

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.79092589 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.54634803 |
| 3 | cytidine catabolic process (GO:0006216) | 7.17214435 |
| 4 | cytidine deamination (GO:0009972) | 7.17214435 |
| 5 | cytidine metabolic process (GO:0046087) | 7.17214435 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.21622782 |
| 7 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.47564512 |
| 8 | actin nucleation (GO:0045010) | 5.06676981 |
| 9 | positive thymic T cell selection (GO:0045059) | 4.26829109 |
| 10 | cellular response to interleukin-15 (GO:0071350) | 4.14902009 |
| 11 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.05938851 |
| 12 | positive T cell selection (GO:0043368) | 3.93438200 |
| 13 | response to interferon-beta (GO:0035456) | 3.81790389 |
| 14 | immunoglobulin mediated immune response (GO:0016064) | 3.74492524 |
| 15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.68732968 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 3.68732968 |
| 17 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.60516617 |
| 18 | negative regulation of viral genome replication (GO:0045071) | 3.56008242 |
| 19 | negative T cell selection (GO:0043383) | 3.51689846 |
| 20 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.51475870 |
| 21 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.48718160 |
| 22 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.46831430 |
| 23 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.46318207 |
| 24 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.45679349 |
| 25 | regulation of chronic inflammatory response (GO:0002676) | 3.44764433 |
| 26 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.44188833 |
| 27 | negative regulation of T cell apoptotic process (GO:0070233) | 3.41268231 |
| 28 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.38936545 |
| 29 | T cell costimulation (GO:0031295) | 3.36759865 |
| 30 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.35537794 |
| 31 | lymphocyte costimulation (GO:0031294) | 3.34339674 |
| 32 | kynurenine metabolic process (GO:0070189) | 3.31627775 |
| 33 | T cell receptor signaling pathway (GO:0050852) | 3.29597732 |
| 34 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.28576613 |
| 35 | response to interleukin-15 (GO:0070672) | 3.26871644 |
| 36 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.25501953 |
| 37 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.21090883 |
| 38 | mast cell activation (GO:0045576) | 3.20013864 |
| 39 | tryptophan catabolic process (GO:0006569) | 3.19725106 |
| 40 | indole-containing compound catabolic process (GO:0042436) | 3.19725106 |
| 41 | indolalkylamine catabolic process (GO:0046218) | 3.19725106 |
| 42 | regulation of interleukin-8 secretion (GO:2000482) | 3.19323341 |
| 43 | proteasome assembly (GO:0043248) | 3.19081898 |
| 44 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.18721192 |
| 45 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.15265976 |
| 46 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.15265976 |
| 47 | protein neddylation (GO:0045116) | 3.14830985 |
| 48 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.14587789 |
| 49 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.14531589 |
| 50 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.14531589 |
| 51 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.14140825 |
| 52 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.14140825 |
| 53 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.14140825 |
| 54 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.13669989 |
| 55 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.13451128 |
| 56 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.12264664 |
| 57 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.09793291 |
| 58 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.07683615 |
| 59 | B cell mediated immunity (GO:0019724) | 3.07526046 |
| 60 | positive regulation of defense response to virus by host (GO:0002230) | 3.07494843 |
| 61 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.06705447 |
| 62 | positive regulation of cell killing (GO:0031343) | 3.06382965 |
| 63 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.01622864 |
