GFPT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1keratan sulfate catabolic process (GO:0042340)6.59826437
2collagen fibril organization (GO:0030199)5.89427772
3cartilage development involved in endochondral bone morphogenesis (GO:0060351)5.76246801
4notochord development (GO:0030903)5.75038679
5cartilage condensation (GO:0001502)5.58092188
6cell aggregation (GO:0098743)5.58092188
7establishment of integrated proviral latency (GO:0075713)5.39367369
8chondrocyte development (GO:0002063)5.14325476
9extracellular fibril organization (GO:0043206)4.86719150
10establishment of viral latency (GO:0019043)4.75452997
11protein heterotrimerization (GO:0070208)4.70654733
12regulation of posttranscriptional gene silencing (GO:0060147)4.54408295
13regulation of gene silencing by miRNA (GO:0060964)4.54408295
14regulation of gene silencing by RNA (GO:0060966)4.54408295
15paraxial mesoderm development (GO:0048339)4.40807839
16protein complex localization (GO:0031503)4.35985379
17L-serine metabolic process (GO:0006563)4.35934926
18endothelial cell morphogenesis (GO:0001886)4.30501252
19nuclear pore organization (GO:0006999)4.29959644
20fibril organization (GO:0097435)4.26937803
21nuclear pore complex assembly (GO:0051292)4.19795569
22cellular protein complex localization (GO:0034629)4.03338346
23heterochromatin organization (GO:0070828)3.90518026
24positive regulation of SMAD protein import into nucleus (GO:0060391)3.87876584
25chondrocyte proliferation (GO:0035988)3.80432919
26regulation of cell fate specification (GO:0042659)3.79581200
27regulation of SMAD protein import into nucleus (GO:0060390)3.74845300
28bone trabecula formation (GO:0060346)3.74786690
29collagen metabolic process (GO:0032963)3.63957922
30collagen catabolic process (GO:0030574)3.58715038
31sequestering of extracellular ligand from receptor (GO:0035581)3.57119666
32cell migration involved in sprouting angiogenesis (GO:0002042)3.52922845
33negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.52499157
34regulation of transforming growth factor beta2 production (GO:0032909)3.43097623
35multicellular organismal macromolecule metabolic process (GO:0044259)3.39545342
36dermatan sulfate biosynthetic process (GO:0030208)3.36578124
37pre-miRNA processing (GO:0031054)3.32571506
38mitotic metaphase plate congression (GO:0007080)3.30297369
39multicellular organismal catabolic process (GO:0044243)3.27119173
40pore complex assembly (GO:0046931)3.24378917
41multicellular organismal metabolic process (GO:0044236)3.23478689
42anterior/posterior axis specification, embryo (GO:0008595)3.23140361
43ventricular cardiac muscle cell development (GO:0055015)3.22836467
44metanephric mesenchyme development (GO:0072075)3.20473229
45protein localization to kinetochore (GO:0034501)3.20120781
46planar cell polarity pathway involved in neural tube closure (GO:0090179)3.18587724
47peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.17561777
48pericardium development (GO:0060039)3.16246884
49negative regulation of chondrocyte differentiation (GO:0032331)3.14866357
50neuron projection extension involved in neuron projection guidance (GO:1902284)3.14242434
51axon extension involved in axon guidance (GO:0048846)3.14242434
52regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.13219812
53kidney mesenchyme development (GO:0072074)3.12990696
54positive regulation of endothelial cell differentiation (GO:0045603)3.12410767
55negative regulation of androgen receptor signaling pathway (GO:0060766)3.11023638
56endocardial cushion morphogenesis (GO:0003203)3.09641911
57cranial suture morphogenesis (GO:0060363)3.08038015
58glomerular visceral epithelial cell development (GO:0072015)3.07537896
59limb bud formation (GO:0060174)3.04530713
60IMP biosynthetic process (GO:0006188)3.04364551
61retina vasculature morphogenesis in camera-type eye (GO:0061299)3.04268626
62branching involved in salivary gland morphogenesis (GO:0060445)3.01336891
63extracellular matrix assembly (GO:0085029)3.01250679
64response to BMP (GO:0071772)3.00849997
65cellular response to BMP stimulus (GO:0071773)3.00849997
66nucleobase biosynthetic process (GO:0046112)3.00768584
67extracellular matrix disassembly (GO:0022617)2.98539301
68protein maturation by protein folding (GO:0022417)2.96908619
69dermatan sulfate metabolic process (GO:0030205)2.95662860
70negative regulation of cartilage development (GO:0061037)2.95285262
71negative regulation of telomerase activity (GO:0051974)2.94408096
72craniofacial suture morphogenesis (GO:0097094)2.94086578
73folic acid-containing compound biosynthetic process (GO:0009396)2.93866268
74chondroitin sulfate biosynthetic process (GO:0030206)2.93501185
75DNA unwinding involved in DNA replication (GO:0006268)2.92539008
76ribosome assembly (GO:0042255)2.91873466
77keratan sulfate biosynthetic process (GO:0018146)2.91261181
78regulation of mesoderm development (GO:2000380)2.89316846
79convergent extension (GO:0060026)2.88656470
80basement membrane organization (GO:0071711)2.88127166
81regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.87012517
82cell adhesion mediated by integrin (GO:0033627)2.86516743
83metaphase plate congression (GO:0051310)2.85007791
84mesenchyme morphogenesis (GO:0072132)2.83969778
85cell fate commitment involved in formation of primary germ layer (GO:0060795)2.81889035
86mesenchymal-epithelial cell signaling (GO:0060638)2.80675814
