

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 7.33912093 |
| 2 | negative T cell selection (GO:0043383) | 6.65534140 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.52059254 |
| 4 | negative thymic T cell selection (GO:0045060) | 5.72571177 |
| 5 | positive T cell selection (GO:0043368) | 5.67550775 |
| 6 | negative regulation of cell killing (GO:0031342) | 5.49994820 |
| 7 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.49994820 |
| 8 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.48958446 |
| 9 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.44567825 |
| 10 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.12335776 |
| 11 | cellular response to interleukin-15 (GO:0071350) | 4.95339602 |
| 12 | regulation of gamma-delta T cell activation (GO:0046643) | 4.91173198 |
| 13 | alpha-beta T cell differentiation (GO:0046632) | 4.85721209 |
| 14 | T cell selection (GO:0045058) | 4.81214746 |
| 15 | regulation of regulatory T cell differentiation (GO:0045589) | 4.75909610 |
| 16 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.71101856 |
| 17 | response to interleukin-15 (GO:0070672) | 4.63504734 |
| 18 | thymic T cell selection (GO:0045061) | 4.62862196 |
| 19 | positive thymic T cell selection (GO:0045059) | 4.52519220 |
| 20 | regulation of T cell tolerance induction (GO:0002664) | 4.50330995 |
| 21 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.49670306 |
| 22 | positive regulation of humoral immune response (GO:0002922) | 4.45255709 |
| 23 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.44281190 |
| 24 | positive regulation of tolerance induction (GO:0002645) | 4.43479342 |
| 25 | alpha-beta T cell activation (GO:0046631) | 4.23302918 |
| 26 | tolerance induction (GO:0002507) | 4.19515060 |
| 27 | interferon-gamma production (GO:0032609) | 4.15231237 |
| 28 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.12093913 |
| 29 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.06147698 |
| 30 | response to muramyl dipeptide (GO:0032495) | 3.89249784 |
| 31 | T cell differentiation involved in immune response (GO:0002292) | 3.86593963 |
| 32 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.86593963 |
| 33 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.86593963 |
| 34 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.86139021 |
| 35 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.82850119 |
| 36 | regulation of tolerance induction (GO:0002643) | 3.81352672 |
| 37 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.80776332 |
| 38 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.79995805 |
| 39 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.73516091 |
| 40 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.70565039 |
| 41 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.69497811 |
| 42 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.69079608 |
| 43 | regulation of cellular extravasation (GO:0002691) | 3.60139107 |
| 44 | defense response to protozoan (GO:0042832) | 3.59631500 |
| 45 | myeloid dendritic cell differentiation (GO:0043011) | 3.58734935 |
| 46 | positive regulation of antigen processing and presentation (GO:0002579) | 3.52638719 |
| 47 | myeloid dendritic cell activation (GO:0001773) | 3.46246679 |
| 48 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.45837800 |
| 49 | positive regulation of isotype switching (GO:0045830) | 3.44100298 |
| 50 | positive regulation of DNA recombination (GO:0045911) | 3.39694928 |
| 51 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.37023314 |
| 52 | regulation of germinal center formation (GO:0002634) | 3.35895807 |
| 53 | T cell migration (GO:0072678) | 3.34976312 |
| 54 | regulation of interleukin-1 secretion (GO:0050704) | 3.28384779 |
| 55 | regulation of hypersensitivity (GO:0002883) | 3.25597200 |
| 56 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.20118151 |
| 57 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.19341102 |
| 58 | T cell differentiation (GO:0030217) | 3.18630174 |
| 59 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.18122531 |
| 60 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.16766005 |
| 61 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.16743529 |
| 62 | regulation of response to interferon-gamma (GO:0060330) | 3.15276405 |
| 63 | T cell receptor signaling pathway (GO:0050852) | 3.14544526 |
| 64 | leukocyte aggregation (GO:0070486) | 3.13401130 |
| 65 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 3.12322297 |
| 66 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.09826532 |
| 67 | response to protozoan (GO:0001562) | 3.08658001 |
| 68 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.07709708 |
| 69 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.06038794 |
| 70 | activated T cell proliferation (GO:0050798) | 3.04787957 |
| 71 | negative regulation of bone resorption (GO:0045779) | 3.02110873 |
| 72 | negative regulation of T cell apoptotic process (GO:0070233) | 3.02012085 |
| 73 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.01587862 |
| 74 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.01587862 |
| 75 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.99514852 |
| 76 | mature B cell differentiation involved in immune response (GO:0002313) | 2.98745173 |
| 77 | positive regulation of B cell mediated immunity (GO:0002714) | 2.98607411 |
| 78 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.98607411 |
| 79 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.98575698 |
| 80 | negative regulation of T cell mediated immunity (GO:0002710) | 2.98275487 |
| 81 | histone H3-K36 demethylation (GO:0070544) | 2.97435262 |
| 82 | regulation of B cell differentiation (GO:0045577) | 2.95640153 |
| 83 | positive regulation of interleukin-12 production (GO:0032735) | 2.94853776 |
| 84 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.94839284 |
| 85 | adaptation of signaling pathway (GO:0023058) | 2.90702847 |
| 86 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.90121997 |
| 87 | T-helper cell differentiation (GO:0042093) | 2.90121997 |
| 88 | regulation of interleukin-1 beta production (GO:0032651) | 2.89680216 |
| 89 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.89576824 |
| 90 | regulation of thymocyte apoptotic process (GO:0070243) | 2.88213422 |
| 91 | dendritic cell differentiation (GO:0097028) | 2.87774581 |
| 92 | regulation of antigen processing and presentation (GO:0002577) | 2.87339593 |
| 93 | immunoglobulin mediated immune response (GO:0016064) | 2.85368150 |
| 94 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.85152818 |
| 95 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.85152818 |
| 96 | lymphocyte migration (GO:0072676) | 2.84042126 |
| 97 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.82067043 |
| 98 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.80739710 |
| 99 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.80151038 |
| 100 | cellular response to exogenous dsRNA (GO:0071360) | 2.80025660 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 7.59333561 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.06384756 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.08228489 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.34321781 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.84274051 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.70947543 |
| 7 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.29888555 |
| 8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.80166552 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 2.65647214 |
| 10 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.63985296 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.60859909 |
| 12 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.58090437 |
| 13 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.41107646 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.31998311 |
| 15 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.21720495 |
| 16 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.18090254 |
| 17 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.16150880 |
| 18 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.15306415 |
| 19 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.12913691 |
| 20 | MAF_26560356_Chip-Seq_TH1_Human | 2.11813602 |
| 21 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.05545393 |
| 22 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.05002057 |
| 23 | GATA1_22025678_ChIP-Seq_K562_Human | 1.99166321 |
| 24 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.97728879 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.97050235 |
| 26 | MYB_26560356_Chip-Seq_TH1_Human | 1.95215074 |
| 27 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.93217943 |
| 28 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.92686218 |
| 29 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.87665576 |
| 30 | GATA3_26560356_Chip-Seq_TH2_Human | 1.82427112 |
| 31 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79651712 |
| 32 | UTX_26944678_Chip-Seq_JUKART_Human | 1.73183695 |
| 33 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.70964206 |
| 34 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.67087868 |
| 35 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.65283553 |
| 36 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59825228 |
| 37 | MAF_26560356_Chip-Seq_TH2_Human | 1.59503630 |
| 38 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.59215793 |
| 39 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.52798602 |
| 40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.49003671 |
| 41 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.48933168 |
| 42 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.41110745 |
| 43 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.39167825 |
| 44 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.37986848 |
| 45 | SPI1_23127762_ChIP-Seq_K562_Human | 1.37979495 |
| 46 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.32633985 |
| 47 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.31042293 |
| 48 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.30008363 |
| 49 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.29973499 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26603742 |
| 51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.24323792 |
| 52 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.15964362 |
| 53 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.14529140 |
| 54 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.13258041 |
| 55 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.12564191 |
| 56 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09590623 |
| 57 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.08216565 |
| 58 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07912375 |
| 59 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.07793082 |
| 60 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.06695231 |
| 61 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.03382127 |
| 62 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.02929277 |
| 63 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.02776707 |
| 64 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.02663320 |
| 65 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.02169314 |
| 66 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.00983018 |
| 67 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93232454 |
| 68 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.92819105 |
| 69 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92353328 |
| 70 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.88757478 |
| 71 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.88469087 |
| 72 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.87938351 |
| 73 | P300_27268052_Chip-Seq_Bcells_Human | 0.86147529 |
| 74 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.85091312 |
| 75 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.83844035 |
| 76 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.82872821 |
| 77 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.79632507 |
| 78 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.77818831 |
| 79 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.76346887 |
| 80 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.76206592 |
| 81 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.75101201 |
| 82 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.74508297 |
| 83 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.73245447 |
| 84 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.72711640 |
| 85 | GATA3_26560356_Chip-Seq_TH1_Human | 0.70860855 |
| 86 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.70238728 |
| 87 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.70184205 |