| 64 | positive regulation of prostaglandin secretion (GO:0032308) | 3.01152419 |
| 65 | negative thymic T cell selection (GO:0045060) | 3.00581008 |
| 66 | cytolysis (GO:0019835) | 2.98732023 |
| 67 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.96411207 |
| 68 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.96411207 |
| 69 | T cell migration (GO:0072678) | 2.95587201 |
| 70 | positive regulation of B cell differentiation (GO:0045579) | 2.93377825 |
| 71 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.91621201 |
| 72 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.91103870 |
| 73 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.88989804 |
| 74 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.87530682 |
| 75 | regulation of cell killing (GO:0031341) | 2.83573901 |
| 76 | metallo-sulfur cluster assembly (GO:0031163) | 2.82546352 |
| 77 | iron-sulfur cluster assembly (GO:0016226) | 2.82546352 |
| 78 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 2.82215281 |
| 79 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.80829117 |
| 80 | regulation of T cell tolerance induction (GO:0002664) | 2.80225872 |
| 81 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.79085612 |
| 82 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.77840220 |
| 83 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.77619698 |
| 84 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.77237174 |
| 85 | tryptophan metabolic process (GO:0006568) | 2.76460813 |
| 86 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.76413855 |
| 87 | regulation of calcium-mediated signaling (GO:0050848) | 2.74970783 |
| 88 | regulation of regulatory T cell differentiation (GO:0045589) | 2.73947881 |
| 89 | negative regulation of ligase activity (GO:0051352) | 2.72904334 |
| 90 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.72904334 |
| 91 | negative regulation of interleukin-1 production (GO:0032692) | 2.71553720 |
| 92 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.69958984 |
| 93 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.68374093 |
| 94 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.67630801 |
| 95 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.66201752 |
| 96 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.62570254 |
| 97 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.62310428 |
| 98 | thymic T cell selection (GO:0045061) | 2.61254325 |
| 99 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.60947651 |
| 100 | regulation of cellular amine metabolic process (GO:0033238) | 2.60910376 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.19036377 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.79795851 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.38813247 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.18456149 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.91409569 |
| 6 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.60580884 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.57321308 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.56998493 |
| 9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.83451512 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.74555460 |
| 11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.72070881 |
| 12 | MYB_26560356_Chip-Seq_TH2_Human | 2.51493727 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.46359887 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.31550090 |
| 15 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.29925792 |
| 16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.23575607 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.22997759 |
| 18 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.20330195 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.08792402 |
| 20 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.08630630 |
| 21 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.04543511 |
| 22 | GATA3_26560356_Chip-Seq_TH2_Human | 2.03497577 |
| 23 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.96509250 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.95955428 |
| 25 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.92132064 |
| 26 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.76050576 |
| 27 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.75595998 |
