Mouse1.03289220
120FLI1_21867929_ChIP-Seq_TH2_Mouse1.03159350
121SOX2_21211035_ChIP-Seq_LN229_Gbm1.02254625
122TP53_18474530_ChIP-ChIP_U2OS_Human1.02006392
123AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01836442
124SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01625360
125TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.01577250
126STAT3_23295773_ChIP-Seq_U87_Human1.01096596
127OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00695803
128SMAD3_21741376_ChIP-Seq_ESCs_Human1.00164951
129FOXA1_25329375_ChIP-Seq_VCAP_Human1.00138424
130FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00138424
131AR_25329375_ChIP-Seq_VCAP_Human0.98642141
132TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98540632
133RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.96194940
134ERA_21632823_ChIP-Seq_H3396_Human0.95618505
135SOX2_19829295_ChIP-Seq_ESCs_Human0.92900150
136NANOG_19829295_ChIP-Seq_ESCs_Human0.92900150
137AR_19668381_ChIP-Seq_PC3_Human0.92579243
138KDM2B_26808549_Chip-Seq_REH_Human0.91407027
139TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.91395465
140GATA3_21878914_ChIP-Seq_MCF-7_Human0.91185027
141OCT4_20526341_ChIP-Seq_ESCs_Human0.90976045

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis3.60092650
2MP0006276_abnormal_autonomic_nervous3.31416197
3MP0001188_hyperpigmentation3.29377268
4MP0006292_abnormal_olfactory_placode3.19271231
5MP0003315_abnormal_perineum_morphology2.92619573
6MP0002638_abnormal_pupillary_reflex2.86369478
7MP0005645_abnormal_hypothalamus_physiol2.68153630
8MP0002822_catalepsy2.67538642
9MP0009046_muscle_twitch2.67210337
10MP0005257_abnormal_intraocular_pressure2.64972488
11MP0002277_abnormal_respiratory_mucosa2.54997569
12MP0003195_calcinosis2.45032062
13MP0002735_abnormal_chemical_nociception2.34547052
14MP0008877_abnormal_DNA_methylation2.29237152
15MP0002653_abnormal_ependyma_morphology2.29095879
16MP0002102_abnormal_ear_morphology2.28933774
17MP0000778_abnormal_nervous_system2.22939470
18MP0001529_abnormal_vocalization2.21722446
19MP0002272_abnormal_nervous_system2.12345672
20MP0010386_abnormal_urinary_bladder2.07778501
21MP0005551_abnormal_eye_electrophysiolog2.05567395
22MP0004885_abnormal_endolymph2.01384874
23MP0001501_abnormal_sleep_pattern1.98013543
24MP0005646_abnormal_pituitary_gland1.88806175
25MP0008789_abnormal_olfactory_epithelium1.82135766
26MP0000049_abnormal_middle_ear1.79147589
27MP0005394_taste/olfaction_phenotype1.79037370
28MP0005499_abnormal_olfactory_system1.79037370
29MP0001486_abnormal_startle_reflex1.78917053
30MP0004043_abnormal_pH_regulation1.78682440
31MP0003385_abnormal_body_wall1.76907445
32MP0002160_abnormal_reproductive_system1.74415791
33MP0002184_abnormal_innervation1.73754683
34MP0003880_abnormal_central_pattern1.72656430
35MP0005423_abnormal_somatic_nervous1.72105476
36MP0003787_abnormal_imprinting1.70812380
37MP0004742_abnormal_vestibular_system1.67001046
38MP0008875_abnormal_xenobiotic_pharmacok1.66397216
39MP0002876_abnormal_thyroid_physiology1.58754438
40MP0002734_abnormal_mechanical_nocicepti1.55567900
41MP0002837_dystrophic_cardiac_calcinosis1.53316882
42MP0003941_abnormal_skin_development1.51448603
43MP0002163_abnormal_gland_morphology1.49741543
44MP0003938_abnormal_ear_development1.48785073
45MP0002736_abnormal_nociception_after1.47716438
46MP0002557_abnormal_social/conspecific_i1.47042105
47MP0001968_abnormal_touch/_nociception1.45384846
48MP0002751_abnormal_autonomic_nervous1.44561274
49MP0002909_abnormal_adrenal_gland1.44530635
