GIT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.28431280
2locomotory exploration behavior (GO:0035641)5.75868391
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.66445705
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.21612576
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.18560587
6synaptic vesicle docking involved in exocytosis (GO:0016081)5.18120412
7vocalization behavior (GO:0071625)4.65923094
8glutamate secretion (GO:0014047)4.62922157
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.53724150
10synaptic vesicle exocytosis (GO:0016079)4.51396659
11layer formation in cerebral cortex (GO:0021819)4.42526432
12regulation of synapse structural plasticity (GO:0051823)4.40700381
13regulation of synaptic vesicle exocytosis (GO:2000300)4.35053156
14regulation of glutamate receptor signaling pathway (GO:1900449)4.34201406
15regulation of neuronal synaptic plasticity (GO:0048168)4.30830671
16exploration behavior (GO:0035640)4.14022276
17sodium ion export (GO:0071436)4.12646305
18regulation of long-term neuronal synaptic plasticity (GO:0048169)4.10826603
19cerebellar granule cell differentiation (GO:0021707)4.07249583
20dendritic spine morphogenesis (GO:0060997)3.95786435
21regulation of synaptic vesicle transport (GO:1902803)3.90771617
22amino acid import (GO:0043090)3.77691567
23neurotransmitter secretion (GO:0007269)3.76254874
24protein localization to synapse (GO:0035418)3.72274142
25sperm motility (GO:0030317)3.71454630
26activation of protein kinase A activity (GO:0034199)3.69996049
27calcium ion-dependent exocytosis (GO:0017156)3.69925359
28acrosome reaction (GO:0007340)3.68394889
29ionotropic glutamate receptor signaling pathway (GO:0035235)3.67138437
30negative regulation of erythrocyte differentiation (GO:0045647)3.64686873
31regulation of ARF protein signal transduction (GO:0032012)3.59917745
32cellular potassium ion homeostasis (GO:0030007)3.58607515
33neuromuscular process controlling balance (GO:0050885)3.56949062
34cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.54937146
35G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.53035710
36cytoskeletal anchoring at plasma membrane (GO:0007016)3.53028499
37regulation of dendritic spine morphogenesis (GO:0061001)3.50917659
38membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.45362780
39neuronal action potential propagation (GO:0019227)3.41358740
40long-term memory (GO:0007616)3.40565633
41regulation of early endosome to late endosome transport (GO:2000641)3.40177058
42cell communication by electrical coupling (GO:0010644)3.38087518
43protein localization to endosome (GO:0036010)3.37733028
44positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.36608027
45regulation of synapse maturation (GO:0090128)3.35506633
46positive regulation of synapse maturation (GO:0090129)3.34958422
47activation of Rac GTPase activity (GO:0032863)3.33019127
48synaptic transmission, glutamatergic (GO:0035249)3.30070454
49proline transport (GO:0015824)3.29783049
50peptidyl-tyrosine autophosphorylation (GO:0038083)3.28052958
51positive regulation of membrane potential (GO:0045838)3.26640245
52regulation of synaptic plasticity (GO:0048167)3.26207950
53regulation of mammary gland epithelial cell proliferation (GO:0033599)3.24117952
54membrane depolarization during action potential (GO:0086010)3.24070884
55cell-cell junction maintenance (GO:0045217)3.23833071
56negative regulation of inclusion body assembly (GO:0090084)3.22195825
57neuronal ion channel clustering (GO:0045161)3.15572944
58regulation of excitatory postsynaptic membrane potential (GO:0060079)3.12974790
59negative regulation of organelle assembly (GO:1902116)3.11514081
60fusion of sperm to egg plasma membrane (GO:0007342)3.09300076
61glycine transport (GO:0015816)3.08849084
62protein targeting to plasma membrane (GO:0072661)3.08090343
63dendritic spine organization (GO:0097061)3.08086083
64adherens junction assembly (GO:0034333)3.06757880
65neurotransmitter-gated ion channel clustering (GO:0072578)3.05171316
66prepulse inhibition (GO:0060134)3.01755241
67vesicle transport along microtubule (GO:0047496)3.01456748
68negative regulation of dendrite morphogenesis (GO:0050774)2.99851058
69dopamine receptor signaling pathway (GO:0007212)2.99317260
70synaptic vesicle endocytosis (GO:0048488)2.99305473
71acrosome assembly (GO:0001675)2.98646556
72cerebellar Purkinje cell layer development (GO:0021680)2.98195010
73auditory behavior (GO:0031223)2.97990756
74protein retention in ER lumen (GO:0006621)2.97634312
75positive regulation of protein dephosphorylation (GO:0035307)2.97287226
76plasma membrane fusion (GO:0045026)2.96028549
77regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.96027020
78potassium ion homeostasis (GO:0055075)2.95443534
79regulation of clathrin-mediated endocytosis (GO:2000369)2.94452651
80gamma-aminobutyric acid transport (GO:0015812)2.93835728
81neuron-neuron synaptic transmission (GO:0007270)2.91820927
82regulation of postsynaptic membrane potential (GO:0060078)2.90806380
