GLRX3P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein neddylation (GO:0045116)4.91062200
2signal peptide processing (GO:0006465)4.41303251
3neuron fate determination (GO:0048664)4.32724434
4DNA double-strand break processing (GO:0000729)4.18417172
5preassembly of GPI anchor in ER membrane (GO:0016254)4.14219492
6establishment of protein localization to mitochondrial membrane (GO:0090151)4.06877294
7maturation of SSU-rRNA (GO:0030490)4.04281879
8rRNA methylation (GO:0031167)3.93029011
9mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.87712760
10mitochondrial respiratory chain complex I assembly (GO:0032981)3.87712760
11NADH dehydrogenase complex assembly (GO:0010257)3.87712760
12tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.86038337
13RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.86038337
14centriole replication (GO:0007099)3.75539513
15behavioral response to nicotine (GO:0035095)3.74639981
16somite development (GO:0061053)3.69122224
17telencephalon development (GO:0021537)3.62895153
18cell proliferation in forebrain (GO:0021846)3.59227262
19rRNA modification (GO:0000154)3.55916421
20chaperone-mediated protein transport (GO:0072321)3.53083562
21tongue development (GO:0043586)3.50579465
22negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.47697105
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.44702282
24protein complex biogenesis (GO:0070271)3.39586186
25peptidyl-histidine modification (GO:0018202)3.37529381
26neuronal stem cell maintenance (GO:0097150)3.32282425
27protein polyglutamylation (GO:0018095)3.27425555
28radial glial cell differentiation (GO:0060019)3.24086922
29respiratory chain complex IV assembly (GO:0008535)3.22820333
30energy coupled proton transport, down electrochemical gradient (GO:0015985)3.21841866
31ATP synthesis coupled proton transport (GO:0015986)3.21841866
32DNA catabolic process, exonucleolytic (GO:0000738)3.18445992
33mitochondrial respiratory chain complex assembly (GO:0033108)3.17235207
34activated T cell proliferation (GO:0050798)3.16562292
35GPI anchor metabolic process (GO:0006505)3.16073336
36negative regulation of mast cell activation (GO:0033004)3.12469260
37nephron epithelium morphogenesis (GO:0072088)3.11578491
38nephron tubule morphogenesis (GO:0072078)3.11578491
39GPI anchor biosynthetic process (GO:0006506)3.11524792
40postreplication repair (GO:0006301)3.10568286
41neuronal action potential propagation (GO:0019227)3.09249675
42positive regulation of mitochondrial fission (GO:0090141)3.03119731
43DNA strand renaturation (GO:0000733)3.01675335
44regulation of hexokinase activity (GO:1903299)3.01352909
45regulation of glucokinase activity (GO:0033131)3.01352909
46proteasome assembly (GO:0043248)2.99984100
47spermatid nucleus differentiation (GO:0007289)2.98256371
48ovulation cycle (GO:0042698)2.93679443
49C-terminal protein amino acid modification (GO:0018410)2.91211835
50nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.88321686
51C-terminal protein lipidation (GO:0006501)2.88257582
52neurotransmitter catabolic process (GO:0042135)2.84651242
53DNA deamination (GO:0045006)2.84377531
54intracellular protein transmembrane import (GO:0044743)2.79455341
55exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.78957863
56water-soluble vitamin biosynthetic process (GO:0042364)2.78327754
57otic vesicle formation (GO:0030916)2.76625162
58viral transcription (GO:0019083)2.75993590
59postsynaptic membrane organization (GO:0001941)2.75663922
60translational termination (GO:0006415)2.73173733
61regulation of feeding behavior (GO:0060259)2.72174035
