GLG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)3.72895659
2sodium ion export (GO:0071436)3.72204247
3cytoskeletal anchoring at plasma membrane (GO:0007016)3.69666373
4layer formation in cerebral cortex (GO:0021819)3.64488619
5synaptic vesicle maturation (GO:0016188)3.53654586
6plasma membrane repair (GO:0001778)3.47096677
7regulation of short-term neuronal synaptic plasticity (GO:0048172)3.45042461
8cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.44693308
9chondrocyte proliferation (GO:0035988)3.35311141
10cell communication by electrical coupling (GO:0010644)3.31039227
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.29112125
12presynaptic membrane assembly (GO:0097105)3.19848683
13cellular potassium ion homeostasis (GO:0030007)3.16725953
14collagen fibril organization (GO:0030199)3.16720050
15paraxial mesoderm development (GO:0048339)3.15271111
16establishment of nucleus localization (GO:0040023)3.13485465
17cell adhesion mediated by integrin (GO:0033627)3.04807026
18negative regulation of chondrocyte differentiation (GO:0032331)3.04319723
19COPI coating of Golgi vesicle (GO:0048205)3.04092943
20Golgi transport vesicle coating (GO:0048200)3.04092943
21embryonic retina morphogenesis in camera-type eye (GO:0060059)2.98221430
22calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.96502451
23activation of protein kinase A activity (GO:0034199)2.93095663
24fibroblast migration (GO:0010761)2.90974060
25insulin-like growth factor receptor signaling pathway (GO:0048009)2.90731713
26COPII vesicle coating (GO:0048208)2.88457635
27vocalization behavior (GO:0071625)2.87338837
28negative regulation of axon extension involved in axon guidance (GO:0048843)2.86315070
29skin morphogenesis (GO:0043589)2.82443634
30regulation of axon guidance (GO:1902667)2.77333445
31glomerular visceral epithelial cell development (GO:0072015)2.76357638
32maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.75603767
33negative chemotaxis (GO:0050919)2.75305364
34negative regulation of axon guidance (GO:1902668)2.75189889
35membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.73388886
36retina vasculature morphogenesis in camera-type eye (GO:0061299)2.72743979
37G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.72187106
38positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.72155277
39proline transport (GO:0015824)2.72102396
40exploration behavior (GO:0035640)2.71744146
41dendritic spine morphogenesis (GO:0060997)2.71165895
42protein retention in ER lumen (GO:0006621)2.70786597
43regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.70449978
44negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.70419095
45regulation of extracellular matrix disassembly (GO:0010715)2.69133525
46presynaptic membrane organization (GO:0097090)2.65347587
47dendrite morphogenesis (GO:0048813)2.65143948
48potassium ion import (GO:0010107)2.64603718
49regulation of synaptic vesicle exocytosis (GO:2000300)2.61112448
50regulation of clathrin-mediated endocytosis (GO:2000369)2.61091874
51synaptic vesicle docking involved in exocytosis (GO:0016081)2.59794852
52neuromuscular process controlling balance (GO:0050885)2.59728153
53innervation (GO:0060384)2.58800944
54embryonic foregut morphogenesis (GO:0048617)2.58431865
55synaptic vesicle exocytosis (GO:0016079)2.58304107
56vesicle transport along microtubule (GO:0047496)2.58276848
57pyrimidine nucleobase catabolic process (GO:0006208)2.57354660
58stress fiber assembly (GO:0043149)2.57223918
59cerebellar Purkinje cell layer development (GO:0021680)2.57014993
60membrane repolarization (GO:0086009)2.56456405
61regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.54859910
62membrane repolarization during action potential (GO:0086011)2.53932674
63protein localization to endosome (GO:0036010)2.52840196
64regulation of ARF protein signal transduction (GO:0032012)2.52823744
65regulation of non-canonical Wnt signaling pathway (GO:2000050)2.52625084
66axonal fasciculation (GO:0007413)2.52446396
67mesenchymal-epithelial cell signaling (GO:0060638)2.51813264
68glutamate secretion (GO:0014047)2.49633083
69cell migration involved in sprouting angiogenesis (GO:0002042)2.48994166
70protein heterotrimerization (GO:0070208)2.48423934
71regulation of synapse structural plasticity (GO:0051823)2.47373324
72cell communication involved in cardiac conduction (GO:0086065)2.46334831
73L-serine transport (GO:0015825)2.44717448
74cytoplasmic mRNA processing body assembly (GO:0033962)2.44488566
75regulation of glutamate receptor signaling pathway (GO:1900449)2.44013848
76hemidesmosome assembly (GO:0031581)2.43394639
77dorsal/ventral axis specification (GO:0009950)2.43091076
78sequestering of extracellular ligand from receptor (GO:0035581)2.41237285
79urinary tract smooth muscle contraction (GO:0014848)2.41224240
80nerve growth factor signaling pathway (GO:0038180)2.40035270
81neuron recognition (GO:0008038)2.39776347
82kidney morphogenesis (GO:0060993)2.37994514
83postsynaptic membrane organization (GO:0001941)2.36879111
84cerebellar Purkinje cell differentiation (GO:0021702)2.36630250
85mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.36498832
86craniofacial suture morphogenesis (GO:0097094)2.34834058
87membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.33763289
88positive regulation of fibroblast migration (GO:0010763)2.33235946
89axon extension (GO:0048675)2.33091261
90protein localization to cell surface (GO:0034394)2.32988261
91mating behavior (GO:0007617)2.32831955
92endodermal cell differentiation (GO:0035987)2.32573112
93G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.32534240
94positive regulation of hormone biosynthetic process (GO:0046886)2.32228590
95positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.32092692
96glomerular epithelial cell development (GO:0072310)2.31585143
97regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.31295859
98ionotropic glutamate receptor signaling pathway (GO:0035235)2.29827231
99cell migration in hindbrain (GO:0021535)2.29228767
100suckling behavior (GO:0001967)2.28477544
101potassium ion homeostasis (GO:0055075)2.28360274
102negative regulation of osteoblast proliferation (GO:0033689)2.27707671
103positive regulation of synapse maturation (GO:0090129)2.27413420
104glial cell proliferation (GO:0014009)2.26787620
105regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.26609940
106positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.26226133
107neuromuscular junction development (GO:0007528)2.25654971
108adherens junction assembly (GO:0034333)2.25346146
109positive regulation of axon extension (GO:0045773)2.24754461
110protein targeting to plasma membrane (GO:0072661)2.24745310
111cellular sodium ion homeostasis (GO:0006883)2.24625813
112neuron projection extension involved in neuron projection guidance (GO:1902284)2.24609050
113axon extension involved in axon guidance (GO:0048846)2.24609050
114glomerular basement membrane development (GO:0032836)2.23753324
115regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.23313638
116cardiac myofibril assembly (GO:0055003)2.23209179
117negative regulation of potassium ion transmembrane transport (GO:1901380)2.22823020
118protein targeting to Golgi (GO:0000042)2.22645008
119planar cell polarity pathway involved in neural tube closure (GO:0090179)2.22492720
120clathrin coat assembly (GO:0048268)2.22043093
121organelle transport along microtubule (GO:0072384)2.21521773
122substrate adhesion-dependent cell spreading (GO:0034446)2.21366265
123protein hydroxylation (GO:0018126)2.21009505
124peptidyl-proline hydroxylation (GO:0019511)2.20630532
125regulation of long-term neuronal synaptic plasticity (GO:0048169)2.20428508
126regulation of transforming growth factor beta2 production (GO:0032909)2.20428321
127negative regulation of catenin import into nucleus (GO:0035414)2.19912327
128neurotransmitter secretion (GO:0007269)2.19427971
129neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.18370595
130regulation of neuronal synaptic plasticity (GO:0048168)2.17956304
131* regulation of chondrocyte differentiation (GO:0032330)2.17883671
132establishment of protein localization to Golgi (GO:0072600)2.17339360
133inner ear receptor cell development (GO:0060119)2.17116239
134hippo signaling (GO:0035329)2.16476581
135vesicle coating (GO:0006901)2.15779341
136relaxation of cardiac muscle (GO:0055119)2.15473358
137regulation of axon extension involved in axon guidance (GO:0048841)2.15222360
138regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.14757395
139regulation of establishment of planar polarity (GO:0090175)2.13086894
140basement membrane organization (GO:0071711)2.12841155
141regulation of potassium ion transmembrane transport (GO:1901379)2.12670364
142organ induction (GO:0001759)2.12603542
143Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.12136954
144camera-type eye morphogenesis (GO:0048593)2.12084972
145convergent extension (GO:0060026)2.11998231
146gonadal mesoderm development (GO:0007506)2.11996779
147regulation of dendritic spine morphogenesis (GO:0061001)2.11738126
148positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.11469257
149regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.10810123
150regulation of potassium ion transmembrane transporter activity (GO:1901016)2.10589153
151morphogenesis of an epithelial sheet (GO:0002011)2.09981455
152positive regulation of potassium ion transmembrane transport (GO:1901381)2.09554005
153positive regulation of dendritic spine morphogenesis (GO:0061003)2.09494597
154heparan sulfate proteoglycan metabolic process (GO:0030201)2.09482913
155heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.09453929
156regulation of synaptic vesicle transport (GO:1902803)2.08267712
157neuron cell-cell adhesion (GO:0007158)2.08098725
158regulation of membrane repolarization (GO:0060306)2.07414626
159response to follicle-stimulating hormone (GO:0032354)2.07087338
160glucocorticoid receptor signaling pathway (GO:0042921)2.06669605
161glutamate receptor signaling pathway (GO:0007215)2.06542209
162regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.06007273
163semaphorin-plexin signaling pathway (GO:0071526)2.05460571
164neuron projection extension (GO:1990138)2.05377750
165regulation of hippo signaling (GO:0035330)2.05117772
166substrate-dependent cell migration (GO:0006929)2.05012113
167olfactory bulb development (GO:0021772)2.04241682
168appendage development (GO:0048736)2.04196791
169limb development (GO:0060173)2.04196791
170retinal ganglion cell axon guidance (GO:0031290)2.03794178
171retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.03685028
172lymphangiogenesis (GO:0001946)2.03147174
173positive regulation of smoothened signaling pathway (GO:0045880)2.02329720
174positive regulation of dendrite morphogenesis (GO:0050775)2.02308834
175developmental cell growth (GO:0048588)2.01870358
176synapse assembly (GO:0007416)2.01839715
177developmental growth involved in morphogenesis (GO:0060560)2.01646905
178negative regulation of cartilage development (GO:0061037)2.00883951
179polarized epithelial cell differentiation (GO:0030859)1.99946069
180desmosome organization (GO:0002934)1.99430563
181negative regulation of hormone biosynthetic process (GO:0032353)1.98188855
182collagen metabolic process (GO:0032963)1.97564048
183cell proliferation involved in kidney development (GO:0072111)1.97548466
