GLTSCR2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)6.61199918
2ribosomal small subunit assembly (GO:0000028)6.59384370
3translational termination (GO:0006415)6.33820914
4translational elongation (GO:0006414)5.62870125
5ribosomal small subunit biogenesis (GO:0042274)5.43736930
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.31371953
7negative regulation of cell killing (GO:0031342)5.31371953
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.17848897
9nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.17542069
10protein targeting to ER (GO:0045047)5.04145942
11maturation of SSU-rRNA (GO:0030490)5.03800259
12cotranslational protein targeting to membrane (GO:0006613)5.00652770
13translational initiation (GO:0006413)4.96432573
14viral life cycle (GO:0019058)4.91080131
15cellular protein complex disassembly (GO:0043624)4.83463259
16establishment of protein localization to endoplasmic reticulum (GO:0072599)4.78990983
17antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.75482101
18protein localization to endoplasmic reticulum (GO:0070972)4.69900798
19negative thymic T cell selection (GO:0045060)4.45845345
20protein complex disassembly (GO:0043241)4.45396754
21ribosomal large subunit biogenesis (GO:0042273)4.39276852
22T cell selection (GO:0045058)4.23709459
23antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.20250948
24antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.20250948
25macromolecular complex disassembly (GO:0032984)4.14885546
26formation of translation preinitiation complex (GO:0001731)4.12334341
27positive T cell selection (GO:0043368)4.10932254
28modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.97939526
29positive regulation by organism of defense response of other organism involved in symbiotic interact3.97939526
30modulation by symbiont of host immune response (GO:0052553)3.97939526
31positive regulation by symbiont of host defense response (GO:0052509)3.97939526
32modulation by symbiont of host defense response (GO:0052031)3.97939526
33modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.97939526
34DNA deamination (GO:0045006)3.95603308
35regulation of B cell receptor signaling pathway (GO:0050855)3.88352370
36antigen processing and presentation of endogenous antigen (GO:0019883)3.83897855
37nuclear-transcribed mRNA catabolic process (GO:0000956)3.83497196
38tolerance induction (GO:0002507)3.79338164
39positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.73645827
40leukocyte aggregation (GO:0070486)3.73366635
41B cell receptor signaling pathway (GO:0050853)3.72535582
42detection of bacterium (GO:0016045)3.71426166
43mannose metabolic process (GO:0006013)3.70493212
44mRNA catabolic process (GO:0006402)3.66057953
45ribonucleoprotein complex biogenesis (GO:0022613)3.66055125
46DNA unwinding involved in DNA replication (GO:0006268)3.65776115
47response to muramyl dipeptide (GO:0032495)3.64699048
48RNA catabolic process (GO:0006401)3.55942893
49Peyers patch development (GO:0048541)3.52389530
50mucosal-associated lymphoid tissue development (GO:0048537)3.52389530
51detection of other organism (GO:0098543)3.49703431
52positive regulation of gamma-delta T cell activation (GO:0046645)3.38725931
53DNA strand elongation involved in DNA replication (GO:0006271)3.35207493
54regulation of B cell differentiation (GO:0045577)3.32570832
55protein targeting to membrane (GO:0006612)3.32248388
56regulation of gamma-delta T cell differentiation (GO:0045586)3.31467125
57translation (GO:0006412)3.21847806
58DNA strand elongation (GO:0022616)3.18117141
59T cell migration (GO:0072678)3.16800082
60negative regulation of phagocytosis (GO:0050765)3.13416429
61positive regulation of granulocyte differentiation (GO:0030854)3.12433796
62DNA replication initiation (GO:0006270)3.10686920
63ncRNA 3-end processing (GO:0043628)3.10450003
64folic acid-containing compound biosynthetic process (GO:0009396)3.09970926
65negative regulation of lymphocyte mediated immunity (GO:0002707)3.09679188
66telomere maintenance via semi-conservative replication (GO:0032201)3.08787683
67response to interleukin-15 (GO:0070672)3.06704696
68modulation by virus of host process (GO:0019054)3.04664426
69negative regulation of leukocyte mediated immunity (GO:0002704)2.96932491
70regulation of interleukin-2 biosynthetic process (GO:0045076)2.95497019
71rRNA processing (GO:0006364)2.95021966
72regulation of gamma-delta T cell activation (GO:0046643)2.94286711
73immunoglobulin mediated immune response (GO:0016064)2.93283830
74regulation of granulocyte differentiation (GO:0030852)2.92945114
75regulation of T cell tolerance induction (GO:0002664)2.92787300
76germinal center formation (GO:0002467)2.90247944
77response to peptidoglycan (GO:0032494)2.88864632
78histone H3-K36 demethylation (GO:0070544)2.88593138
79negative regulation of T cell mediated immunity (GO:0002710)2.87748831
80rRNA metabolic process (GO:0016072)2.85322170
81negative regulation of innate immune response (GO:0045824)2.84260156
82antigen receptor-mediated signaling pathway (GO:0050851)2.83837760
83natural killer cell differentiation (GO:0001779)2.82930201
84response to laminar fluid shear stress (GO:0034616)2.81383257