62negative regulation of oligodendrocyte differentiation (GO:0048715)2.72146187
63mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.71476297
64protein localization to cilium (GO:0061512)2.70587832
65regulation of cytokine production involved in inflammatory response (GO:1900015)2.69930117
66myoblast migration (GO:0051451)2.68952235
67glyoxylate metabolic process (GO:0046487)2.67843030
68SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.66994018
69kynurenine metabolic process (GO:0070189)2.65928667
70pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.65763261
71detection of temperature stimulus involved in sensory perception (GO:0050961)2.64996136
72detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.64996136
73positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.63864248
74detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)2.63498200
75cotranslational protein targeting to membrane (GO:0006613)2.63185041
76respiratory electron transport chain (GO:0022904)2.62727954
77electron transport chain (GO:0022900)2.61106740
78protein targeting to ER (GO:0045047)2.60786592
79regulation of glycogen (starch) synthase activity (GO:2000465)2.59270033
80centriole assembly (GO:0098534)2.56362067
81cardiovascular system development (GO:0072358)2.55642770
82amine catabolic process (GO:0009310)2.55550780
83cellular biogenic amine catabolic process (GO:0042402)2.55550780
84nucleotide transmembrane transport (GO:1901679)2.55058263
85cellular ketone body metabolic process (GO:0046950)2.54656519
86IMP biosynthetic process (GO:0006188)2.54471358
87purine-containing compound salvage (GO:0043101)2.54245825
88ribosomal small subunit assembly (GO:0000028)2.53908170
89protein localization to synapse (GO:0035418)2.53626183
90negative regulation of epidermis development (GO:0045683)2.52353086
91protein K11-linked deubiquitination (GO:0035871)2.51208713
92nucleobase biosynthetic process (GO:0046112)2.50840112
93tRNA processing (GO:0008033)2.50717807
94negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.50654451
95cullin deneddylation (GO:0010388)2.49763292
96lactate metabolic process (GO:0006089)2.49644685
97purine nucleobase biosynthetic process (GO:0009113)2.49150834
98cytochrome complex assembly (GO:0017004)2.48797494
99protein localization to endoplasmic reticulum (GO:0070972)2.47481627
100positive regulation of response to tumor cell (GO:0002836)2.47052528

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.16420305
2ZNF274_21170338_ChIP-Seq_K562_Hela3.47853344
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.38317778
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.36297578
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.16648166
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.96492904
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.89495667
8VDR_22108803_ChIP-Seq_LS180_Human2.69401534
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.32163491
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.18590029
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.11546772
12CTBP1_25329375_ChIP-Seq_LNCAP_Human2.05118362
13POU5F1_16153702_ChIP-ChIP_HESCs_Human2.03751336
14ER_23166858_ChIP-Seq_MCF-7_Human2.02798486
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.01918274
16POU3F2_20337985_ChIP-ChIP_501MEL_Human2.01317533
17EWS_26573619_Chip-Seq_HEK293_Human2.01292273
18GBX2_23144817_ChIP-Seq_PC3_Human1.95383651
19VDR_23849224_ChIP-Seq_CD4+_Human1.93856199
20CBX2_27304074_Chip-Seq_ESCs_Mouse1.93123390
21IGF1R_20145208_ChIP-Seq_DFB_Human1.91949414
22ETS1_20019798_ChIP-Seq_JURKAT_Human1.90727033
23ELK1_19687146_ChIP-ChIP_HELA_Human1.90522166