184bone remodeling (GO:0046849)1.97543408
185nucleobase catabolic process (GO:0046113)1.96356780
186ectodermal placode formation (GO:0060788)1.95717090
187mesenchymal cell proliferation (GO:0010463)1.95226964
188face morphogenesis (GO:0060325)1.94651848

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.61589699
2EZH2_22144423_ChIP-Seq_EOC_Human3.36706437
3PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.65386849
4SALL1_21062744_ChIP-ChIP_HESCs_Human2.52522467
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.39096556
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.28251077
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.28251077
8DROSHA_22980978_ChIP-Seq_HELA_Human2.26392058
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.17881672
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.13580286
11WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.12129963
12EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.10246938
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.99960363
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.99365235
15MTF2_20144788_ChIP-Seq_MESCs_Mouse1.97073780
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.96313770
17ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94037963
18TRIM28_21343339_ChIP-Seq_HEK293_Human1.93485556
19JARID2_20075857_ChIP-Seq_MESCs_Mouse1.88856604
20TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.88355292
21HIF1A_21447827_ChIP-Seq_MCF-7_Human1.86182028
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.82518001
23RARB_27405468_Chip-Seq_BRAIN_Mouse1.81281473
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.80647384
25NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.79697213
26GBX2_23144817_ChIP-Seq_PC3_Human1.79333331
27STAT6_21828071_ChIP-Seq_BEAS2B_Human1.78866779
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.76962205
29SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.75849740
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.75680567
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.74705803
32KDM2B_26808549_Chip-Seq_K562_Human1.72684190
33ZFP281_18757296_ChIP-ChIP_E14_Mouse1.71776691
34EZH2_27304074_Chip-Seq_ESCs_Mouse1.70885209
35EP300_21415370_ChIP-Seq_HL-1_Mouse1.65958201
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.65821808
37EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.65431879
38* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.64897490
39DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.62138173
40NRF2_20460467_ChIP-Seq_MEFs_Mouse1.59821071
41NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.59821071
42CDX2_19796622_ChIP-Seq_MESCs_Mouse1.57425469
43FOXA2_19822575_ChIP-Seq_HepG2_Human1.57073842
44* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.56565578
45WT1_25993318_ChIP-Seq_PODOCYTE_Human1.55417356
46CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.53776659
47SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53677626
48KDM2B_26808549_Chip-Seq_SUP-B15_Human1.53675208
49CJUN_26792858_Chip-Seq_BT549_Human1.52763684
50TP53_16413492_ChIP-PET_HCT116_Human1.51992102
51EZH2_27294783_Chip-Seq_ESCs_Mouse1.51009142
52OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.49932942
53ZFP281_27345836_Chip-Seq_ESCs_Mouse1.47433808
54SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.45420407
55TBX3_20139965_ChIP-Seq_ESCs_Mouse1.44861802
56TBX3_20139965_ChIP-Seq_MESCs_Mouse1.44824935
57SUZ12_27294783_Chip-Seq_ESCs_Mouse1.44506662
58* BRD4_25478319_ChIP-Seq_HGPS_Human1.44331491
59AR_21572438_ChIP-Seq_LNCaP_Human1.43715388
60NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.42029244
61POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37260661
62IKZF1_21737484_ChIP-ChIP_HCT116_Human1.36964556
63TCF4_18268006_ChIP-ChIP_LS174T_Human1.34863147
64VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.34674376
65* AHR_22903824_ChIP-Seq_MCF-7_Human1.34356854
66* KDM2B_26808549_Chip-Seq_DND41_Human1.32144208
67ESR2_21235772_ChIP-Seq_MCF-7_Human1.31956163
68NR3C1_23031785_ChIP-Seq_PC12_Mouse1.30955828
69STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.30724295
70EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.30182973
71MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29734500
72ERG_21242973_ChIP-ChIP_JURKAT_Human1.29168390
73SMAD_19615063_ChIP-ChIP_OVARY_Human1.27403275
74* ARNT_22903824_ChIP-Seq_MCF-7_Human1.27206340
75MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25455112
76AR_19668381_ChIP-Seq_PC3_Human1.24284438
77P300_19829295_ChIP-Seq_ESCs_Human1.24233368
78TAF15_26573619_Chip-Seq_HEK293_Human1.24061286
79SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24015076
80CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.23577372
81WT1_19549856_ChIP-ChIP_CCG9911_Human1.23222465
82SOX9_24532713_ChIP-Seq_HFSC_Mouse1.22946811
83* KDM2B_26808549_Chip-Seq_JURKAT_Human1.22845001
84KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.21484631
85* ISL1_27105846_Chip-Seq_CPCs_Mouse1.20854985
86ESR1_20079471_ChIP-ChIP_T-47D_Human1.20564349
87GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.20258092
88REST_21632747_ChIP-Seq_MESCs_Mouse1.19645059
89ZNF274_21170338_ChIP-Seq_K562_Hela1.19617996
90P300_27058665_Chip-Seq_ZR-75-30cells_Human1.19157599
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19074090
92ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.17365019
93SOX2_21211035_ChIP-Seq_LN229_Gbm1.17200226
94RING1B_27294783_Chip-Seq_ESCs_Mouse1.16681184
95SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.16558753
96SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.15490948
97SMAD3_21741376_ChIP-Seq_EPCs_Human1.15488382
