GLTSCR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1N-terminal protein amino acid acetylation (GO:0006474)5.14492411
2positive regulation of gamma-delta T cell activation (GO:0046645)4.94491138
3negative regulation of cardiac muscle hypertrophy (GO:0010614)4.73456263
4negative regulation of glycogen biosynthetic process (GO:0045719)4.67413134
5membrane tubulation (GO:0097320)4.52076811
6negative regulation of cAMP-mediated signaling (GO:0043951)4.33680211
7regulation of energy homeostasis (GO:2000505)4.22001190
8negative regulation of muscle hypertrophy (GO:0014741)4.18359718
9positive thymic T cell selection (GO:0045059)4.10522581
10negative regulation of cell killing (GO:0031342)3.98694040
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.98694040
12regulation of gamma-delta T cell differentiation (GO:0045586)3.94052155
13B cell receptor signaling pathway (GO:0050853)3.89482591
14regulation of gamma-delta T cell activation (GO:0046643)3.83479334
15positive regulation of gene expression, epigenetic (GO:0045815)3.80249220
16negative regulation of glycogen metabolic process (GO:0070874)3.78909512
17positive regulation of histone deacetylation (GO:0031065)3.74899072
18regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00433.70577650
19histone H3-K4 methylation (GO:0051568)3.67735068
20negative regulation of erythrocyte differentiation (GO:0045647)3.66950623
21positive T cell selection (GO:0043368)3.56394625
22intracellular estrogen receptor signaling pathway (GO:0030520)3.43556406
23histone H3-K36 demethylation (GO:0070544)3.39209225
24negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.37579582
25interleukin-6-mediated signaling pathway (GO:0070102)3.37076219
26T cell selection (GO:0045058)3.35350981
27nucleosome disassembly (GO:0006337)3.34673855
28protein-DNA complex disassembly (GO:0032986)3.34673855
29positive regulation of T cell apoptotic process (GO:0070234)3.33123734
30tolerance induction (GO:0002507)3.32919290
31histone H3-K4 trimethylation (GO:0080182)3.32363388
32positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.30476259
33positive regulation by host of viral transcription (GO:0043923)3.24362301
34positive regulation of CREB transcription factor activity (GO:0032793)3.24116465
35thymic T cell selection (GO:0045061)3.23908264
36epithelial cell fate commitment (GO:0072148)3.16482936
37pre-miRNA processing (GO:0031054)3.15675611
38positive regulation of granulocyte differentiation (GO:0030854)3.08049399
39megakaryocyte development (GO:0035855)3.07438693
40negative T cell selection (GO:0043383)3.06259066
41negative thymic T cell selection (GO:0045060)3.04145122
42venous blood vessel morphogenesis (GO:0048845)3.03637111
43positive regulation of B cell differentiation (GO:0045579)3.02093738
44regulation of B cell differentiation (GO:0045577)3.01419477
45lymph node development (GO:0048535)2.96893474
46negative regulation of histone methylation (GO:0031061)2.96677409
47mannose metabolic process (GO:0006013)2.96459086
48V(D)J recombination (GO:0033151)2.94345556
49protein localization to endosome (GO:0036010)2.93689778
50regulation of histone deacetylation (GO:0031063)2.91816989
51regulation of interleukin-12 biosynthetic process (GO:0045075)2.87056938
52mucosal-associated lymphoid tissue development (GO:0048537)2.87000160
53Peyers patch development (GO:0048541)2.87000160
54regulation of NFAT protein import into nucleus (GO:0051532)2.84721263
55regulation of B cell receptor signaling pathway (GO:0050855)2.84602514
56regulation of oxidative stress-induced neuron death (GO:1903203)2.82452407
57regulation of granulocyte differentiation (GO:0030852)2.80371681
58histone lysine methylation (GO:0034968)2.79632916
59negative regulation of T cell mediated immunity (GO:0002710)2.78854169
60positive regulation of lymphocyte apoptotic process (GO:0070230)2.78296949
61positive regulation of protein deacetylation (GO:0090312)2.77469747
62positive regulation by symbiont of host defense response (GO:0052509)2.75940464
63modulation by symbiont of host defense response (GO:0052031)2.75940464
64modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.75940464
65modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.75940464
66positive regulation by organism of defense response of other organism involved in symbiotic interact2.75940464
67modulation by symbiont of host immune response (GO:0052553)2.75940464
68positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.71798238
69regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.71697912
70positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.71697912
71antigen receptor-mediated signaling pathway (GO:0050851)2.66630839
72positive regulation of protein homooligomerization (GO:0032464)2.64482413
73DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.64218314
74negative regulation of glial cell proliferation (GO:0060253)2.63429253
75leukocyte aggregation (GO:0070486)2.62529017
76regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.62085944
77positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.62085944
78embryonic hemopoiesis (GO:0035162)2.61778098
79interferon-gamma production (GO:0032609)2.61034727
80cell migration involved in heart development (GO:0060973)2.60705725
81forebrain morphogenesis (GO:0048853)2.60168750
82natural killer cell differentiation (GO:0001779)2.59649311
83positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.58843164
84antigen processing and presentation of endogenous antigen (GO:0019883)2.58658995
85cellular response to interleukin-6 (GO:0071354)2.58551747
86positive regulation of fatty acid beta-oxidation (GO:0032000)2.57646755
87negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.56133798