85negative regulation of RNA splicing (GO:0033119)2.80935491
86positive thymic T cell selection (GO:0045059)2.80823913
87modulation by symbiont of host cellular process (GO:0044068)2.79721641
88ribosome biogenesis (GO:0042254)2.79513544
89IMP biosynthetic process (GO:0006188)2.79202849
90regulation of dendritic cell antigen processing and presentation (GO:0002604)2.79076917
91negative regulation of granulocyte differentiation (GO:0030853)2.78096740
92macrophage activation involved in immune response (GO:0002281)2.78078602
93negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.76970910
94protein localization to kinetochore (GO:0034501)2.75257345
95regulation of tolerance induction (GO:0002643)2.74235072
96negative regulation of erythrocyte differentiation (GO:0045647)2.74044918
97regulation of alpha-beta T cell proliferation (GO:0046640)2.71634342
98mitotic nuclear envelope disassembly (GO:0007077)2.69811013
99positive regulation of Rap GTPase activity (GO:0032854)2.69540062
100T cell homeostasis (GO:0043029)2.69315381
101antigen processing and presentation via MHC class Ib (GO:0002475)2.66216921
102regulation of necroptotic process (GO:0060544)2.65148931
103regulation of natural killer cell mediated immunity (GO:0002715)2.64474312
104regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.64474312
1053-UTR-mediated mRNA stabilization (GO:0070935)2.63156055
106T cell receptor signaling pathway (GO:0050852)2.63051178
107negative regulation of translational initiation (GO:0045947)2.62402444
108CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.62219691
109telomere maintenance via recombination (GO:0000722)2.61464149
110response to type I interferon (GO:0034340)2.61057380
111lymphocyte homeostasis (GO:0002260)2.60763767
112negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.58724574
113response to interleukin-4 (GO:0070670)2.58328292
114response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.57589856
115response to host immune response (GO:0052572)2.57589856
116T cell costimulation (GO:0031295)2.57448969
117DNA duplex unwinding (GO:0032508)2.57226503
118cellular response to type I interferon (GO:0071357)2.57105915
119type I interferon signaling pathway (GO:0060337)2.57105915
120neutrophil activation involved in immune response (GO:0002283)2.56313189
121positive regulation of histone deacetylation (GO:0031065)2.55594700
122defense response to protozoan (GO:0042832)2.54650144
123regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.54426708
124regulation of antigen processing and presentation (GO:0002577)2.54335091
125DNA geometric change (GO:0032392)2.54109651
126response to host (GO:0075136)2.53887293
127response to host defenses (GO:0052200)2.53887293
128response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.53887293
129detection of external biotic stimulus (GO:0098581)2.53330622
130Arp2/3 complex-mediated actin nucleation (GO:0034314)2.53286466
131IMP metabolic process (GO:0046040)2.53260880
132lymphocyte costimulation (GO:0031294)2.52878316
133nucleobase biosynthetic process (GO:0046112)2.52207557
134negative regulation of histone methylation (GO:0031061)2.49819339
135telomere maintenance via telomere lengthening (GO:0010833)2.49725229
136protein localization to chromosome, centromeric region (GO:0071459)2.47443879
137DNA replication checkpoint (GO:0000076)2.46420148
138positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.45956094
139maternal placenta development (GO:0001893)2.44477901
140mitotic recombination (GO:0006312)2.43965600
141membrane disassembly (GO:0030397)2.43939698
142nuclear envelope disassembly (GO:0051081)2.43939698
143regulation of histone H3-K9 methylation (GO:0051570)2.43760036
144spliceosomal snRNP assembly (GO:0000387)2.42272123
145NIK/NF-kappaB signaling (GO:0038061)2.41009869
146regulation of type I interferon-mediated signaling pathway (GO:0060338)2.39511897
147T cell apoptotic process (GO:0070231)2.38607335
148cellular component biogenesis (GO:0044085)2.38207766
149regulation of translational fidelity (GO:0006450)2.37609815
150morphogenesis of an endothelium (GO:0003159)2.37155951
151endothelial tube morphogenesis (GO:0061154)2.37155951
152thymic T cell selection (GO:0045061)2.37153393
153dosage compensation (GO:0007549)2.36538033
154mRNA splicing, via spliceosome (GO:0000398)2.36438472
155RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.36438472
156ribosome assembly (GO:0042255)2.35960952
157positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.35590084
158RNA splicing, via transesterification reactions (GO:0000375)2.35564290
159regulation of posttranscriptional gene silencing (GO:0060147)2.33903959
160regulation of gene silencing by miRNA (GO:0060964)2.33903959
161regulation of gene silencing by RNA (GO:0060966)2.33903959
162regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.33616624
163heterochromatin organization (GO:0070828)2.30941811
164pseudouridine synthesis (GO:0001522)2.30061678
165regulation of translation in response to stress (GO:0043555)2.28260072
166DNA replication-dependent nucleosome organization (GO:0034723)2.26520414
167DNA replication-dependent nucleosome assembly (GO:0006335)2.26520414
