GLB1L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1aminoglycoside antibiotic metabolic process (GO:0030647)8.72945146
2organic cation transport (GO:0015695)8.63084256
3cilium or flagellum-dependent cell motility (GO:0001539)7.49361421
4fusion of sperm to egg plasma membrane (GO:0007342)6.47964264
5drug transmembrane transport (GO:0006855)6.22605467
6sperm motility (GO:0030317)5.97189006
7axonemal dynein complex assembly (GO:0070286)5.78313587
8drug transport (GO:0015893)5.45612404
9urate metabolic process (GO:0046415)5.35603338
10acrosome reaction (GO:0007340)5.19000516
11motile cilium assembly (GO:0044458)5.12083153
12glycoside metabolic process (GO:0016137)5.10092875
13multicellular organism reproduction (GO:0032504)5.08643108
14intraciliary transport (GO:0042073)5.06066119
15epithelial cilium movement (GO:0003351)4.90957648
16sperm-egg recognition (GO:0035036)4.81477421
17acrosome assembly (GO:0001675)4.76049823
18metanephric nephron tubule development (GO:0072234)4.69418455
19metanephric tubule development (GO:0072170)4.69418455
20toxin transport (GO:1901998)4.65030046
21cilium organization (GO:0044782)4.58044073
22plasma membrane fusion (GO:0045026)4.54683873
23response to pheromone (GO:0019236)4.54181099
24cell wall macromolecule metabolic process (GO:0044036)4.51374324
25cell wall macromolecule catabolic process (GO:0016998)4.51374324
26quaternary ammonium group transport (GO:0015697)4.46497812
27cilium assembly (GO:0042384)4.41321710
28cilium morphogenesis (GO:0060271)4.37245013
29piRNA metabolic process (GO:0034587)4.33934824
30spermatid development (GO:0007286)4.28589420
31cell-cell recognition (GO:0009988)4.28566981
32binding of sperm to zona pellucida (GO:0007339)4.22433249
33trivalent inorganic anion homeostasis (GO:0072506)4.22431736
34phosphate ion homeostasis (GO:0055062)4.22431736
35cilium movement (GO:0003341)4.19038509
36left/right axis specification (GO:0070986)4.18409079
37L-fucose catabolic process (GO:0042355)4.13434749
38fucose catabolic process (GO:0019317)4.13434749
39L-fucose metabolic process (GO:0042354)4.13434749
40metanephric nephron epithelium development (GO:0072243)4.13319276
41metanephric epithelium development (GO:0072207)4.12423331
42amino sugar catabolic process (GO:0046348)4.06291846
43epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.99584866
44renal tubule development (GO:0061326)3.97237269
45behavioral response to nicotine (GO:0035095)3.94196557
46regulation of cilium movement (GO:0003352)3.85065651
47reproduction (GO:0000003)3.82961892
48single fertilization (GO:0007338)3.82689880
49oligosaccharide catabolic process (GO:0009313)3.80017893
50excretion (GO:0007588)3.78657119
51microtubule bundle formation (GO:0001578)3.76776062
52nephron tubule development (GO:0072080)3.67256610
53nonmotile primary cilium assembly (GO:0035058)3.62924967
54protein polyglutamylation (GO:0018095)3.48777731
55fucose metabolic process (GO:0006004)3.48240860
56nephron epithelium development (GO:0072009)3.45731102
57male meiosis (GO:0007140)3.44914828
58sulfate transmembrane transport (GO:1902358)3.44464791
59amino-acid betaine transport (GO:0015838)3.44415359
60carnitine transport (GO:0015879)3.44415359
61cornea development in camera-type eye (GO:0061303)3.40201474
62cellular component assembly involved in morphogenesis (GO:0010927)3.39487801
63doxorubicin metabolic process (GO:0044598)3.37401847
64daunorubicin metabolic process (GO:0044597)3.37401847
65polyketide metabolic process (GO:0030638)3.37401847
66nucleoside diphosphate catabolic process (GO:0009134)3.36688201
67regulation of microtubule-based movement (GO:0060632)3.36308705
68sperm capacitation (GO:0048240)3.28722575
69smoothened signaling pathway (GO:0007224)3.27217844
70photoreceptor cell maintenance (GO:0045494)3.24690722
71synaptonemal complex organization (GO:0070193)3.23867555
72ubiquinone biosynthetic process (GO:0006744)3.23723802
73response to folic acid (GO:0051593)3.19519255
74phosphate ion transport (GO:0006817)3.17617110
75tryptophan catabolic process (GO:0006569)3.16582923
76indole-containing compound catabolic process (GO:0042436)3.16582923
77indolalkylamine catabolic process (GO:0046218)3.16582923
78superoxide anion generation (GO:0042554)3.15986611
79mannosylation (GO:0097502)3.11959856
80centriole assembly (GO:0098534)3.10729216
81platelet dense granule organization (GO:0060155)3.10469392
82centriole replication (GO:0007099)3.09008117
83pyrimidine ribonucleoside catabolic process (GO:0046133)3.07414880
84determination of left/right symmetry (GO:0007368)3.06931764
85male meiosis I (GO:0007141)3.05736313
86carnitine metabolic process (GO:0009437)3.04292859
87retinal cone cell development (GO:0046549)3.02521200
88renal absorption (GO:0070293)3.02308975
89DNA methylation involved in gamete generation (GO:0043046)3.01287841
90ubiquinone metabolic process (GO:0006743)2.98955192
91negative regulation of T cell differentiation in thymus (GO:0033085)2.98926234
92protein-cofactor linkage (GO:0018065)2.98711727
93cellular ketone body metabolic process (GO:0046950)2.97854409
94cellular response to vitamin D (GO:0071305)2.96959506
95histamine transport (GO:0051608)2.96193354
96indolalkylamine metabolic process (GO:0006586)2.95167781
97negative regulation of leukocyte chemotaxis (GO:0002689)2.94116002
98polyol catabolic process (GO:0046174)2.93066262
99fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.91844980
100response to peptidoglycan (GO:0032494)2.88314591
101vitamin D metabolic process (GO:0042359)2.88056482
102cell projection assembly (GO:0030031)2.85744349
103DNA deamination (GO:0045006)2.84604831
104determination of bilateral symmetry (GO:0009855)2.84025016
105kynurenine metabolic process (GO:0070189)2.83373933
106neural tube formation (GO:0001841)2.82478857
107ventricular system development (GO:0021591)2.81722400
108water-soluble vitamin biosynthetic process (GO:0042364)2.81554484
109sulfate transport (GO:0008272)2.80495214
110preassembly of GPI anchor in ER membrane (GO:0016254)2.80109087
111RNA destabilization (GO:0050779)2.80097530
