GLMP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1daunorubicin metabolic process (GO:0044597)5.66607203
2polyketide metabolic process (GO:0030638)5.66607203
3doxorubicin metabolic process (GO:0044598)5.66607203
4oligosaccharide catabolic process (GO:0009313)4.82602113
5melanin biosynthetic process (GO:0042438)4.68484079
6aminoglycoside antibiotic metabolic process (GO:0030647)4.43530541
7adhesion of symbiont to host (GO:0044406)4.34858683
8regulation of mononuclear cell migration (GO:0071675)4.32048133
9sphingolipid catabolic process (GO:0030149)4.26710576
10membrane lipid catabolic process (GO:0046466)4.22043664
11secondary metabolite biosynthetic process (GO:0044550)4.05849506
12melanin metabolic process (GO:0006582)3.97607237
13plasma lipoprotein particle clearance (GO:0034381)3.73891455
14regulation of cholesterol esterification (GO:0010872)3.64840064
15N-acetylneuraminate metabolic process (GO:0006054)3.45255716
16regulation of cytokine secretion involved in immune response (GO:0002739)3.42382124
17cellular response to thyroid hormone stimulus (GO:0097067)3.38011397
18positive regulation by symbiont of host defense response (GO:0052509)3.30380318
19modulation by symbiont of host defense response (GO:0052031)3.30380318
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.30380318
21modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.30380318
22positive regulation by organism of defense response of other organism involved in symbiotic interact3.30380318
23modulation by symbiont of host immune response (GO:0052553)3.30380318
24fat-soluble vitamin biosynthetic process (GO:0042362)3.30235706
25glycoside metabolic process (GO:0016137)3.29437811
26regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.23803598
27protein carboxylation (GO:0018214)3.21641934
28peptidyl-glutamic acid carboxylation (GO:0017187)3.21641934
29lytic vacuole organization (GO:0080171)3.18935427
30lysosome organization (GO:0007040)3.18935427
31keratan sulfate catabolic process (GO:0042340)3.15250328
32GDP-mannose metabolic process (GO:0019673)3.14129156
33positive regulation of triglyceride lipase activity (GO:0061365)3.11281117
34positive regulation of lipoprotein lipase activity (GO:0051006)3.11281117
35negative regulation of nitric oxide biosynthetic process (GO:0045019)3.10388051
36regulation of interferon-beta biosynthetic process (GO:0045357)3.09539861
37low-density lipoprotein particle clearance (GO:0034383)3.09181194
38pinocytosis (GO:0006907)3.08715049
39cytidine metabolic process (GO:0046087)3.08544947
40cytidine catabolic process (GO:0006216)3.08544947
41cytidine deamination (GO:0009972)3.08544947
42barbed-end actin filament capping (GO:0051016)3.05958683
43erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.02504303
44L-phenylalanine metabolic process (GO:0006558)3.02504303
45regulation of apoptotic process involved in morphogenesis (GO:1902337)3.01834637
46neutrophil activation involved in immune response (GO:0002283)2.99664031
47positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.98510501
48cholesterol efflux (GO:0033344)2.97514639
49apoptotic cell clearance (GO:0043277)2.96546237
50regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.96032286
51regulation of macrophage chemotaxis (GO:0010758)2.92686974
52phospholipid efflux (GO:0033700)2.92336979
53fibrinolysis (GO:0042730)2.91478593
54regulation of membrane protein ectodomain proteolysis (GO:0051043)2.91242214
55positive regulation of chemokine biosynthetic process (GO:0045080)2.90536231
56tyrosine metabolic process (GO:0006570)2.88617525
57amino sugar catabolic process (GO:0046348)2.88356065
58regulation of apoptotic cell clearance (GO:2000425)2.88215492
59mannose metabolic process (GO:0006013)2.87771183
60endosome to pigment granule transport (GO:0043485)2.87564182
61endosome to melanosome transport (GO:0035646)2.87564182
62negative regulation of fibrinolysis (GO:0051918)2.85686879
63response to peptidoglycan (GO:0032494)2.84528323
64immunoglobulin mediated immune response (GO:0016064)2.83081691
65hyaluronan catabolic process (GO:0030214)2.83058618
66complement activation, alternative pathway (GO:0006957)2.82722572
67fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.77320472
68monocyte chemotaxis (GO:0002548)2.76555321
69regulation of fibrinolysis (GO:0051917)2.75024311
70negative regulation of interleukin-12 production (GO:0032695)2.74772358
71phagocytosis, recognition (GO:0006910)2.74058926
72regulation of superoxide anion generation (GO:0032928)2.73787855
73regulation of cholesterol storage (GO:0010885)2.73746132
74amyloid precursor protein catabolic process (GO:0042987)2.72916400
75cyclooxygenase pathway (GO:0019371)2.71295844
76muscle organ morphogenesis (GO:0048644)2.69497471
77negative regulation of sterol transport (GO:0032372)2.69376729
78negative regulation of cholesterol transport (GO:0032375)2.69376729
79eosinophil chemotaxis (GO:0048245)2.64991719
80skin morphogenesis (GO:0043589)2.63586737
81regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.63126036
82antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.62907445
83regulation of mammary gland epithelial cell proliferation (GO:0033599)2.60645218
84positive regulation of extracellular matrix organization (GO:1903055)2.58686898
85erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.58027388
86L-phenylalanine catabolic process (GO:0006559)2.58027388
87hormone catabolic process (GO:0042447)2.56172378