168trophectodermal cell differentiation (GO:0001829)2.26371898
169purine nucleobase biosynthetic process (GO:0009113)2.23960212
170nucleotide-excision repair, DNA gap filling (GO:0006297)2.22912953
171regulation of interleukin-12 biosynthetic process (GO:0045075)2.22414694
172negative T cell selection (GO:0043383)2.19899471
173positive regulation of B cell differentiation (GO:0045579)2.18860994
174cellular response to interleukin-4 (GO:0071353)2.18766797

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.83252487
2* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.48246024
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.37515784
4MYC_22102868_ChIP-Seq_BL_Human3.02576815
5FOXM1_23109430_ChIP-Seq_U2OS_Human2.84652810
6KDM2B_26808549_Chip-Seq_SUP-B15_Human2.72421664
7LXR_22292898_ChIP-Seq_THP-1_Human2.57769921
8* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.54847189
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.36875626
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.36213381
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.24748615
12VDR_21846776_ChIP-Seq_THP-1_Human2.23969058
13THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.21223003
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.18845021
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.16060517
16XRN2_22483619_ChIP-Seq_HELA_Human2.11386771
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.09461915
18SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.00694755
19TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.98531137
20* ETS1_20019798_ChIP-Seq_JURKAT_Human1.93476003
21EST1_17652178_ChIP-ChIP_JURKAT_Human1.83767046
22VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.79254134
23* RACK7_27058665_Chip-Seq_MCF-7_Human1.77572861
24ELF1_17652178_ChIP-ChIP_JURKAT_Human1.77096061
25SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.73600552
26KDM2B_26808549_Chip-Seq_JURKAT_Human1.73311673
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.71535870
28TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69266576
29* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.66959041
30* CIITA_25753668_ChIP-Seq_RAJI_Human1.66741471
31GABP_17652178_ChIP-ChIP_JURKAT_Human1.66712106
32NELFA_20434984_ChIP-Seq_ESCs_Mouse1.64871946
33* VDR_23849224_ChIP-Seq_CD4+_Human1.63722272
34MAF_26560356_Chip-Seq_TH1_Human1.63356105
35RUNX_20019798_ChIP-Seq_JUKART_Human1.62030321
36P68_20966046_ChIP-Seq_HELA_Human1.61846034
37SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.60462596
38SA1_27219007_Chip-Seq_ERYTHROID_Human1.59644620
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57768932
40FOXP3_21729870_ChIP-Seq_TREG_Human1.57528547
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.56967831
42TP63_17297297_ChIP-ChIP_HaCaT_Human1.55468673
43HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.55195529
44SCL_19346495_ChIP-Seq_HPC-7_Human1.54091261
45CREB1_15753290_ChIP-ChIP_HEK293T_Human1.53536934
46NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.51696060
47RARG_19884340_ChIP-ChIP_MEFs_Mouse1.51395543
48CTCF_27219007_Chip-Seq_ERYTHROID_Human1.50992089
49IRF8_22096565_ChIP-ChIP_GC-B_Human1.50399982
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.50371009
51UTX_26944678_Chip-Seq_JUKART_Human1.49234173
52NANOG_18555785_ChIP-Seq_MESCs_Mouse1.48687493
53NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.46972080
54* TCF7_22412390_ChIP-Seq_EML_Mouse1.46929685
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.46082671
56STAT3_1855785_ChIP-Seq_MESCs_Mouse1.46053969
57IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.44719272
58* TTF2_22483619_ChIP-Seq_HELA_Human1.44524676
59EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44465488
60KDM2B_26808549_Chip-Seq_K562_Human1.44045870
61SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.43438475
62SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.42824633
63E2F1_18555785_ChIP-Seq_MESCs_Mouse1.42035506
64TET1_21451524_ChIP-Seq_MESCs_Mouse1.41904962
65MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.41828913
66RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.40191886
67TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.39788299
68ELF1_20517297_ChIP-Seq_JURKAT_Human1.39786023
69NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.39150379
70BCL6_27268052_Chip-Seq_Bcells_Human1.35976844
71* GABP_19822575_ChIP-Seq_HepG2_Human1.35387182
72SPI1_23127762_ChIP-Seq_K562_Human1.35386895
73* ELK3_25401928_ChIP-Seq_HUVEC_Human1.34361158
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.34092107
75DCP1A_22483619_ChIP-Seq_HELA_Human1.33678167
76BCOR_27268052_Chip-Seq_Bcells_Human1.33369213
77IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.32126459
78E2F1_21310950_ChIP-Seq_MCF-7_Human1.30920399
79PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.30862411
80CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.30065639
81* MAF_26560356_Chip-Seq_TH2_Human1.29454158
82SMC4_20622854_ChIP-Seq_HELA_Human1.29254932
83POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.29070862
84MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.28740067
85* MYB_26560356_Chip-Seq_TH2_Human1.28057635
86* SPI1_23547873_ChIP-Seq_NB4_Human1.27603966