112detection of light stimulus involved in visual perception (GO:0050908)2.78872277
113detection of light stimulus involved in sensory perception (GO:0050962)2.78872277
114nonribosomal peptide biosynthetic process (GO:0019184)2.78022755
115specification of symmetry (GO:0009799)2.77787774
116left/right pattern formation (GO:0060972)2.75167375
117negative regulation of telomere maintenance (GO:0032205)2.74557510
118fertilization (GO:0009566)2.74459675
119polyol transport (GO:0015791)2.74024184
120cell differentiation involved in metanephros development (GO:0072202)2.72810534
121ketone body metabolic process (GO:1902224)2.71795986
122GPI anchor metabolic process (GO:0006505)2.70173508
123protein localization to cilium (GO:0061512)2.69247862
124nucleoside diphosphate phosphorylation (GO:0006165)2.68561373
125oxidative demethylation (GO:0070989)2.68326545
126spermatogenesis (GO:0007283)2.67458194
127male gamete generation (GO:0048232)2.66375064
128response to xenobiotic stimulus (GO:0009410)2.65862970
129aldehyde catabolic process (GO:0046185)2.65540461
130phospholipid scrambling (GO:0017121)2.65030386
131positive regulation of cellular amide metabolic process (GO:0034250)2.64691586
132primary alcohol catabolic process (GO:0034310)2.64482065
133negative regulation of metanephros development (GO:0072217)2.64472927
134exogenous drug catabolic process (GO:0042738)2.64381505
135one-carbon compound transport (GO:0019755)2.64380473
136protein complex biogenesis (GO:0070271)2.64189266
137amino-acid betaine metabolic process (GO:0006577)2.63061193
138lysine catabolic process (GO:0006554)2.62460355
139lysine metabolic process (GO:0006553)2.62460355
140glucosamine-containing compound catabolic process (GO:1901072)2.62359423
141synaptonemal complex assembly (GO:0007130)2.62095457
142inner ear receptor stereocilium organization (GO:0060122)2.61399542
143tryptophan metabolic process (GO:0006568)2.59858548
144ATP synthesis coupled proton transport (GO:0015986)2.59073355
145energy coupled proton transport, down electrochemical gradient (GO:0015985)2.59073355
146quinone biosynthetic process (GO:1901663)2.58366419
147somite development (GO:0061053)2.57577027
148mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.57336588
149mesenchymal-epithelial cell signaling (GO:0060638)2.57202316
150neutrophil mediated immunity (GO:0002446)2.56821817
151seminiferous tubule development (GO:0072520)2.56445910
152fucosylation (GO:0036065)2.54291359
153photoreceptor cell development (GO:0042461)2.54270534
154microtubule-based movement (GO:0007018)2.53703438
155peptide catabolic process (GO:0043171)2.53321557
156spinal cord motor neuron differentiation (GO:0021522)2.52621497
157regulation of apoptotic process involved in morphogenesis (GO:1902337)2.52403587
158axoneme assembly (GO:0035082)2.52164133
159sulfur compound transport (GO:0072348)2.50930644
160pyrimidine nucleobase catabolic process (GO:0006208)2.47444176
161forebrain morphogenesis (GO:0048853)2.47412829
162GPI anchor biosynthetic process (GO:0006506)2.47366172
163kidney morphogenesis (GO:0060993)2.47324771
164cellular biogenic amine catabolic process (GO:0042402)2.47199834
165amine catabolic process (GO:0009310)2.47199834
166sequestering of extracellular ligand from receptor (GO:0035581)2.47171034
167benzene-containing compound metabolic process (GO:0042537)2.46685882
168cellular carbohydrate catabolic process (GO:0044275)2.46518880
169mitochondrial respiratory chain complex I assembly (GO:0032981)2.46418629
170NADH dehydrogenase complex assembly (GO:0010257)2.46418629
171mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.46418629
172dopamine transport (GO:0015872)2.44904452
173behavioral response to ethanol (GO:0048149)2.43068002
174mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.43009142
175drug catabolic process (GO:0042737)2.42662753
176detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.40731999
177parturition (GO:0007567)2.39162885
178C-terminal protein lipidation (GO:0006501)2.39102790
179autophagic vacuole fusion (GO:0000046)2.38153968
180C-terminal protein amino acid modification (GO:0018410)2.37222236
181glycerophospholipid catabolic process (GO:0046475)2.36994360
182pyrimidine-containing compound transmembrane transport (GO:0072531)2.36526658

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.98667742
2ZNF274_21170338_ChIP-Seq_K562_Hela3.80445661
3GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.34614672
4EZH2_22144423_ChIP-Seq_EOC_Human3.21506143
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.03686702
6SCL_19346495_ChIP-Seq_HPC-7_Human2.94152745
7BP1_19119308_ChIP-ChIP_Hs578T_Human2.78610811
8LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.73656902
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.70613205
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.48014174
11IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.34861532
12RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.34008155
13CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.31793028
14CTBP2_25329375_ChIP-Seq_LNCAP_Human2.15535041
15IGF1R_20145208_ChIP-Seq_DFB_Human2.15133240
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.04877635
17CTBP1_25329375_ChIP-Seq_LNCAP_Human2.03093363
18LMO2_20887958_ChIP-Seq_HPC-7_Mouse2.02511057
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.99020202
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.97079750
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.96352400
22EWS_26573619_Chip-Seq_HEK293_Human1.92540484
23IRF8_27001747_Chip-Seq_BMDM_Mouse1.89887972
24POU3F2_20337985_ChIP-ChIP_501MEL_Human1.89056512
25P300_19829295_ChIP-Seq_ESCs_Human1.88757024
26EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.87861044
27GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.83797340
28IRF8_21731497_ChIP-ChIP_J774_Mouse1.83239594
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.81761061
30MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.75516089
31SUZ12_27294783_Chip-Seq_NPCs_Mouse1.74919064
