GLOD4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)8.95298598
2axon ensheathment in central nervous system (GO:0032291)8.95298598
3fatty acid elongation (GO:0030497)6.75625405
4ensheathment of neurons (GO:0007272)4.92895002
5axon ensheathment (GO:0008366)4.92895002
6myelination (GO:0042552)4.89194211
7cholesterol biosynthetic process (GO:0006695)4.73121824
8myelin maintenance (GO:0043217)4.35962073
9regulation of mitochondrial translation (GO:0070129)4.30497166
10sterol biosynthetic process (GO:0016126)4.14277033
11long-chain fatty acid biosynthetic process (GO:0042759)4.02070410
12protein complex biogenesis (GO:0070271)3.96537220
13establishment of protein localization to mitochondrial membrane (GO:0090151)3.95490133
14L-serine metabolic process (GO:0006563)3.94956067
15respiratory chain complex IV assembly (GO:0008535)3.90196203
16mitochondrial respiratory chain complex assembly (GO:0033108)3.85393832
17mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.82497736
18nucleotide transmembrane transport (GO:1901679)3.78505790
19L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.72586373
20DNA damage response, detection of DNA damage (GO:0042769)3.66318556
21ribosomal small subunit assembly (GO:0000028)3.65444925
22proteasome assembly (GO:0043248)3.63830743
23water-soluble vitamin biosynthetic process (GO:0042364)3.60915655
24creatine metabolic process (GO:0006600)3.60643666
25electron transport chain (GO:0022900)3.54651263
26nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.52788393
27pseudouridine synthesis (GO:0001522)3.51763022
28establishment of viral latency (GO:0019043)3.50809083
29isoprenoid biosynthetic process (GO:0008299)3.49900737
30GPI anchor biosynthetic process (GO:0006506)3.49785900
31cotranslational protein targeting to membrane (GO:0006613)3.47550934
32energy coupled proton transport, down electrochemical gradient (GO:0015985)3.44610748
33ATP synthesis coupled proton transport (GO:0015986)3.44610748
34spliceosomal snRNP assembly (GO:0000387)3.43703037
35exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.43645788
36chaperone-mediated protein transport (GO:0072321)3.41466574
37cytochrome complex assembly (GO:0017004)3.41050950
38DNA unwinding involved in DNA replication (GO:0006268)3.39433509
39DNA ligation (GO:0006266)3.38887180
40protein targeting to ER (GO:0045047)3.38458712
41SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.34933481
42amyloid precursor protein metabolic process (GO:0042982)3.33704756
43long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.31940375
44protein localization to endoplasmic reticulum (GO:0070972)3.31626283
45DNA deamination (GO:0045006)3.30981908
46viral transcription (GO:0019083)3.30750332
47signal peptide processing (GO:0006465)3.30427829
48substantia nigra development (GO:0021762)3.29370197
49chromatin remodeling at centromere (GO:0031055)3.28411063
50ribosomal small subunit biogenesis (GO:0042274)3.26888353
51establishment of protein localization to endoplasmic reticulum (GO:0072599)3.26449015
52protein-cofactor linkage (GO:0018065)3.24384427
53negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.23864555
54CENP-A containing nucleosome assembly (GO:0034080)3.23442785
55translational termination (GO:0006415)3.23262758
56transcription elongation from RNA polymerase III promoter (GO:0006385)3.22484206
57termination of RNA polymerase III transcription (GO:0006386)3.22484206
58oxidative phosphorylation (GO:0006119)3.21367917
59DNA double-strand break processing (GO:0000729)3.19300812
60negative regulation of ligase activity (GO:0051352)3.16924307
61negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.16924307
62positive regulation of cellular amine metabolic process (GO:0033240)3.15888783
63mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.12599371
64apical protein localization (GO:0045176)3.12453691
65DNA strand elongation involved in DNA replication (GO:0006271)3.11953394
66long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.10578547
67cullin deneddylation (GO:0010388)3.10084640
68L-methionine salvage (GO:0071267)3.08657905
69L-methionine biosynthetic process (GO:0071265)3.08657905
70amino acid salvage (GO:0043102)3.08657905
71protein neddylation (GO:0045116)3.08597939
72GPI anchor metabolic process (GO:0006505)3.07801434
73rRNA modification (GO:0000154)3.07683738
74protein targeting to mitochondrion (GO:0006626)3.05643146
75protein deneddylation (GO:0000338)3.05633821
76regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.04695352
77regulation of mitotic spindle checkpoint (GO:1903504)3.04695352
78DNA catabolic process, exonucleolytic (GO:0000738)3.03778101
79serine family amino acid biosynthetic process (GO:0009070)3.03230461
80maturation of SSU-rRNA (GO:0030490)3.02991161
81mannosylation (GO:0097502)3.02750442
82positive regulation of oligodendrocyte differentiation (GO:0048714)3.02453908
83viral mRNA export from host cell nucleus (GO:0046784)3.01798071
84establishment of integrated proviral latency (GO:0075713)3.01261969
85aldehyde catabolic process (GO:0046185)2.98947393
86oligodendrocyte differentiation (GO:0048709)2.96713712
87regulation of collateral sprouting (GO:0048670)2.96541353
88signal transduction involved in cell cycle checkpoint (GO:0072395)2.96062443
89mitochondrial RNA metabolic process (GO:0000959)2.95952366