| 28 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.74873296 |
| 29 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74367090 |
| 30 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.71147172 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.67873762 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.63884275 |
| 33 | MYB_26560356_Chip-Seq_TH1_Human | 1.59658387 |
| 34 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.54782710 |
| 35 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.49709227 |
| 36 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.47500975 |
| 37 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.46730441 |
| 38 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.40617497 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.39088117 |
| 40 | AR_20517297_ChIP-Seq_VCAP_Human | 1.37328371 |
| 41 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.37005187 |
| 42 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.36006114 |
| 43 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.34028013 |
| 44 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.32564589 |
| 45 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.31334322 |
| 46 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.31291606 |
| 47 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.31178940 |
| 48 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.30532138 |
| 49 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.30085583 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.28640603 |
| 51 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.28640603 |
| 52 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27085817 |
| 53 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.25725237 |
| 54 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.25215981 |
| 55 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24358428 |
| 56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.24144774 |
| 57 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.23561980 |
| 58 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.20552155 |
| 59 | GATA3_26560356_Chip-Seq_TH1_Human | 1.18577970 |
| 60 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.17638271 |
| 61 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.16710949 |
| 62 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.16202423 |
| 63 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.15863120 |
| 64 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.12440089 |
| 65 | UTX_26944678_Chip-Seq_JUKART_Human | 1.11231895 |
| 66 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.10397897 |
| 67 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.06667195 |
| 68 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.06198034 |
| 69 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.05860493 |
| 70 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.05085363 |
| 71 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.04280558 |
| 72 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04248953 |
| 73 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.02304556 |
| 74 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.01806836 |
| 75 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.01469750 |
| 76 | MAF_26560356_Chip-Seq_TH1_Human | 1.01459025 |
| 77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.01139900 |
| 78 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.01139900 |
| 79 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.00715920 |
| 80 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.00642405 |
| 81 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.00303883 |
| 82 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.99674298 |
| 83 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.99574067 |
| 84 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.98999362 |
| 85 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.98658910 |
| 86 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98638927 |
| 87 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.98089363 |
| 88 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.97606047 |
| 89 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.94447366 |
| 90 | EWS_26573619_Chip-Seq_HEK293_Human | 0.91214441 |
| 91 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.89732685 |