24P300_19829295_ChIP-Seq_ESCs_Human1.86796773
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.86659161
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.84482307
27CTBP2_25329375_ChIP-Seq_LNCAP_Human1.77774682
28FUS_26573619_Chip-Seq_HEK293_Human1.76277300
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.64890465
30EZH2_22144423_ChIP-Seq_EOC_Human1.58844101
31JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.58093733
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.56830977
33UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.55509821
34TAF15_26573619_Chip-Seq_HEK293_Human1.55058196
35PCGF2_27294783_Chip-Seq_ESCs_Mouse1.54376840
36MYC_18940864_ChIP-ChIP_HL60_Human1.52061465
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.45739989
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.43891285
39MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.42916554
40NOTCH1_21737748_ChIP-Seq_TLL_Human1.40944838
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.40708511
42NANOG_19829295_ChIP-Seq_ESCs_Human1.36640023
43SOX2_19829295_ChIP-Seq_ESCs_Human1.36640023
44RNF2_27304074_Chip-Seq_NSC_Mouse1.35003854
45EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.32038196
46FOXP3_21729870_ChIP-Seq_TREG_Human1.30745064
47SRF_21415370_ChIP-Seq_HL-1_Mouse1.29995936
48GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28323810
49NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.26358476
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.24689613
51CREB1_15753290_ChIP-ChIP_HEK293T_Human1.24280463
52IRF1_19129219_ChIP-ChIP_H3396_Human1.23671694
53EZH2_27304074_Chip-Seq_ESCs_Mouse1.21863939
54TP53_22573176_ChIP-Seq_HFKS_Human1.19581857
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.19279476
56NFE2_27457419_Chip-Seq_LIVER_Mouse1.18792403
57REST_21632747_ChIP-Seq_MESCs_Mouse1.18616973
58KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18438693
59BCAT_22108803_ChIP-Seq_LS180_Human1.17592930
60NCOR_22424771_ChIP-Seq_293T_Human1.17092361
61FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.15569502
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.14184420
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13625268
64ETV2_25802403_ChIP-Seq_MESCs_Mouse1.10927557
65FOXA1_27270436_Chip-Seq_PROSTATE_Human1.10785729
66FOXA1_25329375_ChIP-Seq_VCAP_Human1.10785729
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10175038
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10175038
69IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.09123453
70CBP_20019798_ChIP-Seq_JUKART_Human1.09123453
71SOX2_16153702_ChIP-ChIP_HESCs_Human1.07792323
72FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07377611
73AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07009830
74EZH2_27294783_Chip-Seq_NPCs_Mouse1.06983674
75OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06381235
76SALL1_21062744_ChIP-ChIP_HESCs_Human1.05132969
77SMAD4_21741376_ChIP-Seq_EPCs_Human1.04977495
78PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04077807
79ELF1_17652178_ChIP-ChIP_JURKAT_Human1.04023757
80SMAD4_21799915_ChIP-Seq_A2780_Human1.04011566
81HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.03175011
82CRX_20693478_ChIP-Seq_RETINA_Mouse1.02759486
83P53_22387025_ChIP-Seq_ESCs_Mouse1.01655129
84ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.01239718
85AR_25329375_ChIP-Seq_VCAP_Human1.01172692
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99442777
87CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99117068
88SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97485635
89GABP_19822575_ChIP-Seq_HepG2_Human0.96243962