98CTBP2_25329375_ChIP-Seq_LNCAP_Human1.15267494
99RING1B_27294783_Chip-Seq_NPCs_Mouse1.15154839
100NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.14912241
101IGF1R_20145208_ChIP-Seq_DFB_Human1.14672173
102* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14411688
103YAP1_20516196_ChIP-Seq_MESCs_Mouse1.13663094
104SMAD4_21799915_ChIP-Seq_A2780_Human1.13387889
105PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.12683338
106CLOCK_20551151_ChIP-Seq_293T_Human1.12118705
107GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11332518
108MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.10893362
109KDM2B_26808549_Chip-Seq_REH_Human1.08443949
110BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07444832
111PIAS1_25552417_ChIP-Seq_VCAP_Human1.07091697
112RARG_19884340_ChIP-ChIP_MEFs_Mouse1.06427769
113SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.05753768
114PCGF2_27294783_Chip-Seq_ESCs_Mouse1.05466763
115SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03724062
116BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.03697091
117RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.03681745
118SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.03615991
119RXR_22108803_ChIP-Seq_LS180_Human1.03415062
120AR_25329375_ChIP-Seq_VCAP_Human1.02396044
121TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.01735307
122REST_18959480_ChIP-ChIP_MESCs_Mouse1.01390185
123CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.01337585
124* TCF4_23295773_ChIP-Seq_U87_Human1.01241492
125PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.99987930
126PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99546460
127FLI1_27457419_Chip-Seq_LIVER_Mouse0.99466847
128ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.99385768
129RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99325631
130STAT3_23295773_ChIP-Seq_U87_Human0.98523742
131SMAD4_21741376_ChIP-Seq_HESCs_Human0.98219069
132SMAD3_21741376_ChIP-Seq_HESCs_Human0.97981327
133FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.97747880
134FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97541163
135TP63_17297297_ChIP-ChIP_HaCaT_Human0.97487988
136TBX20_22328084_ChIP-Seq_HEART_Mouse0.96887868
137TBX20_22080862_ChIP-Seq_HEART_Mouse0.96887868
138EGR1_19374776_ChIP-ChIP_THP-1_Human0.96836514
139FOXO3_23340844_ChIP-Seq_DLD1_Human0.96701910
140NANOG_18555785_Chip-Seq_ESCs_Mouse0.96647613
141SOX9_26525672_Chip-Seq_HEART_Mouse0.95788498
142KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.95773083
143PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.95507003
144HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95368285
145AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94804102
146DNAJC2_21179169_ChIP-ChIP_NT2_Human0.94028635
147TP53_18474530_ChIP-ChIP_U2OS_Human0.93811732

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.84083251
2MP0008438_abnormal_cutaneous_collagen3.10875063
3MP0005623_abnormal_meninges_morphology2.87312421
4MP0003283_abnormal_digestive_organ2.63813650
5MP0000569_abnormal_digit_pigmentation2.60332855
6MP0005257_abnormal_intraocular_pressure2.52031703
7MP0003705_abnormal_hypodermis_morpholog2.49910797
8MP0004858_abnormal_nervous_system2.41830685
9MP0003635_abnormal_synaptic_transmissio2.28686216
10MP0000751_myopathy2.17699516
11MP0004272_abnormal_basement_membrane2.15062049
12MP0010030_abnormal_orbit_morphology2.01286363
13MP0004270_analgesia1.99663699
14MP0002254_reproductive_system_inflammat1.90013410
15MP0003045_fibrosis1.89034104
16MP0010368_abnormal_lymphatic_system1.87818717
17MP0001299_abnormal_eye_distance/1.87266752
18MP0002909_abnormal_adrenal_gland1.78043637
19MP0010234_abnormal_vibrissa_follicle1.77325138
20MP0005503_abnormal_tendon_morphology1.76939390
21MP0004084_abnormal_cardiac_muscle1.73619325
22MP0005275_abnormal_skin_tensile1.72956993
23MP0003122_maternal_imprinting1.71673246
24MP0000566_synostosis1.69622445
25MP0001958_emphysema1.69490753
26MP0000013_abnormal_adipose_tissue1.63928483
27MP0002063_abnormal_learning/memory/cond1.62433201
28MP0003300_gastrointestinal_ulcer1.60785001
29MP0003279_aneurysm1.55840908
30MP0004233_abnormal_muscle_weight1.55196684
31MP0003329_amyloid_beta_deposits1.54939129
32MP0003121_genomic_imprinting1.54732434
33MP0002837_dystrophic_cardiac_calcinosis1.52512662
34MP0005076_abnormal_cell_differentiation1.51295777
35MP0002064_seizures1.49372722
36MP0003091_abnormal_cell_migration1.45161565
37MP0003880_abnormal_central_pattern1.44914140
38MP0003941_abnormal_skin_development1.42994159
39MP0002938_white_spotting1.42958030
40MP0000537_abnormal_urethra_morphology1.42688261
41MP0000767_abnormal_smooth_muscle1.42410885
42MP0002233_abnormal_nose_morphology1.41514359
43MP0002877_abnormal_melanocyte_morpholog1.41511994
44MP0009745_abnormal_behavioral_response1.39606775
45MP0009046_muscle_twitch1.38777607
46MP0003937_abnormal_limbs/digits/tail_de1.34474135
47MP0008961_abnormal_basal_metabolism1.31493786
48MP0001984_abnormal_olfaction1.31183272
49MP0009384_cardiac_valve_regurgitation1.30734112
50MP0004145_abnormal_muscle_electrophysio1.28494166
51MP0001849_ear_inflammation1.28360321
52MP0003566_abnormal_cell_adhesion1.28132920
53MP0002896_abnormal_bone_mineralization1.27710839
54MP0005508_abnormal_skeleton_morphology1.26390007
55MP0003950_abnormal_plasma_membrane1.24925037
56MP0002295_abnormal_pulmonary_circulatio1.24910235
57MP0005409_darkened_coat_color1.24468380
58MP0002572_abnormal_emotion/affect_behav1.22119398
59* MP0003755_abnormal_palate_morphology1.19909290
60MP0000003_abnormal_adipose_tissue1.19860550
61MP0002060_abnormal_skin_morphology1.19304341
62MP0000778_abnormal_nervous_system1.17946864
63MP0000428_abnormal_craniofacial_morphol1.17838875