| 92 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.89732685 |
| 93 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.89488870 |
| 94 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.89006485 |
| 95 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.88783982 |
| 96 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.88035283 |
| 97 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.87690760 |
| 98 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87537279 |
| 99 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.87324388 |
| 100 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87133643 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.83541752 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.62947492 |
| 3 | MP0009785_altered_susceptibility_to | 3.48325955 |
| 4 | MP0002166_altered_tumor_susceptibility | 3.23383633 |
| 5 | MP0003950_abnormal_plasma_membrane | 2.99414289 |
| 6 | MP0005000_abnormal_immune_tolerance | 2.93919296 |
| 7 | MP0003763_abnormal_thymus_physiology | 2.68012042 |
| 8 | MP0000685_abnormal_immune_system | 2.64554692 |
| 9 | MP0001800_abnormal_humoral_immune | 2.59310605 |
| 10 | MP0003436_decreased_susceptibility_to | 2.54916612 |
| 11 | MP0002006_tumorigenesis | 2.48927228 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 2.48266788 |
| 13 | MP0003724_increased_susceptibility_to | 2.47004562 |
| 14 | MP0002148_abnormal_hypersensitivity_rea | 2.43393106 |
| 15 | MP0002723_abnormal_immune_serum | 2.41243148 |
| 16 | MP0002420_abnormal_adaptive_immunity | 2.38263385 |
| 17 | MP0001819_abnormal_immune_cell | 2.37921636 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.23847683 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 2.23312607 |
| 20 | MP0009333_abnormal_splenocyte_physiolog | 2.09716256 |
| 21 | MP0005025_abnormal_response_to | 2.04993784 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 2.04037561 |
| 23 | MP0001790_abnormal_immune_system | 2.03000241 |
| 24 | MP0005387_immune_system_phenotype | 2.03000241 |
| 25 | MP0003866_abnormal_defecation | 2.01268789 |
| 26 | MP0006082_CNS_inflammation | 1.93581852 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.88384229 |
| 28 | MP0002419_abnormal_innate_immunity | 1.83537853 |
| 29 | MP0003195_calcinosis | 1.81397906 |
| 30 | MP0009764_decreased_sensitivity_to | 1.78927055 |
| 31 | MP0010155_abnormal_intestine_physiology | 1.78692457 |
| 32 | MP0000716_abnormal_immune_system | 1.72788874 |
| 33 | MP0005084_abnormal_gallbladder_morpholo | 1.72535239 |
| 34 | MP0008877_abnormal_DNA_methylation | 1.70659335 |
| 35 | MP0002398_abnormal_bone_marrow | 1.69632021 |
| 36 | MP0004147_increased_porphyrin_level | 1.66223165 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.54617988 |
| 38 | MP0000689_abnormal_spleen_morphology | 1.52109101 |
| 39 | MP0002933_joint_inflammation | 1.47211794 |
| 40 | MP0002722_abnormal_immune_system | 1.43705163 |
| 41 | MP0002405_respiratory_system_inflammati | 1.41183684 |
| 42 | MP0000703_abnormal_thymus_morphology | 1.39764996 |
| 43 | MP0001533_abnormal_skeleton_physiology | 1.37408930 |
| 44 | MP0003011_delayed_dark_adaptation | 1.34742696 |
| 45 | MP0002429_abnormal_blood_cell | 1.32687508 |
| 46 | MP0002102_abnormal_ear_morphology | 1.32465939 |
| 47 | MP0001919_abnormal_reproductive_system | 1.31354425 |
| 48 | MP0001968_abnormal_touch/_nociception | 1.28082533 |
| 49 | MP0002254_reproductive_system_inflammat | 1.27881870 |
| 50 | MP0004947_skin_inflammation | 1.26421174 |
| 51 | MP0006054_spinal_hemorrhage | 1.26111907 |
| 52 | MP0004145_abnormal_muscle_electrophysio | 1.23154210 |
| 53 | MP0001853_heart_inflammation | 1.21260572 |
| 54 | MP0003448_altered_tumor_morphology | 1.16860002 |
| 55 | MP0008872_abnormal_physiological_respon | 1.16809200 |
| 56 | MP0005645_abnormal_hypothalamus_physiol | 1.14991894 |
| 57 | MP0005075_abnormal_melanosome_morpholog | 1.14276560 |
| 58 | MP0001873_stomach_inflammation | 1.12739002 |
| 59 | MP0002736_abnormal_nociception_after | 1.12536130 |
| 60 | MP0003252_abnormal_bile_duct | 1.11086616 |
| 61 | MP0008058_abnormal_DNA_repair | 1.10900981 |
| 62 | MP0008469_abnormal_protein_level | 1.03403950 |
| 63 | MP0005389_reproductive_system_phenotype | 1.02297709 |
| 64 | MP0009763_increased_sensitivity_to | 1.00364732 |
| 65 | MP0005253_abnormal_eye_physiology | 0.96991359 |
| 66 | MP0005551_abnormal_eye_electrophysiolog | 0.96144153 |
| 67 | MP0001905_abnormal_dopamine_level | 0.92541005 |
| 68 | MP0002009_preneoplasia | 0.92522385 |
| 69 | MP0005464_abnormal_platelet_physiology | 0.91411849 |
| 70 | MP0003806_abnormal_nucleotide_metabolis | 0.88400128 |
| 71 | MP0005166_decreased_susceptibility_to | 0.87639902 |
| 72 | MP0003137_abnormal_impulse_conducting | 0.82851124 |
| 73 | MP0005165_increased_susceptibility_to | 0.82226177 |
| 74 | MP0002876_abnormal_thyroid_physiology | 0.82223928 |
| 75 | MP0005410_abnormal_fertilization | 0.79648389 |
| 76 | MP0003075_altered_response_to | 0.79450996 |
| 77 | MP0003786_premature_aging | 0.75632265 |
| 78 | MP0002019_abnormal_tumor_incidence | 0.75449252 |
| 79 | MP0005646_abnormal_pituitary_gland | 0.74253434 |
| 80 | MP0005647_abnormal_sex_gland | 0.73332959 |
| 81 | MP0000465_gastrointestinal_hemorrhage | 0.71346678 |
| 82 | MP0000858_altered_metastatic_potential | 0.70827772 |
| 83 | MP0005636_abnormal_mineral_homeostasis | 0.70592789 |
| 84 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.69282667 |
| 85 | MP0001542_abnormal_bone_strength | 0.69157630 |
| 86 | MP0001986_abnormal_taste_sensitivity | 0.67949065 |
| 87 | MP0004885_abnormal_endolymph | 0.64797276 |
| 88 | MP0003878_abnormal_ear_physiology | 0.63105951 |
| 89 | MP0005377_hearing/vestibular/ear_phenot | 0.63105951 |
| 90 | MP0002837_dystrophic_cardiac_calcinosis | 0.62689448 |
| 91 | MP0005390_skeleton_phenotype | 0.62611121 |
| 92 | MP0006036_abnormal_mitochondrial_physio | 0.61276607 |
| 93 | MP0009643_abnormal_urine_homeostasis | 0.59276727 |
| 94 | MP0001501_abnormal_sleep_pattern | 0.58905849 |
| 95 | MP0002693_abnormal_pancreas_physiology | 0.55773670 |
| 96 | MP0001119_abnormal_female_reproductive | 0.52737734 |
| 97 | MP0001970_abnormal_pain_threshold | 0.51345093 |
| 98 | MP0008873_increased_physiological_sensi | 0.50853218 |
| 99 | MP0002136_abnormal_kidney_physiology | 0.48832797 |
| 100 | MP0002139_abnormal_hepatobiliary_system | 0.48488653 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.97135642 |
| 2 | T lymphocytopenia (HP:0005403) | 4.48863615 |
| 3 | IgG deficiency (HP:0004315) | 4.17416201 |
| 4 | Abnormality of T cell number (HP:0011839) | 4.12623768 |
| 5 | Autoimmune hemolytic anemia (HP:0001890) | 3.92977986 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.70116004 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.61189154 |
| 8 | Stomatitis (HP:0010280) | 3.58922143 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.43705868 |
| 10 | Hypoproteinemia (HP:0003075) | 3.41688007 |
| 11 | Abnormality of the prostate (HP:0008775) | 3.41415586 |
| 12 | Abnormality of T cells (HP:0002843) | 3.38081085 |
| 13 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.34581676 |
| 14 | Autoimmune thrombocytopenia (HP:0001973) | 3.22666046 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.20017220 |
| 16 | Severe combined immunodeficiency (HP:0004430) | 3.15281609 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.12794947 |
| 18 | Increased CSF lactate (HP:0002490) | 3.07895525 |
| 19 | Aplastic anemia (HP:0001915) | 2.99000192 |
| 20 | Abnormality of B cell number (HP:0010975) | 2.93550892 |
| 21 | Acute encephalopathy (HP:0006846) | 2.85743071 |
| 22 | Cerebral palsy (HP:0100021) | 2.85173582 |
| 23 | Prostate neoplasm (HP:0100787) | 2.77255465 |
| 24 | Abolished electroretinogram (ERG) (HP:0000550) | 2.76386744 |
| 25 | Hepatic necrosis (HP:0002605) | 2.74770119 |
| 26 | Congenital stationary night blindness (HP:0007642) | 2.73086041 |
| 27 | Increased IgM level (HP:0003496) | 2.72454404 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.70879536 |
| 29 | Thyroiditis (HP:0100646) | 2.69983282 |
| 30 | B lymphocytopenia (HP:0010976) | 2.68428745 |
| 31 | Myositis (HP:0100614) | 2.58736687 |
| 32 | Cerebral edema (HP:0002181) | 2.58000357 |
| 33 | Pustule (HP:0200039) | 2.56700174 |
| 34 | Decreased central vision (HP:0007663) | 2.55993256 |
| 35 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.55780933 |
| 36 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.55780933 |
| 37 | Abnormality of eosinophils (HP:0001879) | 2.54545614 |
| 38 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.53913943 |
| 39 | Testicular atrophy (HP:0000029) | 2.51757777 |
| 40 | Recurrent bronchitis (HP:0002837) | 2.50444623 |
| 41 | Combined immunodeficiency (HP:0005387) | 2.49646061 |
| 42 | Chronic diarrhea (HP:0002028) | 2.47892659 |
| 43 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.45786654 |
| 44 | Gastrointestinal infarctions (HP:0005244) | 2.42847953 |
| 45 | Fibular aplasia (HP:0002990) | 2.42749037 |
| 46 | Hemoptysis (HP:0002105) | 2.42504790 |
| 47 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.40025250 |
| 48 | Exertional dyspnea (HP:0002875) | 2.38197640 |
| 49 | Increased hepatocellular lipid droplets (HP:0006565) | 2.37124024 |
| 50 | Recurrent viral infections (HP:0004429) | 2.33134915 |
| 51 | Eosinophilia (HP:0001880) | 2.32135980 |
| 52 | Meningitis (HP:0001287) | 2.30147003 |
| 53 | Vasculitis (HP:0002633) | 2.29066547 |
| 54 | 3-Methylglutaconic aciduria (HP:0003535) | 2.25696983 |
| 55 | Attenuation of retinal blood vessels (HP:0007843) | 2.25672101 |
| 56 | Renal Fanconi syndrome (HP:0001994) | 2.24243080 |
| 57 | Visual hallucinations (HP:0002367) | 2.24042014 |
| 58 | Obstructive lung disease (HP:0006536) | 2.23796659 |
| 59 | Chronic obstructive pulmonary disease (HP:0006510) | 2.23796659 |
| 60 | Leukocytosis (HP:0001974) | 2.21996385 |
| 61 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.20538160 |
| 62 | Abnormality of T cell physiology (HP:0011840) | 2.19921272 |
| 63 | Recurrent cutaneous fungal infections (HP:0011370) | 2.19244943 |
| 64 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.19244943 |
| 65 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.15503810 |
| 66 | Pulmonary infiltrates (HP:0002113) | 2.15392959 |
| 67 | Lymphopenia (HP:0001888) | 2.13750104 |
| 68 | Abnormal albumin level (HP:0012116) | 2.13442598 |
| 69 | Hypoalbuminemia (HP:0003073) | 2.13442598 |
| 70 | Recurrent fungal infections (HP:0002841) | 2.12616847 |
| 71 | Tetraparesis (HP:0002273) | 2.10089613 |
| 72 | Increased intramyocellular lipid droplets (HP:0012240) | 2.09292581 |
| 73 | Lactic acidosis (HP:0003128) | 2.09100753 |
| 74 | Renal cortical cysts (HP:0000803) | 2.07173292 |
| 75 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.04895707 |
| 76 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.02195268 |
| 77 | Lipid accumulation in hepatocytes (HP:0006561) | 2.01603585 |
| 78 | Parakeratosis (HP:0001036) | 1.98283567 |
| 79 | Increased serum lactate (HP:0002151) | 1.96578820 |
| 80 | Optic disc pallor (HP:0000543) | 1.95773681 |
| 81 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.93843912 |
| 82 | Chronic sinusitis (HP:0011109) | 1.92689149 |
| 83 | Constricted visual fields (HP:0001133) | 1.91391054 |
| 84 | Abnormality of the pleura (HP:0002103) | 1.90911979 |
| 85 | Panhypogammaglobulinemia (HP:0003139) | 1.90675637 |
| 86 | Short tibia (HP:0005736) | 1.90507293 |
| 87 | Encephalitis (HP:0002383) | 1.90006622 |
| 88 | Respiratory failure (HP:0002878) | 1.89332900 |
| 89 | Gangrene (HP:0100758) | 1.88136334 |
| 90 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.88084859 |
| 91 | Generalized aminoaciduria (HP:0002909) | 1.86881327 |
| 92 | Facial diplegia (HP:0001349) | 1.86761899 |
| 93 | Granulocytopenia (HP:0001913) | 1.86623837 |
| 94 | Lymphoma (HP:0002665) | 1.86311927 |
| 95 | Hypothermia (HP:0002045) | 1.84061665 |
| 96 | Pancreatic cysts (HP:0001737) | 1.83308097 |
| 97 | Keratoconjunctivitis (HP:0001096) | 1.81182358 |
| 98 | Bronchitis (HP:0012387) | 1.80605458 |
| 99 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.80319244 |
| 100 | Retrobulbar optic neuritis (HP:0100654) | 1.79020813 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 4.27144241 |
| 2 | TESK2 | 3.55162195 |
| 3 | TXK | 3.36193611 |
| 4 | MAP4K1 | 3.02788524 |
| 5 | MAP3K12 | 2.84019612 |
| 6 | GRK6 | 2.72285120 |
| 7 | BCKDK | 2.39746227 |
| 8 | EIF2AK3 | 2.24056126 |
| 9 | TLK1 | 2.23989788 |
| 10 | TAOK3 | 2.22061559 |
| 11 | MAP4K2 | 2.15741804 |
| 12 | BMPR2 | 2.14501960 |
| 13 | CDK19 | 2.05332620 |
| 14 | ZAK | 1.95738350 |
| 15 | MST4 | 1.87930789 |
| 16 | INSRR | 1.74867181 |
| 17 | FES | 1.72707529 |
| 18 | MYLK | 1.68967223 |
| 19 | FRK | 1.67366473 |
| 20 | SYK | 1.65409214 |
| 21 | KIT | 1.64269102 |
| 22 | TBK1 | 1.63320986 |
| 23 | ADRBK2 | 1.57130550 |
| 24 | ITK | 1.56816304 |