87atrioventricular valve morphogenesis (GO:0003181)2.78821246
88embryonic skeletal joint morphogenesis (GO:0060272)2.78615417
89negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)2.78330227
90maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.78214025
91endodermal cell differentiation (GO:0035987)2.77880749
92positive regulation of catenin import into nucleus (GO:0035413)2.77740227
93regulation of mitotic spindle organization (GO:0060236)2.77279163
94regulation of gastrulation (GO:0010470)2.76536820
95negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.76315585
96negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.76315585
97negative regulation of mitotic sister chromatid segregation (GO:0033048)2.76315585
98negative regulation of mitotic sister chromatid separation (GO:2000816)2.76315585
99negative regulation of sister chromatid segregation (GO:0033046)2.76315585
100branching involved in labyrinthine layer morphogenesis (GO:0060670)2.74229069
101substrate-dependent cell migration (GO:0006929)2.73463129
102mitotic nuclear envelope disassembly (GO:0007077)2.73355653
103protein retention in ER lumen (GO:0006621)2.71975045
104hippo signaling (GO:0035329)2.71012459
105lung-associated mesenchyme development (GO:0060484)2.70817869
106negative regulation of chromosome segregation (GO:0051985)2.70014792
107replacement ossification (GO:0036075)2.68956667
108endochondral ossification (GO:0001958)2.68956667
109extracellular structure organization (GO:0043062)2.68873360
110cellular response to hepatocyte growth factor stimulus (GO:0035729)2.68551922
111response to hepatocyte growth factor (GO:0035728)2.68551922
112extracellular matrix organization (GO:0030198)2.68268497
113cartilage development (GO:0051216)2.67918768
114histone arginine methylation (GO:0034969)2.67295211
115proteasome assembly (GO:0043248)2.66278673
116mammary gland development (GO:0030879)2.65978656
117nodal signaling pathway (GO:0038092)2.65290904
118skin morphogenesis (GO:0043589)2.63157138
119cardiac epithelial to mesenchymal transition (GO:0060317)2.63115424
120negative regulation of smooth muscle cell migration (GO:0014912)2.62374179
121regulation of hippo signaling (GO:0035330)2.62156587
122trophoblast giant cell differentiation (GO:0060707)2.59591637
123glomerular basement membrane development (GO:0032836)2.59170265
124regulation of cardiac muscle cell differentiation (GO:2000725)2.58981148
125purine nucleobase biosynthetic process (GO:0009113)2.58433491
126protein K6-linked ubiquitination (GO:0085020)2.57675621
127regulation of helicase activity (GO:0051095)2.57592809
128protein localization to cell surface (GO:0034394)2.57287540
129regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.56976471
130membrane disassembly (GO:0030397)2.56847228
131nuclear envelope disassembly (GO:0051081)2.56847228
132positive regulation of osteoblast proliferation (GO:0033690)2.56647485
133G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.55370541
134positive regulation of astrocyte differentiation (GO:0048711)2.54560032
135regulation of epithelial cell differentiation involved in kidney development (GO:2000696)2.54403508
136DNA replication-dependent nucleosome assembly (GO:0006335)2.54152400
137DNA replication-dependent nucleosome organization (GO:0034723)2.54152400
138somatic hypermutation of immunoglobulin genes (GO:0016446)2.53535308
139somatic diversification of immune receptors via somatic mutation (GO:0002566)2.53535308
140regulation of centriole replication (GO:0046599)2.51844135
141glomerular epithelial cell development (GO:0072310)2.51726583
142response to X-ray (GO:0010165)2.50868244
143mitotic spindle checkpoint (GO:0071174)2.50823090
144barbed-end actin filament capping (GO:0051016)2.50787380
145positive regulation of cartilage development (GO:0061036)2.50766429
146regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.50726235
147DNA replication initiation (GO:0006270)2.50413546
148female gonad development (GO:0008585)2.49143676
149spindle checkpoint (GO:0031577)2.48283508
150regulation of cell fate commitment (GO:0010453)2.47976865
151regulation of chondrocyte differentiation (GO:0032330)2.47834746
152muscle cell migration (GO:0014812)2.47758265
153IMP metabolic process (GO:0046040)2.47060123
154wound healing, spreading of epidermal cells (GO:0035313)2.45387312
155skeletal system development (GO:0001501)2.44636353
156regulation of catenin import into nucleus (GO:0035412)2.44421818
157regulation of spindle organization (GO:0090224)2.44017474
158epithelial cell-cell adhesion (GO:0090136)2.43520973
159negative regulation of intracellular steroid hormone receptor signaling pathway (GO:0033144)2.43447938
160somite development (GO:0061053)2.43429836
161* nucleotide-sugar biosynthetic process (GO:0009226)2.42896317
162negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.42801638
163regulation of endothelial cell differentiation (GO:0045601)2.42653741
164protein localization to chromosome, centromeric region (GO:0071459)2.42314405
165nuclear envelope reassembly (GO:0031468)2.41990876
166mitotic nuclear envelope reassembly (GO:0007084)2.41990876
167regulation of cartilage development (GO:0061035)2.41002589
168cell surface receptor signaling pathway involved in heart development (GO:0061311)2.40589595
169mitotic spindle assembly checkpoint (GO:0007094)2.40565176
170positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.40407277
171regulation of telomere maintenance via telomerase (GO:0032210)2.40394644
172negative regulation of cell fate specification (GO:0009996)2.40384418
173positive regulation of chondrocyte differentiation (GO:0032332)2.40358835

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.03460694
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.91103144
3KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.57552009
4KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.57552009
5KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.57552009
6* MYC_18555785_ChIP-Seq_MESCs_Mouse3.30882907
7SALL1_21062744_ChIP-ChIP_HESCs_Human3.27008334
8NANOG_18700969_ChIP-ChIP_MESCs_Mouse3.20524871
9TP63_17297297_ChIP-ChIP_HaCaT_Human3.08236982
10POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.88673829
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.77998820
12TCF3_18692474_ChIP-Seq_MEFs_Mouse2.75503568
13SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.71325025
14NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.70669914
15ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.58432301
16HIF1A_21447827_ChIP-Seq_MCF-7_Human2.52684008
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.50026719
18* SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.48632400
19SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.40187110
20SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.35877787
21* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.30237602
22ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.18337801
23TCF3_18692474_ChIP-Seq_MESCs_Mouse2.17172920
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.09822415
25* STAT3_1855785_ChIP-Seq_MESCs_Mouse2.08025359
26POU5F1_18358816_ChIP-ChIP_MESCs_Mouse2.06124991
27SOX2_18555785_ChIP-Seq_MESCs_Mouse2.04694611
28MYC_19030024_ChIP-ChIP_MESCs_Mouse2.00949732
29NANOG_18555785_ChIP-Seq_MESCs_Mouse2.00547393
30RARG_19884340_ChIP-ChIP_MEFs_Mouse2.00130276
31ESR1_21235772_ChIP-Seq_MCF-7_Human1.98311851
32* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.97277832
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.95615087
34TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.90475006
35HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.87626437
36RBPJ_22232070_ChIP-Seq_NCS_Mouse1.86520522
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.82462866
38PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.78733088
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.72615804
40WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.70656088
41FOXM1_23109430_ChIP-Seq_U2OS_Human1.65527414
42DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.64758546
43SMAD_19615063_ChIP-ChIP_OVARY_Human1.61492301
44RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.60070147
45SOX2_16153702_ChIP-ChIP_HESCs_Human1.59641932
46* BRD4_25478319_ChIP-Seq_HGPS_Human1.58213300
47KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.57914458
48* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.55202104
49NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.54407926
50CJUN_26792858_Chip-Seq_BT549_Human1.50256198
51SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.50198361
52AR_21572438_ChIP-Seq_LNCaP_Human1.50050653
53* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.44216480
54NANOG_18692474_ChIP-Seq_MEFs_Mouse1.43611339
55CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.42243576
56AR_21909140_ChIP-Seq_LNCAP_Human1.42122595
57TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.41383797
58CLOCK_20551151_ChIP-Seq_293T_Human1.40703987
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.39475822
60SALL4_18804426_ChIP-ChIP_XEN_Mouse1.38249143
61* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.35750884
62HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.35160382
63TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.34781109
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.34703815
65CREB1_15753290_ChIP-ChIP_HEK293T_Human1.33913265
66KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.32114548
67WT1_19549856_ChIP-ChIP_CCG9911_Human1.31875903
68NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.31603057
69CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.30727752
70NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.30721112
71NANOG_16153702_ChIP-ChIP_HESCs_Human1.30322760
72POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.29051275
73* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.28700982
74MYC_18358816_ChIP-ChIP_MESCs_Mouse1.28347209
75* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.28068826
76POU5F1_16518401_ChIP-PET_MESCs_Mouse1.26708324
77HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.23962589
78E2F1_21310950_ChIP-Seq_MCF-7_Human1.22629906
79* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.20764221
80THAP11_20581084_ChIP-Seq_MESCs_Mouse1.19966334
81* EP300_21415370_ChIP-Seq_HL-1_Mouse1.19965980
82FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.19952723
83TBX3_20139965_ChIP-Seq_ESCs_Mouse1.19731229
84CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.19611674
85TBX3_20139965_ChIP-Seq_MESCs_Mouse1.17211886
86NANOG_18692474_ChIP-Seq_MESCs_Mouse1.16925671
87NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.16186521
88MYCN_18555785_ChIP-Seq_MESCs_Mouse1.15589891
89* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.15306792
90* SOX17_20123909_ChIP-Seq_XEN_Mouse1.14345947
91FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.11587781
92ELK1_19687146_ChIP-ChIP_HELA_Human1.11309021
93* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.11106152
94PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.10895606
95EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.10681942
96GATA1_26923725_Chip-Seq_HPCs_Mouse1.10504295
97EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.09515137
98SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.09332964
99SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.09332964
100NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.08208661
101NANOG_16518401_ChIP-PET_MESCs_Mouse1.06560668
102TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06153598
103POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.04566257
104OCT4_18692474_ChIP-Seq_MEFs_Mouse1.04229531
105SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.03140172
106MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.02763425
107DCP1A_22483619_ChIP-Seq_HELA_Human1.01447472
108ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.00800924
109* PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.97377878
110ESR1_15608294_ChIP-ChIP_MCF-7_Human0.96511331
111TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.96091124
112NANOG_21062744_ChIP-ChIP_HESCs_Human0.95971058
113JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93643073
114SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.93412059
115HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90370421
116JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89408017
117ZFP281_18757296_ChIP-ChIP_E14_Mouse0.89400504
118KLF4_18555785_ChIP-Seq_MESCs_Mouse0.87342922

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005503_abnormal_tendon_morphology6.75845790
2MP0008438_abnormal_cutaneous_collagen5.90217084
3MP0005275_abnormal_skin_tensile4.66853983
4MP0002254_reproductive_system_inflammat4.59491614
5MP0003705_abnormal_hypodermis_morpholog2.86774340
6MP0002282_abnormal_trachea_morphology2.79362979
7MP0004134_abnormal_chest_morphology2.71214931
8MP0005508_abnormal_skeleton_morphology2.49202939
9MP0003279_aneurysm2.37996124
10MP0002108_abnormal_muscle_morphology2.32148900
11MP0002933_joint_inflammation2.31874492
12MP0001958_emphysema2.20496359
13MP0009250_abnormal_appendicular_skeleto2.16479402
14MP0004272_abnormal_basement_membrane2.06986690
15MP0010352_gastrointestinal_tract_polyps2.06620309
16MP0003123_paternal_imprinting2.05999866
17MP0010030_abnormal_orbit_morphology2.00999548
18MP0003950_abnormal_plasma_membrane1.98201284
19MP0000163_abnormal_cartilage_morphology1.90417065
20MP0005023_abnormal_wound_healing1.76668243
21MP0003941_abnormal_skin_development1.74592200
22MP0004858_abnormal_nervous_system1.74451260
23MP0003566_abnormal_cell_adhesion1.72632150
24MP0005257_abnormal_intraocular_pressure1.68851282
25MP0010368_abnormal_lymphatic_system1.67961207
26MP0006054_spinal_hemorrhage1.64700581
27MP0009672_abnormal_birth_weight1.58792609
28MP0004510_myositis1.55404030
29MP0002115_abnormal_skeleton_extremities1.50055877
30MP0005390_skeleton_phenotype1.49669967
31MP0005367_renal/urinary_system_phenotyp1.49024396
32MP0000516_abnormal_urinary_system1.49024396
33MP0002249_abnormal_larynx_morphology1.45404038
34MP0000751_myopathy1.43476804
35MP0002060_abnormal_skin_morphology1.42888605
36MP0005623_abnormal_meninges_morphology1.37925651
37MP0002113_abnormal_skeleton_development1.37732079
38MP0004197_abnormal_fetal_growth/weight/1.37624890
39MP0003646_muscle_fatigue1.36113024
40MP0005076_abnormal_cell_differentiation1.34852391
41MP0003385_abnormal_body_wall1.32868550
42MP0003121_genomic_imprinting1.31832345
43MP0001542_abnormal_bone_strength1.29205530
44MP0003755_abnormal_palate_morphology1.25559275
45MP0003119_abnormal_digestive_system1.23875614
46MP0009384_cardiac_valve_regurgitation1.22805846
47MP0003567_abnormal_fetal_cardiomyocyte1.21493186
48MP0000762_abnormal_tongue_morphology1.20670316
49MP0000750_abnormal_muscle_regeneration1.20519492
50MP0004957_abnormal_blastocyst_morpholog1.19971824
51MP0001849_ear_inflammation1.19904396
52MP0004133_heterotaxia1.19798069
53MP0000432_abnormal_head_morphology1.18654139
54MP0000049_abnormal_middle_ear1.17952273
55MP0002896_abnormal_bone_mineralization1.16177119
56MP0004233_abnormal_muscle_weight1.15278907
57MP0010094_abnormal_chromosome_stability1.15184385
58MP0002697_abnormal_eye_size1.15008607
59MP0002089_abnormal_postnatal_growth/wei1.14232206
60MP0003890_abnormal_embryonic-extraembry1.12645740
61MP0008007_abnormal_cellular_replicative1.11846813
62MP0002116_abnormal_craniofacial_bone1.11841298
63MP0002109_abnormal_limb_morphology1.11452161
64MP0003077_abnormal_cell_cycle1.11132877
65MP0002111_abnormal_tail_morphology1.09456756
66MP0003937_abnormal_limbs/digits/tail_de1.06973002
67MP0009053_abnormal_anal_canal1.06719092
68MP0003111_abnormal_nucleus_morphology1.05805073
69MP0001243_abnormal_dermal_layer1.05198736
70MP0005595_abnormal_vascular_smooth1.02820967
71MP0002932_abnormal_joint_morphology1.01984231
72MP0003283_abnormal_digestive_organ0.99974700
73MP0001177_atelectasis0.99857258
74MP0001299_abnormal_eye_distance/0.99557422
75MP0003935_abnormal_craniofacial_develop0.98902757
76MP0009703_decreased_birth_body0.97425960
77MP0002114_abnormal_axial_skeleton0.96900781