90ELK1_22589737_ChIP-Seq_MCF10A_Human0.94729681
91PADI4_21655091_ChIP-ChIP_MCF-7_Human0.93584800
92PIAS1_25552417_ChIP-Seq_VCAP_Human0.90922607
93KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.90345801
94SMAD3_21741376_ChIP-Seq_ESCs_Human0.90218403
95TAL1_26923725_Chip-Seq_HPCs_Mouse0.90104396
96NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.90080793
97FOXH1_21741376_ChIP-Seq_EPCs_Human0.89889704
98TTF2_22483619_ChIP-Seq_HELA_Human0.89828133
99AUTS2_25519132_ChIP-Seq_293T-REX_Human0.89006998
100JARID2_20064375_ChIP-Seq_MESCs_Mouse0.88704019

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.18469608
2MP0006292_abnormal_olfactory_placode2.95098399
3MP0003136_yellow_coat_color2.88200838
4MP0009379_abnormal_foot_pigmentation2.81320817
5MP0002102_abnormal_ear_morphology2.56340269
6MP0002163_abnormal_gland_morphology2.53905666
7MP0005423_abnormal_somatic_nervous2.24029357
8MP0002653_abnormal_ependyma_morphology2.18681180
9MP0002837_dystrophic_cardiac_calcinosis2.17840702
10MP0004142_abnormal_muscle_tone2.16665215
11MP0005379_endocrine/exocrine_gland_phen2.09974664
12MP0008875_abnormal_xenobiotic_pharmacok1.97700341
13MP0002277_abnormal_respiratory_mucosa1.97448837
14MP0003646_muscle_fatigue1.94765449
15MP0004145_abnormal_muscle_electrophysio1.92839543
16MP0003787_abnormal_imprinting1.87501454
17MP0003011_delayed_dark_adaptation1.85009812
18MP0002736_abnormal_nociception_after1.80822592
19MP0005551_abnormal_eye_electrophysiolog1.72421322
20MP0006072_abnormal_retinal_apoptosis1.72332662
21MP0001968_abnormal_touch/_nociception1.71074018
22MP0005253_abnormal_eye_physiology1.70228267
23MP0005084_abnormal_gallbladder_morpholo1.64436873
24MP0003122_maternal_imprinting1.58454882
25MP0001529_abnormal_vocalization1.57402550
26MP0008872_abnormal_physiological_respon1.53791458
27MP0002928_abnormal_bile_duct1.47552294
28MP0004215_abnormal_myocardial_fiber1.42332561
29MP0000569_abnormal_digit_pigmentation1.42233391
30MP0000383_abnormal_hair_follicle1.40664476
31MP0008877_abnormal_DNA_methylation1.40477297
32MP0001501_abnormal_sleep_pattern1.40206651
33MP0001986_abnormal_taste_sensitivity1.38710815
34MP0006036_abnormal_mitochondrial_physio1.36005628
35MP0002095_abnormal_skin_pigmentation1.35380216
36MP0002272_abnormal_nervous_system1.30265586
37MP0009745_abnormal_behavioral_response1.29677660
38MP0006276_abnormal_autonomic_nervous1.26631406
39MP0001346_abnormal_lacrimal_gland1.23516422
40MP0000427_abnormal_hair_cycle1.23036698
41MP0002234_abnormal_pharynx_morphology1.22384803
42MP0005671_abnormal_response_to1.20362470
43MP0005195_abnormal_posterior_eye1.20242801
44MP0003121_genomic_imprinting1.18179267
45MP0000647_abnormal_sebaceous_gland1.18068382
46MP0000372_irregular_coat_pigmentation1.17192829
47MP0000631_abnormal_neuroendocrine_gland1.14740147
48MP0002138_abnormal_hepatobiliary_system1.14472071
49MP0002822_catalepsy1.14051914
50MP0009053_abnormal_anal_canal1.13374697
51MP0002733_abnormal_thermal_nociception1.12314327
52MP0001970_abnormal_pain_threshold1.10319259
53MP0001286_abnormal_eye_development1.10021666
54MP0002160_abnormal_reproductive_system1.09077045
55MP0001905_abnormal_dopamine_level1.06481722
56MP0000026_abnormal_inner_ear1.04656004
57MP0002067_abnormal_sensory_capabilities1.04336165
58MP0003806_abnormal_nucleotide_metabolis1.03496961
59MP0008789_abnormal_olfactory_epithelium1.03376041
60MP0002876_abnormal_thyroid_physiology1.01419798
61MP0002751_abnormal_autonomic_nervous0.99280700
62MP0000778_abnormal_nervous_system0.99065693
63MP0002282_abnormal_trachea_morphology0.97890236
64MP0001485_abnormal_pinna_reflex0.97563434
