GLRX3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1formation of translation preinitiation complex (GO:0001731)4.95583537
2maturation of SSU-rRNA (GO:0030490)4.63135401
3ribosomal small subunit assembly (GO:0000028)4.54372044
4DNA strand elongation involved in DNA replication (GO:0006271)4.45594531
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.39348917
6nucleobase biosynthetic process (GO:0046112)4.33061388
7purine nucleobase biosynthetic process (GO:0009113)4.27205436
8ribosomal large subunit biogenesis (GO:0042273)4.25078651
9protein neddylation (GO:0045116)4.21127721
10DNA strand elongation (GO:0022616)4.20783871
11viral transcription (GO:0019083)4.19694567
12translational termination (GO:0006415)4.17681832
13proteasome assembly (GO:0043248)4.14542486
14DNA replication initiation (GO:0006270)4.14474241
15telomere maintenance via semi-conservative replication (GO:0032201)4.08664570
16DNA deamination (GO:0045006)4.07437087
17cullin deneddylation (GO:0010388)4.03798164
18establishment of protein localization to mitochondrial membrane (GO:0090151)4.01347646
19ribosome assembly (GO:0042255)3.95365615
20negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.94729459
21translational elongation (GO:0006414)3.94397935
22translational initiation (GO:0006413)3.93259632
23DNA replication-dependent nucleosome assembly (GO:0006335)3.91054677
24DNA replication-dependent nucleosome organization (GO:0034723)3.91054677
25DNA unwinding involved in DNA replication (GO:0006268)3.90781359
26chaperone-mediated protein transport (GO:0072321)3.90227293
27ribosome biogenesis (GO:0042254)3.86880946
28ribonucleoprotein complex biogenesis (GO:0022613)3.86659845
29regulation of mitochondrial translation (GO:0070129)3.85458949
30DNA replication checkpoint (GO:0000076)3.80033612
31regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.79776354
32positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.78899767
33protein deneddylation (GO:0000338)3.77929862
34anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.75698862
35establishment of viral latency (GO:0019043)3.72956883
36ribosomal small subunit biogenesis (GO:0042274)3.72108785
37mitotic metaphase plate congression (GO:0007080)3.72104368
38spliceosomal snRNP assembly (GO:0000387)3.69161904
39telomere maintenance via recombination (GO:0000722)3.66725691
40chromatin remodeling at centromere (GO:0031055)3.65514213
41CENP-A containing nucleosome assembly (GO:0034080)3.63466113
42energy coupled proton transport, down electrochemical gradient (GO:0015985)3.63210223
43ATP synthesis coupled proton transport (GO:0015986)3.63210223
44IMP biosynthetic process (GO:0006188)3.63197002
45negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.61869631
46negative regulation of ligase activity (GO:0051352)3.61869631
47SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.55853926
48nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.49817572
49folic acid-containing compound biosynthetic process (GO:0009396)3.49301047
50cotranslational protein targeting to membrane (GO:0006613)3.46395988
51mitotic recombination (GO:0006312)3.45776746
52DNA damage response, detection of DNA damage (GO:0042769)3.45136940
53DNA ligation (GO:0006266)3.44516974
54protein targeting to ER (GO:0045047)3.44488280
55DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.44233036
56rRNA processing (GO:0006364)3.42591625
57cellular protein complex disassembly (GO:0043624)3.40989957
58mitotic nuclear envelope disassembly (GO:0007077)3.39482806
59protein targeting to mitochondrion (GO:0006626)3.39410049
60signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.39043672
61intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.39043672
62protein localization to kinetochore (GO:0034501)3.38563765
63positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.38041092
64signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.36111046
65signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.36111046
66signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.36111046
67telomere maintenance via telomere lengthening (GO:0010833)3.35245627
68establishment of integrated proviral latency (GO:0075713)3.35056312
69translation (GO:0006412)3.34339160
70nucleotide-excision repair, DNA gap filling (GO:0006297)3.33835325
71DNA double-strand break processing (GO:0000729)3.32417552
72regulation of cellular amino acid metabolic process (GO:0006521)3.32223440
73signal transduction involved in DNA integrity checkpoint (GO:0072401)3.32191243
74signal transduction involved in DNA damage checkpoint (GO:0072422)3.32191243
75DNA replication-independent nucleosome organization (GO:0034724)3.31555864
76DNA replication-independent nucleosome assembly (GO:0006336)3.31555864
77rRNA metabolic process (GO:0016072)3.30493894