64* MP0009780_abnormal_chondrocyte_physiolo1.17456612
65MP0000534_abnormal_ureter_morphology1.17023287
66MP0002108_abnormal_muscle_morphology1.16388244
67MP0000432_abnormal_head_morphology1.15642406
68MP0008569_lethality_at_weaning1.14759618
69MP0004036_abnormal_muscle_relaxation1.14726409
70MP0002932_abnormal_joint_morphology1.13970108
71MP0004885_abnormal_endolymph1.13733576
72MP0002734_abnormal_mechanical_nocicepti1.13297045
73MP0005248_abnormal_Harderian_gland1.12603256
74MP0000733_abnormal_muscle_development1.11172803
75MP0004811_abnormal_neuron_physiology1.10555739
76MP0004215_abnormal_myocardial_fiber1.10542758
77MP0001915_intracranial_hemorrhage1.10514689
78MP0003385_abnormal_body_wall1.09943009
79MP0004087_abnormal_muscle_fiber1.09052075
80MP0005187_abnormal_penis_morphology1.08642692
81MP0001529_abnormal_vocalization1.08610344
82MP0003935_abnormal_craniofacial_develop1.07739743
83MP0000747_muscle_weakness1.07408348
84MP0002234_abnormal_pharynx_morphology1.04457217
85* MP0002116_abnormal_craniofacial_bone1.03748847
86MP0001440_abnormal_grooming_behavior1.03271404
87MP0003634_abnormal_glial_cell1.02373300
88MP0004484_altered_response_of1.01334958
89MP0002184_abnormal_innervation1.00795793
90MP0002272_abnormal_nervous_system1.00410561
91MP0001486_abnormal_startle_reflex0.99654259
92MP0001968_abnormal_touch/_nociception0.98200693
93MP0000955_abnormal_spinal_cord0.97514061
94MP0001270_distended_abdomen0.96222476
95MP0010678_abnormal_skin_adnexa0.94780132
96MP0004130_abnormal_muscle_cell0.94184487
97MP0006138_congestive_heart_failure0.93964550
98MP0002733_abnormal_thermal_nociception0.93714456
99MP0004133_heterotaxia0.93619425
100MP0006054_spinal_hemorrhage0.92587772
101MP0004085_abnormal_heartbeat0.91586958
102MP0000762_abnormal_tongue_morphology0.90699988
103MP0003115_abnormal_respiratory_system0.89467089
104MP0010352_gastrointestinal_tract_polyps0.89446399
105MP0003123_paternal_imprinting0.86876915
106MP0002168_other_aberrant_phenotype0.86858185
107MP0002067_abnormal_sensory_capabilities0.85787782
108MP0010630_abnormal_cardiac_muscle0.85639930
109MP0001177_atelectasis0.85292628
110MP0002089_abnormal_postnatal_growth/wei0.85189067
111MP0005171_absent_coat_pigmentation0.84869241
112MP0001348_abnormal_lacrimal_gland0.83996855
113MP0002972_abnormal_cardiac_muscle0.83673104
114MP0003172_abnormal_lysosome_physiology0.83574788
115MP0003942_abnormal_urinary_system0.83018837
116MP0002697_abnormal_eye_size0.82780089
117MP0003890_abnormal_embryonic-extraembry0.82649551
118MP0003861_abnormal_nervous_system0.82277820
119MP0002882_abnormal_neuron_morphology0.82043557
120MP0003690_abnormal_glial_cell0.81422847
121MP0001286_abnormal_eye_development0.81086445
122MP0003632_abnormal_nervous_system0.80494783
123MP0001970_abnormal_pain_threshold0.79266659
124MP0002152_abnormal_brain_morphology0.79069166
125MP0002735_abnormal_chemical_nociception0.79037061
126MP0003787_abnormal_imprinting0.78160317
127MP0004134_abnormal_chest_morphology0.77611615
128MP0005375_adipose_tissue_phenotype0.77567790
129MP0005620_abnormal_muscle_contractility0.77398246
130MP0001501_abnormal_sleep_pattern0.77232631
131MP0002751_abnormal_autonomic_nervous0.77024521
132MP0003137_abnormal_impulse_conducting0.76859116
133MP0005023_abnormal_wound_healing0.76502399
134MP0005394_taste/olfaction_phenotype0.76491599
135MP0005499_abnormal_olfactory_system0.76491599
136MP0008775_abnormal_heart_ventricle0.76311524
137MP0004924_abnormal_behavior0.75752105
138MP0005386_behavior/neurological_phenoty0.75752105
139MP0003633_abnormal_nervous_system0.75620104
140MP0000579_abnormal_nail_morphology0.75539522
141MP0004185_abnormal_adipocyte_glucose0.75359722
142MP0009250_abnormal_appendicular_skeleto0.72588946
143MP0000049_abnormal_middle_ear0.71553676
144MP0002092_abnormal_eye_morphology0.71354477
145* MP0002114_abnormal_axial_skeleton0.71123534
146MP0002109_abnormal_limb_morphology0.70350160
147MP0000462_abnormal_digestive_system0.68514663
148MP0002084_abnormal_developmental_patter0.66868725
149MP0000383_abnormal_hair_follicle0.66055759
150MP0000538_abnormal_urinary_bladder0.65826241
151MP0002925_abnormal_cardiovascular_devel0.65590350
152MP0001614_abnormal_blood_vessel0.65338454
153* MP0009703_decreased_birth_body0.65024053
154MP0000427_abnormal_hair_cycle0.64438002
155MP0002557_abnormal_social/conspecific_i0.64216955
156MP0000516_abnormal_urinary_system0.63733802
157MP0005367_renal/urinary_system_phenotyp0.63733802

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of dentin (HP:0010299)3.49256557
2Neonatal short-limb short stature (HP:0008921)3.48156306
3Shallow orbits (HP:0000586)3.43718761
4Protrusio acetabuli (HP:0003179)3.43462071
5Cerebral aneurysm (HP:0004944)3.43267384
6Broad metatarsal (HP:0001783)2.96283763
7Soft skin (HP:0000977)2.96207754
8Premature rupture of membranes (HP:0001788)2.84657313
9Macroorchidism (HP:0000053)2.69189151
10Ankle contracture (HP:0006466)2.67109332
11Bladder diverticulum (HP:0000015)2.55913764
12Action tremor (HP:0002345)2.45924615
13Focal seizures (HP:0007359)2.45730580
14Buphthalmos (HP:0000557)2.43897746
15Hyperacusis (HP:0010780)2.33437097
16Asymmetry of the thorax (HP:0001555)2.31668532
17Upper limb amyotrophy (HP:0009129)2.31592409
18Distal upper limb amyotrophy (HP:0007149)2.31592409
19Wide anterior fontanel (HP:0000260)2.29585989
20Bowel diverticulosis (HP:0005222)2.29374294
21Termporal pattern (HP:0011008)2.28143571
22Insidious onset (HP:0003587)2.28143571
23Supranuclear gaze palsy (HP:0000605)2.25329993
24Cerebral inclusion bodies (HP:0100314)2.24695773
25Aortic aneurysm (HP:0004942)2.23826302
26Arterial tortuosity (HP:0005116)2.17614226
27Visual hallucinations (HP:0002367)2.16934381
