

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 4.91062200 |
| 2 | signal peptide processing (GO:0006465) | 4.41303251 |
| 3 | neuron fate determination (GO:0048664) | 4.32724434 |
| 4 | DNA double-strand break processing (GO:0000729) | 4.18417172 |
| 5 | preassembly of GPI anchor in ER membrane (GO:0016254) | 4.14219492 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.06877294 |
| 7 | maturation of SSU-rRNA (GO:0030490) | 4.04281879 |
| 8 | rRNA methylation (GO:0031167) | 3.93029011 |
| 9 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.87712760 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.87712760 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 3.87712760 |
| 12 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.86038337 |
| 13 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.86038337 |
| 14 | centriole replication (GO:0007099) | 3.75539513 |
| 15 | behavioral response to nicotine (GO:0035095) | 3.74639981 |
| 16 | somite development (GO:0061053) | 3.69122224 |
| 17 | telencephalon development (GO:0021537) | 3.62895153 |
| 18 | cell proliferation in forebrain (GO:0021846) | 3.59227262 |
| 19 | rRNA modification (GO:0000154) | 3.55916421 |
| 20 | chaperone-mediated protein transport (GO:0072321) | 3.53083562 |
| 21 | tongue development (GO:0043586) | 3.50579465 |
| 22 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.47697105 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.44702282 |
| 24 | protein complex biogenesis (GO:0070271) | 3.39586186 |
| 25 | peptidyl-histidine modification (GO:0018202) | 3.37529381 |
| 26 | neuronal stem cell maintenance (GO:0097150) | 3.32282425 |
| 27 | protein polyglutamylation (GO:0018095) | 3.27425555 |
| 28 | radial glial cell differentiation (GO:0060019) | 3.24086922 |
| 29 | respiratory chain complex IV assembly (GO:0008535) | 3.22820333 |
| 30 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.21841866 |
| 31 | ATP synthesis coupled proton transport (GO:0015986) | 3.21841866 |
| 32 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.18445992 |
| 33 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.17235207 |
| 34 | activated T cell proliferation (GO:0050798) | 3.16562292 |
| 35 | GPI anchor metabolic process (GO:0006505) | 3.16073336 |
| 36 | negative regulation of mast cell activation (GO:0033004) | 3.12469260 |
| 37 | nephron epithelium morphogenesis (GO:0072088) | 3.11578491 |
| 38 | nephron tubule morphogenesis (GO:0072078) | 3.11578491 |
| 39 | GPI anchor biosynthetic process (GO:0006506) | 3.11524792 |
| 40 | postreplication repair (GO:0006301) | 3.10568286 |
| 41 | neuronal action potential propagation (GO:0019227) | 3.09249675 |
| 42 | positive regulation of mitochondrial fission (GO:0090141) | 3.03119731 |
| 43 | DNA strand renaturation (GO:0000733) | 3.01675335 |
| 44 | regulation of hexokinase activity (GO:1903299) | 3.01352909 |
| 45 | regulation of glucokinase activity (GO:0033131) | 3.01352909 |
| 46 | proteasome assembly (GO:0043248) | 2.99984100 |
| 47 | spermatid nucleus differentiation (GO:0007289) | 2.98256371 |
| 48 | ovulation cycle (GO:0042698) | 2.93679443 |
| 49 | C-terminal protein amino acid modification (GO:0018410) | 2.91211835 |
| 50 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.88321686 |
| 51 | C-terminal protein lipidation (GO:0006501) | 2.88257582 |
| 52 | neurotransmitter catabolic process (GO:0042135) | 2.84651242 |
| 53 | DNA deamination (GO:0045006) | 2.84377531 |
| 54 | intracellular protein transmembrane import (GO:0044743) | 2.79455341 |
| 55 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.78957863 |
| 56 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.78327754 |
| 57 | otic vesicle formation (GO:0030916) | 2.76625162 |
| 58 | viral transcription (GO:0019083) | 2.75993590 |
| 59 | postsynaptic membrane organization (GO:0001941) | 2.75663922 |
| 60 | translational termination (GO:0006415) | 2.73173733 |
| 61 | regulation of feeding behavior (GO:0060259) | 2.72174035 |
| 62 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.72146187 |
| 63 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.71476297 |
| 64 | protein localization to cilium (GO:0061512) | 2.70587832 |
| 65 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 2.69930117 |
| 66 | myoblast migration (GO:0051451) | 2.68952235 |