65MP0005499_abnormal_olfactory_system0.96645558
66MP0005394_taste/olfaction_phenotype0.96645558
67MP0001293_anophthalmia0.95000854
68MP0009250_abnormal_appendicular_skeleto0.94596551
69MP0002938_white_spotting0.94443526
70MP0001486_abnormal_startle_reflex0.93161026
71MP0002752_abnormal_somatic_nervous0.92910484
72MP0000955_abnormal_spinal_cord0.92539916
73MP0008995_early_reproductive_senescence0.92408086
74MP0003137_abnormal_impulse_conducting0.90956566
75MP0002735_abnormal_chemical_nociception0.89742702
76MP0001963_abnormal_hearing_physiology0.89202537
77MP0002734_abnormal_mechanical_nocicepti0.88901233
78MP0002572_abnormal_emotion/affect_behav0.87601706
79MP0008058_abnormal_DNA_repair0.87400830
80MP0009765_abnormal_xenobiotic_induced0.85467447
81MP0000049_abnormal_middle_ear0.84786077
82MP0004742_abnormal_vestibular_system0.84146663
83MP0000685_abnormal_immune_system0.83822433
84MP0002184_abnormal_innervation0.81708438
85MP0005391_vision/eye_phenotype0.79788030
86MP0001348_abnormal_lacrimal_gland0.78172985
87MP0002557_abnormal_social/conspecific_i0.76554871
88MP0004084_abnormal_cardiac_muscle0.76360295
89MP0002909_abnormal_adrenal_gland0.75754779
90MP0005389_reproductive_system_phenotype0.75638354
91MP0002210_abnormal_sex_determination0.75432234
92MP0004133_heterotaxia0.75104595
93MP0000613_abnormal_salivary_gland0.73712677
94MP0000467_abnormal_esophagus_morphology0.72496173
95MP0002063_abnormal_learning/memory/cond0.72447056
96MP0001790_abnormal_immune_system0.69610049
97MP0005387_immune_system_phenotype0.69610049
98MP0002109_abnormal_limb_morphology0.69585500
99MP0003718_maternal_effect0.67997685
100MP0003890_abnormal_embryonic-extraembry0.67529522

Predicted human phenotypes

RankGene SetZ-score
1Molar tooth sign on MRI (HP:0002419)4.35807162
2Abnormality of midbrain morphology (HP:0002418)4.35807162
3Mitochondrial inheritance (HP:0001427)3.54822155
4Septo-optic dysplasia (HP:0100842)3.50136428
5Hepatocellular necrosis (HP:0001404)3.47089413
6Medial flaring of the eyebrow (HP:0010747)3.46948884
7Acute necrotizing encephalopathy (HP:0006965)3.44214738
8Submucous cleft hard palate (HP:0000176)3.39084013
9Pancreatic cysts (HP:0001737)3.34045356
10Increased hepatocellular lipid droplets (HP:0006565)3.32496470
11Median cleft lip (HP:0000161)3.27482982
12Pendular nystagmus (HP:0012043)3.26600679
13Increased CSF lactate (HP:0002490)3.12893653
14Acute encephalopathy (HP:0006846)3.11470305
15Hepatic necrosis (HP:0002605)3.05343080
16Lipid accumulation in hepatocytes (HP:0006561)3.04268214
17True hermaphroditism (HP:0010459)3.02578265
18Nephronophthisis (HP:0000090)2.95236152
19Progressive macrocephaly (HP:0004481)2.93317547
20Abnormal mitochondria in muscle tissue (HP:0008316)2.90397861
21Aplasia/Hypoplasia of the uvula (HP:0010293)2.82515510
22Abnormal number of incisors (HP:0011064)2.82317552
233-Methylglutaconic aciduria (HP:0003535)2.77727660
24Gait imbalance (HP:0002141)2.70305051
25Pancreatic fibrosis (HP:0100732)2.63300256
26Nephrogenic diabetes insipidus (HP:0009806)2.62975124
27Congenital primary aphakia (HP:0007707)2.58397912
28Renal Fanconi syndrome (HP:0001994)2.52877190
29Optic disc pallor (HP:0000543)2.52648926
30Abnormality of the nasal septum (HP:0000419)2.52178468
31Adrenal hypoplasia (HP:0000835)2.51081183
32Type 2 muscle fiber atrophy (HP:0003554)2.49611904
33Rib fusion (HP:0000902)2.45862034
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.44002070
35Renal cortical cysts (HP:0000803)2.42838904
36Hyperalaninemia (HP:0003348)2.42167324
37Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.42167324
38Abnormality of alanine metabolism (HP:0010916)2.42167324