90establishment of mitochondrion localization (GO:0051654)2.95637585
91DNA strand elongation (GO:0022616)2.95226927
92amyloid precursor protein catabolic process (GO:0042987)2.95086969
93mitotic nuclear envelope reassembly (GO:0007084)2.95016489
94nuclear envelope reassembly (GO:0031468)2.95016489
95fatty-acyl-CoA biosynthetic process (GO:0046949)2.94812547
96inner mitochondrial membrane organization (GO:0007007)2.93849518
97establishment of protein localization to mitochondrion (GO:0072655)2.92897200
98fatty-acyl-CoA metabolic process (GO:0035337)2.90965201
99positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.90956909
100regulation of cellular amino acid metabolic process (GO:0006521)2.90868483
101tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.90745854
102RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.90745854
103very long-chain fatty acid metabolic process (GO:0000038)2.90220553
104translational elongation (GO:0006414)2.88712781
105negative regulation of neurotransmitter secretion (GO:0046929)2.88463297
106preassembly of GPI anchor in ER membrane (GO:0016254)2.88452825
107asymmetric protein localization (GO:0008105)2.87108208
108replication fork processing (GO:0031297)2.85861923
109protein localization to mitochondrion (GO:0070585)2.85464848
110positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.85349253
111regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.83658745
112erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.83479781
113L-phenylalanine catabolic process (GO:0006559)2.83479781
114adhesion of symbiont to host cell (GO:0044650)2.82342826
115virion attachment to host cell (GO:0019062)2.82342826
116DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.81582046
117tRNA processing (GO:0008033)2.79177988
118astrocyte development (GO:0014002)2.78353358
119positive regulation of ligase activity (GO:0051351)2.78026201
120maturation of 5.8S rRNA (GO:0000460)2.78003247
121peptidyl-histidine modification (GO:0018202)2.77258045
122intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.77200409
123signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.77200409
124mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.76182560
125mitochondrial respiratory chain complex I assembly (GO:0032981)2.76182560
126NADH dehydrogenase complex assembly (GO:0010257)2.76182560
127translation (GO:0006412)2.74366016
128telomere maintenance via semi-conservative replication (GO:0032201)2.74283075
129tRNA metabolic process (GO:0006399)2.74044827
130glycerophospholipid catabolic process (GO:0046475)2.73473394
131somatic hypermutation of immunoglobulin genes (GO:0016446)2.73019784
132somatic diversification of immune receptors via somatic mutation (GO:0002566)2.73019784
133pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.71299897
134anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.71197379
135signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.71036122
136signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.71036122
137signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.71036122
1387-methylguanosine mRNA capping (GO:0006370)2.70911232
139histone exchange (GO:0043486)2.70604303
140protein localization to kinetochore (GO:0034501)2.70401833
141respiratory electron transport chain (GO:0022904)2.68019593
142amino acid activation (GO:0043038)2.68018969
143tRNA aminoacylation (GO:0043039)2.68018969
144viral life cycle (GO:0019058)2.67268502
145tRNA aminoacylation for protein translation (GO:0006418)2.66770317
146antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.66117652
147signal transduction involved in DNA integrity checkpoint (GO:0072401)2.65463000
148signal transduction involved in DNA damage checkpoint (GO:0072422)2.65463000
149nucleobase biosynthetic process (GO:0046112)2.63632534
1507-methylguanosine RNA capping (GO:0009452)2.62471300
151RNA capping (GO:0036260)2.62471300
152rRNA processing (GO:0006364)2.61194125
153base-excision repair, AP site formation (GO:0006285)2.58975378
154regulation of ubiquitin-protein transferase activity (GO:0051438)2.58390671
155hydrogen ion transmembrane transport (GO:1902600)2.58122891
156cellular component biogenesis (GO:0044085)2.57325117
157transcription-coupled nucleotide-excision repair (GO:0006283)2.56251102
158rRNA metabolic process (GO:0016072)2.55367241
159ribosomal large subunit biogenesis (GO:0042273)2.54923388

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.33183662
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.61116987
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.40744884
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.12500894
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.99150048
6E2F7_22180533_ChIP-Seq_HELA_Human3.77730453
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.77152421
8MYC_18555785_ChIP-Seq_MESCs_Mouse3.75982284
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.53847253
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.49078707
11* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.42214968
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.33944853
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.20842687
14ETS1_20019798_ChIP-Seq_JURKAT_Human3.16771238
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.08318874
