GIPC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1drug catabolic process (GO:0042737)6.49564852
2drug transmembrane transport (GO:0006855)6.27135272
3sulfate transmembrane transport (GO:1902358)6.10298643
4aminoglycoside antibiotic metabolic process (GO:0030647)6.08677339
5epoxygenase P450 pathway (GO:0019373)5.78723967
6drug transport (GO:0015893)5.78331851
7exogenous drug catabolic process (GO:0042738)5.64282737
8lipoprotein transport (GO:0042953)5.59201511
9very-low-density lipoprotein particle assembly (GO:0034379)5.58509880
10urate metabolic process (GO:0046415)5.39477304
11plasma lipoprotein particle assembly (GO:0034377)5.37694171
12sulfate transport (GO:0008272)5.36369096
13intestinal absorption (GO:0050892)5.32703716
14flavonoid metabolic process (GO:0009812)5.30167302
15sulfur compound transport (GO:0072348)5.23654447
16regulation of cholesterol esterification (GO:0010872)5.18837149
173-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)5.14901304
18purine ribonucleoside bisphosphate metabolic process (GO:0034035)5.14901304
19high-density lipoprotein particle remodeling (GO:0034375)4.83871839
20regulation of triglyceride catabolic process (GO:0010896)4.79514259
21protein-lipid complex assembly (GO:0065005)4.75291565
22organic cation transport (GO:0015695)4.71881502
23bundle of His cell to Purkinje myocyte communication (GO:0086069)4.71070929
24calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.63374962
25vitamin transmembrane transport (GO:0035461)4.61501248
26phospholipid efflux (GO:0033700)4.59137046
27renal absorption (GO:0070293)4.54049755
28NADH metabolic process (GO:0006734)4.52761069
29negative regulation of keratinocyte proliferation (GO:0010839)4.49737763
30fat-soluble vitamin biosynthetic process (GO:0042362)4.49373372
31protein-lipid complex remodeling (GO:0034368)4.44786849
32macromolecular complex remodeling (GO:0034367)4.44786849
33plasma lipoprotein particle remodeling (GO:0034369)4.44786849
34phosphate ion transport (GO:0006817)4.44064511
35actin filament depolymerization (GO:0030042)4.43411451
36bicarbonate transport (GO:0015701)4.42723439
37maintenance of gastrointestinal epithelium (GO:0030277)4.39863048
38intestinal epithelial cell development (GO:0060576)4.32140343
39excretion (GO:0007588)4.31290457
40oligosaccharide catabolic process (GO:0009313)4.29508033
41reverse cholesterol transport (GO:0043691)4.27782718
42phosphate ion homeostasis (GO:0055062)4.26103737
43trivalent inorganic anion homeostasis (GO:0072506)4.26103737
44cholesterol efflux (GO:0033344)4.21072010
45UDP-N-acetylglucosamine metabolic process (GO:0006047)4.20244642
46bile acid metabolic process (GO:0008206)4.19257442
47urea metabolic process (GO:0019627)4.16354644
48urea cycle (GO:0000050)4.08049252
49lipoprotein metabolic process (GO:0042157)4.07821969
50plasma lipoprotein particle organization (GO:0071827)4.07365298
51phosphate ion transmembrane transport (GO:0035435)4.05465489
52regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.04628978
53endocrine process (GO:0050886)4.04628978
54regulation of systemic arterial blood pressure by hormone (GO:0001990)4.04628978
55cytidine metabolic process (GO:0046087)4.03023130
56cytidine catabolic process (GO:0006216)4.03023130
57cytidine deamination (GO:0009972)4.03023130
58hormone catabolic process (GO:0042447)4.01841640
59angiotensin maturation (GO:0002003)4.01233434
60triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.99704858
61peptide catabolic process (GO:0043171)3.93802190
62nonribosomal peptide biosynthetic process (GO:0019184)3.92048190
63modified amino acid transport (GO:0072337)3.86738574
64low-density lipoprotein particle remodeling (GO:0034374)3.85718832
65regulation of guanylate cyclase activity (GO:0031282)3.84782562
66diacylglycerol metabolic process (GO:0046339)3.83224807
67regulation of cholesterol homeostasis (GO:2000188)3.81284531
68protein-lipid complex subunit organization (GO:0071825)3.81226232
69renal system process involved in regulation of blood volume (GO:0001977)3.81220777
70cholesterol homeostasis (GO:0042632)3.78352585
71vitamin D metabolic process (GO:0042359)3.75633502
72sterol homeostasis (GO:0055092)3.75501488
73nitrogen cycle metabolic process (GO:0071941)3.75109976
74surfactant homeostasis (GO:0043129)3.73177830
75hepatocyte apoptotic process (GO:0097284)3.73001588
76ethanol oxidation (GO:0006069)3.70462161
77vitamin transport (GO:0051180)3.68203860
78regulation of protein activation cascade (GO:2000257)3.64391526
79glomerulus development (GO:0032835)3.60004467
80pyrimidine ribonucleoside catabolic process (GO:0046133)3.59731193
81O-glycan processing (GO:0016266)3.59244566
82desmosome organization (GO:0002934)3.58693639
83glutathione biosynthetic process (GO:0006750)3.58636254
84renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.58620456
85positive regulation of glycoprotein biosynthetic process (GO:0010560)3.57473228
86transepithelial transport (GO:0070633)3.56101172
87regulation of complement activation (GO:0030449)3.53660326
88positive regulation of guanylate cyclase activity (GO:0031284)3.50606368
89regulation of systemic arterial blood pressure (GO:0003073)3.49368779
90pyrimidine-containing compound transmembrane transport (GO:0072531)3.48570095
91bile acid and bile salt transport (GO:0015721)3.47568365
92glycoside metabolic process (GO:0016137)3.44453697
93cGMP-mediated signaling (GO:0019934)3.41122142
94fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.40314784
95drinking behavior (GO:0042756)3.37956686
96glutathione derivative metabolic process (GO:1901685)3.37190778
97glutathione derivative biosynthetic process (GO:1901687)3.37190778
98regulation of cholesterol metabolic process (GO:0090181)3.36039128
99phospholipid homeostasis (GO:0055091)3.34835330
100arginine metabolic process (GO:0006525)3.31679959
101diol metabolic process (GO:0034311)3.29798836
102L-ascorbic acid metabolic process (GO:0019852)3.29539242
103heme transport (GO:0015886)3.28240197
104lysine catabolic process (GO:0006554)3.27194671
105lysine metabolic process (GO:0006553)3.27194671
106digestive system process (GO:0022600)3.24718040
107negative regulation of cholesterol transport (GO:0032375)3.23962442
108negative regulation of sterol transport (GO:0032372)3.23962442
109midgut development (GO:0007494)3.23891345
110regulation of vitamin metabolic process (GO:0030656)3.23643796
111cellular ketone body metabolic process (GO:0046950)3.23600113
112regulation of keratinocyte proliferation (GO:0010837)3.21801707
113fructose metabolic process (GO:0006000)3.20311740
114positive regulation of glycoprotein metabolic process (GO:1903020)3.18533431
115positive regulation of lipoprotein lipase activity (GO:0051006)3.17068145
116positive regulation of triglyceride lipase activity (GO:0061365)3.17068145
117negative regulation of fibrinolysis (GO:0051918)3.16756451
118regulation of bile acid biosynthetic process (GO:0070857)3.14369703
119alkaloid metabolic process (GO:0009820)3.12873617
120positive regulation of lipid catabolic process (GO:0050996)3.10729048
121toxin transport (GO:1901998)3.10662910
122homocysteine metabolic process (GO:0050667)3.10240200
123response to hepatocyte growth factor (GO:0035728)3.09578466
124cellular response to hepatocyte growth factor stimulus (GO:0035729)3.09578466
125adhesion of symbiont to host cell (GO:0044650)3.09569011
126virion attachment to host cell (GO:0019062)3.09569011
127membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.09510017
128vitamin A metabolic process (GO:0006776)3.08861895
129neurotransmitter biosynthetic process (GO:0042136)3.08552498
130cellular response to vitamin D (GO:0071305)3.08332811
131lipid homeostasis (GO:0055088)3.08303342
132sulfur amino acid catabolic process (GO:0000098)3.07348435
133regulation of cellular extravasation (GO:0002691)3.07327464
134positive regulation of steroid metabolic process (GO:0045940)3.05678625
135cellular glucuronidation (GO:0052695)3.05659904
136regulation of cGMP biosynthetic process (GO:0030826)3.05333242
137transcytosis (GO:0045056)3.04315870
138uronic acid metabolic process (GO:0006063)3.03559347
139glucuronate metabolic process (GO:0019585)3.03559347
140peptide biosynthetic process (GO:0043043)3.03521031
141polyol transport (GO:0015791)3.02577350
142nucleotide-sugar biosynthetic process (GO:0009226)3.02365013
143triglyceride homeostasis (GO:0070328)3.02086381
144acylglycerol homeostasis (GO:0055090)3.02086381
145quaternary ammonium group transport (GO:0015697)3.01983336
146adhesion of symbiont to host (GO:0044406)3.01254827
147short-chain fatty acid metabolic process (GO:0046459)3.00667445
148regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.98397080
149fat-soluble vitamin metabolic process (GO:0006775)2.98254444
150sphingoid metabolic process (GO:0046519)2.97487533
151negative regulation of blood coagulation (GO:0030195)2.97457908
152negative regulation of hemostasis (GO:1900047)2.97457908
153epithelial structure maintenance (GO:0010669)2.96955903
154cellular anion homeostasis (GO:0030002)2.94655723
155glutathione metabolic process (GO:0006749)2.93964622
156intestinal cholesterol absorption (GO:0030299)2.92671837
157cysteine metabolic process (GO:0006534)2.91962280
158negative regulation of coagulation (GO:0050819)2.91513757
159vitamin biosynthetic process (GO:0009110)2.91405972
160sulfation (GO:0051923)2.91062185
161sterol transport (GO:0015918)2.90488147
162cholesterol transport (GO:0030301)2.90488147
163chemical homeostasis within a tissue (GO:0048875)2.89794745
164nucleotide transmembrane transport (GO:1901679)2.88782091
165drug metabolic process (GO:0017144)2.88352787
166regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.87332725
167digestion (GO:0007586)2.86004559
168diterpenoid biosynthetic process (GO:0016102)2.83776449
169fucose metabolic process (GO:0006004)2.76466029
170ethanol metabolic process (GO:0006067)2.74527040
171striated muscle atrophy (GO:0014891)2.74073040
172positive regulation of digestive system process (GO:0060456)2.73670641
173membrane repolarization during action potential (GO:0086011)2.72172097
174positive regulation of epidermal cell differentiation (GO:0045606)2.72057810

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.75906712
2CDX2_20551321_ChIP-Seq_CACO-2_Human4.60529089
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.02844795
4CDX2_19796622_ChIP-Seq_MESCs_Mouse3.43730520
5SOX2_27498859_Chip-Seq_STOMACH_Mouse3.28348818
6CHD7_19251738_ChIP-ChIP_MESCs_Mouse3.03173911
7GATA4_25053715_ChIP-Seq_YYC3_Human3.01390057
8* SOX2_20726797_ChIP-Seq_SW620_Human2.99061511
9* HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.83469501
10STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.72476859
11FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.72222504
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.71970741
13ESR1_21235772_ChIP-Seq_MCF-7_Human2.64179043
14FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.55313592
15SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.54364326
16GATA6_25053715_ChIP-Seq_YYC3_Human2.49115076
17BP1_19119308_ChIP-ChIP_Hs578T_Human2.09440477
18NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.94176434
19TCF4_18268006_ChIP-ChIP_LS174T_Human1.93432968
20PPARA_22158963_ChIP-Seq_LIVER_Mouse1.83979495
21VDR_22108803_ChIP-Seq_LS180_Human1.81392452
22AR_21909140_ChIP-Seq_LNCAP_Human1.74730513
23RXR_22158963_ChIP-Seq_LIVER_Mouse1.66330652
24EGR1_23403033_ChIP-Seq_LIVER_Mouse1.65884828
25ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.65562746
26PCGF2_27294783_Chip-Seq_NPCs_Mouse1.64856499
27PPAR_26484153_Chip-Seq_NCI-H1993_Human1.63315656
28KAP1_22055183_ChIP-Seq_ESCs_Mouse1.63159284
29TRIM28_21343339_ChIP-Seq_HEK293_Human1.61788282
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.60715719
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.60218030
32ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.58879295
33PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.56960338
34ESR2_21235772_ChIP-Seq_MCF-7_Human1.56864810
35LXR_22158963_ChIP-Seq_LIVER_Mouse1.56289897
36FOXM1_26456572_ChIP-Seq_MCF-7_Human1.50106613
37ESR1_20079471_ChIP-ChIP_T-47D_Human1.47297590
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45016506
39FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.44991224
40PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44832271
41PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.43139843
42FOXO3_23340844_ChIP-Seq_DLD1_Human1.43124322
43SUZ12_27294783_Chip-Seq_NPCs_Mouse1.38992432
44KLF5_25053715_ChIP-Seq_YYC3_Human1.38374094
45* CDX2_22108803_ChIP-Seq_LS180_Human1.35241759
46GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.34815080
47ZNF217_24962896_ChIP-Seq_MCF-7_Human1.33846439
48BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.30886498
49TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.30321831
50* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.29138703
51NFE2_27457419_Chip-Seq_LIVER_Mouse1.29105641
52* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.26195879
53NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.24597202
54EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.24327860
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.21219260
56JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.21053134
57* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.21035278
58TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.20318276
59GATA2_21666600_ChIP-Seq_HMVEC_Human1.18937968
60AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.17116418
61* HNF4A_19822575_ChIP-Seq_HepG2_Human1.16871477
62BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16686548
63CEBPB_22108803_ChIP-Seq_LS180_Human1.16431120
64SMAD3_21741376_ChIP-Seq_HESCs_Human1.16295950
65SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.15475573
66SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.15475573
67CJUN_26792858_Chip-Seq_BT549_Human1.15353520
68POU3F2_20337985_ChIP-ChIP_501MEL_Human1.14478974
69EZH2_27294783_Chip-Seq_NPCs_Mouse1.13700499
70BCAT_22108803_ChIP-Seq_LS180_Human1.13509674
71RARG_19884340_ChIP-ChIP_MEFs_Mouse1.13417113
72FLI1_27457419_Chip-Seq_LIVER_Mouse1.10892481
73CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.10732422
74TCF4_22108803_ChIP-Seq_LS180_Human1.10392096
75ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.09643422
76FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.09371028
77FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.09072887
78FOXA1_21572438_ChIP-Seq_LNCaP_Human1.08621154
79PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.07889537
80NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07255874
81RXR_22108803_ChIP-Seq_LS180_Human1.04332462
82EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.04250031
83* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.02265234
84* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.02265234
85IRF8_22096565_ChIP-ChIP_GC-B_Human1.00654252
86RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00287626
87ESRRB_18555785_Chip-Seq_ESCs_Mouse0.98924229
88GATA3_24758297_ChIP-Seq_MCF-7_Human0.98893051
89KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98866519
90CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.97953340
91* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.95882102
92STAT1_17558387_ChIP-Seq_HELA_Human0.95670819
93EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94767418
94KLF5_20875108_ChIP-Seq_MESCs_Mouse0.92176032
95RUNX1_27514584_Chip-Seq_MCF-7_Human0.91679686
96RACK7_27058665_Chip-Seq_MCF-7_Human0.89837105
97BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.89490971
98KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.89361178
99* SOX2_19829295_ChIP-Seq_ESCs_Human0.88398630
100* NANOG_19829295_ChIP-Seq_ESCs_Human0.88398630
101SALL1_21062744_ChIP-ChIP_HESCs_Human0.88350862
