GINM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of sequestering of triglyceride (GO:0010889)4.75623791
2valine metabolic process (GO:0006573)4.55174598
3fatty acid beta-oxidation (GO:0006635)4.31941875
4keratan sulfate catabolic process (GO:0042340)4.30213891
5branched-chain amino acid catabolic process (GO:0009083)3.95107275
6collagen fibril organization (GO:0030199)3.93925760
7fatty acid oxidation (GO:0019395)3.90021053
8lipid oxidation (GO:0034440)3.86181646
9branched-chain amino acid metabolic process (GO:0009081)3.84764434
10protein heterotrimerization (GO:0070208)3.74730440
11cell adhesion mediated by integrin (GO:0033627)3.72576609
12fatty acid catabolic process (GO:0009062)3.71380099
13signal peptide processing (GO:0006465)3.67677054
14extracellular fibril organization (GO:0043206)3.66799964
15low-density lipoprotein particle clearance (GO:0034383)3.66145324
16kidney mesenchyme development (GO:0072074)3.55685875
17regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.54873904
18virion attachment to host cell (GO:0019062)3.54557855
19adhesion of symbiont to host cell (GO:0044650)3.54557855
20sequestering of extracellular ligand from receptor (GO:0035581)3.49519936
21type B pancreatic cell proliferation (GO:0044342)3.43570148
22fatty acid transmembrane transport (GO:1902001)3.41496407
23protein retention in ER lumen (GO:0006621)3.40981313
24regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.39863960
25biotin metabolic process (GO:0006768)3.38652015
26metanephric mesenchyme development (GO:0072075)3.38300591
27fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.35008335
28brown fat cell differentiation (GO:0050873)3.28259343
29tricarboxylic acid metabolic process (GO:0072350)3.28021712
30regulation of integrin-mediated signaling pathway (GO:2001044)3.25788174
31negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.20751950
32monocarboxylic acid catabolic process (GO:0072329)3.15359309
33mesenchymal-epithelial cell signaling (GO:0060638)3.15276407
34negative regulation of macrophage derived foam cell differentiation (GO:0010745)3.14878237
35skin morphogenesis (GO:0043589)3.14159670
36positive regulation of fatty acid oxidation (GO:0046321)3.13810124
37erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.13280854
38L-phenylalanine catabolic process (GO:0006559)3.13280854
39carnitine shuttle (GO:0006853)3.11786576
40uterus development (GO:0060065)3.10449620
41carnitine metabolic process (GO:0009437)3.09817372
42transcytosis (GO:0045056)3.09291717
43positive regulation of fatty acid beta-oxidation (GO:0032000)3.06437698
44fibril organization (GO:0097435)3.04458576
45nucleotide transmembrane transport (GO:1901679)3.01515591
46sulfur amino acid catabolic process (GO:0000098)2.98030657
47L-phenylalanine metabolic process (GO:0006558)2.96853846
48erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.96853846
49xenobiotic catabolic process (GO:0042178)2.92921957
50alpha-linolenic acid metabolic process (GO:0036109)2.90835614
51endosome to pigment granule transport (GO:0043485)2.90490261
52endosome to melanosome transport (GO:0035646)2.90490261
53regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.89976380
54Golgi transport vesicle coating (GO:0048200)2.89837988
55COPI coating of Golgi vesicle (GO:0048205)2.89837988
56response to redox state (GO:0051775)2.88462468
57endodermal cell differentiation (GO:0035987)2.87901035
58triglyceride catabolic process (GO:0019433)2.86216982
59lipid storage (GO:0019915)2.85548612
60amino-acid betaine metabolic process (GO:0006577)2.83006415
61cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.82462821
62regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.82299331
63triglyceride homeostasis (GO:0070328)2.80653611
64acylglycerol homeostasis (GO:0055090)2.80653611
65cellular response to ATP (GO:0071318)2.79790856
66acetyl-CoA metabolic process (GO:0006084)2.77118519
67extracellular matrix assembly (GO:0085029)2.76844326
68positive regulation of glycolytic process (GO:0045821)2.74228962
69lysine catabolic process (GO:0006554)2.72998873
70lysine metabolic process (GO:0006553)2.72998873
71protein hydroxylation (GO:0018126)2.72192750
72glyoxylate metabolic process (GO:0046487)2.72017501
73smooth muscle tissue development (GO:0048745)2.71973870
74short-chain fatty acid metabolic process (GO:0046459)2.71146935
75COPII vesicle coating (GO:0048208)2.70761286
76regulation of triglyceride catabolic process (GO:0010896)2.69647236
77peptidyl-proline hydroxylation (GO:0019511)2.67145718
78lipid particle organization (GO:0034389)2.65461824
79tricarboxylic acid cycle (GO:0006099)2.65344229
80negative regulation of lipid storage (GO:0010888)2.65099249
81regulation of cholesterol storage (GO:0010885)2.62126067
82magnesium ion transport (GO:0015693)2.61421450
83extracellular negative regulation of signal transduction (GO:1900116)2.60769674
84extracellular regulation of signal transduction (GO:1900115)2.60769674
85peptidyl-glutamic acid carboxylation (GO:0017187)2.60574241
86protein carboxylation (GO:0018214)2.60574241
87retina vasculature morphogenesis in camera-type eye (GO:0061299)2.60274360
88acyl-CoA biosynthetic process (GO:0071616)2.59742611
89thioester biosynthetic process (GO:0035384)2.59742611
90regulation of type B pancreatic cell apoptotic process (GO:2000674)2.59641016
91regulation of fatty acid oxidation (GO:0046320)2.57991137
92middle ear morphogenesis (GO:0042474)2.57854995
93regulation of metalloenzyme activity (GO:0048552)2.57704308
94membrane budding (GO:0006900)2.57243305
95negative regulation of nitric-oxide synthase activity (GO:0051001)2.56935300
96glomerular basement membrane development (GO:0032836)2.55761889
97carnitine transmembrane transport (GO:1902603)2.55124019
98response to phenylpropanoid (GO:0080184)2.54926587
99seminiferous tubule development (GO:0072520)2.53940341