78viral life cycle (GO:0019058)3.29291971
79regulation of mitotic spindle checkpoint (GO:1903504)3.29005948
80regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.29005948
81signal transduction involved in cell cycle checkpoint (GO:0072395)3.28137067
82pseudouridine synthesis (GO:0001522)3.27403136
83IMP metabolic process (GO:0046040)3.26862385
84establishment of protein localization to endoplasmic reticulum (GO:0072599)3.26125973
85protein localization to endoplasmic reticulum (GO:0070972)3.26001972
86respiratory chain complex IV assembly (GO:0008535)3.24088400
87histone exchange (GO:0043486)3.22095039
88positive regulation of ligase activity (GO:0051351)3.21237564
89G1/S transition of mitotic cell cycle (GO:0000082)3.21189017
90cell cycle G1/S phase transition (GO:0044843)3.21189017
91regulation of ligase activity (GO:0051340)3.17627653
92tRNA aminoacylation for protein translation (GO:0006418)3.16955736
93metaphase plate congression (GO:0051310)3.16559123
94tRNA aminoacylation (GO:0043039)3.15670699
95amino acid activation (GO:0043038)3.15670699
96establishment of protein localization to mitochondrion (GO:0072655)3.15501078
97protein localization to mitochondrion (GO:0070585)3.15343787
98membrane disassembly (GO:0030397)3.14825559
99nuclear envelope disassembly (GO:0051081)3.14825559
100exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.13466422
101viral mRNA export from host cell nucleus (GO:0046784)3.12859314
102transcription-coupled nucleotide-excision repair (GO:0006283)3.12498873
103somatic diversification of immune receptors via somatic mutation (GO:0002566)3.12193887
104somatic hypermutation of immunoglobulin genes (GO:0016446)3.12193887
105maturation of 5.8S rRNA (GO:0000460)3.11560913
106mitochondrial respiratory chain complex assembly (GO:0033108)3.10827618
107DNA catabolic process, exonucleolytic (GO:0000738)3.10525877
108spliceosomal complex assembly (GO:0000245)3.09556009
109nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.09380109
110mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.08083539
111protein complex disassembly (GO:0043241)3.07505330
112cellular component biogenesis (GO:0044085)3.07502816
113regulation of ubiquitin-protein transferase activity (GO:0051438)3.07473881
114mitotic sister chromatid segregation (GO:0000070)3.06892050
115protein localization to chromosome, centromeric region (GO:0071459)3.06848126
116regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.05542716
117rRNA modification (GO:0000154)3.04356132
118nuclear pore organization (GO:0006999)3.03029814
119L-serine metabolic process (GO:0006563)3.02894746
120protein complex biogenesis (GO:0070271)3.01672113
121postreplication repair (GO:0006301)3.01552510
122spindle checkpoint (GO:0031577)3.01361565
123mitochondrial respiratory chain complex I assembly (GO:0032981)3.00965946
124NADH dehydrogenase complex assembly (GO:0010257)3.00965946
125mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.00965946
126negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.00872230
127negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.98901038
128negative regulation of sister chromatid segregation (GO:0033046)2.98901038
129negative regulation of mitotic sister chromatid separation (GO:2000816)2.98901038
130negative regulation of mitotic sister chromatid segregation (GO:0033048)2.98901038
131negative regulation of chromosome segregation (GO:0051985)2.98428926
132kinetochore organization (GO:0051383)2.97563207
133macromolecular complex disassembly (GO:0032984)2.97487095
134transcription elongation from RNA polymerase III promoter (GO:0006385)2.97076986
135termination of RNA polymerase III transcription (GO:0006386)2.97076986

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.98425927
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.80122682
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.06092741
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.57149604
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.37712045
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.29874021
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.27404175
8MYC_19079543_ChIP-ChIP_MESCs_Mouse3.25678808
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.23686474
10MYC_18358816_ChIP-ChIP_MESCs_Mouse3.18159077
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.16710601
12MYC_19030024_ChIP-ChIP_MESCs_Mouse3.09393208
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.02078617
14MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.99981435
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.91700954
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.73566355
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.70981508
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.62118257