102AR_20517297_ChIP-Seq_VCAP_Human0.87886130
103* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.87747777
104JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87516580
105TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87515227
106ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.87084836
107AHR_22903824_ChIP-Seq_MCF-7_Human0.86607159
108SUZ12_18555785_Chip-Seq_ESCs_Mouse0.86593794
109STAT3_18555785_Chip-Seq_ESCs_Mouse0.86012325
110CLOCK_20551151_ChIP-Seq_293T_Human0.85033734
111* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.84864598
112SMAD1_18555785_Chip-Seq_ESCs_Mouse0.83894999
113PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.83692823
114STAT6_21828071_ChIP-Seq_BEAS2B_Human0.83167750
115VDR_24787735_ChIP-Seq_THP-1_Human0.83066250
116* PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.82679536
117* TP63_23658742_ChIP-Seq_EP156T_Human0.82236013
118TAL1_26923725_Chip-Seq_HPCs_Mouse0.81762143
119SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.81632939
120ZFX_18555785_Chip-Seq_ESCs_Mouse0.81307815
121EGR1_19032775_ChIP-ChIP_M12_Human0.81160908
122* CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.81030361
123ZNF263_19887448_ChIP-Seq_K562_Human0.81014441
124* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.80395482
125PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.80207211
126* CMYC_18555785_Chip-Seq_ESCs_Mouse0.79630834
127PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.79561769
128FOXA2_19822575_ChIP-Seq_HepG2_Human0.79510261
129EP300_21415370_ChIP-Seq_HL-1_Mouse0.79132599
130ATF3_27146783_Chip-Seq_COLON_Human0.78874789
131FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.78733227
132TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.78284579
133GATA1_22025678_ChIP-Seq_K562_Human0.77778222
134P63_26484246_Chip-Seq_KERATINOCYTES_Human0.77683844
135P53_22387025_ChIP-Seq_ESCs_Mouse0.77452387
136CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.77448715
137FOXA1_25552417_ChIP-Seq_VCAP_Human0.77310411
138NCOR_22424771_ChIP-Seq_293T_Human0.76344949

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis5.37060524
2MP0003878_abnormal_ear_physiology4.63985695
3MP0005377_hearing/vestibular/ear_phenot4.63985695
4MP0010234_abnormal_vibrissa_follicle4.26871773
5MP0004264_abnormal_extraembryonic_tissu3.73685223
6MP0004043_abnormal_pH_regulation3.73094796
7MP0004019_abnormal_vitamin_homeostasis3.54287350
8MP0009840_abnormal_foam_cell3.39320309
9MP0000462_abnormal_digestive_system2.99246974
10MP0001666_abnormal_nutrient_absorption2.94190093
11MP0002822_catalepsy2.74004296
12MP0008875_abnormal_xenobiotic_pharmacok2.60485311
13MP0008004_abnormal_stomach_pH2.58864543
14MP0002138_abnormal_hepatobiliary_system2.58859995
15MP0001765_abnormal_ion_homeostasis2.54786919
16MP0003866_abnormal_defecation2.50115257
17MP0001873_stomach_inflammation2.48488968
18MP0002139_abnormal_hepatobiliary_system2.45068548
19MP0009643_abnormal_urine_homeostasis2.41209079
20MP0005085_abnormal_gallbladder_physiolo2.36941331
21MP0001663_abnormal_digestive_system2.27243567
22MP0005381_digestive/alimentary_phenotyp2.21537158
23MP0003252_abnormal_bile_duct2.18702075
24MP0003283_abnormal_digestive_organ2.12639244
25MP0000538_abnormal_urinary_bladder2.12476030
26MP0003941_abnormal_skin_development2.03660290
27MP0002277_abnormal_respiratory_mucosa2.02061027
28MP0000490_abnormal_crypts_of2.00808774
29MP0005636_abnormal_mineral_homeostasis1.98566504
30MP0005332_abnormal_amino_acid1.97874477
31MP0001664_abnormal_digestion1.95732278
32MP0010155_abnormal_intestine_physiology1.92507704
33MP0000566_synostosis1.92034088
34MP0004782_abnormal_surfactant_physiolog1.89862848
35MP0009379_abnormal_foot_pigmentation1.85955236
36MP0001756_abnormal_urination1.80887445
37MP0009697_abnormal_copulation1.80610916
38MP0002136_abnormal_kidney_physiology1.78980128
39MP0005167_abnormal_blood-brain_barrier1.68354596
40MP0003315_abnormal_perineum_morphology1.66354637
41MP0005084_abnormal_gallbladder_morpholo1.66038515
42MP0005365_abnormal_bile_salt1.63849353
43MP0004147_increased_porphyrin_level1.63626551
44MP0000477_abnormal_intestine_morphology1.58405942
45MP0003300_gastrointestinal_ulcer1.53367195
46MP0003191_abnormal_cellular_cholesterol1.53111543
47MP0005409_darkened_coat_color1.43943722
48MP0005451_abnormal_body_composition1.37980506
49MP0003718_maternal_effect1.36588301
50MP0002796_impaired_skin_barrier1.33991318
51MP0005257_abnormal_intraocular_pressure1.31761373
52MP0010386_abnormal_urinary_bladder1.29436162
53MP0000013_abnormal_adipose_tissue1.28515263
54MP0005310_abnormal_salivary_gland1.25708806
55MP0000678_abnormal_parathyroid_gland1.23823121
56MP0000537_abnormal_urethra_morphology1.22637581
57MP0002132_abnormal_respiratory_system1.16834048
58MP0000609_abnormal_liver_physiology1.15620943
59MP0009780_abnormal_chondrocyte_physiolo1.15200540
60MP0002876_abnormal_thyroid_physiology1.15154383
61MP0002098_abnormal_vibrissa_morphology1.07942465
62MP0000470_abnormal_stomach_morphology1.05174105
63MP0003183_abnormal_peptide_metabolism1.00511835
64MP0010368_abnormal_lymphatic_system0.99805787
65MP0005501_abnormal_skin_physiology0.96920877
66MP0003453_abnormal_keratinocyte_physiol0.96642849
67MP0001501_abnormal_sleep_pattern0.94880563
68MP0001958_emphysema0.93780344