50MP0005409_darkened_coat_color1.41735344
51MP0005379_endocrine/exocrine_gland_phen1.38749265
52MP0000569_abnormal_digit_pigmentation1.37920006
53MP0001485_abnormal_pinna_reflex1.36429465
54MP0009379_abnormal_foot_pigmentation1.36073853
55MP0000026_abnormal_inner_ear1.35755294
56MP0000372_irregular_coat_pigmentation1.35662126
57MP0001986_abnormal_taste_sensitivity1.32735813
58MP0000631_abnormal_neuroendocrine_gland1.32601824
59MP0000015_abnormal_ear_pigmentation1.32287692
60MP0004147_increased_porphyrin_level1.30965601
61MP0009250_abnormal_appendicular_skeleto1.29345704
62MP0006072_abnormal_retinal_apoptosis1.28444596
63MP0001970_abnormal_pain_threshold1.26554046
64MP0002234_abnormal_pharynx_morphology1.26401331
65MP0005075_abnormal_melanosome_morpholog1.25986415
66MP0002572_abnormal_emotion/affect_behav1.25915049
67MP0009697_abnormal_copulation1.25520228
68MP0008995_early_reproductive_senescence1.24887999
69MP0000427_abnormal_hair_cycle1.23700770
70MP0004142_abnormal_muscle_tone1.23606728
71MP0008872_abnormal_physiological_respon1.23115872
72MP0001963_abnormal_hearing_physiology1.22691525
73MP0003890_abnormal_embryonic-extraembry1.22101306
74MP0003646_muscle_fatigue1.21549535
75MP0009745_abnormal_behavioral_response1.21450641
76MP0000538_abnormal_urinary_bladder1.21127681
77MP0003122_maternal_imprinting1.20766425
78MP0002733_abnormal_thermal_nociception1.19517879
79MP0003011_delayed_dark_adaptation1.18880650
80MP0003121_genomic_imprinting1.18773045
81MP0002177_abnormal_outer_ear1.18413244
82MP0002063_abnormal_learning/memory/cond1.18038233
83MP0002233_abnormal_nose_morphology1.16031201
84MP0003937_abnormal_limbs/digits/tail_de1.14010970
85MP0001984_abnormal_olfaction1.11043073
86MP0001440_abnormal_grooming_behavior1.10846510
87MP0001502_abnormal_circadian_rhythm1.09474412
88MP0002229_neurodegeneration1.09024678
89MP0000462_abnormal_digestive_system1.08704421
90MP0001905_abnormal_dopamine_level1.08081727
91MP0002752_abnormal_somatic_nervous1.06594815
92MP0004859_abnormal_synaptic_plasticity1.06422308
93MP0003635_abnormal_synaptic_transmissio1.05249934
94MP0008004_abnormal_stomach_pH1.04576541
95MP0003119_abnormal_digestive_system1.02392767
96MP0002249_abnormal_larynx_morphology1.01992993
97MP0003755_abnormal_palate_morphology1.01988722
98MP0001177_atelectasis1.01645067
99MP0005187_abnormal_penis_morphology1.01023321
100MP0000678_abnormal_parathyroid_gland1.00070249
101MP0002067_abnormal_sensory_capabilities1.00010558
102MP0005389_reproductive_system_phenotype0.97391114
103MP0005195_abnormal_posterior_eye0.96648821
104MP0002066_abnormal_motor_capabilities/c0.94768193
105MP0002116_abnormal_craniofacial_bone0.94172295
106MP0004270_analgesia0.94060334
107MP0001346_abnormal_lacrimal_gland0.92594309
108MP0005253_abnormal_eye_physiology0.92401935
109MP0004133_heterotaxia0.92394120
110MP0003283_abnormal_digestive_organ0.91118784
111MP0002882_abnormal_neuron_morphology0.89778669
112MP0008058_abnormal_DNA_repair0.88773877
113MP0000613_abnormal_salivary_gland0.88491388
114MP0003698_abnormal_male_reproductive0.88480557
115MP0003861_abnormal_nervous_system0.88472573
116MP0003633_abnormal_nervous_system0.86250402
117MP0002064_seizures0.86159269
118MP0004858_abnormal_nervous_system0.85843946
119MP0002938_white_spotting0.85759853
120MP0002928_abnormal_bile_duct0.84673590
121MP0002069_abnormal_eating/drinking_beha0.84417322
122MP0005171_absent_coat_pigmentation0.83760606
123MP0004924_abnormal_behavior0.83725388
124MP0005386_behavior/neurological_phenoty0.83725388