87PU.1_20513432_ChIP-Seq_Bcells_Mouse1.27044369
88GATA1_19941827_ChIP-Seq_MEL_Mouse1.27007588
89* MYB_26560356_Chip-Seq_TH1_Human1.26770000
90STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.26532129
91CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26459187
92ERG_20887958_ChIP-Seq_HPC-7_Mouse1.26447904
93EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.25245106
94PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.24661650
95ZFX_18555785_ChIP-Seq_MESCs_Mouse1.22114153
96CREB1_26743006_Chip-Seq_LNCaP_Human1.21724861
97GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21133973
98POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.20487437
99KDM5A_27292631_Chip-Seq_BREAST_Human1.20395300
100KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.20323443
101KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.19953893
102STAT4_19710469_ChIP-ChIP_TH1__Mouse1.17705126
103ZFP281_18757296_ChIP-ChIP_E14_Mouse1.17599970
104MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.16104142
105KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.15963845
106VDR_24763502_ChIP-Seq_THP-1_Human1.15645966
107E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.15376375
108KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14461662
109* RUNX1_22412390_ChIP-Seq_EML_Mouse1.14116089
110IRF8_27001747_Chip-Seq_BMDM_Mouse1.14057044
111HOXB4_20404135_ChIP-ChIP_EML_Mouse1.13664629
112STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.13095408
113* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.12793600
114RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.12747188
115CTCF_26484167_Chip-Seq_Bcells_Mouse1.10715918
116MYCN_18555785_ChIP-Seq_MESCs_Mouse1.10547150
117* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.10198080
118DNAJC2_21179169_ChIP-ChIP_NT2_Human1.10089013
119IRF8_21731497_ChIP-ChIP_J774_Mouse1.09938075
120CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09937546
121KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.09880819
122KDM2B_26808549_Chip-Seq_DND41_Human1.09797095
123TP63_19390658_ChIP-ChIP_HaCaT_Human1.09341490
124* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.09052239
125AR_21909140_ChIP-Seq_LNCAP_Human1.08989114
126GATA1_22383799_ChIP-Seq_G1ME_Mouse1.08117389
127THAP11_20581084_ChIP-Seq_MESCs_Mouse1.07787700
128CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.07574087
129SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.07064289
130SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.05776204
131KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.05014342
132UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.04803650
133BRD4_27068464_Chip-Seq_AML-cells_Mouse1.04398364
134GATA1_19941826_ChIP-Seq_K562_Human1.04009742
135ZNF263_19887448_ChIP-Seq_K562_Human1.02710512
136KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.02584403
137NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.02278534
138SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.01485203
139PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01326658
140* CTCF_21964334_Chip-Seq_Bcells_Human1.01104813
141MYB_21317192_ChIP-Seq_ERMYB_Mouse1.01063581
142KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00695767
143TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.00621062
144YY1_21170310_ChIP-Seq_MESCs_Mouse1.00285508
145FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.00157350
146ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.99475951
147CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99129553
148GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.99030627
149FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.99025272
150CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.98389988
151KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97965005
152KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97965005
153KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97965005
154* NCOR1_26117541_ChIP-Seq_K562_Human0.96772969
155SRY_22984422_ChIP-ChIP_TESTIS_Rat0.96020449

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.15870696
2MP0003763_abnormal_thymus_physiology2.80945334
3MP0002396_abnormal_hematopoietic_system2.76826829
4MP0004957_abnormal_blastocyst_morpholog2.67503692
5MP0000685_abnormal_immune_system2.57574241
6MP0003111_abnormal_nucleus_morphology2.47392702
7MP0003077_abnormal_cell_cycle2.42442011
8MP0010094_abnormal_chromosome_stability2.40376780
9MP0001835_abnormal_antigen_presentation2.20925327
10MP0010352_gastrointestinal_tract_polyps2.15545722
11MP0005451_abnormal_body_composition2.10943330
12MP0001800_abnormal_humoral_immune2.07119538
13MP0004808_abnormal_hematopoietic_stem2.04347624
14MP0004381_abnormal_hair_follicle2.02548820
15MP0002398_abnormal_bone_marrow1.98617349
16MP0009333_abnormal_splenocyte_physiolog1.95292757
17MP0000490_abnormal_crypts_of1.90721976
18MP0008007_abnormal_cellular_replicative1.83808795
19MP0005671_abnormal_response_to1.80296818
20MP0000703_abnormal_thymus_morphology1.78189861
21MP0002722_abnormal_immune_system1.77888586
22MP0005058_abnormal_lysosome_morphology1.72919209
23MP0000689_abnormal_spleen_morphology1.72182020