| 67 | glyoxylate metabolic process (GO:0046487) | 2.67843030 |
| 68 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.66994018 |
| 69 | kynurenine metabolic process (GO:0070189) | 2.65928667 |
| 70 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.65763261 |
| 71 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 2.64996136 |
| 72 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 2.64996136 |
| 73 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.63864248 |
| 74 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 2.63498200 |
| 75 | cotranslational protein targeting to membrane (GO:0006613) | 2.63185041 |
| 76 | respiratory electron transport chain (GO:0022904) | 2.62727954 |
| 77 | electron transport chain (GO:0022900) | 2.61106740 |
| 78 | protein targeting to ER (GO:0045047) | 2.60786592 |
| 79 | regulation of glycogen (starch) synthase activity (GO:2000465) | 2.59270033 |
| 80 | centriole assembly (GO:0098534) | 2.56362067 |
| 81 | cardiovascular system development (GO:0072358) | 2.55642770 |
| 82 | amine catabolic process (GO:0009310) | 2.55550780 |
| 83 | cellular biogenic amine catabolic process (GO:0042402) | 2.55550780 |
| 84 | nucleotide transmembrane transport (GO:1901679) | 2.55058263 |
| 85 | cellular ketone body metabolic process (GO:0046950) | 2.54656519 |
| 86 | IMP biosynthetic process (GO:0006188) | 2.54471358 |
| 87 | purine-containing compound salvage (GO:0043101) | 2.54245825 |
| 88 | ribosomal small subunit assembly (GO:0000028) | 2.53908170 |
| 89 | protein localization to synapse (GO:0035418) | 2.53626183 |
| 90 | negative regulation of epidermis development (GO:0045683) | 2.52353086 |
| 91 | protein K11-linked deubiquitination (GO:0035871) | 2.51208713 |
| 92 | nucleobase biosynthetic process (GO:0046112) | 2.50840112 |
| 93 | tRNA processing (GO:0008033) | 2.50717807 |
| 94 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 2.50654451 |
| 95 | cullin deneddylation (GO:0010388) | 2.49763292 |
| 96 | lactate metabolic process (GO:0006089) | 2.49644685 |
| 97 | purine nucleobase biosynthetic process (GO:0009113) | 2.49150834 |
| 98 | cytochrome complex assembly (GO:0017004) | 2.48797494 |
| 99 | protein localization to endoplasmic reticulum (GO:0070972) | 2.47481627 |
| 100 | positive regulation of response to tumor cell (GO:0002836) | 2.47052528 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.16420305 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.47853344 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.38317778 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.36297578 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.16648166 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.96492904 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.89495667 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.69401534 |
| 9 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.32163491 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.18590029 |
| 11 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.11546772 |
| 12 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.05118362 |
| 13 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.03751336 |
| 14 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.02798486 |
| 15 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.01918274 |
| 16 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.01317533 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 2.01292273 |
| 18 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.95383651 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.93856199 |
| 20 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.93123390 |
| 21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.91949414 |
| 22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.90727033 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.90522166 |
| 24 | P300_19829295_ChIP-Seq_ESCs_Human | 1.86796773 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.86659161 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.84482307 |
| 27 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.77774682 |
| 28 | FUS_26573619_Chip-Seq_HEK293_Human | 1.76277300 |
| 29 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.64890465 |
| 30 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.58844101 |
| 31 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.58093733 |
| 32 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.56830977 |
| 33 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.55509821 |
| 34 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.55058196 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.54376840 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.52061465 |
| 37 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.45739989 |
| 38 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.43891285 |
| 39 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.42916554 |
| 40 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.40944838 |
| 41 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.40708511 |
| 42 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.36640023 |
| 43 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.36640023 |
| 44 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.35003854 |
| 45 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.32038196 |
| 46 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.30745064 |
| 47 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.29995936 |
| 48 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28323810 |
| 49 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.26358476 |
| 50 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.24689613 |
| 51 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.24280463 |
| 52 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.23671694 |
| 53 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.21863939 |
| 54 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.19581857 |
| 55 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.19279476 |
| 56 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.18792403 |
| 57 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.18616973 |
| 58 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.18438693 |
| 59 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.17592930 |
| 60 | NCOR_22424771_ChIP-Seq_293T_Human | 1.17092361 |
| 61 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.15569502 |
| 62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.14184420 |
| 63 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.13625268 |
| 64 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.10927557 |
| 65 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.10785729 |
| 66 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.10785729 |
| 67 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10175038 |
| 68 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.10175038 |
| 69 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.09123453 |
| 70 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.09123453 |
| 71 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.07792323 |
| 72 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.07377611 |
| 73 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.07009830 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.06983674 |
| 75 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06381235 |
| 76 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.05132969 |
| 77 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.04977495 |
| 78 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.04077807 |
| 79 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.04023757 |
| 80 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.04011566 |
| 81 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.03175011 |
| 82 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02759486 |
| 83 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.01655129 |
| 84 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.01239718 |
| 85 | AR_25329375_ChIP-Seq_VCAP_Human | 1.01172692 |
| 86 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.99442777 |
| 87 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99117068 |
| 88 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97485635 |
| 89 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.96243962 |
| 90 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.94729681 |
| 91 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.93584800 |
| 92 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.90922607 |
| 93 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.90345801 |
| 94 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.90218403 |
| 95 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.90104396 |
| 96 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.90080793 |
| 97 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.89889704 |
| 98 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.89828133 |
| 99 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89006998 |
| 100 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.88704019 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 3.18469608 |
| 2 | MP0006292_abnormal_olfactory_placode | 2.95098399 |
| 3 | MP0003136_yellow_coat_color | 2.88200838 |
| 4 | MP0009379_abnormal_foot_pigmentation | 2.81320817 |
| 5 | MP0002102_abnormal_ear_morphology | 2.56340269 |
| 6 | MP0002163_abnormal_gland_morphology | 2.53905666 |
| 7 | MP0005423_abnormal_somatic_nervous | 2.24029357 |
| 8 | MP0002653_abnormal_ependyma_morphology | 2.18681180 |
| 9 | MP0002837_dystrophic_cardiac_calcinosis | 2.17840702 |
| 10 | MP0004142_abnormal_muscle_tone | 2.16665215 |
| 11 | MP0005379_endocrine/exocrine_gland_phen | 2.09974664 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 1.97700341 |
| 13 | MP0002277_abnormal_respiratory_mucosa | 1.97448837 |
| 14 | MP0003646_muscle_fatigue | 1.94765449 |
| 15 | MP0004145_abnormal_muscle_electrophysio | 1.92839543 |
| 16 | MP0003787_abnormal_imprinting | 1.87501454 |
| 17 | MP0003011_delayed_dark_adaptation | 1.85009812 |
| 18 | MP0002736_abnormal_nociception_after | 1.80822592 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.72421322 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.72332662 |
| 21 | MP0001968_abnormal_touch/_nociception | 1.71074018 |
| 22 | MP0005253_abnormal_eye_physiology | 1.70228267 |
| 23 | MP0005084_abnormal_gallbladder_morpholo | 1.64436873 |
| 24 | MP0003122_maternal_imprinting | 1.58454882 |
| 25 | MP0001529_abnormal_vocalization | 1.57402550 |
| 26 | MP0008872_abnormal_physiological_respon | 1.53791458 |
| 27 | MP0002928_abnormal_bile_duct | 1.47552294 |
| 28 | MP0004215_abnormal_myocardial_fiber | 1.42332561 |
| 29 | MP0000569_abnormal_digit_pigmentation | 1.42233391 |
| 30 | MP0000383_abnormal_hair_follicle | 1.40664476 |
| 31 | MP0008877_abnormal_DNA_methylation | 1.40477297 |
| 32 | MP0001501_abnormal_sleep_pattern | 1.40206651 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.38710815 |
| 34 | MP0006036_abnormal_mitochondrial_physio | 1.36005628 |
| 35 | MP0002095_abnormal_skin_pigmentation | 1.35380216 |
| 36 | MP0002272_abnormal_nervous_system | 1.30265586 |
| 37 | MP0009745_abnormal_behavioral_response | 1.29677660 |
| 38 | MP0006276_abnormal_autonomic_nervous | 1.26631406 |
| 39 | MP0001346_abnormal_lacrimal_gland | 1.23516422 |
| 40 | MP0000427_abnormal_hair_cycle | 1.23036698 |
| 41 | MP0002234_abnormal_pharynx_morphology | 1.22384803 |
| 42 | MP0005671_abnormal_response_to | 1.20362470 |
| 43 | MP0005195_abnormal_posterior_eye | 1.20242801 |
| 44 | MP0003121_genomic_imprinting | 1.18179267 |
| 45 | MP0000647_abnormal_sebaceous_gland | 1.18068382 |
| 46 | MP0000372_irregular_coat_pigmentation | 1.17192829 |
| 47 | MP0000631_abnormal_neuroendocrine_gland | 1.14740147 |
| 48 | MP0002138_abnormal_hepatobiliary_system | 1.14472071 |
| 49 | MP0002822_catalepsy | 1.14051914 |
| 50 | MP0009053_abnormal_anal_canal | 1.13374697 |
| 51 | MP0002733_abnormal_thermal_nociception | 1.12314327 |
| 52 | MP0001970_abnormal_pain_threshold | 1.10319259 |
| 53 | MP0001286_abnormal_eye_development | 1.10021666 |
| 54 | MP0002160_abnormal_reproductive_system | 1.09077045 |
| 55 | MP0001905_abnormal_dopamine_level | 1.06481722 |
| 56 | MP0000026_abnormal_inner_ear | 1.04656004 |
| 57 | MP0002067_abnormal_sensory_capabilities | 1.04336165 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.03496961 |
| 59 | MP0008789_abnormal_olfactory_epithelium | 1.03376041 |
| 60 | MP0002876_abnormal_thyroid_physiology | 1.01419798 |
| 61 | MP0002751_abnormal_autonomic_nervous | 0.99280700 |
| 62 | MP0000778_abnormal_nervous_system | 0.99065693 |
| 63 | MP0002282_abnormal_trachea_morphology | 0.97890236 |
| 64 | MP0001485_abnormal_pinna_reflex | 0.97563434 |
| 65 | MP0005499_abnormal_olfactory_system | 0.96645558 |
| 66 | MP0005394_taste/olfaction_phenotype | 0.96645558 |
| 67 | MP0001293_anophthalmia | 0.95000854 |
| 68 | MP0009250_abnormal_appendicular_skeleto | 0.94596551 |
| 69 | MP0002938_white_spotting | 0.94443526 |
| 70 | MP0001486_abnormal_startle_reflex | 0.93161026 |
| 71 | MP0002752_abnormal_somatic_nervous | 0.92910484 |
| 72 | MP0000955_abnormal_spinal_cord | 0.92539916 |
| 73 | MP0008995_early_reproductive_senescence | 0.92408086 |
| 74 | MP0003137_abnormal_impulse_conducting | 0.90956566 |
| 75 | MP0002735_abnormal_chemical_nociception | 0.89742702 |
| 76 | MP0001963_abnormal_hearing_physiology | 0.89202537 |
| 77 | MP0002734_abnormal_mechanical_nocicepti | 0.88901233 |
| 78 | MP0002572_abnormal_emotion/affect_behav | 0.87601706 |
| 79 | MP0008058_abnormal_DNA_repair | 0.87400830 |
| 80 | MP0009765_abnormal_xenobiotic_induced | 0.85467447 |
| 81 | MP0000049_abnormal_middle_ear | 0.84786077 |
| 82 | MP0004742_abnormal_vestibular_system | 0.84146663 |
| 83 | MP0000685_abnormal_immune_system | 0.83822433 |
| 84 | MP0002184_abnormal_innervation | 0.81708438 |
| 85 | MP0005391_vision/eye_phenotype | 0.79788030 |
| 86 | MP0001348_abnormal_lacrimal_gland | 0.78172985 |
| 87 | MP0002557_abnormal_social/conspecific_i | 0.76554871 |
| 88 | MP0004084_abnormal_cardiac_muscle | 0.76360295 |
| 89 | MP0002909_abnormal_adrenal_gland | 0.75754779 |
| 90 | MP0005389_reproductive_system_phenotype | 0.75638354 |
| 91 | MP0002210_abnormal_sex_determination | 0.75432234 |
| 92 | MP0004133_heterotaxia | 0.75104595 |
| 93 | MP0000613_abnormal_salivary_gland | 0.73712677 |
| 94 | MP0000467_abnormal_esophagus_morphology | 0.72496173 |
| 95 | MP0002063_abnormal_learning/memory/cond | 0.72447056 |
| 96 | MP0001790_abnormal_immune_system | 0.69610049 |
| 97 | MP0005387_immune_system_phenotype | 0.69610049 |
| 98 | MP0002109_abnormal_limb_morphology | 0.69585500 |
| 99 | MP0003718_maternal_effect | 0.67997685 |
| 100 | MP0003890_abnormal_embryonic-extraembry | 0.67529522 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Molar tooth sign on MRI (HP:0002419) | 4.35807162 |
| 2 | Abnormality of midbrain morphology (HP:0002418) | 4.35807162 |
| 3 | Mitochondrial inheritance (HP:0001427) | 3.54822155 |
| 4 | Septo-optic dysplasia (HP:0100842) | 3.50136428 |
| 5 | Hepatocellular necrosis (HP:0001404) | 3.47089413 |
| 6 | Medial flaring of the eyebrow (HP:0010747) | 3.46948884 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.44214738 |
| 8 | Submucous cleft hard palate (HP:0000176) | 3.39084013 |
| 9 | Pancreatic cysts (HP:0001737) | 3.34045356 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.32496470 |
| 11 | Median cleft lip (HP:0000161) | 3.27482982 |
| 12 | Pendular nystagmus (HP:0012043) | 3.26600679 |
| 13 | Increased CSF lactate (HP:0002490) | 3.12893653 |
| 14 | Acute encephalopathy (HP:0006846) | 3.11470305 |
| 15 | Hepatic necrosis (HP:0002605) | 3.05343080 |
| 16 | Lipid accumulation in hepatocytes (HP:0006561) | 3.04268214 |
| 17 | True hermaphroditism (HP:0010459) | 3.02578265 |
| 18 | Nephronophthisis (HP:0000090) | 2.95236152 |
| 19 | Progressive macrocephaly (HP:0004481) | 2.93317547 |
| 20 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.90397861 |
| 21 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.82515510 |
| 22 | Abnormal number of incisors (HP:0011064) | 2.82317552 |
| 23 | 3-Methylglutaconic aciduria (HP:0003535) | 2.77727660 |
| 24 | Gait imbalance (HP:0002141) | 2.70305051 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.63300256 |
| 26 | Nephrogenic diabetes insipidus (HP:0009806) | 2.62975124 |
| 27 | Congenital primary aphakia (HP:0007707) | 2.58397912 |
| 28 | Renal Fanconi syndrome (HP:0001994) | 2.52877190 |
| 29 | Optic disc pallor (HP:0000543) | 2.52648926 |
| 30 | Abnormality of the nasal septum (HP:0000419) | 2.52178468 |
| 31 | Adrenal hypoplasia (HP:0000835) | 2.51081183 |
| 32 | Type 2 muscle fiber atrophy (HP:0003554) | 2.49611904 |
| 33 | Rib fusion (HP:0000902) | 2.45862034 |
| 34 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.44002070 |
| 35 | Renal cortical cysts (HP:0000803) | 2.42838904 |
| 36 | Hyperalaninemia (HP:0003348) | 2.42167324 |
| 37 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.42167324 |
| 38 | Abnormality of alanine metabolism (HP:0010916) | 2.42167324 |
| 39 | Retinal dysplasia (HP:0007973) | 2.41552485 |
| 40 | Abnormality of the renal collecting system (HP:0004742) | 2.40564865 |
| 41 | Duplicated collecting system (HP:0000081) | 2.38666880 |
| 42 | Absent thumb (HP:0009777) | 2.38096674 |
| 43 | Abnormality of the renal cortex (HP:0011035) | 2.37376158 |
| 44 | Hypomagnesemia (HP:0002917) | 2.35993444 |
| 45 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.35343905 |
| 46 | Microretrognathia (HP:0000308) | 2.34559444 |
| 47 | Optic nerve hypoplasia (HP:0000609) | 2.33855105 |
| 48 | Exertional dyspnea (HP:0002875) | 2.32941932 |
| 49 | Postaxial foot polydactyly (HP:0001830) | 2.31276884 |
| 50 | Congenital, generalized hypertrichosis (HP:0004540) | 2.27646695 |
| 51 | Abnormality of the renal medulla (HP:0100957) | 2.24603075 |
| 52 | Methylmalonic acidemia (HP:0002912) | 2.23825687 |
| 53 | Absent septum pellucidum (HP:0001331) | 2.21746887 |
| 54 | Abnormality of renal resorption (HP:0011038) | 2.20148041 |
| 55 | Alveolar cell carcinoma (HP:0006519) | 2.18654427 |
| 56 | Type II lissencephaly (HP:0007260) | 2.16825417 |
| 57 | Inability to walk (HP:0002540) | 2.16730682 |
| 58 | Respiratory difficulties (HP:0002880) | 2.14747890 |
| 59 | Vaginal atresia (HP:0000148) | 2.13601319 |
| 60 | Mesomelia (HP:0003027) | 2.12749820 |
| 61 | Congenital stationary night blindness (HP:0007642) | 2.11819062 |
| 62 | Cerebral edema (HP:0002181) | 2.10823936 |
| 63 | Poor coordination (HP:0002370) | 2.10709942 |
| 64 | Muscle fiber atrophy (HP:0100295) | 2.09708217 |
| 65 | Porencephaly (HP:0002132) | 2.09597518 |
| 66 | Reticulocytopenia (HP:0001896) | 2.09366743 |
| 67 | Absent/shortened dynein arms (HP:0200106) | 2.09105882 |
| 68 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.09105882 |
| 69 | Genital tract atresia (HP:0001827) | 2.04113080 |
| 70 | Congenital hepatic fibrosis (HP:0002612) | 2.03906411 |
| 71 | Adactyly (HP:0009776) | 1.97055526 |
| 72 | Meckel diverticulum (HP:0002245) | 1.96257214 |
| 73 | Increased serum lactate (HP:0002151) | 1.95335048 |
| 74 | Postaxial hand polydactyly (HP:0001162) | 1.94606027 |
| 75 | Abolished electroretinogram (ERG) (HP:0000550) | 1.93636431 |
| 76 | Lactic acidosis (HP:0003128) | 1.93454971 |
| 77 | Abnormality of the ileum (HP:0001549) | 1.90981270 |
| 78 | Increased intramyocellular lipid droplets (HP:0012240) | 1.90544243 |
| 79 | Sclerocornea (HP:0000647) | 1.90214988 |
| 80 | Abnormality of the septum pellucidum (HP:0007375) | 1.88892620 |
| 81 | Abnormality of the incisor (HP:0000676) | 1.87945548 |
| 82 | Lissencephaly (HP:0001339) | 1.86712115 |
| 83 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.85939740 |
| 84 | Severe visual impairment (HP:0001141) | 1.85650762 |
| 85 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.85298217 |
| 86 | Intestinal atresia (HP:0011100) | 1.82978830 |
| 87 | Hypothermia (HP:0002045) | 1.79254060 |
| 88 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.78910113 |
| 89 | Methylmalonic aciduria (HP:0012120) | 1.78185504 |
| 90 | Limb dystonia (HP:0002451) | 1.78087872 |
| 91 | Abnormality of the lower motor neuron (HP:0002366) | 1.77664550 |
| 92 | Large for gestational age (HP:0001520) | 1.76808797 |
| 93 | Chronic hepatic failure (HP:0100626) | 1.76531000 |
| 94 | Leukodystrophy (HP:0002415) | 1.72615866 |
| 95 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.72191511 |
| 96 | Cystic liver disease (HP:0006706) | 1.71748414 |
| 97 | Progressive inability to walk (HP:0002505) | 1.70814531 |
| 98 | Abnormal biliary tract physiology (HP:0012439) | 1.69336753 |
| 99 | Bile duct proliferation (HP:0001408) | 1.69336753 |
| 100 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.68326180 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 4.10216982 |
| 2 | TRIM28 | 3.21243001 |
| 3 | BCKDK | 3.19012743 |
| 4 | MAP4K2 | 3.04281052 |
| 5 | WNK3 | 2.86789621 |
| 6 | NEK1 | 2.60600391 |
| 7 | FRK | 2.25847450 |
| 8 | MAP3K4 | 2.15861687 |
| 9 | BCR | 2.04553383 |
| 10 | TSSK6 | 1.98863585 |
| 11 | EPHA4 | 1.98833058 |
| 12 | VRK2 | 1.95963086 |
| 13 | MAPK15 | 1.85546325 |
| 14 | MAPK13 | 1.81615643 |
| 15 | GRK1 | 1.76895712 |
| 16 | EPHB2 | 1.63580554 |
| 17 | ERBB4 | 1.58200656 |
| 18 | VRK1 | 1.53509866 |
| 19 | WNK4 | 1.52699394 |
| 20 | ADRBK2 | 1.51968282 |
| 21 | NUAK1 | 1.46913505 |
| 22 | MST4 | 1.45165399 |
| 23 | TXK | 1.44749320 |
| 24 | SRPK1 | 1.41760273 |
| 25 | SGK2 | 1.37255588 |
| 26 | NME1 | 1.36983923 |
| 27 | MAP2K7 | 1.36605074 |
| 28 | PHKG2 | 1.32338557 |