125MP0005174_abnormal_tail_pigmentation0.82964750
126MP0005410_abnormal_fertilization0.82660080
127MP0001286_abnormal_eye_development0.81178513
128MP0001919_abnormal_reproductive_system0.80235545
129MP0004782_abnormal_surfactant_physiolog0.79649397
130MP0003878_abnormal_ear_physiology0.79232542
131MP0005377_hearing/vestibular/ear_phenot0.79232542
132MP0005167_abnormal_blood-brain_barrier0.79088744
133MP0000955_abnormal_spinal_cord0.77096292
134MP0003136_yellow_coat_color0.76453079
135MP0003631_nervous_system_phenotype0.75087824
136MP0004145_abnormal_muscle_electrophysio0.74745644
137MP0002152_abnormal_brain_morphology0.73072271
138MP0004811_abnormal_neuron_physiology0.70292207
139MP0001727_abnormal_embryo_implantation0.69337912

Predicted human phenotypes

RankGene SetZ-score
1Type II lissencephaly (HP:0007260)3.63051218
2Chromosomal breakage induced by crosslinking agents (HP:0003221)3.53317600
3Nephronophthisis (HP:0000090)3.51983165
4Focal seizures (HP:0007359)3.34865711
5Congenital stationary night blindness (HP:0007642)3.26393230
6Progressive cerebellar ataxia (HP:0002073)3.14527358
7Genetic anticipation (HP:0003743)2.97895674
8Hypothermia (HP:0002045)2.93358932
9Absent/shortened dynein arms (HP:0200106)2.84001507
10Dynein arm defect of respiratory motile cilia (HP:0012255)2.84001507
11Anomalous pulmonary venous return (HP:0010772)2.84001493
12Dialeptic seizures (HP:0011146)2.82145093
13Absent speech (HP:0001344)2.81707082
14Bifid tongue (HP:0010297)2.78358259
15Inability to walk (HP:0002540)2.78012841
16Septo-optic dysplasia (HP:0100842)2.77839196
17Abnormality of the intervertebral disk (HP:0005108)2.77184840
18Chromsome breakage (HP:0040012)2.74406633
19Protruding tongue (HP:0010808)2.73333499
20Gaze-evoked nystagmus (HP:0000640)2.72816050
21Cystic liver disease (HP:0006706)2.71962096
22Drooling (HP:0002307)2.69200980
23Retinal dysplasia (HP:0007973)2.68764785
24Morphological abnormality of the middle ear (HP:0008609)2.65806501
25Abnormality of the renal collecting system (HP:0004742)2.65391232
26Severe muscular hypotonia (HP:0006829)2.63110958
27Attenuation of retinal blood vessels (HP:0007843)2.61305794
28Septate vagina (HP:0001153)2.58904464
29Medial flaring of the eyebrow (HP:0010747)2.58361684
30Pancreatic cysts (HP:0001737)2.57712440
31Gait imbalance (HP:0002141)2.57004090
32Nephrogenic diabetes insipidus (HP:0009806)2.56424871
33Epileptic encephalopathy (HP:0200134)2.53283679
34Pancreatic fibrosis (HP:0100732)2.50311024
35Abnormal hair whorl (HP:0010721)2.50193639
36Stomach cancer (HP:0012126)2.49330722
37Chronic hepatic failure (HP:0100626)2.47773556
38Abnormal respiratory motile cilium morphology (HP:0005938)2.46123737
39Abnormal respiratory epithelium morphology (HP:0012253)2.46123737
40Pachygyria (HP:0001302)2.44824005
41Excessive salivation (HP:0003781)2.43224204
42Absent rod-and cone-mediated responses on ERG (HP:0007688)2.41682559
43Febrile seizures (HP:0002373)2.41113241
44Abnormality of the pulmonary veins (HP:0011718)2.39416371
45Limb dystonia (HP:0002451)2.38242211
46Absence seizures (HP:0002121)2.36234191
47True hermaphroditism (HP:0010459)2.34582886
48Alveolar cell carcinoma (HP:0006519)2.33860959
49Midline defect of the nose (HP:0004122)2.33432833
50Abnormal drinking behavior (HP:0030082)2.32787951
51Polydipsia (HP:0001959)2.32787951
523-Methylglutaconic aciduria (HP:0003535)2.30165094
53Abnormality of the lacrimal duct (HP:0011481)2.29574096
54Progressive inability to walk (HP:0002505)2.27242153