100carnitine transport (GO:0015879)2.52810486
101amino-acid betaine transport (GO:0015838)2.52810486
102UDP-N-acetylglucosamine metabolic process (GO:0006047)2.50661381
103oligosaccharide catabolic process (GO:0009313)2.50527446
104positive regulation of fatty acid metabolic process (GO:0045923)2.50102948
105cysteine metabolic process (GO:0006534)2.50099457
106plasma lipoprotein particle clearance (GO:0034381)2.49811588
107intracellular lipid transport (GO:0032365)2.49262692
108complement activation, alternative pathway (GO:0006957)2.47879218
109collagen metabolic process (GO:0032963)2.47641452
110acylglycerol catabolic process (GO:0046464)2.47005773
111neutral lipid catabolic process (GO:0046461)2.47005773
112hindbrain development (GO:0030902)2.46655432
113exocrine pancreas development (GO:0031017)2.45710560
114cellular response to vitamin D (GO:0071305)2.45347351
115aromatic amino acid family catabolic process (GO:0009074)2.45124859
116collagen catabolic process (GO:0030574)2.43448744
117white fat cell differentiation (GO:0050872)2.43206911
118polyketide metabolic process (GO:0030638)2.42035942
119doxorubicin metabolic process (GO:0044598)2.42035942
120daunorubicin metabolic process (GO:0044597)2.42035942
121regulation of cholesterol metabolic process (GO:0090181)2.41820863
1222-oxoglutarate metabolic process (GO:0006103)2.40987350
123heart contraction (GO:0060047)2.40318499
124heart process (GO:0003015)2.40318499
125negative regulation of protein autophosphorylation (GO:0031953)2.39794854
126maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.39096823
127organic acid catabolic process (GO:0016054)2.38111571
128carboxylic acid catabolic process (GO:0046395)2.38111571
129vascular endothelial growth factor signaling pathway (GO:0038084)2.37917986
130endocardial cushion development (GO:0003197)2.35562809
131peptide catabolic process (GO:0043171)2.34893514
132cellular response to vitamin (GO:0071295)2.34820794
133fatty-acyl-CoA biosynthetic process (GO:0046949)2.34684961
134response to copper ion (GO:0046688)2.34190700
135negative regulation of smooth muscle cell migration (GO:0014912)2.33478088
136tooth mineralization (GO:0034505)2.33223074
137cellular lipid catabolic process (GO:0044242)2.32729982
138negative regulation of fatty acid biosynthetic process (GO:0045717)2.32586727
139thioester metabolic process (GO:0035383)2.32561670
140acyl-CoA metabolic process (GO:0006637)2.32561670
141triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.31906257
142regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.31895561
143metanephric tubule development (GO:0072170)2.31708697
144metanephric nephron tubule development (GO:0072234)2.31708697
145positive regulation of cartilage development (GO:0061036)2.31503528
146localization within membrane (GO:0051668)2.31418098
147positive regulation of lipid storage (GO:0010884)2.31067891
148adhesion of symbiont to host (GO:0044406)2.30959141
149bile acid biosynthetic process (GO:0006699)2.29168901
150purine ribonucleotide transport (GO:0015868)2.28762190
151negative regulation of nitric oxide biosynthetic process (GO:0045019)2.28599191
152lung vasculature development (GO:0060426)2.28466268
153regulation of plasminogen activation (GO:0010755)2.28334502
154metanephric nephron epithelium development (GO:0072243)2.28079116
155positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.27318002
156phagocytosis, recognition (GO:0006910)2.26948515
157homocysteine metabolic process (GO:0050667)2.26272749
158positive regulation of lipid catabolic process (GO:0050996)2.26044495
159regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.25511531
160multicellular organismal catabolic process (GO:0044243)2.25217939
161positive regulation of mitochondrial fission (GO:0090141)2.24890704
162L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.24818956
163muscle cell migration (GO:0014812)2.24369371
164regulation of triglyceride metabolic process (GO:0090207)2.23965682
165cell migration involved in heart development (GO:0060973)2.23745983
166polyol transport (GO:0015791)2.23054881
167multicellular organismal macromolecule metabolic process (GO:0044259)2.22115839
168acylglycerol biosynthetic process (GO:0046463)2.21606450
169neutral lipid biosynthetic process (GO:0046460)2.21606450
170tyrosine metabolic process (GO:0006570)2.21549994
171positive regulation of smooth muscle cell migration (GO:0014911)2.21446631
172aminoglycoside antibiotic metabolic process (GO:0030647)2.21362613
173mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.20843574
174triglyceride biosynthetic process (GO:0019432)2.20757577
175multicellular organismal metabolic process (GO:0044236)2.20751738
176fatty-acyl-CoA metabolic process (GO:0035337)2.20552512
177platelet dense granule organization (GO:0060155)2.17222337
178protein maturation by protein folding (GO:0022417)2.16816628
179wound healing, spreading of epidermal cells (GO:0035313)2.16365059
180lipopolysaccharide biosynthetic process (GO:0009103)2.15925315
181pattern specification involved in kidney development (GO:0061004)2.15321110
182regulation of phospholipase A2 activity (GO:0032429)2.14087007
183lymphangiogenesis (GO:0001946)2.12901987
184tonic smooth muscle contraction (GO:0014820)2.12768338
1854-hydroxyproline metabolic process (GO:0019471)2.12356828
186metanephric epithelium development (GO:0072207)2.10876093
187extracellular matrix disassembly (GO:0022617)2.09950176
188response to hyperoxia (GO:0055093)2.09625372
189response to increased oxygen levels (GO:0036296)2.09625372
190L-methionine biosynthetic process (GO:0071265)2.09360913
191amino acid salvage (GO:0043102)2.09360913

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.11324003
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.40927883
3TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.04252597