28Insomnia (HP:0100785)2.16409410
29Mitral valve prolapse (HP:0001634)2.16311370
30Aortic dissection (HP:0002647)2.16267567
31Mitral stenosis (HP:0001718)2.13167913
32Papilledema (HP:0001085)2.12418907
33Dilatation of the ascending aorta (HP:0005111)2.11303170
34Genu recurvatum (HP:0002816)2.10808861
35Atrophic scars (HP:0001075)2.09923854
36Increased variability in muscle fiber diameter (HP:0003557)2.09875166
37Aneurysm (HP:0002617)2.09745988
38Vascular tortuosity (HP:0004948)2.09740099
39Overgrowth (HP:0001548)2.09206227
40Hypoventilation (HP:0002791)2.09103828
41Hand muscle atrophy (HP:0009130)2.08977797
42Joint laxity (HP:0001388)2.04286649
43Follicular hyperkeratosis (HP:0007502)2.03510856
44Natal tooth (HP:0000695)2.02570546
45Broad palm (HP:0001169)2.01093711
46Lower limb amyotrophy (HP:0007210)1.97126939
47Subacute progressive viral hepatitis (HP:0006572)1.94987962
48Dysmetric saccades (HP:0000641)1.94490238
49Enlarged penis (HP:0000040)1.93815636
50Coronal craniosynostosis (HP:0004440)1.93617632
51Focal motor seizures (HP:0011153)1.93560174
52Peritonitis (HP:0002586)1.92958335
53Pointed chin (HP:0000307)1.92055539
54Lymphangioma (HP:0100764)1.90919180
55Wrist flexion contracture (HP:0001239)1.89713633
56Bronchomalacia (HP:0002780)1.86775864
57Ankyloglossia (HP:0010296)1.86503980
58Renal duplication (HP:0000075)1.86397771
59Elfin facies (HP:0004428)1.86308621
60Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.86032306
61Short 4th metacarpal (HP:0010044)1.86032306
62Flat cornea (HP:0007720)1.85091487
63Hemiplegia (HP:0002301)1.84271396
64Broad long bones (HP:0005622)1.83731382
65Pterygium (HP:0001059)1.83357040
66Mildly elevated creatine phosphokinase (HP:0008180)1.83323762
67Neoplasm of the heart (HP:0100544)1.82645064
68Fragile skin (HP:0001030)1.79785593
69Turricephaly (HP:0000262)1.79716301
70Myokymia (HP:0002411)1.79266193
71Deviation of the hallux (HP:0010051)1.79015818
72Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.78346079
73Urinary bladder sphincter dysfunction (HP:0002839)1.77419309
74Atonic seizures (HP:0010819)1.77343062
75Cutaneous finger syndactyly (HP:0010554)1.76729753
76Hyporeflexia of lower limbs (HP:0002600)1.76479893
77Mild short stature (HP:0003502)1.76366390
78Scapular winging (HP:0003691)1.75314354
79Thin bony cortex (HP:0002753)1.74942698
80Striae distensae (HP:0001065)1.74887705
81Abnormality of oral frenula (HP:0000190)1.74837113
82Advanced eruption of teeth (HP:0006288)1.74200768
83Vertebral arch anomaly (HP:0008438)1.74039658
84Aplasia involving bones of the upper limbs (HP:0009823)1.73430796
85Aplasia of the phalanges of the hand (HP:0009802)1.73430796
86Aplasia involving bones of the extremities (HP:0009825)1.73430796
87Abnormality of the lower motor neuron (HP:0002366)1.73364446
88Limited elbow extension (HP:0001377)1.72195490
89Hyperextensible skin (HP:0000974)1.72108424
90Biconcave vertebral bodies (HP:0004586)1.71789375
91Overriding aorta (HP:0002623)1.71765222
92Rapidly progressive (HP:0003678)1.71347610
93Breech presentation (HP:0001623)1.71147611
94Congenital glaucoma (HP:0001087)1.70052483
95Hallux valgus (HP:0001822)1.69939233
96Depression (HP:0000716)1.69764625
97Abnormal delivery (HP:0001787)1.69421480
98Narrow palate (HP:0000189)1.69151349
99Neurofibrillary tangles (HP:0002185)1.69131382
100Ulnar bowing (HP:0003031)1.69018857
101Difficulty running (HP:0009046)1.68925714
102Renovascular hypertension (HP:0100817)1.68730828
103Inguinal hernia (HP:0000023)1.66777210
104Broad phalanx (HP:0006009)1.66462760
105Sudden death (HP:0001699)1.66127232
106Broad ribs (HP:0000885)1.66092458
107Wormian bones (HP:0002645)1.66004227
108Hypoplastic ischia (HP:0003175)1.65609469
109Increased connective tissue (HP:0009025)1.65542690
110Hypercortisolism (HP:0001578)1.65530828
111Rhizomelia (HP:0008905)1.65451830
112Genetic anticipation (HP:0003743)1.65385435
113Aqueductal stenosis (HP:0002410)1.65333517
114Apathy (HP:0000741)1.65312960
115Abnormality of skeletal muscle fiber size (HP:0012084)1.65299253
116Truncal ataxia (HP:0002078)1.64780310
117Cervical subluxation (HP:0003308)1.64189719
118Flared iliac wings (HP:0002869)1.64110348
119Exostoses (HP:0100777)1.63919554
120Hepatoblastoma (HP:0002884)1.63695256
121Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.62745708
122Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.62524422
123Blue sclerae (HP:0000592)1.62520777
124Arnold-Chiari malformation (HP:0002308)1.62484726
125Abnormality of the 4th metacarpal (HP:0010012)1.61488822
126Hemiparesis (HP:0001269)1.61457953
127Microglossia (HP:0000171)1.60940360
128Spinal rigidity (HP:0003306)1.60465543
129Hypoplasia of the capital femoral epiphysis (HP:0003090)1.60183087
130Megalencephaly (HP:0001355)1.59914479
131Protruding ear (HP:0000411)1.59609225
132Resting tremor (HP:0002322)1.59539538
133Type 1 muscle fiber predominance (HP:0003803)1.59433492
134Astrocytoma (HP:0009592)1.59296221
135Abnormality of the astrocytes (HP:0100707)1.59296221
136Absent frontal sinuses (HP:0002688)1.58984579
137Abnormality of the acetabulum (HP:0003170)1.58481913
138Vitreoretinal degeneration (HP:0000655)1.58473398
139Dislocated radial head (HP:0003083)1.54832582
140Morphological abnormality of the middle ear (HP:0008609)1.54506990
141Hypoplasia of the odontoid process (HP:0003311)1.54275723
142Osteoarthritis (HP:0002758)1.54221144
143Limited hip movement (HP:0008800)1.53519489
144Trigonocephaly (HP:0000243)1.52899804
145Ovoid vertebral bodies (HP:0003300)1.50401643
146Coxa vara (HP:0002812)1.50396733
147Aortic regurgitation (HP:0001659)1.49767585
148Pulmonic stenosis (HP:0001642)1.49460539
149Broad thumb (HP:0011304)1.47337609