55Clumsiness (HP:0002312)2.26356546
56Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.26165149
57Increased number of teeth (HP:0011069)2.26146304
58Atonic seizures (HP:0010819)2.25783865
59Congenital primary aphakia (HP:0007707)2.25481273
60Congenital sensorineural hearing impairment (HP:0008527)2.25350540
61Agitation (HP:0000713)2.25133451
62Gastroesophageal reflux (HP:0002020)2.23656368
63Decreased circulating renin level (HP:0003351)2.22880761
64Abnormality of the nasolacrimal system (HP:0000614)2.21801337
65Sclerocornea (HP:0000647)2.20786071
66Abolished electroretinogram (ERG) (HP:0000550)2.19299479
67Focal motor seizures (HP:0011153)2.17296206
68Pendular nystagmus (HP:0012043)2.16836285
69Myokymia (HP:0002411)2.16460228
70Decreased central vision (HP:0007663)2.16277103
71Bony spicule pigmentary retinopathy (HP:0007737)2.16147491
72Large for gestational age (HP:0001520)2.15814716
73Absent eyebrow (HP:0002223)2.12491712
74Hemiparesis (HP:0001269)2.12453850
75Increased hepatocellular lipid droplets (HP:0006565)2.12268027
76Microglossia (HP:0000171)2.12081648
77Furrowed tongue (HP:0000221)2.12080295
78Patellar aplasia (HP:0006443)2.10606609
79Aplasia cutis congenita (HP:0001057)2.10448557
80Intellectual disability, moderate (HP:0002342)2.07094196
81Ketosis (HP:0001946)2.06932338
82Anencephaly (HP:0002323)2.06194642
83Polymicrogyria (HP:0002126)2.05893418
84Poor suck (HP:0002033)2.05291642
85Abnormal ciliary motility (HP:0012262)2.04570445
86Vaginal atresia (HP:0000148)2.04423904
87Genital tract atresia (HP:0001827)2.04416127
88Abnormality of the septum pellucidum (HP:0007375)2.04335075
89Hypoplasia of the brainstem (HP:0002365)2.03764272
90Aplasia/Hypoplasia of the brainstem (HP:0007362)2.03764272
91Cerebellar dysplasia (HP:0007033)2.02641837
92Hypoplastic iliac wings (HP:0002866)2.02182941
93Exotropia (HP:0000577)2.02030961
94Nasolacrimal duct obstruction (HP:0000579)2.02011807
95Hypsarrhythmia (HP:0002521)2.01896034
96Abnormality of the pons (HP:0007361)2.01737634
97Aplasia/Hypoplasia of the patella (HP:0006498)2.01309274
98Abnormality of alanine metabolism (HP:0010916)2.00903314
99Hyperalaninemia (HP:0003348)2.00903314
100Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.00903314
101Abnormality of the preputium (HP:0100587)2.00861510
102Renal hypoplasia (HP:0000089)2.00294404
103Tongue fasciculations (HP:0001308)2.00271075
104Bile duct proliferation (HP:0001408)2.00074860
105Abnormal biliary tract physiology (HP:0012439)2.00074860
106Hypoplasia of the pons (HP:0012110)1.96905548
107Atelectasis (HP:0100750)1.96811129
108Lissencephaly (HP:0001339)1.96730373
109EEG with generalized epileptiform discharges (HP:0011198)1.95932993
110Epileptiform EEG discharges (HP:0011182)1.94485410
111Optic nerve hypoplasia (HP:0000609)1.94482312
112Large eyes (HP:0001090)1.93693566
113Abnormal lung lobation (HP:0002101)1.93624107
114Submucous cleft hard palate (HP:0000176)1.92835984
115Abnormal rod and cone electroretinograms (HP:0008323)1.92832787
116Ectopic kidney (HP:0000086)1.92605807
117Male pseudohermaphroditism (HP:0000037)1.92231469
118Duplicated collecting system (HP:0000081)1.91809041
119Aplasia/Hypoplasia of the uvula (HP:0010293)1.91185227
120Specific learning disability (HP:0001328)1.90529602
121Neoplasm of the tracheobronchial system (HP:0100552)1.88651639
122Aplasia/Hypoplasia of the tibia (HP:0005772)1.88478254
123Occipital encephalocele (HP:0002085)1.88475501
124Hepatoblastoma (HP:0002884)1.86871270