83glutamate receptor signaling pathway (GO:0007215)2.90558358
84negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.90539476
85neuromuscular process controlling posture (GO:0050884)2.90233749
86neurotransmitter transport (GO:0006836)2.88692848
87signal complex assembly (GO:0007172)2.87848065
88cell-substrate adherens junction assembly (GO:0007045)2.87133043
89focal adhesion assembly (GO:0048041)2.87133043
90semaphorin-plexin signaling pathway (GO:0071526)2.86392207
91L-amino acid import (GO:0043092)2.85095007
92positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.84489714
93dendrite morphogenesis (GO:0048813)2.84062544
94positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.83759635
95response to auditory stimulus (GO:0010996)2.82631359
96potassium ion import (GO:0010107)2.82233361
97establishment of nucleus localization (GO:0040023)2.78941994
98cAMP biosynthetic process (GO:0006171)2.78711158
99regulation of neurotransmitter secretion (GO:0046928)2.78457270
100positive regulation of fibroblast migration (GO:0010763)2.75103713
101regulation of dendritic spine development (GO:0060998)2.75088770
102mating behavior (GO:0007617)2.74568365
103cerebellar Purkinje cell differentiation (GO:0021702)2.72586981
104positive regulation of neurotransmitter transport (GO:0051590)2.72471024
105membrane depolarization (GO:0051899)2.72256538
106positive regulation of Rap GTPase activity (GO:0032854)2.72201063
107positive regulation of dendritic spine development (GO:0060999)2.71409688
108maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.70154880
109positive regulation of synaptic transmission, GABAergic (GO:0032230)2.69550515
110positive regulation of neurotransmitter secretion (GO:0001956)2.69514729
111neuromuscular process (GO:0050905)2.69438036
112regulation of neurotransmitter levels (GO:0001505)2.63784798
113cellular sodium ion homeostasis (GO:0006883)2.63650117
114regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.63375406
115* regulation of ARF GTPase activity (GO:0032312)2.62997982
116myelin maintenance (GO:0043217)2.62730466
117stress fiber assembly (GO:0043149)2.61688991
118chemosensory behavior (GO:0007635)2.60208236
119nerve growth factor signaling pathway (GO:0038180)2.59671030
120apoptotic process involved in morphogenesis (GO:0060561)2.58830134
121negative regulation of cell size (GO:0045792)2.58322090
122long-term synaptic potentiation (GO:0060291)2.57237844
123regulation of neurotransmitter transport (GO:0051588)2.56309521
124cell migration in hindbrain (GO:0021535)2.56241919
125regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.55558487
126response to parathyroid hormone (GO:0071107)2.53521685
127regulation of synaptic transmission, glutamatergic (GO:0051966)2.53322916
128cell communication involved in cardiac conduction (GO:0086065)2.53187173
129transmission of nerve impulse (GO:0019226)2.53063397
130regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.52387261
131positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.52387261
132establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.51961478
133mitochondrion transport along microtubule (GO:0047497)2.51961478
134regulation of vesicle fusion (GO:0031338)2.50622779
135positive regulation of dendritic spine morphogenesis (GO:0061003)2.49591131
136adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.49545019
137establishment of mitochondrion localization (GO:0051654)2.46839325
138barbed-end actin filament capping (GO:0051016)2.43874886
139regulation of voltage-gated calcium channel activity (GO:1901385)2.43777746
140positive regulation of dendrite development (GO:1900006)2.43553938
141negative regulation of microtubule polymerization (GO:0031115)2.43289138
142retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.42059886
143regulation of NFAT protein import into nucleus (GO:0051532)2.40588985
144regulation of protein dephosphorylation (GO:0035304)2.39914121
145cellular response to catecholamine stimulus (GO:0071870)2.38433367
146cellular response to monoamine stimulus (GO:0071868)2.38433367
147receptor recycling (GO:0001881)2.38040262
148mannose metabolic process (GO:0006013)2.37901108

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.79246070
2* RARB_27405468_Chip-Seq_BRAIN_Mouse3.05169978
3* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.99252768
4DROSHA_22980978_ChIP-Seq_HELA_Human2.76289284
5MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.67263569
6* REST_21632747_ChIP-Seq_MESCs_Mouse2.54701821
7TP63_17297297_ChIP-ChIP_HaCaT_Human2.34980503
8VDR_21846776_ChIP-Seq_THP-1_Human2.25203572
9* ELK3_25401928_ChIP-Seq_HUVEC_Human2.21850912
10MYC_22102868_ChIP-Seq_BL_Human2.21754994
11* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.17850048
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.11633890
13SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10858131
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.10476051
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.09353758
16* RACK7_27058665_Chip-Seq_MCF-7_Human2.09073512