4RXR_22158963_ChIP-Seq_LIVER_Mouse4.01329716
5LXR_22158963_ChIP-Seq_LIVER_Mouse3.49049617
6EGR1_23403033_ChIP-Seq_LIVER_Mouse3.46486658
7PPARA_22158963_ChIP-Seq_LIVER_Mouse3.42331589
8CLOCK_20551151_ChIP-Seq_293T_Human3.11978412
9TP63_17297297_ChIP-ChIP_HaCaT_Human2.95619317
10CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.87492515
11TRIM28_21343339_ChIP-Seq_HEK293_Human2.87309016
12GATA1_22025678_ChIP-Seq_K562_Human2.87252186
13FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.71702034
14IRF8_22096565_ChIP-ChIP_GC-B_Human2.59817676
15STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.53093306
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.20631606
17RARG_19884340_ChIP-ChIP_MEFs_Mouse2.15504057
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.09789332
19PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.09457008
20BRD4_25478319_ChIP-Seq_HGPS_Human2.06187318
21NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.02818862
22ESR1_21235772_ChIP-Seq_MCF-7_Human1.98100547
23CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.90325387
24EED_16625203_ChIP-ChIP_MESCs_Mouse1.83582655
25ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79411480
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.78806034
27TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.78777475
28NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.76935295
29NRF2_20460467_ChIP-Seq_MEFs_Mouse1.76935295
30HIF1A_21447827_ChIP-Seq_MCF-7_Human1.71254988
31CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.64313374
32CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.62638630
33CJUN_26792858_Chip-Seq_BT549_Human1.61545020
34HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.60890922
35SOX2_20726797_ChIP-Seq_SW620_Human1.57636572
36FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.54786454
37SMAD_19615063_ChIP-ChIP_OVARY_Human1.50541194
38SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.50094930
39TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.48041787
40ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.47472998
41PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.45979925
42GBX2_23144817_ChIP-Seq_PC3_Human1.45949930
43GATA2_21666600_ChIP-Seq_HMVEC_Human1.44918063
44EP300_21415370_ChIP-Seq_HL-1_Mouse1.42260754
45CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.41814987
46SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40896809
47BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.39722690
48AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36499026
49PPAR_26484153_Chip-Seq_NCI-H1993_Human1.36025261
50SALL4_18804426_ChIP-ChIP_XEN_Mouse1.33947817
51CDX2_19796622_ChIP-Seq_MESCs_Mouse1.32902476
52RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.32089142
53SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.31620816
54IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.31557325
55PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.28006498
56SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.26792606
57Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.26367435
58SRF_21415370_ChIP-Seq_HL-1_Mouse1.26212527
59KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.25298713
60TP53_16413492_ChIP-PET_HCT116_Human1.23802423
61ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.23677958
62TBX20_22080862_ChIP-Seq_HEART_Mouse1.22303525
63TBX20_22328084_ChIP-Seq_HEART_Mouse1.22303525
64PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21632637
65BP1_19119308_ChIP-ChIP_Hs578T_Human1.21111270
66WT1_19549856_ChIP-ChIP_CCG9911_Human1.20065659
67TAF15_26573619_Chip-Seq_HEK293_Human1.19757740
68EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18565427
69SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.15683355
70EZH2_27294783_Chip-Seq_NPCs_Mouse1.14696492
71BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.14317617
72P300_19829295_ChIP-Seq_ESCs_Human1.11616843
73GATA4_25053715_ChIP-Seq_YYC3_Human1.11275625
74RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.10105889
75TP53_20018659_ChIP-ChIP_R1E_Mouse1.09869230
76CDX2_22108803_ChIP-Seq_LS180_Human1.08931250
77OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08556422
78ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.08354720
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.07719237
80VDR_22108803_ChIP-Seq_LS180_Human1.07559386
81SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.07037013
82NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06537226
83ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05117541
84ELF1_17652178_ChIP-ChIP_JURKAT_Human1.04831151
85SMAD4_21799915_ChIP-Seq_A2780_Human1.04341608
86CRX_20693478_ChIP-Seq_RETINA_Mouse1.03401273
87P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02959970
88SA1_22415368_ChIP-Seq_MEFs_Mouse1.02730825
89SOX2_27498859_Chip-Seq_STOMACH_Mouse1.02543386
90PIAS1_25552417_ChIP-Seq_VCAP_Human1.02446991
91PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00396443
92PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99797574
93AR_25329375_ChIP-Seq_VCAP_Human0.99658630
94AR_20517297_ChIP-Seq_VCAP_Human0.99546833
95NFI_21473784_ChIP-Seq_ESCs_Mouse0.99213631
96STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.99022923
97EZH2_18974828_ChIP-Seq_MESCs_Mouse0.98020866
98RNF2_18974828_ChIP-Seq_MESCs_Mouse0.98020866
99RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.96994724
100FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.96761067
101NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.95068429
102SUZ12_27294783_Chip-Seq_NPCs_Mouse0.93910797
103NR3C1_23031785_ChIP-Seq_PC12_Mouse0.92363288
104TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92034283
105MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.91971455
106AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.91752072
107CBX2_27304074_Chip-Seq_ESCs_Mouse0.91095819
108NANOG_18555785_Chip-Seq_ESCs_Mouse0.90873146
109GATA3_24758297_ChIP-Seq_MCF-7_Human0.89818764
110TOP2B_26459242_ChIP-Seq_MCF-7_Human0.89808251
111ELK1_22589737_ChIP-Seq_MCF10A_Human0.88874957
112P53_22387025_ChIP-Seq_ESCs_Mouse0.88871798
113MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88454674
114CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.88315088
115PPARD_21283829_ChIP-Seq_MYOFIBROBLAST_Human0.88103513
116CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88023599
117CBP_21632823_ChIP-Seq_H3396_Human0.87231518
118GABP_17652178_ChIP-ChIP_JURKAT_Human0.86171126
119TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85605207
120SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.85417404
121MTF2_20144788_ChIP-Seq_MESCs_Mouse0.84324648
122UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84249487
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.84006779
124IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.81840221
125TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.81667555
126EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.81406973
127FOXO3_23340844_ChIP-Seq_DLD1_Human0.81359449
128ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81263084
129ESR2_21235772_ChIP-Seq_MCF-7_Human0.80990958
130BCAT_22108803_ChIP-Seq_LS180_Human0.80758461
131POU3F2_20337985_ChIP-ChIP_501MEL_Human0.80096361
132PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.79394029
133SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.79182172
134SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.79182172
135FOXA1_25552417_ChIP-Seq_VCAP_Human0.78165487
136GATA4_21415370_ChIP-Seq_HL-1_Mouse0.77713827
137ESR1_20079471_ChIP-ChIP_T-47D_Human0.76439889
138HTT_18923047_ChIP-ChIP_STHdh_Human0.75950348
139NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.75278850
140ELK1_19687146_ChIP-ChIP_HELA_Human0.74735559
141JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.73836215
142PCGF2_27294783_Chip-Seq_NPCs_Mouse0.72496584
143GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.72220405
144FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.71773842
145TP53_18474530_ChIP-ChIP_U2OS_Human0.70686730
146SOX9_24532713_ChIP-Seq_HFSC_Mouse0.70470131
147FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.68952282
148VDR_24787735_ChIP-Seq_THP-1_Human0.68386695
149TP63_23658742_ChIP-Seq_EP156T_Human0.68109334
150JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.67990636
151PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.66697500
152CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.65570170
153NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.64823144

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005670_abnormal_white_adipose4.10685438
2MP0008438_abnormal_cutaneous_collagen3.10562593
3MP0002139_abnormal_hepatobiliary_system3.01670634
4MP0005360_urolithiasis3.00235461
5MP0003195_calcinosis2.80492795
6MP0000013_abnormal_adipose_tissue2.52532049
7MP0003724_increased_susceptibility_to2.51468277
8MP0002837_dystrophic_cardiac_calcinosis2.42632127
9MP0005365_abnormal_bile_salt2.42316462
10MP0005666_abnormal_adipose_tissue2.23891168
11MP0004130_abnormal_muscle_cell2.23797493
12MP0005257_abnormal_intraocular_pressure2.18253206
13MP0003191_abnormal_cellular_cholesterol2.05913686
14MP0005623_abnormal_meninges_morphology2.03231886
15MP0005275_abnormal_skin_tensile2.02975674
16MP0003186_abnormal_redox_activity2.01927667
17MP0004272_abnormal_basement_membrane2.00864451
18MP0010329_abnormal_lipoprotein_level1.95348482
19MP0003011_delayed_dark_adaptation1.91155447
20MP0002971_abnormal_brown_adipose1.85753549
21MP0005085_abnormal_gallbladder_physiolo1.80624891
22MP0009780_abnormal_chondrocyte_physiolo1.76891461
23MP0005375_adipose_tissue_phenotype1.75674612
24MP0005332_abnormal_amino_acid1.73358155
25MP0001661_extended_life_span1.66739479
26MP0002138_abnormal_hepatobiliary_system1.66691015
27MP0009643_abnormal_urine_homeostasis1.66530803
28MP0001879_abnormal_lymphatic_vessel1.66093528
29MP0003252_abnormal_bile_duct1.60064068
30MP0002876_abnormal_thyroid_physiology1.59587012
31MP0008875_abnormal_xenobiotic_pharmacok1.52304382
32MP0003279_aneurysm1.50010725
33MP0002118_abnormal_lipid_homeostasis1.49878159
34MP0000003_abnormal_adipose_tissue1.49865675
35MP0004185_abnormal_adipocyte_glucose1.49698388
36MP0005503_abnormal_tendon_morphology1.49006907
37MP0003283_abnormal_digestive_organ1.45896879
38MP0001299_abnormal_eye_distance/1.45097244
39MP0004043_abnormal_pH_regulation1.41492202
40MP0003806_abnormal_nucleotide_metabolis1.40881481
41MP0005084_abnormal_gallbladder_morpholo1.40853012
42MP0003868_abnormal_feces_composition1.37280411
43MP0004145_abnormal_muscle_electrophysio1.36184113
44MP0003941_abnormal_skin_development1.35609010
45MP0010386_abnormal_urinary_bladder1.34972101
46MP0010368_abnormal_lymphatic_system1.34567296
47MP0000751_myopathy1.30791614
48MP0005334_abnormal_fat_pad1.30749441
49MP0008775_abnormal_heart_ventricle1.30670808
50MP0004019_abnormal_vitamin_homeostasis1.30390425
51MP0005187_abnormal_penis_morphology1.26755119
52MP0003705_abnormal_hypodermis_morpholog1.26672251
53MP0001666_abnormal_nutrient_absorption1.24946589
54MP0006036_abnormal_mitochondrial_physio1.23800709
55MP0009384_cardiac_valve_regurgitation1.23097077
56MP0001764_abnormal_homeostasis1.23058925
57MP0001853_heart_inflammation1.22227052
58MP0001756_abnormal_urination1.22215257
59MP0005535_abnormal_body_temperature1.18384277
60MP0000767_abnormal_smooth_muscle1.18130090
61MP0002254_reproductive_system_inflammat1.17920279
62MP0002078_abnormal_glucose_homeostasis1.16751770
63MP0009115_abnormal_fat_cell1.16499270
64MP0005319_abnormal_enzyme/_coenzyme1.16206116
65MP0001958_emphysema1.14646538
66MP0009250_abnormal_appendicular_skeleto1.14545853
67MP0004510_myositis1.14342582
68MP0000609_abnormal_liver_physiology1.14195730
69MP0003950_abnormal_plasma_membrane1.12738291
70MP0002877_abnormal_melanocyte_morpholog1.11565820
71MP0003942_abnormal_urinary_system1.11248867
72MP0003828_pulmonary_edema1.11046603
73MP0000538_abnormal_urinary_bladder1.10411277
74MP0005379_endocrine/exocrine_gland_phen1.09456522
75MP0002295_abnormal_pulmonary_circulatio1.07656916
76MP0000343_altered_response_to1.06318284
77MP0000230_abnormal_systemic_arterial1.05422144
78MP0001243_abnormal_dermal_layer1.02588793
79MP0005595_abnormal_vascular_smooth1.02456065
80MP0002060_abnormal_skin_morphology1.02337695
81MP0005023_abnormal_wound_healing1.02080616
82MP0006054_spinal_hemorrhage1.00212168
83MP0005220_abnormal_exocrine_pancreas0.99580072
84MP0005636_abnormal_mineral_homeostasis0.98175851
85MP0001542_abnormal_bone_strength0.97516644
86MP0009764_decreased_sensitivity_to0.96548629
87MP0000163_abnormal_cartilage_morphology0.96004946
88MP0005164_abnormal_response_to0.94692639
89MP0000749_muscle_degeneration0.94197322
90MP0005058_abnormal_lysosome_morphology0.94059492
91MP0005330_cardiomyopathy0.93075404
92MP0003183_abnormal_peptide_metabolism0.91909431
93MP0002693_abnormal_pancreas_physiology0.90940264
94MP0000566_synostosis0.90515338
95MP0003122_maternal_imprinting0.90488911
96MP0005584_abnormal_enzyme/coenzyme_acti0.89937798
97MP0002896_abnormal_bone_mineralization0.89858602
98MP0002638_abnormal_pupillary_reflex0.89721983
99MP0001944_abnormal_pancreas_morphology0.89308998
100MP0003959_abnormal_lean_body0.89122298
101MP0001533_abnormal_skeleton_physiology0.88830367
102MP0006138_congestive_heart_failure0.88545178
103MP0002970_abnormal_white_adipose0.88178399
104MP0002168_other_aberrant_phenotype0.87585675
105MP0001881_abnormal_mammary_gland0.87320928
106MP0000750_abnormal_muscle_regeneration0.86778760
107MP0004782_abnormal_surfactant_physiolog0.84081775
108MP0002972_abnormal_cardiac_muscle0.83013126
109MP0003091_abnormal_cell_migration0.81772543
110MP0001544_abnormal_cardiovascular_syste0.81596745
111MP0005385_cardiovascular_system_phenoty0.81596745
112MP0005508_abnormal_skeleton_morphology0.81117934
113MP0005165_increased_susceptibility_to0.80248146
114MP0005620_abnormal_muscle_contractility0.79725181
115MP0003566_abnormal_cell_adhesion0.79046223
116MP0002136_abnormal_kidney_physiology0.77612745
117MP0005369_muscle_phenotype0.76795804
118MP0004084_abnormal_cardiac_muscle0.76341171
119MP0000534_abnormal_ureter_morphology0.75834385
120MP0003646_muscle_fatigue0.75611769
121MP0005390_skeleton_phenotype0.75521300
122MP0002108_abnormal_muscle_morphology0.75481926
123MP0004215_abnormal_myocardial_fiber0.75271050
124MP0003690_abnormal_glial_cell0.74704238
125MP0004036_abnormal_muscle_relaxation0.74101185
126MP0001986_abnormal_taste_sensitivity0.74022590
127MP0002115_abnormal_skeleton_extremities0.71970258
128MP0000747_muscle_weakness0.70248094
129MP0003172_abnormal_lysosome_physiology0.69615649
130MP0002234_abnormal_pharynx_morphology0.69574793
131MP0002135_abnormal_kidney_morphology0.69329063
132MP0002090_abnormal_vision0.69110740
133MP0003300_gastrointestinal_ulcer0.68573814
134MP0000049_abnormal_middle_ear0.68116706
135MP0000762_abnormal_tongue_morphology0.67546206
136MP0002106_abnormal_muscle_physiology0.66815448
137MP0002163_abnormal_gland_morphology0.65334674
138MP0004484_altered_response_of0.65042550
139MP0002128_abnormal_blood_circulation0.64488699
140MP0010030_abnormal_orbit_morphology0.60885043
141MP0002160_abnormal_reproductive_system0.59566017
142MP0009840_abnormal_foam_cell0.59130349
143MP0004087_abnormal_muscle_fiber0.58142231
144MP0000428_abnormal_craniofacial_morphol0.57986897
145MP0006072_abnormal_retinal_apoptosis0.57979392

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.89748873
2Hypoglycemic coma (HP:0001325)5.55888717
3Protrusio acetabuli (HP:0003179)5.32596013
4Generalized aminoaciduria (HP:0002909)4.15620554
5Soft skin (HP:0000977)4.07574758
6Abnormality of fatty-acid metabolism (HP:0004359)3.92112259
7Vascular tortuosity (HP:0004948)3.85549681
8Hyperglycinuria (HP:0003108)3.84642964
9Ketoacidosis (HP:0001993)3.80501267
10Aortic dissection (HP:0002647)3.74837860
11Hypoglycemic seizures (HP:0002173)3.61864462
12Proximal tubulopathy (HP:0000114)3.56616385
13Type 1 muscle fiber predominance (HP:0003803)3.53184217
14Insulin-resistant diabetes mellitus (HP:0000831)3.51732298
15Follicular hyperkeratosis (HP:0007502)3.51552841
16Hyperinsulinemic hypoglycemia (HP:0000825)3.50414989
17Ankle contracture (HP:0006466)3.41888445
18Symptomatic seizures (HP:0011145)3.37990223
19Cardiovascular calcification (HP:0011915)3.23235832
20Ketosis (HP:0001946)3.20955637
21Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.19891915
22Abnormality of dicarboxylic acid metabolism (HP:0010995)3.16772017
23Dicarboxylic aciduria (HP:0003215)3.16772017
24Arterial tortuosity (HP:0005116)3.15054806
25Atrophic scars (HP:0001075)3.08175167
26Aortic aneurysm (HP:0004942)3.07871609
27Hyperglycemia (HP:0003074)3.02818963
28Myoglobinuria (HP:0002913)3.01120299
29Hepatic necrosis (HP:0002605)2.99877880
30Abnormality of glycine metabolism (HP:0010895)2.98882589
31Abnormality of serine family amino acid metabolism (HP:0010894)2.98882589
32Abnormality of aromatic amino acid family metabolism (HP:0004338)2.97299147
33Abnormality of dentin (HP:0010299)2.95585734
34Bladder diverticulum (HP:0000015)2.90595803
35Vertebral compression fractures (HP:0002953)2.86599220
36Cervical subluxation (HP:0003308)2.85739569
37Facial diplegia (HP:0001349)2.82195677
38Wormian bones (HP:0002645)2.80944260
39Metaphyseal dysplasia (HP:0100255)2.80539944
40Infantile muscular hypotonia (HP:0008947)2.79353326
41Oligomenorrhea (HP:0000876)2.78011709
42Abnormality of the intrinsic pathway (HP:0010989)2.77811958
43Neonatal short-limb short stature (HP:0008921)2.76639890