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.56858571
20XRN2_22483619_ChIP-Seq_HELA_Human2.53516605
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.52037909
22VDR_23849224_ChIP-Seq_CD4+_Human2.38143954
23E2F1_18555785_ChIP-Seq_MESCs_Mouse2.31885835
24DCP1A_22483619_ChIP-Seq_HELA_Human2.25758749
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.10328217
26FOXP3_21729870_ChIP-Seq_TREG_Human2.06256604
27ELF1_17652178_ChIP-ChIP_JURKAT_Human2.05673114
28* GABP_19822575_ChIP-Seq_HepG2_Human2.02801458
29PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.01931473
30TTF2_22483619_ChIP-Seq_HELA_Human2.01778974
31THAP11_20581084_ChIP-Seq_MESCs_Mouse2.01657490
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.99575115
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.96001243
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.94800399
35AR_21909140_ChIP-Seq_LNCAP_Human1.93089023
36RBPJ_22232070_ChIP-Seq_NCS_Mouse1.89136418
37ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.87737157
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.86330021
39ZFX_18555785_ChIP-Seq_MESCs_Mouse1.80478583
40ELK1_19687146_ChIP-ChIP_HELA_Human1.78350019
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.71944059
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.70980670
43SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.70936671
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.67454573
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.65310427
46FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.63789784
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61342626
48SRF_21415370_ChIP-Seq_HL-1_Mouse1.57073352
49KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.56949868
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.53844038
51TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.50548545
52* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.50027510
53SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.48214463
54POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.47852306
55HOXB4_20404135_ChIP-ChIP_EML_Mouse1.43398169
56CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36849624
57STAT3_1855785_ChIP-Seq_MESCs_Mouse1.35824492
58* KDM5A_27292631_Chip-Seq_BREAST_Human1.31693065
59CIITA_25753668_ChIP-Seq_RAJI_Human1.31561243
60PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.31135170
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.30623674
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.29910276
63NANOG_16153702_ChIP-ChIP_HESCs_Human1.29065321
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.26972120
65SOX2_18555785_ChIP-Seq_MESCs_Mouse1.23878763
66SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.23252513
67KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.20684607
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19682549
69FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.19398923
70PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.16205159
71EWS_26573619_Chip-Seq_HEK293_Human1.16154176
72CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.15458560
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15234825
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.12248389
75ELK1_22589737_ChIP-Seq_MCF10A_Human1.10889082
76ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10516107
77TFEB_21752829_ChIP-Seq_HELA_Human1.09901320
78BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.09785679
79CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09762764
80CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.08878907
81DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.07954934
82KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06718964
83HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.05216998
84* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04770374
85SOX2_16153702_ChIP-ChIP_HESCs_Human1.03800201
86MYC_18940864_ChIP-ChIP_HL60_Human1.03670032
87POU5F1_16153702_ChIP-ChIP_HESCs_Human1.03498503
88DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03114727
89SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.03078516
90HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.00199640
91EGR1_19374776_ChIP-ChIP_THP-1_Human0.99174035
92ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.97231650
93CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.95802794
94NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.95236805
95SOX2_18692474_ChIP-Seq_MEFs_Mouse0.90940624
96NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.90365934
97CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.90323350
98NANOG_21062744_ChIP-ChIP_HESCs_Human0.90105627
99TCF3_18692474_ChIP-Seq_MEFs_Mouse0.89944422
100CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.89089536
101OCT4_18692474_ChIP-Seq_MEFs_Mouse0.88378091
102FUS_26573619_Chip-Seq_HEK293_Human0.86196845
103MYC_22102868_ChIP-Seq_BL_Human0.85443131
104CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.84845720
105SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.84175837
106NOTCH1_21737748_ChIP-Seq_TLL_Human0.81213044
107SOX17_20123909_ChIP-Seq_XEN_Mouse0.78928307
108ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.78667372
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.78450448
110TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.77824457
111ESR1_15608294_ChIP-ChIP_MCF-7_Human0.77730258
112NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.77635401
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.77301727
114FLI1_27457419_Chip-Seq_LIVER_Mouse0.73945877
115* ZNF274_21170338_ChIP-Seq_K562_Hela0.72966883
116TBX5_21415370_ChIP-Seq_HL-1_Mouse0.71134899

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.44885913
2MP0004957_abnormal_blastocyst_morpholog4.74487676
3MP0010094_abnormal_chromosome_stability4.59655257
4MP0003111_abnormal_nucleus_morphology4.07113284
5MP0003077_abnormal_cell_cycle3.88190119
6MP0008058_abnormal_DNA_repair3.63650719
7MP0008057_abnormal_DNA_replication3.06640336
8MP0008932_abnormal_embryonic_tissue3.04737990
9MP0008007_abnormal_cellular_replicative3.03657402
10MP0008877_abnormal_DNA_methylation2.74283631
11MP0003123_paternal_imprinting2.72506554
12MP0003806_abnormal_nucleotide_metabolis2.61739325
13MP0001730_embryonic_growth_arrest2.46431922
14MP0000350_abnormal_cell_proliferation2.14329537
15MP0003786_premature_aging2.12610575
16MP0010352_gastrointestinal_tract_polyps2.03487504
17MP0001529_abnormal_vocalization1.81456210
18MP0010030_abnormal_orbit_morphology1.81289812
19* MP0001697_abnormal_embryo_size1.76982242
20MP0002396_abnormal_hematopoietic_system1.76912223
21MP0001672_abnormal_embryogenesis/_devel1.71890696
22MP0005380_embryogenesis_phenotype1.71890696
23MP0002163_abnormal_gland_morphology1.69861907
24* MP0002080_prenatal_lethality1.66011780
25MP0003718_maternal_effect1.65713783
26MP0010307_abnormal_tumor_latency1.62037370
27MP0002210_abnormal_sex_determination1.58087433
28MP0003984_embryonic_growth_retardation1.56686748
29MP0002102_abnormal_ear_morphology1.56430387
30MP0002837_dystrophic_cardiac_calcinosis1.54594582
31MP0003186_abnormal_redox_activity1.53147728
32MP0002088_abnormal_embryonic_growth/wei1.52714308
33MP0003315_abnormal_perineum_morphology1.52417572
34MP0002085_abnormal_embryonic_tissue1.51686570
35MP0003567_abnormal_fetal_cardiomyocyte1.49745142
36MP0000358_abnormal_cell_content/1.47298032
37MP0006072_abnormal_retinal_apoptosis1.47082327
38MP0004133_heterotaxia1.45611095
39MP0002084_abnormal_developmental_patter1.44839109
40MP0001929_abnormal_gametogenesis1.44785934
41MP0002160_abnormal_reproductive_system1.44781824
42MP0000490_abnormal_crypts_of1.44338482
43MP0004197_abnormal_fetal_growth/weight/1.44088020
44MP0001145_abnormal_male_reproductive1.43881540
45MP0005410_abnormal_fertilization1.42803450
46MP0000313_abnormal_cell_death1.39702966
47MP0009379_abnormal_foot_pigmentation1.38564279
48MP0006036_abnormal_mitochondrial_physio1.37467884
49MP0006035_abnormal_mitochondrial_morpho1.32732310
50MP0001293_anophthalmia1.32729073
51MP0003121_genomic_imprinting1.31469509
52MP0003221_abnormal_cardiomyocyte_apopto1.27153834
53MP0002019_abnormal_tumor_incidence1.25680684
54MP0002653_abnormal_ependyma_morphology1.22876084
55MP0002086_abnormal_extraembryonic_tissu1.18399752
56MP0002697_abnormal_eye_size1.18086541
57MP0005623_abnormal_meninges_morphology1.17076383
58MP0000537_abnormal_urethra_morphology1.16572785
59MP0000750_abnormal_muscle_regeneration1.14878365
60MP0000653_abnormal_sex_gland1.13841035
61MP0005389_reproductive_system_phenotype1.11567355
62MP0000647_abnormal_sebaceous_gland1.10780783
63MP0009053_abnormal_anal_canal1.10311544
64MP0003119_abnormal_digestive_system1.10219011
65MP0003698_abnormal_male_reproductive1.08801532
66MP0002233_abnormal_nose_morphology1.07744204
67MP0004808_abnormal_hematopoietic_stem1.06526292
68MP0001188_hyperpigmentation1.04718144
69MP0002090_abnormal_vision1.01277934
70MP0003941_abnormal_skin_development1.00907536
71MP0005499_abnormal_olfactory_system1.00731895
72MP0005394_taste/olfaction_phenotype1.00731895
73MP0004233_abnormal_muscle_weight0.99730385
74MP0000579_abnormal_nail_morphology0.99054395
75MP0003890_abnormal_embryonic-extraembry0.96304045
76MP0003705_abnormal_hypodermis_morpholog0.95856994
77MP0002254_reproductive_system_inflammat0.90457886
78MP0005379_endocrine/exocrine_gland_phen0.90115857
79MP0002796_impaired_skin_barrier0.89993346
80MP0006054_spinal_hemorrhage0.89847057
81MP0005266_abnormal_metabolism0.89466361
82MP0003755_abnormal_palate_morphology0.87204003
83MP0002111_abnormal_tail_morphology0.87122400
84MP0001661_extended_life_span0.86106869
85MP0005084_abnormal_gallbladder_morpholo0.85280622
86MP0001764_abnormal_homeostasis0.84404814
87MP0002234_abnormal_pharynx_morphology0.83913132
88MP0001346_abnormal_lacrimal_gland0.83738181
89MP0002269_muscular_atrophy0.83660500
90MP0002736_abnormal_nociception_after0.81717379
91MP0005384_cellular_phenotype0.81470555
92MP0009333_abnormal_splenocyte_physiolog0.81174391
93MP0002282_abnormal_trachea_morphology0.81133216
94MP0003950_abnormal_plasma_membrane0.79869876
95MP0009672_abnormal_birth_weight0.79860762
96MP0004147_increased_porphyrin_level0.78066274
97MP0000762_abnormal_tongue_morphology0.77732410
98MP0002751_abnormal_autonomic_nervous0.77308403
99MP0001919_abnormal_reproductive_system0.77152002
100MP0002161_abnormal_fertility/fecundity0.75657546
101MP0005408_hypopigmentation0.70639782
102MP0003646_muscle_fatigue0.69903488
103MP0000858_altered_metastatic_potential0.69213746
104MP0008438_abnormal_cutaneous_collagen0.68186549
105MP0000372_irregular_coat_pigmentation0.68127673
106MP0003385_abnormal_body_wall0.68051266
107MP0002177_abnormal_outer_ear0.65682147
108MP0006292_abnormal_olfactory_placode0.64936613
109MP0001119_abnormal_female_reproductive0.64662888
110MP0000749_muscle_degeneration0.64475969
111MP0005023_abnormal_wound_healing0.64167742
112MP0009250_abnormal_appendicular_skeleto0.63589053
113MP0009697_abnormal_copulation0.63330399
114MP0000428_abnormal_craniofacial_morphol0.60582702
115MP0005621_abnormal_cell_physiology0.59419924
116MP0003937_abnormal_limbs/digits/tail_de0.59007370
117MP0002938_white_spotting0.58832081
118MP0008789_abnormal_olfactory_epithelium0.58514719
119MP0005397_hematopoietic_system_phenotyp0.58288209
120MP0001545_abnormal_hematopoietic_system0.58288209
121MP0005501_abnormal_skin_physiology0.57467906
122MP0003942_abnormal_urinary_system0.56934832
123MP0001853_heart_inflammation0.56873802
124MP0001286_abnormal_eye_development0.56649134
125MP0000703_abnormal_thymus_morphology0.55937474
126MP0000049_abnormal_middle_ear0.54978401
127MP0002114_abnormal_axial_skeleton0.54737771
128MP0001727_abnormal_embryo_implantation0.54024211
129MP0005503_abnormal_tendon_morphology0.52257685
130MP0000477_abnormal_intestine_morphology0.51875374
131MP0005275_abnormal_skin_tensile0.51255767
132MP0002132_abnormal_respiratory_system0.50646453
133MP0002722_abnormal_immune_system0.48729857

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.40659425
2Abnormality of cells of the erythroid lineage (HP:0012130)4.37943842
3Reticulocytopenia (HP:0001896)4.16851234
4Abnormal number of erythroid precursors (HP:0012131)4.01308041
5Abnormality of the anterior horn cell (HP:0006802)3.95897857
6Degeneration of anterior horn cells (HP:0002398)3.95897857
7Oral leukoplakia (HP:0002745)3.88554488
8Colon cancer (HP:0003003)3.61886365
9Selective tooth agenesis (HP:0001592)3.44291192
10Breast hypoplasia (HP:0003187)3.43375112
11Cerebral edema (HP:0002181)3.40897340
12Abnormality of glycolysis (HP:0004366)3.30876615
13Increased serum pyruvate (HP:0003542)3.30876615
14Aplastic anemia (HP:0001915)3.20197772
15Macrocytic anemia (HP:0001972)3.19341056
16Chromosomal breakage induced by crosslinking agents (HP:0003221)3.16239105
17Carpal bone hypoplasia (HP:0001498)3.09562081
18Decreased activity of mitochondrial respiratory chain (HP:0008972)3.03386702
19Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.03386702
20Cerebral hypomyelination (HP:0006808)3.02053093
21Rough bone trabeculation (HP:0100670)3.00484153
22Multiple enchondromatosis (HP:0005701)2.99947130
23Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.93997899
24Abnormality of alanine metabolism (HP:0010916)2.93997899
25Hyperalaninemia (HP:0003348)2.93997899
26Trismus (HP:0000211)2.92390077
27Pallor (HP:0000980)2.83055367
28Ependymoma (HP:0002888)2.82913449
29Increased serum lactate (HP:0002151)2.80642414
30Acute necrotizing encephalopathy (HP:0006965)2.78640056
31Increased CSF lactate (HP:0002490)2.77459683
32Renal Fanconi syndrome (HP:0001994)2.73688252
33Hepatocellular necrosis (HP:0001404)2.72560816
34Agnosia (HP:0010524)2.69855985
35Microretrognathia (HP:0000308)2.68230801
36Patellar aplasia (HP:0006443)2.67702048
37Abnormal mitochondria in muscle tissue (HP:0008316)2.67146460
38Medulloblastoma (HP:0002885)2.64216750
39Absent thumb (HP:0009777)2.60972632
40Mitochondrial inheritance (HP:0001427)2.59413531
41Microvesicular hepatic steatosis (HP:0001414)2.52362980
42Supernumerary spleens (HP:0009799)2.52354279
43Aplasia/Hypoplasia of the patella (HP:0006498)2.51127351
44Neoplasm of the pancreas (HP:0002894)2.50592089
45Atrophy/Degeneration involving motor neurons (HP:0007373)2.50216047
46Hepatic necrosis (HP:0002605)2.49779440
47Type I transferrin isoform profile (HP:0003642)2.48157534