39Retinal dysplasia (HP:0007973)2.41552485
40Abnormality of the renal collecting system (HP:0004742)2.40564865
41Duplicated collecting system (HP:0000081)2.38666880
42Absent thumb (HP:0009777)2.38096674
43Abnormality of the renal cortex (HP:0011035)2.37376158
44Hypomagnesemia (HP:0002917)2.35993444
45Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.35343905
46Microretrognathia (HP:0000308)2.34559444
47Optic nerve hypoplasia (HP:0000609)2.33855105
48Exertional dyspnea (HP:0002875)2.32941932
49Postaxial foot polydactyly (HP:0001830)2.31276884
50Congenital, generalized hypertrichosis (HP:0004540)2.27646695
51Abnormality of the renal medulla (HP:0100957)2.24603075
52Methylmalonic acidemia (HP:0002912)2.23825687
53Absent septum pellucidum (HP:0001331)2.21746887
54Abnormality of renal resorption (HP:0011038)2.20148041
55Alveolar cell carcinoma (HP:0006519)2.18654427
56Type II lissencephaly (HP:0007260)2.16825417
57Inability to walk (HP:0002540)2.16730682
58Respiratory difficulties (HP:0002880)2.14747890
59Vaginal atresia (HP:0000148)2.13601319
60Mesomelia (HP:0003027)2.12749820
61Congenital stationary night blindness (HP:0007642)2.11819062
62Cerebral edema (HP:0002181)2.10823936
63Poor coordination (HP:0002370)2.10709942
64Muscle fiber atrophy (HP:0100295)2.09708217
65Porencephaly (HP:0002132)2.09597518
66Reticulocytopenia (HP:0001896)2.09366743
67Absent/shortened dynein arms (HP:0200106)2.09105882
68Dynein arm defect of respiratory motile cilia (HP:0012255)2.09105882
69Genital tract atresia (HP:0001827)2.04113080
70Congenital hepatic fibrosis (HP:0002612)2.03906411
71Adactyly (HP:0009776)1.97055526
72Meckel diverticulum (HP:0002245)1.96257214
73Increased serum lactate (HP:0002151)1.95335048
74Postaxial hand polydactyly (HP:0001162)1.94606027
75Abolished electroretinogram (ERG) (HP:0000550)1.93636431
76Lactic acidosis (HP:0003128)1.93454971
77Abnormality of the ileum (HP:0001549)1.90981270
78Increased intramyocellular lipid droplets (HP:0012240)1.90544243
79Sclerocornea (HP:0000647)1.90214988
80Abnormality of the septum pellucidum (HP:0007375)1.88892620
81Abnormality of the incisor (HP:0000676)1.87945548
82Lissencephaly (HP:0001339)1.86712115
83Neoplasm of the tracheobronchial system (HP:0100552)1.85939740
84Severe visual impairment (HP:0001141)1.85650762
85Aplasia/Hypoplasia involving the musculature (HP:0001460)1.85298217
86Intestinal atresia (HP:0011100)1.82978830
87Hypothermia (HP:0002045)1.79254060
88Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.78910113
89Methylmalonic aciduria (HP:0012120)1.78185504
90Limb dystonia (HP:0002451)1.78087872
91Abnormality of the lower motor neuron (HP:0002366)1.77664550
92Large for gestational age (HP:0001520)1.76808797
93Chronic hepatic failure (HP:0100626)1.76531000
94Leukodystrophy (HP:0002415)1.72615866
95Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.72191511
96Cystic liver disease (HP:0006706)1.71748414
97Progressive inability to walk (HP:0002505)1.70814531
98Abnormal biliary tract physiology (HP:0012439)1.69336753
99Bile duct proliferation (HP:0001408)1.69336753
100Bony spicule pigmentary retinopathy (HP:0007737)1.68326180

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.10216982
2TRIM283.21243001
3BCKDK3.19012743
4MAP4K23.04281052
5WNK32.86789621
6NEK12.60600391
7FRK2.25847450
8MAP3K42.15861687
9BCR2.04553383
10TSSK61.98863585
11EPHA41.98833058
12VRK21.95963086
13MAPK151.85546325
14MAPK131.81615643
15GRK11.76895712
16EPHB21.63580554
17ERBB41.58200656
18VRK11.53509866
19WNK41.52699394
20ADRBK21.51968282
21NUAK11.46913505
22MST41.45165399
23TXK1.44749320
24SRPK11.41760273
25SGK21.37255588