88glycosylceramide metabolic process (GO:0006677)2.55360721
89plasma lipoprotein particle assembly (GO:0034377)2.55034681
90negative regulation of coagulation (GO:0050819)2.54766984
91regulation of vitamin D biosynthetic process (GO:0060556)2.54655604
92decidualization (GO:0046697)2.54590151
93endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.54220983
94glycosphingolipid metabolic process (GO:0006687)2.53476660
95primary alcohol catabolic process (GO:0034310)2.53125862
96sphingosine metabolic process (GO:0006670)2.51634614
97intestinal epithelial cell development (GO:0060576)2.50034800
98macrophage activation involved in immune response (GO:0002281)2.49584068
99glycosphingolipid catabolic process (GO:0046479)2.49365488
100interferon-gamma secretion (GO:0072643)2.49284724
101triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.47686063
102vitamin D metabolic process (GO:0042359)2.47550203
103very-low-density lipoprotein particle assembly (GO:0034379)2.46497109
104cofactor transport (GO:0051181)2.45769214
105intracellular pH reduction (GO:0051452)2.45761633
106regulation of chemokine biosynthetic process (GO:0045073)2.45265299
107cellular modified amino acid catabolic process (GO:0042219)2.44330644
108membrane protein intracellular domain proteolysis (GO:0031293)2.43922444
109modified amino acid transport (GO:0072337)2.43429266
110antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.42648273
111antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.42648273
112glial cell migration (GO:0008347)2.42637907
113cellular response to arsenic-containing substance (GO:0071243)2.42382494
114positive regulation of interferon-alpha production (GO:0032727)2.41758230
115protein-lipid complex assembly (GO:0065005)2.41220148
116interferon-gamma production (GO:0032609)2.40939035
117regulation of monocyte chemotaxis (GO:0090025)2.39847685
118sulfur amino acid catabolic process (GO:0000098)2.39670573
119protein localization to endosome (GO:0036010)2.39462296
120peptide catabolic process (GO:0043171)2.39450821
121positive regulation of monocyte chemotaxis (GO:0090026)2.39381355
122nucleotide-sugar biosynthetic process (GO:0009226)2.38366850
123high-density lipoprotein particle remodeling (GO:0034375)2.38245218
124lipopolysaccharide-mediated signaling pathway (GO:0031663)2.38128698
125positive regulation of lymphocyte apoptotic process (GO:0070230)2.35990763
126pH reduction (GO:0045851)2.35021159
127low-density lipoprotein particle remodeling (GO:0034374)2.34268304
128positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.33957573
129glycolipid catabolic process (GO:0019377)2.33848665
130L-alpha-amino acid transmembrane transport (GO:1902475)2.33282364
131regulation of response to osmotic stress (GO:0047484)2.32645543
132response to pH (GO:0009268)2.32627898
133eosinophil migration (GO:0072677)2.32579275
134hydrogen peroxide biosynthetic process (GO:0050665)2.32511694
135nucleoside transport (GO:0015858)2.30306329
136regulation of interferon-alpha production (GO:0032647)2.30171150
137branching involved in mammary gland duct morphogenesis (GO:0060444)2.29454313
138nucleoside transmembrane transport (GO:1901642)2.28360217
139antigen processing and presentation of endogenous antigen (GO:0019883)2.26767173
140positive regulation of tissue remodeling (GO:0034105)2.26193466
141folic acid transport (GO:0015884)2.25859699
142phagocytosis, engulfment (GO:0006911)2.24704124
143cellular extravasation (GO:0045123)2.24368553
144regulation of chemokine secretion (GO:0090196)2.21804592
145diol metabolic process (GO:0034311)2.21551267
146signal peptide processing (GO:0006465)2.20205681
147ceramide catabolic process (GO:0046514)2.19492385
148pyrimidine ribonucleoside catabolic process (GO:0046133)2.19289721
149respiratory burst (GO:0045730)2.18514796
150Arp2/3 complex-mediated actin nucleation (GO:0034314)2.15722103
151adhesion of symbiont to host cell (GO:0044650)2.15692224
152virion attachment to host cell (GO:0019062)2.15692224
153branching involved in labyrinthine layer morphogenesis (GO:0060670)2.15641016
154regulation of antigen processing and presentation (GO:0002577)2.15106280
155negative regulation of phagocytosis (GO:0050765)2.14990960
156wound healing, spreading of epidermal cells (GO:0035313)2.14932431
157L-ascorbic acid metabolic process (GO:0019852)2.14914802
158pentose-phosphate shunt (GO:0006098)2.14642854
159B cell mediated immunity (GO:0019724)2.14504447
160negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.14188629
161response to thyroid hormone (GO:0097066)2.14087208
162regulation of translation in response to stress (GO:0043555)2.13198868
163reactive oxygen species biosynthetic process (GO:1903409)2.12057304
164positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.11034319
165regulation of integrin-mediated signaling pathway (GO:2001044)2.09142587
166valine metabolic process (GO:0006573)2.06514316
167establishment of endothelial barrier (GO:0061028)2.06159951
168negative regulation of epidermis development (GO:0045683)2.05654367
169maintenance of protein location in nucleus (GO:0051457)2.05458958
170positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.05234422
171pentose metabolic process (GO:0019321)2.04156834
172basement membrane organization (GO:0071711)2.02728476
173response to laminar fluid shear stress (GO:0034616)2.02542105
174positive regulation of antigen processing and presentation (GO:0002579)2.02422157
175negative regulation of telomerase activity (GO:0051974)2.02107700
176positive regulation of chemokine secretion (GO:0090197)2.02007382
177intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)2.01725274
178myeloid cell homeostasis (GO:0002262)2.01167626

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.03554233
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.40903647
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.12730754
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.07731571
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.07728046
6KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.04244110
7KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.04244110
8KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.04244110
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.36884888
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.35107982
11NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.08991514
12POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.92225283
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.87822792
14IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.86584144
15STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.85690039
16FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.83770388
17RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.81787836
18RARG_19884340_ChIP-ChIP_MEFs_Mouse1.81422029
19IRF8_27001747_Chip-Seq_BMDM_Mouse1.77279478
20SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.76048233
21PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.66275474
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.58610197
23VDR_21846776_ChIP-Seq_THP-1_Human1.58150093
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56775449
25TRIM28_21343339_ChIP-Seq_HEK293_Human1.55977699
26STAT3_1855785_ChIP-Seq_MESCs_Mouse1.54853371
27MYB_21317192_ChIP-Seq_ERMYB_Mouse1.54668523
28NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.54415132
29SRY_22984422_ChIP-ChIP_TESTIS_Rat1.53784405
30MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.53752650
31SPI1_23547873_ChIP-Seq_NB4_Human1.52157912
32ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.51912688
33EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.50102580
34TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.46360283
35TCF3_18692474_ChIP-Seq_MEFs_Mouse1.46094987
36PPARA_22158963_ChIP-Seq_LIVER_Mouse1.42507546
37TFEB_21752829_ChIP-Seq_HELA_Human1.42316113
38KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.42064539
39SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.40728453
40KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.38893338
41VDR_24763502_ChIP-Seq_THP-1_Human1.36809433
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34170789
43EGR1_23403033_ChIP-Seq_LIVER_Mouse1.34040014
44TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33061663
45RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.32688948
46SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.31647466
47ELF1_20517297_ChIP-Seq_JURKAT_Human1.30980567
48Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.30484700
49RXR_22158963_ChIP-Seq_LIVER_Mouse1.29593075
50ELK3_25401928_ChIP-Seq_HUVEC_Human1.29404749
51IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.28260138
52HIF1A_21447827_ChIP-Seq_MCF-7_Human1.28100764
53ZNF263_19887448_ChIP-Seq_K562_Human1.27073268
54TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.26775620
55BCOR_27268052_Chip-Seq_Bcells_Human1.26755130
56CREB1_15753290_ChIP-ChIP_HEK293T_Human1.26113843
57BRD4_27068464_Chip-Seq_AML-cells_Mouse1.25821624
58CTCF_18555785_ChIP-Seq_MESCs_Mouse1.25799281
59SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.25148586
60BCL6_27268052_Chip-Seq_Bcells_Human1.25066047
61JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.24661078
62NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.24527866
63UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.23232994
64GABP_17652178_ChIP-ChIP_JURKAT_Human1.22629198
65NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.20309072
66ESR2_21235772_ChIP-Seq_MCF-7_Human1.18326837
67HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.17665319
68NANOG_18555785_ChIP-Seq_MESCs_Mouse1.17280921
69LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.16841795
70SMC3_22415368_ChIP-Seq_MEFs_Mouse1.16777486
71PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.16524613
72PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15911717
73SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.15528000
74CDX2_20551321_ChIP-Seq_CACO-2_Human1.12754765
75E2F1_18555785_ChIP-Seq_MESCs_Mouse1.12120533
76TET1_21451524_ChIP-Seq_MESCs_Mouse1.12108350
77CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.11921446
78CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.11748805
79MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.11237898
80SA1_27219007_Chip-Seq_ERYTHROID_Human1.10728796
81SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10621207
82ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.10514265
83STAT4_19710469_ChIP-ChIP_TH1__Mouse1.10335193
84MYC_18358816_ChIP-ChIP_MESCs_Mouse1.09776808
85ESR1_21235772_ChIP-Seq_MCF-7_Human1.09256838
86RACK7_27058665_Chip-Seq_MCF-7_Human1.08914440
87P63_26484246_Chip-Seq_KERATINOCYTES_Human1.08164203
88SA1_27219007_Chip-Seq_Bcells_Human1.08075265
89EST1_17652178_ChIP-ChIP_JURKAT_Human1.07655517
90CTCF_20526341_ChIP-Seq_ESCs_Human1.07563567
91CTCF_26484167_Chip-Seq_Bcells_Mouse1.07179271
92ELK1_22589737_ChIP-Seq_MCF10A_Human1.06752133
93GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.05142345
94THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04916199
95RUNX1_22412390_ChIP-Seq_EML_Mouse1.04055936
96ELF1_17652178_ChIP-ChIP_JURKAT_Human1.03420880
97SOX2_18692474_ChIP-Seq_MEFs_Mouse1.02799174
98NANOG_18692474_ChIP-Seq_MEFs_Mouse1.02506917
99OCT4_18692474_ChIP-Seq_MEFs_Mouse1.01230401
100SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00718471
101CTCF_27219007_Chip-Seq_ERYTHROID_Human1.00127511
102P68_20966046_ChIP-Seq_HELA_Human0.99868144
103ATF3_27146783_Chip-Seq_COLON_Human0.99535125
104LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97977366
105CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97681267
106DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.97532224
107RARB_24833708_ChIP-Seq_LIVER_Mouse0.97382487
108RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97207281
109ETS1_20019798_ChIP-Seq_JURKAT_Human0.97052969
110E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.96858673
111CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.96713943
112PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.96544427
113NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.96343170
114SPI1_23127762_ChIP-Seq_K562_Human0.96290848
115SMC1_22415368_ChIP-Seq_MEFs_Mouse0.96222035
116CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.96080665
117CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.96079760
118LXR_22292898_ChIP-Seq_THP-1_Human0.95505216
119MAF_26560356_Chip-Seq_TH1_Human0.95497858
120SOX2_20726797_ChIP-Seq_SW620_Human0.95389689
121PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95347097
122SRF_21415370_ChIP-Seq_HL-1_Mouse0.94233110
123TP53_22127205_ChIP-Seq_IMR90_Human0.93990269
124SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.93798785
125MYC_18555785_ChIP-Seq_MESCs_Mouse0.93537848
126TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.93329501
127CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92916115
128SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92192701
129CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.92012007
130CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.91566098
131LXR_22158963_ChIP-Seq_LIVER_Mouse0.91521330
132CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90777920
133PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.89423142
134ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.89362479
135CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.88385403
136GATA4_25053715_ChIP-Seq_YYC3_Human0.88209908
137MYB_26560356_Chip-Seq_TH2_Human0.87548598
138HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.87072571
139TCF3_18692474_ChIP-Seq_MESCs_Mouse0.86916514

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system3.92349542
2MP0005058_abnormal_lysosome_morphology3.75343952
3MP0005171_absent_coat_pigmentation3.25004907
4MP0003136_yellow_coat_color3.03263974
5MP0005408_hypopigmentation2.90634558
6MP0006082_CNS_inflammation2.83786800
7MP0009840_abnormal_foam_cell2.71734181
8MP0002254_reproductive_system_inflammat2.55318009
9MP0003011_delayed_dark_adaptation2.45813573
10MP0005365_abnormal_bile_salt2.30151019
11MP0008438_abnormal_cutaneous_collagen2.25378632
12MP0003172_abnormal_lysosome_physiology2.22265490
13MP0003436_decreased_susceptibility_to2.18219864
14MP0005257_abnormal_intraocular_pressure2.16517173
15MP0001835_abnormal_antigen_presentation2.09668173
16MP0000371_diluted_coat_color1.97594946
17MP0004264_abnormal_extraembryonic_tissu1.86725123
18MP0003705_abnormal_hypodermis_morpholog1.86398994
19MP0005360_urolithiasis1.85417460
20MP0009785_altered_susceptibility_to1.78011761
21MP0003186_abnormal_redox_activity1.71974872
22MP0002419_abnormal_innate_immunity1.69857856
23MP0000015_abnormal_ear_pigmentation1.68958699
24MP0000343_altered_response_to1.64967097
25MP0002148_abnormal_hypersensitivity_rea1.64959592
26MP0005000_abnormal_immune_tolerance1.63699325
27MP0005025_abnormal_response_to1.63250449
28MP0000858_altered_metastatic_potential1.63203553
29MP0003566_abnormal_cell_adhesion1.59514918
30MP0003300_gastrointestinal_ulcer1.59417930
31MP0003075_altered_response_to1.55910901
32MP0005387_immune_system_phenotype1.54413099
33MP0001790_abnormal_immune_system1.54413099
34MP0009333_abnormal_splenocyte_physiolog1.53405441
35MP0003183_abnormal_peptide_metabolism1.52862589
36MP0005023_abnormal_wound_healing1.51090956
37MP0005451_abnormal_body_composition1.48147442
38MP0003724_increased_susceptibility_to1.43021498
39MP0005075_abnormal_melanosome_morpholog1.42674579
40MP0001533_abnormal_skeleton_physiology1.39175627
41MP0003448_altered_tumor_morphology1.35339511
42MP0002452_abnormal_antigen_presenting1.34744374
43MP0005671_abnormal_response_to1.34661471
44MP0002090_abnormal_vision1.34558173
45MP0010352_gastrointestinal_tract_polyps1.33289762
46MP0001958_emphysema1.33057284
47MP0003191_abnormal_cellular_cholesterol1.33034006
48MP0005174_abnormal_tail_pigmentation1.28499309
49MP0002837_dystrophic_cardiac_calcinosis1.28292691
50MP0002405_respiratory_system_inflammati1.26003784
51MP0009643_abnormal_urine_homeostasis1.25353523
52MP0008875_abnormal_xenobiotic_pharmacok1.25073181
53MP0004947_skin_inflammation1.24405193
54MP0004019_abnormal_vitamin_homeostasis1.23258167
55MP0002132_abnormal_respiratory_system1.22855859
56MP0001324_abnormal_eye_pigmentation1.21953463
57MP0000685_abnormal_immune_system1.21890373
58MP0001853_heart_inflammation1.21213485
59MP0002723_abnormal_immune_serum1.20989158