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.08160202
18* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.07650474
19RNF2_18974828_ChIP-Seq_MESCs_Mouse2.04188207
20EZH2_18974828_ChIP-Seq_MESCs_Mouse2.04188207
21* REST_18959480_ChIP-ChIP_MESCs_Mouse2.03847568
22STAT6_21828071_ChIP-Seq_BEAS2B_Human2.02459735
23SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.00502850
24TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.99974554
25JARID2_20064375_ChIP-Seq_MESCs_Mouse1.99586716
26EZH2_27294783_Chip-Seq_ESCs_Mouse1.99046798
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.96454324
28* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.93958935
29KDM2B_26808549_Chip-Seq_K562_Human1.91215497
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.90648580
31JARID2_20075857_ChIP-Seq_MESCs_Mouse1.88041366
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.82887067
33* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.80944043
34* TET1_21451524_ChIP-Seq_MESCs_Mouse1.70701206
35* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.69405647
36* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.68179678
37* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.66811295
38SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.65802520
39SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.63576932
40EZH2_27304074_Chip-Seq_ESCs_Mouse1.63159942
41NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.63159690
42* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.62616466
43SRY_22984422_ChIP-ChIP_TESTIS_Rat1.60709664
44SA1_27219007_Chip-Seq_ERYTHROID_Human1.56247785
45CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.55419517
46* KDM2B_26808549_Chip-Seq_DND41_Human1.54917241
47* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.53212641
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.53199312
49TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.51101928
50* LXR_22292898_ChIP-Seq_THP-1_Human1.50952850
51* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.49130957
52SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.49056491
53GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.48829701
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.47261890
55* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.42265003
56CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.40064460
57SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.38059915
58* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.34796800
59* RING1B_27294783_Chip-Seq_ESCs_Mouse1.34437328
60* CTCF_27219007_Chip-Seq_Bcells_Human1.34345299
61PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.33205092
62* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.33090433
63SMC4_20622854_ChIP-Seq_HELA_Human1.31670820
64ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.30208861
65RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.29817145
66GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.29772779
67ZNF274_21170338_ChIP-Seq_K562_Hela1.26691825
68DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.26572676
69TET1_21490601_ChIP-Seq_MESCs_Mouse1.24348445
70KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.23421988
71TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.23144799
72CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.22089750
73KDM2B_26808549_Chip-Seq_JURKAT_Human1.21582732
74* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.21173489
75RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20913385
76* TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.20523099
77GATA1_26923725_Chip-Seq_HPCs_Mouse1.18959659
78KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16708677
79NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.15405235
80KLF4_19829295_ChIP-Seq_ESCs_Human1.15128787
81EED_16625203_ChIP-ChIP_MESCs_Mouse1.12839710
82GBX2_23144817_ChIP-Seq_PC3_Human1.12820696
83SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12425979
84ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.12344920
85OCT4_19829295_ChIP-Seq_ESCs_Human1.11434889
86ZNF263_19887448_ChIP-Seq_K562_Human1.11197611
87MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.11153620
88E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10641598
89THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.10490314
90* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10335218
91VDR_24763502_ChIP-Seq_THP-1_Human1.09918637
92* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.08946231
93SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.07991571
94MAF_26560356_Chip-Seq_TH2_Human1.07007386
95BCOR_27268052_Chip-Seq_Bcells_Human1.06864762
96PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.06713948
97SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.06160801
98KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.05746943
99* TCF7_22412390_ChIP-Seq_EML_Mouse1.05552146
100CREB1_26743006_Chip-Seq_LNCaP_Human1.04998906
101AR_19668381_ChIP-Seq_PC3_Human1.04650719
102TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.04428112
103TP53_22127205_ChIP-Seq_IMR90_Human1.03674781
104* RING1B_27294783_Chip-Seq_NPCs_Mouse1.03460814
105GATA1_19941827_ChIP-Seq_MEL_Mouse1.03366698
106MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02843317
107ELK4_26923725_Chip-Seq_MESODERM_Mouse1.01892178
108* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.00395365
109* KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.98728701
110SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.97928921
111P68_20966046_ChIP-Seq_HELA_Human0.97269622
112SMAD3_21741376_ChIP-Seq_ESCs_Human0.96523431
113WDR5_24793694_ChIP-Seq_LNCAP_Human0.94167268
114SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92605077
115TP53_23651856_ChIP-Seq_MEFs_Mouse0.89391680
116MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.88550651
117* TP63_22573176_ChIP-Seq_HFKS_Human0.88365012
118ELF1_20517297_ChIP-Seq_JURKAT_Human0.88362566
119SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87217788
120SOX2_21211035_ChIP-Seq_LN229_Gbm0.86992016
121SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.86546784
122DPY_21335234_ChIP-Seq_ESCs_Mouse0.85305750
123SMAD3_21741376_ChIP-Seq_HESCs_Human0.85152934
124VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.83871199
125P300_27058665_Chip-Seq_ZR-75-30cells_Human0.82589107
126* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.81810218
127SMAD4_21741376_ChIP-Seq_ESCs_Human0.81445861
128EP300_21415370_ChIP-Seq_HL-1_Mouse0.80656230
129FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80487325
130ESR2_21235772_ChIP-Seq_MCF-7_Human0.80475295
131YAP1_20516196_ChIP-Seq_MESCs_Mouse0.79878704
132* MYC_27129775_Chip-Seq_CORNEA_Mouse0.79211714
133SMAD4_21799915_ChIP-Seq_A2780_Human0.78863677
134CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.78529560
135RUNX1_27514584_Chip-Seq_MCF-7_Human0.78409304

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.31545818
2MP0005410_abnormal_fertilization4.12546666
3MP0003635_abnormal_synaptic_transmissio3.91715940
4MP0004270_analgesia3.59093967
5MP0003880_abnormal_central_pattern3.34076614
6MP0002822_catalepsy3.29243157
7* MP0002063_abnormal_learning/memory/cond3.03970939
8MP0009745_abnormal_behavioral_response2.85265173
9MP0002064_seizures2.71826331
10MP0005409_darkened_coat_color2.58877062
11MP0009046_muscle_twitch2.53269146
12MP0005423_abnormal_somatic_nervous2.31410095
13MP0004858_abnormal_nervous_system2.28986302
14* MP0002572_abnormal_emotion/affect_behav2.22368857
15MP0009780_abnormal_chondrocyte_physiolo2.13105783
16MP0001486_abnormal_startle_reflex2.12169623
17MP0001968_abnormal_touch/_nociception2.11989417
18MP0002272_abnormal_nervous_system2.03841423
19MP0005623_abnormal_meninges_morphology2.01101225
20MP0002734_abnormal_mechanical_nocicepti2.00871437
21MP0008569_lethality_at_weaning2.00590726
22MP0002909_abnormal_adrenal_gland1.98041270
23MP0004811_abnormal_neuron_physiology1.94188885
24MP0003329_amyloid_beta_deposits1.86365128
25MP0000751_myopathy1.82449348
26MP0008961_abnormal_basal_metabolism1.81533681
27MP0008260_abnormal_autophagy1.78251396
28MP0002877_abnormal_melanocyte_morpholog1.76024518
29MP0001501_abnormal_sleep_pattern1.59034503
30MP0003283_abnormal_digestive_organ1.58432662
31MP0003698_abnormal_male_reproductive1.58230368
32MP0002249_abnormal_larynx_morphology1.58110452
33MP0005058_abnormal_lysosome_morphology1.56753142
34MP0000678_abnormal_parathyroid_gland1.55995662
35MP0004233_abnormal_muscle_weight1.55934278
36MP0004885_abnormal_endolymph1.55102581
37MP0001440_abnormal_grooming_behavior1.54454979
38MP0003879_abnormal_hair_cell1.51371884
39MP0000955_abnormal_spinal_cord1.46401555
40MP0002733_abnormal_thermal_nociception1.45550282
41MP0002653_abnormal_ependyma_morphology1.45087396
42MP0005167_abnormal_blood-brain_barrier1.44441539
43MP0001970_abnormal_pain_threshold1.44383162
44MP0002736_abnormal_nociception_after1.43336792
45MP0003633_abnormal_nervous_system1.41482977
46MP0003787_abnormal_imprinting1.36386978
47MP0004185_abnormal_adipocyte_glucose1.32610648
48MP0002557_abnormal_social/conspecific_i1.30360340
49MP0004381_abnormal_hair_follicle1.29755213
50MP0002067_abnormal_sensory_capabilities1.28070740
51MP0000778_abnormal_nervous_system1.26650550
52MP0003075_altered_response_to1.26582908
53MP0003566_abnormal_cell_adhesion1.25615697
54MP0000569_abnormal_digit_pigmentation1.24184938
55MP0002066_abnormal_motor_capabilities/c1.23005258
56MP0002184_abnormal_innervation1.22394999
57MP0004924_abnormal_behavior1.21715691
58MP0005386_behavior/neurological_phenoty1.21715691
59* MP0002882_abnormal_neuron_morphology1.19638671
60MP0005666_abnormal_adipose_tissue1.19251126
61MP0005451_abnormal_body_composition1.19228144
62MP0002735_abnormal_chemical_nociception1.17290987
63MP0003631_nervous_system_phenotype1.16853565
64MP0003453_abnormal_keratinocyte_physiol1.15362830
65MP0002152_abnormal_brain_morphology1.14260095
66MP0004510_myositis1.14060615
67MP0003646_muscle_fatigue1.11681843
68MP0003091_abnormal_cell_migration1.07893552