125Renal cortical cysts (HP:0000803)1.86735504
126Meckel diverticulum (HP:0002245)1.85504744
127Generalized tonic-clonic seizures (HP:0002069)1.84117520
128Renal dysplasia (HP:0000110)1.83544039
129Renal Fanconi syndrome (HP:0001994)1.83427396
130Capillary hemangiomas (HP:0005306)1.82622259
131Narrow forehead (HP:0000341)1.82590307
132Astigmatism (HP:0000483)1.82255158
133Facial cleft (HP:0002006)1.82248047
134Congenital hepatic fibrosis (HP:0002612)1.81091652
135Abnormality of the renal medulla (HP:0100957)1.81035228
136Aplasia/hypoplasia of the uterus (HP:0008684)1.80961531
137Poor coordination (HP:0002370)1.80564540
138Tubular atrophy (HP:0000092)1.80202636
139Ketoacidosis (HP:0001993)1.79845284
140Optic disc pallor (HP:0000543)1.78103651
141Tachypnea (HP:0002789)1.77852938
142Cupped ear (HP:0000378)1.77685580
143Abnormality of incisor morphology (HP:0011063)1.77516758
144Impulsivity (HP:0100710)1.76900968
145Aplasia/Hypoplasia of the lens (HP:0008063)1.76893935
146Polyuria (HP:0000103)1.76561412
147Short tibia (HP:0005736)1.76542409
148Renal agenesis (HP:0000104)1.75816706
149Barrel-shaped chest (HP:0001552)1.75440007
150Self-mutilation (HP:0000742)1.75112858
151Abnormality of the ileum (HP:0001549)1.73687232
152Aganglionic megacolon (HP:0002251)1.73494676
153Facial hemangioma (HP:0000329)1.72555110
154Progressive macrocephaly (HP:0004481)1.71392148
155Sleep apnea (HP:0010535)1.70717185
156Aplasia/Hypoplasia of the tongue (HP:0010295)1.70098230
157Abnormality of the renal cortex (HP:0011035)1.69751183
158Hyperventilation (HP:0002883)1.69567396
159Preaxial hand polydactyly (HP:0001177)1.68725554
160Stenosis of the external auditory canal (HP:0000402)1.67288647
161Fair hair (HP:0002286)1.65752030
162Abnormality of midbrain morphology (HP:0002418)1.65724278
163Molar tooth sign on MRI (HP:0002419)1.65724278
164Polyphagia (HP:0002591)1.65706927
165Tubulointerstitial nephritis (HP:0001970)1.65345782
166Postaxial foot polydactyly (HP:0001830)1.64027085
167Broad-based gait (HP:0002136)1.62932458
168Abnormality of the labia minora (HP:0012880)1.62515203
169Acute necrotizing encephalopathy (HP:0006965)1.62204401

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.20083185
2CASK4.13751545
3ACVR1B3.74674607
4MAP4K23.17667363
5SIK33.17323885
6MARK13.09897039
7CDK82.88364540
8BMPR1B2.65515795
9AKT32.64789019
10DYRK22.46911451
11MAPK132.13827789
12NUAK12.10036388
13DAPK22.01088632
14EPHB21.99867259
15MAP2K71.98950921
16PINK11.96966619
17PLK41.96657479
18SRPK11.95704888
19ZAK1.88399001
20YES11.81616925
21INSRR1.70928476
22TBK11.68757066
23TNIK1.67554697
24BCR1.65705026
25NTRK21.65145233
26NEK61.63907920
27EIF2AK21.61819717
28TAOK31.60309306
29MKNK21.59922212
30SGK21.55771933
31PAK31.49874754
32PKN11.45291906
33EPHA41.45085255
34WNK41.42262662
35TLK11.42079042
36SGK4941.40585511
37SGK2231.40585511
38PLK21.40498865
39OXSR11.39676115
40ERBB31.35602140
41ADRBK21.34438389
42GRK71.32347640
43IKBKE1.30384543
44PRKCG1.26644830
45STK161.19701001
46MAP2K41.18872796
47IRAK31.18816734
48TXK1.18001352
49ERBB41.13203994
50MKNK11.08388018
51BRAF1.06650394
52TRIM281.06645997
53CSNK1G21.04532331
54MST41.01507482
55IRAK21.01065536
56NTRK31.00639640
57VRK10.99667445
58CDK190.98620550
59UHMK10.92716431
60IRAK40.90519708
61CSNK1G30.89819818
62STK38L0.89698076
63PIK3CG0.87199255
64PIK3CA0.85403952
65CSNK1A1L0.85069490
66PRPF4B0.84934348
67CAMKK20.83836354
68WNK30.80981453
69MINK10.80564311
70CAMK1D0.79791407
71CSNK1G10.77497770
72PRKCE0.75844632
73PRKCZ0.75106993
74PAK60.74697336
75EIF2AK10.74461094
76FGFR20.73789620
77LATS20.72767799
78CDK30.70703593
79IRAK10.70050537
80DYRK1A0.69840455
81STK110.69267724
82MAP3K40.68372244
83CHEK20.68158387
84CAMK1G0.67733637
85MUSK0.66398005
86BCKDK0.65325203
87FER0.62279581
88PNCK0.61410567
89EPHA30.61035088
90PLK30.59874601
91PRKCI0.58809494
92SGK30.58554013
93PRKAA10.57850579
94CAMK10.57455542
95MAP3K140.55577052
96NLK0.55175471
97MAP2K60.55137111
98RPS6KA20.55033334
99IKBKB0.54617806
100GRK10.54606457
101MARK20.51285011
102ADRBK10.50129794
103STK390.49975634
104TYRO30.49936134
105MAPKAPK30.48427220
106TEC0.48046828
107PRKACA0.47580676
108DMPK0.47163108
109PRKCH0.46841858
110PTK2B0.45571990
111MAP3K110.44395124
112CDK50.44393448
113CSNK1D0.43961561
114CSNK1A10.43861884
115MAPK150.43471819
116DYRK30.43379857
117SIK20.43075340
118CDK70.41495811
119TGFBR10.40492110
120BMPR20.39911545
121CAMKK10.38587051
122TNK20.38554837
123PLK10.37625070
124SGK10.35201018
125GRK50.34729737
126TAOK20.33932576
127PRKCA0.32810987
128MAPKAPK50.32612189
129ERBB20.31926515
130CAMK2A0.31306180
131PRKG10.31305396
132MAP2K20.31046225
133HIPK20.30467117
134TIE10.30101114
135PIM20.30046102
136AKT20.30044786
137PRKACB0.29752712
138ATR0.29746145
139CCNB10.29052321
140MAP3K120.28747252
141MAPK140.28253436
142GSK3B0.28200249
143CAMK40.28165137
144NME10.28058529
145IGF1R0.27849759
146ITK0.27426059
147RPS6KA50.27236920
148BRD40.27021603
149CDK10.27001143
150PHKG10.26032695
151PHKG20.26032695

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.82142124
2Steroid biosynthesis_Homo sapiens_hsa001002.73509703
3Butanoate metabolism_Homo sapiens_hsa006502.55721067
4Linoleic acid metabolism_Homo sapiens_hsa005912.45693644
5Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.40646506
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.29533804
7Fanconi anemia pathway_Homo sapiens_hsa034602.18448931
8Tryptophan metabolism_Homo sapiens_hsa003801.91076947
9Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.90991778
10RNA polymerase_Homo sapiens_hsa030201.90386660
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.90016634
12Axon guidance_Homo sapiens_hsa043601.89017820
13Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.84768165
14Basal transcription factors_Homo sapiens_hsa030221.75865304
15Taste transduction_Homo sapiens_hsa047421.73343367
16Nitrogen metabolism_Homo sapiens_hsa009101.72570157
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.67601694
18Selenocompound metabolism_Homo sapiens_hsa004501.61649370
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.59349428
20Serotonergic synapse_Homo sapiens_hsa047261.58146818
21Autoimmune thyroid disease_Homo sapiens_hsa053201.53515937
22Basal cell carcinoma_Homo sapiens_hsa052171.52361657
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.45614519
24Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.45605665
25Caffeine metabolism_Homo sapiens_hsa002321.44453696
26Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.42466987
27Morphine addiction_Homo sapiens_hsa050321.36082425
28Oxidative phosphorylation_Homo sapiens_hsa001901.32088823
29Primary bile acid biosynthesis_Homo sapiens_hsa001201.31784510
30Phototransduction_Homo sapiens_hsa047441.30257471
31Spliceosome_Homo sapiens_hsa030401.27929677
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.26576949
33ABC transporters_Homo sapiens_hsa020101.25013059
34Melanoma_Homo sapiens_hsa052181.16838973
35Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.15212524
36Type I diabetes mellitus_Homo sapiens_hsa049401.12380917
37Wnt signaling pathway_Homo sapiens_hsa043101.12311605
38Cocaine addiction_Homo sapiens_hsa050301.11944981
39Salivary secretion_Homo sapiens_hsa049701.10688610
40Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.08824884
41Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.07373426
42Ovarian steroidogenesis_Homo sapiens_hsa049131.07341456
43Chemical carcinogenesis_Homo sapiens_hsa052041.06435568
44Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.05912371
45Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.04648058
46Allograft rejection_Homo sapiens_hsa053301.04068929
47Cholinergic synapse_Homo sapiens_hsa047251.03816550
48Intestinal immune network for IgA production_Homo sapiens_hsa046721.02833499
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.01879364
50Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.00640708
51Long-term depression_Homo sapiens_hsa047300.99959491
52Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.99775313
53Graft-versus-host disease_Homo sapiens_hsa053320.99578105
54Olfactory transduction_Homo sapiens_hsa047400.97929902
55Cardiac muscle contraction_Homo sapiens_hsa042600.97788075
56RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.96851137
57Hedgehog signaling pathway_Homo sapiens_hsa043400.96373941
58Homologous recombination_Homo sapiens_hsa034400.96268648
59Toll-like receptor signaling pathway_Homo sapiens_hsa046200.95451761
60ErbB signaling pathway_Homo sapiens_hsa040120.95081491
61Propanoate metabolism_Homo sapiens_hsa006400.94759738
62Huntingtons disease_Homo sapiens_hsa050160.93821562
63Retinol metabolism_Homo sapiens_hsa008300.92418751
64Rheumatoid arthritis_Homo sapiens_hsa053230.91035781
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90993566
66Sphingolipid metabolism_Homo sapiens_hsa006000.89139037
67Glutamatergic synapse_Homo sapiens_hsa047240.87939075
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.87070743
69Notch signaling pathway_Homo sapiens_hsa043300.86717812
70Parkinsons disease_Homo sapiens_hsa050120.86590908
71Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.86142898
72GABAergic synapse_Homo sapiens_hsa047270.85275591
73beta-Alanine metabolism_Homo sapiens_hsa004100.84672646
74Peroxisome_Homo sapiens_hsa041460.84575990
75Gastric acid secretion_Homo sapiens_hsa049710.84248319
76Measles_Homo sapiens_hsa051620.81837635
77Rap1 signaling pathway_Homo sapiens_hsa040150.81281292
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81029717
79Circadian entrainment_Homo sapiens_hsa047130.80433123
80Mineral absorption_Homo sapiens_hsa049780.80097485
81Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79196822
82Purine metabolism_Homo sapiens_hsa002300.78812342
83cAMP signaling pathway_Homo sapiens_hsa040240.78019371
84Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.77761027
85Type II diabetes mellitus_Homo sapiens_hsa049300.77527734
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76212900
87Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.76082845
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.76017202
89Influenza A_Homo sapiens_hsa051640.75327058
90Aldosterone synthesis and secretion_Homo sapiens_hsa049250.75266611
91Protein export_Homo sapiens_hsa030600.75174300
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.75114515
93Pyrimidine metabolism_Homo sapiens_hsa002400.75090875
94Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.73533037
95Histidine metabolism_Homo sapiens_hsa003400.73063735
