

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 9.71847332 |
| 2 | * unsaturated fatty acid biosynthetic process (GO:0006636) | 8.84779723 |
| 3 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 8.59991731 |
| 4 | glutathione biosynthetic process (GO:0006750) | 8.36575685 |
| 5 | * glutathione metabolic process (GO:0006749) | 8.21367195 |
| 6 | peptide catabolic process (GO:0043171) | 8.00753265 |
| 7 | nonribosomal peptide biosynthetic process (GO:0019184) | 7.72180116 |
| 8 | detection of molecule of bacterial origin (GO:0032490) | 7.43192652 |
| 9 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 5.65282958 |
| 10 | mitochondrion distribution (GO:0048311) | 5.62548301 |
| 11 | response to pheromone (GO:0019236) | 5.56106014 |
| 12 | peptide biosynthetic process (GO:0043043) | 5.48818192 |
| 13 | * icosanoid metabolic process (GO:0006690) | 5.47148969 |
| 14 | * fatty acid derivative metabolic process (GO:1901568) | 5.47148969 |
| 15 | phosphatidylethanolamine metabolic process (GO:0046337) | 4.92446557 |
| 16 | mitochondrial calcium ion transport (GO:0006851) | 4.70200726 |
| 17 | * unsaturated fatty acid metabolic process (GO:0033559) | 4.69788949 |
| 18 | microglial cell activation (GO:0001774) | 4.63088780 |
| 19 | protein ADP-ribosylation (GO:0006471) | 4.52610050 |
| 20 | cerebellar Purkinje cell differentiation (GO:0021702) | 4.31729323 |
| 21 | positive regulation by symbiont of host defense response (GO:0052509) | 4.30646645 |
| 22 | modulation by symbiont of host defense response (GO:0052031) | 4.30646645 |
| 23 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.30646645 |
| 24 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.30646645 |
| 25 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.30646645 |
| 26 | modulation by symbiont of host immune response (GO:0052553) | 4.30646645 |
| 27 | serine family amino acid biosynthetic process (GO:0009070) | 4.21170977 |
| 28 | glutathione derivative biosynthetic process (GO:1901687) | 4.05137081 |
| 29 | glutathione derivative metabolic process (GO:1901685) | 4.05137081 |
| 30 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 4.00205690 |
| 31 | cellular modified amino acid catabolic process (GO:0042219) | 3.94128987 |
| 32 | * fatty acid biosynthetic process (GO:0006633) | 3.81239876 |
| 33 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.77880454 |
| 34 | protein K11-linked deubiquitination (GO:0035871) | 3.70416710 |
| 35 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.68981005 |
| 36 | alanine transport (GO:0032328) | 3.67419273 |
| 37 | sulfur amino acid biosynthetic process (GO:0000097) | 3.66983834 |
| 38 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.56289708 |
| 39 | macrophage activation involved in immune response (GO:0002281) | 3.54795845 |
| 40 | detection of external biotic stimulus (GO:0098581) | 3.47805257 |
| 41 | * peptide metabolic process (GO:0006518) | 3.42569775 |
| 42 | dopamine transport (GO:0015872) | 3.42360189 |
| 43 | macrophage activation (GO:0042116) | 3.38577561 |
| 44 | interferon-gamma secretion (GO:0072643) | 3.35761466 |
| 45 | protein prenylation (GO:0018342) | 3.31786269 |
| 46 | prenylation (GO:0097354) | 3.31786269 |
| 47 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.31733880 |
| 48 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.30875607 |
| 49 | neuronal action potential (GO:0019228) | 3.27332213 |
| 50 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 3.21989542 |
| 51 | glutamate metabolic process (GO:0006536) | 3.21880300 |
| 52 | androgen biosynthetic process (GO:0006702) | 3.08771427 |
| 53 | epithelial cilium movement (GO:0003351) | 3.07018859 |
| 54 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.04211222 |
| 55 | histone H3-K9 demethylation (GO:0033169) | 2.99325587 |
| 56 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.97995482 |
| 57 | protein targeting to Golgi (GO:0000042) | 2.94239813 |
| 58 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.91009384 |
| 59 | detection of biotic stimulus (GO:0009595) | 2.89162242 |
| 60 | negative regulation of neurotransmitter transport (GO:0051589) | 2.88882258 |
| 61 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.87526423 |
| 62 | histone H3-K36 demethylation (GO:0070544) | 2.85595985 |
| 63 | establishment of protein localization to Golgi (GO:0072600) | 2.85225863 |
| 64 | proline transport (GO:0015824) | 2.84218350 |
| 65 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.83015373 |
| 66 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.83015373 |
| 67 | neural tube formation (GO:0001841) | 2.80357446 |
| 68 | cell communication involved in cardiac conduction (GO:0086065) | 2.78416129 |
| 69 | positive regulation of RNA splicing (GO:0033120) | 2.76623080 |
| 70 | T-helper 1 type immune response (GO:0042088) | 2.76177172 |
| 71 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.75055655 |
| 72 | response to host immune response (GO:0052572) | 2.75055655 |
| 73 | regulation of membrane depolarization (GO:0003254) | 2.70994771 |
| 74 | amide biosynthetic process (GO:0043604) | 2.70846598 |
| 75 | response to acidic pH (GO:0010447) | 2.69210858 |
| 76 | histone lysine demethylation (GO:0070076) | 2.63710823 |
| 77 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.62248089 |
| 78 | prepulse inhibition (GO:0060134) | 2.61021407 |
| 79 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.59028988 |
| 80 | gastrulation with mouth forming second (GO:0001702) | 2.57550814 |
| 81 | Golgi to endosome transport (GO:0006895) | 2.56636151 |
| 82 | phospholipid translocation (GO:0045332) | 2.53617856 |
| 83 | lipid translocation (GO:0034204) | 2.53617856 |
| 84 | histone demethylation (GO:0016577) | 2.52215822 |
| 85 | histone mRNA catabolic process (GO:0071044) | 2.50663922 |
| 86 | myelin assembly (GO:0032288) | 2.49409080 |
| 87 | response to host (GO:0075136) | 2.45982258 |
| 88 | response to host defenses (GO:0052200) | 2.45982258 |
| 89 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.45982258 |
| 90 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.45308490 |
| 91 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.45172504 |
| 92 | I-kappaB phosphorylation (GO:0007252) | 2.43358245 |
| 93 | glycine transport (GO:0015816) | 2.41472661 |
| 94 | membrane depolarization during action potential (GO:0086010) | 2.33639958 |
| 95 | oocyte development (GO:0048599) | 2.33566133 |
| 96 | * leukotriene biosynthetic process (GO:0019370) | 19.3535413 |
| 97 | * leukotriene metabolic process (GO:0006691) | 13.1566681 |
| 98 | cysteine metabolic process (GO:0006534) | 10.9526495 |
| 99 | * icosanoid biosynthetic process (GO:0046456) | 10.6934722 |
| 100 | * fatty acid derivative biosynthetic process (GO:1901570) | 10.6934722 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.21010070 |
| 2 | GATA1_22025678_ChIP-Seq_K562_Human | 3.20293100 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.80630199 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.72502038 |
| 5 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.53166272 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.49112698 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.29429346 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.22869948 |
| 9 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.18895340 |
| 10 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 2.17611330 |
| 11 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.17611330 |
| 12 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.16125788 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.04809840 |
| 14 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.01706477 |
| 15 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 2.00649085 |
| 16 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.99307833 |
| 17 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.94430844 |
| 18 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.91873034 |
| 19 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.90553450 |
| 20 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.85593710 |
| 21 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.85222804 |
| 22 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.85222804 |
| 23 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.78639230 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.77821907 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.74029569 |
| 26 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.71894272 |
| 27 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.71885568 |
| 28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.65702556 |
| 29 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.58068005 |