150Increased corneal curvature (HP:0100692)1.47161573
151Keratoconus (HP:0000563)1.47161573
152Renal hypoplasia (HP:0000089)1.47145360
153Abnormality of the humeroradial joint (HP:0100744)1.45718142
154Hypoplastic scapulae (HP:0000882)1.44533715
155Aplasia/Hypoplasia of the scapulae (HP:0006713)1.44533715
156Delayed gross motor development (HP:0002194)1.44420598
157Cutaneous syndactyly (HP:0012725)1.44386171
158Abnormality of the ischium (HP:0003174)1.44344045
159Abnormality of the radial head (HP:0003995)1.44157738
160Occipital encephalocele (HP:0002085)1.43813717
161Osteopenia (HP:0000938)1.43712765
162Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.43584666
163Skull defect (HP:0001362)1.43248197

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB32.94868289
2NTRK32.81914867
3MAP3K92.57017519
4PDGFRA2.44765518
5PKN22.43707144
6TNIK2.43252552
7FGFR42.29783318
8RIPK12.25313355
9NTRK12.24026522
10CASK2.22533581
11TTN2.19035457
12MET2.16970820
13PAK62.04473260
14DDR22.00670662
15BCR1.96297123
16KSR21.95768854
17PRKD31.82563306
18CAMK1G1.77491347
19DMPK1.75541296
20MAP3K41.75175015
21LMTK21.73513175
22SCYL21.70714869
23MAP3K21.65423313
24EPHA41.61638393
25RET1.53899525
26CAMKK11.50697489
27EPHA31.49698159
28EEF2K1.49509472
29PAK31.47278934
30MINK11.42921576
31LATS21.41897884
32CDK121.40685973
33TYRO31.40149730
34FER1.39459881
35PTK61.39376112
36STK38L1.39081990
37WNK11.38485868
38PRKCH1.32573021
39ERBB31.30159039
40MARK11.25695419
41WNK31.25319792
42SIK21.24764732
43ALK1.22801766
44PNCK1.22171139
45CAMK1D1.19367913
46AKT31.17101325
47NTRK21.14531643
48LATS11.14470847
49PTK21.14458309
50BMX1.13874990
51SIK11.13306337
52PDGFRB1.12563426
53YES11.11892507
54STK381.11775891
55NLK1.10183867
56NEK91.07150747
57FGFR21.06016845
58ICK1.00411283
59KSR10.99614572
60TRIM280.99344630
61PHKG20.97901971
62PHKG10.97901971
63CDC42BPA0.97173225
64CDK50.96583285
65PLK20.96313405
66CSNK1A1L0.93872121
67PTK2B0.91149786
68DAPK20.89824489
69EPHB20.87566962
70MTOR0.86424431
71PAK20.85876212
72FGFR10.84184473
73TGFBR20.83530299
74STK110.83289112
75FLT30.83154230
76ROCK20.82756720
77MAP2K40.82712638
78WNK40.81984466
79CSNK1G10.79833058
80ROCK10.77683226
81MAPK130.76702871
82LIMK10.76593548
83EPHB10.75322184
84EPHA20.74952637
85MARK20.72643751
86STK390.70313391
87SGK30.69629937
88TIE10.69212672
89UHMK10.69018664
90DYRK1B0.68366973
91RPS6KA20.66693648
92STK30.64793405
93MST1R0.64577191
94MAP3K100.63331333
95SGK20.62706133
96MAP3K70.62140501
97RIPK40.61603682
98FGFR30.61382669
99ERBB40.60845213
100MAP4K20.60407876
101PRKD10.59830361
102MAP2K10.58832732
103CAMKK20.57977483
104ERBB20.57807712
105PRKAA10.57726229
106FYN0.57256354
107SGK10.55017413
108CDK140.53294206
109BRD40.52842202
110MAPK100.52053323
111DYRK20.51939659
112PAK40.51866083
113CDK150.51499444
114FRK0.50942314
115DYRK1A0.50721460
116SRC0.50145344
117CSNK1G30.49687968
118MAP3K10.48119709
119PDPK10.47222004
120MYLK0.46347752
121MELK0.45997517
122CDK180.45540884
123CAMK2A0.45495100
124RPS6KA30.45491562
125TAOK10.45482917
126PRKD20.44191322
127CSNK1G20.43180414
128CSNK1D0.42963282
129PRKCE0.42716091
130JAK10.42283647
131HIPK20.41898115
132PDK10.41836239
133SGK2230.41680411
134SGK4940.41680411
135FGR0.41462195
136PIK3CA0.41204086
137LRRK20.41139712

Predicted pathways (KEGG)

RankGene SetZ-score
1Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.06532850
2Long-term potentiation_Homo sapiens_hsa047201.82784696
3Glycosaminoglycan degradation_Homo sapiens_hsa005311.64749617
4Circadian entrainment_Homo sapiens_hsa047131.64530983
5Gastric acid secretion_Homo sapiens_hsa049711.58937181
6Salivary secretion_Homo sapiens_hsa049701.56799619
7Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56034229
8Dilated cardiomyopathy_Homo sapiens_hsa054141.54940439
9Steroid biosynthesis_Homo sapiens_hsa001001.54838833
10Insulin secretion_Homo sapiens_hsa049111.54690810
11Lysine degradation_Homo sapiens_hsa003101.54531336
12Nicotine addiction_Homo sapiens_hsa050331.54110166
13Synaptic vesicle cycle_Homo sapiens_hsa047211.50104715
14Aldosterone synthesis and secretion_Homo sapiens_hsa049251.48511032
15Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.48304881
16Glioma_Homo sapiens_hsa052141.46332646
17Amphetamine addiction_Homo sapiens_hsa050311.46289625
18Renin secretion_Homo sapiens_hsa049241.43565216
19Glutamatergic synapse_Homo sapiens_hsa047241.43065663
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.42940005
21GABAergic synapse_Homo sapiens_hsa047271.42919093
22Dopaminergic synapse_Homo sapiens_hsa047281.41796777
23ECM-receptor interaction_Homo sapiens_hsa045121.41102407
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.40822728
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.40637829
26Type II diabetes mellitus_Homo sapiens_hsa049301.40029742
27Estrogen signaling pathway_Homo sapiens_hsa049151.37317593
28Focal adhesion_Homo sapiens_hsa045101.36805571
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.36336195
30Cholinergic synapse_Homo sapiens_hsa047251.36080927
31Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.35160118
32Dorso-ventral axis formation_Homo sapiens_hsa043201.33472264
33Olfactory transduction_Homo sapiens_hsa047401.31272381
34Morphine addiction_Homo sapiens_hsa050321.31032982
35Gap junction_Homo sapiens_hsa045401.30426378
36Oxytocin signaling pathway_Homo sapiens_hsa049211.29546462
37Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.28435467
38GnRH signaling pathway_Homo sapiens_hsa049121.27960940
39N-Glycan biosynthesis_Homo sapiens_hsa005101.24582399
40Axon guidance_Homo sapiens_hsa043601.23099088
41Long-term depression_Homo sapiens_hsa047301.23017394
42Cocaine addiction_Homo sapiens_hsa050301.19275402