| 29 | PHKG1 | 1.32338557 |
| 30 | MARK1 | 1.31548063 |
| 31 | TLK1 | 1.30343510 |
| 32 | MUSK | 1.24451246 |
| 33 | PINK1 | 1.23417555 |
| 34 | IKBKE | 1.19208654 |
| 35 | PAK3 | 1.13589636 |
| 36 | PRKCG | 1.11222232 |
| 37 | PKN1 | 1.10967839 |
| 38 | PLK4 | 1.09279337 |
| 39 | OBSCN | 1.08917535 |
| 40 | BMPR1B | 1.05087395 |
| 41 | CASK | 1.04640313 |
| 42 | ACVR1B | 0.99545059 |
| 43 | DYRK2 | 0.98908299 |
| 44 | PIK3CA | 0.96162609 |
| 45 | SGK494 | 0.93531066 |
| 46 | SGK223 | 0.93531066 |
| 47 | IKBKB | 0.90652426 |
| 48 | PASK | 0.88953473 |
| 49 | ERBB3 | 0.85034060 |
| 50 | ZAK | 0.83097344 |
| 51 | TAF1 | 0.82677818 |
| 52 | TGFBR1 | 0.82045702 |
| 53 | SGK3 | 0.78231105 |
| 54 | EIF2AK1 | 0.76199769 |
| 55 | PLK3 | 0.73300972 |
| 56 | PRKCE | 0.70936228 |
| 57 | STK39 | 0.67599989 |
| 58 | AKT3 | 0.67272581 |
| 59 | MAP3K12 | 0.67210715 |
| 60 | TEC | 0.67149333 |
| 61 | CCNB1 | 0.66946559 |
| 62 | MKNK2 | 0.64286993 |
| 63 | ATR | 0.63865396 |
| 64 | DAPK2 | 0.63417761 |
| 65 | PLK2 | 0.63055989 |
| 66 | SIK3 | 0.62956519 |
| 67 | EIF2AK2 | 0.62518507 |
| 68 | MKNK1 | 0.59398037 |
| 69 | ADRBK1 | 0.59033835 |
| 70 | CSNK1G2 | 0.58778315 |
| 71 | STK4 | 0.56371502 |
| 72 | TNIK | 0.53530674 |
| 73 | PRKCH | 0.53057195 |
| 74 | PRKCD | 0.51591899 |
| 75 | OXSR1 | 0.48717782 |
| 76 | CHUK | 0.47349789 |
| 77 | CAMK2A | 0.47238167 |
| 78 | CAMK4 | 0.46342764 |
| 79 | PRKACA | 0.44883775 |
| 80 | NTRK2 | 0.44553638 |
| 81 | ERBB2 | 0.44165431 |
| 82 | CSNK1G3 | 0.43506921 |
| 83 | CAMKK2 | 0.43424866 |
| 84 | INSRR | 0.42728952 |
| 85 | STK11 | 0.42178865 |
| 86 | RPS6KA4 | 0.41684240 |
| 87 | PRKAA2 | 0.41189259 |
| 88 | CSNK1A1 | 0.39563821 |
| 89 | SGK1 | 0.39331661 |
| 90 | CSNK1G1 | 0.38448477 |
| 91 | DAPK1 | 0.38446484 |
| 92 | KSR1 | 0.37750074 |
| 93 | CSNK2A2 | 0.34992331 |
| 94 | PRKG1 | 0.34810930 |
| 95 | CSNK2A1 | 0.34364979 |
| 96 | TIE1 | 0.33141013 |
| 97 | PRKCB | 0.31001165 |
| 98 | STK3 | 0.30873788 |
| 99 | MAP2K4 | 0.29285506 |
| 100 | PRKCQ | 0.28317030 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.34100181 |
| 2 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.31530780 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.30034171 |
| 4 | Sulfur relay system_Homo sapiens_hsa04122 | 3.23821703 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 3.05445283 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 2.77846973 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.72729344 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.58514924 |
| 9 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.18069521 |
| 10 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.02681521 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.00856172 |
| 12 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.98315913 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.91389631 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.91027979 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.88423549 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.83280913 |
| 17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.79669984 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.75509729 |
| 19 | RNA polymerase_Homo sapiens_hsa03020 | 1.73223217 |
| 20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.68260597 |
| 21 | Alzheimers disease_Homo sapiens_hsa05010 | 1.62126999 |
| 22 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.59656937 |
| 23 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.58285381 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.54364454 |
| 25 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.54010928 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.50303385 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.50072588 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.49853015 |
| 29 | Nicotine addiction_Homo sapiens_hsa05033 | 1.46135415 |
| 30 | Taste transduction_Homo sapiens_hsa04742 | 1.46056868 |
| 31 | Asthma_Homo sapiens_hsa05310 | 1.35930029 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.32101127 |
| 33 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.22732280 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.22400960 |
| 35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.20646460 |
| 36 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.14935054 |