26NME11.36983923
27MAP2K71.36605074
28PHKG21.32338557
29PHKG11.32338557
30MARK11.31548063
31TLK11.30343510
32MUSK1.24451246
33PINK11.23417555
34IKBKE1.19208654
35PAK31.13589636
36PRKCG1.11222232
37PKN11.10967839
38PLK41.09279337
39OBSCN1.08917535
40BMPR1B1.05087395
41CASK1.04640313
42ACVR1B0.99545059
43DYRK20.98908299
44PIK3CA0.96162609
45SGK4940.93531066
46SGK2230.93531066
47IKBKB0.90652426
48PASK0.88953473
49ERBB30.85034060
50ZAK0.83097344
51TAF10.82677818
52TGFBR10.82045702
53SGK30.78231105
54EIF2AK10.76199769
55PLK30.73300972
56PRKCE0.70936228
57STK390.67599989
58AKT30.67272581
59MAP3K120.67210715
60TEC0.67149333
61CCNB10.66946559
62MKNK20.64286993
63ATR0.63865396
64DAPK20.63417761
65PLK20.63055989
66SIK30.62956519
67EIF2AK20.62518507
68MKNK10.59398037
69ADRBK10.59033835
70CSNK1G20.58778315
71STK40.56371502
72TNIK0.53530674
73PRKCH0.53057195
74PRKCD0.51591899
75OXSR10.48717782
76CHUK0.47349789
77CAMK2A0.47238167
78CAMK40.46342764
79PRKACA0.44883775
80NTRK20.44553638
81ERBB20.44165431
82CSNK1G30.43506921
83CAMKK20.43424866
84INSRR0.42728952
85STK110.42178865
86RPS6KA40.41684240
87PRKAA20.41189259
88CSNK1A10.39563821
89SGK10.39331661
90CSNK1G10.38448477
91DAPK10.38446484
92KSR10.37750074
93CSNK2A20.34992331
94PRKG10.34810930
95CSNK2A10.34364979
96TIE10.33141013
97PRKCB0.31001165
98STK30.30873788
99MAP2K40.29285506
100PRKCQ0.28317030

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.34100181
2Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.31530780
3Protein export_Homo sapiens_hsa030603.30034171
4Sulfur relay system_Homo sapiens_hsa041223.23821703
5Ribosome_Homo sapiens_hsa030103.05445283
6Proteasome_Homo sapiens_hsa030502.77846973
7Parkinsons disease_Homo sapiens_hsa050122.72729344
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.58514924
9Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.18069521
10Collecting duct acid secretion_Homo sapiens_hsa049662.02681521
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.00856172
12Butanoate metabolism_Homo sapiens_hsa006501.98315913
13Propanoate metabolism_Homo sapiens_hsa006401.91389631
14Fanconi anemia pathway_Homo sapiens_hsa034601.91027979
15Huntingtons disease_Homo sapiens_hsa050161.88423549
16Basal transcription factors_Homo sapiens_hsa030221.83280913
17Caffeine metabolism_Homo sapiens_hsa002321.79669984
18Homologous recombination_Homo sapiens_hsa034401.75509729
19RNA polymerase_Homo sapiens_hsa030201.73223217
20Nitrogen metabolism_Homo sapiens_hsa009101.68260597
21Alzheimers disease_Homo sapiens_hsa050101.62126999
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.59656937
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.58285381
24Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.54364454
25Cardiac muscle contraction_Homo sapiens_hsa042601.54010928
26Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.50303385
27Mismatch repair_Homo sapiens_hsa034301.50072588
28RNA degradation_Homo sapiens_hsa030181.49853015
29Nicotine addiction_Homo sapiens_hsa050331.46135415
30Taste transduction_Homo sapiens_hsa047421.46056868
31Asthma_Homo sapiens_hsa053101.35930029
32Phototransduction_Homo sapiens_hsa047441.32101127
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.22732280
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.22400960
35Tryptophan metabolism_Homo sapiens_hsa003801.20646460
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.14935054
37Pyruvate metabolism_Homo sapiens_hsa006201.10611894
38Nucleotide excision repair_Homo sapiens_hsa034201.09525916
39Type I diabetes mellitus_Homo sapiens_hsa049401.01046498
40Ether lipid metabolism_Homo sapiens_hsa005651.00506225