88lens fiber cell development (GO:0070307)2.55680912
89positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.55224788
90positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.53558236
91membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.51551369
92cellular response to zinc ion (GO:0071294)2.51246655
93cell proliferation in forebrain (GO:0021846)2.50550268
94negative regulation of granulocyte differentiation (GO:0030853)2.49900319
95DNA demethylation (GO:0080111)2.48908194
96endoderm formation (GO:0001706)2.48568570
97histone H4-K12 acetylation (GO:0043983)2.48444705
98cell-cell junction maintenance (GO:0045217)2.46472553
99positive regulation of mRNA catabolic process (GO:0061014)2.46425618
100positive regulation of natural killer cell differentiation (GO:0032825)2.46347292
101regulation of respiratory gaseous exchange (GO:0043576)2.45847888
102positive regulation of interleukin-4 production (GO:0032753)2.45608477
103B cell homeostasis (GO:0001782)2.45093439
104positive regulation of Rap GTPase activity (GO:0032854)2.44372744
105DNA damage response, signal transduction resulting in transcription (GO:0042772)2.44314904
106regulation of mRNA catabolic process (GO:0061013)2.44019632
107response to muramyl dipeptide (GO:0032495)2.43802947
108histone H4-K16 acetylation (GO:0043984)2.43241452
109peptidyl-lysine trimethylation (GO:0018023)2.42715607
110lymphocyte homeostasis (GO:0002260)2.42157303
111negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.42041214
112negative regulation of translation, ncRNA-mediated (GO:0040033)2.42041214
113regulation of translation, ncRNA-mediated (GO:0045974)2.42041214
114regulation of chromatin binding (GO:0035561)2.41838069
115barbed-end actin filament capping (GO:0051016)2.41200029
116T cell homeostasis (GO:0043029)2.40763860
117regulation of posttranscriptional gene silencing (GO:0060147)2.39955605
118regulation of gene silencing by miRNA (GO:0060964)2.39955605
119regulation of gene silencing by RNA (GO:0060966)2.39955605
120RNA localization (GO:0006403)2.39922206
121histone methylation (GO:0016571)2.39579818
122modulation by virus of host process (GO:0019054)2.39195966
123negative regulation of interleukin-6 production (GO:0032715)2.38767887
124dosage compensation (GO:0007549)2.38388080
125response to interleukin-15 (GO:0070672)2.38080810
126positive regulation of T cell differentiation in thymus (GO:0033089)2.36133485
127negative regulation of phagocytosis (GO:0050765)2.35825973
128T cell receptor signaling pathway (GO:0050852)2.35282000
129antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.35163806
130antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.35163806
131regulation of erythrocyte differentiation (GO:0045646)2.35079883
132regulation of T cell tolerance induction (GO:0002664)2.35014783
133T cell migration (GO:0072678)2.34659349
134germinal center formation (GO:0002467)2.34413833
135histone H3 acetylation (GO:0043966)2.34029593
136regulation of protein deacetylation (GO:0090311)2.33303352
137stress granule assembly (GO:0034063)2.32964089
138positive regulation of tolerance induction (GO:0002645)2.32246395
139coronary vasculature morphogenesis (GO:0060977)2.32209533
140regulation of extracellular matrix disassembly (GO:0010715)2.31633800
141apoptotic process involved in morphogenesis (GO:0060561)2.31263946
142regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.30786803
143negative regulation of RNA splicing (GO:0033119)2.30771741
144B cell proliferation (GO:0042100)2.28582353
145response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.27272708
146response to host (GO:0075136)2.27272708
147response to host defenses (GO:0052200)2.27272708
148embryonic camera-type eye development (GO:0031076)2.26729922
149positive regulation of RNA splicing (GO:0033120)2.26076084
150positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.25942659
151glucocorticoid receptor signaling pathway (GO:0042921)2.25562276
152aorta morphogenesis (GO:0035909)2.24831033
153regulation of MHC class I biosynthetic process (GO:0045343)2.24294104
154outflow tract septum morphogenesis (GO:0003148)2.23794560
155regulation of interleukin-4 production (GO:0032673)2.23350393
156regulation of dendritic cell antigen processing and presentation (GO:0002604)2.23079363
157response to laminar fluid shear stress (GO:0034616)2.22382176
158atrioventricular valve morphogenesis (GO:0003181)2.19802463
159positive regulation of protein kinase C signaling (GO:0090037)2.16339880
160negative regulation of interleukin-1 production (GO:0032692)2.15607872
161regulation of interleukin-2 biosynthetic process (GO:0045076)2.14572630
162activated T cell proliferation (GO:0050798)2.14413303
163cell migration involved in gastrulation (GO:0042074)2.14302723
164CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.13530148
165positive regulation of humoral immune response (GO:0002922)2.13403217

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_22102868_ChIP-Seq_BL_Human4.94044258
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.79808153
3VDR_21846776_ChIP-Seq_THP-1_Human3.76278997
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.61458219
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.47412096
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.45787114
7EZH2_22144423_ChIP-Seq_EOC_Human3.27872692
8KDM2B_26808549_Chip-Seq_SUP-B15_Human3.13915541
9TCF7_22412390_ChIP-Seq_EML_Mouse3.07096482
10TP63_19390658_ChIP-ChIP_HaCaT_Human3.01608513
11* KDM2B_26808549_Chip-Seq_DND41_Human2.93954680
12E2F7_22180533_ChIP-Seq_HELA_Human2.91484088
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.84721386
14SCL_19346495_ChIP-Seq_HPC-7_Human2.79596997
15* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.63045269
16VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.55820956
17MAF_26560356_Chip-Seq_TH1_Human2.54453907
18KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.54303049
19E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.46435769
20IRF8_22096565_ChIP-ChIP_GC-B_Human2.39130611
21UTX_26944678_Chip-Seq_JUKART_Human2.39095630
22MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.35101580
23FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.26410475
24RUNX_20019798_ChIP-Seq_JUKART_Human2.25539245
25EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.23929768
26VDR_24763502_ChIP-Seq_THP-1_Human2.20078058
27ELK3_25401928_ChIP-Seq_HUVEC_Human2.15769570
28CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.05991500
29CIITA_25753668_ChIP-Seq_RAJI_Human2.05659525
30ZFP281_27345836_Chip-Seq_ESCs_Mouse1.96543731
31* KDM2B_26808549_Chip-Seq_JURKAT_Human1.96024494
32SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.90488569
33* SPI1_23127762_ChIP-Seq_K562_Human1.89957733
34ERG_21242973_ChIP-ChIP_JURKAT_Human1.85180479
35LXR_22292898_ChIP-Seq_THP-1_Human1.83750084
36EZH2_27294783_Chip-Seq_ESCs_Mouse1.83748447
37MYB_26560356_Chip-Seq_TH2_Human1.82575091
38SUZ12_27294783_Chip-Seq_ESCs_Mouse1.80872860
39MYB_26560356_Chip-Seq_TH1_Human1.79598521
40JARID2_20075857_ChIP-Seq_MESCs_Mouse1.76167149
41JARID2_20064375_ChIP-Seq_MESCs_Mouse1.74567548
42* KDM2B_26808549_Chip-Seq_K562_Human1.73611983
43EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.69489290
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.65661205
45IRF8_21731497_ChIP-ChIP_J774_Mouse1.64480228
46RNF2_27304074_Chip-Seq_ESCs_Mouse1.63137126
47MAF_26560356_Chip-Seq_TH2_Human1.62956907
48CTCF_27219007_Chip-Seq_Bcells_Human1.62786296
49ZFP281_18757296_ChIP-ChIP_E14_Mouse1.62617346
50IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.62524929
51THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.62450687
52EZH2_27304074_Chip-Seq_ESCs_Mouse1.57966435
53* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.57604343
54SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.57133330
55TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.57105384
56* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.56755275
57SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56456045
58BCL6_27268052_Chip-Seq_Bcells_Human1.55022542
59RUNX1_22412390_ChIP-Seq_EML_Mouse1.52048677
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.51145105
61SMC4_20622854_ChIP-Seq_HELA_Human1.51133008
62KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.49696599
63KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.49696599
64KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.49696599
65BRD4_27068464_Chip-Seq_AML-cells_Mouse1.48283740
66OCT4_19829295_ChIP-Seq_ESCs_Human1.48095283
67IRF8_27001747_Chip-Seq_BMDM_Mouse1.46459290
68GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.43642552
69GATA1_19941827_ChIP-Seq_MEL_Mouse1.43266988
70RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.42613264
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.42232971
72TP53_20018659_ChIP-ChIP_R1E_Mouse1.41596634
73BCOR_27268052_Chip-Seq_Bcells_Human1.41356776
74SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.41209280
75STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.40440240
76WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.38832786
77EED_16625203_ChIP-ChIP_MESCs_Mouse1.36454202
78EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.35935161
79IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.32637157
80RNF2_18974828_ChIP-Seq_MESCs_Mouse1.31127720
81EZH2_18974828_ChIP-Seq_MESCs_Mouse1.31127720
82TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.29139955
83NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.28312747
84MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.27982673
85SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.27428556
86IKZF1_21737484_ChIP-ChIP_HCT116_Human1.24235054
87E2F1_20622854_ChIP-Seq_HELA_Human1.23175370
88* SA1_27219007_Chip-Seq_Bcells_Human1.21684043
89RING1B_27294783_Chip-Seq_ESCs_Mouse1.18786167
90PHF8_20622854_ChIP-Seq_HELA_Human1.18253999
91MTF2_20144788_ChIP-Seq_MESCs_Mouse1.16349875
92SPI1_23547873_ChIP-Seq_NB4_Human1.16097128
93NCOR1_26117541_ChIP-Seq_K562_Human1.15207938
94P300_27058665_Chip-Seq_ZR-75-30cells_Human1.14717072
95NFIB_24661679_ChIP-Seq_LUNG_Mouse1.13735326
96TET1_21451524_ChIP-Seq_MESCs_Mouse1.12694711
97DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11599670
98PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.11167314
99TP63_22573176_ChIP-Seq_HFKS_Human1.11167287
100* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.11004244
101RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.10454419
102ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.10140494
103NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09863958
104STAT4_19710469_ChIP-ChIP_TH1__Mouse1.09258915
105VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.07935192
106MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.07044424
107* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.06181607
108CTCF_26484167_Chip-Seq_Bcells_Mouse1.06161465
109P68_20966046_ChIP-Seq_HELA_Human1.04846749
110SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.04573987
111MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.04110456
112* DROSHA_22980978_ChIP-Seq_HELA_Human1.03637798
113CTCF_21964334_ChIP-Seq_BJAB-B_Human1.03607758
114TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03555337
115SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.03470780
116SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.03094150
117KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.03016881
118* RACK7_27058665_Chip-Seq_MCF-7_Human1.01789936
119* TP53_22127205_ChIP-Seq_IMR90_Human1.01215517
120SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00120941
121RARB_24833708_ChIP-Seq_LIVER_Mouse0.99455124
122SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.99305762
123CTCF_20526341_ChIP-Seq_ESCs_Human0.99026044
124RING1B_27294783_Chip-Seq_NPCs_Mouse0.98307995
125ELF1_20517297_ChIP-Seq_JURKAT_Human0.95256993
126CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.95238871
127NOTCH1_21737748_ChIP-Seq_TLL_Human0.94067205
128GATA3_27048872_Chip-Seq_THYMUS_Human0.94015092
129PKCTHETA_26484144_Chip-Seq_BREAST_Human0.93535628
130GATA1_22383799_ChIP-Seq_G1ME_Mouse0.93316134
131PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92688954
132CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.92016906
133GATA1_19941826_ChIP-Seq_K562_Human0.91972366
134MYB_21317192_ChIP-Seq_ERMYB_Mouse0.90340360
135BP1_19119308_ChIP-ChIP_Hs578T_Human0.90197924
136OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.89466703
137* SA1_27219007_Chip-Seq_ERYTHROID_Human0.87975714
138UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.87907890
139SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.85560168
140SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.84894924
141CREB1_26743006_Chip-Seq_LNCaP_Human0.83962961
142ISL1_27105846_Chip-Seq_CPCs_Mouse0.83008086
143GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82693934
144RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.82616424
145RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.82512556
146TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.81954551
147* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80579271
148FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.79909811

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006054_spinal_hemorrhage3.60564708
2MP0003279_aneurysm3.15513218
3MP0000569_abnormal_digit_pigmentation3.12873567
4MP0009278_abnormal_bone_marrow2.97784752
5MP0000566_synostosis2.88291937
6MP0003303_peritoneal_inflammation2.76830691
7MP0000685_abnormal_immune_system2.75205566
8MP0005623_abnormal_meninges_morphology2.72629731
9MP0001800_abnormal_humoral_immune2.67973493
10MP0001348_abnormal_lacrimal_gland2.66655644
11MP0002396_abnormal_hematopoietic_system2.65536039
12MP0010030_abnormal_orbit_morphology2.65363677
13MP0005387_immune_system_phenotype2.61670810
14MP0001790_abnormal_immune_system2.61670810
15MP0000678_abnormal_parathyroid_gland2.46787607
16MP0008961_abnormal_basal_metabolism2.42642275
17MP0001835_abnormal_antigen_presentation2.26142667
18MP0002163_abnormal_gland_morphology2.25883586
19MP0001986_abnormal_taste_sensitivity2.25754700
20MP0003763_abnormal_thymus_physiology2.24551429
21MP0002398_abnormal_bone_marrow2.22292617
22MP0005671_abnormal_response_to2.19957300
23MP0002452_abnormal_antigen_presenting2.06408477
24MP0005076_abnormal_cell_differentiation2.03874017
25MP0004808_abnormal_hematopoietic_stem2.01516687
26MP0000703_abnormal_thymus_morphology1.98307631
27MP0001873_stomach_inflammation1.96707972
28MP0002837_dystrophic_cardiac_calcinosis1.92895933
29MP0002254_reproductive_system_inflammat1.91214005
30MP0004130_abnormal_muscle_cell1.89377773
31MP0002420_abnormal_adaptive_immunity1.89106158
32MP0001819_abnormal_immune_cell1.86673779
33MP0002723_abnormal_immune_serum1.84166467
34MP0003300_gastrointestinal_ulcer1.83663684
35MP0000716_abnormal_immune_system1.81508762
36MP0002653_abnormal_ependyma_morphology1.76294070
37MP0005000_abnormal_immune_tolerance1.71529791
38MP0005423_abnormal_somatic_nervous1.69345665
39MP0004145_abnormal_muscle_electrophysio1.67608727
40MP0002722_abnormal_immune_system1.66447646
41MP0000689_abnormal_spleen_morphology1.63696757
42MP0003183_abnormal_peptide_metabolism1.62285618
43MP0005174_abnormal_tail_pigmentation1.58592781
44MP0003436_decreased_susceptibility_to1.58425990
45MP0002429_abnormal_blood_cell1.51857300
46MP0005397_hematopoietic_system_phenotyp1.50282158
47MP0001545_abnormal_hematopoietic_system1.50282158
48MP0004858_abnormal_nervous_system1.47247594
49MP0004084_abnormal_cardiac_muscle1.47073090
50MP0002405_respiratory_system_inflammati1.45592303
51MP0000767_abnormal_smooth_muscle1.45357590
52MP0004510_myositis1.44395578
53MP0003283_abnormal_digestive_organ1.41448591
54MP0000049_abnormal_middle_ear1.40614718
55MP0000490_abnormal_crypts_of1.40511463
56MP0005377_hearing/vestibular/ear_phenot1.38118726
57MP0003878_abnormal_ear_physiology1.38118726
58MP0000733_abnormal_muscle_development1.35589769
59MP0001346_abnormal_lacrimal_gland1.33805509
60MP0002138_abnormal_hepatobiliary_system1.32992984
61MP0002166_altered_tumor_susceptibility1.32539638
62MP0001915_intracranial_hemorrhage1.28378340
63MP0003724_increased_susceptibility_to1.24060669
64MP0003091_abnormal_cell_migration1.22453193
65MP0010155_abnormal_intestine_physiology1.21631962
66MP0005025_abnormal_response_to1.20980532
67MP0003111_abnormal_nucleus_morphology1.19677407
68MP0002693_abnormal_pancreas_physiology1.18956638
69MP0004381_abnormal_hair_follicle1.16139693
70MP0003866_abnormal_defecation1.15666314
71MP0003077_abnormal_cell_cycle1.12405952
72MP0001502_abnormal_circadian_rhythm1.11958199
73MP0002933_joint_inflammation1.10978153
74MP0005257_abnormal_intraocular_pressure1.10548027
75MP0002089_abnormal_postnatal_growth/wei1.10076156
76MP0008995_early_reproductive_senescence1.09095108
77MP0001501_abnormal_sleep_pattern1.08646941
78MP0005448_abnormal_energy_balance1.08286902
79MP0003705_abnormal_hypodermis_morpholog1.07021357
80MP0002249_abnormal_larynx_morphology1.06818681
81MP0002116_abnormal_craniofacial_bone1.05043350