| 30 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.56264925 |
| 31 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.56098191 |
| 32 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.55614094 |
| 33 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.50780525 |
| 34 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.49730711 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.47380304 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.45341991 |
| 37 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.45041305 |
| 38 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.44223442 |
| 39 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.43579840 |
| 40 | TP53_16413492_ChIP-PET_HCT116_Human | 1.43306073 |
| 41 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.39122005 |
| 42 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.38457121 |
| 43 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.38314787 |
| 44 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36693908 |
| 45 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.34754215 |
| 46 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.33688879 |
| 47 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.33637789 |
| 48 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.33180893 |
| 49 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.28990001 |
| 50 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.26889184 |
| 51 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.26559608 |
| 52 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.24884580 |
| 53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.24507711 |
| 54 | STAT3_23295773_ChIP-Seq_U87_Human | 1.23717646 |
| 55 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.22080665 |
| 56 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.21992749 |
| 57 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.21013394 |
| 58 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.20228237 |
| 59 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.20223073 |
| 60 | MYB_26560356_Chip-Seq_TH2_Human | 1.19979017 |
| 61 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.19561077 |
| 62 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.19512378 |
| 63 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.18808019 |
| 64 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.18598584 |
| 65 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.16937547 |
| 66 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.16679542 |
| 67 | AR_25329375_ChIP-Seq_VCAP_Human | 1.15663893 |
| 68 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.15397522 |
| 69 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.14639728 |
| 70 | TCF4_23295773_ChIP-Seq_U87_Human | 1.13870163 |
| 71 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.11721623 |
| 72 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.11527233 |
| 73 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.10411905 |
| 74 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.09125414 |
| 75 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.07910417 |
| 76 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.07774686 |
| 77 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.07224336 |
| 78 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.07039637 |
| 79 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.07015954 |
| 80 | GATA3_26560356_Chip-Seq_TH1_Human | 1.05825288 |
| 81 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.05160587 |
| 82 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.04392869 |
| 83 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.02692923 |
| 84 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02182786 |
| 85 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01880421 |
| 86 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.01605801 |
| 87 | CJUN_26792858_Chip-Seq_BT549_Human | 1.00662353 |
| 88 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.99958235 |
| 89 | RXR_22108803_ChIP-Seq_LS180_Human | 0.99303336 |
| 90 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.98764294 |
| 91 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.98706860 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98162766 |
| 93 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.97520947 |
| 94 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.97435152 |
| 95 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.97292385 |
| 96 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.97292385 |
| 97 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.95490864 |
| 98 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94843453 |
| 99 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.93986105 |
| 100 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.92025283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003183_abnormal_peptide_metabolism | 8.23059841 |
| 2 | MP0003195_calcinosis | 6.08214337 |
| 3 | MP0002163_abnormal_gland_morphology | 6.06841559 |
| 4 | MP0005379_endocrine/exocrine_gland_phen | 4.31104301 |
| 5 | MP0002736_abnormal_nociception_after | 4.29798458 |
| 6 | MP0002089_abnormal_postnatal_growth/wei | 3.94874704 |
| 7 | MP0008995_early_reproductive_senescence | 3.74809606 |
| 8 | MP0002822_catalepsy | 3.70625344 |
| 9 | MP0000613_abnormal_salivary_gland | 3.61084637 |
| 10 | MP0000569_abnormal_digit_pigmentation | 3.53953738 |
| 11 | MP0001968_abnormal_touch/_nociception | 3.05899456 |
| 12 | MP0005220_abnormal_exocrine_pancreas | 2.74666000 |
| 13 | MP0000371_diluted_coat_color | 2.61453257 |
| 14 | MP0003300_gastrointestinal_ulcer | 1.93670477 |
| 15 | MP0005410_abnormal_fertilization | 1.84502183 |
| 16 | MP0003656_abnormal_erythrocyte_physiolo | 1.69755933 |
| 17 | MP0003011_delayed_dark_adaptation | 1.49573360 |
| 18 | MP0002277_abnormal_respiratory_mucosa | 1.48977763 |
| 19 | MP0008877_abnormal_DNA_methylation | 1.34710238 |
| 20 | MP0003959_abnormal_lean_body | 1.31338235 |
| 21 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.29433584 |
| 22 | MP0000858_altered_metastatic_potential | 1.22814458 |
| 23 | MP0003878_abnormal_ear_physiology | 1.19493236 |
| 24 | MP0005377_hearing/vestibular/ear_phenot | 1.19493236 |
| 25 | MP0004742_abnormal_vestibular_system | 1.18988262 |
| 26 | MP0004484_altered_response_of | 1.17442626 |
| 27 | MP0003252_abnormal_bile_duct | 1.12075233 |
| 28 | MP0002009_preneoplasia | 1.10753559 |
| 29 | MP0005647_abnormal_sex_gland | 1.07389146 |
| 30 | MP0004264_abnormal_extraembryonic_tissu | 1.06819507 |
| 31 | MP0009785_altered_susceptibility_to | 1.05091188 |
| 32 | MP0002075_abnormal_coat/hair_pigmentati | 1.04724150 |
| 33 | MP0002733_abnormal_thermal_nociception | 1.03765191 |
| 34 | MP0004019_abnormal_vitamin_homeostasis | 1.02698347 |
| 35 | MP0001835_abnormal_antigen_presentation | 0.99962509 |
| 36 | MP0003698_abnormal_male_reproductive | 0.96374106 |
| 37 | MP0008872_abnormal_physiological_respon | 0.95561175 |
| 38 | MP0008057_abnormal_DNA_replication | 0.95085018 |
| 39 | MP0003690_abnormal_glial_cell | 0.91880013 |
| 40 | MP0001800_abnormal_humoral_immune | 0.91005672 |
| 41 | MP0004142_abnormal_muscle_tone | 0.90944817 |
| 42 | MP0002876_abnormal_thyroid_physiology | 0.90285154 |
| 43 | MP0005332_abnormal_amino_acid | 0.89008132 |
| 44 | MP0001756_abnormal_urination | 0.85659398 |
| 45 | MP0005171_absent_coat_pigmentation | 0.84670410 |
| 46 | MP0005645_abnormal_hypothalamus_physiol | 0.83988542 |
| 47 | MP0000015_abnormal_ear_pigmentation | 0.83618281 |
| 48 | MP0005310_abnormal_salivary_gland | 0.83615545 |
| 49 | MP0002735_abnormal_chemical_nociception | 0.82398315 |
| 50 | MP0001929_abnormal_gametogenesis | 0.78095422 |
| 51 | MP0001186_pigmentation_phenotype | 0.78090579 |
| 52 | MP0008260_abnormal_autophagy | 0.76901240 |
| 53 | MP0003828_pulmonary_edema | 0.75966194 |
| 54 | MP0003786_premature_aging | 0.73333847 |
| 55 | MP0002229_neurodegeneration | 0.72836622 |
| 56 | MP0002067_abnormal_sensory_capabilities | 0.72782822 |
| 57 | MP0003045_fibrosis | 0.72687750 |
| 58 | MP0005671_abnormal_response_to | 0.70778310 |
| 59 | MP0003943_abnormal_hepatobiliary_system | 0.70610509 |
| 60 | MP0002272_abnormal_nervous_system | 0.69460243 |
| 61 | MP0001119_abnormal_female_reproductive | 0.67419088 |
| 62 | MP0000470_abnormal_stomach_morphology | 0.66377152 |
| 63 | MP0005551_abnormal_eye_electrophysiolog | 0.66360678 |
| 64 | MP0002332_abnormal_exercise_endurance | 0.65901309 |
| 65 | MP0000689_abnormal_spleen_morphology | 0.64436121 |
| 66 | MP0000163_abnormal_cartilage_morphology | 0.64396744 |
| 67 | MP0001970_abnormal_pain_threshold | 0.63851240 |
| 68 | MP0005666_abnormal_adipose_tissue | 0.62807961 |
| 69 | MP0005375_adipose_tissue_phenotype | 0.62690024 |
| 70 | MP0001145_abnormal_male_reproductive | 0.62241645 |
| 71 | MP0003724_increased_susceptibility_to | 0.62040503 |
| 72 | MP0002723_abnormal_immune_serum | 0.61193018 |
| 73 | MP0002168_other_aberrant_phenotype | 0.60861146 |
| 74 | MP0004883_abnormal_blood_vessel | 0.60184227 |
| 75 | MP0000716_abnormal_immune_system | 0.60020238 |
| 76 | MP0004924_abnormal_behavior | 0.59241277 |
| 77 | MP0005386_behavior/neurological_phenoty | 0.59241277 |
| 78 | MP0001944_abnormal_pancreas_morphology | 0.59129828 |
| 79 | MP0002166_altered_tumor_susceptibility | 0.59058651 |
| 80 | MP0010386_abnormal_urinary_bladder | 0.58667777 |
| 81 | MP0002928_abnormal_bile_duct | 0.58080016 |
| 82 | MP0001765_abnormal_ion_homeostasis | 0.56452698 |
| 83 | MP0000013_abnormal_adipose_tissue | 0.56281113 |
| 84 | MP0000653_abnormal_sex_gland | 0.55567050 |
| 85 | MP0005075_abnormal_melanosome_morpholog | 0.53421630 |
| 86 | MP0003763_abnormal_thymus_physiology | 0.53417596 |
| 87 | MP0002115_abnormal_skeleton_extremities | 0.53404844 |
| 88 | MP0002108_abnormal_muscle_morphology | 0.52941638 |
| 89 | MP0005408_hypopigmentation | 0.50563076 |
| 90 | MP0005174_abnormal_tail_pigmentation | 0.50379595 |
| 91 | MP0002398_abnormal_bone_marrow | 0.49369074 |
| 92 | MP0001663_abnormal_digestive_system | 0.49338177 |
| 93 | MP0002452_abnormal_antigen_presenting | 0.49153836 |
| 94 | MP0001819_abnormal_immune_cell | 0.48504046 |
| 95 | MP0002420_abnormal_adaptive_immunity | 0.47946841 |
| 96 | MP0000639_abnormal_adrenal_gland | 0.47773073 |
| 97 | MP0002751_abnormal_autonomic_nervous | 0.47726912 |
| 98 | MP0005334_abnormal_fat_pad | 0.47593337 |
| 99 | MP0004381_abnormal_hair_follicle | 0.46751718 |
| 100 | MP0003787_abnormal_imprinting | 0.46053648 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Vertebral arch anomaly (HP:0008438) | 7.27545007 |
| 2 | J-shaped sella turcica (HP:0002680) | 6.43662333 |
| 3 | Diastasis recti (HP:0001540) | 6.29086677 |
| 4 | Carpal bone hypoplasia (HP:0001498) | 6.18471292 |
| 5 | Thoracolumbar scoliosis (HP:0002944) | 5.88779760 |
| 6 | Broad alveolar ridges (HP:0000187) | 5.53122120 |
| 7 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 5.30121389 |
| 8 | Absent/shortened dynein arms (HP:0200106) | 5.30121389 |
| 9 | Abnormality of liposaccharide metabolism (HP:0010968) | 5.22702275 |
| 10 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 5.22702275 |
| 11 | Abnormality of glycolipid metabolism (HP:0010969) | 5.22702275 |
| 12 | Abnormality of the lumbar spine (HP:0100712) | 5.04048488 |
| 13 | Broad ribs (HP:0000885) | 5.01446162 |
| 14 | Flat acetabular roof (HP:0003180) | 4.63702748 |
| 15 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 4.49469503 |
| 16 | Deformed sella turcica (HP:0002681) | 4.15293619 |
| 17 | Thoracic kyphosis (HP:0002942) | 4.03187925 |
| 18 | Nonprogressive disorder (HP:0003680) | 4.00613086 |
| 19 | Recurrent bronchitis (HP:0002837) | 3.96874882 |
| 20 | Aortic regurgitation (HP:0001659) | 3.94213168 |
| 21 | Flared iliac wings (HP:0002869) | 3.84452488 |
| 22 | Thickened calvaria (HP:0002684) | 3.66751610 |
| 23 | Beaking of vertebral bodies (HP:0004568) | 3.39821536 |
| 24 | Protuberant abdomen (HP:0001538) | 3.38270240 |
| 25 | Genetic anticipation (HP:0003743) | 3.24162531 |
| 26 | Palpebral edema (HP:0100540) | 3.23495157 |
| 27 | Visual hallucinations (HP:0002367) | 3.17017373 |
| 28 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.14014730 |
| 29 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.14014730 |
| 30 | Abnormality of the sella turcica (HP:0002679) | 3.03692901 |
| 31 | Abnormal ciliary motility (HP:0012262) | 2.96112959 |
| 32 | Abnormality of the thoracic spine (HP:0100711) | 2.92822006 |
| 33 | Aplasia/Hypoplasia of the scapulae (HP:0006713) | 2.76639738 |
| 34 | Hypoplastic scapulae (HP:0000882) | 2.76639738 |
| 35 | Abnormality of the fovea (HP:0000493) | 2.76520552 |
| 36 | Abnormality of the alveolar ridges (HP:0006477) | 2.76267720 |
| 37 | Slow saccadic eye movements (HP:0000514) | 2.76087164 |
| 38 | Acne (HP:0001061) | 2.72973287 |
| 39 | Bronchitis (HP:0012387) | 2.65168767 |
| 40 | Severe visual impairment (HP:0001141) | 2.59423870 |
| 41 | Severe global developmental delay (HP:0011344) | 2.55513986 |
| 42 | Gonadotropin excess (HP:0000837) | 2.51162705 |
| 43 | Mucopolysacchariduria (HP:0008155) | 2.50721042 |
| 44 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.50721042 |
| 45 | Hypoplasia of the odontoid process (HP:0003311) | 2.49714865 |
| 46 | Corneal dystrophy (HP:0001131) | 2.37524910 |
| 47 | Postural instability (HP:0002172) | 2.29637497 |
| 48 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.29522643 |
| 49 | Recurrent pneumonia (HP:0006532) | 2.27733358 |
| 50 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.26292367 |
| 51 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.26292367 |
| 52 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.26292367 |
| 53 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.25820032 |
| 54 | Craniofacial hyperostosis (HP:0004493) | 2.22876216 |
| 55 | Homocystinuria (HP:0002156) | 2.19886642 |
| 56 | Abnormality of homocysteine metabolism (HP:0010919) | 2.19886642 |
| 57 | Dysostosis multiplex (HP:0000943) | 2.17281034 |
| 58 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.17249877 |
| 59 | Abnormality of the odontoid process (HP:0003310) | 2.17205674 |
| 60 | Death in childhood (HP:0003819) | 2.15485269 |
| 61 | Hypoplasia of the fovea (HP:0007750) | 2.14832165 |
| 62 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.14832165 |
| 63 | Anomalous pulmonary venous return (HP:0010772) | 2.10718060 |
| 64 | Hoarse voice (HP:0001609) | 2.09358682 |
| 65 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.04639150 |
| 66 | Wide intermamillary distance (HP:0006610) | 2.03822079 |
| 67 | Pathologic fracture (HP:0002756) | 2.03649995 |
| 68 | Abnormality of macular pigmentation (HP:0008002) | 2.00073703 |
| 69 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.98203862 |
| 70 | Clumsiness (HP:0002312) | 1.97919078 |
| 71 | Microcytic anemia (HP:0001935) | 1.97776347 |
| 72 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 1.97632341 |
| 73 | Short ribs (HP:0000773) | 1.95118913 |
| 74 | Spontaneous hematomas (HP:0007420) | 1.93590431 |
| 75 | Cavernous hemangioma (HP:0001048) | 1.89852461 |
| 76 | Cranial hyperostosis (HP:0004437) | 1.89268644 |
| 77 | Attenuation of retinal blood vessels (HP:0007843) | 1.89250861 |
| 78 | Lack of skin elasticity (HP:0100679) | 1.88504724 |
| 79 | Central scotoma (HP:0000603) | 1.87280730 |
| 80 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.85806294 |
| 81 | Recurrent cutaneous fungal infections (HP:0011370) | 1.85806294 |
| 82 | Ovoid vertebral bodies (HP:0003300) | 1.84103284 |
| 83 | T lymphocytopenia (HP:0005403) | 1.82930839 |
| 84 | Infertility (HP:0000789) | 1.82928767 |
| 85 | Abnormality of the pulmonary veins (HP:0011718) | 1.81840959 |
| 86 | Abnormality of the wing of the ilium (HP:0011867) | 1.80016235 |
| 87 | Abnormality of the aortic arch (HP:0012303) | 1.77845007 |
| 88 | Hypoplasia of the thymus (HP:0000778) | 1.76954058 |
| 89 | Gonadal dysgenesis (HP:0000133) | 1.70531359 |
| 90 | Pancreatic fibrosis (HP:0100732) | 1.70489514 |
| 91 | Pustule (HP:0200039) | 1.68297337 |
| 92 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.66523040 |
| 93 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.66523040 |
| 94 | Decreased central vision (HP:0007663) | 1.65047134 |
| 95 | Hyperkalemia (HP:0002153) | 1.64600641 |
| 96 | Recurrent lower respiratory tract infections (HP:0002783) | 1.62500014 |
| 97 | Abnormality of T cell number (HP:0011839) | 1.62342604 |
| 98 | Tongue fasciculations (HP:0001308) | 1.60904554 |
| 99 | Progressive cerebellar ataxia (HP:0002073) | 1.60201069 |
| 100 | Nausea (HP:0002018) | 1.60160555 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BLK | 4.15277227 |
| 2 | MAP3K2 | 3.84979760 |
| 3 | FRK | 3.52849175 |
| 4 | CAMKK2 | 3.49179891 |
| 5 | NTRK3 | 3.45724492 |
| 6 | MAP2K3 | 3.26811597 |
| 7 | PIK3CG | 2.35311515 |
| 8 | WNK1 | 2.32447518 |
| 9 | PINK1 | 2.24399774 |
| 10 | PRPF4B | 1.84779949 |
| 11 | DYRK3 | 1.84344391 |
| 12 | YES1 | 1.83495061 |
| 13 | TSSK6 | 1.77776242 |
| 14 | MAP3K6 | 1.76332678 |
| 15 | IRAK4 | 1.72752674 |
| 16 | IRAK1 | 1.71236600 |
| 17 | MAP3K13 | 1.63622461 |
| 18 | STK38L | 1.59910107 |
| 19 | SGK2 | 1.57573695 |
| 20 | EPHA3 | 1.51621934 |
| 21 | CAMK4 | 1.49442105 |
| 22 | MAP3K5 | 1.47849115 |
| 23 | TXK | 1.46129494 |
| 24 | RIPK4 | 1.43607920 |
| 25 | PTK2B | 1.42884049 |
| 26 | GRK6 | 1.40230816 |
| 27 | TYK2 | 1.35812636 |
| 28 | GRK5 | 1.33405603 |
| 29 | MAP3K7 | 1.32834126 |
| 30 | CAMKK1 | 1.27261671 |
| 31 | IRAK2 | 1.21965767 |
| 32 | DYRK1B | 1.21919216 |
| 33 | SGK494 | 1.21794393 |
| 34 | SGK223 | 1.21794393 |
| 35 | HIPK2 | 1.20003719 |
| 36 | MAP2K6 | 1.16299022 |
| 37 | IKBKE | 1.16110861 |
| 38 | BRD4 | 1.14632231 |
| 39 | FES | 1.10950094 |
| 40 | TEC | 1.09063881 |
| 41 | ACVR1B | 1.06605537 |
| 42 | FGR | 1.01089370 |
| 43 | MAP3K3 | 0.99790054 |
| 44 | SYK | 0.99225141 |
| 45 | BRSK2 | 0.97701351 |
| 46 | PIM1 | 0.95437815 |
| 47 | GRK7 | 0.93946587 |
| 48 | PLK2 | 0.93563186 |
| 49 | CDK6 | 0.91663893 |
| 50 | NLK | 0.90983056 |
| 51 | FGFR3 | 0.88974213 |
| 52 | UHMK1 | 0.88879896 |
| 53 | TGFBR2 | 0.88639735 |
| 54 | WNK3 | 0.85949570 |
| 55 | ADRBK1 | 0.84149491 |
| 56 | NEK9 | 0.82630143 |
| 57 | ADRBK2 | 0.81522376 |
| 58 | MAP2K4 | 0.76325979 |
| 59 | STK11 | 0.75069828 |
| 60 | SGK3 | 0.74576449 |
| 61 | INSRR | 0.73007329 |
| 62 | TAF1 | 0.71634299 |
| 63 | LYN | 0.71400331 |
| 64 | RPS6KA4 | 0.70325224 |
| 65 | MINK1 | 0.69829744 |
| 66 | STK4 | 0.69596438 |
| 67 | PDK1 | 0.69446820 |
| 68 | SGK1 | 0.69371837 |
| 69 | IKBKB | 0.68090651 |
| 70 | RPS6KB2 | 0.66543082 |
| 71 | NTRK2 | 0.65184616 |
| 72 | JAK1 | 0.64356231 |
| 73 | BMPR2 | 0.62418114 |
| 74 | RET | 0.61292615 |
| 75 | RPS6KA6 | 0.59035593 |
| 76 | CSK | 0.55562707 |
| 77 | JAK2 | 0.54979946 |
| 78 | MELK | 0.54957315 |
| 79 | MATK | 0.54561905 |
| 80 | LCK | 0.53458742 |
| 81 | SIK2 | 0.51181243 |
| 82 | PLK4 | 0.50495536 |
| 83 | ICK | 0.49796203 |
| 84 | LATS1 | 0.49696111 |
| 85 | ZAP70 | 0.49546965 |
| 86 | TAOK3 | 0.48939246 |
| 87 | PRKG1 | 0.47809229 |
| 88 | WNK4 | 0.47283955 |
| 89 | DDR2 | 0.47180038 |
| 90 | STK38 | 0.44733204 |
| 91 | TLK1 | 0.43228875 |
| 92 | MAP3K1 | 0.43017133 |
| 93 | MAP4K1 | 0.42422881 |
| 94 | PDPK1 | 0.42205116 |
| 95 | DYRK1A | 0.41166828 |
| 96 | KIT | 0.40517119 |
| 97 | CHUK | 0.39667894 |
| 98 | RPS6KC1 | 0.33972971 |
| 99 | RPS6KL1 | 0.33972971 |
| 100 | HCK | 0.33365180 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 7.19229107 |
| 2 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 10.5710391 |
| 3 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.76104742 |
| 4 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.54457955 |
| 5 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.52297859 |
| 6 | Renin secretion_Homo sapiens_hsa04924 | 1.35083342 |
| 7 | Taste transduction_Homo sapiens_hsa04742 | 1.35004623 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.32767171 |
| 9 | Nicotine addiction_Homo sapiens_hsa05033 | 1.32620038 |
| 10 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.27441510 |
| 11 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.25975717 |
| 12 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.23931016 |
| 13 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.23211922 |
| 14 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.08858369 |
| 15 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.06430086 |
| 16 | Long-term potentiation_Homo sapiens_hsa04720 | 1.00485081 |
| 17 | Cocaine addiction_Homo sapiens_hsa05030 | 1.00449771 |
| 18 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.98131048 |
| 19 | Morphine addiction_Homo sapiens_hsa05032 | 0.94183350 |
| 20 | Leishmaniasis_Homo sapiens_hsa05140 | 0.93873179 |
| 21 | Tuberculosis_Homo sapiens_hsa05152 | 0.90181143 |
| 22 | Malaria_Homo sapiens_hsa05144 | 0.86410525 |
| 23 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.83316535 |
| 24 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.78580324 |
| 25 | GABAergic synapse_Homo sapiens_hsa04727 | 0.73402864 |
| 26 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.72727897 |
| 27 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.70361069 |
| 28 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.68961396 |
| 29 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.67973140 |
| 30 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.67136354 |
| 31 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.66392768 |
| 32 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.65003756 |
| 33 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.64711044 |
| 34 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.64380663 |
| 35 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.63982740 |
| 36 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.63956504 |
| 37 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.61724220 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60143007 |
| 39 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.59987471 |
| 40 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.59986146 |
| 41 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59104101 |
| 42 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.59088352 |
| 43 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.58839965 |
| 44 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.58172106 |
| 45 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.56851220 |
| 46 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56738914 |
| 47 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.56104288 |
| 48 | Platelet activation_Homo sapiens_hsa04611 | 0.55558187 |
| 49 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.55380616 |
| 50 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.52891074 |
| 51 | Olfactory transduction_Homo sapiens_hsa04740 | 0.52801545 |
| 52 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.52640876 |
| 53 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.52302986 |
| 54 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.50694396 |
| 55 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.49603413 |
| 56 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.49037784 |
| 57 | Axon guidance_Homo sapiens_hsa04360 | 0.48363625 |
| 58 | Influenza A_Homo sapiens_hsa05164 | 0.47611540 |
| 59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.45729608 |
| 60 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.44767668 |
| 61 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.44207317 |
| 62 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.43763098 |
| 63 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.41262547 |
| 64 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.41242153 |
| 65 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.41144344 |
| 66 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.41044101 |
| 67 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.40512272 |
| 68 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.40503181 |
| 69 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.39607320 |
| 70 | Measles_Homo sapiens_hsa05162 | 0.39509220 |
| 71 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.39421261 |
| 72 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.38155278 |
| 73 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.37779420 |
| 74 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.37593207 |
| 75 | Circadian rhythm_Homo sapiens_hsa04710 | 0.37082145 |
| 76 | Prostate cancer_Homo sapiens_hsa05215 | 0.37026146 |
| 77 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.36773315 |
| 78 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.36281220 |
| 79 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.35367491 |
| 80 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.35012258 |
| 81 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.34882621 |
| 82 | Alcoholism_Homo sapiens_hsa05034 | 0.34177041 |
| 83 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.33448484 |
| 84 | Salivary secretion_Homo sapiens_hsa04970 | 0.32767799 |
| 85 | Phototransduction_Homo sapiens_hsa04744 | 0.32722345 |
| 86 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.31864744 |
| 87 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.31520777 |
| 88 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.30825707 |
| 89 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.30710862 |
| 90 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.30527441 |
| 91 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.30147892 |
| 92 | Hepatitis B_Homo sapiens_hsa05161 | 0.29169867 |
| 93 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.28483078 |
| 94 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.27563157 |
| 95 | Gap junction_Homo sapiens_hsa04540 | 0.25929660 |
| 96 | ABC transporters_Homo sapiens_hsa02010 | 0.25556961 |
| 97 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.25178670 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.24371260 |
| 99 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.23434327 |
| 100 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.23135074 |