32PCGF2_27294783_Chip-Seq_NPCs_Mouse1.74662928
33FUS_26573619_Chip-Seq_HEK293_Human1.69970245
34STAT1_17558387_ChIP-Seq_HELA_Human1.68611776
35PIAS1_25552417_ChIP-Seq_VCAP_Human1.68535578
36TAF15_26573619_Chip-Seq_HEK293_Human1.68501502
37GABP_17652178_ChIP-ChIP_JURKAT_Human1.67335911
38* NFE2_27457419_Chip-Seq_LIVER_Mouse1.65361080
39IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.64070866
40STAT6_21828071_ChIP-Seq_BEAS2B_Human1.63168085
41NR3C1_21868756_ChIP-Seq_MCF10A_Human1.61614924
42MYB_21317192_ChIP-Seq_ERMYB_Mouse1.61585112
43PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.60151546
44FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.59270482
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57833064
46TP53_22573176_ChIP-Seq_HFKS_Human1.55026137
47TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54569082
48TOP2B_26459242_ChIP-Seq_MCF-7_Human1.54030096
49GBX2_23144817_ChIP-Seq_PC3_Human1.53504468
50BCAT_22108803_ChIP-Seq_LS180_Human1.50563410
51TAL1_26923725_Chip-Seq_HPCs_Mouse1.49950055
52SMAD4_21799915_ChIP-Seq_A2780_Human1.48456556
53VDR_24787735_ChIP-Seq_THP-1_Human1.48005201
54FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.44351841
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.42720711
56ETV2_25802403_ChIP-Seq_MESCs_Mouse1.40922870
57FOXA1_25329375_ChIP-Seq_VCAP_Human1.40008032
58FOXA1_27270436_Chip-Seq_PROSTATE_Human1.40008032
59AR_25329375_ChIP-Seq_VCAP_Human1.39575911
60AR_20517297_ChIP-Seq_VCAP_Human1.39542683
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39513942
62CDX2_19796622_ChIP-Seq_MESCs_Mouse1.37803404
63* P53_22387025_ChIP-Seq_ESCs_Mouse1.37598395
64BMI1_23680149_ChIP-Seq_NPCS_Mouse1.35568528
65IRF1_19129219_ChIP-ChIP_H3396_Human1.35315322
66NCOR_22424771_ChIP-Seq_293T_Human1.35200848
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34595040
68SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.33796975
69STAT3_18555785_Chip-Seq_ESCs_Mouse1.33771060
70STAT3_23295773_ChIP-Seq_U87_Human1.33708581
71MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.33534703
72* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.32588254
73OCT4_18555785_Chip-Seq_ESCs_Mouse1.32551212
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.31767139
75EZH2_27294783_Chip-Seq_NPCs_Mouse1.30520465
76SUZ12_18555785_Chip-Seq_ESCs_Mouse1.30378485
77UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30203121
78IKZF1_21737484_ChIP-ChIP_HCT116_Human1.29296497
79VDR_22108803_ChIP-Seq_LS180_Human1.28854513
80CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.28806141
81SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.26193885
82ESRRB_18555785_Chip-Seq_ESCs_Mouse1.26146521
83GATA3_21878914_ChIP-Seq_MCF-7_Human1.26127575
84Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.25979342
85TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.25179300
86TCF4_22108803_ChIP-Seq_LS180_Human1.24903280
87NANOG_18555785_Chip-Seq_ESCs_Mouse1.24900085
88MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.24727255
89PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23632397
90ER_23166858_ChIP-Seq_MCF-7_Human1.23018284
91RAD21_21589869_ChIP-Seq_MESCs_Mouse1.22950546
92TCF4_23295773_ChIP-Seq_U87_Human1.22816500
93TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.21380511
94SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21285735
95* CRX_20693478_ChIP-Seq_RETINA_Mouse1.20880875
96NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.20770704
97MYC_18940864_ChIP-ChIP_HL60_Human1.20766927
98KDM2B_26808549_Chip-Seq_REH_Human1.19708321
99MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.18644951
100SMAD3_21741376_ChIP-Seq_EPCs_Human1.18009944
101MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.17578095
102CBX2_27304074_Chip-Seq_ESCs_Mouse1.17560094
103NANOG_19829295_ChIP-Seq_ESCs_Human1.17307909
104SOX2_19829295_ChIP-Seq_ESCs_Human1.17307909
105P300_18555785_Chip-Seq_ESCs_Mouse1.17076827
106FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.16714690
107RUNX2_22187159_ChIP-Seq_PCA_Human1.16622923
108* PU1_27457419_Chip-Seq_LIVER_Mouse1.15840577
109SOX2_22085726_ChIP-Seq_NPCs_Mouse1.15128310
110DROSHA_22980978_ChIP-Seq_HELA_Human1.13796512
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12927495
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12927495
113KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.12926130
114FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.12711186
115PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12379539
116* E2F1_18555785_Chip-Seq_ESCs_Mouse1.11474865
117* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.10973448
118* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.10480363
119* CTCF_18555785_Chip-Seq_ESCs_Mouse1.10249041
120GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10238765
121STAT4_19710469_ChIP-ChIP_TH1__Mouse1.10001875
122FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09926296
123KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09651476
124* KLF4_18555785_Chip-Seq_ESCs_Mouse1.09076119
125RNF2_27304074_Chip-Seq_NSC_Mouse1.08959799
126CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.08686201
127* PU_27001747_Chip-Seq_BMDM_Mouse1.08036510
128PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.07806213
129SMAD4_21741376_ChIP-Seq_EPCs_Human1.07806073
130* ZFX_18555785_Chip-Seq_ESCs_Mouse1.07646856
131REST_21632747_ChIP-Seq_MESCs_Mouse1.06591324
132* NMYC_18555785_Chip-Seq_ESCs_Mouse1.06370812
133TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06237986
134MYC_19829295_ChIP-Seq_ESCs_Human1.05540092
135EST1_17652178_ChIP-ChIP_JURKAT_Human1.05402444
136* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04331400
137HOXB7_26014856_ChIP-Seq_BT474_Human1.04275386
138SALL1_21062744_ChIP-ChIP_HESCs_Human1.03334471
139SOX2_18555785_Chip-Seq_ESCs_Mouse1.03257129
140EGR1_23403033_ChIP-Seq_LIVER_Mouse1.03030586
141CMYC_18555785_Chip-Seq_ESCs_Mouse1.02279127
142GF1_26923725_Chip-Seq_HPCs_Mouse1.02097490
143GATA3_21867929_ChIP-Seq_CD8_Mouse1.02011689
144SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.01932047
145* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.01823480
146CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.01816580
147AR_21572438_ChIP-Seq_LNCaP_Human1.01463366
148SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.01102228
149PRDM14_20953172_ChIP-Seq_ESCs_Human1.00429862
150RUNX1_22412390_ChIP-Seq_EML_Mouse1.00222726
151ZFP57_27257070_Chip-Seq_ESCs_Mouse0.99831307
152GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.99044947
153SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99024093
154SRF_21415370_ChIP-Seq_HL-1_Mouse0.98734677
155CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.97860823
156VDR_24763502_ChIP-Seq_THP-1_Human0.97593953
157PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97519813
158TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97453734
159SPI1_23547873_ChIP-Seq_NB4_Human0.97392164
160BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.97338787
161CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96541378
162* OCT4_21477851_ChIP-Seq_ESCs_Mouse0.96381379
163* TAF2_19829295_ChIP-Seq_ESCs_Human0.96023643
164EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.95983655
165OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95523094
166RBPJ_22232070_ChIP-Seq_NCS_Mouse0.94632191
167CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.94547026
168* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.91554876
169KAP1_22055183_ChIP-Seq_ESCs_Mouse0.91197361
170* SMAD1_18555785_Chip-Seq_ESCs_Mouse0.91163681
171PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.90752526
172WDR5_24793694_ChIP-Seq_LNCAP_Human0.89923303
173CBP_20019798_ChIP-Seq_JUKART_Human0.89360862
174IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.89360862
175* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.89099714
176HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.88811923

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization5.70071275
2MP0001958_emphysema3.99723241
3MP0002653_abnormal_ependyma_morphology3.88932858
4MP0008875_abnormal_xenobiotic_pharmacok3.87663262
5MP0004043_abnormal_pH_regulation3.57049095
6MP0004019_abnormal_vitamin_homeostasis3.33436174
7MP0005377_hearing/vestibular/ear_phenot2.85898273
8MP0003878_abnormal_ear_physiology2.85898273
9MP0001765_abnormal_ion_homeostasis2.69452513
10MP0004133_heterotaxia2.60369467
11MP0005174_abnormal_tail_pigmentation2.28609981
12MP0001984_abnormal_olfaction2.27461913
13MP0005332_abnormal_amino_acid2.27145740
14MP0003724_increased_susceptibility_to2.24822021
15MP0005551_abnormal_eye_electrophysiolog2.22326452
16MP0005670_abnormal_white_adipose2.19967078
17MP0008789_abnormal_olfactory_epithelium2.17097765
18MP0002009_preneoplasia2.13719421
19MP0005636_abnormal_mineral_homeostasis2.12452070
20MP0005360_urolithiasis2.10921036
21MP0009643_abnormal_urine_homeostasis2.09754977
22MP0003698_abnormal_male_reproductive2.07844079
23MP0003136_yellow_coat_color2.04729929
24MP0002136_abnormal_kidney_physiology2.01136788
25MP0006072_abnormal_retinal_apoptosis1.91374443
26MP0001929_abnormal_gametogenesis1.87230166
27MP0000569_abnormal_digit_pigmentation1.81696572
28MP0005645_abnormal_hypothalamus_physiol1.81328511
29MP0006054_spinal_hemorrhage1.80244780
30MP0008877_abnormal_DNA_methylation1.80000918
31MP0005253_abnormal_eye_physiology1.79482080
32MP0006292_abnormal_olfactory_placode1.78652848
33MP0005646_abnormal_pituitary_gland1.75795692
34MP0001835_abnormal_antigen_presentation1.73287721
35MP0002138_abnormal_hepatobiliary_system1.66942117
36MP0001529_abnormal_vocalization1.66376717
37MP0002396_abnormal_hematopoietic_system1.65909795
38MP0000372_irregular_coat_pigmentation1.64409532
39MP0002928_abnormal_bile_duct1.63760180
40MP0003880_abnormal_central_pattern1.63126526
41MP0003195_calcinosis1.61863190
42MP0002132_abnormal_respiratory_system1.61503950
43MP0005058_abnormal_lysosome_morphology1.61424335
44MP0002160_abnormal_reproductive_system1.61187987
45MP0002277_abnormal_respiratory_mucosa1.59819956
46MP0004142_abnormal_muscle_tone1.59065584
47MP0005084_abnormal_gallbladder_morpholo1.56448398
48MP0005503_abnormal_tendon_morphology1.54353659
49MP0003011_delayed_dark_adaptation1.53184141
50MP0000383_abnormal_hair_follicle1.53063940
51MP0000631_abnormal_neuroendocrine_gland1.52580142
52MP0003172_abnormal_lysosome_physiology1.50457552
53MP0000015_abnormal_ear_pigmentation1.49365257
54MP0005365_abnormal_bile_salt1.45801826
55MP0009046_muscle_twitch1.45108698
56MP0002876_abnormal_thyroid_physiology1.44400797
57MP0002998_abnormal_bone_remodeling1.44003303
58MP0002210_abnormal_sex_determination1.41370378
59MP0002822_catalepsy1.40601166
60MP0005394_taste/olfaction_phenotype1.37779998
61MP0005499_abnormal_olfactory_system1.37779998
62MP0002837_dystrophic_cardiac_calcinosis1.36248834
63MP0001986_abnormal_taste_sensitivity1.35964785
64MP0001756_abnormal_urination1.34748559
65MP0009745_abnormal_behavioral_response1.34618077
66MP0005409_darkened_coat_color1.34538591
67MP0003718_maternal_effect1.33090440
68MP0005389_reproductive_system_phenotype1.32072596
69MP0003183_abnormal_peptide_metabolism1.28322049
70MP0001145_abnormal_male_reproductive1.28099681
71MP0001968_abnormal_touch/_nociception1.26182496
72MP0002419_abnormal_innate_immunity1.23377274
73MP0000371_diluted_coat_color1.22420590
74MP0002735_abnormal_chemical_nociception1.21632873
75MP0002166_altered_tumor_susceptibility1.21307855
76MP0002148_abnormal_hypersensitivity_rea1.21080166
77MP0002909_abnormal_adrenal_gland1.20912958
78MP0003122_maternal_imprinting1.20092742
79MP0002135_abnormal_kidney_morphology1.18908365
80MP0002102_abnormal_ear_morphology1.18476120
81MP0003279_aneurysm1.18207326
82MP0006276_abnormal_autonomic_nervous1.17364887
83MP0001485_abnormal_pinna_reflex1.15649581
84MP0003787_abnormal_imprinting1.15376336
85MP0000538_abnormal_urinary_bladder1.14823624
86MP0005195_abnormal_posterior_eye1.11537701
87MP0008872_abnormal_physiological_respon1.10298086
88MP0004147_increased_porphyrin_level1.09772957