69MP0008877_abnormal_DNA_methylation1.07335329
70MP0005375_adipose_tissue_phenotype1.06225673
71MP0000579_abnormal_nail_morphology1.05874953
72MP0001929_abnormal_gametogenesis1.05751810
73MP0009278_abnormal_bone_marrow1.05664331
74MP0000537_abnormal_urethra_morphology1.05327125
75MP0001346_abnormal_lacrimal_gland1.04171833
76MP0010234_abnormal_vibrissa_follicle1.03966765
77MP0005670_abnormal_white_adipose1.00880272
78MP0000681_abnormal_thyroid_gland1.00130838
79MP0002796_impaired_skin_barrier0.99935388
80MP0005171_absent_coat_pigmentation0.97425548
81MP0004145_abnormal_muscle_electrophysio0.96049800
82MP0004085_abnormal_heartbeat0.93648685
83MP0000013_abnormal_adipose_tissue0.92690677
84MP0003705_abnormal_hypodermis_morpholog0.90797697
85MP0003122_maternal_imprinting0.88686701
86MP0002161_abnormal_fertility/fecundity0.88055247
87MP0008874_decreased_physiological_sensi0.87934085
88MP0003634_abnormal_glial_cell0.87743309
89MP0005646_abnormal_pituitary_gland0.86665698
90MP0009672_abnormal_birth_weight0.84685530
91MP0002234_abnormal_pharynx_morphology0.83546118
92MP0004130_abnormal_muscle_cell0.83417310
93MP0000920_abnormal_myelination0.82974511
94MP0004087_abnormal_muscle_fiber0.81643997
95MP0000534_abnormal_ureter_morphology0.80973795
96MP0000733_abnormal_muscle_development0.80502349
97MP0000747_muscle_weakness0.79670015
98MP0003632_abnormal_nervous_system0.79088556
99MP0003191_abnormal_cellular_cholesterol0.77809448
100MP0004084_abnormal_cardiac_muscle0.77401058
101MP0002069_abnormal_eating/drinking_beha0.75738879
102MP0003137_abnormal_impulse_conducting0.75350340
103MP0003861_abnormal_nervous_system0.75320463
104MP0004036_abnormal_muscle_relaxation0.75314203
105MP0001177_atelectasis0.74735533
106MP0003279_aneurysm0.74410456
107MP0001984_abnormal_olfaction0.73757905
108MP0003172_abnormal_lysosome_physiology0.73393738
109MP0003690_abnormal_glial_cell0.72703435
110MP0003300_gastrointestinal_ulcer0.72674260
111MP0004484_altered_response_of0.72515892
112MP0004215_abnormal_myocardial_fiber0.72372652
113MP0000759_abnormal_skeletal_muscle0.72361397
114MP0003045_fibrosis0.71684376
115MP0000003_abnormal_adipose_tissue0.70503301
116MP0000604_amyloidosis0.69823187
117MP0005621_abnormal_cell_physiology0.69700907
118MP0008872_abnormal_physiological_respon0.69402943
119MP0001502_abnormal_circadian_rhythm0.69277622
120MP0002269_muscular_atrophy0.69023449
121MP0003123_paternal_imprinting0.68213358
122MP0005501_abnormal_skin_physiology0.67886601
123MP0004947_skin_inflammation0.67730931
124MP0002089_abnormal_postnatal_growth/wei0.67323816
125MP0000566_synostosis0.67027592
126MP0002229_neurodegeneration0.66479175
127MP0003183_abnormal_peptide_metabolism0.63789182
128MP0002837_dystrophic_cardiac_calcinosis0.62875635
129MP0001348_abnormal_lacrimal_gland0.61292586
130MP0001958_emphysema0.61194908
131MP0001849_ear_inflammation0.61166518
132MP0001765_abnormal_ion_homeostasis0.60188788
133MP0005076_abnormal_cell_differentiation0.59405376
134MP0003303_peritoneal_inflammation0.59167256
135MP0000015_abnormal_ear_pigmentation0.58493723

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.19340675
2Focal motor seizures (HP:0011153)4.75914862
3Absent/shortened dynein arms (HP:0200106)4.07085927
4Dynein arm defect of respiratory motile cilia (HP:0012255)4.07085927
5Focal seizures (HP:0007359)4.05848900
6Visual hallucinations (HP:0002367)4.03613737
7Abnormality of the lower motor neuron (HP:0002366)3.82247450
8Ankle clonus (HP:0011448)3.52705014
9Supranuclear gaze palsy (HP:0000605)3.39578645
10Action tremor (HP:0002345)3.34612779
11Bundle branch block (HP:0011710)3.34064058
12Impaired vibration sensation in the lower limbs (HP:0002166)3.24351896
13Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.12384456
14Ventricular fibrillation (HP:0001663)3.06752162
15Peripheral hypomyelination (HP:0007182)3.04570047
16Postural instability (HP:0002172)2.95471779
17Annular pancreas (HP:0001734)2.93626816
18Progressive cerebellar ataxia (HP:0002073)2.92356042
19Depression (HP:0000716)2.90191266
20Insomnia (HP:0100785)2.87439505
21Epileptic encephalopathy (HP:0200134)2.84097255
22Urinary urgency (HP:0000012)2.83128517
23Papilledema (HP:0001085)2.82839328
24Urinary bladder sphincter dysfunction (HP:0002839)2.81793263
25Dysmetric saccades (HP:0000641)2.78560640
26Pointed chin (HP:0000307)2.76833798
27Hyperacusis (HP:0010780)2.68091361
28Cerebral aneurysm (HP:0004944)2.62296180
29Poor eye contact (HP:0000817)2.61593599
30Cerebral inclusion bodies (HP:0100314)2.55847365
31Atonic seizures (HP:0010819)2.55590756
32Broad face (HP:0000283)2.53311109
33Dysdiadochokinesis (HP:0002075)2.52852799
34Upper limb amyotrophy (HP:0009129)2.51681456
35Distal upper limb amyotrophy (HP:0007149)2.51681456
36Abnormal social behavior (HP:0012433)2.49947249
37Impaired social interactions (HP:0000735)2.49947249
38Dysmetria (HP:0001310)2.47263436
39Infertility (HP:0000789)2.47084783
40Impaired smooth pursuit (HP:0007772)2.46129664
41Hemiplegia (HP:0002301)2.43079347
42Shallow orbits (HP:0000586)2.40259944
43Generalized tonic-clonic seizures (HP:0002069)2.38851522
44Genetic anticipation (HP:0003743)2.37784303
45Hemiparesis (HP:0001269)2.37667503
46Gaze-evoked nystagmus (HP:0000640)2.37281672
47Male infertility (HP:0003251)2.36329569
48Absence seizures (HP:0002121)2.36214947
49Mutism (HP:0002300)2.33774045
50Neurofibrillary tangles (HP:0002185)2.33771285
51Distal lower limb amyotrophy (HP:0008944)2.33339135
52Abnormal respiratory motile cilium physiology (HP:0012261)2.30988215
53Abnormality of ocular smooth pursuit (HP:0000617)2.29337204
54Tetraplegia (HP:0002445)2.29166138
55Termporal pattern (HP:0011008)2.27521844
56Insidious onset (HP:0003587)2.27521844
57Rapidly progressive (HP:0003678)2.25473809
58Neoplasm of the heart (HP:0100544)2.25258642
59Megalencephaly (HP:0001355)2.24639516
60Spastic gait (HP:0002064)2.24163727
61Turricephaly (HP:0000262)2.23536825
62Abnormal respiratory epithelium morphology (HP:0012253)2.23402139
63Abnormal respiratory motile cilium morphology (HP:0005938)2.23402139
64Torticollis (HP:0000473)2.23345774
65Intention tremor (HP:0002080)2.22457597
66Resting tremor (HP:0002322)2.20203798
67Lower limb amyotrophy (HP:0007210)2.18749264
68Akinesia (HP:0002304)2.16918650
69Stridor (HP:0010307)2.15899320
70Amblyopia (HP:0000646)2.15763579
71Elfin facies (HP:0004428)2.14961413
72Abnormal eating behavior (HP:0100738)2.14898745
73Amyotrophic lateral sclerosis (HP:0007354)2.14766900
74Febrile seizures (HP:0002373)2.14436693
75Truncus arteriosus (HP:0001660)2.14315092
76Ankyloglossia (HP:0010296)2.13626427
77Ulnar bowing (HP:0003031)2.13454596
78Hyperparathyroidism (HP:0000843)2.12886611
79Spastic tetraparesis (HP:0001285)2.11582226
80Impaired vibratory sensation (HP:0002495)2.11031086
81Difficulty running (HP:0009046)2.10241377
82Truncal ataxia (HP:0002078)2.09259075
83Dialeptic seizures (HP:0011146)2.09184433
84Bowel incontinence (HP:0002607)2.09044262
85Bradykinesia (HP:0002067)2.08503519
86Lower limb muscle weakness (HP:0007340)2.07118197
87Spinal canal stenosis (HP:0003416)2.04903387
88Neuronal loss in central nervous system (HP:0002529)2.04751830
89Stereotypic behavior (HP:0000733)2.04112219
90Overriding aorta (HP:0002623)2.03514221
91Centrally nucleated skeletal muscle fibers (HP:0003687)2.02653224
92Distal lower limb muscle weakness (HP:0009053)2.01963789
93Polygenic inheritance (HP:0010982)2.01067265
94Obstructive sleep apnea (HP:0002870)2.00093542
95Slow saccadic eye movements (HP:0000514)1.99959444
96Achilles tendon contracture (HP:0001771)1.99651986
97Anxiety (HP:0000739)1.99150729
98Growth hormone excess (HP:0000845)1.98914407
99Focal dystonia (HP:0004373)1.98854355
100Protrusio acetabuli (HP:0003179)1.98748805
101Hand muscle atrophy (HP:0009130)1.98227292
102Bronchomalacia (HP:0002780)1.98185021
103Sudden death (HP:0001699)1.97172921
104Apathy (HP:0000741)1.97165236
105Broad-based gait (HP:0002136)1.96105809
106Long palpebral fissure (HP:0000637)1.95397229
107Difficulty climbing stairs (HP:0003551)1.95137771
108Intellectual disability, profound (HP:0002187)1.94352243
109Rhinitis (HP:0012384)1.93902885
110Distal sensory impairment (HP:0002936)1.91504848
111Hyperthyroidism (HP:0000836)1.91261175
112Abnormal large intestine physiology (HP:0012700)1.91091998
113Foot dorsiflexor weakness (HP:0009027)1.88924657
114Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.87373300
115Mitral regurgitation (HP:0001653)1.87173917
116Abnormality of the Achilles tendon (HP:0005109)1.85779289
117Renovascular hypertension (HP:0100817)1.85139541
118Rigidity (HP:0002063)1.84440553
119Clonus (HP:0002169)1.84108942
120Lower limb asymmetry (HP:0100559)1.83803181
121Heart block (HP:0012722)1.83236005
122Exercise-induced myalgia (HP:0003738)1.83009911
123Decreased motor nerve conduction velocity (HP:0003431)1.81413084
124Spinal cord compression (HP:0002176)1.79789485
125Abnormality of binocular vision (HP:0011514)1.79778160
126Diplopia (HP:0000651)1.79778160
127Hypercortisolism (HP:0001578)1.79319864
128Vertebral compression fractures (HP:0002953)1.79301878
129Abnormality of saccadic eye movements (HP:0000570)1.79080949
130Ocular albinism (HP:0001107)1.77795324
131Renal duplication (HP:0000075)1.77781709
132Nuclear cataract (HP:0100018)1.74281194
133Onion bulb formation (HP:0003383)1.73191671
134Abnormal EKG (HP:0003115)1.72786498
135Chronic bronchitis (HP:0004469)1.72404180
136Aplasia involving bones of the upper limbs (HP:0009823)1.72351350
137Aplasia of the phalanges of the hand (HP:0009802)1.72351350
138Aplasia involving bones of the extremities (HP:0009825)1.72351350
139Deep palmar crease (HP:0006191)1.71920195
140Craniofacial dystonia (HP:0012179)1.71369759
141Diminished motivation (HP:0000745)1.70394245
142Hammertoe (HP:0001765)1.69261211
143Patellar dislocation (HP:0002999)1.68972873
144Axonal loss (HP:0003447)1.68967850
145Disproportionate tall stature (HP:0001519)1.67879684
146Increased variability in muscle fiber diameter (HP:0003557)1.67741980
147Precocious puberty (HP:0000826)1.66320463
148Scanning speech (HP:0002168)1.65980432