| 37 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.10611894 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.09525916 |
| 39 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.01046498 |
| 40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.00506225 |
| 41 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.99978897 |
| 42 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.98624010 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.95705514 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.94099936 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91671602 |
| 46 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.91065143 |
| 47 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.88915302 |
| 48 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.86028687 |
| 49 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.83388506 |
| 50 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.82318334 |
| 51 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.76966139 |
| 52 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.76200155 |
| 53 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.76007114 |
| 54 | Purine metabolism_Homo sapiens_hsa00230 | 0.74647322 |
| 55 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.70888903 |
| 56 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.70694632 |
| 57 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.67977913 |
| 58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.63436467 |
| 59 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.63099586 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62616421 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62568158 |
| 62 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.61956249 |
| 63 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.61588905 |
| 64 | Spliceosome_Homo sapiens_hsa03040 | 0.61278941 |
| 65 | Allograft rejection_Homo sapiens_hsa05330 | 0.60253992 |
| 66 | Circadian rhythm_Homo sapiens_hsa04710 | 0.59363342 |
| 67 | Olfactory transduction_Homo sapiens_hsa04740 | 0.58859682 |
| 68 | GABAergic synapse_Homo sapiens_hsa04727 | 0.58103959 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.54621671 |
| 70 | Morphine addiction_Homo sapiens_hsa05032 | 0.53813558 |
| 71 | RNA transport_Homo sapiens_hsa03013 | 0.53092467 |
| 72 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.53004299 |
| 73 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.52983665 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52665479 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51526165 |
| 76 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.50960755 |
| 77 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.50881959 |
| 78 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.50665163 |
| 79 | Base excision repair_Homo sapiens_hsa03410 | 0.49595570 |
| 80 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.48015110 |
| 81 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.44696951 |
| 82 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.43506842 |
| 83 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.42962978 |
| 84 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42607988 |
| 85 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.41828078 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36100335 |
| 87 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.36048142 |
| 88 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.35317916 |
| 89 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.33728077 |
| 90 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.33136092 |
| 91 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.32982146 |
| 92 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.30504978 |
| 93 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.28995130 |
| 94 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27772809 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.27655425 |
| 96 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.26319639 |
| 97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.23348393 |
| 98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22980453 |
| 99 | Insulin secretion_Homo sapiens_hsa04911 | 0.22930367 |
| 100 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.22828119 |