| 25 | SCYL2 | 1.49745609 |
| 26 | GRK1 | 1.48740940 |
| 27 | IKBKB | 1.44321095 |
| 28 | MAPKAPK3 | 1.41855569 |
| 29 | NUAK1 | 1.41757144 |
| 30 | BTK | 1.41658394 |
| 31 | MATK | 1.40785885 |
| 32 | MAP3K14 | 1.39233137 |
| 33 | ZAP70 | 1.32245706 |
| 34 | TEC | 1.32244531 |
| 35 | PASK | 1.29387930 |
| 36 | LIMK1 | 1.26711625 |
| 37 | EIF2AK1 | 1.25688991 |
| 38 | LCK | 1.19921879 |
| 39 | MUSK | 1.15955595 |
| 40 | DAPK1 | 1.13550431 |
| 41 | ERBB3 | 1.07987514 |
| 42 | IKBKE | 1.07572095 |
| 43 | LYN | 1.07546185 |
| 44 | VRK2 | 1.04777044 |
| 45 | NEK1 | 1.04308650 |
| 46 | TESK1 | 1.04300334 |
| 47 | VRK1 | 1.04105701 |
| 48 | CAMKK2 | 1.02424011 |
| 49 | TIE1 | 1.02248135 |
| 50 | PRKCQ | 0.93617580 |
| 51 | FLT3 | 0.92214006 |
| 52 | BMPR1B | 0.91383758 |
| 53 | CSF1R | 0.85200490 |
| 54 | BUB1 | 0.83051765 |
| 55 | EIF2AK2 | 0.82078312 |
| 56 | OXSR1 | 0.80821151 |
| 57 | JAK3 | 0.79567166 |
| 58 | CAMKK1 | 0.78555152 |
| 59 | TRIM28 | 0.77454545 |
| 60 | IGF1R | 0.75076502 |
| 61 | JAK1 | 0.72303659 |
| 62 | NTRK1 | 0.69332885 |
| 63 | GRK7 | 0.68830643 |
| 64 | MAP3K11 | 0.66217548 |
| 65 | WNK3 | 0.65518502 |
| 66 | PIK3CA | 0.64345604 |
| 67 | PLK2 | 0.62480544 |
| 68 | CSNK1G3 | 0.60686030 |
| 69 | HCK | 0.56899450 |
| 70 | CSK | 0.56623894 |
| 71 | CSNK1A1L | 0.55383531 |
| 72 | MAP2K2 | 0.55278833 |
| 73 | ACVR1B | 0.54307478 |
| 74 | ROCK1 | 0.53319255 |
| 75 | RPS6KA4 | 0.49345554 |
| 76 | GRK5 | 0.46729368 |
| 77 | ADRBK1 | 0.46486854 |
| 78 | PAK1 | 0.46483787 |
| 79 | MAP2K7 | 0.46172604 |
| 80 | MAP3K4 | 0.42884150 |
| 81 | ABL1 | 0.42727857 |
| 82 | TRPM7 | 0.42325008 |
| 83 | TNK2 | 0.41083638 |
| 84 | MAPK13 | 0.38826532 |
| 85 | PIM1 | 0.38007157 |
| 86 | OBSCN | 0.37749681 |
| 87 | ILK | 0.37489860 |
| 88 | PRKCA | 0.37445997 |
| 89 | RPS6KA5 | 0.35797670 |
| 90 | INSR | 0.34587559 |
| 91 | STK16 | 0.33335036 |
| 92 | CSNK1G1 | 0.33317235 |
| 93 | BLK | 0.33093494 |
| 94 | EGFR | 0.32166630 |
| 95 | FYN | 0.32126236 |
| 96 | RIPK4 | 0.31501506 |
| 97 | PHKG1 | 0.31097153 |
| 98 | PHKG2 | 0.31097153 |
| 99 | MAP3K5 | 0.31008396 |
| 100 | TGFBR1 | 0.27994977 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.30238619 |
| 2 | Caffeine metabolism_Homo sapiens_hsa00232 | 4.10299630 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.07717081 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.86231482 |
| 5 | Asthma_Homo sapiens_hsa05310 | 3.73864115 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.72459402 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.41756779 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.14497273 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.10519627 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.09021288 |
| 11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.48174850 |
| 12 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.08379525 |
| 13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.01817833 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.96493552 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.93043023 |
| 16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.89262233 |
| 17 | Viral myocarditis_Homo sapiens_hsa05416 | 1.85053405 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.65991199 |
| 19 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.63538351 |
| 20 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.63410882 |
| 21 | RNA polymerase_Homo sapiens_hsa03020 | 1.46062294 |
| 22 | Alzheimers disease_Homo sapiens_hsa05010 | 1.31298444 |
| 23 | Leishmaniasis_Homo sapiens_hsa05140 | 1.30311945 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.25779855 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.19060392 |
| 26 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.14925296 |
| 27 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.05559616 |
| 28 | Phototransduction_Homo sapiens_hsa04744 | 1.03490036 |
| 29 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.02014824 |
| 30 | Huntingtons disease_Homo sapiens_hsa05016 | 1.01769922 |
| 31 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.01312985 |
| 32 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.97761392 |
| 33 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.95884279 |
| 34 | Ribosome_Homo sapiens_hsa03010 | 0.91675970 |