60MP0005085_abnormal_gallbladder_physiolo1.20262851
61MP0001800_abnormal_humoral_immune1.20197442
62MP0000490_abnormal_crypts_of1.20125259
63MP0004510_myositis1.18547171
64MP0003279_aneurysm1.18503990
65MP0001542_abnormal_bone_strength1.18383438
66MP0002075_abnormal_coat/hair_pigmentati1.17339647
67MP0001845_abnormal_inflammatory_respons1.15583589
68MP0001819_abnormal_immune_cell1.13685642
69MP0008469_abnormal_protein_level1.12529991
70MP0002420_abnormal_adaptive_immunity1.12298049
71MP0002138_abnormal_hepatobiliary_system1.12219579
72MP0010155_abnormal_intestine_physiology1.11651570
73MP0003303_peritoneal_inflammation1.10583959
74MP0005390_skeleton_phenotype1.10141444
75MP0005310_abnormal_salivary_gland1.10028646
76MP0009764_decreased_sensitivity_to1.07986606
77MP0003453_abnormal_keratinocyte_physiol1.07428577
78MP0002998_abnormal_bone_remodeling1.07386645
79MP0005197_abnormal_uvea_morphology1.06251418
80MP0001186_pigmentation_phenotype1.06021797
81MP0003806_abnormal_nucleotide_metabolis1.04554021
82MP0003195_calcinosis1.03502804
83MP0004782_abnormal_surfactant_physiolog1.02884763
84MP0000372_irregular_coat_pigmentation1.00536723
85MP0008260_abnormal_autophagy1.00464256
86MP0002136_abnormal_kidney_physiology1.00228578
87MP0004858_abnormal_nervous_system0.99032443
88MP0005167_abnormal_blood-brain_barrier0.97519098
89MP0004272_abnormal_basement_membrane0.96390330
90MP0000678_abnormal_parathyroid_gland0.95568561
91MP0005508_abnormal_skeleton_morphology0.95035910
92MP0002933_joint_inflammation0.93778121
93MP0005164_abnormal_response_to0.93355115
94MP0004957_abnormal_blastocyst_morpholog0.93212439
95MP0005595_abnormal_vascular_smooth0.92739665
96MP0005332_abnormal_amino_acid0.91957781
97MP0005464_abnormal_platelet_physiology0.91603023
98MP0000689_abnormal_spleen_morphology0.91522330
99MP0002277_abnormal_respiratory_mucosa0.90792328
100MP0002295_abnormal_pulmonary_circulatio0.89603394
101MP0000920_abnormal_myelination0.89423477
102MP0010329_abnormal_lipoprotein_level0.89336838
103MP0001756_abnormal_urination0.89115761
104MP0002938_white_spotting0.87716700
105MP0005319_abnormal_enzyme/_coenzyme0.87176456
106MP0000716_abnormal_immune_system0.85347479
107MP0002722_abnormal_immune_system0.85243666
108MP0008004_abnormal_stomach_pH0.85130123
109MP0003795_abnormal_bone_structure0.83890108
110MP0000249_abnormal_blood_vessel0.83064375
111MP0006054_spinal_hemorrhage0.82949729
112MP0004381_abnormal_hair_follicle0.82690325
113MP0000604_amyloidosis0.82144958
114MP0000609_abnormal_liver_physiology0.81825476
115MP0002098_abnormal_vibrissa_morphology0.81584337
116MP0001243_abnormal_dermal_layer0.81457018
117MP0003329_amyloid_beta_deposits0.80697863
118MP0002396_abnormal_hematopoietic_system0.80240386
119MP0009384_cardiac_valve_regurgitation0.80070106
120MP0002095_abnormal_skin_pigmentation0.80034217
121MP0002429_abnormal_blood_cell0.79653746
122MP0001849_ear_inflammation0.76942009
123MP0005165_increased_susceptibility_to0.74474988
124MP0002060_abnormal_skin_morphology0.74463514
125MP0003828_pulmonary_edema0.73611081
126MP0002877_abnormal_melanocyte_morpholog0.73526357
127MP0004883_abnormal_blood_vessel0.72958924
128MP0005503_abnormal_tendon_morphology0.72858355
129MP0010030_abnormal_orbit_morphology0.72826274
130MP0010386_abnormal_urinary_bladder0.72772202
131MP0000767_abnormal_smooth_muscle0.70908061
132MP0003634_abnormal_glial_cell0.70245685
133MP0000598_abnormal_liver_morphology0.69828958
134MP0000465_gastrointestinal_hemorrhage0.69146475
135MP0001764_abnormal_homeostasis0.69100870
136MP0003690_abnormal_glial_cell0.68498004

Predicted human phenotypes

RankGene SetZ-score
1Vacuolated lymphocytes (HP:0001922)5.78795242
2Abnormality of glycolipid metabolism (HP:0010969)4.88976637
3Abnormality of liposaccharide metabolism (HP:0010968)4.88976637
4Abnormality of glycosphingolipid metabolism (HP:0004343)4.88976637
5Increased cerebral lipofuscin (HP:0011813)4.21120504
6Dysostosis multiplex (HP:0000943)4.04667683
7Increased neuronal autofluorescent lipopigment (HP:0002074)4.01395748
8Nuclear cataract (HP:0100018)3.94823027
9Complement deficiency (HP:0004431)3.44404223
10Abnormality of macrophages (HP:0004311)3.36573125
11Urinary glycosaminoglycan excretion (HP:0003541)3.36390452
12Mucopolysacchariduria (HP:0008155)3.36390452
13Recurrent abscess formation (HP:0002722)3.31228150
14Multiple enchondromatosis (HP:0005701)3.13006094
15Cervical subluxation (HP:0003308)3.12664157
16Premature rupture of membranes (HP:0001788)3.12515129
17Abnormality of mucopolysaccharide metabolism (HP:0011020)3.09970985
18Abnormality of polysaccharide metabolism (HP:0011012)3.09970985
19Abnormality of glycosaminoglycan metabolism (HP:0004371)3.09970985
20Bilateral microphthalmos (HP:0007633)3.05860283
21Systemic lupus erythematosus (HP:0002725)3.04293209
22Abnormality of complement system (HP:0005339)2.95967124
23Eczematoid dermatitis (HP:0000976)2.87845350
24Recurrent bacterial skin infections (HP:0005406)2.86398465
25Elevated erythrocyte sedimentation rate (HP:0003565)2.84117116
26Disinhibition (HP:0000734)2.82005961
27White forelock (HP:0002211)2.77230847
28Patchy hypopigmentation of hair (HP:0011365)2.73641618
29J-shaped sella turcica (HP:0002680)2.64707735
30Pustule (HP:0200039)2.63614215
31Vertebral compression fractures (HP:0002953)2.63127536
32Axonal loss (HP:0003447)2.62939446
33Cheilitis (HP:0100825)2.62168837
34Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.61301578
35Mutism (HP:0002300)2.61262141