89MP0001970_abnormal_pain_threshold1.09717834
90MP0002272_abnormal_nervous_system1.08028729
91MP0000026_abnormal_inner_ear1.07483774
92MP0003121_genomic_imprinting1.06315175
93MP0002736_abnormal_nociception_after1.06188825
94MP0009785_altered_susceptibility_to1.05305189
95MP0008995_early_reproductive_senescence1.04905811
96MP0000049_abnormal_middle_ear1.04300366
97MP0001764_abnormal_homeostasis1.03926627
98MP0003252_abnormal_bile_duct1.03227459
99MP0001905_abnormal_dopamine_level1.02733266
100MP0003795_abnormal_bone_structure1.00383622
101MP0002557_abnormal_social/conspecific_i1.00306224
102MP0009764_decreased_sensitivity_to0.99935757
103MP0000653_abnormal_sex_gland0.99815342
104MP0002572_abnormal_emotion/affect_behav0.99506355
105MP0005025_abnormal_response_to0.99497687
106MP0002161_abnormal_fertility/fecundity0.98652942
107MP0004885_abnormal_endolymph0.98227312
108MP0001486_abnormal_startle_reflex0.98210238
109MP0001293_anophthalmia0.97777876
110MP0000427_abnormal_hair_cycle0.97769696
111MP0000566_synostosis0.97730856
112MP0004381_abnormal_hair_follicle0.97695623
113MP0002115_abnormal_skeleton_extremities0.97243356
114MP0002234_abnormal_pharynx_morphology0.96812874
115MP0000685_abnormal_immune_system0.96446049
116MP0010030_abnormal_orbit_morphology0.95513447
117MP0004742_abnormal_vestibular_system0.95486374
118MP0001542_abnormal_bone_strength0.95196537
119MP0005408_hypopigmentation0.93335068
120MP0005000_abnormal_immune_tolerance0.92699378
121MP0005257_abnormal_intraocular_pressure0.91285132
122MP0008438_abnormal_cutaneous_collagen0.90657304
123MP0005391_vision/eye_phenotype0.90307948
124MP0005171_absent_coat_pigmentation0.90146119
125MP0010386_abnormal_urinary_bladder0.89636329
126MP0003186_abnormal_redox_activity0.87353560
127MP0002075_abnormal_coat/hair_pigmentati0.87212828
128MP0000681_abnormal_thyroid_gland0.86969344
129MP0009379_abnormal_foot_pigmentation0.86913487
130MP0008469_abnormal_protein_level0.86653381
131MP0002006_tumorigenesis0.85214472
132MP0003937_abnormal_limbs/digits/tail_de0.84564699
133MP0003315_abnormal_perineum_morphology0.84477742
134MP0001790_abnormal_immune_system0.83723589
135MP0005387_immune_system_phenotype0.83723589
136MP0003283_abnormal_digestive_organ0.83616951
137MP0002067_abnormal_sensory_capabilities0.82875010
138MP0005085_abnormal_gallbladder_physiolo0.82390751
139MP0002733_abnormal_thermal_nociception0.82196033
140MP0002452_abnormal_antigen_presenting0.82095616
141MP0003436_decreased_susceptibility_to0.81537899
142MP0001845_abnormal_inflammatory_respons0.81009087
143MP0002420_abnormal_adaptive_immunity0.80807381
144MP0001819_abnormal_immune_cell0.80745098
145MP0002752_abnormal_somatic_nervous0.80077693
146MP0010678_abnormal_skin_adnexa0.79672153
147MP0002168_other_aberrant_phenotype0.78886846
148MP0002095_abnormal_skin_pigmentation0.78637491
149MP0002282_abnormal_trachea_morphology0.78210534
150MP0002139_abnormal_hepatobiliary_system0.77846749
151MP0000163_abnormal_cartilage_morphology0.77577081
152MP0002064_seizures0.77358978
153MP0001663_abnormal_digestive_system0.77358338
154MP0002933_joint_inflammation0.76993415
155MP0001324_abnormal_eye_pigmentation0.76740689
156MP0002734_abnormal_mechanical_nocicepti0.76301425
157MP0002177_abnormal_outer_ear0.76008857
158MP0002723_abnormal_immune_serum0.75893345
159MP0000490_abnormal_crypts_of0.75577631
160MP0000230_abnormal_systemic_arterial0.75328747
161MP0002638_abnormal_pupillary_reflex0.74766140
162MP0001502_abnormal_circadian_rhythm0.74426807
163MP0000778_abnormal_nervous_system0.73888283
164MP0008058_abnormal_DNA_repair0.73668401
165MP0002113_abnormal_skeleton_development0.72331889
166MP0001186_pigmentation_phenotype0.71161907
167MP0001188_hyperpigmentation0.70142758
168MP0004808_abnormal_hematopoietic_stem0.69387397
169MP0002938_white_spotting0.68335791
170MP0001533_abnormal_skeleton_physiology0.67113482
171MP0005464_abnormal_platelet_physiology0.65732701
172MP0005390_skeleton_phenotype0.65235305
173MP0002133_abnormal_respiratory_system0.65205843

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.58162253
2Absent/shortened dynein arms (HP:0200106)5.56112467
3Dynein arm defect of respiratory motile cilia (HP:0012255)5.56112467
4Metabolic alkalosis (HP:0200114)5.29772143
5Hypomagnesemia (HP:0002917)5.13105252
6Polyuria (HP:0000103)5.10777428
7Increased circulating renin level (HP:0000848)5.05103182
8Hypokalemic alkalosis (HP:0001949)4.91932213
9Hyperactive renin-angiotensin system (HP:0000841)4.88342446
10Pancreatic fibrosis (HP:0100732)4.80522296
11Pancreatic cysts (HP:0001737)4.73512830
12Abnormal urine output (HP:0012590)4.71361209
13Molar tooth sign on MRI (HP:0002419)4.70695500
14Abnormality of midbrain morphology (HP:0002418)4.70695500
15Abnormality of renal excretion (HP:0011036)4.61532847
16Abnormality of chloride homeostasis (HP:0011422)4.51497840
17Polydipsia (HP:0001959)4.50594744
18Abnormal drinking behavior (HP:0030082)4.50594744
19Abnormality of magnesium homeostasis (HP:0004921)4.30132467
20Tetany (HP:0001281)3.98256887
21Abnormal respiratory motile cilium morphology (HP:0005938)3.72911142
22Abnormal respiratory epithelium morphology (HP:0012253)3.72911142
23Abnormal respiratory motile cilium physiology (HP:0012261)3.60611542
24Cystic liver disease (HP:0006706)3.56408152
25Abnormality of renin-angiotensin system (HP:0000847)3.47819155
26Abnormality of the renal medulla (HP:0100957)3.35623126
27Hypercalciuria (HP:0002150)3.29613171
28Vacuolated lymphocytes (HP:0001922)3.29016249
29Proximal tubulopathy (HP:0000114)3.27375533
30Chronic hepatic failure (HP:0100626)3.26586873
31Hyperaldosteronism (HP:0000859)3.26222218
32Occipital encephalocele (HP:0002085)3.26044796
33Chronic sinusitis (HP:0011109)3.23073370
34Renal tubular acidosis (HP:0001947)3.08491511
35Alkalosis (HP:0001948)3.00218796
36Abnormal ciliary motility (HP:0012262)2.94971823
37Nephronophthisis (HP:0000090)2.92071534
38Abnormality of glutamine family amino acid metabolism (HP:0010902)2.90086896
39Nephrocalcinosis (HP:0000121)2.89905662
40Rhinitis (HP:0012384)2.89471855