| 35 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.88917380 |
| 36 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.88333891 |
| 37 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.87864877 |
| 38 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.87740694 |
| 39 | Measles_Homo sapiens_hsa05162 | 0.85703053 |
| 40 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.83933602 |
| 41 | RNA degradation_Homo sapiens_hsa03018 | 0.82532658 |
| 42 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.77808036 |
| 43 | Shigellosis_Homo sapiens_hsa05131 | 0.77042108 |
| 44 | Malaria_Homo sapiens_hsa05144 | 0.75008428 |
| 45 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.72511989 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.71167385 |
| 47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.69790348 |
| 48 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.68823108 |
| 49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.68665859 |
| 50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.62534631 |
| 51 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.62085980 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61663573 |
| 53 | Peroxisome_Homo sapiens_hsa04146 | 0.58761610 |
| 54 | DNA replication_Homo sapiens_hsa03030 | 0.57470741 |
| 55 | Pertussis_Homo sapiens_hsa05133 | 0.56023909 |
| 56 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.55867083 |
| 57 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55489486 |
| 58 | Purine metabolism_Homo sapiens_hsa00230 | 0.52593883 |
| 59 | Legionellosis_Homo sapiens_hsa05134 | 0.52459403 |
| 60 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51403312 |
| 61 | Salmonella infection_Homo sapiens_hsa05132 | 0.51373024 |
| 62 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.50685351 |
| 63 | Olfactory transduction_Homo sapiens_hsa04740 | 0.49311858 |
| 64 | Mismatch repair_Homo sapiens_hsa03430 | 0.49152374 |
| 65 | Influenza A_Homo sapiens_hsa05164 | 0.49128116 |
| 66 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.47782721 |
| 67 | Tuberculosis_Homo sapiens_hsa05152 | 0.47420055 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45562955 |
| 69 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.45196874 |
| 70 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.44320610 |
| 71 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.43810261 |
| 72 | Phagosome_Homo sapiens_hsa04145 | 0.43750998 |
| 73 | Basal transcription factors_Homo sapiens_hsa03022 | 0.43024579 |
| 74 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.42932641 |
| 75 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.42751246 |
| 76 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.41522143 |
| 77 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.38336422 |
| 78 | Spliceosome_Homo sapiens_hsa03040 | 0.38103262 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37958527 |
| 80 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.34811364 |
| 81 | Homologous recombination_Homo sapiens_hsa03440 | 0.33569251 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.33301814 |
| 83 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.31004070 |
| 84 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.30921732 |
| 85 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.30177607 |
| 86 | HTLV-I infection_Homo sapiens_hsa05166 | 0.29994850 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27964683 |
| 88 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.27894914 |
| 89 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.23603806 |
| 90 | Metabolic pathways_Homo sapiens_hsa01100 | 0.21521241 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.21160631 |
| 92 | Taste transduction_Homo sapiens_hsa04742 | 0.21112922 |
| 93 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.19721583 |
| 94 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.18434610 |
| 95 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.17565920 |
| 96 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.14342992 |
| 97 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.13251432 |
| 98 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.11764407 |
| 99 | Base excision repair_Homo sapiens_hsa03410 | 0.11278835 |
| 100 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.10806229 |