44Vascular calcification (HP:0004934)2.76431394
45Hypoalphalipoproteinemia (HP:0003233)2.75659360
46Xanthomatosis (HP:0000991)2.74145767
47Nausea (HP:0002018)2.73481596
48Renal cortical cysts (HP:0000803)2.72657568
49Hydroxyprolinuria (HP:0003080)2.70173123
50Abnormality of proline metabolism (HP:0010907)2.70173123
51Increased serum pyruvate (HP:0003542)2.59571635
52Adrenal hypoplasia (HP:0000835)2.58159310
53Hypertriglyceridemia (HP:0002155)2.56268999
54Asymmetric septal hypertrophy (HP:0001670)2.54763309
55Insulin resistance (HP:0000855)2.54684528
56Urinary glycosaminoglycan excretion (HP:0003541)2.53337333
57Hyperlipoproteinemia (HP:0010980)2.51795393
58Prolonged partial thromboplastin time (HP:0003645)2.50478285
59Abnormality of glycolipid metabolism (HP:0010969)2.50134177
60Abnormality of liposaccharide metabolism (HP:0010968)2.50134177
61Abnormality of glycosphingolipid metabolism (HP:0004343)2.50134177
62Dysostosis multiplex (HP:0000943)2.46555090
63Abnormality of urine glucose concentration (HP:0011016)2.44842158
64Glycosuria (HP:0003076)2.44842158
65Rhabdomyolysis (HP:0003201)2.44124613
66Abnormality of purine metabolism (HP:0004352)2.43336534
67Peritonitis (HP:0002586)2.42565112
68Acanthosis nigricans (HP:0000956)2.41236865
69Hyperammonemia (HP:0001987)2.40569590
70Slender build (HP:0001533)2.40434256
71Abnormality of mucopolysaccharide metabolism (HP:0011020)2.39586028
72Abnormality of polysaccharide metabolism (HP:0011012)2.39586028
73Abnormality of glycosaminoglycan metabolism (HP:0004371)2.39586028
74Spondylolisthesis (HP:0003302)2.38898105
75Ovoid vertebral bodies (HP:0003300)2.33965550
76Abnormality of glutamine family amino acid metabolism (HP:0010902)2.33687314
77Complement deficiency (HP:0004431)2.32122330
78Increased muscle lipid content (HP:0009058)2.28986080
79Ulnar deviation of the wrist (HP:0003049)2.28918941
80Mitral stenosis (HP:0001718)2.27982804
81Cerebral edema (HP:0002181)2.26089778
82Acute encephalopathy (HP:0006846)2.24828099
83Vacuolated lymphocytes (HP:0001922)2.23256133
84Intrahepatic cholestasis (HP:0001406)2.19768025
85Bone cyst (HP:0012062)2.19524355
86Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.18880150
87Lethargy (HP:0001254)2.15747290
88Decreased activity of mitochondrial respiratory chain (HP:0008972)2.13385490
89Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.13385490
90Abnormal hemoglobin (HP:0011902)2.13235732
91Abnormality of the common coagulation pathway (HP:0010990)2.13126925
92Pancreatitis (HP:0001733)2.10025398
93Increased corneal curvature (HP:0100692)2.09979019
94Keratoconus (HP:0000563)2.09979019
95Joint stiffness (HP:0001387)2.08312209
96Blue sclerae (HP:0000592)2.07795534
97Broad metatarsal (HP:0001783)2.06540602
98Pancreatic islet-cell hyperplasia (HP:0004510)2.05167399
99Pulmonary artery stenosis (HP:0004415)2.04625652
100Myotonia (HP:0002486)2.03726977
101Hyperglycinemia (HP:0002154)2.03257628
102Genu recurvatum (HP:0002816)2.02727717
103Gout (HP:0001997)2.02550199
104Hypolipoproteinemia (HP:0010981)2.01866938
105Acute necrotizing encephalopathy (HP:0006965)2.01601594
106Increased purine levels (HP:0004368)2.00615733
107Hyperuricemia (HP:0002149)2.00615733
108Metabolic acidosis (HP:0001942)2.00177826
109Tetraparesis (HP:0002273)1.99425153
110Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.99212443
111Abnormal cartilage morphology (HP:0002763)1.97039084
112Abnormality of glycolysis (HP:0004366)1.95342271
113Pigmentary retinal degeneration (HP:0001146)1.94948919
114Abnormal mitochondria in muscle tissue (HP:0008316)1.93974647
115Vomiting (HP:0002013)1.93480419
116Fragile skin (HP:0001030)1.92831145
117Dilatation of the ascending aorta (HP:0005111)1.92604850
118Absent frontal sinuses (HP:0002688)1.92324313
119Abnormal delivery (HP:0001787)1.91226292
120Large for gestational age (HP:0001520)1.90588584
121Overgrowth (HP:0001548)1.90179765
122Beaking of vertebral bodies (HP:0004568)1.89726722
123Redundant skin (HP:0001582)1.89078733
124Hyperextensible skin (HP:0000974)1.87766084
125Toxemia of pregnancy (HP:0100603)1.87341213
126Abnormality of the acetabulum (HP:0003170)1.84220871
127Hepatocellular necrosis (HP:0001404)1.84041383
128Epidermoid cyst (HP:0200040)1.84039881
129Mildly elevated creatine phosphokinase (HP:0008180)1.83340224
130Skin nodule (HP:0200036)1.83191522
131Delayed gross motor development (HP:0002194)1.81505525
132Lipoatrophy (HP:0100578)1.81270060
133Lipid accumulation in hepatocytes (HP:0006561)1.81125749
134Joint hemorrhage (HP:0005261)1.80145749
135Entropion (HP:0000621)1.79995143
136Lactic acidosis (HP:0003128)1.79653872
137Aortic valve stenosis (HP:0001650)1.79631646
138Irregular vertebral endplates (HP:0003301)1.78500594
139Exertional dyspnea (HP:0002875)1.78345784
140Prenatal maternal abnormality (HP:0002686)1.78166297
141Myocardial infarction (HP:0001658)1.77764266
142Hypercholesterolemia (HP:0003124)1.77530988
143Respiratory distress (HP:0002098)1.77371445
144Patent foramen ovale (HP:0001655)1.76972690
145Breech presentation (HP:0001623)1.76895785
146Tibial bowing (HP:0002982)1.76255412
147Late onset (HP:0003584)1.76076950
148Fat malabsorption (HP:0002630)1.75693463
149Enlarged kidneys (HP:0000105)1.74475739
150Short nail (HP:0001799)1.74457431
151Mitochondrial inheritance (HP:0001427)1.73423501
152Conjugated hyperbilirubinemia (HP:0002908)1.73003805
153Abnormality of the ischium (HP:0003174)1.71642747
154Enlarged penis (HP:0000040)1.71523109
155Progressive neurologic deterioration (HP:0002344)1.70538354
156Reduced subcutaneous adipose tissue (HP:0003758)1.70370677
157Systemic lupus erythematosus (HP:0002725)1.70079191
158Aortic regurgitation (HP:0001659)1.70068201
159Hematochezia (HP:0002573)1.69459943
160Osteopenia (HP:0000938)1.69356208
161Abnormality of the frontal sinuses (HP:0002687)1.69281435
162Protuberant abdomen (HP:0001538)1.69224252