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.82825211
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.72619462
18PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.72218827
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.69789572
20* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.53633198
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.47569425
22E2F1_18555785_ChIP-Seq_MESCs_Mouse2.42554337
23MYC_19079543_ChIP-ChIP_MESCs_Mouse2.33419413
24THAP11_20581084_ChIP-Seq_MESCs_Mouse2.31198758
25SRF_21415370_ChIP-Seq_HL-1_Mouse2.24357291
26* VDR_23849224_ChIP-Seq_CD4+_Human2.23977780
27ZNF274_21170338_ChIP-Seq_K562_Hela2.22151755
28* XRN2_22483619_ChIP-Seq_HELA_Human2.16848480
29DCP1A_22483619_ChIP-Seq_HELA_Human2.05162986
30* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.89769706
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.89469453
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.88209955
33FOXP3_21729870_ChIP-Seq_TREG_Human1.87826581
34* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.83211361
35* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.81386424
36HOXB4_20404135_ChIP-ChIP_EML_Mouse1.78653173
37CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.78325259
38AR_21909140_ChIP-Seq_LNCAP_Human1.76284382
39ERG_20887958_ChIP-Seq_HPC-7_Mouse1.73307577
40ELK1_19687146_ChIP-ChIP_HELA_Human1.71518048
41NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67235366
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.64630300
43GABP_19822575_ChIP-Seq_HepG2_Human1.62147893
44CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.62109120
45E2F4_17652178_ChIP-ChIP_JURKAT_Human1.57950418
46ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.57443387
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.53275057
48TTF2_22483619_ChIP-Seq_HELA_Human1.50264682
49SOX17_20123909_ChIP-Seq_XEN_Mouse1.48221424
50FUS_26573619_Chip-Seq_HEK293_Human1.46535589
51FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.44307235
52EWS_26573619_Chip-Seq_HEK293_Human1.43775931
53TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41212298
54IRF1_19129219_ChIP-ChIP_H3396_Human1.40527885
55CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.40180860
56IGF1R_20145208_ChIP-Seq_DFB_Human1.40164431
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.39690881
58VDR_22108803_ChIP-Seq_LS180_Human1.38654376
59FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38088203
60SALL1_21062744_ChIP-ChIP_HESCs_Human1.35668635
61SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.27604140
62KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.26805600
63* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.23031076
64* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.22544984
65ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.22330903
66MYC_18940864_ChIP-ChIP_HL60_Human1.18430844
67ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.17899757
68CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.17680813
69HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.16631262
70PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14625725
71CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.12757478
72CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.10786501
73PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.09748291
74YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09584357
75FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.09082863
76PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.07617379
77* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.07068208
78FOXM1_23109430_ChIP-Seq_U2OS_Human1.06696474
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.06573806
80EGR1_23403033_ChIP-Seq_LIVER_Mouse1.05483927
81* CIITA_25753668_ChIP-Seq_RAJI_Human1.04920808
82E2F1_21310950_ChIP-Seq_MCF-7_Human1.04607746
83POU3F2_20337985_ChIP-ChIP_501MEL_Human1.03112472
84KDM5A_27292631_Chip-Seq_BREAST_Human1.01335484
85SOX2_16153702_ChIP-ChIP_HESCs_Human1.01283620
86TP53_22573176_ChIP-Seq_HFKS_Human1.00392221
87SOX2_18692474_ChIP-Seq_MEFs_Mouse1.00098193
88DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.97723761
89NANOG_16153702_ChIP-ChIP_HESCs_Human0.97653609
90SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97456237
91NOTCH1_21737748_ChIP-Seq_TLL_Human0.96353590
92FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95123525
93EOMES_21245162_ChIP-Seq_HESCs_Human0.95053454
94TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.94904367
95SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.94605863
96ELK1_22589737_ChIP-Seq_MCF10A_Human0.94371404
97CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.94186986
98POU5F1_16153702_ChIP-ChIP_HESCs_Human0.93764973
99PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92342552
100SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.92246100
101SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.90726177
102NANOG_18555785_ChIP-Seq_MESCs_Mouse0.88385479
103FLI1_27457419_Chip-Seq_LIVER_Mouse0.88178023
104BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.88165193
105ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.87725175
106CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.86231284
107POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.85331557