24MP0008058_abnormal_DNA_repair1.70383989
25MP0001545_abnormal_hematopoietic_system1.70188168
26MP0005397_hematopoietic_system_phenotyp1.70188168
27MP0009278_abnormal_bone_marrow1.68325854
28MP0008057_abnormal_DNA_replication1.66699680
29MP0002452_abnormal_antigen_presenting1.65276258
30MP0001790_abnormal_immune_system1.63367162
31MP0005387_immune_system_phenotype1.63367162
32MP0002420_abnormal_adaptive_immunity1.62970406
33MP0001873_stomach_inflammation1.62645952
34MP0002166_altered_tumor_susceptibility1.61362614
35MP0000716_abnormal_immune_system1.61280946
36MP0001819_abnormal_immune_cell1.60587542
37MP0003436_decreased_susceptibility_to1.59173509
38MP0002723_abnormal_immune_serum1.57803248
39MP0002009_preneoplasia1.56837070
40MP0003172_abnormal_lysosome_physiology1.55892495
41MP0002429_abnormal_blood_cell1.55179363
42MP0010155_abnormal_intestine_physiology1.54430821
43MP0001533_abnormal_skeleton_physiology1.50556954
44MP0000350_abnormal_cell_proliferation1.49750958
45MP0004185_abnormal_adipocyte_glucose1.49169728
46MP0002405_respiratory_system_inflammati1.46403192
47MP0002019_abnormal_tumor_incidence1.45209862
48MP0005000_abnormal_immune_tolerance1.44199460
49MP0008260_abnormal_autophagy1.44176248
50MP0001730_embryonic_growth_arrest1.39989763
51MP0005025_abnormal_response_to1.38631713
52MP0003866_abnormal_defecation1.34527725
53MP0004947_skin_inflammation1.30643139
54MP0001851_eye_inflammation1.30170584
55MP0000465_gastrointestinal_hemorrhage1.30126028
56MP0009785_altered_susceptibility_to1.27808702
57MP0005666_abnormal_adipose_tissue1.27665437
58MP0003303_peritoneal_inflammation1.26900066
59MP0003786_premature_aging1.26753939
60MP0000858_altered_metastatic_potential1.25520100
61MP0002132_abnormal_respiratory_system1.25242972
62MP0006082_CNS_inflammation1.24797734
63MP0005023_abnormal_wound_healing1.24041144
64MP0001853_heart_inflammation1.23711548
65MP0002998_abnormal_bone_remodeling1.22775431
66MP0003300_gastrointestinal_ulcer1.22174500
67MP0005076_abnormal_cell_differentiation1.20992468
68MP0003705_abnormal_hypodermis_morpholog1.20592364
69MP0002796_impaired_skin_barrier1.20435609
70MP0010307_abnormal_tumor_latency1.20378603
71MP0000313_abnormal_cell_death1.18601998
72MP0002006_tumorigenesis1.17761452
73MP0001348_abnormal_lacrimal_gland1.16917801
74MP0004858_abnormal_nervous_system1.16451833
75MP0008932_abnormal_embryonic_tissue1.11381960
76MP0002080_prenatal_lethality1.10519077
77MP0003183_abnormal_peptide_metabolism1.10019552
78MP0001697_abnormal_embryo_size1.08200151
79MP0001672_abnormal_embryogenesis/_devel1.07863845
80MP0005380_embryogenesis_phenotype1.07863845
81MP0005310_abnormal_salivary_gland1.07182532
82MP0005464_abnormal_platelet_physiology1.06877148
83MP0001663_abnormal_digestive_system1.04929405
84MP0003984_embryonic_growth_retardation1.04496056
85MP0002088_abnormal_embryonic_growth/wei1.04154938
86MP0002086_abnormal_extraembryonic_tissu1.03981420
87MP0003566_abnormal_cell_adhesion1.03557895
88MP0005075_abnormal_melanosome_morpholog1.00064077
89MP0001845_abnormal_inflammatory_respons0.99330944
90MP0000477_abnormal_intestine_morphology0.99182643
91MP0000678_abnormal_parathyroid_gland0.99084605
92MP0003567_abnormal_fetal_cardiomyocyte0.96852835
93MP0004264_abnormal_extraembryonic_tissu0.96348655
94MP0004197_abnormal_fetal_growth/weight/0.95556065
95MP0006054_spinal_hemorrhage0.94942378
96MP0004130_abnormal_muscle_cell0.92856431
97MP0002085_abnormal_embryonic_tissue0.89891765
98MP0002084_abnormal_developmental_patter0.87577756
99MP0005501_abnormal_skin_physiology0.85904959
100MP0005375_adipose_tissue_phenotype0.85779867
101MP0003453_abnormal_keratinocyte_physiol0.83290234
102MP0005390_skeleton_phenotype0.82681184
103MP0001849_ear_inflammation0.81303719
104MP0002148_abnormal_hypersensitivity_rea0.80973563
105MP0003724_increased_susceptibility_to0.79981003
106MP0003091_abnormal_cell_migration0.79172756
107MP0002653_abnormal_ependyma_morphology0.78668418
108MP0010030_abnormal_orbit_morphology0.78411198
109MP0008995_early_reproductive_senescence0.78238787
110MP0005381_digestive/alimentary_phenotyp0.76964994
111MP0009840_abnormal_foam_cell0.76634617
112MP0000733_abnormal_muscle_development0.76397885
113MP0002419_abnormal_innate_immunity0.76050037
114MP0003448_altered_tumor_morphology0.75939475
115MP0001216_abnormal_epidermal_layer0.74913470
116MP0005409_darkened_coat_color0.73409751
117MP0009379_abnormal_foot_pigmentation0.73119625
118MP0003279_aneurysm0.73061824
119MP0004510_myositis0.72452272
120MP0002254_reproductive_system_inflammat0.71615892
121MP0009931_abnormal_skin_appearance0.69221862
122MP0000681_abnormal_thyroid_gland0.69158950
123MP0002249_abnormal_larynx_morphology0.69100249
124MP0003828_pulmonary_edema0.68078480
125MP0005166_decreased_susceptibility_to0.66989136
126MP0010234_abnormal_vibrissa_follicle0.66879611
127MP0003191_abnormal_cellular_cholesterol0.65178463
128MP0008469_abnormal_protein_level0.64638426
129MP0000598_abnormal_liver_morphology0.64307733
130MP0000249_abnormal_blood_vessel0.63505197
131MP0002933_joint_inflammation0.61964838
132MP0002138_abnormal_hepatobiliary_system0.61742559
133MP0009115_abnormal_fat_cell0.60521589
134MP0003795_abnormal_bone_structure0.58446126