78MP0008057_abnormal_DNA_replication0.96274756
79MP0001293_anophthalmia0.95481516
80MP0001915_intracranial_hemorrhage0.94139988
81MP0002233_abnormal_nose_morphology0.93826995
82MP0000537_abnormal_urethra_morphology0.91219311
83MP0003787_abnormal_imprinting0.91094198
84MP0003693_abnormal_embryo_hatching0.90065560
85MP0000350_abnormal_cell_proliferation0.89529112
86MP0005197_abnormal_uvea_morphology0.88943055
87MP0002332_abnormal_exercise_endurance0.88692493
88MP0005369_muscle_phenotype0.88522893
89MP0003984_embryonic_growth_retardation0.87659643
90MP0001175_abnormal_lung_morphology0.87500473
91MP0002295_abnormal_pulmonary_circulatio0.87202578
92MP0002086_abnormal_extraembryonic_tissu0.87067929
93MP0001730_embryonic_growth_arrest0.85885242
94MP0008058_abnormal_DNA_repair0.85860073
95MP0002925_abnormal_cardiovascular_devel0.85676479
96MP0001672_abnormal_embryogenesis/_devel0.85416745
97MP0005380_embryogenesis_phenotype0.85416745
98MP0002084_abnormal_developmental_patter0.85408517
99MP0002088_abnormal_embryonic_growth/wei0.85201632
100MP0001879_abnormal_lymphatic_vessel0.84766369
101MP0003115_abnormal_respiratory_system0.84359289
102MP0000733_abnormal_muscle_development0.84321073
103MP0003453_abnormal_keratinocyte_physiol0.84191248
104MP0002877_abnormal_melanocyte_morpholog0.84185762
105MP0003091_abnormal_cell_migration0.83794334
106MP0003186_abnormal_redox_activity0.83555418
107MP0002080_prenatal_lethality0.83329253
108MP0000428_abnormal_craniofacial_morphol0.83114357
109MP0008004_abnormal_stomach_pH0.82517383
110MP0000749_muscle_degeneration0.82103907
111MP0009697_abnormal_copulation0.81338838
112MP0005165_increased_susceptibility_to0.81312744
113MP0008932_abnormal_embryonic_tissue0.80397388
114MP0001286_abnormal_eye_development0.79705375
115MP0002085_abnormal_embryonic_tissue0.79200463
116MP0000534_abnormal_ureter_morphology0.78822075
117MP0003718_maternal_effect0.78451502
118MP0000343_altered_response_to0.77119099
119MP0003942_abnormal_urinary_system0.76794307
120MP0003795_abnormal_bone_structure0.76097466
121MP0004084_abnormal_cardiac_muscle0.76081941
122MP0001661_extended_life_span0.75183901
123MP0003448_altered_tumor_morphology0.74436752
124MP0010307_abnormal_tumor_latency0.73550254
125MP0005621_abnormal_cell_physiology0.73379944
126MP0008775_abnormal_heart_ventricle0.72762602
127MP0001697_abnormal_embryo_size0.72742110
128MP0000767_abnormal_smooth_muscle0.71586081
129MP0001614_abnormal_blood_vessel0.69350839

Predicted human phenotypes

RankGene SetZ-score
1Irregular epiphyses (HP:0010582)6.64831668
2Epiphyseal dysplasia (HP:0002656)6.51783603
3Vitreoretinal degeneration (HP:0000655)5.72815857
4Hypoplastic ischia (HP:0003175)5.19940349
5Small epiphyses (HP:0010585)4.65816479
6Abnormality of the ischium (HP:0003174)4.53895467
7Aplasia/Hypoplasia of the pubic bone (HP:0009104)4.46079177
8Mild short stature (HP:0003502)4.19878671
9Cupped ribs (HP:0000887)4.19264726
10Protrusio acetabuli (HP:0003179)4.17357748
11Neonatal short-limb short stature (HP:0008921)4.14655280
12Flat capital femoral epiphysis (HP:0003370)3.90659442
13Metaphyseal cupping (HP:0003021)3.74651774
14Delayed epiphyseal ossification (HP:0002663)3.70977887
15Genu varum (HP:0002970)3.63644588
16Cervical subluxation (HP:0003308)3.51534893
17Abnormality of femoral epiphyses (HP:0006499)3.36553680
18Abnormality involving the epiphyses of the lower limbs (HP:0006500)3.36553680
19Absent epiphyses (HP:0010577)3.36243769
20Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.36243769
21Abnormal tarsal ossification (HP:0008369)3.29631869
22Flat acetabular roof (HP:0003180)3.25919103
23Spastic diplegia (HP:0001264)3.23746355
24Premature rupture of membranes (HP:0001788)3.23503809
25Abnormality of dentin (HP:0010299)3.20050512
26Osteoarthritis (HP:0002758)3.16633433
27Selective tooth agenesis (HP:0001592)2.99972645
28Abnormality of the epiphysis of the femoral head (HP:0010574)2.98779324
29Patent foramen ovale (HP:0001655)2.86290134
30Cortical dysplasia (HP:0002539)2.83469633
31Coxa vara (HP:0002812)2.79468997
32Ankle contracture (HP:0006466)2.79011171
33Abnormality of the femoral head (HP:0003368)2.76624220
34Carpal bone hypoplasia (HP:0001498)2.75887499
35Limited hip movement (HP:0008800)2.75133601
36Flattened epiphyses (HP:0003071)2.74325686
37Osteolytic defects of the hand bones (HP:0009699)2.71617760
38Osteolytic defects of the phalanges of the hand (HP:0009771)2.71617760
39Platyspondyly (HP:0000926)2.71417964
40Bladder diverticulum (HP:0000015)2.71017106
41Hip contracture (HP:0003273)2.70425462
42Arthropathy (HP:0003040)2.67391060
43Atrophic scars (HP:0001075)2.65075809
44Abnormal vertebral ossification (HP:0100569)2.63095862
45Abnormal foot bone ossification (HP:0010675)2.61702227
46Abnormality of the proximal phalanges of the hand (HP:0009834)2.61068852
47Mitral valve prolapse (HP:0001634)2.60822552
48Abnormality of the vertebral endplates (HP:0005106)2.58732195
49Vascular tortuosity (HP:0004948)2.58490041
50Arterial tortuosity (HP:0005116)2.56453635
51Abnormality of the pubic bones (HP:0003172)2.52531043
52Type 1 muscle fiber predominance (HP:0003803)2.52029814
53Abnormality of the phalanges of the 2nd finger (HP:0009541)2.51213615
54Metaphyseal dysplasia (HP:0100255)2.50069668
55Nuclear cataract (HP:0100018)2.46503092
56Soft skin (HP:0000977)2.41756285
57Increased connective tissue (HP:0009025)2.41063488