108CTBP1_25329375_ChIP-Seq_LNCAP_Human0.85052221
109TFEB_21752829_ChIP-Seq_HELA_Human0.84118298
110SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.84064154
111EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.83729865
112SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.83345304
113ZFP57_27257070_Chip-Seq_ESCs_Mouse0.82868807
114P300_19829295_ChIP-Seq_ESCs_Human0.82588318
115EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.82363546
116GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79035486
117TAF15_26573619_Chip-Seq_HEK293_Human0.78757737
118FOXA1_25329375_ChIP-Seq_VCAP_Human0.78594661
119FOXA1_27270436_Chip-Seq_PROSTATE_Human0.78594661
120CTBP2_25329375_ChIP-Seq_LNCAP_Human0.78243033
121KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.77747419
122KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.77747419
123KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.77747419
124MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.77114864
125AR_20517297_ChIP-Seq_VCAP_Human0.77094834
126HTT_18923047_ChIP-ChIP_STHdh_Human0.76890099
127TBX5_21415370_ChIP-Seq_HL-1_Mouse0.76771844
128TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.75925948
129STAT1_20625510_ChIP-Seq_HELA_Human0.73047082
130WT1_19549856_ChIP-ChIP_CCG9911_Human0.71983843
131YY1_22570637_ChIP-Seq_MALME-3M_Human0.71877295
132POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.71054915
133HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.70659904
134TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.69813809

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis5.96285384
2MP0000920_abnormal_myelination4.73425563
3MP0003136_yellow_coat_color3.28229896
4MP0003950_abnormal_plasma_membrane3.24221807
5MP0002822_catalepsy2.98763835
6MP0001529_abnormal_vocalization2.66681206
7MP0004147_increased_porphyrin_level2.55373201
8MP0008789_abnormal_olfactory_epithelium2.50680531
9MP0008057_abnormal_DNA_replication2.44377132
10MP0006072_abnormal_retinal_apoptosis2.42295243
11MP0003186_abnormal_redox_activity2.30013649
12MP0005171_absent_coat_pigmentation2.28106407
13MP0004381_abnormal_hair_follicle2.24068389
14MP0005408_hypopigmentation2.17617751
15MP0008932_abnormal_embryonic_tissue2.16864442
16MP0004957_abnormal_blastocyst_morpholog2.13609135
17MP0001905_abnormal_dopamine_level2.13162222
18MP0000566_synostosis2.09941120
19MP0005499_abnormal_olfactory_system2.04018151
20MP0005394_taste/olfaction_phenotype2.04018151
21MP0003122_maternal_imprinting2.03693207
22MP0003690_abnormal_glial_cell1.96016029
23MP0008877_abnormal_DNA_methylation1.95756750
24MP0000383_abnormal_hair_follicle1.94247599
25MP0005409_darkened_coat_color1.94194194
26MP0004142_abnormal_muscle_tone1.89339234
27MP0001984_abnormal_olfaction1.88835044
28MP0002736_abnormal_nociception_after1.88512832
29MP0002234_abnormal_pharynx_morphology1.86590675
30MP0010678_abnormal_skin_adnexa1.84265813
31MP0001485_abnormal_pinna_reflex1.82098855
32MP0004885_abnormal_endolymph1.79051588
33MP0003121_genomic_imprinting1.78447551
34MP0004134_abnormal_chest_morphology1.78069685
35MP0005075_abnormal_melanosome_morpholog1.77145745
36MP0003011_delayed_dark_adaptation1.75961593
37MP0002653_abnormal_ependyma_morphology1.68581589
38MP0003195_calcinosis1.68324849
39MP0010094_abnormal_chromosome_stability1.65836468
40MP0006292_abnormal_olfactory_placode1.64808178
41MP0001661_extended_life_span1.64507795
42MP0006036_abnormal_mitochondrial_physio1.64449624
43MP0005253_abnormal_eye_physiology1.62811481
44MP0010030_abnormal_orbit_morphology1.61147638
45MP0008260_abnormal_autophagy1.60544461
46MP0009379_abnormal_foot_pigmentation1.60445416
47MP0005084_abnormal_gallbladder_morpholo1.56889439
48MP0002938_white_spotting1.54959574
49MP0004043_abnormal_pH_regulation1.53147946
50MP0003634_abnormal_glial_cell1.52398321
51MP0003077_abnormal_cell_cycle1.48754249
52MP0000372_irregular_coat_pigmentation1.46232296
53MP0003718_maternal_effect1.44856148
54MP0004133_heterotaxia1.44600175
55MP0002638_abnormal_pupillary_reflex1.43866111
56MP0002909_abnormal_adrenal_gland1.42068450
57MP0003786_premature_aging1.41159200
58MP0005551_abnormal_eye_electrophysiolog1.40602760
59MP0003937_abnormal_limbs/digits/tail_de1.38377776
60MP0009697_abnormal_copulation1.37053635
61MP0000462_abnormal_digestive_system1.35032041
62MP0003567_abnormal_fetal_cardiomyocyte1.34186137
63MP0004742_abnormal_vestibular_system1.34059840
64MP0003119_abnormal_digestive_system1.33824860
65MP0005410_abnormal_fertilization1.33267270
66MP0000762_abnormal_tongue_morphology1.32569954
67MP0005451_abnormal_body_composition1.27910700
68MP0001293_anophthalmia1.25132046
69MP0006276_abnormal_autonomic_nervous1.25085761
70MP0008875_abnormal_xenobiotic_pharmacok1.23559370
71MP0008058_abnormal_DNA_repair1.23544547
72MP0000537_abnormal_urethra_morphology1.21587545
73MP0000465_gastrointestinal_hemorrhage1.20780893
74MP0009840_abnormal_foam_cell1.18512742
75MP0005083_abnormal_biliary_tract1.18454132
76MP0000631_abnormal_neuroendocrine_gland1.16622555
77MP0003329_amyloid_beta_deposits1.16090669
78MP0001730_embryonic_growth_arrest1.15166885
79MP0001968_abnormal_touch/_nociception1.15085426
80MP0005367_renal/urinary_system_phenotyp1.14518391
81MP0000516_abnormal_urinary_system1.14518391
82MP0005646_abnormal_pituitary_gland1.13153343
83MP0003632_abnormal_nervous_system1.12968842