135MP0008961_abnormal_basal_metabolism0.57383537
136MP0008004_abnormal_stomach_pH0.53142046

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.99679415
2Reticulocytopenia (HP:0001896)4.87976206
3Abnormal number of erythroid precursors (HP:0012131)4.60302207
4Thrombocytosis (HP:0001894)3.87529888
5Recurrent abscess formation (HP:0002722)3.53777615
6IgM deficiency (HP:0002850)3.49254406
7Recurrent bacterial skin infections (HP:0005406)3.48645375
8Pallor (HP:0000980)3.47721357
9Macrocytic anemia (HP:0001972)3.32221034
10Chronic obstructive pulmonary disease (HP:0006510)3.30874154
11Obstructive lung disease (HP:0006536)3.30874154
12Recurrent bronchitis (HP:0002837)3.27074305
13Mediastinal lymphadenopathy (HP:0100721)3.23228702
14Abnormality of macrophages (HP:0004311)3.18311088
15Chronic otitis media (HP:0000389)3.09578579
16Nasal polyposis (HP:0100582)2.99203745
17Gastrointestinal infarctions (HP:0005244)2.98683011
18Abnormality of the nasal mucosa (HP:0000433)2.98298352
19Panhypogammaglobulinemia (HP:0003139)2.84727567
20Abnormality of T cells (HP:0002843)2.84498317
21Elevated erythrocyte sedimentation rate (HP:0003565)2.81691262
22Basal cell carcinoma (HP:0002671)2.78264290
23Abnormal delayed hypersensitivity skin test (HP:0002963)2.77263105
24Abnormality of T cell physiology (HP:0011840)2.74425690
25Stomatitis (HP:0010280)2.72668802
26Vasculitis (HP:0002633)2.71656187
27Recurrent viral infections (HP:0004429)2.71342904
28Colon cancer (HP:0003003)2.65496908
29Obstructive sleep apnea (HP:0002870)2.64729048
30Recurrent gram-negative bacterial infections (HP:0005420)2.64271487
31Orchitis (HP:0100796)2.64122099
32T lymphocytopenia (HP:0005403)2.60818662
33Gastrointestinal inflammation (HP:0004386)2.60374668
34Aplastic anemia (HP:0001915)2.56570466
35Multiple enchondromatosis (HP:0005701)2.55333466
36Selective tooth agenesis (HP:0001592)2.54903168
37Amaurosis fugax (HP:0100576)2.53624915
38Oral leukoplakia (HP:0002745)2.53044944
39Pustule (HP:0200039)2.52173478
40Agammaglobulinemia (HP:0004432)2.51870426
41Gingivitis (HP:0000230)2.51420371
42Recurrent skin infections (HP:0001581)2.49034008
43Petechiae (HP:0000967)2.47804380
44Encephalitis (HP:0002383)2.46678882
45Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.45095592
46Segmental peripheral demyelination/remyelination (HP:0003481)2.44805363
47Seborrheic dermatitis (HP:0001051)2.43984229
48Abnormality of T cell number (HP:0011839)2.41585294
49Abnormality of the fingertips (HP:0001211)2.39204193
50Polygenic inheritance (HP:0010982)2.39019894
51Inflammation of the large intestine (HP:0002037)2.38604279
52Chest pain (HP:0100749)2.38303766
53Thoracic kyphosis (HP:0002942)2.35151144
54Trismus (HP:0000211)2.34334293
55Cellulitis (HP:0100658)2.33288252
56Recurrent fungal infections (HP:0002841)2.32847607
57Ependymoma (HP:0002888)2.29651965
58Prolonged bleeding time (HP:0003010)2.27658235
59Absent thumb (HP:0009777)2.27398540
60Abnormality of cells of the lymphoid lineage (HP:0012140)2.26963719
61Centrally nucleated skeletal muscle fibers (HP:0003687)2.26644660
62Hypertensive crisis (HP:0100735)2.25845925
63Verrucae (HP:0200043)2.25299458
64Papilloma (HP:0012740)2.25299458
65Microretrognathia (HP:0000308)2.25156143
66Colitis (HP:0002583)2.24605653
67Lymphoma (HP:0002665)2.24321026
68Abnormality of reticulocytes (HP:0004312)2.22291322
69Easy fatigability (HP:0003388)2.22164747
70Urticaria (HP:0001025)2.22051673
71B lymphocytopenia (HP:0010976)2.21725711
72Abnormality of B cell number (HP:0010975)2.21725711
73Lymphopenia (HP:0001888)2.19949861
74Combined immunodeficiency (HP:0005387)2.19835485
75Aplasia/Hypoplasia of the sacrum (HP:0008517)2.19539383
76Restrictive lung disease (HP:0002091)2.18950110
77Retrobulbar optic neuritis (HP:0100654)2.15859737
78Optic neuritis (HP:0100653)2.15859737
79Osteomyelitis (HP:0002754)2.15341560
80Deep palmar crease (HP:0006191)2.12937681
81Poikiloderma (HP:0001029)2.12614419
82Abnormality of the thoracic spine (HP:0100711)2.11914593
83Increased IgE level (HP:0003212)2.11261446
84Sepsis (HP:0100806)2.09275368
85Hypergammaglobulinemia (HP:0010702)2.05664018
86Myositis (HP:0100614)2.03987029
87Spontaneous hematomas (HP:0007420)2.02968757
88Viral hepatitis (HP:0006562)1.99687727
89Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.99195069
90Breast hypoplasia (HP:0003187)1.98099208
91Myelodysplasia (HP:0002863)1.96679646
92Increased IgM level (HP:0003496)1.95840890
93Birth length less than 3rd percentile (HP:0003561)1.94649866
94Slow saccadic eye movements (HP:0000514)1.94281904
95Increased cerebral lipofuscin (HP:0011813)1.94057647
96Abnormal hemoglobin (HP:0011902)1.93050502
97Pulmonary infiltrates (HP:0002113)1.92784323
98Medulloblastoma (HP:0002885)1.92516617
99Purpura (HP:0000979)1.91870785
100Meningitis (HP:0001287)1.91162918
101IgG deficiency (HP:0004315)1.90650651
102Emphysema (HP:0002097)1.90284272
103Neoplasm of the pancreas (HP:0002894)1.89663440
104Carpal bone hypoplasia (HP:0001498)1.87017695
105Severe combined immunodeficiency (HP:0004430)1.86992700
106Increased density of long bones (HP:0006392)1.86624631
107Growth hormone excess (HP:0000845)1.85684466
108Broad face (HP:0000283)1.84044654
109Impaired platelet aggregation (HP:0003540)1.83966098