58Mesomelia (HP:0003027)2.39838206
59Short femoral neck (HP:0100864)2.39269377
60Bowel diverticulosis (HP:0005222)2.37275977
61Thin ribs (HP:0000883)2.36330307
62Ectopia lentis (HP:0001083)2.36294638
63Genu recurvatum (HP:0002816)2.34632665
64Broad long bones (HP:0005622)2.34412182
65Broad phalanx (HP:0006009)2.33858352
66Beaking of vertebral bodies (HP:0004568)2.33514885
67Limited elbow extension (HP:0001377)2.33226330
68Septo-optic dysplasia (HP:0100842)2.32293706
69Protruding ear (HP:0000411)2.30748504
70Choanal stenosis (HP:0000452)2.30393827
71Slender build (HP:0001533)2.28558543
72Irregular vertebral endplates (HP:0003301)2.28321404
73Shoulder girdle muscle weakness (HP:0003547)2.25720684
74Vertebral clefting (HP:0008428)2.24804674
75Limb-girdle muscle weakness (HP:0003325)2.24121657
76Arnold-Chiari malformation (HP:0002308)2.23586280
77Pterygium (HP:0001059)2.23344246
78Abnormality of the acetabulum (HP:0003170)2.22872276
79Hypoplasia of the odontoid process (HP:0003311)2.22390772
80Fragile skin (HP:0001030)2.20445487
81Wrist flexion contracture (HP:0001239)2.18759002
82Fibular hypoplasia (HP:0003038)2.18735984
83Glossoptosis (HP:0000162)2.18362160
84Absent frontal sinuses (HP:0002688)2.18339880
85Generalized amyotrophy (HP:0003700)2.17356727
86Wormian bones (HP:0002645)2.16869247
87Vertebral hypoplasia (HP:0008417)2.16209587
88Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.16209587
89Biconcave vertebral bodies (HP:0004586)2.16025780
90Follicular hyperkeratosis (HP:0007502)2.15183151
91Spinal rigidity (HP:0003306)2.14565134
92Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.13000149
93Lower limb amyotrophy (HP:0007210)2.12801075
94Cerebral aneurysm (HP:0004944)2.08872838
95Stillbirth (HP:0003826)2.08523999
96Broad metatarsal (HP:0001783)2.08275540
97Coronal craniosynostosis (HP:0004440)2.06362630
98Distal lower limb muscle weakness (HP:0009053)2.04927638
99Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.04320441
100Thoracolumbar scoliosis (HP:0002944)2.04125427
101Fused cervical vertebrae (HP:0002949)2.03165279
102Pulmonary artery stenosis (HP:0004415)2.03115705
103Micromelia (HP:0002983)2.02603164
104Long clavicles (HP:0000890)2.02236566
105Delayed cranial suture closure (HP:0000270)2.02221801
106Abnormal delivery (HP:0001787)2.01362100
107Aortic aneurysm (HP:0004942)2.00797724
108Abnormality of the umbilical cord (HP:0010881)2.00739523
109Aplasia/Hypoplasia of the breasts (HP:0010311)2.00518139
110Ependymoma (HP:0002888)1.97458001
111Lumbar hyperlordosis (HP:0002938)1.97165571
112Broad thumb (HP:0011304)1.96775372
113Turricephaly (HP:0000262)1.95664328
114Broad phalanges of the hand (HP:0009768)1.95213891
115Aortic dissection (HP:0002647)1.94961809
116Abnormality of carpal bone ossification (HP:0006257)1.94585715
117Muscle fiber splitting (HP:0003555)1.94439633
118Myocardial infarction (HP:0001658)1.93611660
119Sprengel anomaly (HP:0000912)1.93100069
120Shallow orbits (HP:0000586)1.92619827
121Mildly elevated creatine phosphokinase (HP:0008180)1.92356774
122Hyperextensible skin (HP:0000974)1.91986279
123Abnormality of the hip-girdle musculature (HP:0001445)1.91482783
124Abnormality of the musculature of the pelvis (HP:0001469)1.91482783
125Natal tooth (HP:0000695)1.91279968
126Vertebral compression fractures (HP:0002953)1.90890875
127Abnormality of the odontoid process (HP:0003310)1.90615571
128Colon cancer (HP:0003003)1.88791130
129Ovoid vertebral bodies (HP:0003300)1.88598123
130Metaphyseal irregularity (HP:0003025)1.88398358
131Short nail (HP:0001799)1.87993956
132Joint laxity (HP:0001388)1.87951570
133Hypoventilation (HP:0002791)1.87769642
134Barrel-shaped chest (HP:0001552)1.87268606
135Broad finger (HP:0001500)1.86935102
136Waddling gait (HP:0002515)1.86503738
137Breast aplasia (HP:0100783)1.85899507
138Hypoplasia of the capital femoral epiphysis (HP:0003090)1.85596127
139Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.85094918
140Relative macrocephaly (HP:0004482)1.84972039
141Abnormal number of incisors (HP:0011064)1.84530101
142Blue sclerae (HP:0000592)1.83860904
143Broad palm (HP:0001169)1.83364692
144Breech presentation (HP:0001623)1.83228765
145Hand muscle atrophy (HP:0009130)1.82562338
146Abnormality of incisor morphology (HP:0011063)1.82434393
147Spinal cord compression (HP:0002176)1.81959538
148Distal upper limb amyotrophy (HP:0007149)1.81467748
149Upper limb amyotrophy (HP:0009129)1.81467748
150Joint stiffness (HP:0001387)1.81396224
151Overgrowth (HP:0001548)1.80621725
152Abnormal ossification of hand bones (HP:0005921)1.80200140
153Aplasia/Hypoplasia involving the vertebral column (HP:0008518)1.79279952
154Calcaneovalgus deformity (HP:0001848)1.78797927
155Aplasia involving bones of the extremities (HP:0009825)1.78434827
156Aplasia involving bones of the upper limbs (HP:0009823)1.78434827
157Aplasia of the phalanges of the hand (HP:0009802)1.78434827
158Stenosis of the external auditory canal (HP:0000402)1.78064993
159Pelvic girdle muscle weakness (HP:0003749)1.77852373
160Renal duplication (HP:0000075)1.77710141
161Facial cleft (HP:0002006)1.76469580
162Elbow flexion contracture (HP:0002987)1.75843714
163Bifid tongue (HP:0010297)1.74048560
164Increased variability in muscle fiber diameter (HP:0003557)1.73951349
165Upper limb muscle weakness (HP:0003484)1.72936733
166Dilatation of the ascending aorta (HP:0005111)1.71542813
167Short hallux (HP:0010109)1.70706325
168Overriding aorta (HP:0002623)1.69729298
169Abnormal lung lobation (HP:0002101)1.67857711
170Abnormality of the labia minora (HP:0012880)1.67279979
171Microglossia (HP:0000171)1.66888108
172Spinal cord lesions (HP:0100561)1.66545672
173Syringomyelia (HP:0003396)1.66545672
174Ulnar bowing (HP:0003031)1.66419338
175Maternal diabetes (HP:0009800)1.65996148
176Deformed tarsal bones (HP:0008119)1.65041359
177Bronchomalacia (HP:0002780)1.64957878
178Kyphoscoliosis (HP:0002751)1.64361280
179Long palpebral fissure (HP:0000637)1.63539779
180Nephroblastoma (Wilms tumor) (HP:0002667)1.63467285

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.86366269
2STK38L3.71370352
3MAP3K33.31770404
4TSSK62.86632212
5ACVR1B2.73180731
6TGFBR12.69785709
7EPHA22.67481217
8LATS12.57434337
9NME22.50424103
10CDK122.45960922
11VRK22.39307518
12CDC72.28725302
13AKT32.09511647
14LATS22.08595659
15PBK2.07520520
16TNIK2.06590689
17PDK21.96985563
18STK241.96277244
19MKNK21.91119843
20MOS1.83218543
21PTK21.83084196
22NTRK11.81032471
23ERBB31.80122169
24ZAK1.78908881
25IRAK31.75976438
26MKNK11.62654509
27TESK11.60335998
28LMTK21.59144934
29TAF11.55399665
30WEE11.54932093
31EPHA31.54424270
32BUB11.53792580
33PDGFRA1.52182612
34PIM21.51385106
35PLK21.50764180
36PLK41.48293826
37BMPR1B1.44722081
38NEK11.41865396
39STK31.39751603
40MET1.38623854
41PLK31.37684928
42ERBB41.33225171
43MST41.32820879
44CLK11.32313444
45BRD41.26120249
46CDK71.25455158
47RPS6KB21.20033293
48ABL21.11881735
49MELK1.09983574
50TTK1.09399900
51PAK41.07106165
52PRKG21.06321745
53PIM11.02369756
54PASK1.00955614
55BCR1.00538257
56TTN0.99470605
57ARAF0.98949936
58MAP3K60.97080477
59NME10.94966054
60EPHB20.94902718
61EIF2AK30.94047372
62TGFBR20.89413909
63TRIM280.87909016
64BMX0.87740878
65ATR0.83942456
66DYRK30.83820373
67EIF2AK10.83809580
68TRPM70.82749923
69PLK10.82532619
70PRPF4B0.82265053
71NEK60.82263338
72TAOK20.82168104
73SMG10.82081332
74SRPK10.80447618
75RPS6KA40.80417577
76TIE10.75351332
77CHEK10.75032553
78CDK180.74614619
79CDK150.71437191
80MAP3K90.69701388
81BRAF0.66991937
82EPHB10.66199550
83CDK11A0.65827777
84BRSK10.65474022
85FGFR10.65202269
86MTOR0.65002103
87EIF2AK20.64259610
88CSNK1G10.63912789
89CDK140.63692406
90AURKB0.63672072
91DMPK0.63487713
92GSK3A0.62383681
93DYRK1A0.61709167
94PRKD30.60759175
95NLK0.59215986
96CHEK20.59033394
97FER0.58859785
98ALK0.58564959
99BRSK20.57895237
100ROCK20.57535136
101PAK60.57263672
102MAPK10.55847337
103DYRK20.55133949
104PDGFRB0.54652016
105LIMK10.54590107
106ATM0.54547662
107PAK10.52736378
108ROCK10.51306152
109CDK20.50934617
110TESK20.50866428
111PAK20.50277343
112DAPK30.48801502
113STK160.48791328
114MAPK70.47223567
115TYRO30.46544407
116PDK30.44782571
117PDK40.44782571
118CDK60.44290285
119OBSCN0.43587891
120DAPK10.42546276
121FLT30.42219795
122CHUK0.41327734
123AKT10.40905242
124MYLK0.40088728
125CDK10.39993913
126CSNK1G20.39885071
127STK40.39818945
128YES10.39481086
129CSNK1G30.39072245
130NEK20.38996282
131RIPK10.37516572
132CAMK1G0.35022690
133CDC42BPA0.35006008
134MAP2K30.34505464
135CSNK1A1L0.34284788
136CDK40.30298255
137MAP3K80.30108210
138MAPKAPK30.29555478
139VRK10.29067805
140STK100.28698981
141CSNK1D0.28693409
142AURKA0.28189964

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.19768196
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.20095214
3Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005323.16693887
4One carbon pool by folate_Homo sapiens_hsa006702.97324895
5Protein digestion and absorption_Homo sapiens_hsa049742.95743726
6Mismatch repair_Homo sapiens_hsa034302.71396756
7DNA replication_Homo sapiens_hsa030302.68071713
8TGF-beta signaling pathway_Homo sapiens_hsa043502.52826325
9RNA transport_Homo sapiens_hsa030132.27179849
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.13869026
11Malaria_Homo sapiens_hsa051442.05779040
12Basal cell carcinoma_Homo sapiens_hsa052172.00684193
13Cell cycle_Homo sapiens_hsa041101.99700305
14Focal adhesion_Homo sapiens_hsa045101.98069332
15Hippo signaling pathway_Homo sapiens_hsa043901.96573775
16Cysteine and methionine metabolism_Homo sapiens_hsa002701.86992730
17Nucleotide excision repair_Homo sapiens_hsa034201.86881283
18Spliceosome_Homo sapiens_hsa030401.86131567
19Base excision repair_Homo sapiens_hsa034101.85523192
20Hedgehog signaling pathway_Homo sapiens_hsa043401.84924797
21Vitamin B6 metabolism_Homo sapiens_hsa007501.80406599
22Selenocompound metabolism_Homo sapiens_hsa004501.78534829
23Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.68763793
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.68004788
25MicroRNAs in cancer_Homo sapiens_hsa052061.63079504
26RNA polymerase_Homo sapiens_hsa030201.60558689
27Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.57054275
28PI3K-Akt signaling pathway_Homo sapiens_hsa041511.54556454
29* Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.52637298
30Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.50626309
31p53 signaling pathway_Homo sapiens_hsa041151.43770679
32Adherens junction_Homo sapiens_hsa045201.43580684
33Homologous recombination_Homo sapiens_hsa034401.37478345
34Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.37348303
35Proteoglycans in cancer_Homo sapiens_hsa052051.37171158
36Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.30617876
37Non-homologous end-joining_Homo sapiens_hsa034501.26990972
38AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.25664564
39Fanconi anemia pathway_Homo sapiens_hsa034601.25474787
40Pyruvate metabolism_Homo sapiens_hsa006201.20793209
41Proteasome_Homo sapiens_hsa030501.14635182
42mRNA surveillance pathway_Homo sapiens_hsa030151.11578557
43Basal transcription factors_Homo sapiens_hsa030221.11481183
44Dilated cardiomyopathy_Homo sapiens_hsa054141.11351588
45Small cell lung cancer_Homo sapiens_hsa052221.10610758
46Prion diseases_Homo sapiens_hsa050201.08144519
47HTLV-I infection_Homo sapiens_hsa051661.07596994
48Carbon metabolism_Homo sapiens_hsa012001.03869774
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02596200
50Legionellosis_Homo sapiens_hsa051341.02111002
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.01991360
52RNA degradation_Homo sapiens_hsa030181.01163103
53Steroid biosynthesis_Homo sapiens_hsa001000.98536584
54Bladder cancer_Homo sapiens_hsa052190.98471119
55Pathways in cancer_Homo sapiens_hsa052000.95823735
56Wnt signaling pathway_Homo sapiens_hsa043100.95562729
57Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.95127428
58Glutathione metabolism_Homo sapiens_hsa004800.95063095
59Pyrimidine metabolism_Homo sapiens_hsa002400.95017246
60Melanoma_Homo sapiens_hsa052180.92774724
61Amoebiasis_Homo sapiens_hsa051460.92527827
62Viral myocarditis_Homo sapiens_hsa054160.90864860
63HIF-1 signaling pathway_Homo sapiens_hsa040660.87959728
64Folate biosynthesis_Homo sapiens_hsa007900.87254510
65Galactose metabolism_Homo sapiens_hsa000520.85582929
66Viral carcinogenesis_Homo sapiens_hsa052030.85106384
67Fatty acid elongation_Homo sapiens_hsa000620.84684206
68Colorectal cancer_Homo sapiens_hsa052100.82282748
69TNF signaling pathway_Homo sapiens_hsa046680.79485565
70Arachidonic acid metabolism_Homo sapiens_hsa005900.77176227
71Shigellosis_Homo sapiens_hsa051310.74717650
72Epstein-Barr virus infection_Homo sapiens_hsa051690.73682679
73Tight junction_Homo sapiens_hsa045300.70310999
74Prostate cancer_Homo sapiens_hsa052150.69564933
75Purine metabolism_Homo sapiens_hsa002300.69109071
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68590129
77Notch signaling pathway_Homo sapiens_hsa043300.67558157
78Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67203973
79Oocyte meiosis_Homo sapiens_hsa041140.67198739
80Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66326136
81Regulation of actin cytoskeleton_Homo sapiens_hsa048100.66188383
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63617274
83Central carbon metabolism in cancer_Homo sapiens_hsa052300.61204852
84Pentose phosphate pathway_Homo sapiens_hsa000300.60728484
85Ribosome_Homo sapiens_hsa030100.59847685
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59765629
87Axon guidance_Homo sapiens_hsa043600.57015467
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.56019390
89Salmonella infection_Homo sapiens_hsa051320.53495288
90Thyroid cancer_Homo sapiens_hsa052160.52724575
91Fructose and mannose metabolism_Homo sapiens_hsa000510.52410345
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51231144
93N-Glycan biosynthesis_Homo sapiens_hsa005100.48338263
94Chronic myeloid leukemia_Homo sapiens_hsa052200.48235837
95Apoptosis_Homo sapiens_hsa042100.47864636
962-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.46978519
97Propanoate metabolism_Homo sapiens_hsa006400.46274416
98Mineral absorption_Homo sapiens_hsa049780.45741611
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.43232647
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43217666
101Vibrio cholerae infection_Homo sapiens_hsa051100.43211456
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43112210
103Systemic lupus erythematosus_Homo sapiens_hsa053220.41738740
104Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.41183660
105FoxO signaling pathway_Homo sapiens_hsa040680.40535574
106Gap junction_Homo sapiens_hsa045400.39668276
107Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39019305
108Biosynthesis of amino acids_Homo sapiens_hsa012300.37339367
109Lysine degradation_Homo sapiens_hsa003100.36561198
110* Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.35725727
111Hepatitis B_Homo sapiens_hsa051610.35660747
112African trypanosomiasis_Homo sapiens_hsa051430.35567493
113Arginine and proline metabolism_Homo sapiens_hsa003300.34876836
114Toxoplasmosis_Homo sapiens_hsa051450.34000936
115Protein export_Homo sapiens_hsa030600.33784126
116NOD-like receptor signaling pathway_Homo sapiens_hsa046210.33482323
117Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32776579
118Starch and sucrose metabolism_Homo sapiens_hsa005000.30305485
119Rap1 signaling pathway_Homo sapiens_hsa040150.29181611
120Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.29177029
121MAPK signaling pathway_Homo sapiens_hsa040100.28963120
122Herpes simplex infection_Homo sapiens_hsa051680.28758809
123Melanogenesis_Homo sapiens_hsa049160.28098965
124NF-kappa B signaling pathway_Homo sapiens_hsa040640.27865329
125Pancreatic cancer_Homo sapiens_hsa052120.26146339
126Phagosome_Homo sapiens_hsa041450.26145977
127Rheumatoid arthritis_Homo sapiens_hsa053230.25077927
128Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.24519303
129Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.24491037
130Ovarian steroidogenesis_Homo sapiens_hsa049130.23355635

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