84MP0000613_abnormal_salivary_gland1.10890610
85MP0001346_abnormal_lacrimal_gland1.10357433
86MP0005332_abnormal_amino_acid1.07300152
87MP0003880_abnormal_central_pattern1.06847739
88MP0002229_neurodegeneration1.06061309
89MP0005058_abnormal_lysosome_morphology1.06061269
90MP0000747_muscle_weakness1.03826709
91MP0000467_abnormal_esophagus_morphology1.02913215
92MP0008872_abnormal_physiological_respon1.02755651
93MP0005645_abnormal_hypothalamus_physiol1.01511682
94MP0008007_abnormal_cellular_replicative0.98527438
95MP0009765_abnormal_xenobiotic_induced0.98384571
96MP0002233_abnormal_nose_morphology0.97185369
97MP0002139_abnormal_hepatobiliary_system0.96801320
98MP0001727_abnormal_embryo_implantation0.94014131
99MP0005391_vision/eye_phenotype0.93261212
100MP0002090_abnormal_vision0.92941103
101MP0001929_abnormal_gametogenesis0.92878963
102MP0001851_eye_inflammation0.91465016
103MP0000647_abnormal_sebaceous_gland0.90120245
104MP0001188_hyperpigmentation0.89169806
105MP0002876_abnormal_thyroid_physiology0.89118941
106MP0009046_muscle_twitch0.87781141
107MP0001348_abnormal_lacrimal_gland0.87505930
108MP0002210_abnormal_sex_determination0.86991917
109MP0003111_abnormal_nucleus_morphology0.86907759
110MP0005584_abnormal_enzyme/coenzyme_acti0.86793700
111MP0002735_abnormal_chemical_nociception0.85889648
112MP0003693_abnormal_embryo_hatching0.85704594
113MP0003656_abnormal_erythrocyte_physiolo0.82299985
114MP0002933_joint_inflammation0.81546176
115MP0003283_abnormal_digestive_organ0.81462717
116MP0000358_abnormal_cell_content/0.81117839
117MP0000778_abnormal_nervous_system0.81021745
118MP0002396_abnormal_hematopoietic_system0.78966072
119MP0001145_abnormal_male_reproductive0.78716508
120MP0003787_abnormal_imprinting0.78379301
121MP0005085_abnormal_gallbladder_physiolo0.77628280
122MP0001324_abnormal_eye_pigmentation0.77191144
123MP0000049_abnormal_middle_ear0.76512948
124MP0008438_abnormal_cutaneous_collagen0.76511242
125MP0000653_abnormal_sex_gland0.75685934
126MP0005195_abnormal_posterior_eye0.75529636
127MP0003698_abnormal_male_reproductive0.75311228
128MP0006054_spinal_hemorrhage0.75088067
129MP0006035_abnormal_mitochondrial_morpho0.75054690
130MP0008995_early_reproductive_senescence0.74458778
131MP0009745_abnormal_behavioral_response0.74215458
132MP0000377_abnormal_hair_follicle0.73723880
133MP0001286_abnormal_eye_development0.73408595
134MP0002102_abnormal_ear_morphology0.71795156
135MP0005395_other_phenotype0.71151857
136MP0003315_abnormal_perineum_morphology0.71145113
137MP0004019_abnormal_vitamin_homeostasis0.69543159
138MP0005501_abnormal_skin_physiology0.68864096
139MP0005636_abnormal_mineral_homeostasis0.68834710
140MP0002837_dystrophic_cardiac_calcinosis0.68832235
141MP0001963_abnormal_hearing_physiology0.68495777
142MP0003938_abnormal_ear_development0.66493596
143MP0002095_abnormal_skin_pigmentation0.63709079
144MP0002272_abnormal_nervous_system0.62186711
145MP0001666_abnormal_nutrient_absorption0.61239082
146MP0002098_abnormal_vibrissa_morphology0.60904009
147MP0002132_abnormal_respiratory_system0.60484889
148MP0002111_abnormal_tail_morphology0.59052209
149MP0009333_abnormal_splenocyte_physiolog0.59022603
150MP0001764_abnormal_homeostasis0.58014971
151MP0008873_increased_physiological_sensi0.57265276
152MP0002751_abnormal_autonomic_nervous0.54927418
153MP0001986_abnormal_taste_sensitivity0.54833497
154MP0003724_increased_susceptibility_to0.54286574
155MP0003221_abnormal_cardiomyocyte_apopto0.53936960
156MP0005266_abnormal_metabolism0.53082412
157MP0000427_abnormal_hair_cycle0.52945378

Predicted human phenotypes

RankGene SetZ-score
1Cerebral hypomyelination (HP:0006808)5.37923623
2Abnormality of glycolysis (HP:0004366)4.88644634
3Increased serum pyruvate (HP:0003542)4.88644634
4Degeneration of the lateral corticospinal tracts (HP:0002314)4.38585480
5Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.38585480
6Parakeratosis (HP:0001036)4.19466633
7Leukodystrophy (HP:0002415)3.91141994
8CNS hypomyelination (HP:0003429)3.80333028
9Spastic paraparesis (HP:0002313)3.70138184
10Hepatocellular necrosis (HP:0001404)3.63987826
113-Methylglutaconic aciduria (HP:0003535)3.56559250
12Sensory axonal neuropathy (HP:0003390)3.54616659
13Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.50289431
14Hepatic necrosis (HP:0002605)3.42507693
15Mitochondrial inheritance (HP:0001427)3.22750641
16Acute necrotizing encephalopathy (HP:0006965)3.16784011
17Hyperglycinemia (HP:0002154)3.15879147
18Abnormality of cells of the erythroid lineage (HP:0012130)3.09933317
19Neurofibrillary tangles (HP:0002185)3.04075519
20Acute encephalopathy (HP:0006846)3.01712403
21Increased CSF lactate (HP:0002490)2.96870661
22Abnormal number of erythroid precursors (HP:0012131)2.96158371
23Abnormality of the anterior horn cell (HP:0006802)2.93313961
24Degeneration of anterior horn cells (HP:0002398)2.93313961
25Abnormal auditory evoked potentials (HP:0006958)2.92950936
26Medial flaring of the eyebrow (HP:0010747)2.91834171
27Increased hepatocellular lipid droplets (HP:0006565)2.88836364
28Hypoplastic pelvis (HP:0008839)2.85966516
29Intrahepatic cholestasis (HP:0001406)2.85156585
30Lipid accumulation in hepatocytes (HP:0006561)2.83517169
31Autoamputation (HP:0001218)2.83378961
32Abnormal mitochondria in muscle tissue (HP:0008316)2.83362014