110Abnormal platelet function (HP:0011869)1.83966098
111Autoimmune hemolytic anemia (HP:0001890)1.83842457
112Bronchitis (HP:0012387)1.82522994
113Interstitial pulmonary disease (HP:0006530)1.81947601
114Increased neuronal autofluorescent lipopigment (HP:0002074)1.81202499
115Leukocytosis (HP:0001974)1.80789116
116Hemorrhage of the eye (HP:0011885)1.80546743
117Hypochromic anemia (HP:0001931)1.80359621
118Hemoptysis (HP:0002105)1.80318683
119Abnormality of the anterior horn cell (HP:0006802)1.78139088
120Degeneration of anterior horn cells (HP:0002398)1.78139088
121Granulocytopenia (HP:0001913)1.77120640
122Chronic mucocutaneous candidiasis (HP:0002728)1.76515127
123Recurrent cutaneous fungal infections (HP:0011370)1.76515127
124Patellar aplasia (HP:0006443)1.76075687
125Epistaxis (HP:0000421)1.75883174
126Increased variability in muscle fiber diameter (HP:0003557)1.75764612
127Asplenia (HP:0001746)1.75487172
128Annular pancreas (HP:0001734)1.74483610
129Hyperacusis (HP:0010780)1.73139683
130Microcytic anemia (HP:0001935)1.72980995
131Malnutrition (HP:0004395)1.72676956
132Abnormality of the columella (HP:0009929)1.72004965
133Dysostosis multiplex (HP:0000943)1.71896282
134Squamous cell carcinoma (HP:0002860)1.71838772
135Increased serum ferritin (HP:0003281)1.71608577
13611 pairs of ribs (HP:0000878)1.71103429
137Aplasia/Hypoplasia of the patella (HP:0006498)1.70450779
138Abnormal number of incisors (HP:0011064)1.70389628
139Myopathic facies (HP:0002058)1.70265516
140Keratoconjunctivitis sicca (HP:0001097)1.70150055
141IgA deficiency (HP:0002720)1.69106203
142Prominent nose (HP:0000448)1.69031137
143Rhabdomyosarcoma (HP:0002859)1.67617248
144Aplasia/Hypoplasia of the spleen (HP:0010451)1.67445560
145Leukopenia (HP:0001882)1.66860813
146Skin ulcer (HP:0200042)1.64988275
147Skin tags (HP:0010609)1.64663736
148Cellular immunodeficiency (HP:0005374)1.64172726
149Eczematoid dermatitis (HP:0000976)1.63514001
150Entropion (HP:0000621)1.63419950
151Aplasia/Hypoplasia of the thymus (HP:0010515)1.62861077
152Recurrent sinusitis (HP:0011108)1.61247025
153Sparse lateral eyebrow (HP:0005338)1.61003486
154Gastrointestinal stroma tumor (HP:0100723)1.59466452
155Rectal prolapse (HP:0002035)1.58818068

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B3.87203859
2MAP4K13.77240289
3EEF2K3.44076289
4MAP3K103.10379964
5SMG12.77132690
6PKN22.70958914
7RIPK42.59302413
8NME22.55601623
9TRIB32.31754689
10BUB12.12715288
11RPS6KB22.09564744
12TLK12.08272108
13NEK21.99307553
14MAP3K131.91518794
15STK101.90241491
16ERN11.85345434
17LRRK21.83741372
18GRK61.83535545
19RPS6KA41.78700401
20FLT31.77002649
21ZAP701.71944786
22WEE11.70638876
23FES1.70507050
24TGFBR11.65649880
25CDK121.63594861
26CDC71.55607958
27TNK21.55114551
28BLK1.54192176
29BTK1.48123139
30DYRK31.47246607
31ICK1.46864418
32JAK31.45942741
33TESK21.44209944
34MARK21.35484956
35KDR1.34825196
36MAPKAPK31.34246235
37PASK1.33842128
38CDK41.32847067
39MAP2K31.29879422
40FGFR41.29607661
41SIK21.28907893
42TBK11.26723625
43TYK21.26481132
44EIF2AK11.23162136
45PIM11.22953366
46CDK71.21639250
47TXK1.19425368
48MAP3K81.18300768
49MAP3K11.15973894
50SIK31.08933551
51IKBKB1.07613523
52TGFBR21.06884233
53TSSK61.06546805
54EPHB11.06114091
55MAP3K111.05027466
56MAPK121.03133268
57SRPK11.02111052
58PRKD21.01709158
59BCKDK1.01023910
60RIPK11.00639047
61IKBKE1.00056567
62TAOK10.97154347
63CDC42BPA0.96766030
64AURKB0.94500031
65RPS6KL10.93852739
66RPS6KC10.93852739
67PAK40.93561722
68EPHA20.92965153
69CSF1R0.91980072
70SCYL20.91765636
71STK40.91182699
72MARK30.88327258
73KIT0.85891730
74ATR0.85071274
75TAOK20.83760348
76CDK190.81883942
77PDPK10.80497790
78NLK0.80073491
79ACVR1B0.79656064
80CAMKK10.79446605
81PIM20.79092469
82ITK0.78871786
83CHUK0.78082307
84PLK10.77481995
85PDK10.74699388
86MAPK70.74465464
87NEK10.74047396
88MAP2K20.73959861
89TEC0.73437348
90ILK0.73043014
91DYRK1B0.72014662
92SYK0.71810087
93KSR20.70390055
94EPHA30.69552870
95JAK10.68585920
96TTN0.68427791
97BRD40.67881913
98LCK0.67069135
99IRAK20.66883116
100TYRO30.64395133
101PTK60.63739615
102TTK0.63520890
103ALK0.63461065
104RPS6KA20.61855750
105JAK20.61030806
106IRAK30.60703803
107RPS6KA50.58661285
108CDK60.58244912
109MAP3K30.55920987
110MAPK110.54068388
111MKNK10.53647721
112RET0.53523226
113SIK10.52125617
114MTOR0.51976812
115CSK0.51334976
116CHEK10.50860191
117EIF2AK30.49058203
118PRKCQ0.48685013
119CLK10.48356447
120HCK0.48029532
121TAOK30.46239368
122MAPK40.45813438
123MAP3K60.45773537
124IRAK10.45612781
125BMX0.45263944
126CHEK20.45104891
127VRK10.44363262
128HIPK20.43529636
129IRAK40.43447072
130RPS6KA60.42968050
131FGFR30.42593611
132MST40.42460194
133MAP3K140.42162424
134LYN0.42149723
135CDK90.41977231
136RPS6KA10.41817956
137BRSK20.40821196
138CDK20.40810192
139ARAF0.40771513
140MAP3K70.40576224
141PRKCI0.40406199
142PRKCH0.36442376
143FGR0.36237458
144MAPKAPK20.35552768
145FYN0.35295726
146PRKD30.34429095

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.93924180
2DNA replication_Homo sapiens_hsa030303.75220349
3Mismatch repair_Homo sapiens_hsa034302.99968063
4Spliceosome_Homo sapiens_hsa030402.79223469
5Primary immunodeficiency_Homo sapiens_hsa053402.59670639