69MP0003806_abnormal_nucleotide_metabolis0.93406678
70MP0004484_altered_response_of0.90435628
71MP0003950_abnormal_plasma_membrane0.88379673
72MP0005166_decreased_susceptibility_to0.86427172
73MP0005448_abnormal_energy_balance0.84272572
74MP0003868_abnormal_feces_composition0.83668036
75MP0010678_abnormal_skin_adnexa0.82637694
76MP0003693_abnormal_embryo_hatching0.82613507
77MP0005058_abnormal_lysosome_morphology0.79857431
78MP0003186_abnormal_redox_activity0.79811945
79MP0000613_abnormal_salivary_gland0.78137830
80MP0001849_ear_inflammation0.77675938
81MP0002971_abnormal_brown_adipose0.76425854
82MP0002163_abnormal_gland_morphology0.76242502
83MP0003879_abnormal_hair_cell0.71464183
84MP0003943_abnormal_hepatobiliary_system0.70449413
85MP0005584_abnormal_enzyme/coenzyme_acti0.67970864
86MP0005535_abnormal_body_temperature0.67118126
87MP0009115_abnormal_fat_cell0.67029650
88MP0003953_abnormal_hormone_level0.66968741
89MP0001216_abnormal_epidermal_layer0.66240632
90MP0005395_other_phenotype0.65082358
91MP0005376_homeostasis/metabolism_phenot0.63299544
92MP0002928_abnormal_bile_duct0.62575152
93MP0003656_abnormal_erythrocyte_physiolo0.62533180
94MP0003195_calcinosis0.62207270
95MP0000598_abnormal_liver_morphology0.60653219
96MP0003724_increased_susceptibility_to0.59622546
97MP0000230_abnormal_systemic_arterial0.59146278
98MP0003638_abnormal_response/metabolism_0.58654356
99MP0010329_abnormal_lipoprotein_level0.58324582
100MP0008469_abnormal_protein_level0.57898127
101MP0000762_abnormal_tongue_morphology0.57701262
102MP0005319_abnormal_enzyme/_coenzyme0.57416647
103MP0001845_abnormal_inflammatory_respons0.56831816
104MP0009764_decreased_sensitivity_to0.56671206
105MP0001661_extended_life_span0.54361143
106MP0009785_altered_susceptibility_to0.54190877
107MP0002078_abnormal_glucose_homeostasis0.53179062
108MP0005367_renal/urinary_system_phenotyp0.52423960
109MP0000516_abnormal_urinary_system0.52423960
110MP0006054_spinal_hemorrhage0.51896921
111MP0005408_hypopigmentation0.51621532
112MP0010352_gastrointestinal_tract_polyps0.51110046
113MP0008872_abnormal_physiological_respon0.50463832
114MP0001764_abnormal_homeostasis0.50044839
115MP0001346_abnormal_lacrimal_gland0.49069151
116MP0002896_abnormal_bone_mineralization0.49058764
117MP0002135_abnormal_kidney_morphology0.48900877
118MP0001188_hyperpigmentation0.48529253
119MP0002089_abnormal_postnatal_growth/wei0.48082264
120MP0009642_abnormal_blood_homeostasis0.46435616
121MP0000249_abnormal_blood_vessel0.46162912
122MP0000639_abnormal_adrenal_gland0.46035833
123MP0002118_abnormal_lipid_homeostasis0.45761148
124MP0005334_abnormal_fat_pad0.44649985
125MP0005023_abnormal_wound_healing0.44534413
126MP0001485_abnormal_pinna_reflex0.43991546
127MP0002166_altered_tumor_susceptibility0.42945417
128MP0005670_abnormal_white_adipose0.42674426
129MP0004947_skin_inflammation0.42359209
130MP0005666_abnormal_adipose_tissue0.41404341
131MP0005410_abnormal_fertilization0.40415015
132MP0009333_abnormal_splenocyte_physiolog0.40129827
133MP0000681_abnormal_thyroid_gland0.39979412
134MP0002160_abnormal_reproductive_system0.39575262

Predicted human phenotypes

RankGene SetZ-score
1Hyperactive renin-angiotensin system (HP:0000841)7.80085791
2Metabolic alkalosis (HP:0200114)6.78976631
3Hypobetalipoproteinemia (HP:0003563)6.61908622
4Abnormality of chloride homeostasis (HP:0011422)6.55522922
5Fat malabsorption (HP:0002630)5.10131294
6Abnormality of glutamine family amino acid metabolism (HP:0010902)4.97607298
7Abnormality of monocarboxylic acid metabolism (HP:0010996)4.86956349
8Abnormality of renin-angiotensin system (HP:0000847)4.81025556
9Hyperaldosteronism (HP:0000859)4.62269960
10Acanthocytosis (HP:0001927)4.36727622
11Proximal tubulopathy (HP:0000114)4.34595231
12Hypomagnesemia (HP:0002917)4.32913492
13Hydroxyprolinuria (HP:0003080)4.32026077
14Abnormality of proline metabolism (HP:0010907)4.32026077
15Increased circulating renin level (HP:0000848)4.30726874
16Tetany (HP:0001281)4.20266404
17Abnormality of magnesium homeostasis (HP:0004921)4.17760115
18Ileus (HP:0002595)4.16793644
19Abnormality of renal excretion (HP:0011036)4.04849321
20Hypolipoproteinemia (HP:0010981)4.03823238
21Hypokalemic alkalosis (HP:0001949)4.00598511
22Systemic lupus erythematosus (HP:0002725)3.95656905
23Deep venous thrombosis (HP:0002625)3.93438166
24Gout (HP:0001997)3.93296744
25Alkalosis (HP:0001948)3.90903292
26Complement deficiency (HP:0004431)3.88645666
27Abnormal urine output (HP:0012590)3.88295667
28Polyuria (HP:0000103)3.82834268
29Malnutrition (HP:0004395)3.76606991
30Increased purine levels (HP:0004368)3.60985026
31Hyperuricemia (HP:0002149)3.60985026
32Osteomalacia (HP:0002749)3.59291346
33Steatorrhea (HP:0002570)3.58510738
34Pigmentary retinal degeneration (HP:0001146)3.46867345
35Glycosuria (HP:0003076)3.41471616
36Abnormality of urine glucose concentration (HP:0011016)3.41471616
37Dehydration (HP:0001944)3.40035205
38Focal segmental glomerulosclerosis (HP:0000097)3.36382575
39Xanthomatosis (HP:0000991)3.33989420
40Hypokalemia (HP:0002900)3.29296622
41Right ventricular cardiomyopathy (HP:0011663)3.24993990
42Intrahepatic cholestasis (HP:0001406)3.23030060
43Abnormality of purine metabolism (HP:0004352)3.18888441
44Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.18442626