163Hypokalemia (HP:0002900)1.69088078
164Medial flaring of the eyebrow (HP:0010747)1.67776697
165Glucose intolerance (HP:0000833)1.67684204
166Wide anterior fontanel (HP:0000260)1.66695776
167Increased variability in muscle fiber diameter (HP:0003557)1.66668510
168Methylmalonic aciduria (HP:0012120)1.66102005
169Hemorrhage of the eye (HP:0011885)1.65929981
170Spinal rigidity (HP:0003306)1.65617157
171Tongue fasciculations (HP:0001308)1.65523123
172Osteoarthritis (HP:0002758)1.65443098
173Muscle hypertrophy of the lower extremities (HP:0008968)1.65232209
174Abnormality of nucleobase metabolism (HP:0010932)1.65117239
175Palpitations (HP:0001962)1.64754202
176Deep venous thrombosis (HP:0002625)1.64488656
177Hypokalemic alkalosis (HP:0001949)1.64072157
178Renal Fanconi syndrome (HP:0001994)1.63753720
179Mitral regurgitation (HP:0001653)1.63604171
180Abnormality of complement system (HP:0005339)1.62977015
181Long toe (HP:0010511)1.62450145
182Mucopolysacchariduria (HP:0008155)1.61955759
183Bradycardia (HP:0001662)1.60544284
184Abnormality of alanine metabolism (HP:0010916)1.59050960
185Hyperalaninemia (HP:0003348)1.59050960
186Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.59050960
187Joint laxity (HP:0001388)1.59037531
188Biconcave vertebral bodies (HP:0004586)1.58905698
189Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.56559637
190Hypoplasia of the odontoid process (HP:0003311)1.55544160
191Femoral bowing (HP:0002980)1.55075562
192Abnormality of the calf musculature (HP:0001430)1.54190642
193Nemaline bodies (HP:0003798)1.53841925

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.17137657
2BCKDK3.82989233
3INSRR3.69455974
4IRAK33.24079593
5CASK2.94856541
6TIE12.89087838
7LIMK12.65782810
8TESK12.60458849
9ERN12.57063368
10IRAK12.23301923
11SIK12.09532044
12MAP3K122.08516949
13EPHA32.08254420
14MAPK151.98559777
15ZAK1.93240844
16FRK1.86746739
17MYLK1.82874399
18PIK3CG1.73087289
19MST41.71224263
20MOS1.68747128
21PDK21.67353947
22DMPK1.67285267
23MAP3K31.65021302
24FGFR41.58399776
25NEK91.52989240
26MAP3K141.51134401
27PDK31.50448000
28PDK41.50448000
29STK38L1.49658290
30OBSCN1.47784198
31IRAK41.46076089
32KDR1.44156550
33ILK1.42243822
34MST1R1.41391647
35FLT31.40199445
36TGFBR21.38735542
37ADRBK21.38459219
38PIK3CA1.37491403
39TAOK21.36792551
40ARAF1.33801276
41PLK21.30283620
42WNK41.28471801
43NUAK11.27696578
44FGFR31.27621006
45WNK31.24333508
46IRAK21.18589466
47EPHB21.18013883
48MET1.16037477
49NLK1.15872230
50TBK11.15844409
51PTK21.15774089
52TEC1.10259290
53EPHB11.09097421
54IKBKE1.03758367
55BMPR21.02776117
56LATS11.00934186
57TAOK31.00875397
58TTN1.00781119
59CAMK2D1.00405859
60EPHA20.99115973
61JAK10.98637497
62NEK60.98595939
63FER0.97040848
64AKT30.96342421
65PRKAA20.95059886
66CAMK1D0.93833698
67PBK0.91641887
68BMPR1B0.87667318
69TRPM70.87503231
70PAK20.85403628
71TRIB30.84481717
72PNCK0.84106182
73NTRK10.83414215
74MAPKAPK30.82728384
75DAPK30.81048964
76TYK20.80984977
77TGFBR10.80732028
78STK380.80372318
79PDGFRA0.79532349
80PRKCE0.77028419
81MAP2K30.77008967
82GRK70.76174438
83ROCK20.76125498
84PLK40.75724656
85NME20.75198208
86ROCK10.74885472
87IKBKB0.74535996
88CAMK2G0.74039467
89PINK10.73038817
90TLK10.72523709
91JAK30.72290820
92EIF2AK30.72114805
93MAPK70.69105391
94ERBB30.66963794
95MARK10.66556855
96ABL20.66205064
97MAP4K20.65515880
98CHUK0.65318672
99IGF1R0.64507211
100ADRBK10.63998839
101BCR0.62816906
102EIF2AK20.61281785
103STK240.60481589
104RPS6KA40.57634791
105GRK10.56719641
106GSK3A0.55122979
107PAK30.54875809
108TRIM280.53446028
109ERBB40.52005973
110PRKD20.51192393
111TXK0.49364164
112PHKG10.49247372
113PHKG20.49247372
114KIT0.48676304
115PRKG10.47756766
116HIPK20.46373592
117JAK20.44860712
118ABL10.43667886
119RPS6KA20.42855875
120PRKD10.42470343
121PTK60.41891886
122MAP3K130.41141091
123MAPK120.39987734
124RPS6KA50.39710375
125MAP2K10.39658548
126PTK2B0.38763986
127ZAP700.38675866
128CAMK2A0.36898464
129LMTK20.36226498
130PRKAA10.35141688
131PRKG20.34304358
132DYRK1B0.34186919
133PIM20.33834358
134MUSK0.33556721
135DDR20.33514274
136PKN10.33469285
137PDGFRB0.33276460
138STK30.33079038
139PRKACG0.32471201
140PRKD30.31919664
141CSNK1G20.30917170
142MAP3K50.30911699
143INSR0.30498468

Predicted pathways (KEGG)

RankGene SetZ-score
1Propanoate metabolism_Homo sapiens_hsa006403.30456757
2Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.24229667
3Sulfur metabolism_Homo sapiens_hsa009203.21383638
4Fatty acid degradation_Homo sapiens_hsa000713.05447023
5Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.80762344
6Maturity onset diabetes of the young_Homo sapiens_hsa049502.71412400
7Protein export_Homo sapiens_hsa030602.65505625
8Fatty acid metabolism_Homo sapiens_hsa012122.58119389
9PPAR signaling pathway_Homo sapiens_hsa033202.50728454
10Peroxisome_Homo sapiens_hsa041462.23540981
11Tryptophan metabolism_Homo sapiens_hsa003802.02845496
12Fatty acid elongation_Homo sapiens_hsa000622.02814907
13Primary bile acid biosynthesis_Homo sapiens_hsa001201.96448544
14Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.89072388
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.72091611
16Pentose and glucuronate interconversions_Homo sapiens_hsa000401.69546017
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.68916282
18Butanoate metabolism_Homo sapiens_hsa006501.67373907
19beta-Alanine metabolism_Homo sapiens_hsa004101.64605853
20Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.64109568
21Pyruvate metabolism_Homo sapiens_hsa006201.62517905
22Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.58767173
23Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.58723882
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.48044920
25Folate biosynthesis_Homo sapiens_hsa007901.42768255
26Complement and coagulation cascades_Homo sapiens_hsa046101.41480328