| 88 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.69795665 |
| 89 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.67800985 |
| 90 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.67243298 |
| 91 | MYC_22102868_ChIP-Seq_BL_Human | 0.67212856 |
| 92 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.66754690 |
| 93 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.66300720 |
| 94 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.65672185 |
| 95 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.65337401 |
| 96 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.64853965 |
| 97 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.62772356 |
| 98 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.62425363 |
| 99 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.61827797 |
| 100 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.61684873 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.75185612 |
| 2 | MP0003724_increased_susceptibility_to | 4.35865163 |
| 3 | MP0001835_abnormal_antigen_presentation | 4.03642794 |
| 4 | MP0003763_abnormal_thymus_physiology | 3.66707563 |
| 5 | MP0002166_altered_tumor_susceptibility | 3.61168090 |
| 6 | MP0003436_decreased_susceptibility_to | 3.54550403 |
| 7 | MP0001873_stomach_inflammation | 3.25373019 |
| 8 | MP0005000_abnormal_immune_tolerance | 3.06498696 |
| 9 | MP0001800_abnormal_humoral_immune | 2.81666447 |
| 10 | MP0001348_abnormal_lacrimal_gland | 2.80289742 |
| 11 | MP0000685_abnormal_immune_system | 2.75115729 |
| 12 | MP0002009_preneoplasia | 2.72610851 |
| 13 | MP0005167_abnormal_blood-brain_barrier | 2.71120078 |
| 14 | MP0009785_altered_susceptibility_to | 2.54282401 |
| 15 | MP0002006_tumorigenesis | 2.53996022 |
| 16 | MP0009333_abnormal_splenocyte_physiolog | 2.53842913 |
| 17 | MP0002933_joint_inflammation | 2.50541954 |
| 18 | MP0002723_abnormal_immune_serum | 2.45973329 |
| 19 | MP0002420_abnormal_adaptive_immunity | 2.39631265 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 2.36735918 |
| 21 | MP0001790_abnormal_immune_system | 2.36676919 |
| 22 | MP0005387_immune_system_phenotype | 2.36676919 |
| 23 | MP0001819_abnormal_immune_cell | 2.35441969 |
| 24 | MP0002452_abnormal_antigen_presenting | 2.26092471 |
| 25 | MP0002419_abnormal_innate_immunity | 2.23774616 |
| 26 | MP0010155_abnormal_intestine_physiology | 2.13888174 |
| 27 | MP0002405_respiratory_system_inflammati | 2.11817922 |
| 28 | MP0003866_abnormal_defecation | 2.05410495 |
| 29 | MP0005025_abnormal_response_to | 2.05110763 |
| 30 | MP0001533_abnormal_skeleton_physiology | 1.88567002 |
| 31 | MP0000703_abnormal_thymus_morphology | 1.85207051 |
| 32 | MP0000465_gastrointestinal_hemorrhage | 1.82848566 |
| 33 | MP0002163_abnormal_gland_morphology | 1.80894202 |
| 34 | MP0003172_abnormal_lysosome_physiology | 1.80643639 |
| 35 | MP0002398_abnormal_bone_marrow | 1.78139477 |
| 36 | MP0006082_CNS_inflammation | 1.73479694 |
| 37 | MP0000716_abnormal_immune_system | 1.71709206 |
| 38 | MP0000569_abnormal_digit_pigmentation | 1.70291824 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.64853966 |
| 40 | MP0002722_abnormal_immune_system | 1.62008506 |
| 41 | MP0003828_pulmonary_edema | 1.61787589 |
| 42 | MP0005310_abnormal_salivary_gland | 1.58762346 |
| 43 | MP0001346_abnormal_lacrimal_gland | 1.54826549 |
| 44 | MP0000015_abnormal_ear_pigmentation | 1.48982061 |
| 45 | MP0001845_abnormal_inflammatory_respons | 1.41946567 |
| 46 | MP0002429_abnormal_blood_cell | 1.38405626 |
| 47 | MP0003656_abnormal_erythrocyte_physiolo | 1.38263071 |
| 48 | MP0003252_abnormal_bile_duct | 1.34746306 |
| 49 | MP0004782_abnormal_surfactant_physiolog | 1.34240967 |
| 50 | MP0003303_peritoneal_inflammation | 1.27753611 |
| 51 | MP0004947_skin_inflammation | 1.20854829 |
| 52 | MP0008872_abnormal_physiological_respon | 1.16455477 |
| 53 | MP0009840_abnormal_foam_cell | 1.13261236 |
| 54 | MP0009764_decreased_sensitivity_to | 1.04620885 |
| 55 | MP0001663_abnormal_digestive_system | 1.04557987 |
| 56 | MP0005464_abnormal_platelet_physiology | 1.03150746 |
| 57 | MP0002254_reproductive_system_inflammat | 1.00163027 |
| 58 | MP0008469_abnormal_protein_level | 0.99928116 |
| 59 | MP0002138_abnormal_hepatobiliary_system | 0.97923863 |
| 60 | MP0009278_abnormal_bone_marrow | 0.92699242 |