41Absent rod-and cone-mediated responses on ERG (HP:0007688)2.81778769
42Aplasia/Hypoplasia of the tongue (HP:0010295)2.77970593
43Chronic otitis media (HP:0000389)2.73828188
44Gait imbalance (HP:0002141)2.73394507
45Congenital primary aphakia (HP:0007707)2.70921980
46Gout (HP:0001997)2.66624727
47Chronic bronchitis (HP:0004469)2.65945704
48Postaxial foot polydactyly (HP:0001830)2.63911776
49Renal salt wasting (HP:0000127)2.62373712
50Anencephaly (HP:0002323)2.61165367
51Hydroxyprolinuria (HP:0003080)2.54918268
52Abnormality of proline metabolism (HP:0010907)2.54918268
53Type II lissencephaly (HP:0007260)2.54023167
54Sclerocornea (HP:0000647)2.53847026
55Congenital stationary night blindness (HP:0007642)2.50514196
56Male pseudohermaphroditism (HP:0000037)2.49825922
57Pulmonary artery stenosis (HP:0004415)2.45187275
58Nephrogenic diabetes insipidus (HP:0009806)2.44022761
59Furrowed tongue (HP:0000221)2.39847879
60Nasal polyposis (HP:0100582)2.39026252
61Tubular atrophy (HP:0000092)2.37345000
62Abolished electroretinogram (ERG) (HP:0000550)2.32064734
63Reduced antithrombin III activity (HP:0001976)2.31861085
64Elfin facies (HP:0004428)2.30342253
65Hyperglycinuria (HP:0003108)2.29966437
66Reticulocytopenia (HP:0001896)2.25211460
67Stage 5 chronic kidney disease (HP:0003774)2.24392201
68Postaxial hand polydactyly (HP:0001162)2.19420519
69Neonatal short-limb short stature (HP:0008921)2.19020974
70Hypokalemia (HP:0002900)2.18733143
71Abnormality of the renal cortex (HP:0011035)2.17584481
72Abnormality of renal resorption (HP:0011038)2.14424104
73Bile duct proliferation (HP:0001408)2.08623511
74Abnormal biliary tract physiology (HP:0012439)2.08623511
75Genital tract atresia (HP:0001827)2.08365363
76Renal tubular dysfunction (HP:0000124)2.07731197
77Hyperventilation (HP:0002883)2.05222636
78Hyperuricemia (HP:0002149)2.04914541
79Increased purine levels (HP:0004368)2.04914541
80Absent frontal sinuses (HP:0002688)2.04808394
81Generalized aminoaciduria (HP:0002909)2.03737929
82Vaginal atresia (HP:0000148)2.03241559
83Decreased central vision (HP:0007663)2.00883011
84Bony spicule pigmentary retinopathy (HP:0007737)1.99463446
85Aplasia/Hypoplasia of the spleen (HP:0010451)1.96092107
86Acute necrotizing encephalopathy (HP:0006965)1.95042197
87Infertility (HP:0000789)1.94945158
88Bronchiectasis (HP:0002110)1.94801991
89Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.92460106
90Abnormality of the nasal mucosa (HP:0000433)1.92398593
91Aplasia/Hypoplasia of the tibia (HP:0005772)1.92239209
92Asplenia (HP:0001746)1.91551230
93Abnormality of potassium homeostasis (HP:0011042)1.91453108
94Bronchitis (HP:0012387)1.90747960
95Glycosuria (HP:0003076)1.89798103
96Abnormality of urine glucose concentration (HP:0011016)1.89798103
97Alveolar cell carcinoma (HP:0006519)1.89572737
98Preaxial hand polydactyly (HP:0001177)1.89457652
99Oculomotor apraxia (HP:0000657)1.88142504
100Concave nail (HP:0001598)1.87941421
101IgM deficiency (HP:0002850)1.87516457
102Retinitis pigmentosa (HP:0000510)1.86865928
103Tubulointerstitial fibrosis (HP:0005576)1.86687821
104Recurrent sinusitis (HP:0011108)1.84266481
105Attenuation of retinal blood vessels (HP:0007843)1.82854128
106Myositis (HP:0100614)1.81532840
107Widely patent fontanelles and sutures (HP:0004492)1.80750463
108Short tibia (HP:0005736)1.79787552
109Hypophosphatemia (HP:0002148)1.79008982
110Abnormal urine phosphate concentration (HP:0012599)1.78946267
111Aortic valve stenosis (HP:0001650)1.78567861
112Retrobulbar optic neuritis (HP:0100654)1.77997109
113Optic neuritis (HP:0100653)1.77997109
114Median cleft lip (HP:0000161)1.77859360
115Recurrent otitis media (HP:0000403)1.77666505
116Orchitis (HP:0100796)1.76705990
117Abnormality of purine metabolism (HP:0004352)1.75805482
1183-Methylglutaconic aciduria (HP:0003535)1.74737326
119Vascular calcification (HP:0004934)1.73766355
120Type I transferrin isoform profile (HP:0003642)1.73335181
121Progressive macrocephaly (HP:0004481)1.71042600
122Mitochondrial inheritance (HP:0001427)1.71001008
123Hyperphosphaturia (HP:0003109)1.70981739
124Abnormality of macular pigmentation (HP:0008002)1.70555908
125Metaphyseal dysplasia (HP:0100255)1.69452213
126Tubulointerstitial abnormality (HP:0001969)1.68784834
127Supernumerary spleens (HP:0009799)1.67742170
128Cerebellar dysplasia (HP:0007033)1.66860822
129Abnormal rod and cone electroretinograms (HP:0008323)1.66528930
130Tubulointerstitial nephritis (HP:0001970)1.65535767
131Congenital, generalized hypertrichosis (HP:0004540)1.65275178
132Cardiovascular calcification (HP:0011915)1.64901690
133Renal dysplasia (HP:0000110)1.64673754
134Acute encephalopathy (HP:0006846)1.63863032
135Optic disc pallor (HP:0000543)1.63448027
136Disproportionate short-trunk short stature (HP:0003521)1.62685474
137Male infertility (HP:0003251)1.62401188
138Dysostosis multiplex (HP:0000943)1.62310954
139Absent speech (HP:0001344)1.61922673
140True hermaphroditism (HP:0010459)1.60940159
141Large eyes (HP:0001090)1.60476678
142Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.59837977
143Medial flaring of the eyebrow (HP:0010747)1.59641878
144Abnormal mitochondria in muscle tissue (HP:0008316)1.59294229
145Hypothermia (HP:0002045)1.59149923
146Poor coordination (HP:0002370)1.58369772
147Abnormality of macrophages (HP:0004311)1.57897193
148Enlarged kidneys (HP:0000105)1.57150703
149Retinal dysplasia (HP:0007973)1.55388835
150Abnormality of molar morphology (HP:0011070)1.54603045
151Abnormality of molar (HP:0011077)1.54603045
152Renal cortical cysts (HP:0000803)1.54273347
153Keratoconus (HP:0000563)1.52925387
154Increased corneal curvature (HP:0100692)1.52925387
155Aganglionic megacolon (HP:0002251)1.52303964
156Increased CSF lactate (HP:0002490)1.52002326
157Congenital hepatic fibrosis (HP:0002612)1.51754141
158Recurrent abscess formation (HP:0002722)1.51702305
159Focal motor seizures (HP:0011153)1.50618038
160Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.50565703
161Abnormal protein N-linked glycosylation (HP:0012347)1.50565703