96Ras signaling pathway_Homo sapiens_hsa040140.71426283
97Oxytocin signaling pathway_Homo sapiens_hsa049210.70720582
98Choline metabolism in cancer_Homo sapiens_hsa052310.69696416
99Melanogenesis_Homo sapiens_hsa049160.69662498
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.69526020
101Alcoholism_Homo sapiens_hsa050340.69515722
102Hepatitis C_Homo sapiens_hsa051600.69295149
103Endometrial cancer_Homo sapiens_hsa052130.68212336
104NF-kappa B signaling pathway_Homo sapiens_hsa040640.68129790
105Alzheimers disease_Homo sapiens_hsa050100.67517473
106Colorectal cancer_Homo sapiens_hsa052100.67267917
107Insulin secretion_Homo sapiens_hsa049110.66958333
108RNA degradation_Homo sapiens_hsa030180.66274540
109Hippo signaling pathway_Homo sapiens_hsa043900.64965154
110Asthma_Homo sapiens_hsa053100.64772005
111Pertussis_Homo sapiens_hsa051330.64299480
112Phagosome_Homo sapiens_hsa041450.64288573
113Herpes simplex infection_Homo sapiens_hsa051680.63545178
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62944238
115Synaptic vesicle cycle_Homo sapiens_hsa047210.62468849
116Regulation of autophagy_Homo sapiens_hsa041400.62168213
117Glycerolipid metabolism_Homo sapiens_hsa005610.61003712
118Collecting duct acid secretion_Homo sapiens_hsa049660.60958700
119Renin secretion_Homo sapiens_hsa049240.59622389
120Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58796207
121Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.57970952
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57912390
123Arachidonic acid metabolism_Homo sapiens_hsa005900.57316907
124Sulfur relay system_Homo sapiens_hsa041220.55598943
125Fatty acid metabolism_Homo sapiens_hsa012120.55177534
126Hematopoietic cell lineage_Homo sapiens_hsa046400.53134163
127Calcium signaling pathway_Homo sapiens_hsa040200.52994106
128Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.52930411
129Dopaminergic synapse_Homo sapiens_hsa047280.52917897
130Pancreatic cancer_Homo sapiens_hsa052120.52860538
131Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.52622596
132Base excision repair_Homo sapiens_hsa034100.52211585
133Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50205837
134Steroid hormone biosynthesis_Homo sapiens_hsa001400.48992619
135Vascular smooth muscle contraction_Homo sapiens_hsa042700.48073228
136Ether lipid metabolism_Homo sapiens_hsa005650.47468121
137Circadian rhythm_Homo sapiens_hsa047100.47363325
138Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46163544
139mRNA surveillance pathway_Homo sapiens_hsa030150.45666293
140TNF signaling pathway_Homo sapiens_hsa046680.45494269
141Metabolic pathways_Homo sapiens_hsa011000.45059763
142Bile secretion_Homo sapiens_hsa049760.44460579
143Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43710291
144Amphetamine addiction_Homo sapiens_hsa050310.43059004
145Dorso-ventral axis formation_Homo sapiens_hsa043200.42714962
146Pathways in cancer_Homo sapiens_hsa052000.42501039
147NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41827726
148Systemic lupus erythematosus_Homo sapiens_hsa053220.41307396
149Fat digestion and absorption_Homo sapiens_hsa049750.39897927
150Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39491819
151Fatty acid biosynthesis_Homo sapiens_hsa000610.38436646
152African trypanosomiasis_Homo sapiens_hsa051430.38113049
153Cysteine and methionine metabolism_Homo sapiens_hsa002700.34072579
154Fatty acid elongation_Homo sapiens_hsa000620.29442550

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