43Proteoglycans in cancer_Homo sapiens_hsa052051.18555864
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.18284594
45Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.17722503
46mTOR signaling pathway_Homo sapiens_hsa041501.14816913
47Melanogenesis_Homo sapiens_hsa049161.14350032
48Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.14116803
49Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.10904523
50TGF-beta signaling pathway_Homo sapiens_hsa043501.10784714
51Thyroid hormone signaling pathway_Homo sapiens_hsa049191.10726801
52cAMP signaling pathway_Homo sapiens_hsa040241.07781209
53Adherens junction_Homo sapiens_hsa045201.03851861
54Phosphatidylinositol signaling system_Homo sapiens_hsa040701.02966312
55ErbB signaling pathway_Homo sapiens_hsa040121.02396011
56Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.02202288
57Neurotrophin signaling pathway_Homo sapiens_hsa047221.01959815
58Endometrial cancer_Homo sapiens_hsa052131.01252587
59Phospholipase D signaling pathway_Homo sapiens_hsa040721.00069840
60PI3K-Akt signaling pathway_Homo sapiens_hsa041510.99977390
61Calcium signaling pathway_Homo sapiens_hsa040200.99678838
62Renal cell carcinoma_Homo sapiens_hsa052110.99206711
63Amoebiasis_Homo sapiens_hsa051460.98950558
64Maturity onset diabetes of the young_Homo sapiens_hsa049500.95309044
65Taste transduction_Homo sapiens_hsa047420.94419496
66Vitamin B6 metabolism_Homo sapiens_hsa007500.94080328
67Thyroid hormone synthesis_Homo sapiens_hsa049180.94053562
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.92328356
69Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.92015949
70Chronic myeloid leukemia_Homo sapiens_hsa052200.91492015
71VEGF signaling pathway_Homo sapiens_hsa043700.90973693
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90186545
73Thyroid cancer_Homo sapiens_hsa052160.90066837
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.89831393
75Rap1 signaling pathway_Homo sapiens_hsa040150.88946215
76Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.88877955
77Carbohydrate digestion and absorption_Homo sapiens_hsa049730.87579669
78Complement and coagulation cascades_Homo sapiens_hsa046100.86175742
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.85927712
80Hippo signaling pathway_Homo sapiens_hsa043900.85257666
81Sphingolipid metabolism_Homo sapiens_hsa006000.84802702
82Serotonergic synapse_Homo sapiens_hsa047260.84722052
83Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84419898
84Protein digestion and absorption_Homo sapiens_hsa049740.84136125
85Non-small cell lung cancer_Homo sapiens_hsa052230.83441079
86ABC transporters_Homo sapiens_hsa020100.82935009
87Pancreatic secretion_Homo sapiens_hsa049720.82748415
88Central carbon metabolism in cancer_Homo sapiens_hsa052300.81365632
89Propanoate metabolism_Homo sapiens_hsa006400.81254660
90Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.81130784
91Fatty acid metabolism_Homo sapiens_hsa012120.80206848
92Wnt signaling pathway_Homo sapiens_hsa043100.79980528
93Hedgehog signaling pathway_Homo sapiens_hsa043400.78865079
94Tight junction_Homo sapiens_hsa045300.78595092
95Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.78308344
96Choline metabolism in cancer_Homo sapiens_hsa052310.76826601
97Platelet activation_Homo sapiens_hsa046110.76504517
98Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.75244684
99Colorectal cancer_Homo sapiens_hsa052100.74774612
100MAPK signaling pathway_Homo sapiens_hsa040100.74594817
101AMPK signaling pathway_Homo sapiens_hsa041520.74198188
102Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73425989
103Insulin signaling pathway_Homo sapiens_hsa049100.72591357
104Endocytosis_Homo sapiens_hsa041440.72453495
105Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71994304
106Glucagon signaling pathway_Homo sapiens_hsa049220.71675823
107Longevity regulating pathway - mammal_Homo sapiens_hsa042110.71599991
108Pancreatic cancer_Homo sapiens_hsa052120.70756368
109Small cell lung cancer_Homo sapiens_hsa052220.70737887
110Non-homologous end-joining_Homo sapiens_hsa034500.70620462
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68534156
112Pathways in cancer_Homo sapiens_hsa052000.67660620
113MicroRNAs in cancer_Homo sapiens_hsa052060.67524757
114Selenocompound metabolism_Homo sapiens_hsa004500.67220960
115Basal cell carcinoma_Homo sapiens_hsa052170.66608492
116Insulin resistance_Homo sapiens_hsa049310.66222290
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.66155045
118Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65697947
119Oocyte meiosis_Homo sapiens_hsa041140.65093721
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64462744
121Bladder cancer_Homo sapiens_hsa052190.63944632
122Melanoma_Homo sapiens_hsa052180.63781068
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.63485542
124Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.61502246
125Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60880399
126Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60118656
127Inositol phosphate metabolism_Homo sapiens_hsa005620.59520708
128Prostate cancer_Homo sapiens_hsa052150.59296259
129Fatty acid biosynthesis_Homo sapiens_hsa000610.59289668
130Circadian rhythm_Homo sapiens_hsa047100.58598057
131Vibrio cholerae infection_Homo sapiens_hsa051100.58111437
132Butanoate metabolism_Homo sapiens_hsa006500.56979010
133Ras signaling pathway_Homo sapiens_hsa040140.55775861
134Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54007440
135Other glycan degradation_Homo sapiens_hsa005110.52006772
136Galactose metabolism_Homo sapiens_hsa000520.51375253
137Notch signaling pathway_Homo sapiens_hsa043300.50984963

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