36Poor head control (HP:0002421)2.57106475
37Deep venous thrombosis (HP:0002625)2.56760380
38Trismus (HP:0000211)2.55995246
39Reduced antithrombin III activity (HP:0001976)2.50056901
40Retinal atrophy (HP:0001105)2.48825827
41Neurofibrillary tangles (HP:0002185)2.46511960
42Petechiae (HP:0000967)2.44182848
43Paraparesis (HP:0002385)2.43114818
44Interstitial pulmonary disease (HP:0006530)2.42035202
45Fused cervical vertebrae (HP:0002949)2.41191856
46Mesangial abnormality (HP:0001966)2.39628171
47Ocular albinism (HP:0001107)2.38758212
48Abnormality of monocarboxylic acid metabolism (HP:0010996)2.31680541
49Abnormal hemoglobin (HP:0011902)2.29307285
50Spastic paraparesis (HP:0002313)2.28277252
51Purpura (HP:0000979)2.25853949
52Aplasia/Hypoplasia of the fovea (HP:0008060)2.25694290
53Hypoplasia of the fovea (HP:0007750)2.25694290
54Ovoid vertebral bodies (HP:0003300)2.20682017
55Peritonitis (HP:0002586)2.19920280
56Abnormality of aromatic amino acid family metabolism (HP:0004338)2.18846737
57Cardiomegaly (HP:0001640)2.18078889
58Myositis (HP:0100614)2.17982005
59Amyloidosis (HP:0011034)2.16267578
60Gingivitis (HP:0000230)2.14941956
61Hepatosplenomegaly (HP:0001433)2.13789043
62Type I transferrin isoform profile (HP:0003642)2.13758460
63Aplasia/Hypoplasia of the macula (HP:0008059)2.13644431
64Nephritis (HP:0000123)2.12917094
65Aplasia/Hypoplasia of the sacrum (HP:0008517)2.11256548
66Abnormality of the distal phalanges of the toes (HP:0010182)2.11219328
67Recurrent gram-negative bacterial infections (HP:0005420)2.10292338
68Upper motor neuron abnormality (HP:0002127)2.06614996
69Progressive neurologic deterioration (HP:0002344)2.06321227
70Nonimmune hydrops fetalis (HP:0001790)2.04373424
71Albinism (HP:0001022)2.03994909
72Protrusio acetabuli (HP:0003179)2.03063454
73Metaphyseal irregularity (HP:0003025)2.02390957
74Iris hypopigmentation (HP:0007730)2.01447289
75Abnormality of the intrinsic pathway (HP:0010989)1.98753773
76Joint hemorrhage (HP:0005261)1.97440022
77Vascular calcification (HP:0004934)1.96280543
78Aplasia/Hypoplasia affecting the retina (HP:0008061)1.95791679
79Loss of speech (HP:0002371)1.95314710
80Orchitis (HP:0100796)1.94868295
81Hyperglycinuria (HP:0003108)1.94085036
82Myocardial infarction (HP:0001658)1.93145345
83Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.92620373
84Partial duplication of thumb phalanx (HP:0009944)1.92581227
85Zonular cataract (HP:0010920)1.92037934
86Abnormal cartilage morphology (HP:0002763)1.91874013
87Pathologic fracture (HP:0002756)1.91721751
88Urticaria (HP:0001025)1.89876645
89Cardiovascular calcification (HP:0011915)1.88775912
90Autoimmune thrombocytopenia (HP:0001973)1.88478087
91Asymmetric septal hypertrophy (HP:0001670)1.88092478
92Hydroxyprolinuria (HP:0003080)1.88076361
93Abnormality of proline metabolism (HP:0010907)1.88076361
94Mitral stenosis (HP:0001718)1.87949669
95Prolonged partial thromboplastin time (HP:0003645)1.86778455
96Abnormality of the vasculature of the conjunctiva (HP:0008054)1.86704532
97Generalized aminoaciduria (HP:0002909)1.85957947
98Premature loss of primary teeth (HP:0006323)1.85763072
99Recurrent skin infections (HP:0001581)1.85597171
100Partial duplication of the phalanx of hand (HP:0009999)1.85590696
101Increased serum ferritin (HP:0003281)1.84584671
102Prolonged neonatal jaundice (HP:0006579)1.84220090
103Diminished motivation (HP:0000745)1.84151217
104Abnormality of the Achilles tendon (HP:0005109)1.83498703
105Thoracic kyphosis (HP:0002942)1.83462487
106Beaking of vertebral bodies (HP:0004568)1.82253497
107Achilles tendon contracture (HP:0001771)1.80888020
108Intrahepatic cholestasis (HP:0001406)1.80535902
109Hypokinesia (HP:0002375)1.79706944
110Skin nodule (HP:0200036)1.79511500
111Abnormality of alkaline phosphatase activity (HP:0004379)1.78620246
112Hematochezia (HP:0002573)1.77464891
113Osteolytic defects of the phalanges of the hand (HP:0009771)1.77251254
114Osteolytic defects of the hand bones (HP:0009699)1.77251254
115Abnormal enzyme/coenzyme activity (HP:0012379)1.77163093
116Apathy (HP:0000741)1.76203301
117Dementia (HP:0000726)1.76054410
118Testicular atrophy (HP:0000029)1.75108755
119Bone pain (HP:0002653)1.73984922
120Periodontitis (HP:0000704)1.73701938
121Abnormal trabecular bone morphology (HP:0100671)1.73306917
122Sparse eyelashes (HP:0000653)1.73061044
123Hand muscle atrophy (HP:0009130)1.72771653
124Spondylolisthesis (HP:0003302)1.72731126
125Abnormality of the nasal mucosa (HP:0000433)1.71389793
126Peripheral demyelination (HP:0011096)1.68792473
127Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.68754375
128Abnormal protein N-linked glycosylation (HP:0012347)1.68754375
129Abnormal protein glycosylation (HP:0012346)1.68754375
130Abnormal glycosylation (HP:0012345)1.68754375
131Neoplasm of head and neck (HP:0012288)1.68413276
132Esophageal neoplasm (HP:0100751)1.68413276
133Nasal polyposis (HP:0100582)1.67537584
134Elevated alkaline phosphatase (HP:0003155)1.66640448
135Abnormality of the fovea (HP:0000493)1.66197712
136Gout (HP:0001997)1.65981774
137Rough bone trabeculation (HP:0100670)1.65511650
138Cerebral inclusion bodies (HP:0100314)1.63882783
139Nausea (HP:0002018)1.63518147
140Generalized hypopigmentation (HP:0007513)1.62863066
141Joint stiffness (HP:0001387)1.62444560
142Abnormality of the costochondral junction (HP:0000919)1.60935657
143Protuberant abdomen (HP:0001538)1.60764875
144Proximal tubulopathy (HP:0000114)1.57724346