45Abnormal tarsal ossification (HP:0008369)3.15157297
46Hyperglycinuria (HP:0003108)3.11247809
47Abnormality of carpal bone ossification (HP:0006257)3.10245730
48Renal salt wasting (HP:0000127)3.07080376
49Abnormality of complement system (HP:0005339)3.05372232
50Glomerulonephritis (HP:0000099)3.04860097
51Congenital sensorineural hearing impairment (HP:0008527)3.03003694
52Glomerulosclerosis (HP:0000096)3.01618246
53Abnormal drinking behavior (HP:0030082)3.00942514
54Polydipsia (HP:0001959)3.00942514
55Hypophosphatemic rickets (HP:0004912)2.99469221
56Flat acetabular roof (HP:0003180)2.99343557
57Prolonged partial thromboplastin time (HP:0003645)2.96302864
58Thin bony cortex (HP:0002753)2.96058445
59Cupped ribs (HP:0000887)2.95618073
60Hypercalciuria (HP:0002150)2.87049527
61Generalized aminoaciduria (HP:0002909)2.83252681
62Abdominal distention (HP:0003270)2.82899575
63Widely patent fontanelles and sutures (HP:0004492)2.81844395
64Decreased circulating renin level (HP:0003351)2.78392358
65Epidermoid cyst (HP:0200040)2.77865740
66Abnormality of potassium homeostasis (HP:0011042)2.76782953
67Vacuolated lymphocytes (HP:0001922)2.76151687
68Chronic diarrhea (HP:0002028)2.64438516
69Hyperphosphaturia (HP:0003109)2.60851581
70Abnormal urine phosphate concentration (HP:0012599)2.57570009
71Hyperammonemia (HP:0001987)2.54782599
72Abnormality of the vitamin B12 metabolism (HP:0004341)2.52190061
73Abnormality of aromatic amino acid family metabolism (HP:0004338)2.49083153
74Hyponatremia (HP:0002902)2.48648835
75Delayed epiphyseal ossification (HP:0002663)2.47465311
76Abnormality of pyrimidine metabolism (HP:0004353)2.36662371
77Abnormality of vitamin B metabolism (HP:0004340)2.35880909
78Abnormal hand bone ossification (HP:0010660)2.33529617
79Hemorrhage of the eye (HP:0011885)2.30971391
80Abnormal biliary tract morphology (HP:0012440)2.30247417
81Megaloblastic anemia (HP:0001889)2.29893564
82Hypoglycemic coma (HP:0001325)2.29820152
83Abnormality of nucleobase metabolism (HP:0010932)2.27562212
84Pustule (HP:0200039)2.26593880
85Renal tubular acidosis (HP:0001947)2.25471110
86Hyperlipoproteinemia (HP:0010980)2.22211485
87Villous atrophy (HP:0011473)2.21366200
88Abnormality of small intestinal villus morphology (HP:0011472)2.21366200
89Gonadal dysgenesis (HP:0000133)2.20903877
90Hypotension (HP:0002615)2.20569340
91Spontaneous abortion (HP:0005268)2.20502121
92Abnormality of the 1st metacarpal (HP:0010009)2.19222014
93Vascular calcification (HP:0004934)2.18989887
94Enlarged epiphyses (HP:0010580)2.17495823
95Hypophosphatemia (HP:0002148)2.16704079
96Abnormal ossification of hand bones (HP:0005921)2.15557311
97Nephrolithiasis (HP:0000787)2.14078464
98Poikilocytosis (HP:0004447)2.13823818
99Wide cranial sutures (HP:0010537)2.13680511
100Joint hemorrhage (HP:0005261)2.12874390
101Abnormality of sodium homeostasis (HP:0010931)2.11317371
102Conjugated hyperbilirubinemia (HP:0002908)2.10348140
103Abnormality of dicarboxylic acid metabolism (HP:0010995)2.09851691
104Dicarboxylic aciduria (HP:0003215)2.09851691
105Confusion (HP:0001289)2.07901624
106Cheilitis (HP:0100825)2.07615493
107Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.05173913
108Abnormality of glycine metabolism (HP:0010895)2.04466152
109Abnormality of serine family amino acid metabolism (HP:0010894)2.04466152
110Metaphyseal irregularity (HP:0003025)2.03735396
111Nausea (HP:0002018)2.02323382
112Abnormal foot bone ossification (HP:0010675)2.02035006
113Abnormality of sulfur amino acid metabolism (HP:0004339)2.01316723
114Hyperphosphatemia (HP:0002905)2.00821055
115Hypoalphalipoproteinemia (HP:0003233)1.98829618
116Abnormality of fatty-acid metabolism (HP:0004359)1.97914099
117Abnormality of aspartate family amino acid metabolism (HP:0010899)1.97244780
118Neonatal short-limb short stature (HP:0008921)1.97148465
119Adrenal overactivity (HP:0002717)1.96469558
120Nephritis (HP:0000123)1.93409288
121Facial shape deformation (HP:0011334)1.92613719
122Potter facies (HP:0002009)1.92613719
123Metabolic acidosis (HP:0001942)1.92054704
124Shawl scrotum (HP:0000049)1.91079321
125Rectal prolapse (HP:0002035)1.90805180
126Pancreatitis (HP:0001733)1.90541686
127Abnormality of renal resorption (HP:0011038)1.90169149
128Abnormality of the nasal septum (HP:0000419)1.89483878
129Prostate neoplasm (HP:0100787)1.86229172
130Abnormality of the common coagulation pathway (HP:0010990)1.85209078
131Visceral angiomatosis (HP:0100761)1.84917574
132Tubular atrophy (HP:0000092)1.84864939
133Alveolar cell carcinoma (HP:0006519)1.82874305
134Hypercholesterolemia (HP:0003124)1.81206194
135Cardiovascular calcification (HP:0011915)1.80710164
136Autoimmune thrombocytopenia (HP:0001973)1.79096298
137Abnormality of the renal cortex (HP:0011035)1.77287747
138Renal cortical cysts (HP:0000803)1.76313313
139Rickets (HP:0002748)1.74744956
140Abnormality of the middle phalanges of the toes (HP:0010183)1.74457836
141Symphalangism affecting the phalanges of the hand (HP:0009773)1.74365275
142Abnormality of the costochondral junction (HP:0000919)1.73231090
143Abnormality of the distal phalanx of the thumb (HP:0009617)1.71948543
144Abnormality of vitamin metabolism (HP:0100508)1.71654579
145Symptomatic seizures (HP:0011145)1.71315930
146Ketoacidosis (HP:0001993)1.71311471

