GLTPD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.55206939
2L-phenylalanine catabolic process (GO:0006559)7.55206939
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.24243725
4L-phenylalanine metabolic process (GO:0006558)7.24243725
5aromatic amino acid family catabolic process (GO:0009074)6.81921342
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.51151659
7indole-containing compound catabolic process (GO:0042436)6.20124921
8indolalkylamine catabolic process (GO:0046218)6.20124921
9tryptophan catabolic process (GO:0006569)6.20124921
10kynurenine metabolic process (GO:0070189)6.07655643
11bile acid biosynthetic process (GO:0006699)5.96402442
12regulation of plasminogen activation (GO:0010755)5.88440445
13intestinal cholesterol absorption (GO:0030299)5.83987290
14tryptophan metabolic process (GO:0006568)5.83274450
15glyoxylate metabolic process (GO:0046487)5.81173100
16negative regulation of fibrinolysis (GO:0051918)5.75406934
17high-density lipoprotein particle remodeling (GO:0034375)5.74584282
18epoxygenase P450 pathway (GO:0019373)5.71356997
19urea cycle (GO:0000050)5.68448957
20urea metabolic process (GO:0019627)5.68448957
21regulation of fibrinolysis (GO:0051917)5.54965300
22alpha-linolenic acid metabolic process (GO:0036109)5.53003190
23protein carboxylation (GO:0018214)5.48309885
24peptidyl-glutamic acid carboxylation (GO:0017187)5.48309885
25regulation of protein activation cascade (GO:2000257)5.44217550
26complement activation, alternative pathway (GO:0006957)5.40723865
27sulfur amino acid catabolic process (GO:0000098)5.31843352
28cysteine metabolic process (GO:0006534)5.28521864
29nitrogen cycle metabolic process (GO:0071941)5.22730877
30exogenous drug catabolic process (GO:0042738)5.17253417
31serine family amino acid catabolic process (GO:0009071)5.12889019
32omega-hydroxylase P450 pathway (GO:0097267)5.11642973
33bile acid metabolic process (GO:0008206)5.08544100
34regulation of complement activation (GO:0030449)5.06898503
35reverse cholesterol transport (GO:0043691)5.04117664
36regulation of cholesterol esterification (GO:0010872)5.01031570
37positive regulation of fatty acid biosynthetic process (GO:0045723)5.00913817
38aromatic amino acid family metabolic process (GO:0009072)4.96023578
39regulation of triglyceride catabolic process (GO:0010896)4.94574330
40proline metabolic process (GO:0006560)4.91068480
41plasma lipoprotein particle remodeling (GO:0034369)4.90617734
42protein-lipid complex remodeling (GO:0034368)4.90617734
43macromolecular complex remodeling (GO:0034367)4.90617734
44fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.88909614
45tyrosine metabolic process (GO:0006570)4.77580953
46phospholipid efflux (GO:0033700)4.73294216
47acylglycerol homeostasis (GO:0055090)4.69268454
48triglyceride homeostasis (GO:0070328)4.69268454
49negative regulation of sterol transport (GO:0032372)4.64324123
50negative regulation of cholesterol transport (GO:0032375)4.64324123
51homocysteine metabolic process (GO:0050667)4.64267041
52alpha-amino acid catabolic process (GO:1901606)4.62712446
53protein-lipid complex subunit organization (GO:0071825)4.58109908
54amino-acid betaine metabolic process (GO:0006577)4.54047265
55lysine catabolic process (GO:0006554)4.53774743
56lysine metabolic process (GO:0006553)4.53774743
57plasma lipoprotein particle clearance (GO:0034381)4.50683753
58cellular ketone body metabolic process (GO:0046950)4.46178403
59coenzyme catabolic process (GO:0009109)4.43771100
60glycine metabolic process (GO:0006544)4.43440787
61indolalkylamine metabolic process (GO:0006586)4.39023042
62imidazole-containing compound metabolic process (GO:0052803)4.36962722
63bile acid and bile salt transport (GO:0015721)4.35850267
64cholesterol efflux (GO:0033344)4.32668039
65cellular biogenic amine catabolic process (GO:0042402)4.30419988
66amine catabolic process (GO:0009310)4.30419988
67negative regulation of hemostasis (GO:1900047)4.28312211
68negative regulation of blood coagulation (GO:0030195)4.28312211
69cellular amino acid catabolic process (GO:0009063)4.25489006
70glutamate metabolic process (GO:0006536)4.24065976
71cellular glucuronidation (GO:0052695)4.21858096
72serine family amino acid metabolic process (GO:0009069)4.17888066
73benzene-containing compound metabolic process (GO:0042537)4.12674633
74flavonoid metabolic process (GO:0009812)4.11641582
75plasma lipoprotein particle assembly (GO:0034377)4.10684043
76fibrinolysis (GO:0042730)4.09424397
77ethanol oxidation (GO:0006069)4.07514539
78regulation of apoptotic cell clearance (GO:2000425)4.05901309
79cellular modified amino acid catabolic process (GO:0042219)4.05055335
80arginine metabolic process (GO:0006525)4.04781312
81dicarboxylic acid biosynthetic process (GO:0043650)4.04322979
82drug metabolic process (GO:0017144)4.04037826
83low-density lipoprotein particle remodeling (GO:0034374)4.02897404
84positive regulation of blood coagulation (GO:0030194)4.02603083
85positive regulation of hemostasis (GO:1900048)4.02603083
86serine family amino acid biosynthetic process (GO:0009070)4.02195138
87positive regulation of heterotypic cell-cell adhesion (GO:0034116)4.00688035
88aldehyde catabolic process (GO:0046185)3.98237064
89positive regulation of lipoprotein lipase activity (GO:0051006)3.94529186
90positive regulation of triglyceride lipase activity (GO:0061365)3.94529186
91blood coagulation, intrinsic pathway (GO:0007597)3.92236410
92negative regulation of coagulation (GO:0050819)3.92062401
93ketone body metabolic process (GO:1902224)3.86169982
94complement activation, classical pathway (GO:0006958)3.84173087
95cofactor catabolic process (GO:0051187)3.83370962
96drug catabolic process (GO:0042737)3.82453541
97regulation of humoral immune response (GO:0002920)3.80619499
98negative regulation of lipase activity (GO:0060192)3.79415469
99complement activation (GO:0006956)3.78422802
100negative regulation of wound healing (GO:0061045)3.78216900
101protein activation cascade (GO:0072376)3.78190136
102very-low-density lipoprotein particle assembly (GO:0034379)3.78076988
103cholesterol homeostasis (GO:0042632)3.77473229
104positive regulation of lipid catabolic process (GO:0050996)3.76879120
105cytolysis (GO:0019835)3.74727516
106lipoprotein metabolic process (GO:0042157)3.74445763
107negative regulation of lipid transport (GO:0032369)3.74392972
108uronic acid metabolic process (GO:0006063)3.74358237
109glucuronate metabolic process (GO:0019585)3.74358237
110phospholipid homeostasis (GO:0055091)3.73295890
111plasma lipoprotein particle organization (GO:0071827)3.72310014
112carboxylic acid catabolic process (GO:0046395)3.71638836
113organic acid catabolic process (GO:0016054)3.71638836
114regulation of cholesterol biosynthetic process (GO:0045540)3.71478455
115positive regulation of coagulation (GO:0050820)3.71419444
116sterol homeostasis (GO:0055092)3.71067769
117regulation of bile acid biosynthetic process (GO:0070857)3.68035450
118protein-lipid complex assembly (GO:0065005)3.67886061
119regulation of fatty acid biosynthetic process (GO:0042304)3.67091881
120cholesterol transport (GO:0030301)3.65216372
121sterol transport (GO:0015918)3.65216372
122regulation of cholesterol homeostasis (GO:2000188)3.64521015
123acetyl-CoA metabolic process (GO:0006084)3.64339707
124short-chain fatty acid metabolic process (GO:0046459)3.63125205
125acute-phase response (GO:0006953)3.61196092
126NAD biosynthetic process (GO:0009435)3.60636303
127positive regulation of steroid metabolic process (GO:0045940)3.59872057
128ethanol metabolic process (GO:0006067)3.55764164
129intestinal absorption (GO:0050892)3.55617063
130acute inflammatory response (GO:0002526)3.44857001
131regulation of lipoprotein particle clearance (GO:0010984)3.43525764
132negative regulation of protein activation cascade (GO:2000258)3.42453967
133negative regulation of fatty acid biosynthetic process (GO:0045717)3.30151043
134regulation of cholesterol metabolic process (GO:0090181)3.26694733
135regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.26587540
136regulation of sterol transport (GO:0032371)3.20154188

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.37832398
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.21517626
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse7.05474062
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.48492753
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.30444586
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.17270936
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.87430973
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.05630880
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.04946768
10TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.04344723
11HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.00282223
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse12.0561737
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.93642541
14TP63_17297297_ChIP-ChIP_HaCaT_Human1.88247451
15RACK7_27058665_Chip-Seq_MCF-7_Human1.72704633
16TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.66278599
17FOXA2_19822575_ChIP-Seq_HepG2_Human1.59369156
18HTT_18923047_ChIP-ChIP_STHdh_Human1.58103228
19VDR_21846776_ChIP-Seq_THP-1_Human1.52053532
20TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51941768
21CLOCK_20551151_ChIP-Seq_293T_Human1.50324108
22* ELK3_25401928_ChIP-Seq_HUVEC_Human1.48877444
23SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.45620811
24SRY_22984422_ChIP-ChIP_TESTIS_Rat1.42266112
25HNF4A_19822575_ChIP-Seq_HepG2_Human1.40571230
26GATA1_22025678_ChIP-Seq_K562_Human1.39766427
27P68_20966046_ChIP-Seq_HELA_Human1.37104128
28TET1_21451524_ChIP-Seq_MESCs_Mouse1.34700087
29EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.33954440
30NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.32882822
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.30895781
32SMC4_20622854_ChIP-Seq_HELA_Human1.29224812
33TRIM28_21343339_ChIP-Seq_HEK293_Human1.27724393
34MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25656339
35KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.25554887
36DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24852905
37* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.24064232
38* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.19170915
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.18688250
40STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.17985773
41TCF7_22412390_ChIP-Seq_EML_Mouse1.17890520
42TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.15268687
43KDM2B_26808549_Chip-Seq_K562_Human1.13375235
44EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.12552749
45ELF1_20517297_ChIP-Seq_JURKAT_Human1.12156968
46BCOR_27268052_Chip-Seq_Bcells_Human1.11725564
47ESR1_15608294_ChIP-ChIP_MCF-7_Human1.08771781
48CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.06900473
49* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.05493116
50SA1_27219007_Chip-Seq_ERYTHROID_Human1.05117287
51CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03362670
52CREB1_26743006_Chip-Seq_LNCaP_Human1.03046210
53ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02235381
54* CTCF_27219007_Chip-Seq_Bcells_Human1.02183616
55IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00985499
56KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.95761731
57BCL6_27268052_Chip-Seq_Bcells_Human0.95613726
58* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.95338306
59HIF1A_21447827_ChIP-Seq_MCF-7_Human0.94351077
60TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93317534
61E2F1_20622854_ChIP-Seq_HELA_Human0.92975379
62PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92735278
63TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.92386090
64PHF8_20622854_ChIP-Seq_HELA_Human0.92206226
65MYC_22102868_ChIP-Seq_BL_Human0.91829364
66ZFP281_18757296_ChIP-ChIP_E14_Mouse0.89761741
67SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.89665460
68SOX2_27498859_Chip-Seq_STOMACH_Mouse0.88984871
69ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88622936
70JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.88413248
71PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.86570798
72TP53_22127205_ChIP-Seq_IMR90_Human0.86501091
73SA1_27219007_Chip-Seq_Bcells_Human0.86497311
74STAT6_21828071_ChIP-Seq_BEAS2B_Human0.86098885
75KDM2B_26808549_Chip-Seq_DND41_Human0.85477774
76IRF8_22096565_ChIP-ChIP_GC-B_Human0.85301065
77ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.84773496
78RARG_19884340_ChIP-ChIP_MEFs_Mouse0.84527050
79* ATF3_27146783_Chip-Seq_COLON_Human0.84204404
80KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.83379664
81CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.83290415
82GATA1_22383799_ChIP-Seq_G1ME_Mouse0.81655030
83AUTS2_25519132_ChIP-Seq_293T-REX_Human0.81486332
84PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80169497
85P63_26484246_Chip-Seq_KERATINOCYTES_Human0.79575506
86GATA4_25053715_ChIP-Seq_YYC3_Human0.78764257
87ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.78668363
88GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.78308561
89SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.78192005
90KAP1_22055183_ChIP-Seq_ESCs_Mouse0.77890830
91RUNX1_27514584_Chip-Seq_MCF-7_Human0.77283274
92BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74747205
93SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.73967225
94* RARA_24833708_ChIP-Seq_LIVER_Mouse0.72539737
95CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.69566779
96ZNF263_19887448_ChIP-Seq_K562_Human0.69201131
97Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.68424670
98ESR2_21235772_ChIP-Seq_MCF-7_Human0.65945293
99SALL4_18804426_ChIP-ChIP_XEN_Mouse0.65566196
100AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.65237992
101RARB_24833708_ChIP-Seq_LIVER_Mouse0.64949954
102RAD21_21589869_ChIP-Seq_MESCs_Mouse0.63407277
103NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.62853399
104NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.62565574
105NRF2_20460467_ChIP-Seq_MEFs_Mouse0.62565574
106RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.62502924
107NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.62295488
108NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.59749680
109CEBPB_22108803_ChIP-Seq_LS180_Human0.56543494
110* BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.55973759
111LXR_22292898_ChIP-Seq_THP-1_Human0.55516561
112EGR1_19032775_ChIP-ChIP_M12_Human0.54698680
113PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.54282220
114STAT3_1855785_ChIP-Seq_MESCs_Mouse0.53807724
115MYC_19915707_ChIP-ChIP_AK7_Human0.52523857
116AR_20517297_ChIP-Seq_VCAP_Human0.52326780
117FOXA1_25552417_ChIP-Seq_VCAP_Human0.50940135
118FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.49392884
119FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.49305407
120ESET_19884257_ChIP-Seq_ESCs_Mouse0.48264209
121CBP_21632823_ChIP-Seq_H3396_Human0.47124396
122STAT1_17558387_ChIP-Seq_HELA_Human0.46267884
123P53_21459846_ChIP-Seq_SAOS-2_Human0.46136052
124CDX2_20551321_ChIP-Seq_CACO-2_Human0.45757770
125ESR1_21235772_ChIP-Seq_MCF-7_Human0.44436106
126PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.44367457
127PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.44252546
128TAF2_19829295_ChIP-Seq_ESCs_Human0.43149511
129PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.42971937
130GATA1_19941827_ChIP-Seq_MEL_Mouse0.42895863
131SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.42759737
132E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.42126765
133TAF15_26573619_Chip-Seq_HEK293_Human0.40816298
134GATA1_19941826_ChIP-Seq_K562_Human0.40151785
135CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.39637948
136STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.39589132
137ERG_21242973_ChIP-ChIP_JURKAT_Human0.39528227
138FOXO3_23340844_ChIP-Seq_DLD1_Human0.39475031
139MYC_27129775_Chip-Seq_CORNEA_Mouse0.38941903
140FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.38514166
141FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.38075484
142BCAT_22108803_ChIP-Seq_LS180_Human0.38021254
143GATA2_19941826_ChIP-Seq_K562_Human0.37697171
144GATA6_25053715_ChIP-Seq_YYC3_Human0.37676615
145PPAR_26484153_Chip-Seq_NCI-H1993_Human0.37412073
146ESR1_20079471_ChIP-ChIP_T-47D_Human0.37248759
147SPI1_26923725_Chip-Seq_HPCs_Mouse0.36690382
148GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.36443029
149SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.35870408
150LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.35054588
151CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.34715777
152NCOR_22424771_ChIP-Seq_293T_Human0.34439187
153FOXH1_21741376_ChIP-Seq_EPCs_Human0.33459737
154OCT4_20526341_ChIP-Seq_ESCs_Human0.33222089

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.35954811
2MP0005360_urolithiasis7.53990133
3MP0005085_abnormal_gallbladder_physiolo6.41101312
4MP0005365_abnormal_bile_salt6.16901789
5MP0008875_abnormal_xenobiotic_pharmacok5.02017101
6MP0003806_abnormal_nucleotide_metabolis4.35274512
7MP0003252_abnormal_bile_duct3.86540153
8MP0010329_abnormal_lipoprotein_level3.62718735
9MP0009840_abnormal_foam_cell3.39278605
10MP0005083_abnormal_biliary_tract3.13309714
11MP0003195_calcinosis2.82893108
12MP0005332_abnormal_amino_acid2.74823738
13MP0001666_abnormal_nutrient_absorption2.60394654
14MP0005058_abnormal_lysosome_morphology2.53218719
15MP0003191_abnormal_cellular_cholesterol2.43399043
16MP0000609_abnormal_liver_physiology2.16647279
17MP0004019_abnormal_vitamin_homeostasis2.11123791
18MP0002118_abnormal_lipid_homeostasis2.10204423
19MP0002138_abnormal_hepatobiliary_system1.94897347
20MP0003868_abnormal_feces_composition1.89585807
21MP0003172_abnormal_lysosome_physiology1.84987154
22MP0005319_abnormal_enzyme/_coenzyme1.81746921
23MP0001764_abnormal_homeostasis1.67777509
24MP0002089_abnormal_postnatal_growth/wei1.65580454
25MP0009697_abnormal_copulation1.65049986
26MP0000566_synostosis1.57099486
27MP0005584_abnormal_enzyme/coenzyme_acti1.56984919
28MP0003879_abnormal_hair_cell1.55522573
29MP0005451_abnormal_body_composition1.50286254
30MP0003011_delayed_dark_adaptation1.44322768
31MP0003656_abnormal_erythrocyte_physiolo1.25850380
32MP0003186_abnormal_redox_activity1.24109545
33MP0003122_maternal_imprinting1.23030482
34MP0009643_abnormal_urine_homeostasis1.21841825
35MP0000598_abnormal_liver_morphology1.17013506
36MP0005647_abnormal_sex_gland1.16690627
37MP0003705_abnormal_hypodermis_morpholog1.15720479
38MP0000604_amyloidosis1.12356451
39MP0001915_intracranial_hemorrhage1.09364480
40MP0009764_decreased_sensitivity_to1.06008361
41MP0009763_increased_sensitivity_to1.02275270
42MP0002254_reproductive_system_inflammat1.01892223
43MP0010368_abnormal_lymphatic_system0.98523769
44MP0005167_abnormal_blood-brain_barrier0.95583967
45MP0005076_abnormal_cell_differentiation0.93312461
46MP0005636_abnormal_mineral_homeostasis0.92652020
47MP0008469_abnormal_protein_level0.90349111
48MP0009642_abnormal_blood_homeostasis0.87398606
49MP0008260_abnormal_autophagy0.85080886
50MP0005408_hypopigmentation0.84858402
51MP0005409_darkened_coat_color0.81691623
52MP0006036_abnormal_mitochondrial_physio0.81001967
53MP0002249_abnormal_larynx_morphology0.80450589
54MP0005376_homeostasis/metabolism_phenot0.80411650
55MP0005084_abnormal_gallbladder_morpholo0.79007686
56MP0000858_altered_metastatic_potential0.78661895
57MP0002876_abnormal_thyroid_physiology0.78325591
58MP0009765_abnormal_xenobiotic_induced0.77784039
59MP0002078_abnormal_glucose_homeostasis0.76644778
60MP0005670_abnormal_white_adipose0.74664801
61MP0005220_abnormal_exocrine_pancreas0.72973401
62MP0002971_abnormal_brown_adipose0.70866364
63MP0004185_abnormal_adipocyte_glucose0.69181881
64MP0003690_abnormal_glial_cell0.68350778
65MP0005334_abnormal_fat_pad0.67534089
66MP0009053_abnormal_anal_canal0.66976293
67MP0001661_extended_life_span0.66813746
68MP0004130_abnormal_muscle_cell0.66263608
69MP0005535_abnormal_body_temperature0.66063056
70MP0003123_paternal_imprinting0.65470806
71MP0004264_abnormal_extraembryonic_tissu0.64919374
72MP0005266_abnormal_metabolism0.64415521
73MP0003329_amyloid_beta_deposits0.64261191
74MP0000639_abnormal_adrenal_gland0.62939738
75MP0003303_peritoneal_inflammation0.62178532
76MP0000678_abnormal_parathyroid_gland0.57902869
77MP0003183_abnormal_peptide_metabolism0.57518181
78MP0003453_abnormal_keratinocyte_physiol0.56938045
79MP0001756_abnormal_urination0.56136448
80MP0006035_abnormal_mitochondrial_morpho0.55640927
81MP0005448_abnormal_energy_balance0.54223102
82MP0005023_abnormal_wound_healing0.54164043
83MP0005464_abnormal_platelet_physiology0.53778399
84MP0003566_abnormal_cell_adhesion0.53617130
85MP0005375_adipose_tissue_phenotype0.52964823
86MP0001849_ear_inflammation0.52931993
87MP0005257_abnormal_intraocular_pressure0.51727281
88MP0000920_abnormal_myelination0.50898880
89MP0002822_catalepsy0.50172173
90MP0005395_other_phenotype0.48944998
91MP0003718_maternal_effect0.47161972
92MP0003638_abnormal_response/metabolism_0.45221146
93MP0008874_decreased_physiological_sensi0.44871749
94MP0002928_abnormal_bile_duct0.44625146
95MP0009780_abnormal_chondrocyte_physiolo0.44611671
96MP0003724_increased_susceptibility_to0.44312510
97MP0004858_abnormal_nervous_system0.44130324
98MP0009785_altered_susceptibility_to0.44105445
99MP0002136_abnormal_kidney_physiology0.43574179
100MP0002282_abnormal_trachea_morphology0.43408480
101MP0008873_increased_physiological_sensi0.42981732
102MP0003436_decreased_susceptibility_to0.42890119
103MP0003075_altered_response_to0.42806896
104MP0004381_abnormal_hair_follicle0.41988853
105MP0004782_abnormal_surfactant_physiolog0.41288484
106MP0003953_abnormal_hormone_level0.40078790
107MP0005166_decreased_susceptibility_to0.40010444
108MP0010386_abnormal_urinary_bladder0.39691267
109MP0004272_abnormal_basement_membrane0.39249431
110MP0002837_dystrophic_cardiac_calcinosis0.38996017
111MP0003115_abnormal_respiratory_system0.38940815
112MP0005248_abnormal_Harderian_gland0.38783191
113MP0008872_abnormal_physiological_respon0.36638319
114MP0009672_abnormal_birth_weight0.35409748
115MP0000579_abnormal_nail_morphology0.35406849
116MP0006082_CNS_inflammation0.35379420
117MP0005666_abnormal_adipose_tissue0.35257312
118MP0002796_impaired_skin_barrier0.33692256
119MP0009384_cardiac_valve_regurgitation0.32875858
120MP0004883_abnormal_blood_vessel0.32665324
121MP0001853_heart_inflammation0.32561039
122MP0000249_abnormal_blood_vessel0.32373257
123MP0002132_abnormal_respiratory_system0.32131071
124MP0009115_abnormal_fat_cell0.31964008
125MP0001243_abnormal_dermal_layer0.30587542
126MP0002970_abnormal_white_adipose0.30538119
127MP0002168_other_aberrant_phenotype0.28860599
128MP0000230_abnormal_systemic_arterial0.28757028
129MP0001845_abnormal_inflammatory_respons0.27881074
130MP0001881_abnormal_mammary_gland0.27431508
131MP0005164_abnormal_response_to0.26033069
132MP0002060_abnormal_skin_morphology0.22985147
133MP0000427_abnormal_hair_cycle0.22616376

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.51701420
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.39684930
3Intrahepatic cholestasis (HP:0001406)7.30320025
4Prolonged partial thromboplastin time (HP:0003645)6.69764515
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.65705468
6Hypobetalipoproteinemia (HP:0003563)6.44707908
7Xanthomatosis (HP:0000991)6.30801592
8Hyperlipoproteinemia (HP:0010980)5.64844548
9Complement deficiency (HP:0004431)5.50849041
10Joint hemorrhage (HP:0005261)4.94537365
11Hypolipoproteinemia (HP:0010981)4.85228333
12Hyperammonemia (HP:0001987)4.59722148
13Abnormality of the common coagulation pathway (HP:0010990)4.56766142
14Hyperglycinemia (HP:0002154)4.45910721
15Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.42527713
16Epidermoid cyst (HP:0200040)4.42265544
17Hypoalphalipoproteinemia (HP:0003233)4.27280974
18Abnormality of methionine metabolism (HP:0010901)4.23349480
19Ketosis (HP:0001946)4.22798893
20Abnormality of sulfur amino acid metabolism (HP:0004339)4.21946241
21Fat malabsorption (HP:0002630)4.14287899
22Abnormality of glutamine family amino acid metabolism (HP:0010902)4.08543902
23Abnormality of aspartate family amino acid metabolism (HP:0010899)4.07865593
24Abnormality of complement system (HP:0005339)4.02238711
25Hyperglycinuria (HP:0003108)3.91961314
26Abnormality of glycine metabolism (HP:0010895)3.91868646
27Abnormality of serine family amino acid metabolism (HP:0010894)3.91868646
28Hypoglycemic coma (HP:0001325)3.88178577
29Abnormality of the intrinsic pathway (HP:0010989)3.84101351
30Abnormality of pyrimidine metabolism (HP:0004353)3.83707919
31Conjugated hyperbilirubinemia (HP:0002908)3.63280096
32Hypercholesterolemia (HP:0003124)3.59136902
33Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.34393762
34Abnormality of fatty-acid metabolism (HP:0004359)3.31471898
35Hyperbilirubinemia (HP:0002904)3.31009120
36Spontaneous abortion (HP:0005268)3.18848602
37Steatorrhea (HP:0002570)3.14547360
38Abnormality of serum amino acid levels (HP:0003112)3.08886473
39Delayed CNS myelination (HP:0002188)3.07083030
40Purpura (HP:0000979)3.04846453
41Abnormality of nucleobase metabolism (HP:0010932)3.04062015
42Hypochromic microcytic anemia (HP:0004840)3.03450393
43Ketoacidosis (HP:0001993)2.98675623
44Abnormality of the Achilles tendon (HP:0005109)2.98222923
45Hepatocellular carcinoma (HP:0001402)2.96370602
46Myocardial infarction (HP:0001658)2.96276891
47Systemic lupus erythematosus (HP:0002725)2.79773812
48Metabolic acidosis (HP:0001942)2.75988947
49Skin nodule (HP:0200036)2.72887888
50Abnormality of purine metabolism (HP:0004352)2.64239064
51Lethargy (HP:0001254)2.59269004
52Vascular calcification (HP:0004934)2.58276707
53Dicarboxylic aciduria (HP:0003215)2.58059762
54Abnormality of dicarboxylic acid metabolism (HP:0010995)2.58059762
55Mucopolysacchariduria (HP:0008155)2.51250737
56Urinary glycosaminoglycan excretion (HP:0003541)2.51250737
57Acanthocytosis (HP:0001927)2.49979567
58Hypoglycemic seizures (HP:0002173)2.49685721
59Glomerulonephritis (HP:0000099)2.47854151
60Abnormal gallbladder morphology (HP:0012437)2.46777780
61Spastic diplegia (HP:0001264)2.46312467
62Recurrent gram-negative bacterial infections (HP:0005420)2.45628921
63Amyloidosis (HP:0011034)2.44020264
64Cholelithiasis (HP:0001081)2.42123254
65Mitral stenosis (HP:0001718)2.41725720
66Gout (HP:0001997)2.40737630
67Cerebral edema (HP:0002181)2.40148760
68Abnormality of polysaccharide metabolism (HP:0011012)2.38496043
69Abnormality of glycosaminoglycan metabolism (HP:0004371)2.38496043
70Abnormality of mucopolysaccharide metabolism (HP:0011020)2.38496043
71Neonatal onset (HP:0003623)2.37462922
72Cholecystitis (HP:0001082)2.33583207
73Abnormal gallbladder physiology (HP:0012438)2.33583207
74Irritability (HP:0000737)2.32270322
75Malnutrition (HP:0004395)2.31262669
76Gingival bleeding (HP:0000225)2.29446021
77Cardiovascular calcification (HP:0011915)2.28894411
78Retinal atrophy (HP:0001105)2.26333720
79Pancreatitis (HP:0001733)2.18229448
80Reticulocytosis (HP:0001923)2.17856850
81Menorrhagia (HP:0000132)2.17434892
82Esophageal varix (HP:0002040)2.15763503
83Sensorimotor neuropathy (HP:0007141)2.15189220
84Late onset (HP:0003584)2.14231961
85Thrombophlebitis (HP:0004418)2.14231082
86Increased serum ferritin (HP:0003281)2.13582115
87Enlarged kidneys (HP:0000105)2.12225073
88Brushfield spots (HP:0001088)2.11854719
89Dysostosis multiplex (HP:0000943)2.10576641
90Vomiting (HP:0002013)2.07425425
91Opisthotonus (HP:0002179)2.05647713
92Abnormality of carpal bone ossification (HP:0006257)2.05004764
93Hyperinsulinemic hypoglycemia (HP:0000825)2.04882461
94Hemorrhage of the eye (HP:0011885)2.02412858
95Abnormality of the gallbladder (HP:0005264)2.01417406
96Poikilocytosis (HP:0004447)2.00569077
97Generalized aminoaciduria (HP:0002909)1.99547566
98Bifid scrotum (HP:0000048)1.99324461
99Abnormality of iron homeostasis (HP:0011031)1.95508555
100Abnormal tarsal ossification (HP:0008369)1.95362773
101Achilles tendon contracture (HP:0001771)1.94880699
102Widely patent fontanelles and sutures (HP:0004492)1.93409634
103Rickets (HP:0002748)1.91857988
104Abnormality of transition element cation homeostasis (HP:0011030)1.91731116
105Pulmonary embolism (HP:0002204)1.91122707
106Hypertriglyceridemia (HP:0002155)1.89074953
107Pathologic fracture (HP:0002756)1.88148851
108Hypophosphatemia (HP:0002148)1.86828637
109Hypophosphatemic rickets (HP:0004912)1.85943998
110Renal cortical cysts (HP:0000803)1.85541109
111Abnormal cartilage morphology (HP:0002763)1.83939820
112Hydroxyprolinuria (HP:0003080)1.82070328
113Abnormality of proline metabolism (HP:0010907)1.82070328
114Elevated alkaline phosphatase (HP:0003155)1.81891621
115Status epilepticus (HP:0002133)1.81776310
116Vaginal fistula (HP:0004320)1.80370374
117Elevated hepatic transaminases (HP:0002910)1.79984556
118Impaired platelet aggregation (HP:0003540)1.79639268
119Abnormal platelet function (HP:0011869)1.79639268
120Abnormal enzyme/coenzyme activity (HP:0012379)1.79109735
121Back pain (HP:0003418)1.78523019
122Abnormality of alkaline phosphatase activity (HP:0004379)1.78065471
123Alkalosis (HP:0001948)1.76571287
124Nephritis (HP:0000123)1.76183810
125Abnormality of vitamin metabolism (HP:0100508)1.73460434
126Hyperglycemia (HP:0003074)1.72594198
127Gangrene (HP:0100758)1.69639303
128Vertebral compression fractures (HP:0002953)1.69177366
129Polygenic inheritance (HP:0010982)1.66202962
130Asymmetry of the thorax (HP:0001555)1.65294508
131Lymphangioma (HP:0100764)1.64660153
132Joint swelling (HP:0001386)1.64349595
133Thin bony cortex (HP:0002753)1.64020942
134Neurofibrillary tangles (HP:0002185)1.62961874
135Epistaxis (HP:0000421)1.62781213
136Ulnar bowing (HP:0003031)1.60442123
137Abnormal delivery (HP:0001787)1.60119454
138Increased serum pyruvate (HP:0003542)1.59625734

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.24290856
2FGFR44.75234061
3ERN14.59520292
4SIK14.57289490
5TAOK33.21924818
6ERBB42.93727229
7INSRR2.85690598
8MAP2K42.32104489
9MST1R2.10951819
10PKN22.08788486
11EPHA21.94089269
12SMG11.89022883
13MAPK111.88774674
14EEF2K1.87645738
15PIK3CG1.87439374
16FLT31.82442140
17TRIB31.75666983
18PRPF4B1.74159083
19TYK21.72354716
20DAPK21.59493706
21CDK121.55092933
22LATS11.53969434
23DDR21.53056980
24PDGFRA1.51608364
25PTK61.49975387
26ABL21.47358289
27TYRO31.39094239
28NEK91.34161442
29KDR1.31758761
30FGFR21.28936384
31NTRK31.25577166
32FRK1.25032317
33JAK21.21803960
34MAP3K71.20513254
35PINK11.11126634
36GRK61.11063776
37PRKAA21.10397555
38TAOK11.07792980
39SIK21.06580735
40MAP2K31.05444892
41TBK11.03814925
42ERBB21.01776455
43JAK11.00758913
44CDC42BPA0.99165117
45MAP3K140.98241782
46WNK40.97543721
47MAP3K100.96276573
48MAPK40.96132985
49MAPK150.93906039
50PRKCZ0.92975197
51NME20.91148760
52PIM20.89486479
53EPHB10.86890213
54MAP3K110.85582412
55MET0.84402823
56MAP3K30.84034898
57EPHA30.81116829
58CDK60.80816512
59MAPK120.80777706
60STK38L0.79611015
61GRK10.76939585
62MATK0.76838468
63TIE10.76432181
64PRKACG0.76391025
65CAMK2G0.75083383
66DYRK1B0.72320291
67MAP3K20.71577771
68FGR0.71495795
69KSR20.69214237
70CSK0.67783685
71GSK3A0.66516746
72MAP2K60.66221001
73IRAK30.64269481
74FGFR10.63232344
75MARK20.62362988
76CAMK1D0.62212378
77PRKAA10.61840920
78ARAF0.59149660
79PDK20.59067755
80MAP3K130.57996734
81PTK20.57690724
82TGFBR20.57628964
83BLK0.57549285
84RIPK10.56520986
85MAPK70.56283133
86SGK30.56277253
87FGFR30.53585973
88CSF1R0.53140394
89IKBKE0.52432224
90PRKCQ0.51729794
91TAOK20.51242153
92LMTK20.51017497
93RPS6KA20.50960468
94PDPK10.50806662
95EPHA40.50745262
96PRKD20.50713316
97MAPKAPK30.50620012
98ZAP700.50148976
99CHUK0.48833220
100CSNK1G10.46692888
101MAP2K10.44805923
102PRKCG0.43660955
103PKN10.43304345
104IGF1R0.42030194
105CDK40.41640890
106MAP3K50.41617283
107PAK40.40713956
108ICK0.40702722
109MAP4K10.40569715
110RPS6KL10.39891920
111RPS6KC10.39891920
112SGK20.39272871
113RET0.39268586
114TESK20.38517287
115PRKG20.37377919
116AKT20.36708802
117MAP3K60.35452143
118MTOR0.34964530
119CAMK40.34931665
120PBK0.34436266
121CDK70.33767088
122CDK90.32012179
123EGFR0.31807370
124PDK10.29215344
125SRC0.29202744
126IRAK10.29197961
127MAP3K10.28892182
128BRAF0.27518477
129SGK4940.27109683
130SGK2230.27109683
131LATS20.26888758
132CSNK1G20.26135107
133PRKCA0.25741350
134CSNK1G30.25244333
135PIK3CA0.24865828
136IRAK20.22667669
137MAP2K20.21844673
138BMX0.21551281
139PAK30.19807285
140ABL10.19441221
141MAPK30.19337376

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.57537570
2Nitrogen metabolism_Homo sapiens_hsa009103.51528006
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.34563545
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.33050444
5Arginine biosynthesis_Homo sapiens_hsa002203.07844568
6Complement and coagulation cascades_Homo sapiens_hsa046102.84293060
7Tryptophan metabolism_Homo sapiens_hsa003802.69073517
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.66695062
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.65276952
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.57096598
11Fatty acid degradation_Homo sapiens_hsa000712.47803280
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.38215672
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.22361970
14Butanoate metabolism_Homo sapiens_hsa006502.16475130
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.14145761
16Peroxisome_Homo sapiens_hsa041462.07777179
17Chemical carcinogenesis_Homo sapiens_hsa052041.95921107
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.92888851
19Steroid hormone biosynthesis_Homo sapiens_hsa001401.92512617
20Histidine metabolism_Homo sapiens_hsa003401.90931055
21Propanoate metabolism_Homo sapiens_hsa006401.90729205
22PPAR signaling pathway_Homo sapiens_hsa033201.85772043
23Other glycan degradation_Homo sapiens_hsa005111.85353869
24Staphylococcus aureus infection_Homo sapiens_hsa051501.79757185
25Fatty acid metabolism_Homo sapiens_hsa012121.79118334
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.76880908
27Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.72828787
28Retinol metabolism_Homo sapiens_hsa008301.70480842
29beta-Alanine metabolism_Homo sapiens_hsa004101.69842256
30Caffeine metabolism_Homo sapiens_hsa002321.68462751
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65019296
32Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.64432637
33Selenocompound metabolism_Homo sapiens_hsa004501.57560838
34Phenylalanine metabolism_Homo sapiens_hsa003601.55877975
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.52811437
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.51018179
37Bile secretion_Homo sapiens_hsa049761.48655389
38Tyrosine metabolism_Homo sapiens_hsa003501.45683847
39Sulfur metabolism_Homo sapiens_hsa009201.36562445
40Pyruvate metabolism_Homo sapiens_hsa006201.34947394
41Fatty acid elongation_Homo sapiens_hsa000621.33613035
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.31534112
43Starch and sucrose metabolism_Homo sapiens_hsa005001.27027576
44Folate biosynthesis_Homo sapiens_hsa007901.24095448
45Steroid biosynthesis_Homo sapiens_hsa001001.20437856
46Biosynthesis of amino acids_Homo sapiens_hsa012301.19685995
47Fat digestion and absorption_Homo sapiens_hsa049751.19587901
48ABC transporters_Homo sapiens_hsa020101.18919407
49Carbon metabolism_Homo sapiens_hsa012001.11727922
50Maturity onset diabetes of the young_Homo sapiens_hsa049501.05145454
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02649122
52Vitamin B6 metabolism_Homo sapiens_hsa007501.01967880
53Cyanoamino acid metabolism_Homo sapiens_hsa004601.01704814
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99354509
55Sulfur relay system_Homo sapiens_hsa041220.97865121
56Arginine and proline metabolism_Homo sapiens_hsa003300.96727637
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.89748726
58Vitamin digestion and absorption_Homo sapiens_hsa049770.86503031
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.82457580
60Lysine degradation_Homo sapiens_hsa003100.79818072
61One carbon pool by folate_Homo sapiens_hsa006700.79378206
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.69094318
63Glutathione metabolism_Homo sapiens_hsa004800.66562535
64Glycerolipid metabolism_Homo sapiens_hsa005610.66203370
65Pertussis_Homo sapiens_hsa051330.56722025
66Pentose phosphate pathway_Homo sapiens_hsa000300.56042067
67Fatty acid biosynthesis_Homo sapiens_hsa000610.51662515
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.46640951
69Metabolic pathways_Homo sapiens_hsa011000.46081374
70Sphingolipid metabolism_Homo sapiens_hsa006000.44786427
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.44171669
72Prion diseases_Homo sapiens_hsa050200.40077938
73Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37240746
74Mineral absorption_Homo sapiens_hsa049780.35101050
75Lysosome_Homo sapiens_hsa041420.31777555
76Galactose metabolism_Homo sapiens_hsa000520.26965789
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25987756
78Fructose and mannose metabolism_Homo sapiens_hsa000510.22971821
79Linoleic acid metabolism_Homo sapiens_hsa005910.22505907
80Insulin resistance_Homo sapiens_hsa049310.21947255
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.20240488
82Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19983798
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.15779127
84N-Glycan biosynthesis_Homo sapiens_hsa005100.12556197
85Glucagon signaling pathway_Homo sapiens_hsa049220.08678331
86AMPK signaling pathway_Homo sapiens_hsa041520.00654529
87Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2472915
88Ether lipid metabolism_Homo sapiens_hsa00565-0.2413046
89Bladder cancer_Homo sapiens_hsa05219-0.2344883
90Amoebiasis_Homo sapiens_hsa05146-0.2331391
91Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2234928
92Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1926131
93Renin-angiotensin system_Homo sapiens_hsa04614-0.1921538
94Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1907706
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1862636
96Hepatitis C_Homo sapiens_hsa05160-0.1781220
97Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1624601
98Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1606338
99Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1527483
100Regulation of autophagy_Homo sapiens_hsa04140-0.1462391
101African trypanosomiasis_Homo sapiens_hsa05143-0.1268900
102Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1223682
103Insulin signaling pathway_Homo sapiens_hsa04910-0.1029780
104VEGF signaling pathway_Homo sapiens_hsa04370-0.0858619
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0802151
106Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0724543
107Acute myeloid leukemia_Homo sapiens_hsa05221-0.0619105
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0596656
109Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0423366

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