41Cyanoamino acid metabolism_Homo sapiens_hsa004600.99978897
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98624010
43Peroxisome_Homo sapiens_hsa041460.95705514
44Linoleic acid metabolism_Homo sapiens_hsa005910.94099936
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91671602
46Non-homologous end-joining_Homo sapiens_hsa034500.91065143
47Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.88915302
48One carbon pool by folate_Homo sapiens_hsa006700.86028687
49alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.83388506
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.82318334
51Intestinal immune network for IgA production_Homo sapiens_hsa046720.76966139
52Folate biosynthesis_Homo sapiens_hsa007900.76200155
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76007114
54Purine metabolism_Homo sapiens_hsa002300.74647322
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70888903
56Pyrimidine metabolism_Homo sapiens_hsa002400.70694632
57Autoimmune thyroid disease_Homo sapiens_hsa053200.67977913
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.63436467
59Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63099586
60Metabolic pathways_Homo sapiens_hsa011000.62616421
61Retinol metabolism_Homo sapiens_hsa008300.62568158
62beta-Alanine metabolism_Homo sapiens_hsa004100.61956249
63Primary bile acid biosynthesis_Homo sapiens_hsa001200.61588905
64Spliceosome_Homo sapiens_hsa030400.61278941
65Allograft rejection_Homo sapiens_hsa053300.60253992
66Circadian rhythm_Homo sapiens_hsa047100.59363342
67Olfactory transduction_Homo sapiens_hsa047400.58859682
68GABAergic synapse_Homo sapiens_hsa047270.58103959
69SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54621671
70Morphine addiction_Homo sapiens_hsa050320.53813558
71RNA transport_Homo sapiens_hsa030130.53092467
72Chemical carcinogenesis_Homo sapiens_hsa052040.53004299
73Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52983665
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.52665479
75Fatty acid degradation_Homo sapiens_hsa000710.51526165
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50960755
77Basal cell carcinoma_Homo sapiens_hsa052170.50881959
78Hedgehog signaling pathway_Homo sapiens_hsa043400.50665163
79Base excision repair_Homo sapiens_hsa034100.49595570
80Primary immunodeficiency_Homo sapiens_hsa053400.48015110
81Vitamin digestion and absorption_Homo sapiens_hsa049770.44696951
82Regulation of autophagy_Homo sapiens_hsa041400.43506842
83Dorso-ventral axis formation_Homo sapiens_hsa043200.42962978
84Cysteine and methionine metabolism_Homo sapiens_hsa002700.42607988
85Arginine and proline metabolism_Homo sapiens_hsa003300.41828078
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.36100335
87mRNA surveillance pathway_Homo sapiens_hsa030150.36048142
88Synaptic vesicle cycle_Homo sapiens_hsa047210.35317916
89Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.33728077
90Rheumatoid arthritis_Homo sapiens_hsa053230.33136092
91Graft-versus-host disease_Homo sapiens_hsa053320.32982146
92Starch and sucrose metabolism_Homo sapiens_hsa005000.30504978
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28995130
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.27772809
95Glycerolipid metabolism_Homo sapiens_hsa005610.27655425
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.26319639
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.23348393
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.22980453
99Insulin secretion_Homo sapiens_hsa049110.22930367
100Oocyte meiosis_Homo sapiens_hsa041140.22828119

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »