GIT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.60422995
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.92352337
3positive regulation of B cell differentiation (GO:0045579)4.30961405
4positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.23264022
5regulation of B cell receptor signaling pathway (GO:0050855)4.04750982
6detection of other organism (GO:0098543)3.90414192
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.89122994
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.89122994
9regulation of gamma-delta T cell differentiation (GO:0045586)3.88296526
10regulation of gamma-delta T cell activation (GO:0046643)3.79377300
11B cell receptor signaling pathway (GO:0050853)3.77324799
12regulation of B cell differentiation (GO:0045577)3.73758943
13detection of bacterium (GO:0016045)3.70953882
14mast cell activation (GO:0045576)3.69952964
15antigen processing and presentation of endogenous antigen (GO:0019883)3.69810369
16macrophage activation involved in immune response (GO:0002281)3.69627406
17negative regulation of granulocyte differentiation (GO:0030853)3.64864339
18negative regulation of phagocytosis (GO:0050765)3.58883829
19leukocyte aggregation (GO:0070486)3.57469291
20positive thymic T cell selection (GO:0045059)3.55376493
21regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.53412593
22neutrophil activation involved in immune response (GO:0002283)3.50226294
23negative regulation of lymphocyte mediated immunity (GO:0002707)3.46633370
24negative regulation of T cell mediated immunity (GO:0002710)3.40299517
25detection of external biotic stimulus (GO:0098581)3.39341162
26microglial cell activation (GO:0001774)3.33538955
27detection of molecule of bacterial origin (GO:0032490)3.32436240
28negative T cell selection (GO:0043383)3.31828604
29T cell homeostasis (GO:0043029)3.27633107
30neutrophil activation (GO:0042119)3.25121548
31definitive hemopoiesis (GO:0060216)3.25047805
32regulation of T cell tolerance induction (GO:0002664)3.24587167
33regulation of interleukin-12 biosynthetic process (GO:0045075)3.24203424
34macrophage activation (GO:0042116)3.21639063
35immunoglobulin mediated immune response (GO:0016064)3.21333642
36response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.21026603
37response to host immune response (GO:0052572)3.21026603
38activated T cell proliferation (GO:0050798)3.20404023
39interferon-gamma production (GO:0032609)3.19408416
40negative thymic T cell selection (GO:0045060)3.17736868
41positive regulation of isotype switching (GO:0045830)3.17242192
42regulation of regulatory T cell differentiation (GO:0045589)3.17069387
43regulation of tolerance induction (GO:0002643)3.16501084
44positive regulation of mast cell activation (GO:0033005)3.15590182
45negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.14906464
46negative regulation of cell killing (GO:0031342)3.14906464
47germinal center formation (GO:0002467)3.14649820
48megakaryocyte development (GO:0035855)3.13208860
49myeloid dendritic cell activation (GO:0001773)3.12106730
50negative regulation of leukocyte mediated immunity (GO:0002704)3.11982394
51positive T cell selection (GO:0043368)3.10383220
52response to host (GO:0075136)3.09877920
53response to host defenses (GO:0052200)3.09877920
54response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.09877920
55positive regulation of humoral immune response (GO:0002922)3.08651860
56negative regulation of interleukin-17 production (GO:0032700)3.07810217
57positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.07286270
58mature B cell differentiation (GO:0002335)3.06639028
59hepatocyte apoptotic process (GO:0097284)3.05679930
60positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.03714126
61positive regulation of granulocyte differentiation (GO:0030854)3.01805594
62modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.01175128
63positive regulation by organism of defense response of other organism involved in symbiotic interact3.01175128
64modulation by symbiont of host immune response (GO:0052553)3.01175128
65positive regulation by symbiont of host defense response (GO:0052509)3.01175128
66modulation by symbiont of host defense response (GO:0052031)3.01175128
67modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.01175128
68regulation of granulocyte differentiation (GO:0030852)3.01026575
69interferon-gamma-mediated signaling pathway (GO:0060333)3.00952003
70negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.00589936
71T cell migration (GO:0072678)2.98646051
72regulation of isotype switching to IgG isotypes (GO:0048302)2.98036528
73regulation of dendritic cell antigen processing and presentation (GO:0002604)2.96001503
74tolerance induction (GO:0002507)2.95954142
75regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.94642959
76B cell homeostasis (GO:0001782)2.94244744
77lymphocyte homeostasis (GO:0002260)2.93998910
78antigen receptor-mediated signaling pathway (GO:0050851)2.93823828
79mast cell activation involved in immune response (GO:0002279)2.93192009
80mast cell degranulation (GO:0043303)2.93192009
81T cell selection (GO:0045058)2.91762147
82defense response to protozoan (GO:0042832)2.91146994
83detection of biotic stimulus (GO:0009595)2.90473201
84cellular response to zinc ion (GO:0071294)2.89290531
85histone H3-K4 trimethylation (GO:0080182)2.87365425
86response to protozoan (GO:0001562)2.86689101
87granulocyte activation (GO:0036230)2.86065209
88response to muramyl dipeptide (GO:0032495)2.85740621
89regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.85142172
90regulation of myeloid leukocyte mediated immunity (GO:0002886)2.84908412
91NIK/NF-kappaB signaling (GO:0038061)2.83874911
92positive regulation of tolerance induction (GO:0002645)2.83541109
93positive regulation of DNA recombination (GO:0045911)2.83385976
94lymph node development (GO:0048535)2.83035811
95myeloid leukocyte mediated immunity (GO:0002444)2.82622619
96positive regulation of antigen processing and presentation (GO:0002579)2.82613579
97regulation of necroptotic process (GO:0060544)2.82222300
98response to interleukin-15 (GO:0070672)2.81465269
99regulation of hypersensitivity (GO:0002883)2.81447794
100thymic T cell selection (GO:0045061)2.79277683
101antigen processing and presentation via MHC class Ib (GO:0002475)2.78770086
102cellular extravasation (GO:0045123)2.78706402
103regulation of leukocyte degranulation (GO:0043300)2.77749249
104myeloid cell activation involved in immune response (GO:0002275)2.77289449
105positive regulation of mast cell degranulation (GO:0043306)2.76764408
106positive regulation of mast cell activation involved in immune response (GO:0033008)2.76764408
107mature B cell differentiation involved in immune response (GO:0002313)2.76744952
108regulation of T cell receptor signaling pathway (GO:0050856)2.75642079
109regulation of mast cell degranulation (GO:0043304)2.71177664
110negative regulation of erythrocyte differentiation (GO:0045647)2.67386670
111ribosomal small subunit assembly (GO:0000028)2.67240714
112leukocyte homeostasis (GO:0001776)2.66638012
113regulation of monocyte differentiation (GO:0045655)2.65497937
114regulation of alpha-beta T cell proliferation (GO:0046640)2.64733555
115cellular response to interleukin-15 (GO:0071350)2.64613601
116respiratory burst (GO:0045730)2.64476379
117T cell receptor signaling pathway (GO:0050852)2.62476723
118positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.60902646
119response to peptidoglycan (GO:0032494)2.60657629
120regulation of interferon-beta biosynthetic process (GO:0045357)2.60442915
121Arp2/3 complex-mediated actin nucleation (GO:0034314)2.60275277
122positive regulation of macrophage differentiation (GO:0045651)2.58460466
123dendritic cell chemotaxis (GO:0002407)2.57044274
124negative regulation of interleukin-12 production (GO:0032695)2.55457568
125myeloid dendritic cell differentiation (GO:0043011)2.54914560
126embryonic hemopoiesis (GO:0035162)2.54655130
127negative regulation of B cell proliferation (GO:0030889)2.54560251
128regulation of mast cell activation (GO:0033003)2.53978489
129dendritic cell migration (GO:0036336)2.53730461
130regulation of antigen processing and presentation (GO:0002577)2.53651136
131B cell mediated immunity (GO:0019724)2.53008915
132neutrophil mediated immunity (GO:0002446)2.52623954
133angiogenesis involved in wound healing (GO:0060055)2.51825511
134leukocyte degranulation (GO:0043299)2.51670298
135response to type I interferon (GO:0034340)2.50565602
136positive regulation of B cell activation (GO:0050871)2.50167744
137myeloid leukocyte activation (GO:0002274)2.49082862
138regulation of mast cell activation involved in immune response (GO:0033006)2.48678699

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.34399071
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.00060962
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.55032642
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.54857825
5SCL_19346495_ChIP-Seq_HPC-7_Human3.93092797
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.82125643
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.78051436
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.76852499
9BP1_19119308_ChIP-ChIP_Hs578T_Human3.41384017
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.22834051
11EGR1_19374776_ChIP-ChIP_THP-1_Human3.06265452
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.99491773
13IRF8_27001747_Chip-Seq_BMDM_Mouse2.85147082
14STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.82755074
15RUNX_20019798_ChIP-Seq_JUKART_Human2.70506014
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.70476720
17FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.61415034
18VDR_21846776_ChIP-Seq_THP-1_Human2.60691800
19MYC_22102868_ChIP-Seq_BL_Human2.60054305
20* SPI1_23547873_ChIP-Seq_NB4_Human2.56443414
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.51360039
22NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.50365776
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.49319921
24MYB_26560356_Chip-Seq_TH2_Human2.47454745
25STAT4_19710469_ChIP-ChIP_TH1__Mouse2.45266865
26IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.44278383
27MYB_26560356_Chip-Seq_TH1_Human2.21242342
28VDR_24763502_ChIP-Seq_THP-1_Human2.19336015
29FOXM1_23109430_ChIP-Seq_U2OS_Human2.10594677
30* MAF_26560356_Chip-Seq_TH1_Human2.10469519
31RUNX1_22412390_ChIP-Seq_EML_Mouse2.07285991
32FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.01080867
33SPI1_23127762_ChIP-Seq_K562_Human2.00835781
34MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.00763344
35ELF1_17652178_ChIP-ChIP_JURKAT_Human2.00513656
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.97980122
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.94604754
38UTX_26944678_Chip-Seq_JUKART_Human1.93573327
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.89521222
40LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.88121339
41BRD4_27068464_Chip-Seq_AML-cells_Mouse1.87271580
42VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77407684
43SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.75940193
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.75448180
45LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.73199113
46TCF7_22412390_ChIP-Seq_EML_Mouse1.71033107
47E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.59821246
48CIITA_25753668_ChIP-Seq_RAJI_Human1.55438000
49PU_27001747_Chip-Seq_BMDM_Mouse1.47307814
50SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.46690254
51CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.42986017
52GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.42305692
53FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.41657553
54GATA2_22383799_ChIP-Seq_G1ME_Mouse1.41488516
55* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.40910294
56NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.40848178
57Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.40438782
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.40152286
59ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36558217
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.36520360
61GATA3_27048872_Chip-Seq_THYMUS_Human1.36498010
62GATA1_19941826_ChIP-Seq_K562_Human1.35711025
63GATA1_22383799_ChIP-Seq_G1ME_Mouse1.35528108
64RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.29979308
65BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.27049820
66* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.25336110
67GATA1_22025678_ChIP-Seq_K562_Human1.23583227
68GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.20838317
69PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19249182
70* MAF_26560356_Chip-Seq_TH2_Human1.16341469
71KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.15485686
72GATA2_21666600_ChIP-Seq_HMVEC_Human1.15350861
73RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.14210047
74GATA1_19941827_ChIP-Seq_MEL_Mouse1.14014570
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.13922020
76CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12635057
77PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10516448
78TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.08527463
79KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07380081
80GATA2_19941826_ChIP-Seq_K562_Human1.05326614
81FOXP3_21729870_ChIP-Seq_TREG_Human1.03396104
82E2F1_21310950_ChIP-Seq_MCF-7_Human1.02816931
83VDR_24787735_ChIP-Seq_THP-1_Human1.02037376
84GATA3_26560356_Chip-Seq_TH2_Human0.99943739
85* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.99023988
86RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97883709
87NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.93718986
88CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91757775
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91746444
90KDM2B_26808549_Chip-Seq_DND41_Human0.91196246
91VDR_23849224_ChIP-Seq_CD4+_Human0.89528852
92VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.87667831
93SMRT_27268052_Chip-Seq_Bcells_Human0.87264823
94GATA1_19941827_ChIP-Seq_MEL86_Mouse0.86392730
95ETS1_22383799_ChIP-Seq_G1ME_Mouse0.86392188
96EZH2_22144423_ChIP-Seq_EOC_Human0.85526273
97TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.84873777
98RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83952514
99KDM2B_26808549_Chip-Seq_SUP-B15_Human0.82788923
100BCL6_27268052_Chip-Seq_Bcells_Human0.82332771
101HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.81198216
102KDM2B_26808549_Chip-Seq_JURKAT_Human0.80956248
103* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80651560
104ELK1_19687146_ChIP-ChIP_HELA_Human0.79761761
105STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.79042294
106PU.1_20513432_ChIP-Seq_Bcells_Mouse0.76249551
107ELK3_25401928_ChIP-Seq_HUVEC_Human0.76122527
108CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.75664041
109* SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.75614466
110GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75381354
111CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.73477900
112PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.73469223
113* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71468931
114IKZF1_21737484_ChIP-ChIP_HCT116_Human0.70330445
115SPI1_20517297_ChIP-Seq_HL60_Human0.69663399
116GATA3_26560356_Chip-Seq_TH1_Human0.68579547
117PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.67786905
118STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.66213632
119NCOR1_26117541_ChIP-Seq_K562_Human0.64774964

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.88957272
2MP0002396_abnormal_hematopoietic_system3.76294511
3MP0005671_abnormal_response_to3.25702662
4MP0000685_abnormal_immune_system2.91630946
5MP0003763_abnormal_thymus_physiology2.87004983
6MP0001800_abnormal_humoral_immune2.82934534
7MP0002452_abnormal_antigen_presenting2.57687730
8MP0005387_immune_system_phenotype2.56283399
9MP0001790_abnormal_immune_system2.56283399
10MP0005000_abnormal_immune_tolerance2.48037221
11* MP0002420_abnormal_adaptive_immunity2.46216269
12* MP0001819_abnormal_immune_cell2.44058956
13MP0002723_abnormal_immune_serum2.43398745
14* MP0002398_abnormal_bone_marrow2.43207183
15MP0009785_altered_susceptibility_to2.42206614
16MP0005464_abnormal_platelet_physiology2.40325761
17MP0002166_altered_tumor_susceptibility2.38333112
18MP0004808_abnormal_hematopoietic_stem2.37245408
19MP0002148_abnormal_hypersensitivity_rea2.34269370
20MP0005174_abnormal_tail_pigmentation2.33909907
21* MP0005025_abnormal_response_to2.31184235
22* MP0002419_abnormal_innate_immunity2.30449593
23MP0009278_abnormal_bone_marrow2.14530403
24* MP0000716_abnormal_immune_system2.10459629
25MP0003724_increased_susceptibility_to2.09267931
26MP0003436_decreased_susceptibility_to2.09266839
27* MP0000689_abnormal_spleen_morphology1.98785786
28MP0005397_hematopoietic_system_phenotyp1.96503478
29MP0001545_abnormal_hematopoietic_system1.96503478
30MP0008057_abnormal_DNA_replication1.95756035
31* MP0002722_abnormal_immune_system1.91585016
32MP0003303_peritoneal_inflammation1.89729573
33MP0002006_tumorigenesis1.89078743
34MP0000703_abnormal_thymus_morphology1.88225566
35* MP0002405_respiratory_system_inflammati1.86752655
36MP0000015_abnormal_ear_pigmentation1.83650899
37MP0009333_abnormal_splenocyte_physiolog1.83068323
38* MP0002429_abnormal_blood_cell1.79658906
39MP0000465_gastrointestinal_hemorrhage1.78032276
40MP0000569_abnormal_digit_pigmentation1.70194254
41MP0010155_abnormal_intestine_physiology1.69425460
42MP0001873_stomach_inflammation1.63732642
43MP0010094_abnormal_chromosome_stability1.61037553
44MP0005409_darkened_coat_color1.60050371
45MP0005075_abnormal_melanosome_morpholog1.58681927
46MP0008260_abnormal_autophagy1.55734382
47MP0006082_CNS_inflammation1.49419441
48MP0003300_gastrointestinal_ulcer1.49022486
49MP0002138_abnormal_hepatobiliary_system1.47883024
50MP0001853_heart_inflammation1.45374476
51MP0000490_abnormal_crypts_of1.45129565
52MP0002095_abnormal_skin_pigmentation1.40312038
53MP0002009_preneoplasia1.35976922
54MP0003866_abnormal_defecation1.35382795
55MP0004510_myositis1.34505417
56MP0001845_abnormal_inflammatory_respons1.34392583
57MP0003172_abnormal_lysosome_physiology1.31000899
58MP0000858_altered_metastatic_potential1.27927547
59MP0001958_emphysema1.27131705
60MP0008007_abnormal_cellular_replicative1.26139731
61MP0003828_pulmonary_edema1.25096354
62MP0002933_joint_inflammation1.23072685
63MP0001986_abnormal_taste_sensitivity1.19712923
64MP0005451_abnormal_body_composition1.19282864
65MP0004947_skin_inflammation1.17703551
66MP0008058_abnormal_DNA_repair1.16187693
67MP0003111_abnormal_nucleus_morphology1.15780865
68MP0003077_abnormal_cell_cycle1.13232823
69MP0004883_abnormal_blood_vessel1.07007540
70MP0003183_abnormal_peptide_metabolism1.06126649
71MP0003656_abnormal_erythrocyte_physiolo1.05338733
72MP0003448_altered_tumor_morphology1.04490894
73MP0001533_abnormal_skeleton_physiology1.03981171
74MP0005310_abnormal_salivary_gland0.99072103
75MP0002019_abnormal_tumor_incidence0.98356885
76MP0000604_amyloidosis0.94639160
77MP0002132_abnormal_respiratory_system0.93957337
78MP0001851_eye_inflammation0.93627573
79MP0005166_decreased_susceptibility_to0.92150650
80MP0005058_abnormal_lysosome_morphology0.90993894
81MP0005164_abnormal_response_to0.87852981
82MP0003075_altered_response_to0.87633282
83MP0000371_diluted_coat_color0.86956875
84MP0008469_abnormal_protein_level0.86915880
85MP0000343_altered_response_to0.85799528
86MP0002998_abnormal_bone_remodeling0.85395773
87MP0009840_abnormal_foam_cell0.85320330
88MP0004381_abnormal_hair_follicle0.84944204
89MP0003693_abnormal_embryo_hatching0.84188929
90MP0005390_skeleton_phenotype0.82254877
91MP0002075_abnormal_coat/hair_pigmentati0.80486322
92MP0003787_abnormal_imprinting0.77504760
93MP0003252_abnormal_bile_duct0.76962547
94MP0003279_aneurysm0.75936270
95MP0004130_abnormal_muscle_cell0.75768632
96MP0003690_abnormal_glial_cell0.75392067
97MP0010307_abnormal_tumor_latency0.73123756
98MP0000313_abnormal_cell_death0.72577718
99* MP0003091_abnormal_cell_migration0.70858918
100MP0001879_abnormal_lymphatic_vessel0.70789166
101MP0009764_decreased_sensitivity_to0.69883881
102MP0003943_abnormal_hepatobiliary_system0.69370258
103MP0006054_spinal_hemorrhage0.64891298
104MP0009765_abnormal_xenobiotic_induced0.64697239
105MP0008004_abnormal_stomach_pH0.63824909
106MP0001186_pigmentation_phenotype0.62825656
107MP0003045_fibrosis0.62781569
108MP0000767_abnormal_smooth_muscle0.62029560
109MP0000249_abnormal_blood_vessel0.61918235
110MP0003795_abnormal_bone_structure0.60919252
111MP0009115_abnormal_fat_cell0.60306846
112MP0001188_hyperpigmentation0.59947188
113MP0003566_abnormal_cell_adhesion0.58278161
114MP0009763_increased_sensitivity_to0.58026061
115MP0003191_abnormal_cellular_cholesterol0.57935445
116MP0005388_respiratory_system_phenotype0.57847669
117MP0002133_abnormal_respiratory_system0.57847669
118MP0008874_decreased_physiological_sensi0.57169592
119MP0008877_abnormal_DNA_methylation0.56115748
120MP0008995_early_reproductive_senescence0.54973339
121MP0004484_altered_response_of0.54852214
122MP0010352_gastrointestinal_tract_polyps0.54454607
123MP0002332_abnormal_exercise_endurance0.53805296
124MP0001663_abnormal_digestive_system0.53219136
125MP0003786_premature_aging0.53206931

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)4.63195754
2Panhypogammaglobulinemia (HP:0003139)4.31086128
3Recurrent viral infections (HP:0004429)4.20175036
4Recurrent bacterial skin infections (HP:0005406)4.15976143
5Recurrent fungal infections (HP:0002841)3.99770214
6Agammaglobulinemia (HP:0004432)3.81378310
7Abnormality of the fingertips (HP:0001211)3.69117229
8IgM deficiency (HP:0002850)3.65770893
9Elevated erythrocyte sedimentation rate (HP:0003565)3.61075401
10Eczematoid dermatitis (HP:0000976)3.57022284
11Myositis (HP:0100614)3.54667899
12Abnormal delayed hypersensitivity skin test (HP:0002963)3.54108121
13Recurrent gram-negative bacterial infections (HP:0005420)3.53807792
14Thyroiditis (HP:0100646)3.46719267
15Meningitis (HP:0001287)3.44909665
16Gastrointestinal infarctions (HP:0005244)3.43989645
17B lymphocytopenia (HP:0010976)3.42328923
18Abnormality of B cell number (HP:0010975)3.42328923
19Chronic otitis media (HP:0000389)3.42063307
20Cellulitis (HP:0100658)3.33762971
21Thrombocytosis (HP:0001894)3.27019676
22Prolonged bleeding time (HP:0003010)3.20957675
23Recurrent cutaneous fungal infections (HP:0011370)3.15095661
24Chronic mucocutaneous candidiasis (HP:0002728)3.15095661
25Eosinophilia (HP:0001880)3.13558338
26T lymphocytopenia (HP:0005403)3.05122897
27Spontaneous hematomas (HP:0007420)3.03912059
28Recurrent skin infections (HP:0001581)3.03511791
29Mediastinal lymphadenopathy (HP:0100721)2.97505374
30Abnormality of T cell number (HP:0011839)2.97260805
31Chromsome breakage (HP:0040012)2.94076843
32Granulocytopenia (HP:0001913)2.93804681
33Petechiae (HP:0000967)2.91560392
34Obstructive lung disease (HP:0006536)2.90158293
35Chronic obstructive pulmonary disease (HP:0006510)2.90158293
36Increased IgE level (HP:0003212)2.88748670
37Autoimmune hemolytic anemia (HP:0001890)2.86556425
38Severe combined immunodeficiency (HP:0004430)2.84465082
39Chromosomal breakage induced by crosslinking agents (HP:0003221)2.83388479
40Urticaria (HP:0001025)2.79703004
41Abnormality of T cells (HP:0002843)2.78771016
42Abnormality of eosinophils (HP:0001879)2.78199472
43Inflammation of the large intestine (HP:0002037)2.77884908
44Leukocytosis (HP:0001974)2.76986188
45Recurrent bronchitis (HP:0002837)2.75433995
46Stomatitis (HP:0010280)2.72289392
47IgG deficiency (HP:0004315)2.71413077
48Vasculitis (HP:0002633)2.66665570
49Gastrointestinal inflammation (HP:0004386)2.64399583
50Keratoconjunctivitis (HP:0001096)2.62255517
51Retrobulbar optic neuritis (HP:0100654)2.61853250
52Optic neuritis (HP:0100653)2.61853250
53Lymphopenia (HP:0001888)2.58748453
54Abnormality of cells of the lymphoid lineage (HP:0012140)2.51192524
55Abnormality of glycolipid metabolism (HP:0010969)2.48232760
56Abnormality of liposaccharide metabolism (HP:0010968)2.48232760
57Abnormality of glycosphingolipid metabolism (HP:0004343)2.48232760
58Abnormality of the prostate (HP:0008775)2.48168225
59Osteomyelitis (HP:0002754)2.48086580
60Acute myeloid leukemia (HP:0004808)2.47961316
61Pulmonary embolism (HP:0002204)2.47432510
62Chronic diarrhea (HP:0002028)2.47312037
63Peritonitis (HP:0002586)2.43600865
64Abnormality of T cell physiology (HP:0011840)2.43492077
65Increased IgM level (HP:0003496)2.43142868
66Colitis (HP:0002583)2.42519353
67Orchitis (HP:0100796)2.41247616
68Combined immunodeficiency (HP:0005387)2.37322932
69Epistaxis (HP:0000421)2.37069077
70Lymphoma (HP:0002665)2.36920702
71Recurrent pneumonia (HP:0006532)2.34901918
72Hypoplasia of the thymus (HP:0000778)2.34186079
73Dysostosis multiplex (HP:0000943)2.30897513
74Episodic fever (HP:0001954)2.30677847
75Hypoproteinemia (HP:0003075)2.30392022
76Abnormality of macrophages (HP:0004311)2.28204685
77Pulmonary infiltrates (HP:0002113)2.27401008
78Hypergammaglobulinemia (HP:0010702)2.25826972
79Myelodysplasia (HP:0002863)2.25529581
80Encephalitis (HP:0002383)2.25204783
81Autoimmune thrombocytopenia (HP:0001973)2.25017024
82Gastrointestinal stroma tumor (HP:0100723)2.24521686
83Abnormality of the pleura (HP:0002103)2.23783857
84Gingivitis (HP:0000230)2.21237805
85Periodontitis (HP:0000704)2.20904992
86Abnormality of the peritoneum (HP:0002585)2.19803992
87Clubbing of toes (HP:0100760)2.17930216
88Recurrent lower respiratory tract infections (HP:0002783)2.17708429
89Abnormality of DNA repair (HP:0003254)2.16761794
90IgA deficiency (HP:0002720)2.16410229
91Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.16385396
92Hemoptysis (HP:0002105)2.15792119
93Impaired platelet aggregation (HP:0003540)2.14381535
94Abnormal platelet function (HP:0011869)2.14381535
95Gingival bleeding (HP:0000225)2.10187313
96Chest pain (HP:0100749)2.09845872
97Duplicated collecting system (HP:0000081)2.08953289
98Glomerulopathy (HP:0100820)2.08901532
99Viral hepatitis (HP:0006562)2.08051556
100Increased cerebral lipofuscin (HP:0011813)2.07947261
101Syringomyelia (HP:0003396)2.06061650
102Spinal cord lesions (HP:0100561)2.06061650
103Acute lymphatic leukemia (HP:0006721)2.05615174
104Prostate neoplasm (HP:0100787)2.05151846
105Sepsis (HP:0100806)2.04418978
106Pustule (HP:0200039)2.02760511
107Abnormality of the renal collecting system (HP:0004742)2.01402376
108Gangrene (HP:0100758)2.00908790
109Leukopenia (HP:0001882)2.00783838
110Reticulocytopenia (HP:0001896)2.00413652
111Abnormality of the columella (HP:0009929)1.99048617
112Spondylolisthesis (HP:0003302)1.98019162
113Slow saccadic eye movements (HP:0000514)1.97470544
114Abnormality of chromosome stability (HP:0003220)1.94265851
115Amaurosis fugax (HP:0100576)1.94224460
116Abnormality of the endocardium (HP:0004306)1.93558824
117Loss of speech (HP:0002371)1.93499877
118Arterial thrombosis (HP:0004420)1.92997846
119Hematochezia (HP:0002573)1.92417927
120Skin ulcer (HP:0200042)1.90330736
121Anorexia (HP:0002039)1.90229324
122Increased neuronal autofluorescent lipopigment (HP:0002074)1.88837716
123Hypochromic anemia (HP:0001931)1.88771117
124Pulmonary fibrosis (HP:0002206)1.86749381
125Skin rash (HP:0000988)1.86559182
126Papilledema (HP:0001085)1.85540556
127Joint swelling (HP:0001386)1.85189379
128Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.85143903
129Abnormality of the pericardium (HP:0001697)1.84979563
130Long eyelashes (HP:0000527)1.84952835
131Microcytic anemia (HP:0001935)1.84757774
132Polyneuropathy (HP:0001271)1.84641599
133Verrucae (HP:0200043)1.84012293
134Papilloma (HP:0012740)1.84012293
135Keratoconjunctivitis sicca (HP:0001097)1.83609291
136Albinism (HP:0001022)1.81736988
137Agnosia (HP:0010524)1.80178240
138Ectopic kidney (HP:0000086)1.76355147
139Volvulus (HP:0002580)1.75353551

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.15703058
2TXK3.44787462
3IRAK42.85618338
4KIT2.66818809
5MAP3K142.41321261
6BTK2.32098610
7TGFBR22.31613697
8ERN12.25703201
9CSF1R2.18921748
10BLK2.17915734
11JAK32.11487257
12CLK12.10940363
13ZAP702.08976942
14TEC2.00299811
15IKBKE1.87652484
16TYK21.87270275
17SIK31.81722500
18EEF2K1.78758073
19SYK1.66363761
20PIK3CG1.65767641
21IKBKB1.62106101
22ITK1.60807153
23STK101.58980424
24IRAK31.50881300
25TAOK31.47423893
26HCK1.46437681
27LCK1.45885821
28TBK11.38104662
29SIK21.33693742
30PIM11.33306664
31YES11.33151196
32FLT31.29850177
33JAK11.29133443
34MAP3K71.26475811
35STK41.25974226
36BMPR21.24295333
37RIPK41.22199365
38MAP3K101.21269888
39CAMKK21.20651776
40TESK21.19377821
41NLK1.17812695
42LYN1.17496950
43FES1.17251313
44MAP3K111.16997117
45FGR1.11867891
46CSK1.10419622
47EPHB11.09890434
48TRPM71.09303753
49PIM21.08759336
50CHUK1.07971565
51FGFR31.05527607
52MAP3K31.03508299
53MAP2K31.01731849
54BRD40.99569327
55CDK120.94391762
56MARK30.94158528
57VRK10.90859811
58TNIK0.90689981
59ATR0.89948418
60ZAK0.89627647
61ADRBK20.89451425
62PDK10.87981663
63CDK40.87753406
64PRPF4B0.86567101
65TNK20.85801842
66CDK90.84943049
67CDC42BPA0.81886012
68EIF2AK20.80854072
69TAOK10.79435675
70MAP3K60.78693757
71MAP3K10.78016263
72MATK0.76205637
73WNK10.75190927
74MAP3K50.71156982
75CDK80.70902673
76MAPK120.70770850
77RPS6KB20.70713197
78KSR20.70613068
79TGFBR10.66299631
80RPS6KA40.66118621
81TIE10.66064147
82CAMKK10.65727324
83STK380.64750645
84PTK2B0.64209259
85GRK60.64068187
86CDK60.63492211
87CAMK1D0.63438593
88HIPK20.61402467
89MAPK110.61089264
90NME20.60073167
91MAP3K130.60064224
92FYN0.58920700
93NEK90.57679403
94PDPK10.56148798
95CAMK1G0.55540692
96MKNK20.55128655
97LRRK20.54892462
98GRK70.53952220
99RPS6KA60.51287085
100MAPKAPK20.49478401
101PRKCQ0.49234824
102TLK10.48404063
103CDK70.47724144
104JAK20.47557029
105IRAK10.47250800
106MKNK10.46904389
107SGK30.46858084
108MAPK70.46480536
109CDK30.45235690
110MAPKAPK50.44956063
111STK240.44389129
112MAPK40.43792046
113PRKD20.42732436
114ABL10.42369072
115RPS6KL10.42213027
116RPS6KC10.42213027
117KDR0.42195820
118EIF2AK30.41988823
119PDGFRB0.41003047
120SRPK10.39855725
121FGFR40.39323219
122DAPK20.38419044
123CAMK40.38372897
124RET0.38354360
125NEK20.38216267
126MAP3K20.37598244
127MELK0.37058172
128IRAK20.36556586
129DYRK1B0.36411533
130AKT30.36381254
131TAOK20.36163536
132MARK20.35900470
133SCYL20.35849081
134RPS6KA50.35687017
135SGK20.35437482
136MAPK30.34747807
137MOS0.33619654
138EPHA30.33558437
139PRKD10.31366192

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.49896681
2NF-kappa B signaling pathway_Homo sapiens_hsa040642.32962025
3Leishmaniasis_Homo sapiens_hsa051402.18591632
4Measles_Homo sapiens_hsa051622.14923080
5B cell receptor signaling pathway_Homo sapiens_hsa046622.13769484
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.09205927
7Hematopoietic cell lineage_Homo sapiens_hsa046402.07429313
8Type I diabetes mellitus_Homo sapiens_hsa049402.05128336
9Non-homologous end-joining_Homo sapiens_hsa034502.04457777
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.04038524
11Osteoclast differentiation_Homo sapiens_hsa043801.93279151
12DNA replication_Homo sapiens_hsa030301.79444234
13Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.77755680
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.76649735
15Herpes simplex infection_Homo sapiens_hsa051681.66435751
16T cell receptor signaling pathway_Homo sapiens_hsa046601.57427455
17Homologous recombination_Homo sapiens_hsa034401.56431648
18Toll-like receptor signaling pathway_Homo sapiens_hsa046201.55637438
19RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.55019704
20Allograft rejection_Homo sapiens_hsa053301.54321204
21Jak-STAT signaling pathway_Homo sapiens_hsa046301.52542742
22Antigen processing and presentation_Homo sapiens_hsa046121.51081074
23Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.47808997
24NOD-like receptor signaling pathway_Homo sapiens_hsa046211.45195874
25Mismatch repair_Homo sapiens_hsa034301.45034126
26Transcriptional misregulation in cancer_Homo sapiens_hsa052021.44613387
27Fanconi anemia pathway_Homo sapiens_hsa034601.40810266
28Base excision repair_Homo sapiens_hsa034101.40435474
29Other glycan degradation_Homo sapiens_hsa005111.39202319
30Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.34905134
31Toxoplasmosis_Homo sapiens_hsa051451.27717648
32Graft-versus-host disease_Homo sapiens_hsa053321.27647729
33Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.27043800
34Chronic myeloid leukemia_Homo sapiens_hsa052201.26919806
35Acute myeloid leukemia_Homo sapiens_hsa052211.24410126
36Influenza A_Homo sapiens_hsa051641.22471783
37Pertussis_Homo sapiens_hsa051331.22018858
38Chemokine signaling pathway_Homo sapiens_hsa040621.19750139
39Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.17592620
40Hepatitis B_Homo sapiens_hsa051611.16344001
41Asthma_Homo sapiens_hsa053101.15759221
42Phagosome_Homo sapiens_hsa041451.15069343
43Malaria_Homo sapiens_hsa051441.13482450
44Platelet activation_Homo sapiens_hsa046111.11742054
45Apoptosis_Homo sapiens_hsa042101.09920833
46Shigellosis_Homo sapiens_hsa051311.08055973
47Leukocyte transendothelial migration_Homo sapiens_hsa046701.07676277
48Viral myocarditis_Homo sapiens_hsa054161.06264823
49Ribosome_Homo sapiens_hsa030101.05533991
50Tuberculosis_Homo sapiens_hsa051521.02934593
51TNF signaling pathway_Homo sapiens_hsa046681.02397369
52Pancreatic cancer_Homo sapiens_hsa052121.01174224
53Legionellosis_Homo sapiens_hsa051340.99050671
54Glycosaminoglycan degradation_Homo sapiens_hsa005310.98212618
55Staphylococcus aureus infection_Homo sapiens_hsa051500.98158648
56Autoimmune thyroid disease_Homo sapiens_hsa053200.98113139
57Cell cycle_Homo sapiens_hsa041100.96968375
58Spliceosome_Homo sapiens_hsa030400.94106233
59Epstein-Barr virus infection_Homo sapiens_hsa051690.92888405
60Small cell lung cancer_Homo sapiens_hsa052220.88459925
61HTLV-I infection_Homo sapiens_hsa051660.87552630
62Notch signaling pathway_Homo sapiens_hsa043300.87314601
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.83988794
64Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.82889870
65Nucleotide excision repair_Homo sapiens_hsa034200.82214856
66Salmonella infection_Homo sapiens_hsa051320.80395343
67Dorso-ventral axis formation_Homo sapiens_hsa043200.80098037
68p53 signaling pathway_Homo sapiens_hsa041150.78012308
69VEGF signaling pathway_Homo sapiens_hsa043700.77869305
70Viral carcinogenesis_Homo sapiens_hsa052030.77324233
71Amoebiasis_Homo sapiens_hsa051460.73821689
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73132180
73RNA degradation_Homo sapiens_hsa030180.71002572
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70537247
75Non-small cell lung cancer_Homo sapiens_hsa052230.70426636
76Phospholipase D signaling pathway_Homo sapiens_hsa040720.69369745
77Colorectal cancer_Homo sapiens_hsa052100.69034846
78Renal cell carcinoma_Homo sapiens_hsa052110.66476305
79Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.66201487
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.65772728
81MicroRNAs in cancer_Homo sapiens_hsa052060.65756579
82Regulation of autophagy_Homo sapiens_hsa041400.63431155
83mTOR signaling pathway_Homo sapiens_hsa041500.62600823
84Hepatitis C_Homo sapiens_hsa051600.61844926
85Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60662151
86African trypanosomiasis_Homo sapiens_hsa051430.60410981
87Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.59250787
88Inositol phosphate metabolism_Homo sapiens_hsa005620.59114661
89Carbohydrate digestion and absorption_Homo sapiens_hsa049730.59055864
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58363944
91Lysosome_Homo sapiens_hsa041420.57005170
92Choline metabolism in cancer_Homo sapiens_hsa052310.56972472
93Rheumatoid arthritis_Homo sapiens_hsa053230.56519757
94* Endocytosis_Homo sapiens_hsa041440.56497322
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54350316
96Pathways in cancer_Homo sapiens_hsa052000.53299117
97Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.52189551
98mRNA surveillance pathway_Homo sapiens_hsa030150.50143934
99Prolactin signaling pathway_Homo sapiens_hsa049170.49805503
100Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49778512
101GnRH signaling pathway_Homo sapiens_hsa049120.48769812
102FoxO signaling pathway_Homo sapiens_hsa040680.48289616
103HIF-1 signaling pathway_Homo sapiens_hsa040660.47685654
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47410319
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46643515
106Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44514007
107Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.44119382
108Lysine degradation_Homo sapiens_hsa003100.43982395
109Insulin resistance_Homo sapiens_hsa049310.43199653
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42554100
111Systemic lupus erythematosus_Homo sapiens_hsa053220.42097182
112Basal transcription factors_Homo sapiens_hsa030220.41385898
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40569503
114Prostate cancer_Homo sapiens_hsa052150.38957221
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.38771300
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.38638164
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.38199056
118RNA polymerase_Homo sapiens_hsa030200.37700847
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.37520673
120Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36911230
121Pyrimidine metabolism_Homo sapiens_hsa002400.36743164
122Endometrial cancer_Homo sapiens_hsa052130.36296779
123Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36113398
124Ras signaling pathway_Homo sapiens_hsa040140.35854208
125MAPK signaling pathway_Homo sapiens_hsa040100.35435539
126Glioma_Homo sapiens_hsa052140.34552318
127ErbB signaling pathway_Homo sapiens_hsa040120.33594817
128Rap1 signaling pathway_Homo sapiens_hsa040150.33468853
129Long-term potentiation_Homo sapiens_hsa047200.32486630

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