483-Methylglutaconic aciduria (HP:0003535)2.47426014
4911 pairs of ribs (HP:0000878)2.47367169
50Respiratory failure (HP:0002878)2.38041113
51Meckel diverticulum (HP:0002245)2.37745591
52Increased intramyocellular lipid droplets (HP:0012240)2.36241514
53Leukodystrophy (HP:0002415)2.32506728
54Abnormality of the preputium (HP:0100587)2.31971221
55Abnormality of the ileum (HP:0001549)2.31727317
56Abnormality of placental membranes (HP:0011409)2.31356966
57Amniotic constriction ring (HP:0009775)2.31356966
58Abnormality of methionine metabolism (HP:0010901)2.30840664
59Abnormality of serum amino acid levels (HP:0003112)2.29106457
60Absent radius (HP:0003974)2.28423684
61Abnormality of the labia minora (HP:0012880)2.24117443
62Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.22294298
63Facial cleft (HP:0002006)2.20200832
64Exercise intolerance (HP:0003546)2.19176190
65Premature graying of hair (HP:0002216)2.18510228
66Hyperglycinemia (HP:0002154)2.18071701
67Acute encephalopathy (HP:0006846)2.17635662
68Premature ovarian failure (HP:0008209)2.16757643
69Increased hepatocellular lipid droplets (HP:0006565)2.15100077
70Aplasia/Hypoplasia of the sacrum (HP:0008517)2.14908573
71Abnormal trabecular bone morphology (HP:0100671)2.14502744
72Impulsivity (HP:0100710)2.14372414
73Optic disc pallor (HP:0000543)2.13554644
74Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.12955141
75Rhabdomyosarcoma (HP:0002859)2.11722086
76Abnormality of chromosome stability (HP:0003220)2.11523133
77Glossoptosis (HP:0000162)2.10941940
78Lactic acidosis (HP:0003128)2.10843588
79Megaloblastic anemia (HP:0001889)2.09876540
80Reduced antithrombin III activity (HP:0001976)2.09526508
81Absent forearm bone (HP:0003953)2.09305119
82Aplasia involving forearm bones (HP:0009822)2.09305119
83Postnatal microcephaly (HP:0005484)2.08742750
84Abnormality of abdominal situs (HP:0011620)2.07650078
85Abdominal situs inversus (HP:0003363)2.07650078
86Abnormal protein glycosylation (HP:0012346)2.07586087
87Abnormal glycosylation (HP:0012345)2.07586087
88Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.07586087
89Abnormal protein N-linked glycosylation (HP:0012347)2.07586087
90Pelvic girdle muscle weakness (HP:0003749)2.06717102
91Chromsome breakage (HP:0040012)2.05756996
92Muscle fiber atrophy (HP:0100295)2.04515183
93Progressive macrocephaly (HP:0004481)2.04193902
94Shoulder girdle muscle weakness (HP:0003547)2.04160886
95Abnormal spermatogenesis (HP:0008669)2.03620378
96Secondary amenorrhea (HP:0000869)2.01863447
97Progressive muscle weakness (HP:0003323)2.01434778
98Missing ribs (HP:0000921)2.01282822
99Lethargy (HP:0001254)1.99046816
100Cortical dysplasia (HP:0002539)1.98487275
101Aplasia/Hypoplasia of the uvula (HP:0010293)1.98461379
102Lipid accumulation in hepatocytes (HP:0006561)1.96335062
103Angiofibromas (HP:0010615)1.96197137
104Adenoma sebaceum (HP:0009720)1.96197137
105Horseshoe kidney (HP:0000085)1.95993953
106Respiratory difficulties (HP:0002880)1.95793815
107Exertional dyspnea (HP:0002875)1.95040649
108Sparse eyelashes (HP:0000653)1.93189941
109Neoplasm of the colon (HP:0100273)1.92970726
110Type 2 muscle fiber atrophy (HP:0003554)1.92893345
111Emotional lability (HP:0000712)1.92506465
112Hypoplasia of the capital femoral epiphysis (HP:0003090)1.91749463
113Cleft eyelid (HP:0000625)1.91420586
114Abnormal lung lobation (HP:0002101)1.90974919
115Hypoplasia of the pons (HP:0012110)1.90907409
116Pancytopenia (HP:0001876)1.90767902
117Duodenal stenosis (HP:0100867)1.90137936
118Small intestinal stenosis (HP:0012848)1.90137936
119CNS demyelination (HP:0007305)1.90086495
120Calcaneovalgus deformity (HP:0001848)1.88528186
121Tongue fasciculations (HP:0001308)1.88234403
122Nephroblastoma (Wilms tumor) (HP:0002667)1.88010456
123Embryonal renal neoplasm (HP:0011794)1.87900112
124Stenosis of the external auditory canal (HP:0000402)1.87369986
125Cellular immunodeficiency (HP:0005374)1.87199913
126Abnormality of the duodenum (HP:0002246)1.86840151
127Tracheoesophageal fistula (HP:0002575)1.86788653
128Triphalangeal thumb (HP:0001199)1.85121511
129Spastic diplegia (HP:0001264)1.82935273
130Abnormal number of incisors (HP:0011064)1.82777378
131Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.81703416
132Abnormality of aspartate family amino acid metabolism (HP:0010899)1.79762798
133Abnormalities of placenta or umbilical cord (HP:0001194)1.79034243
134Hypoplastic pelvis (HP:0008839)1.78233403
135Increased muscle lipid content (HP:0009058)1.71821008
136X-linked dominant inheritance (HP:0001423)1.71691534
137Sloping forehead (HP:0000340)1.70922581
138Increased nuchal translucency (HP:0010880)1.67292938

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.69187750
2WEE14.22063383
3EIF2AK13.99798508
4CDC73.31175481
5STK162.84831217
6NEK12.81788749
7NME22.81155440
8VRK22.81063974
9TRIM282.68894889
10PDK32.67832714
11PDK42.67832714
12SRPK12.38181023
13EIF2AK32.31346064
14TSSK62.30439214
15BCR2.21639681
16TESK22.18496721
17TESK12.17821516
18NEK22.00307952
19ACVR1B1.98749923
20PLK41.89018964
21BRSK21.86018725
22TTK1.84153586
23TLK11.82052989
24PLK11.79094603
25DYRK31.72326593
26RPS6KB21.61753988
27PDK21.60044051
28VRK11.57227054
29EPHA21.51297287
30MKNK11.49154273
31PLK31.48490603
32PASK1.47034044
33SCYL21.41020661
34AURKB1.40390839
35MAP3K121.35117426
36AURKA1.33297657
37LIMK11.31489561
38NME11.29240094
39BCKDK1.28422654
40ATR1.28349829
41MAPKAPK31.27908254
42ZAK1.26944863
43CDK71.24340502
44PAK41.21848183
45TGFBR11.21242437
46PIM21.16793013
47CHEK21.15900429
48BRSK11.14953198
49RPS6KA41.14575915
50NUAK11.13650876
51CCNB11.13519203
52TAF11.10786491
53WNK31.03946112
54MAP4K20.96447535
55MAP3K80.96034161
56CSNK1G30.94608542
57MKNK20.91920388
58CHEK10.86268378
59BMPR1B0.85884580
60ERBB40.85018130
61FLT30.84755503
62CSNK1G10.84717882
63KDR0.82435336
64PBK0.78332350
65LATS20.75816851
66STK38L0.75444321
67CDK40.74324082
68CSNK2A20.73344778
69CSNK1G20.72818627
70CSNK1A1L0.71498654
71CSNK2A10.71418945
72MAP3K110.71099177
73PAK10.70637831
74EEF2K0.70454110
75EIF2AK20.69133533
76MAP2K70.67095853
77PNCK0.64231141
78PKN20.64102862
79STK30.62975785
80LRRK20.62265852
81DYRK20.61557554
82BRAF0.61012224
83PLK20.60561972
84SIK30.60233774
85ILK0.58281073
86TNIK0.57517270
87PRKCI0.56025096
88CDK20.54807643
89ATM0.53729758
90NEK90.51561993
91TAOK20.50509672
92CDK80.49723986
93ERBB30.49477634
94MAP3K40.48552279
95STK100.47676370
96PIM10.46813523
97CLK10.43568813
98MYLK0.42197313
99STK240.41193367
100STK40.40031896
101MINK10.39030787
102CDK10.38893060
103MAP2K60.37684898
104CDK180.36320146
105AKT20.34798998
106DAPK10.34753547
107CDK60.32697628
108MAP2K30.32457127
109LMTK20.31726463
110CSNK1E0.30246578
111STK390.29228626
112MAP3K50.28754847
113FGFR10.27324982
114DAPK30.26397197
115CDK140.25240070
116DYRK1B0.25237848
117CDK190.22683856
118MST40.21103192
119PAK20.20657539
120RPS6KA50.20407870
121ABL20.19980493
122MAP3K100.19842704
123YES10.18893856
124PIK3CG0.17715429
125CDK11A0.17709197
126MELK0.16707321
127ALK0.16656232

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.51447296
2Proteasome_Homo sapiens_hsa030504.49367621
3Ribosome_Homo sapiens_hsa030104.05228957
4Mismatch repair_Homo sapiens_hsa034303.97363259
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.61256166
6RNA polymerase_Homo sapiens_hsa030203.24113377
7Spliceosome_Homo sapiens_hsa030403.13498216
8RNA transport_Homo sapiens_hsa030133.07558820
9Nucleotide excision repair_Homo sapiens_hsa034202.79946436
10Base excision repair_Homo sapiens_hsa034102.69049057
11Homologous recombination_Homo sapiens_hsa034402.61150706
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.60727474
13Pyrimidine metabolism_Homo sapiens_hsa002402.53207757
14One carbon pool by folate_Homo sapiens_hsa006702.39756867
15Cell cycle_Homo sapiens_hsa041102.34322079
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.86519918
17Fanconi anemia pathway_Homo sapiens_hsa034601.85101888
18Basal transcription factors_Homo sapiens_hsa030221.81245662
19RNA degradation_Homo sapiens_hsa030181.63249567
20Steroid biosynthesis_Homo sapiens_hsa001001.62113727
21Non-homologous end-joining_Homo sapiens_hsa034501.57390025
22p53 signaling pathway_Homo sapiens_hsa041151.55235179
23Parkinsons disease_Homo sapiens_hsa050121.53268655
24Fatty acid elongation_Homo sapiens_hsa000621.47914274
25mRNA surveillance pathway_Homo sapiens_hsa030151.43863079
26Huntingtons disease_Homo sapiens_hsa050161.42956787
27Oxidative phosphorylation_Homo sapiens_hsa001901.41769897
28Purine metabolism_Homo sapiens_hsa002301.39651316
29Biosynthesis of amino acids_Homo sapiens_hsa012301.30673428
30Carbon metabolism_Homo sapiens_hsa012001.26708503
31Pentose phosphate pathway_Homo sapiens_hsa000301.21055483
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.20790221
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.17981649
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.14154276
35Epstein-Barr virus infection_Homo sapiens_hsa051691.13274359
36Systemic lupus erythematosus_Homo sapiens_hsa053221.04615120
37Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.03588210
38Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.02704866
39Folate biosynthesis_Homo sapiens_hsa007901.00247449
40Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.99706830
41Sulfur metabolism_Homo sapiens_hsa009200.98117348
42Oocyte meiosis_Homo sapiens_hsa041140.97265291
43Pyruvate metabolism_Homo sapiens_hsa006200.95710606
44Protein export_Homo sapiens_hsa030600.89832418
45Selenocompound metabolism_Homo sapiens_hsa004500.87983208
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.81104792
47Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.76514799
48Glutathione metabolism_Homo sapiens_hsa004800.76391615
49Drug metabolism - other enzymes_Homo sapiens_hsa009830.75723936
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.74953408
51Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74927682
52Vitamin B6 metabolism_Homo sapiens_hsa007500.73557554
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.73362785
54Cyanoamino acid metabolism_Homo sapiens_hsa004600.72530249
55Viral carcinogenesis_Homo sapiens_hsa052030.71465424
56Alzheimers disease_Homo sapiens_hsa050100.70643125
57Sulfur relay system_Homo sapiens_hsa041220.68653260
58Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.67656669
59Fructose and mannose metabolism_Homo sapiens_hsa000510.66576620
60Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.65603350
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61672099
62Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.61372336
63Antigen processing and presentation_Homo sapiens_hsa046120.55435264
64Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.55283986
65Legionellosis_Homo sapiens_hsa051340.55044924
66Propanoate metabolism_Homo sapiens_hsa006400.54728926
67Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52953428
68Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51391249
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51180498
70HTLV-I infection_Homo sapiens_hsa051660.46600815
71Metabolic pathways_Homo sapiens_hsa011000.45898560
72Thyroid cancer_Homo sapiens_hsa052160.45675348
73Herpes simplex infection_Homo sapiens_hsa051680.45320467
74Peroxisome_Homo sapiens_hsa041460.39947563
75Fatty acid metabolism_Homo sapiens_hsa012120.39701349
76N-Glycan biosynthesis_Homo sapiens_hsa005100.35914021
77Butanoate metabolism_Homo sapiens_hsa006500.35855344
78Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.34659618
79Renin-angiotensin system_Homo sapiens_hsa046140.33344304
80Alcoholism_Homo sapiens_hsa050340.33158606
81Hippo signaling pathway_Homo sapiens_hsa043900.32984392
82beta-Alanine metabolism_Homo sapiens_hsa004100.32327760
83Cardiac muscle contraction_Homo sapiens_hsa042600.32157969
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.30553283
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.28456017
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.26930015
87HIF-1 signaling pathway_Homo sapiens_hsa040660.26780118
88Phototransduction_Homo sapiens_hsa047440.26629281
89Shigellosis_Homo sapiens_hsa051310.26480901
90Regulation of autophagy_Homo sapiens_hsa041400.26240868
91TGF-beta signaling pathway_Homo sapiens_hsa043500.25877542
92Fatty acid degradation_Homo sapiens_hsa000710.25186222
93Tryptophan metabolism_Homo sapiens_hsa003800.25144535
94Galactose metabolism_Homo sapiens_hsa000520.24179259
95Collecting duct acid secretion_Homo sapiens_hsa049660.22943490
96Caffeine metabolism_Homo sapiens_hsa002320.22899077
97Small cell lung cancer_Homo sapiens_hsa052220.21398021
98Basal cell carcinoma_Homo sapiens_hsa052170.20331691
99Bladder cancer_Homo sapiens_hsa052190.20204977
100Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20005533
101Arginine and proline metabolism_Homo sapiens_hsa003300.18198269
102MicroRNAs in cancer_Homo sapiens_hsa052060.15729362
103Apoptosis_Homo sapiens_hsa042100.15406378
104Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.15167479
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.15020841
106Hedgehog signaling pathway_Homo sapiens_hsa043400.13743297
107Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.13492554
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.12562050
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.11713764
110Primary bile acid biosynthesis_Homo sapiens_hsa001200.11009824
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.10941519
112Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.08575239
113Arachidonic acid metabolism_Homo sapiens_hsa005900.08573528
114Retinol metabolism_Homo sapiens_hsa008300.08337523
115Tyrosine metabolism_Homo sapiens_hsa003500.08312328
116Viral myocarditis_Homo sapiens_hsa054160.08203941
117Colorectal cancer_Homo sapiens_hsa052100.08114547
118Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.07157601
119Wnt signaling pathway_Homo sapiens_hsa043100.06542894
120Melanoma_Homo sapiens_hsa052180.04236522
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.03258688
122Pathways in cancer_Homo sapiens_hsa052000.02993209
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.00516073
124Vibrio cholerae infection_Homo sapiens_hsa05110-0.0023618
125Tight junction_Homo sapiens_hsa04530-0.0010505
126Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280-0.0009997

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