162Abnormal protein glycosylation (HP:0012346)1.50565703
163Abnormal glycosylation (HP:0012345)1.50565703
164Decreased circulating renin level (HP:0003351)1.50169440
165Large for gestational age (HP:0001520)1.49497526
166Hepatocellular necrosis (HP:0001404)1.48407438
167Nephropathy (HP:0000112)1.48222482
168Multicystic kidney dysplasia (HP:0000003)1.48119707
169Narrow forehead (HP:0000341)1.43237133

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK45.14033003
2WNK34.26362715
3FRK4.02464820
4PDK33.48734404
5PDK43.48734404
6TAOK33.28756000
7OXSR13.20990205
8MAP4K22.98133353
9MST42.60291125
10PDK22.60203410
11NUAK12.42469016
12IRAK32.42455884
13CASK2.27902852
14STK392.24246359
15TNIK2.12744938
16IRAK22.12676892
17IRAK42.11347865
18MAP3K142.05783547
19TESK12.00718211
20IRAK11.95811348
21KIT1.90322533
22TLK11.88287728
23NLK1.87211345
24NME21.81956474
25TEC1.63698330
26MKNK21.55456369
27BCKDK1.51171610
28PNCK1.47261817
29TGFBR11.47178808
30ACVR1B1.46399002
31MAPKAPK31.45755884
32INSRR1.44242964
33WNK11.43666733
34ICK1.33457311
35BTK1.32968634
36RIPK41.32067402
37CSNK1G11.31872814
38IKBKE1.30473264
39MUSK1.28114199
40TXK1.23436382
41BLK1.16221993
42MAP3K41.15753664
43DYRK21.14263221
44TGFBR21.12984007
45STK161.09499188
46VRK21.07813721
47PTK2B1.07311413
48ADRBK11.06874777
49ERBB31.06356541
50SGK21.06223295
51SGK2231.05625028
52SGK4941.05625028
53YES11.04059764
54PIM21.03579530
55PLK21.02678496
56MAPK150.99621217
57PRKD20.99376846
58FES0.97471541
59EIF2AK30.96474413
60PRKCI0.96457151
61TNK20.96107948
62VRK10.94886017
63SRPK10.93568305
64GRK70.92511032
65CLK10.89320632
66MARK10.88512732
67DYRK30.87455449
68MKNK10.84404866
69PRKCE0.81909952
70CDK80.78472980
71EPHB20.77434224
72MAP4K10.75201228
73PRKCG0.74135126
74JAK30.73115280
75CSF1R0.72646447
76STK380.72607120
77PRKD30.71197884
78BCR0.71116567
79PKN10.70172004
80DYRK1A0.67767224
81EIF2AK20.67742968
82DYRK1B0.66559690
83IKBKB0.66223007
84PAK30.65271476
85GRK10.64994754
86NTRK30.62491481
87EPHA40.61703051
88TBK10.61313828
89PINK10.60589011
90SGK30.60367275
91LYN0.59759407
92CDK30.59557860
93FGFR20.59236653
94BMX0.57716938
95PRKCQ0.56593111
96PIM10.56449066
97PLK40.54258894
98ATR0.53355089
99PRKACA0.53052394
100PHKG10.52528369
101PHKG20.52528369
102NME10.52294610
103NTRK20.52147818
104DAPK20.52055881
105CSNK1A10.50182784
106RPS6KA50.49014610
107CAMK2A0.48884618
108MAP3K120.48577844
109CAMK1G0.48205889
110NEK20.47905573
111CDK70.46503930
112CSNK1G20.45384895
113MYLK0.44398911
114CDK90.44181357
115MAPK110.43730489
116BMPR1B0.43391961
117TRIM280.43209440
118STK38L0.41963414
119SYK0.41246039
120MAPK130.40600785
121PRKCA0.40190895
122MAP2K70.39400221
123TYK20.38535403
124CSNK1G30.37768736
125MAPK70.37663293
126PRPF4B0.37192063
127BRD40.36336246
128MAPKAPK50.36178454
129STK30.36130347
130PRKCD0.35576482
131NEK60.35212695
132PRKAA20.34913163
133HCK0.33822582
134MATK0.33782571
135EPHB10.33700146
136LCK0.33488717
137MAPK40.33475516
138ADRBK20.32925425
139FER0.32402912
140SGK10.32288168
141CHUK0.32045184
142ZAK0.31841181
143CDK190.31827468
144EPHA20.30461617
145GSK3A0.29684951
146BMPR20.29282976
147BRSK20.29049045
148CSK0.28406851
149AURKA0.28301397
150STK110.27991127
151RPS6KC10.27989366
152RPS6KL10.27989366
153PLK30.27824926
154PRKCZ0.26773272
155PRKG10.26729350
156EPHA30.26186194
157MAP3K70.24553365
158RPS6KB10.23531408
159TIE10.23292344
160MAP2K60.23247114
161ZAP700.23215187
162CAMK10.23141015

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005113.69675050
2Oxidative phosphorylation_Homo sapiens_hsa001902.91721621
3Pentose and glucuronate interconversions_Homo sapiens_hsa000402.73848514
4Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.64424606
5Glycosaminoglycan degradation_Homo sapiens_hsa005312.56333441
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.51201685
7Propanoate metabolism_Homo sapiens_hsa006402.36435917
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.33777634
9Caffeine metabolism_Homo sapiens_hsa002322.33349804
10Huntingtons disease_Homo sapiens_hsa050162.30214910
11Fanconi anemia pathway_Homo sapiens_hsa034602.12871588
12Sphingolipid metabolism_Homo sapiens_hsa006002.12128207
13Parkinsons disease_Homo sapiens_hsa050122.09074553
14Vitamin digestion and absorption_Homo sapiens_hsa049772.03635710
15Cyanoamino acid metabolism_Homo sapiens_hsa004601.99772323
16Arachidonic acid metabolism_Homo sapiens_hsa005901.96250731
17Protein digestion and absorption_Homo sapiens_hsa049741.90200767
18Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.87008279
19Nitrogen metabolism_Homo sapiens_hsa009101.86359782
20Protein export_Homo sapiens_hsa030601.85593147
21Glutathione metabolism_Homo sapiens_hsa004801.83018079
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.82707091
23Homologous recombination_Homo sapiens_hsa034401.75102189
24Peroxisome_Homo sapiens_hsa041461.74988095
25Primary bile acid biosynthesis_Homo sapiens_hsa001201.68883697
26Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.64013254
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.62509237
28Maturity onset diabetes of the young_Homo sapiens_hsa049501.59828516
29Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.54711372
30Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.53775398
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.53203654
32Pyruvate metabolism_Homo sapiens_hsa006201.53115055
33Fatty acid degradation_Homo sapiens_hsa000711.52531075
34Histidine metabolism_Homo sapiens_hsa003401.51596330
35Mineral absorption_Homo sapiens_hsa049781.49960255
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.47490718
37Lysosome_Homo sapiens_hsa041421.46864866
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.44418180
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.41067795
40Retinol metabolism_Homo sapiens_hsa008301.37863607
41Alzheimers disease_Homo sapiens_hsa050101.34563206
42Butanoate metabolism_Homo sapiens_hsa006501.30642807
43Lysine degradation_Homo sapiens_hsa003101.30376009
44SNARE interactions in vesicular transport_Homo sapiens_hsa041301.29850487
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28457807