33Peripheral hypomyelination (HP:0007182)2.82294528
34Hepatosplenomegaly (HP:0001433)2.81200715
35Congenital ichthyosiform erythroderma (HP:0007431)2.80794260
36Congenital primary aphakia (HP:0007707)2.80734027
37Abnormality of the labia minora (HP:0012880)2.78158839
38Renal Fanconi syndrome (HP:0001994)2.75909900
39Gait imbalance (HP:0002141)2.73865113
40Abnormality of aromatic amino acid family metabolism (HP:0004338)2.73769222
41Nephrogenic diabetes insipidus (HP:0009806)2.71566554
42Pancreatic cysts (HP:0001737)2.70657727
43Alacrima (HP:0000522)2.67120786
44Asplenia (HP:0001746)2.63957675
45Aplasia/Hypoplasia of the sacrum (HP:0008517)2.60659367
46Colon cancer (HP:0003003)2.56938703
47Morphological abnormality of the inner ear (HP:0011390)2.56245005
48Abnormality of the corticospinal tract (HP:0002492)2.52185098
49Stenosis of the external auditory canal (HP:0000402)2.52008163
50Increased serum lactate (HP:0002151)2.51494963
51Hyperglycinuria (HP:0003108)2.49551488
52Patchy hypopigmentation of hair (HP:0011365)2.48981809
53Pancreatic fibrosis (HP:0100732)2.47703746
54Abnormality of glycine metabolism (HP:0010895)2.47203952
55Abnormality of serine family amino acid metabolism (HP:0010894)2.47203952
56Prolonged neonatal jaundice (HP:0006579)2.45825925
57Aplasia/Hypoplasia of the spleen (HP:0010451)2.45294515
58Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.43995152
59Partial duplication of thumb phalanx (HP:0009944)2.43849412
60Renal cortical cysts (HP:0000803)2.43653788
61Microvesicular hepatic steatosis (HP:0001414)2.42539280
62Macrocytic anemia (HP:0001972)2.42091348
63Postnatal microcephaly (HP:0005484)2.37644725
64Progressive macrocephaly (HP:0004481)2.36900219
65True hermaphroditism (HP:0010459)2.36822153
66White forelock (HP:0002211)2.36076058
67Abnormality of midbrain morphology (HP:0002418)2.35007480
68Molar tooth sign on MRI (HP:0002419)2.35007480
69Respiratory failure (HP:0002878)2.34946949
70Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.32660664
71Cerebral edema (HP:0002181)2.30511997
72Abnormality of serum amino acid levels (HP:0003112)2.30459788
73Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.24171252
74Decreased activity of mitochondrial respiratory chain (HP:0008972)2.24171252
75Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.23618211
76Abnormality of the vitamin B12 metabolism (HP:0004341)2.21595320
77Abnormality of alanine metabolism (HP:0010916)2.18251511
78Hyperalaninemia (HP:0003348)2.18251511
79Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.18251511
80Abnormality of vitamin B metabolism (HP:0004340)2.17836993
81Reticulocytopenia (HP:0001896)2.17255537
82Abnormality of the fetal cardiovascular system (HP:0010948)2.17096351
83Abnormal umbilical cord blood vessels (HP:0011403)2.17096351
84Single umbilical artery (HP:0001195)2.17096351
85Vaginal atresia (HP:0000148)2.16602911
86Abnormal protein glycosylation (HP:0012346)2.16016965
87Abnormal glycosylation (HP:0012345)2.16016965
88Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.16016965
89Abnormal protein N-linked glycosylation (HP:0012347)2.16016965
90Genital tract atresia (HP:0001827)2.15265695
91Lethargy (HP:0001254)2.13070827
92Hypoplasia of the uterus (HP:0000013)2.11385822
93Lactic acidosis (HP:0003128)2.11029715
94Optic disc pallor (HP:0000543)2.10388469
95Abnormality of the phalanges of the 2nd finger (HP:0009541)2.09382132
96Generalized aminoaciduria (HP:0002909)2.08907333
97Nephronophthisis (HP:0000090)2.08358091
98Abnormality of the salivary glands (HP:0010286)2.06860268
99Increased intramyocellular lipid droplets (HP:0012240)2.06632482
100Decreased lacrimation (HP:0000633)2.06392677
101Premature skin wrinkling (HP:0100678)2.04821480
102Partial duplication of the phalanx of hand (HP:0009999)2.04513000
103Atrophy/Degeneration involving motor neurons (HP:0007373)2.03856019
104Type I transferrin isoform profile (HP:0003642)2.03200144
105Abnormality of aspartate family amino acid metabolism (HP:0010899)2.01923659
106CNS demyelination (HP:0007305)2.01364066
107Abnormality of the umbilical cord (HP:0010881)2.00073605
108Paraparesis (HP:0002385)1.99732512
109Hypoglycemic coma (HP:0001325)1.95742412
110Spastic gait (HP:0002064)1.95232357
111Meckel diverticulum (HP:0002245)1.94908515
112Stridor (HP:0010307)1.94544653
113Abnormality of the ileum (HP:0001549)1.91355219
114Sclerocornea (HP:0000647)1.91132795
115Abnormality of methionine metabolism (HP:0010901)1.90812506
116Cerebral hemorrhage (HP:0001342)1.90415848
117Aplasia/hypoplasia of the uterus (HP:0008684)1.89877238
118Emotional lability (HP:0000712)1.88194100
119Megaloblastic anemia (HP:0001889)1.88143364
120Neoplasm of the adrenal gland (HP:0100631)1.87675948
121Increased muscle lipid content (HP:0009058)1.86417029
122Pancytopenia (HP:0001876)1.84478835
123Steatorrhea (HP:0002570)1.82969916
124Absent septum pellucidum (HP:0001331)1.82707273
125Aplastic anemia (HP:0001915)1.81421415
126Opisthotonus (HP:0002179)1.80606963
127Poor speech (HP:0002465)1.78843612
128Exercise intolerance (HP:0003546)1.78438734
129Aplasia/Hypoplasia of the uvula (HP:0010293)1.77982787
130Delayed epiphyseal ossification (HP:0002663)1.77830692
131Abnormality of dicarboxylic acid metabolism (HP:0010995)1.77310611
132Dicarboxylic aciduria (HP:0003215)1.77310611
133Methylmalonic aciduria (HP:0012120)1.75563765
134Exertional dyspnea (HP:0002875)1.74475686
135Onion bulb formation (HP:0003383)1.74473756
136Irregular epiphyses (HP:0010582)1.74336682
137Chromosomal breakage induced by crosslinking agents (HP:0003221)1.74320559
138Oral leukoplakia (HP:0002745)1.73754483
139Abnormality of the septum pellucidum (HP:0007375)1.73734015
140Anteriorly placed anus (HP:0001545)1.73333843
141Hypobetalipoproteinemia (HP:0003563)1.72998439
142Abnormal lung lobation (HP:0002101)1.72716067
143Methylmalonic acidemia (HP:0002912)1.72481753
144Abnormality of urine glucose concentration (HP:0011016)1.72148011
145Glycosuria (HP:0003076)1.72148011
146Poor coordination (HP:0002370)1.70363794
147Adrenal hypoplasia (HP:0000835)1.69956811
148Chromsome breakage (HP:0040012)1.69927035
149Progressive microcephaly (HP:0000253)1.69168134
150Abnormality of fatty-acid metabolism (HP:0004359)1.68668039
151Reduced antithrombin III activity (HP:0001976)1.68505539
152Intestinal atresia (HP:0011100)1.64985960
153Horseshoe kidney (HP:0000085)1.64834402
154Ketoacidosis (HP:0001993)1.64507680
155Abnormality of renal resorption (HP:0011038)1.63744542
156Short tibia (HP:0005736)1.63312866
157Pendular nystagmus (HP:0012043)1.63287988

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.92172910
2VRK24.54869826
3BUB14.21814496
4OXSR13.48720285
5MAP4K23.37235916
6STK163.33174336
7PBK3.30261471
8WNK32.78021877
9LIMK12.70918378
10TESK22.67041617
11CDK192.61103479
12BCKDK2.46216637
13MET2.39828607
14MST42.32891196
15BCR2.29583580
16TSSK62.22770246
17WEE12.20485328
18NUAK12.20060797
19ZAK2.09546784
20EIF2AK12.06575867
21CSNK1G31.88009800
22TRIM281.87301179
23MAPKAPK51.84731114
24WNK41.79336910
25NEK11.74577185
26MKNK11.74035491
27PKN11.69270003
28EIF2AK31.62478694
29TXK1.61456407
30PINK11.58644721
31CSNK1A1L1.47638012
32TAF11.45150320
33CSNK1G11.44072670
34PLK41.40103100
35PASK1.37834778
36VRK11.35575228
37EPHB11.29951461
38DYRK21.28795143
39NEK61.28442703
40TLK11.27131019
41NME21.24587878
42UHMK11.23486465
43ROCK21.18084328
44MAP2K71.16856961
45TIE11.10565211
46FGFR21.10422332
47NEK21.06674241
48TNIK1.05484985
49CDC71.04914086
50PDK21.04582728
51DYRK31.02062362
52CLK11.00406431
53MAP3K40.99801228
54RPS6KB20.97099603
55GRK10.95076969
56ACVR1B0.94397400
57CSNK1G20.93075248
58PLK20.89276920
59BRSK10.87328346
60PNCK0.85451837
61ADRBK20.85305459
62KDR0.84962632
63CAMK2B0.82350979
64TESK10.82083829
65DAPK10.81287054
66BRSK20.80898085
67RPS6KA50.75174240
68MAP2K20.73988421
69MARK10.73245692
70ERBB30.72860544
71PIM20.72539045
72CSF1R0.71225970
73FRK0.68098876
74CASK0.67935150
75BMPR1B0.67338572
76SRPK10.67300893
77MAPK150.67083931
78MAPK130.66439348
79PAK10.66177255
80RPS6KA40.65905096
81CHEK20.64949197
82ARAF0.64192558
83ILK0.63712839
84INSRR0.62610287
85TRPM70.62559982
86EIF2AK20.60939693
87KIT0.60716050
88EPHB20.60041522
89AURKA0.59772142
90PRPF4B0.59049097
91MINK10.58752210
92MAP3K80.58328563
93WNK10.57296320
94CAMK2D0.56647341
95TEC0.55939285
96PRKCG0.55641525
97MKNK20.54493639
98LRRK20.54164679
99MAP3K120.53940702
100ATM0.53743919
101TGFBR10.53462836
102CSNK1A10.53084408
103FLT30.52694243
104CDK140.52214468
105CAMK2G0.52100110
106IRAK20.49808927
107CSNK1E0.48817971
108NME10.47447211
109CSNK2A20.46922428
110CDK70.45733545
111PHKG10.45491529
112PHKG20.45491529
113ICK0.44605684
114BTK0.44339025
115ITK0.43495579
116IRAK10.42843748
117PRKCI0.41497123
118CHEK10.41102949
119ABL20.39184292
120CSNK2A10.38917545
121ATR0.37070568
122PLK10.35906469
123PAK30.35586824
124TTK0.35007382
125PRKCQ0.34390333
126PLK30.34336948
127CDK11A0.34289260
128CDK150.34062540
129ALK0.33101600
130STK40.31786325
131STK38L0.31590892
132EPHA40.31444628
133PRKCE0.30951024
134BRAF0.30603592
135AURKB0.30601742
136CDK180.30588442
137CAMKK20.30199350
138SGK2230.28731586
139SGK4940.28731586
140CDK20.28722623
141FGFR10.27938171
142FGR0.27604931
143STK100.27345055
144CSNK1D0.23669581
145CDK80.23654468
146CCNB10.22011477
147ERBB40.21188708

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.59060917
2Fatty acid elongation_Homo sapiens_hsa000623.37924260
3Proteasome_Homo sapiens_hsa030503.25906270
4Protein export_Homo sapiens_hsa030603.25329811
5Steroid biosynthesis_Homo sapiens_hsa001003.21645249
6Ribosome_Homo sapiens_hsa030102.91550021
7DNA replication_Homo sapiens_hsa030302.64088070
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.57778705
9RNA polymerase_Homo sapiens_hsa030202.44541038
10Mismatch repair_Homo sapiens_hsa034302.32613402
11Oxidative phosphorylation_Homo sapiens_hsa001902.30268494
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.18764457
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.16975197
14Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.15387248
15Parkinsons disease_Homo sapiens_hsa050122.05146220
16Folate biosynthesis_Homo sapiens_hsa007902.00096245
17Sulfur metabolism_Homo sapiens_hsa009201.86684483
18Spliceosome_Homo sapiens_hsa030401.66253301
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65597141
20Glutathione metabolism_Homo sapiens_hsa004801.62633534
21Nucleotide excision repair_Homo sapiens_hsa034201.55334708
22Ether lipid metabolism_Homo sapiens_hsa005651.51782906
23Histidine metabolism_Homo sapiens_hsa003401.51638284
24Pyrimidine metabolism_Homo sapiens_hsa002401.50911919