149Arnold-Chiari malformation (HP:0002308)1.62987770
150Abnormality of the foot musculature (HP:0001436)1.62449340
151Sleep apnea (HP:0010535)1.61634203
152Broad distal phalanx of finger (HP:0009836)1.61546522
153Abnormality of oral frenula (HP:0000190)1.59574619
154Increased connective tissue (HP:0009025)1.58264767
155Germ cell neoplasia (HP:0100728)1.58110219

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA43.90114474
2MAP3K93.68114537
3NTRK33.25896166
4SMG13.05705695
5ICK2.75741365
6PAK62.52318398
7DAPK22.48566443
8KSR22.41934608
9CAMKK12.37068053
10STK382.32474683
11TESK12.32391892
12PDK32.24777973
13PDK42.24777973
14TRIB32.21520870
15TYRO32.18527370
16MINK12.17067466
17SIK12.01156100
18MAP3K42.01066564
19MARK11.91825260
20CDK121.90421182
21ERN11.81736584
22TAOK11.77008311
23NTRK21.74125164
24RIPK11.65212572
25NTRK11.64689146
26PTK2B1.60675641
27ALK1.41235272
28IRAK31.39562480
29CDK51.37214682
30PKN21.34838134
31LMTK21.33319341
32SIK21.32041257
33DAPK11.26292497
34KSR11.18861708
35EEF2K1.18843772
36RIPK41.18798175
37PDK21.17696760
38MAP3K111.17099448
39MAP3K21.16540107
40PNCK1.13676311
41PDK11.12931260
42PRKCH1.12277911
43UHMK11.11785341
44LATS21.09737981
45STK111.08194630
46FGFR41.07996481
47MAP2K41.07613283
48DMPK1.07530365
49MAPK121.06651792
50RET1.01834617
51MARK21.00088691
52PDPK10.96965096
53NEK10.96741612
54CDK150.93524586
55TAOK20.93322233
56MAP3K100.92990177
57CAMK10.91978884
58MAP2K70.91675663
59CDK180.89411531
60PDGFRA0.87418947
61ARAF0.87238695
62CAMK1G0.87115433
63TTN0.86981787
64IRAK20.86870514
65PINK10.86783852
66EPHA20.86770472
67PHKG20.86630297
68PHKG10.86630297
69CAMK1D0.85048607
70BMX0.84378989
71PRKCG0.84329644
72CDK140.83995626
73CDK11A0.82344372
74MAP3K10.81838074
75BRAF0.79984553
76FES0.79004276
77PRPF4B0.78505667
78MAP3K70.77927286
79WNK10.77088055
80CDK190.75734616
81MAP2K30.70909292
82SCYL20.69739516
83HIPK20.68778784
84MST1R0.68568085
85PRKG20.68311939
86DDR20.67182060
87GRK50.67130656
88RAF10.66489148
89NME20.66273358
90MAP2K20.65958384
91WNK40.65242103
92MAP3K130.64904643
93BRSK10.63552145
94NEK60.62490895
95PAK30.62366482
96CDC42BPA0.61029346
97SIK30.60431447
98PTK60.60407855
99SGK30.59773602
100DAPK30.59710616
101EPHB10.58034628
102MAPK110.56862115
103MAP4K10.54770348
104CAMK2A0.53610416
105CAMK40.53258612
106SGK2230.53175653
107SGK4940.53175653
108PRKD20.52019220
109RPS6KA30.49447568
110ROCK20.48546610
111PLK20.48456340
112PAK40.47147955
113SGK10.46469457
114MAPK100.46274378
115MAP3K30.44506990
116LRRK20.43873380
117TNK20.43414986
118PRKCZ0.43363754
119RPS6KA20.43101448
120CAMK2G0.41958847
121MAP3K80.39932809
122FYN0.38952773
123MAPK130.37322433
124FER0.36945710
125PRKD10.36848657
126MTOR0.36563972
127PTK20.35219645
128CAMKK20.34842193
129STK390.33382911
130DYRK1B0.33099746
131MAPK80.32890008
132CAMK2B0.31538118
133PDGFRB0.30493958

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047212.63703393
2Olfactory transduction_Homo sapiens_hsa047402.52243611
3Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.52076247
4Long-term potentiation_Homo sapiens_hsa047202.50502452
5Circadian entrainment_Homo sapiens_hsa047132.29915695
6Amphetamine addiction_Homo sapiens_hsa050312.23360027
7Nicotine addiction_Homo sapiens_hsa050332.13304619
8Glutamatergic synapse_Homo sapiens_hsa047242.07069194
9Gastric acid secretion_Homo sapiens_hsa049711.95099992
10Salivary secretion_Homo sapiens_hsa049701.91928279
11Insulin secretion_Homo sapiens_hsa049111.91752550
12GABAergic synapse_Homo sapiens_hsa047271.91473961
13Morphine addiction_Homo sapiens_hsa050321.88414019
14Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.86571352
15Aldosterone synthesis and secretion_Homo sapiens_hsa049251.81969006
16Dopaminergic synapse_Homo sapiens_hsa047281.81589463
17Nitrogen metabolism_Homo sapiens_hsa009101.80492256
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.78126267
19Cholinergic synapse_Homo sapiens_hsa047251.70763371
20Oxytocin signaling pathway_Homo sapiens_hsa049211.61743495
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.58449708
22Renin secretion_Homo sapiens_hsa049241.53060229
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.48318258
24Estrogen signaling pathway_Homo sapiens_hsa049151.44330301
25Dorso-ventral axis formation_Homo sapiens_hsa043201.43026796
26Glioma_Homo sapiens_hsa052141.42967106
27Cocaine addiction_Homo sapiens_hsa050301.42749234
28GnRH signaling pathway_Homo sapiens_hsa049121.42593621
29Vitamin B6 metabolism_Homo sapiens_hsa007501.40963881
30Calcium signaling pathway_Homo sapiens_hsa040201.36099594
31Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.35623905
32Notch signaling pathway_Homo sapiens_hsa043301.34455471
33Gap junction_Homo sapiens_hsa045401.32851188
34Type II diabetes mellitus_Homo sapiens_hsa049301.29265134
35Prion diseases_Homo sapiens_hsa050201.29033007
36cAMP signaling pathway_Homo sapiens_hsa040241.23967109
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.23520022
38Oocyte meiosis_Homo sapiens_hsa041141.22646181
39Acute myeloid leukemia_Homo sapiens_hsa052211.21356675
40Long-term depression_Homo sapiens_hsa047301.20860425
41cGMP-PKG signaling pathway_Homo sapiens_hsa040221.20278505
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17878411
43VEGF signaling pathway_Homo sapiens_hsa043701.16594876
44Carbohydrate digestion and absorption_Homo sapiens_hsa049731.11366032
45Melanogenesis_Homo sapiens_hsa049161.08924387
46ErbB signaling pathway_Homo sapiens_hsa040121.08800904
47Taste transduction_Homo sapiens_hsa047421.05697363
48Phospholipase D signaling pathway_Homo sapiens_hsa040721.03857324
49Dilated cardiomyopathy_Homo sapiens_hsa054141.03514823
50Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.02454595
51Glucagon signaling pathway_Homo sapiens_hsa049221.02098675
52Thyroid hormone signaling pathway_Homo sapiens_hsa049191.02038955
53mTOR signaling pathway_Homo sapiens_hsa041500.99862837
54Pancreatic cancer_Homo sapiens_hsa052120.99691645
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.98046072
56Axon guidance_Homo sapiens_hsa043600.97792716
57B cell receptor signaling pathway_Homo sapiens_hsa046620.97667553
58Neurotrophin signaling pathway_Homo sapiens_hsa047220.95796428
59Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.91089027
60Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.90296335
61Thyroid cancer_Homo sapiens_hsa052160.89190845
62Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.88054465
63Cardiac muscle contraction_Homo sapiens_hsa042600.88028637
64* Endocytosis_Homo sapiens_hsa041440.86754698
65Pancreatic secretion_Homo sapiens_hsa049720.85961768
66Thyroid hormone synthesis_Homo sapiens_hsa049180.85335222
67Serotonergic synapse_Homo sapiens_hsa047260.84701876
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83224052
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82914150
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80217049
71MAPK signaling pathway_Homo sapiens_hsa040100.79095268
72AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.79010275
73Non-small cell lung cancer_Homo sapiens_hsa052230.78707568
74Bladder cancer_Homo sapiens_hsa052190.77545101
75Rap1 signaling pathway_Homo sapiens_hsa040150.77215434
76Other glycan degradation_Homo sapiens_hsa005110.76143219
77Endometrial cancer_Homo sapiens_hsa052130.75969221
78Fatty acid biosynthesis_Homo sapiens_hsa000610.74296960
79Choline metabolism in cancer_Homo sapiens_hsa052310.73410951
80Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72797034
81Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71542280
82Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.69112060
83Renal cell carcinoma_Homo sapiens_hsa052110.68110542
84Prolactin signaling pathway_Homo sapiens_hsa049170.67466794
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.66905893
86Insulin signaling pathway_Homo sapiens_hsa049100.64073899
87Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64001758
88Inositol phosphate metabolism_Homo sapiens_hsa005620.63364307
89Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.62654938
90Leukocyte transendothelial migration_Homo sapiens_hsa046700.62586935
91Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62408701
92T cell receptor signaling pathway_Homo sapiens_hsa046600.60648698
93Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.60430859
94Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.60102839
95Glycosaminoglycan degradation_Homo sapiens_hsa005310.59603204
96Adherens junction_Homo sapiens_hsa045200.59354907
97Tight junction_Homo sapiens_hsa045300.58808421
98Ras signaling pathway_Homo sapiens_hsa040140.58518401
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.58458517
100Wnt signaling pathway_Homo sapiens_hsa043100.55701979
101Collecting duct acid secretion_Homo sapiens_hsa049660.55275015
102Pentose phosphate pathway_Homo sapiens_hsa000300.53341570
103Bile secretion_Homo sapiens_hsa049760.53077736
104Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.50738844
105MicroRNAs in cancer_Homo sapiens_hsa052060.49874715
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48929918
107Amoebiasis_Homo sapiens_hsa051460.48916729
108HIF-1 signaling pathway_Homo sapiens_hsa040660.48273035
109Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.47173085
110Alcoholism_Homo sapiens_hsa050340.46478026
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.46230971
112Proteoglycans in cancer_Homo sapiens_hsa052050.45880419
113Chronic myeloid leukemia_Homo sapiens_hsa052200.45065344
114Hedgehog signaling pathway_Homo sapiens_hsa043400.45013612
115Focal adhesion_Homo sapiens_hsa045100.44418783
116* Regulation of actin cytoskeleton_Homo sapiens_hsa048100.43763305
117Colorectal cancer_Homo sapiens_hsa052100.42206802
118AMPK signaling pathway_Homo sapiens_hsa041520.41958136
119Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41459902
120Platelet activation_Homo sapiens_hsa046110.41088083
121Hippo signaling pathway_Homo sapiens_hsa043900.40782134
122Vibrio cholerae infection_Homo sapiens_hsa051100.40518177

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