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.40174070
28Phenylalanine metabolism_Homo sapiens_hsa003601.39569645
29Tyrosine metabolism_Homo sapiens_hsa003501.38206609
30Starch and sucrose metabolism_Homo sapiens_hsa005001.37572369
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.37407730
32Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.33675179
33Oxidative phosphorylation_Homo sapiens_hsa001901.33541302
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.31774951
35Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.31652623
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.28481853
37Selenocompound metabolism_Homo sapiens_hsa004501.27419879
38Focal adhesion_Homo sapiens_hsa045101.24408083
39Dilated cardiomyopathy_Homo sapiens_hsa054141.23324113
40Histidine metabolism_Homo sapiens_hsa003401.21768702
41Carbon metabolism_Homo sapiens_hsa012001.19886934
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.19771136
43Chemical carcinogenesis_Homo sapiens_hsa052041.16708090
44Fatty acid biosynthesis_Homo sapiens_hsa000611.14618809
45Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.14378839
46Steroid hormone biosynthesis_Homo sapiens_hsa001401.13898275
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.11269047
48Cardiac muscle contraction_Homo sapiens_hsa042601.08183550
49Glycerolipid metabolism_Homo sapiens_hsa005611.08144614
50Fat digestion and absorption_Homo sapiens_hsa049751.06703195
51Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.05815935
52Glutathione metabolism_Homo sapiens_hsa004801.04414364
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.03220175
54Staphylococcus aureus infection_Homo sapiens_hsa051501.03099775
55Caffeine metabolism_Homo sapiens_hsa002320.93807818
56Adipocytokine signaling pathway_Homo sapiens_hsa049200.92885677
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.91236767
58Retinol metabolism_Homo sapiens_hsa008300.90766921
59Parkinsons disease_Homo sapiens_hsa050120.90688871
60Drug metabolism - other enzymes_Homo sapiens_hsa009830.89021460
61Renin-angiotensin system_Homo sapiens_hsa046140.88313484
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.87854187
63Other glycan degradation_Homo sapiens_hsa005110.86835591
64Vitamin digestion and absorption_Homo sapiens_hsa049770.86138147
65Arachidonic acid metabolism_Homo sapiens_hsa005900.83497931
66Arginine and proline metabolism_Homo sapiens_hsa003300.83179738
67Phagosome_Homo sapiens_hsa041450.81745382
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.81246042
69ABC transporters_Homo sapiens_hsa020100.80620493
70Lysosome_Homo sapiens_hsa041420.80591785
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78563307
72Amoebiasis_Homo sapiens_hsa051460.75122954
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.73794251
74Insulin resistance_Homo sapiens_hsa049310.70728312
75Collecting duct acid secretion_Homo sapiens_hsa049660.70373541
76Metabolic pathways_Homo sapiens_hsa011000.70362966
77Malaria_Homo sapiens_hsa051440.69630882
78Alzheimers disease_Homo sapiens_hsa050100.66842442
79Protein digestion and absorption_Homo sapiens_hsa049740.66818143
80Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.66792918
81Proteoglycans in cancer_Homo sapiens_hsa052050.65686580
82PI3K-Akt signaling pathway_Homo sapiens_hsa041510.63916652
83Glycosaminoglycan degradation_Homo sapiens_hsa005310.63728947
84Vitamin B6 metabolism_Homo sapiens_hsa007500.61480642
85Galactose metabolism_Homo sapiens_hsa000520.61389860
86Linoleic acid metabolism_Homo sapiens_hsa005910.61304593
87Steroid biosynthesis_Homo sapiens_hsa001000.60254060
88TGF-beta signaling pathway_Homo sapiens_hsa043500.59968006
89ECM-receptor interaction_Homo sapiens_hsa045120.59771646
90Pertussis_Homo sapiens_hsa051330.59651218
91Sphingolipid metabolism_Homo sapiens_hsa006000.59579662
92Arginine biosynthesis_Homo sapiens_hsa002200.54811843
93Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54109574
94Proteasome_Homo sapiens_hsa030500.52870954
95Melanoma_Homo sapiens_hsa052180.50715442
96Rheumatoid arthritis_Homo sapiens_hsa053230.50596875
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.47892992
98Huntingtons disease_Homo sapiens_hsa050160.47392235
99Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45862473
100SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44317433
101Sulfur relay system_Homo sapiens_hsa041220.43833349
102Legionellosis_Homo sapiens_hsa051340.43680922
103Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.41886113
104Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.40608722
105Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.39137512
106AMPK signaling pathway_Homo sapiens_hsa041520.38986820
107Bladder cancer_Homo sapiens_hsa052190.38539998
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.38359144
109Mineral absorption_Homo sapiens_hsa049780.37733303
110Pentose phosphate pathway_Homo sapiens_hsa000300.35872902
111Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.35680948
112N-Glycan biosynthesis_Homo sapiens_hsa005100.34508587
113Asthma_Homo sapiens_hsa053100.32054990
114Ovarian steroidogenesis_Homo sapiens_hsa049130.31323308
115Autoimmune thyroid disease_Homo sapiens_hsa053200.30105564
116Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29315156
117Nitrogen metabolism_Homo sapiens_hsa009100.29203990
118Bile secretion_Homo sapiens_hsa049760.28048126
119Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.28012520
120Regulation of autophagy_Homo sapiens_hsa041400.27426691
121Circadian rhythm_Homo sapiens_hsa047100.27021013
122Fructose and mannose metabolism_Homo sapiens_hsa000510.24735638
123NF-kappa B signaling pathway_Homo sapiens_hsa040640.24120703
124Vibrio cholerae infection_Homo sapiens_hsa051100.22713173
125Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21965529

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