25Vitamin B6 metabolism_Homo sapiens_hsa007501.49845975
26Homologous recombination_Homo sapiens_hsa034401.45356540
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.42503184
28Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.39074793
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.29202098
30Huntingtons disease_Homo sapiens_hsa050161.27601417
31Propanoate metabolism_Homo sapiens_hsa006401.27398667
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.27154846
33Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.27045678
34Base excision repair_Homo sapiens_hsa034101.26715603
35Alzheimers disease_Homo sapiens_hsa050101.26088135
36Basal transcription factors_Homo sapiens_hsa030221.22081479
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.21344434
38Butanoate metabolism_Homo sapiens_hsa006501.21035162
39Arginine and proline metabolism_Homo sapiens_hsa003301.18107331
40Peroxisome_Homo sapiens_hsa041461.16173912
41Linoleic acid metabolism_Homo sapiens_hsa005911.10603224
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.06752559
43Non-homologous end-joining_Homo sapiens_hsa034501.05954544
44Collecting duct acid secretion_Homo sapiens_hsa049661.05648923
45Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.05523965
46One carbon pool by folate_Homo sapiens_hsa006701.03696646
47Pentose phosphate pathway_Homo sapiens_hsa000301.02519749
48Cardiac muscle contraction_Homo sapiens_hsa042600.99242312
49Pyruvate metabolism_Homo sapiens_hsa006200.97844139
50Purine metabolism_Homo sapiens_hsa002300.97042528
51RNA transport_Homo sapiens_hsa030130.96581589
52Phototransduction_Homo sapiens_hsa047440.92085378
53Biosynthesis of amino acids_Homo sapiens_hsa012300.89957643
54Selenocompound metabolism_Homo sapiens_hsa004500.89438227
55Metabolic pathways_Homo sapiens_hsa011000.87823740
56Drug metabolism - other enzymes_Homo sapiens_hsa009830.87745410
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.86270429
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.83863785
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.83504952
60Steroid hormone biosynthesis_Homo sapiens_hsa001400.82900479
61Chemical carcinogenesis_Homo sapiens_hsa052040.81622623
62Primary bile acid biosynthesis_Homo sapiens_hsa001200.81459386
63Sphingolipid metabolism_Homo sapiens_hsa006000.81176706
64Sulfur relay system_Homo sapiens_hsa041220.80804081
65Arachidonic acid metabolism_Homo sapiens_hsa005900.80657055
66Cell cycle_Homo sapiens_hsa041100.79047466
67Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.78072458
68Carbon metabolism_Homo sapiens_hsa012000.76583147
69Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.75153840
70Regulation of autophagy_Homo sapiens_hsa041400.73251027
71RNA degradation_Homo sapiens_hsa030180.72404238
72Fatty acid metabolism_Homo sapiens_hsa012120.71422185
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68372897
74Nicotine addiction_Homo sapiens_hsa050330.65508569
75beta-Alanine metabolism_Homo sapiens_hsa004100.65063653
76Retinol metabolism_Homo sapiens_hsa008300.64313669
77Fat digestion and absorption_Homo sapiens_hsa049750.63350464
78Tyrosine metabolism_Homo sapiens_hsa003500.60783777
79Cyanoamino acid metabolism_Homo sapiens_hsa004600.60684860
80Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60600623
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54754259
82Fatty acid degradation_Homo sapiens_hsa000710.53819765
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53660490
84Fanconi anemia pathway_Homo sapiens_hsa034600.53580102
85mRNA surveillance pathway_Homo sapiens_hsa030150.52837845
86Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52020373
87Systemic lupus erythematosus_Homo sapiens_hsa053220.51762135
88Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.50584528
89Vibrio cholerae infection_Homo sapiens_hsa051100.47869420
902-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45357211
91Oocyte meiosis_Homo sapiens_hsa041140.44972934
92Nitrogen metabolism_Homo sapiens_hsa009100.44777251
93Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.44382554
94Tryptophan metabolism_Homo sapiens_hsa003800.44195008
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.43223624
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42823935
97Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.36641449
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35797477
99Maturity onset diabetes of the young_Homo sapiens_hsa049500.35283092
100Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.34454850
101N-Glycan biosynthesis_Homo sapiens_hsa005100.33999905
102Phenylalanine metabolism_Homo sapiens_hsa003600.33302774
103Epstein-Barr virus infection_Homo sapiens_hsa051690.32574907
104Tight junction_Homo sapiens_hsa045300.32203267
105Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27998430
106Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.22034614
107p53 signaling pathway_Homo sapiens_hsa041150.21415606
108Vitamin digestion and absorption_Homo sapiens_hsa049770.21235937
109Caffeine metabolism_Homo sapiens_hsa002320.20608433
110Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.15810531
111Phagosome_Homo sapiens_hsa041450.11808871
112Autoimmune thyroid disease_Homo sapiens_hsa053200.10279405
113Asthma_Homo sapiens_hsa053100.09149210

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