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B5.15953629
2MST1R4.98409452
3MST44.49654105
4PIK3CA4.10476180
5WNK43.76678911
6STK38L3.70652785
7WNK33.63107504
8LMTK23.53573098
9OXSR13.28879321
10FRK3.26358086
11TNIK2.58893732
12NUAK12.57435728
13BRSK22.47823073
14FGFR32.46728800
15EPHB22.44529600
16MAP2K22.38579270
17NLK2.38486462
18PRKG22.33487239
19FGFR42.30407303
20PINK12.25005194
21EPHA22.18669408
22ERN12.11795615
23TTK2.05818481
24CAMKK21.96068158
25STK391.68518003
26MYLK1.61866908
27CDK81.46232315
28ZAK1.44171256
29LATS11.33548813
30ERBB41.33385020
31DMPK1.33312550
32MAP3K21.32377418
33NME11.30732069
34FGFR21.25716430
35TAOK31.21415432
36MET1.18190691
37MAP3K141.10565229
38BCR1.08905538
39IRAK31.07624536
40BRAF1.07080889
41TESK11.06330632
42INSRR1.04328906
43AKT31.02571572
44TBK10.98022715
45TGFBR20.90594181
46FGFR10.90162269
47PRKCI0.90139738
48STK100.89904191
49PIK3CG0.88427474
50GRK60.82360550
51PRKCE0.80760565
52TEC0.79049705
53MAP2K10.78893120
54MAP3K100.74938559
55PRKACG0.73483200
56TRIM280.73135048
57STK30.71701851
58GRK10.71064300
59PRKAA20.70748422
60TIE10.69848115
61BMPR1B0.69773346
62MAP3K120.68361194
63SIK30.65864471
64IKBKE0.65352763
65PDK20.65208624
66NEK90.65162898
67DAPK20.62726761
68PIM20.62460367
69WNK10.61917857
70PDK10.61680176
71TRPM70.61537268
72MAP3K80.61175163
73RIPK10.60595501
74STK380.60481992
75EIF2AK30.60049041
76MAPKAPK30.59751506
77PDPK10.58967699
78IRAK10.58671550
79PLK40.58539161
80SGK2230.58201544
81SGK4940.58201544
82MAPK150.57944669
83PAK40.57566072
84TAOK10.57487223
85ERBB30.55345969
86MAP3K70.54978084
87FER0.53382196
88ABL20.53270058
89BMPR20.52854936
90DDR20.52756814
91MAP2K40.52687434
92ARAF0.52675452
93MAPK110.51676538
94MATK0.51239124
95AURKB0.51028327
96PTK20.50917761
97ITK0.50742649
98MAP3K10.50462096
99BCKDK0.49582475
100SGK30.48953629
101PRKAA10.48888815
102CAMK2D0.47026359
103EIF2AK10.46394743
104CDK90.46176352
105SGK20.46051961
106MAP3K60.44978735
107MELK0.44302686
108ERBB20.44167804
109PRKD20.43615829
110MAP3K130.43437510
111MAP2K60.43133450
112PTK60.42111747
113PBK0.41652660
114MAP3K30.39887510
115MAP3K50.39747096
116GRK70.39453529
117STK240.38476017
118IGF1R0.37666653
119YES10.36287105
120RPS6KB10.35684056
121PRKCQ0.35476064
122PRKCA0.34936722
123AKT20.34592890
124CHEK20.32489508
125PRKG10.32107194
126CHUK0.32081965
127TESK20.30410523
128KSR20.30316335
129ROCK10.30068803
130SRC0.30002874
131PRKACA0.29679886
132CAMKK10.29525570
133TYK20.28428891
134CSNK1G10.27872044
135PRKCD0.26846594
136CSK0.26252590
137RET0.26024375
138BRD40.24936674
139CDK30.24410000
140PRKCZ0.24283300
141DAPK10.23564623
142CSNK1A10.22974465
143CAMK2G0.22435645
144MUSK0.21766477
145EIF2AK20.21430318
146CDK190.21241715
147RPS6KA20.21137005
148CAMK2B0.20027767
149BRSK10.18405657

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009205.22519583
2Mineral absorption_Homo sapiens_hsa049784.17671464
3Vitamin digestion and absorption_Homo sapiens_hsa049773.29867058
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.85918636
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.67087413
6Pentose and glucuronate interconversions_Homo sapiens_hsa000402.57802973
7Fat digestion and absorption_Homo sapiens_hsa049752.32611395
8Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.26006897
9Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.24772838
10Arginine biosynthesis_Homo sapiens_hsa002202.21835068
11Butanoate metabolism_Homo sapiens_hsa006502.16424472
12Histidine metabolism_Homo sapiens_hsa003402.13746301
13Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.12726193
14Renin-angiotensin system_Homo sapiens_hsa046141.98943716
15Glutathione metabolism_Homo sapiens_hsa004801.96243476
16Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.91085543
17Fructose and mannose metabolism_Homo sapiens_hsa000511.83698319
18Maturity onset diabetes of the young_Homo sapiens_hsa049501.80989309
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.80690452
20Bile secretion_Homo sapiens_hsa049761.80450984
21Complement and coagulation cascades_Homo sapiens_hsa046101.77024653
22Cyanoamino acid metabolism_Homo sapiens_hsa004601.76847287
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.75707329
24Protein digestion and absorption_Homo sapiens_hsa049741.74932350
25Tryptophan metabolism_Homo sapiens_hsa003801.71452367
26Fatty acid degradation_Homo sapiens_hsa000711.66866540
27Other glycan degradation_Homo sapiens_hsa005111.64671854
28Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.58018387
29beta-Alanine metabolism_Homo sapiens_hsa004101.55028277
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.49498798
31Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.49175621
32Folate biosynthesis_Homo sapiens_hsa007901.46311742
33Starch and sucrose metabolism_Homo sapiens_hsa005001.43054341
34Arachidonic acid metabolism_Homo sapiens_hsa005901.38391176
35Galactose metabolism_Homo sapiens_hsa000521.38225303
36Sphingolipid metabolism_Homo sapiens_hsa006001.33313854
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.30891917
38Sulfur relay system_Homo sapiens_hsa041221.30141526
39alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.30002458
40Propanoate metabolism_Homo sapiens_hsa006401.27086660
41Pyruvate metabolism_Homo sapiens_hsa006201.26540513