82MP0002419_abnormal_innate_immunity1.04866770
83MP0004885_abnormal_endolymph1.04041721
84MP0009333_abnormal_splenocyte_physiolog1.03853668
85MP0010352_gastrointestinal_tract_polyps1.03725773
86MP0003787_abnormal_imprinting1.02391070
87MP0004947_skin_inflammation1.02386673
88MP0005310_abnormal_salivary_gland0.99890779
89MP0002822_catalepsy0.99744212
90MP0003942_abnormal_urinary_system0.99701828
91MP0004133_heterotaxia0.99573061
92MP0008057_abnormal_DNA_replication0.97533507
93MP0002925_abnormal_cardiovascular_devel0.96091676
94MP0005645_abnormal_hypothalamus_physiol0.95843094
95MP0004185_abnormal_adipocyte_glucose0.95582475
96MP0002277_abnormal_respiratory_mucosa0.95273445
97MP0000465_gastrointestinal_hemorrhage0.93875290
98MP0001849_ear_inflammation0.92976255
99MP0005464_abnormal_platelet_physiology0.92029276
100MP0000470_abnormal_stomach_morphology0.91147518
101MP0002733_abnormal_thermal_nociception0.91107094
102MP0000350_abnormal_cell_proliferation0.90575624
103MP0002006_tumorigenesis0.90257190
104MP0001968_abnormal_touch/_nociception0.89361806
105MP0003172_abnormal_lysosome_physiology0.88437752
106MP0003938_abnormal_ear_development0.86854732
107MP0003890_abnormal_embryonic-extraembry0.86135444
108MP0003828_pulmonary_edema0.85004153
109MP0003119_abnormal_digestive_system0.84317057
110MP0004742_abnormal_vestibular_system0.84230820
111MP0005220_abnormal_exocrine_pancreas0.84118715
112MP0002735_abnormal_chemical_nociception0.82480389
113MP0006082_CNS_inflammation0.82411550
114MP0004134_abnormal_chest_morphology0.81951091
115MP0003121_genomic_imprinting0.81836834
116MP0002019_abnormal_tumor_incidence0.81272199
117MP0005379_endocrine/exocrine_gland_phen0.80560340
118MP0009780_abnormal_chondrocyte_physiolo0.80029089
119MP0003984_embryonic_growth_retardation0.79755428
120MP0000015_abnormal_ear_pigmentation0.79091432
121MP0001663_abnormal_digestive_system0.79079044
122MP0006292_abnormal_olfactory_placode0.77940624
123MP0002088_abnormal_embryonic_growth/wei0.77529557
124MP0002928_abnormal_bile_duct0.77507627
125MP0003879_abnormal_hair_cell0.77044669
126MP0002085_abnormal_embryonic_tissue0.76027162
127MP0005670_abnormal_white_adipose0.76013622
128MP0010094_abnormal_chromosome_stability0.75997644
129MP0002084_abnormal_developmental_patter0.75788717
130MP0000371_diluted_coat_color0.74889099
131MP0001845_abnormal_inflammatory_respons0.74685759
132MP0002932_abnormal_joint_morphology0.73670093
133MP0010630_abnormal_cardiac_muscle0.73649953
134MP0005380_embryogenesis_phenotype0.73084269
135MP0001672_abnormal_embryogenesis/_devel0.73084269
136MP0000003_abnormal_adipose_tissue0.71700152
137MP0000026_abnormal_inner_ear0.71511052
138MP0005375_adipose_tissue_phenotype0.70916367
139MP0002075_abnormal_coat/hair_pigmentati0.70851353
140MP0002751_abnormal_autonomic_nervous0.70084835
141MP0003935_abnormal_craniofacial_develop0.69741441
142MP0004036_abnormal_muscle_relaxation0.69563749
143MP0000428_abnormal_craniofacial_morphol0.69468958
144MP0000266_abnormal_heart_morphology0.68973320
145MP0002092_abnormal_eye_morphology0.68860346
146MP0001784_abnormal_fluid_regulation0.68857129
147MP0008770_decreased_survivor_rate0.68177268
148MP0000313_abnormal_cell_death0.67920662
149MP0001533_abnormal_skeleton_physiology0.67903208
150MP0008569_lethality_at_weaning0.67879092
151MP0003137_abnormal_impulse_conducting0.67778403
152MP0009785_altered_susceptibility_to0.67136991
153MP0004484_altered_response_of0.66478984
154MP0004859_abnormal_synaptic_plasticity0.65950125
155MP0002998_abnormal_bone_remodeling0.65829966
156MP0002148_abnormal_hypersensitivity_rea0.65618438
157MP0003880_abnormal_central_pattern0.65493140
158MP0001919_abnormal_reproductive_system0.62235088
159MP0003635_abnormal_synaptic_transmissio0.61637272
160MP0009250_abnormal_appendicular_skeleto0.60963339

Predicted human phenotypes

RankGene SetZ-score
1Chronic hepatic failure (HP:0100626)5.38573393
2Obstructive sleep apnea (HP:0002870)4.68947863
3Abnormality of the aortic arch (HP:0012303)4.37471911
4Abnormality of the fingertips (HP:0001211)4.27992803
5Agammaglobulinemia (HP:0004432)4.20726616
6Cellulitis (HP:0100658)3.56661883
7Abnormality of the intervertebral disk (HP:0005108)3.52273282
8Stomatitis (HP:0010280)3.50576125
9Genetic anticipation (HP:0003743)3.32798855
10Panhypogammaglobulinemia (HP:0003139)3.25038070
11Loss of speech (HP:0002371)3.04648868
12Papilloma (HP:0012740)2.98755586
13Verrucae (HP:0200043)2.98755586
14Abnormality of the nasal septum (HP:0000419)2.98579630
15Recurrent viral infections (HP:0004429)2.98252643
16Long eyelashes (HP:0000527)2.95991768
17Gastrointestinal inflammation (HP:0004386)2.94481471
18Dynein arm defect of respiratory motile cilia (HP:0012255)2.92596501
19Absent/shortened dynein arms (HP:0200106)2.92596501
20Inflammation of the large intestine (HP:0002037)2.91468361
21Abnormal delayed hypersensitivity skin test (HP:0002963)2.90079580
22Colitis (HP:0002583)2.89067334
23Progressive inability to walk (HP:0002505)2.83686728
24Elevated erythrocyte sedimentation rate (HP:0003565)2.81115070
25Short 4th metacarpal (HP:0010044)2.71581795
26Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.71581795
27Hyperacusis (HP:0010780)2.69799836
28Rectal prolapse (HP:0002035)2.65712625
29Recurrent fungal infections (HP:0002841)2.63094081
30Tented upper lip vermilion (HP:0010804)2.57900050
31Stereotypic behavior (HP:0000733)2.56886620
32Meningitis (HP:0001287)2.53415012
33Thyroiditis (HP:0100646)2.51465952
34Abnormality of B cell number (HP:0010975)2.50958763
35B lymphocytopenia (HP:0010976)2.50958763
36Mitral regurgitation (HP:0001653)2.49891662
37Abnormality of the columella (HP:0009929)2.45537404
38Anal stenosis (HP:0002025)2.44078736
39Broad face (HP:0000283)2.42850816
40Recurrent bronchitis (HP:0002837)2.41694315
41Aortic regurgitation (HP:0001659)2.37705595
42Thin bony cortex (HP:0002753)2.35625955
43Limited elbow extension (HP:0001377)2.35531993
44Mutism (HP:0002300)2.35039391
45Trigonocephaly (HP:0000243)2.33900578
46Elfin facies (HP:0004428)2.33887686
47T lymphocytopenia (HP:0005403)2.33526959
48Abnormal number of erythroid precursors (HP:0012131)2.28723579
49Stridor (HP:0010307)2.27876318
50Hypochromic anemia (HP:0001931)2.27012989
51IgM deficiency (HP:0002850)2.24821711
52Heterotopia (HP:0002282)2.24570501
53Uterine leiomyosarcoma (HP:0002891)2.23957957
54Leiomyosarcoma (HP:0100243)2.23957957
55Premature ovarian failure (HP:0008209)2.21167578
56Annular pancreas (HP:0001734)2.20622607
57High anterior hairline (HP:0009890)2.18513526
58Increased nuchal translucency (HP:0010880)2.18061359
59Clumsiness (HP:0002312)2.17721184
60Bulbous nose (HP:0000414)2.17287156
61Lymphangioma (HP:0100764)2.15506363
62Abnormality of T cell number (HP:0011839)2.15085993
63Ectopic kidney (HP:0000086)2.14806602
64Hypergonadotropic hypogonadism (HP:0000815)2.13181345
65Chronic mucocutaneous candidiasis (HP:0002728)2.12544858
66Recurrent cutaneous fungal infections (HP:0011370)2.12544858
67Supernumerary bones of the axial skeleton (HP:0009144)2.11918215
68Congenital stationary night blindness (HP:0007642)2.10778050
69Myositis (HP:0100614)2.10598835
70Renovascular hypertension (HP:0100817)2.08688091
71Shawl scrotum (HP:0000049)2.08248321
72Acute lymphatic leukemia (HP:0006721)2.08020542
73Morphological abnormality of the middle ear (HP:0008609)2.05892705
74Abnormality of the phalanges of the hallux (HP:0010057)2.04059048
75Cutis marmorata (HP:0000965)2.03692065
76Abnormality of incisor morphology (HP:0011063)2.00701247
77Abnormal number of incisors (HP:0011064)1.99693371
78Recurrent otitis media (HP:0000403)1.99433160
79Chromosomal breakage induced by crosslinking agents (HP:0003221)1.98575104
80Transitional cell carcinoma of the bladder (HP:0006740)1.97546790
81Obsessive-compulsive behavior (HP:0000722)1.96407235
82Progressive cerebellar ataxia (HP:0002073)1.95893548
83Eczematoid dermatitis (HP:0000976)1.94179086
84Abnormality of the incisor (HP:0000676)1.92658192
85Cystic liver disease (HP:0006706)1.92545607
86Hypoplastic ischia (HP:0003175)1.92538295
87Autoimmune thrombocytopenia (HP:0001973)1.92031306
88Ulnar bowing (HP:0003031)1.91023315
89Narrow palate (HP:0000189)1.90581938
90Severe combined immunodeficiency (HP:0004430)1.90574572
91Volvulus (HP:0002580)1.90569961
92Abnormality of cells of the lymphoid lineage (HP:0012140)1.90269542
93Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.89159317
94Increased density of long bones (HP:0006392)1.89146107
95Vertebral arch anomaly (HP:0008438)1.88916266
96Combined immunodeficiency (HP:0005387)1.88537612
97Spondylolisthesis (HP:0003302)1.87484688
98Sleep apnea (HP:0010535)1.87092086
99Macroorchidism (HP:0000053)1.87020019
100Orchitis (HP:0100796)1.87018564
101Flat cornea (HP:0007720)1.86716912
102Abnormality of the 4th metacarpal (HP:0010012)1.86358653
103Mesangial abnormality (HP:0001966)1.83402794
104Sepsis (HP:0100806)1.83362857
105Recurrent sinusitis (HP:0011108)1.82841262
106Lymphopenia (HP:0001888)1.81464089
107Vitreoretinal degeneration (HP:0000655)1.81365573
108Severe visual impairment (HP:0001141)1.81086796
109Chromsome breakage (HP:0040012)1.80618290
110Retrobulbar optic neuritis (HP:0100654)1.79356409
111Optic neuritis (HP:0100653)1.79356409
112Renal duplication (HP:0000075)1.79118866
113Abnormality of the right ventricle (HP:0001707)1.78351808
114Disproportionate tall stature (HP:0001519)1.78196390
115Long palpebral fissure (HP:0000637)1.77678652
116Bicuspid aortic valve (HP:0001647)1.75946091
117Ureteral stenosis (HP:0000071)1.74384328
118Prolonged bleeding time (HP:0003010)1.72774521
119Abnormality of cells of the erythroid lineage (HP:0012130)1.72663036
120Pointed chin (HP:0000307)1.72022239
121Spontaneous hematomas (HP:0007420)1.71917937
122Chronic otitis media (HP:0000389)1.71840284
123Bladder carcinoma (HP:0002862)1.71564306
124Bladder neoplasm (HP:0009725)1.71564306
125Anomalous pulmonary venous return (HP:0010772)1.70524201
126Abnormality of T cells (HP:0002843)1.70131932
127Pustule (HP:0200039)1.69766991
128Broad hallux (HP:0010055)1.69284272
129Shallow orbits (HP:0000586)1.68955655
130Aortic aneurysm (HP:0004942)1.68853401
131Overriding aorta (HP:0002623)1.68379239
132Thick eyebrow (HP:0000574)1.67497299
133Prominent nose (HP:0000448)1.66417815
134Gastrointestinal stroma tumor (HP:0100723)1.66220913
135Hepatoblastoma (HP:0002884)1.65961222
136Neoplasm of the adrenal cortex (HP:0100641)1.65492263
137Impaired smooth pursuit (HP:0007772)1.64932872
138Rib fusion (HP:0000902)1.64707765
139Chronic sinusitis (HP:0011109)1.64464822
140Urethral obstruction (HP:0000796)1.64147595
141Malignant gastrointestinal tract tumors (HP:0006749)1.63459736
142Gastrointestinal carcinoma (HP:0002672)1.63459736
143Recurrent abscess formation (HP:0002722)1.63308603
144Neoplasm of the heart (HP:0100544)1.63182391
145Cerebral aneurysm (HP:0004944)1.62809223
146Broad toe (HP:0001837)1.62384697
147Skin tags (HP:0010609)1.61484729
148Emphysema (HP:0002097)1.60619757
149Patellar dislocation (HP:0002999)1.59798337
150Intestinal fistula (HP:0100819)1.59344430
151Supernumerary ribs (HP:0005815)1.58964614
152Intellectual disability, severe (HP:0010864)1.58931239
153Abnormality of the radial head (HP:0003995)1.57608545
154Ureteral obstruction (HP:0006000)1.56592495
155Abnormality of ocular smooth pursuit (HP:0000617)1.55225460
156Basal cell carcinoma (HP:0002671)1.55213345
157Chest pain (HP:0100749)1.55176884
158Abnormality of the pulmonary veins (HP:0011718)1.55156286
159Osteomyelitis (HP:0002754)1.54146472
160Spinal cord lesions (HP:0100561)1.53480115
161Syringomyelia (HP:0003396)1.53480115
162Genu recurvatum (HP:0002816)1.53394358
163Recurrent lower respiratory tract infections (HP:0002783)1.53301051
164Deep philtrum (HP:0002002)1.52754482
165Short philtrum (HP:0000322)1.52332114
166Gastrointestinal infarctions (HP:0005244)1.52017650
167Ventricular tachycardia (HP:0004756)1.51874027
168Thin ribs (HP:0000883)1.51460187

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PASK5.78443394
2MAP3K105.40666269
3MAP3K134.08346703
4SIK33.93583189
5MAP4K13.91058577
6CDK123.72217601
7CAMKK13.60530750
8SIK23.23863789
9EEF2K2.79479729
10BRD42.57049098
11ERN12.38223026
12FGFR32.14715810
13GRK61.96415674
14ICK1.91182110
15BLK1.88022495
16TRIB31.78257933
17CAMK1G1.77485291
18STK101.73259563
19SIK11.60490768
20FGFR41.53151857
21CAMK1D1.51513737
22MAP3K141.42479103
23NEK21.36940403
24MAP3K71.35108514
25MARK21.33499804
26TXK1.27638641
27CSF1R1.27360449
28BTK1.25068363
29DMPK1.22559553
30IKBKB1.21995331
31SYK1.20376355
32FGFR21.18114577
33TYRO31.16299681
34SMG11.13719923
35CDK41.11530029
36HCK1.11486061
37ITK1.10379154
38CSK1.10186924
39MELK1.03777432
40PRKD21.01935620
41MAP3K111.01839743
42CLK10.99383190
43PKN20.95953495
44MARK30.95657213
45NTRK20.95573246
46LRRK20.94460608
47CDK90.94070747
48TYK20.92866693
49TGFBR20.92641951
50RPS6KL10.91617348
51RPS6KA60.91583789
52HIPK20.91311629
53ZAP700.90702755
54STK380.90594551
55CHUK0.90062830
56MTOR0.89429347
57MAP2K20.88057579
58UHMK10.87054917
59ADRBK20.81798551
60JAK30.81101852
61CAMKK20.80926015
62PDGFRA0.79044048
63RPS6KA20.78535205
64DYRK30.77902682
65FES0.77683480
66CDC42BPA0.77204353
67PRKD30.76608070
68MAPK150.75894915
69JAK10.74376095
70CAMK40.72908178
71PTK60.72097180
72TNK20.71773905
73PIM10.71332273
74RIPK10.70064598
75IRAK40.69225622
76IRAK30.68718723
77LCK0.68148307
78MAP2K60.66768440
79PRKCZ0.65558536
80MAP2K30.64887399
81KIT0.64360776
82IRAK20.64329634
83LYN0.64161274
84MAPK110.63672200
85TTN0.62607540
86FGFR10.61895506
87TAOK30.61319485
88BUB10.59650006
89PRKCH0.59474570
90BMX0.58538990
91STK40.58069332
92DYRK1B0.57059922
93EPHB20.56762126
94TBK10.54936522
95PRKD10.54423889
96MATK0.54407727
97DAPK20.53895437
98PDK10.52179475
99IKBKE0.51221279
100CDK70.50082176
101PDGFRB0.49826968
102PRKAA20.49826110
103MAPK70.49286411
104SGK2230.48888501
105SGK4940.48888501
106WNK10.48411819
107CDK80.48183674
108KSR10.48109789
109ATR0.46017033
110TAOK10.45579579
111ALK0.45499603
112SGK30.43121083
113EPHB10.42872935
114AKT20.42526660
115MAPK120.42285984
116NUAK10.41859602
117PDPK10.41557987
118MAPK40.40918396
119RPS6KA40.40829081
120BCKDK0.40416366
121RPS6KA10.39886725
122CHEK10.39332497
123PRPF4B0.39226953
124RIPK40.38010447
125PRKCQ0.37540706
126STK110.37209721
127TAOK20.37175744
128CDK60.37095942
129MAPK90.36357653
130YES10.35445437
131MAPKAPK20.35230748
132CAMK10.34502683
133INSRR0.34473938
134RPS6KC10.34411487
135WNK40.34059213
136IRAK10.33393060
137FRK0.33348719
138PRKAA10.30544051

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.11648497
2B cell receptor signaling pathway_Homo sapiens_hsa046622.63049535
3Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.41981262
4Notch signaling pathway_Homo sapiens_hsa043302.36780133
5Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.01417845
6Lysine degradation_Homo sapiens_hsa003101.80560449
7Chronic myeloid leukemia_Homo sapiens_hsa052201.79973600
8Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.69611386
9T cell receptor signaling pathway_Homo sapiens_hsa046601.66773245
10Osteoclast differentiation_Homo sapiens_hsa043801.62740772
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.60087357
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.54488817
13Acute myeloid leukemia_Homo sapiens_hsa052211.48966729
14Leishmaniasis_Homo sapiens_hsa051401.48116370
15Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.39415703
16Colorectal cancer_Homo sapiens_hsa052101.34408094
17Non-small cell lung cancer_Homo sapiens_hsa052231.32009442
18MicroRNAs in cancer_Homo sapiens_hsa052061.31402050
19Measles_Homo sapiens_hsa051621.31262537
20Thyroid hormone signaling pathway_Homo sapiens_hsa049191.29088506
21Neurotrophin signaling pathway_Homo sapiens_hsa047221.28961748
22Cocaine addiction_Homo sapiens_hsa050301.26962478
23Pancreatic cancer_Homo sapiens_hsa052121.26781916
24Chemokine signaling pathway_Homo sapiens_hsa040621.26501079
25Hematopoietic cell lineage_Homo sapiens_hsa046401.23973381
26Base excision repair_Homo sapiens_hsa034101.22946332
27GnRH signaling pathway_Homo sapiens_hsa049121.21824559
28Viral myocarditis_Homo sapiens_hsa054161.20474993
29Transcriptional misregulation in cancer_Homo sapiens_hsa052021.19390711
30Basal cell carcinoma_Homo sapiens_hsa052171.18516346
31Cholinergic synapse_Homo sapiens_hsa047251.17734453
32AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.16991856
33Hepatitis B_Homo sapiens_hsa051611.16349185
34HTLV-I infection_Homo sapiens_hsa051661.13305618
35mTOR signaling pathway_Homo sapiens_hsa041501.13029862
36Shigellosis_Homo sapiens_hsa051311.11930722
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11194896
38Leukocyte transendothelial migration_Homo sapiens_hsa046701.08018776
39Herpes simplex infection_Homo sapiens_hsa051681.07812609
40Platelet activation_Homo sapiens_hsa046111.07800656
41Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.06686633
42Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.06337223
43Toll-like receptor signaling pathway_Homo sapiens_hsa046201.05872842
44Jak-STAT signaling pathway_Homo sapiens_hsa046301.05479363
45Cyanoamino acid metabolism_Homo sapiens_hsa004601.03906170
46Phosphatidylinositol signaling system_Homo sapiens_hsa040701.03085416
47Insulin secretion_Homo sapiens_hsa049111.02083882
48VEGF signaling pathway_Homo sapiens_hsa043701.01478779
49Autoimmune thyroid disease_Homo sapiens_hsa053201.01276436
50Endometrial cancer_Homo sapiens_hsa052131.01002868
51alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.01000095
52Dorso-ventral axis formation_Homo sapiens_hsa043201.00426086
53Morphine addiction_Homo sapiens_hsa050321.00173615
54Allograft rejection_Homo sapiens_hsa053300.99434179
55Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.99418298
56mRNA surveillance pathway_Homo sapiens_hsa030150.98208745
57Toxoplasmosis_Homo sapiens_hsa051450.96641515
58Renal cell carcinoma_Homo sapiens_hsa052110.95512384
59Long-term potentiation_Homo sapiens_hsa047200.95209806
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.93832028
61Graft-versus-host disease_Homo sapiens_hsa053320.93723049
62Apoptosis_Homo sapiens_hsa042100.92569248
63Small cell lung cancer_Homo sapiens_hsa052220.91143885
64Adherens junction_Homo sapiens_hsa045200.90500984
65Phototransduction_Homo sapiens_hsa047440.90464847
66Influenza A_Homo sapiens_hsa051640.89474956
67Choline metabolism in cancer_Homo sapiens_hsa052310.89130888
68ABC transporters_Homo sapiens_hsa020100.89085702
69Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.87784716
70Proteoglycans in cancer_Homo sapiens_hsa052050.87534661
71Type II diabetes mellitus_Homo sapiens_hsa049300.87493817
72Adipocytokine signaling pathway_Homo sapiens_hsa049200.87479664
73Ovarian steroidogenesis_Homo sapiens_hsa049130.86971546
74ErbB signaling pathway_Homo sapiens_hsa040120.86719531
75Pathways in cancer_Homo sapiens_hsa052000.85809586
76cAMP signaling pathway_Homo sapiens_hsa040240.85402796
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84604526
78MAPK signaling pathway_Homo sapiens_hsa040100.84366256
79Glioma_Homo sapiens_hsa052140.83236106
80RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.81685362
81FoxO signaling pathway_Homo sapiens_hsa040680.81174617
82Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.80710043
83Staphylococcus aureus infection_Homo sapiens_hsa051500.80419881
84Phospholipase D signaling pathway_Homo sapiens_hsa040720.79060067
85Amphetamine addiction_Homo sapiens_hsa050310.78654563
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.78053081
87Prolactin signaling pathway_Homo sapiens_hsa049170.77894573
88Tuberculosis_Homo sapiens_hsa051520.77783293
89Linoleic acid metabolism_Homo sapiens_hsa005910.77625279
90Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77124747
91Inositol phosphate metabolism_Homo sapiens_hsa005620.77081584
92Glycerophospholipid metabolism_Homo sapiens_hsa005640.76757452
93TNF signaling pathway_Homo sapiens_hsa046680.76656366
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.75986625
95Hedgehog signaling pathway_Homo sapiens_hsa043400.75411911
96Spliceosome_Homo sapiens_hsa030400.74310495
97Wnt signaling pathway_Homo sapiens_hsa043100.74065306
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.73627838
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.71916500
100Cell cycle_Homo sapiens_hsa041100.71914825
101Axon guidance_Homo sapiens_hsa043600.71458581
102Endocytosis_Homo sapiens_hsa041440.71388890
103Epstein-Barr virus infection_Homo sapiens_hsa051690.70986397
104Taste transduction_Homo sapiens_hsa047420.70843724
105Rap1 signaling pathway_Homo sapiens_hsa040150.69440457
106Viral carcinogenesis_Homo sapiens_hsa052030.69395193
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.69026391
108Glycerolipid metabolism_Homo sapiens_hsa005610.68866938
109Melanogenesis_Homo sapiens_hsa049160.67313631
110NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65899509
111Ras signaling pathway_Homo sapiens_hsa040140.65790764
112Salmonella infection_Homo sapiens_hsa051320.65725300
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65409615
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63961213
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.63469958
116Insulin resistance_Homo sapiens_hsa049310.63426781
117Circadian entrainment_Homo sapiens_hsa047130.63340311
118Aldosterone synthesis and secretion_Homo sapiens_hsa049250.63000295
119Hippo signaling pathway_Homo sapiens_hsa043900.62687881
120Prostate cancer_Homo sapiens_hsa052150.62657338
121Type I diabetes mellitus_Homo sapiens_hsa049400.61999178
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61882488
123Antigen processing and presentation_Homo sapiens_hsa046120.61204233
124Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.60964160
125Sulfur relay system_Homo sapiens_hsa041220.60712898
126African trypanosomiasis_Homo sapiens_hsa051430.60262121
127Maturity onset diabetes of the young_Homo sapiens_hsa049500.59268652
128Gastric acid secretion_Homo sapiens_hsa049710.58944671
129Oxytocin signaling pathway_Homo sapiens_hsa049210.58825235
130Bladder cancer_Homo sapiens_hsa052190.58289609
131Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.58201799
132Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.57731255
133Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57022970
134Hepatitis C_Homo sapiens_hsa051600.56685879
135Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.56450815
136cGMP-PKG signaling pathway_Homo sapiens_hsa040220.56417204
137Focal adhesion_Homo sapiens_hsa045100.54991732
138Sphingolipid signaling pathway_Homo sapiens_hsa040710.53530333
139Dilated cardiomyopathy_Homo sapiens_hsa054140.53005457
140Estrogen signaling pathway_Homo sapiens_hsa049150.51448266
141Non-homologous end-joining_Homo sapiens_hsa034500.49892941

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