| 61 | MP0002332_abnormal_exercise_endurance | 0.89764654 |
| 62 | MP0001958_emphysema | 0.88392078 |
| 63 | MP0002998_abnormal_bone_remodeling | 0.88048935 |
| 64 | MP0000249_abnormal_blood_vessel | 0.84643495 |
| 65 | MP0001851_eye_inflammation | 0.84151430 |
| 66 | MP0003690_abnormal_glial_cell | 0.83862944 |
| 67 | MP0004381_abnormal_hair_follicle | 0.81629171 |
| 68 | MP0004130_abnormal_muscle_cell | 0.78536592 |
| 69 | MP0005379_endocrine/exocrine_gland_phen | 0.74895826 |
| 70 | MP0002693_abnormal_pancreas_physiology | 0.73274497 |
| 71 | MP0001879_abnormal_lymphatic_vessel | 0.72938748 |
| 72 | MP0003646_muscle_fatigue | 0.72358467 |
| 73 | MP0002876_abnormal_thyroid_physiology | 0.72103028 |
| 74 | MP0010307_abnormal_tumor_latency | 0.71342404 |
| 75 | MP0005390_skeleton_phenotype | 0.70903777 |
| 76 | MP0002133_abnormal_respiratory_system | 0.65220819 |
| 77 | MP0005388_respiratory_system_phenotype | 0.65220819 |
| 78 | MP0001765_abnormal_ion_homeostasis | 0.64336783 |
| 79 | MP0003191_abnormal_cellular_cholesterol | 0.64274208 |
| 80 | MP0005645_abnormal_hypothalamus_physiol | 0.63644452 |
| 81 | MP0005381_digestive/alimentary_phenotyp | 0.61440348 |
| 82 | MP0003950_abnormal_plasma_membrane | 0.61237762 |
| 83 | MP0004883_abnormal_blood_vessel | 0.60862895 |
| 84 | MP0002928_abnormal_bile_duct | 0.60681351 |
| 85 | MP0005075_abnormal_melanosome_morpholog | 0.60535001 |
| 86 | MP0001501_abnormal_sleep_pattern | 0.60436328 |
| 87 | MP0003300_gastrointestinal_ulcer | 0.60083176 |
| 88 | MP0001661_extended_life_span | 0.58847308 |
| 89 | MP0005174_abnormal_tail_pigmentation | 0.58132503 |
| 90 | MP0003795_abnormal_bone_structure | 0.57936166 |
| 91 | MP0006072_abnormal_retinal_apoptosis | 0.56207891 |
| 92 | MP0005166_decreased_susceptibility_to | 0.52951222 |
| 93 | MP0008789_abnormal_olfactory_epithelium | 0.51919448 |
| 94 | MP0003448_altered_tumor_morphology | 0.50694114 |
| 95 | MP0001919_abnormal_reproductive_system | 0.49387495 |
| 96 | MP0000613_abnormal_salivary_gland | 0.48769470 |
| 97 | MP0004036_abnormal_muscle_relaxation | 0.48279368 |
| 98 | MP0002019_abnormal_tumor_incidence | 0.46469141 |
| 99 | MP0000470_abnormal_stomach_morphology | 0.45478166 |
| 100 | MP0002136_abnormal_kidney_physiology | 0.44955855 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 5.83795774 |
| 2 | Abnormality of T cell number (HP:0011839) | 5.38620599 |
| 3 | Stomatitis (HP:0010280) | 5.17793342 |
| 4 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.05546573 |
| 5 | Congenital, generalized hypertrichosis (HP:0004540) | 5.05325632 |
| 6 | Renal cortical cysts (HP:0000803) | 4.52457718 |
| 7 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.26273763 |
| 8 | Recurrent cutaneous fungal infections (HP:0011370) | 4.26273763 |
| 9 | Abnormality of secondary sexual hair (HP:0009888) | 4.18479698 |
| 10 | Abnormality of the axillary hair (HP:0100134) | 4.18479698 |
| 11 | Abnormality of T cells (HP:0002843) | 4.16547716 |
| 12 | Fair hair (HP:0002286) | 4.09689690 |
| 13 | Dry hair (HP:0011359) | 4.05790564 |
| 14 | Recurrent fungal infections (HP:0002841) | 4.01704407 |
| 15 | Pustule (HP:0200039) | 3.85845680 |
| 16 | Myositis (HP:0100614) | 3.81238710 |
| 17 | Mesangial abnormality (HP:0001966) | 3.70242676 |
| 18 | IgG deficiency (HP:0004315) | 3.67178515 |
| 19 | Gastrointestinal infarctions (HP:0005244) | 3.54201281 |
| 20 | Generalized hypopigmentation of hair (HP:0011358) | 3.40976659 |
| 21 | Severe combined immunodeficiency (HP:0004430) | 3.33351563 |
| 22 | Papilledema (HP:0001085) | 3.32504014 |
| 23 | Asplenia (HP:0001746) | 3.06720146 |
| 24 | Joint swelling (HP:0001386) | 3.05525560 |
| 25 | IgA deficiency (HP:0002720) | 3.01897513 |
| 26 | Optic neuritis (HP:0100653) | 2.99679888 |
| 27 | Retrobulbar optic neuritis (HP:0100654) | 2.99679888 |
| 28 | Abnormality of the fingertips (HP:0001211) | 2.99653200 |
| 29 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.99470803 |
| 30 | Hemoptysis (HP:0002105) | 2.98225403 |
| 31 | Abnormality of the renal cortex (HP:0011035) | 2.91089139 |
| 32 | Chronic diarrhea (HP:0002028) | 2.91025837 |
| 33 | Eosinophilia (HP:0001880) | 2.88500740 |
| 34 | Abnormality of eosinophils (HP:0001879) | 2.88366012 |
| 35 | Increased IgM level (HP:0003496) | 2.83103186 |
| 36 | Spontaneous hematomas (HP:0007420) | 2.80921323 |
| 37 | Leukocytosis (HP:0001974) | 2.80217180 |
| 38 | Abnormality of T cell physiology (HP:0011840) | 2.80159963 |
| 39 | Granulocytopenia (HP:0001913) | 2.79329729 |
| 40 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.77879780 |
| 41 | Autoimmune hemolytic anemia (HP:0001890) | 2.76853166 |
| 42 | Orchitis (HP:0100796) | 2.73977843 |
| 43 | Thyroiditis (HP:0100646) | 2.72744823 |
| 44 | Stomach cancer (HP:0012126) | 2.64647262 |
| 45 | Autoimmune thrombocytopenia (HP:0001973) | 2.63236428 |
| 46 | Recurrent viral infections (HP:0004429) | 2.61082709 |
| 47 | Pulmonary infiltrates (HP:0002113) | 2.56719697 |
| 48 | Ridged nail (HP:0001807) | 2.56497382 |
| 49 | Chest pain (HP:0100749) | 2.54137052 |
| 50 | Keratoconjunctivitis (HP:0001096) | 2.50100182 |
| 51 | Abnormality of the prostate (HP:0008775) | 2.47928378 |
| 52 | Meningitis (HP:0001287) | 2.47747164 |
| 53 | Obstructive lung disease (HP:0006536) | 2.46807701 |
| 54 | Chronic obstructive pulmonary disease (HP:0006510) | 2.46807701 |
| 55 | Combined immunodeficiency (HP:0005387) | 2.46222931 |
| 56 | Lymphopenia (HP:0001888) | 2.40284996 |
| 57 | Hematochezia (HP:0002573) | 2.39120467 |
| 58 | Prolonged bleeding time (HP:0003010) | 2.37576511 |
| 59 | Hypoplasia of the thymus (HP:0000778) | 2.37228687 |
| 60 | IgM deficiency (HP:0002850) | 2.35365093 |
| 61 | Recurrent skin infections (HP:0001581) | 2.32664353 |
| 62 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.21375996 |
| 63 | Cheilitis (HP:0100825) | 2.19311165 |
| 64 | Eczematoid dermatitis (HP:0000976) | 2.17765255 |
| 65 | Abnormality of B cell number (HP:0010975) | 2.16865881 |
| 66 | Pulmonary embolism (HP:0002204) | 2.16842914 |
| 67 | Hypergammaglobulinemia (HP:0010702) | 2.15564630 |
| 68 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.15219687 |
| 69 | Metaphyseal dysplasia (HP:0100255) | 2.14209230 |
| 70 | Woolly hair (HP:0002224) | 2.13528617 |
| 71 | Panhypogammaglobulinemia (HP:0003139) | 2.13421710 |
| 72 | Vasculitis (HP:0002633) | 2.13392757 |
| 73 | Recurrent bronchitis (HP:0002837) | 2.11639614 |
| 74 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.11520718 |
| 75 | Concave nail (HP:0001598) | 2.07737380 |
| 76 | Hypotrichosis (HP:0001006) | 2.07240451 |
| 77 | Microcytic anemia (HP:0001935) | 2.07183054 |
| 78 | Prominent nose (HP:0000448) | 2.06335743 |
| 79 | Epistaxis (HP:0000421) | 2.05164954 |
| 80 | Methylmalonic acidemia (HP:0002912) | 2.02401393 |
| 81 | Abnormality of macrophages (HP:0004311) | 1.95869815 |
| 82 | Prostate neoplasm (HP:0100787) | 1.94713752 |
| 83 | Hypochromic anemia (HP:0001931) | 1.94586600 |
| 84 | Tinnitus (HP:0000360) | 1.93782125 |
| 85 | Anorexia (HP:0002039) | 1.91979074 |
| 86 | Clumsiness (HP:0002312) | 1.89537238 |
| 87 | Keratoconjunctivitis sicca (HP:0001097) | 1.88003441 |
| 88 | Hyperlipoproteinemia (HP:0010980) | 1.86022959 |
| 89 | Mediastinal lymphadenopathy (HP:0100721) | 1.84791098 |
| 90 | Gingival bleeding (HP:0000225) | 1.84527568 |
| 91 | Increased IgE level (HP:0003212) | 1.84514905 |
| 92 | Increased cerebral lipofuscin (HP:0011813) | 1.84442805 |
| 93 | Recurrent abscess formation (HP:0002722) | 1.82395676 |
| 94 | Arterial thrombosis (HP:0004420) | 1.82382913 |
| 95 | Fatigue (HP:0012378) | 1.81139252 |
| 96 | Encephalitis (HP:0002383) | 1.78750238 |
| 97 | Polydipsia (HP:0001959) | 1.78378332 |
| 98 | Abnormal drinking behavior (HP:0030082) | 1.78378332 |
| 99 | Gangrene (HP:0100758) | 1.78338567 |
| 100 | Glomerulopathy (HP:0100820) | 1.77402938 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.91998574 |
| 2 | TIE1 | 4.59846984 |
| 3 | RIPK1 | 3.01485768 |
| 4 | MAP2K2 | 3.00991044 |
| 5 | TGFBR2 | 2.99627914 |
| 6 | RIPK4 | 2.89160057 |
| 7 | MAP4K1 | 2.62687655 |
| 8 | GRK7 | 2.32417701 |
| 9 | STK10 | 2.25461178 |
| 10 | IKBKE | 2.23485830 |
| 11 | FES | 2.19037221 |
| 12 | CAMKK2 | 2.10550635 |
| 13 | TEC | 1.86682838 |
| 14 | MAP3K14 | 1.79436461 |
| 15 | MOS | 1.78248554 |
| 16 | KIT | 1.70584375 |
| 17 | CDK12 | 1.66609180 |
| 18 | FRK | 1.65767306 |
| 19 | GRK6 | 1.57689773 |
| 20 | EIF2AK2 | 1.56422005 |
| 21 | BRD4 | 1.55949290 |
| 22 | ITK | 1.55000120 |
| 23 | TLK1 | 1.53518306 |
| 24 | IKBKB | 1.51689111 |
| 25 | BMPR1B | 1.51197068 |
| 26 | JAK3 | 1.47685405 |
| 27 | TBK1 | 1.36318407 |
| 28 | SYK | 1.35502153 |
| 29 | LCK | 1.34107800 |
| 30 | CSK | 1.31991016 |
| 31 | CAMK1D | 1.30533253 |
| 32 | GRK1 | 1.29422683 |
| 33 | HCK | 1.13365677 |
| 34 | BTK | 1.13232384 |
| 35 | ZAP70 | 1.13219554 |
| 36 | BMX | 1.12666220 |
| 37 | GRK5 | 1.12216378 |
| 38 | MAP3K13 | 1.10426041 |
| 39 | MAP3K12 | 1.07665968 |
| 40 | TNK2 | 1.06050689 |
| 41 | FLT3 | 1.01829434 |
| 42 | TESK2 | 1.01324531 |
| 43 | NTRK2 | 0.99738461 |
| 44 | CAMKK1 | 0.99494377 |
| 45 | JAK1 | 0.96094159 |
| 46 | BLK | 0.95639211 |
| 47 | LYN | 0.95108574 |
| 48 | BMPR2 | 0.94319617 |
| 49 | FGFR2 | 0.92482091 |
| 50 | FGFR3 | 0.88268152 |
| 51 | JAK2 | 0.86038425 |
| 52 | ACVR1B | 0.85552242 |
| 53 | ERN1 | 0.84867314 |
| 54 | AKT3 | 0.79323378 |
| 55 | TYK2 | 0.76697791 |
| 56 | MAP3K7 | 0.75493071 |
| 57 | PIM1 | 0.71247261 |
| 58 | MAPK11 | 0.68998004 |
| 59 | CDK8 | 0.65710933 |
| 60 | PRKCQ | 0.64616974 |
| 61 | TRPM7 | 0.60068591 |
| 62 | MAP2K1 | 0.58289467 |
| 63 | ADRBK1 | 0.58135702 |
| 64 | KDR | 0.57266655 |
| 65 | DYRK1A | 0.56274585 |
| 66 | CDK9 | 0.55314488 |
| 67 | NEK6 | 0.53857674 |
| 68 | PRKD2 | 0.53555148 |
| 69 | TGFBR1 | 0.52735055 |
| 70 | TAOK3 | 0.51535852 |
| 71 | EIF2AK3 | 0.50685391 |
| 72 | NME1 | 0.50348875 |
| 73 | PDK1 | 0.49007464 |
| 74 | CSF1R | 0.47573566 |
| 75 | EGFR | 0.45732767 |
| 76 | IGF1R | 0.45527909 |
| 77 | FYN | 0.45215169 |
| 78 | MARK3 | 0.45019461 |
| 79 | PTK2B | 0.43627603 |
| 80 | MAPK12 | 0.42460323 |
| 81 | LMTK2 | 0.41847869 |
| 82 | MAPK7 | 0.40890311 |
| 83 | NUAK1 | 0.40577809 |
| 84 | MST4 | 0.40493807 |
| 85 | PRKAA2 | 0.40472726 |
| 86 | RPS6KA4 | 0.40055689 |
| 87 | IRAK4 | 0.37636796 |
| 88 | CDK6 | 0.36550002 |
| 89 | ABL1 | 0.35384537 |
| 90 | WNK1 | 0.33673075 |
| 91 | TYRO3 | 0.27919876 |
| 92 | CAMK1G | 0.27454713 |
| 93 | PASK | 0.25172847 |
| 94 | ADRBK2 | 0.24756677 |
| 95 | CDK4 | 0.24674947 |
| 96 | WNK4 | 0.22312801 |
| 97 | ERBB3 | 0.22247483 |
| 98 | EIF2AK1 | 0.21511871 |
| 99 | MAPK4 | 0.21450393 |
| 100 | INSR | 0.21199595 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.07690333 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.75505615 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.40313953 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.07334540 |
| 5 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.97349019 |
| 6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.85389747 |
| 7 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.74286304 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.62815123 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.57397869 |
| 10 | Leishmaniasis_Homo sapiens_hsa05140 | 2.48157485 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.38108103 |
| 12 | Measles_Homo sapiens_hsa05162 | 2.24960641 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.23982166 |
| 14 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.23154736 |
| 15 | Asthma_Homo sapiens_hsa05310 | 2.10332670 |
| 16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.03467928 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.97470903 |
| 18 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.95921019 |
| 19 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.94378630 |
| 20 | Viral myocarditis_Homo sapiens_hsa05416 | 1.86473207 |
| 21 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.80590589 |
| 22 | Malaria_Homo sapiens_hsa05144 | 1.68733136 |
| 23 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.65398735 |
| 24 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.64734044 |
| 25 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.61741984 |
| 26 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.53125461 |
| 27 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.47449097 |
| 28 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.44276791 |
| 29 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.41677342 |
| 30 | Tuberculosis_Homo sapiens_hsa05152 | 1.39888681 |
| 31 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.38453360 |
| 32 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.12488749 |
| 33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.10443608 |
| 34 | Influenza A_Homo sapiens_hsa05164 | 1.07753099 |
| 35 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.07545272 |
| 36 | RNA polymerase_Homo sapiens_hsa03020 | 1.01247823 |
| 37 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.00724841 |
| 38 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.98889445 |
| 39 | Legionellosis_Homo sapiens_hsa05134 | 0.96535478 |
| 40 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.96190731 |
| 41 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.91086195 |
| 42 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.90485977 |
| 43 | ABC transporters_Homo sapiens_hsa02010 | 0.87973112 |
| 44 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.80551208 |
| 45 | HTLV-I infection_Homo sapiens_hsa05166 | 0.80375063 |
| 46 | Hepatitis B_Homo sapiens_hsa05161 | 0.70917357 |
| 47 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.68861560 |
| 48 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.67909308 |
| 49 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.67816464 |
| 50 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.67044382 |
| 51 | Platelet activation_Homo sapiens_hsa04611 | 0.66983178 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.66292673 |
| 53 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.65075595 |
| 54 | Proteasome_Homo sapiens_hsa03050 | 0.58043734 |
| 55 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.56721351 |
| 56 | Hepatitis C_Homo sapiens_hsa05160 | 0.56040793 |
| 57 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.55153829 |
| 58 | Renin secretion_Homo sapiens_hsa04924 | 0.53696299 |
| 59 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.53489092 |
| 60 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.52794885 |
| 61 | Salmonella infection_Homo sapiens_hsa05132 | 0.52357499 |
| 62 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52008756 |
| 63 | Colorectal cancer_Homo sapiens_hsa05210 | 0.51740769 |
| 64 | Phagosome_Homo sapiens_hsa04145 | 0.50549544 |
| 65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.50214966 |
| 66 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.47546670 |
| 67 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.45826098 |
| 68 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.44821428 |
| 69 | Endocytosis_Homo sapiens_hsa04144 | 0.44375712 |
| 70 | Phototransduction_Homo sapiens_hsa04744 | 0.43760720 |
| 71 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.41051216 |
| 72 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.38446050 |
| 73 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.36557888 |
| 74 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.36004465 |
| 75 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.34495031 |
| 76 | Endometrial cancer_Homo sapiens_hsa05213 | 0.34431415 |
| 77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.33237792 |
| 78 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.32464231 |
| 79 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.31751879 |
| 80 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.30990888 |
| 81 | Lysosome_Homo sapiens_hsa04142 | 0.30779253 |
| 82 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.30135528 |
| 83 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29907212 |
| 84 | Shigellosis_Homo sapiens_hsa05131 | 0.26604503 |
| 85 | Other glycan degradation_Homo sapiens_hsa00511 | 0.26097877 |
| 86 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.25798025 |
| 87 | Pertussis_Homo sapiens_hsa05133 | 0.25785015 |
| 88 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.24826549 |
| 89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.20522656 |
| 90 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.20030002 |
| 91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.18961884 |
| 92 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.18091112 |
| 93 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.17679363 |
| 94 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.16888280 |
| 95 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.15610369 |
| 96 | Insulin resistance_Homo sapiens_hsa04931 | 0.15081167 |
| 97 | Salivary secretion_Homo sapiens_hsa04970 | 0.14511161 |
| 98 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.14084161 |
| 99 | Basal transcription factors_Homo sapiens_hsa03022 | 0.13807817 |
| 100 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.13449113 |