42Oxidative phosphorylation_Homo sapiens_hsa001901.25931546
43Arginine and proline metabolism_Homo sapiens_hsa003301.21871373
44Carbohydrate digestion and absorption_Homo sapiens_hsa049731.21129300
45Peroxisome_Homo sapiens_hsa041461.20058293
46Intestinal immune network for IgA production_Homo sapiens_hsa046721.17458150
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.16304805
48Chemical carcinogenesis_Homo sapiens_hsa052041.13671220
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.06801427
50Collecting duct acid secretion_Homo sapiens_hsa049661.03748640
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01236995
52Glycerolipid metabolism_Homo sapiens_hsa005610.94904247
53Linoleic acid metabolism_Homo sapiens_hsa005910.91666966
54PPAR signaling pathway_Homo sapiens_hsa033200.88159320
55Tight junction_Homo sapiens_hsa045300.87530833
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.85829701
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.83425424
58Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.80391081
59Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70533175
60Nitrogen metabolism_Homo sapiens_hsa009100.70396367
61Steroid hormone biosynthesis_Homo sapiens_hsa001400.70008268
62Parkinsons disease_Homo sapiens_hsa050120.69792281
63Retinol metabolism_Homo sapiens_hsa008300.68902370
64Hepatitis C_Homo sapiens_hsa051600.62987301
65Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.62761309
66Staphylococcus aureus infection_Homo sapiens_hsa051500.60809261
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60383679
68Phenylalanine metabolism_Homo sapiens_hsa003600.60158308
69Carbon metabolism_Homo sapiens_hsa012000.59954500
702-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59113571
71Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.59073631
72Metabolic pathways_Homo sapiens_hsa011000.59026081
73Ether lipid metabolism_Homo sapiens_hsa005650.57517126
74Fatty acid biosynthesis_Homo sapiens_hsa000610.57176193
75Thyroid hormone synthesis_Homo sapiens_hsa049180.56532352
76ABC transporters_Homo sapiens_hsa020100.55716900
77Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.55590535
78Pancreatic secretion_Homo sapiens_hsa049720.55298616
79Fatty acid metabolism_Homo sapiens_hsa012120.54920720
80Alzheimers disease_Homo sapiens_hsa050100.52414043
81Leukocyte transendothelial migration_Homo sapiens_hsa046700.51968283
82Fatty acid elongation_Homo sapiens_hsa000620.51154332
83Adherens junction_Homo sapiens_hsa045200.50393924
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.47818460
85Renin secretion_Homo sapiens_hsa049240.47678739
86Gastric acid secretion_Homo sapiens_hsa049710.45971773
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44681401
88Bladder cancer_Homo sapiens_hsa052190.44370405
89Huntingtons disease_Homo sapiens_hsa050160.44156862
90NOD-like receptor signaling pathway_Homo sapiens_hsa046210.36466009
91Pentose phosphate pathway_Homo sapiens_hsa000300.36354271
92Lysine degradation_Homo sapiens_hsa003100.34918388
93Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.34850397
94RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34668571
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.34421104
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.32261002
97Biosynthesis of amino acids_Homo sapiens_hsa012300.31781162
98Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.31352819
99Insulin resistance_Homo sapiens_hsa049310.29071391
100Vibrio cholerae infection_Homo sapiens_hsa051100.29037757
101Selenocompound metabolism_Homo sapiens_hsa004500.28621588
102NF-kappa B signaling pathway_Homo sapiens_hsa040640.28352944
103Cysteine and methionine metabolism_Homo sapiens_hsa002700.24860819
104Glucagon signaling pathway_Homo sapiens_hsa049220.24050781
105Ovarian steroidogenesis_Homo sapiens_hsa049130.23869889
106Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.23605532
107Vitamin B6 metabolism_Homo sapiens_hsa007500.23017396
108Rheumatoid arthritis_Homo sapiens_hsa053230.21961236
109Lysosome_Homo sapiens_hsa041420.21367963
110Caffeine metabolism_Homo sapiens_hsa002320.20919613
111Tyrosine metabolism_Homo sapiens_hsa003500.20302587
112Salmonella infection_Homo sapiens_hsa051320.20041469
113Steroid biosynthesis_Homo sapiens_hsa001000.19854141
114Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.17145041
115Cardiac muscle contraction_Homo sapiens_hsa042600.16921042
116Hematopoietic cell lineage_Homo sapiens_hsa046400.16752240
117Influenza A_Homo sapiens_hsa051640.16540918
118Choline metabolism in cancer_Homo sapiens_hsa052310.15962064
119Adipocytokine signaling pathway_Homo sapiens_hsa049200.15935970
120African trypanosomiasis_Homo sapiens_hsa051430.14574108
121Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.13834665
122Serotonergic synapse_Homo sapiens_hsa047260.12961771
123Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.11538896
124Pertussis_Homo sapiens_hsa051330.11321802
125AMPK signaling pathway_Homo sapiens_hsa041520.04142746
126Aldosterone synthesis and secretion_Homo sapiens_hsa04925-0.0237209
127Inositol phosphate metabolism_Homo sapiens_hsa00562-0.0166899
128Circadian rhythm_Homo sapiens_hsa04710-0.0134517
129Asthma_Homo sapiens_hsa05310-0.0003833

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