145Xanthomatosis (HP:0000991)1.57688871
146Obstructive lung disease (HP:0006536)1.57531744
147Chronic obstructive pulmonary disease (HP:0006510)1.57531744
148Generalized amyotrophy (HP:0003700)1.56604276
149Microretrognathia (HP:0000308)1.56549968
150Restrictive lung disease (HP:0002091)1.56448408
151Glomerulonephritis (HP:0000099)1.55813860
152Abdominal distention (HP:0003270)1.55373994
153Anorexia (HP:0002039)1.54765673
154Recurrent fungal infections (HP:0002841)1.53629591
155Gingival bleeding (HP:0000225)1.53356329
1563-Methylglutaconic aciduria (HP:0003535)1.53119302
157Abnormality of iron homeostasis (HP:0011031)1.51816688

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN15.20512364
2BLK3.27575812
3EPHA23.23608683
4CDK123.13477936
5IRAK32.95564923
6TGFBR22.76199754
7NME22.29166856
8GRK62.19651055
9TAOK22.15710365
10CSF1R2.10283018
11ACVR1B1.97574100
12STK101.96547191
13PIM21.93967528
14GRK11.88264559
15LIMK11.85378866
16TESK21.82515149
17VRK21.75910853
18ADRBK21.73800633
19RIPK11.70981897
20TBK11.70165317
21MAPKAPK31.68097001
22MAP4K11.66797663
23KIT1.65592395
24KDR1.62168821
25PAK41.61111288
26GRK51.57346742
27PDK21.57133371
28EPHB11.57102977
29TRIB31.53316293
30MST41.51981204
31MATK1.46106996
32BUB11.43705685
33IRAK41.39104451
34TYK21.35363911
35PBK1.31566144
36CSK1.31043981
37CAMK1D1.29507367
38IKBKB1.28809642
39ZAP701.27627290
40EPHB21.24217906
41PRKD21.23318140
42MAPK71.18996542
43NEK91.17108563
44TGFBR11.16802328
45CDC42BPA1.16352340
46MST1R1.15354320
47LRRK21.15230288
48BCKDK1.14937941
49PRKG21.10891094
50MOS1.10389478
51GRK71.09090129
52FGFR41.07801465
53TAOK31.05261826
54RPS6KA41.03700670
55MET0.99383000
56FGR0.96293766
57ICK0.95815483
58MAP3K140.95399320
59JAK30.94609200
60PDGFRA0.93498941
61AKT30.93379606
62EPHA30.93272991
63ITK0.92303891
64MARK30.92254965
65BMX0.87852783
66MAP3K30.87659436
67SIK10.86768652
68TIE10.85976785
69TYRO30.85373388
70IKBKE0.84346003
71PIK3CG0.83495932
72TTK0.82750510
73MAP2K20.82596150
74CAMKK20.82372259
75SIK30.81714799
76MAP2K60.80723177
77TAOK10.80189501
78ERBB40.79772286
79DDR20.78825588
80TXK0.75114437
81LMTK20.73033754
82CDK70.72022186
83PTK20.71102802
84TESK10.69838947
85JAK10.69731376
86GSK3A0.67493889
87TLK10.67221993
88EIF2AK20.64749272
89SMG10.60192325
90BTK0.59131557
91PRKCD0.57293368
92RPS6KA20.57203919
93ABL20.56617296
94PIM10.55722513
95PRPF4B0.55694518
96WNK10.54487047
97LYN0.54460776
98HCK0.54007187
99MAP3K120.53337602
100FLT30.53309149
101TEC0.52610085
102PDPK10.52572226
103LCK0.52502488
104EIF2AK10.51612909
105IRAK10.50168054
106FGFR30.49842799
107MAPK150.49462165
108CAMK1G0.48390657
109NUAK10.48336445
110PAK10.48066144
111EIF2AK30.47238503
112CHUK0.47019782
113MYLK0.46938048
114TNK20.46512205
115MAP3K110.46452664
116IGF1R0.46269475
117NLK0.45627896
118PTK60.44401496
119TRPM70.42798975
120PRKCI0.40212353
121HIPK20.39582098
122MAPKAPK20.39034673
123MAP3K10.38481418
124IRAK20.37459890
125MAP2K30.36760993
126MAP3K80.36244437
127SYK0.33681757
128ABL10.33542313
129JAK20.33396830
130ILK0.31212607
131ADRBK10.30581772
132MAPK120.30320627
133PINK10.29886120
134DAPK30.29490779
135RPS6KL10.29470354
136RPS6KC10.29470354
137STK160.29357440
138ARAF0.29202515
139CSNK1G30.28794066
140CAMK40.28696103
141EGFR0.27891837
142RPS6KA60.26607699

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005113.67218751
2Glycosaminoglycan degradation_Homo sapiens_hsa005313.20805261
3Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006033.12575539
4Lysosome_Homo sapiens_hsa041423.03392074
5Primary bile acid biosynthesis_Homo sapiens_hsa001202.55748870
6Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.44392435
7Vitamin B6 metabolism_Homo sapiens_hsa007502.40716596
8Fructose and mannose metabolism_Homo sapiens_hsa000512.10203192
9Pentose and glucuronate interconversions_Homo sapiens_hsa000401.96195738
10Staphylococcus aureus infection_Homo sapiens_hsa051501.87144538
11Galactose metabolism_Homo sapiens_hsa000521.84016973
12Folate biosynthesis_Homo sapiens_hsa007901.74181702
13Collecting duct acid secretion_Homo sapiens_hsa049661.66442919
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.66266726
15Arachidonic acid metabolism_Homo sapiens_hsa005901.63907657
16Malaria_Homo sapiens_hsa051441.54372774
17Steroid biosynthesis_Homo sapiens_hsa001001.50420054
18Leishmaniasis_Homo sapiens_hsa051401.48725457
19Prion diseases_Homo sapiens_hsa050201.44805529
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42236976
21Vibrio cholerae infection_Homo sapiens_hsa051101.40687541
22Ribosome_Homo sapiens_hsa030101.30085423
23Legionellosis_Homo sapiens_hsa051341.29197310
24Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.28611406
25Sphingolipid metabolism_Homo sapiens_hsa006001.26207245
26Antigen processing and presentation_Homo sapiens_hsa046121.18811342
27Pentose phosphate pathway_Homo sapiens_hsa000301.18607212
28NF-kappa B signaling pathway_Homo sapiens_hsa040641.17785161
29Proteasome_Homo sapiens_hsa030501.17509718
30Complement and coagulation cascades_Homo sapiens_hsa046101.16813708
31Protein export_Homo sapiens_hsa030601.16656499
32Tyrosine metabolism_Homo sapiens_hsa003501.13029353
33Renin-angiotensin system_Homo sapiens_hsa046141.12504841
34Intestinal immune network for IgA production_Homo sapiens_hsa046721.11619394
35Oxidative phosphorylation_Homo sapiens_hsa001901.11232456
36Vitamin digestion and absorption_Homo sapiens_hsa049771.11042289
37N-Glycan biosynthesis_Homo sapiens_hsa005101.09796552
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08770543
39Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.07675752
40Rheumatoid arthritis_Homo sapiens_hsa053231.04596139
41Pertussis_Homo sapiens_hsa051331.02633604
42RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.01507300
43Hematopoietic cell lineage_Homo sapiens_hsa046400.99154245
44Histidine metabolism_Homo sapiens_hsa003400.99055843
45Phagosome_Homo sapiens_hsa041450.96449376
46Tuberculosis_Homo sapiens_hsa051520.96319272
47Leukocyte transendothelial migration_Homo sapiens_hsa046700.95472248
48Toll-like receptor signaling pathway_Homo sapiens_hsa046200.94700740
49Cyanoamino acid metabolism_Homo sapiens_hsa004600.94162647
50Sulfur relay system_Homo sapiens_hsa041220.92530244
51Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.91944588
52Regulation of autophagy_Homo sapiens_hsa041400.91790230
53Glutathione metabolism_Homo sapiens_hsa004800.91586004
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91511383
55Apoptosis_Homo sapiens_hsa042100.91200562
56Caffeine metabolism_Homo sapiens_hsa002320.90121839
57Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.89282206
58Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.84797663
59alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.83815496
60Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.81561979
61Linoleic acid metabolism_Homo sapiens_hsa005910.79666460
62Peroxisome_Homo sapiens_hsa041460.78605743
63Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.78084903
64Chemical carcinogenesis_Homo sapiens_hsa052040.77165120
65Primary immunodeficiency_Homo sapiens_hsa053400.73848241
66Measles_Homo sapiens_hsa051620.72625485
67Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.72615056
68Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.72108438
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.71526813
70Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.71038095
71Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69522487
72Tryptophan metabolism_Homo sapiens_hsa003800.69439105
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.68022904
74Mineral absorption_Homo sapiens_hsa049780.67930465
75Osteoclast differentiation_Homo sapiens_hsa043800.67469235
76Salmonella infection_Homo sapiens_hsa051320.67431059
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66339252
78Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65277333
79p53 signaling pathway_Homo sapiens_hsa041150.65071534
80Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64404817
81Fatty acid degradation_Homo sapiens_hsa000710.62602210
82Graft-versus-host disease_Homo sapiens_hsa053320.62417915
83Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.61689615
84Drug metabolism - other enzymes_Homo sapiens_hsa009830.61058644
85Fatty acid elongation_Homo sapiens_hsa000620.61025625
86Starch and sucrose metabolism_Homo sapiens_hsa005000.60542322
87Herpes simplex infection_Homo sapiens_hsa051680.59311101
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59128216
89Toxoplasmosis_Homo sapiens_hsa051450.59088545
90Shigellosis_Homo sapiens_hsa051310.58796724
91Hepatitis C_Homo sapiens_hsa051600.57141568
92Allograft rejection_Homo sapiens_hsa053300.55852863
93Sulfur metabolism_Homo sapiens_hsa009200.55685372
94Arginine and proline metabolism_Homo sapiens_hsa003300.54220969
95Influenza A_Homo sapiens_hsa051640.54192472
96Jak-STAT signaling pathway_Homo sapiens_hsa046300.52858381
97Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.52850600
98NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51515472
99PPAR signaling pathway_Homo sapiens_hsa033200.51485575
100Amoebiasis_Homo sapiens_hsa051460.51400452
101Bladder cancer_Homo sapiens_hsa052190.50127664
102Autoimmune thyroid disease_Homo sapiens_hsa053200.49633478
103beta-Alanine metabolism_Homo sapiens_hsa004100.48818356
104Ether lipid metabolism_Homo sapiens_hsa005650.48620843
105ECM-receptor interaction_Homo sapiens_hsa045120.48016521
106RNA polymerase_Homo sapiens_hsa030200.47378278
107Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47039620
108Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46594436
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46041055
110Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.45089124
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.44865338
112Selenocompound metabolism_Homo sapiens_hsa004500.43613731
113Retinol metabolism_Homo sapiens_hsa008300.43542033
114Cysteine and methionine metabolism_Homo sapiens_hsa002700.42315507
115Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.42252830
116Fat digestion and absorption_Homo sapiens_hsa049750.41473267
117Carbon metabolism_Homo sapiens_hsa012000.41278129
118Arginine biosynthesis_Homo sapiens_hsa002200.40828961
119Metabolic pathways_Homo sapiens_hsa011000.40017314
1202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.39968840
121TNF signaling pathway_Homo sapiens_hsa046680.39439091
122Asthma_Homo sapiens_hsa053100.38668422
123Biosynthesis of amino acids_Homo sapiens_hsa012300.38621644
124Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.38463042
125Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38373366
126Maturity onset diabetes of the young_Homo sapiens_hsa049500.38212922
127SNARE interactions in vesicular transport_Homo sapiens_hsa041300.38039750
128African trypanosomiasis_Homo sapiens_hsa051430.34342532
129Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.32828569

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