46Nicotine addiction_Homo sapiens_hsa050331.27381453
47Phototransduction_Homo sapiens_hsa047441.26666727
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.25733983
49Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.24515931
50Tyrosine metabolism_Homo sapiens_hsa003501.20988397
51Regulation of autophagy_Homo sapiens_hsa041401.18169458
52RNA polymerase_Homo sapiens_hsa030201.17110219
53Fatty acid metabolism_Homo sapiens_hsa012121.15912055
54Sulfur metabolism_Homo sapiens_hsa009201.15842215
55Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.13529325
56beta-Alanine metabolism_Homo sapiens_hsa004101.13509327
57Cardiac muscle contraction_Homo sapiens_hsa042601.13127199
58NF-kappa B signaling pathway_Homo sapiens_hsa040641.09824073
59Renin-angiotensin system_Homo sapiens_hsa046141.09687587
60Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.09267975
61Malaria_Homo sapiens_hsa051441.09094004
62Collecting duct acid secretion_Homo sapiens_hsa049661.07628446
63DNA replication_Homo sapiens_hsa030301.06998661
64Olfactory transduction_Homo sapiens_hsa047401.06671359
65Measles_Homo sapiens_hsa051621.05140680
66N-Glycan biosynthesis_Homo sapiens_hsa005101.03304000
67Glycerolipid metabolism_Homo sapiens_hsa005611.00765584
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.99011318
69Pentose phosphate pathway_Homo sapiens_hsa000300.96355206
70Leishmaniasis_Homo sapiens_hsa051400.93918717
71PPAR signaling pathway_Homo sapiens_hsa033200.93615602
72Tryptophan metabolism_Homo sapiens_hsa003800.93377535
73Ovarian steroidogenesis_Homo sapiens_hsa049130.89857217
74Ether lipid metabolism_Homo sapiens_hsa005650.89471124
75Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89096233
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.88054857
77ABC transporters_Homo sapiens_hsa020100.86120693
78Steroid biosynthesis_Homo sapiens_hsa001000.86010283
79Taste transduction_Homo sapiens_hsa047420.85136692
80Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.84568331
81Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.84125830
82Serotonergic synapse_Homo sapiens_hsa047260.81515435
83Intestinal immune network for IgA production_Homo sapiens_hsa046720.80461534
84Toll-like receptor signaling pathway_Homo sapiens_hsa046200.79427593
85Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78358260
86Osteoclast differentiation_Homo sapiens_hsa043800.76304766
87Basal transcription factors_Homo sapiens_hsa030220.75227648
88Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.72604506
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72544122
90Phenylalanine metabolism_Homo sapiens_hsa003600.71090081
91Asthma_Homo sapiens_hsa053100.70116064
92Purine metabolism_Homo sapiens_hsa002300.69939081
93Hematopoietic cell lineage_Homo sapiens_hsa046400.69666096
94Transcriptional misregulation in cancer_Homo sapiens_hsa052020.66285274
95Rheumatoid arthritis_Homo sapiens_hsa053230.66033069
96Steroid hormone biosynthesis_Homo sapiens_hsa001400.65201525
97Proteasome_Homo sapiens_hsa030500.64141203
98Jak-STAT signaling pathway_Homo sapiens_hsa046300.63907339
99RNA degradation_Homo sapiens_hsa030180.63845533
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.63276072
101Type I diabetes mellitus_Homo sapiens_hsa049400.61848995
102Herpes simplex infection_Homo sapiens_hsa051680.59910773
103RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.59258818
104Selenocompound metabolism_Homo sapiens_hsa004500.58246829
105Metabolic pathways_Homo sapiens_hsa011000.56836586
106Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.56631186
107Insulin secretion_Homo sapiens_hsa049110.56587046
108Tuberculosis_Homo sapiens_hsa051520.55888135
109Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.55231810
110Morphine addiction_Homo sapiens_hsa050320.55194848
111Starch and sucrose metabolism_Homo sapiens_hsa005000.52765039
112Fructose and mannose metabolism_Homo sapiens_hsa000510.52165678
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51890175
114Glutamatergic synapse_Homo sapiens_hsa047240.50838160
115Cocaine addiction_Homo sapiens_hsa050300.50766436
116Linoleic acid metabolism_Homo sapiens_hsa005910.50648692
117Base excision repair_Homo sapiens_hsa034100.49530302
118Thyroid hormone synthesis_Homo sapiens_hsa049180.49255458
119Sulfur relay system_Homo sapiens_hsa041220.49164126
120Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.48017964
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.47519961
122Chemical carcinogenesis_Homo sapiens_hsa052040.45569923
123Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.42411360
124Primary immunodeficiency_Homo sapiens_hsa053400.40989992
125ECM-receptor interaction_Homo sapiens_hsa045120.40858054
126Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40457335
127Circadian entrainment_Homo sapiens_hsa047130.39674903
128Fatty acid elongation_Homo sapiens_hsa000620.39390229
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38524829
130Salivary secretion_Homo sapiens_hsa049700.38337476
131Pyrimidine metabolism_Homo sapiens_hsa002400.38202534
132Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.37525142
133Hedgehog signaling pathway_Homo sapiens_hsa043400.36659890
134Legionellosis_Homo sapiens_hsa051340.36644886
135GABAergic synapse_Homo sapiens_hsa047270.36340331
136Calcium signaling pathway_Homo sapiens_hsa040200.35882068
137Folate biosynthesis_Homo sapiens_hsa007900.34983130
138Autoimmune thyroid disease_Homo sapiens_hsa053200.34890001
139Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.34813402
140Bile secretion_Homo sapiens_hsa049760.34288203
141Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.34012985
142Basal cell carcinoma_Homo sapiens_hsa052170.33633668
143Phagosome_Homo sapiens_hsa041450.33306157
144Ribosome_Homo sapiens_hsa030100.32550206
145Allograft rejection_Homo sapiens_hsa053300.32381071
146Non-homologous end-joining_Homo sapiens_hsa034500.30167279
147Fat digestion and absorption_Homo sapiens_hsa049750.28805024

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