6Base excision repair_Homo sapiens_hsa034102.59573741
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.25910338
8Autoimmune thyroid disease_Homo sapiens_hsa053202.20896894
9Graft-versus-host disease_Homo sapiens_hsa053322.16436305
10RNA transport_Homo sapiens_hsa030132.15035152
11One carbon pool by folate_Homo sapiens_hsa006702.00996773
12RNA polymerase_Homo sapiens_hsa030201.93977663
13Homologous recombination_Homo sapiens_hsa034401.87640276
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.84058213
15Nucleotide excision repair_Homo sapiens_hsa034201.80003184
16Antigen processing and presentation_Homo sapiens_hsa046121.72279005
17Cell cycle_Homo sapiens_hsa041101.70110786
18Pyrimidine metabolism_Homo sapiens_hsa002401.65477011
19Staphylococcus aureus infection_Homo sapiens_hsa051501.62717707
20Proteasome_Homo sapiens_hsa030501.53473769
21Sulfur relay system_Homo sapiens_hsa041221.47169786
22Type I diabetes mellitus_Homo sapiens_hsa049401.45864300
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.45461445
24* Herpes simplex infection_Homo sapiens_hsa051681.43372784
25Asthma_Homo sapiens_hsa053101.42230764
26p53 signaling pathway_Homo sapiens_hsa041151.41406759
27NF-kappa B signaling pathway_Homo sapiens_hsa040641.39104624
28B cell receptor signaling pathway_Homo sapiens_hsa046621.38700174
29Acute myeloid leukemia_Homo sapiens_hsa052211.37335205
30mRNA surveillance pathway_Homo sapiens_hsa030151.32094654
31Non-homologous end-joining_Homo sapiens_hsa034501.31263281
32Measles_Homo sapiens_hsa051621.30733341
33Tuberculosis_Homo sapiens_hsa051521.28628343
34RNA degradation_Homo sapiens_hsa030181.27023594
35Intestinal immune network for IgA production_Homo sapiens_hsa046721.27021442
36Epstein-Barr virus infection_Homo sapiens_hsa051691.20044165
37Chemokine signaling pathway_Homo sapiens_hsa040621.18128935
38Endometrial cancer_Homo sapiens_hsa052131.16611290
39Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.15082166
40Fanconi anemia pathway_Homo sapiens_hsa034601.12572215
41T cell receptor signaling pathway_Homo sapiens_hsa046601.11634117
42HTLV-I infection_Homo sapiens_hsa051661.11360189
43Notch signaling pathway_Homo sapiens_hsa043301.10124294
44Cyanoamino acid metabolism_Homo sapiens_hsa004601.08385390
45Thyroid cancer_Homo sapiens_hsa052161.05522654
46Chronic myeloid leukemia_Homo sapiens_hsa052201.04002517
47Pentose phosphate pathway_Homo sapiens_hsa000301.03046933
48Renal cell carcinoma_Homo sapiens_hsa052111.02737474
49Viral carcinogenesis_Homo sapiens_hsa052031.01952324
50Small cell lung cancer_Homo sapiens_hsa052221.01276658
51Hematopoietic cell lineage_Homo sapiens_hsa046401.01007368
52Leishmaniasis_Homo sapiens_hsa051400.99622034
53Apoptosis_Homo sapiens_hsa042100.98539820
54Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.97487157
55Transcriptional misregulation in cancer_Homo sapiens_hsa052020.97089449
56Folate biosynthesis_Homo sapiens_hsa007900.94895194
57Jak-STAT signaling pathway_Homo sapiens_hsa046300.93419197
58Choline metabolism in cancer_Homo sapiens_hsa052310.93258491
59RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.91863391
60Legionellosis_Homo sapiens_hsa051340.91362024
61Malaria_Homo sapiens_hsa051440.90790091
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.88790570
63Systemic lupus erythematosus_Homo sapiens_hsa053220.88137658
64Phosphatidylinositol signaling system_Homo sapiens_hsa040700.80888988
65GnRH signaling pathway_Homo sapiens_hsa049120.80774945
66Hepatitis B_Homo sapiens_hsa051610.80338984
67Osteoclast differentiation_Homo sapiens_hsa043800.79726039
68Shigellosis_Homo sapiens_hsa051310.79536307
69Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78111329
70Influenza A_Homo sapiens_hsa051640.78012011
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77902880
72Basal transcription factors_Homo sapiens_hsa030220.77019696
73Insulin resistance_Homo sapiens_hsa049310.76996385
74Toxoplasmosis_Homo sapiens_hsa051450.76186977
75ErbB signaling pathway_Homo sapiens_hsa040120.76072345
76Adipocytokine signaling pathway_Homo sapiens_hsa049200.75082268
77Insulin signaling pathway_Homo sapiens_hsa049100.74789411
78Longevity regulating pathway - mammal_Homo sapiens_hsa042110.73723094
79Prostate cancer_Homo sapiens_hsa052150.73292474
80FoxO signaling pathway_Homo sapiens_hsa040680.73124879
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.72622656
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.70858126
83Biosynthesis of amino acids_Homo sapiens_hsa012300.67725366
84Drug metabolism - other enzymes_Homo sapiens_hsa009830.67446540
85Inositol phosphate metabolism_Homo sapiens_hsa005620.67079936
86Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.66428650
87Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.66378327
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.65909290
89Bladder cancer_Homo sapiens_hsa052190.65472587
90MAPK signaling pathway_Homo sapiens_hsa040100.63937269
91Leukocyte transendothelial migration_Homo sapiens_hsa046700.63824704
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.62541488
93Selenocompound metabolism_Homo sapiens_hsa004500.62467806
94Purine metabolism_Homo sapiens_hsa002300.62385034
95Endocytosis_Homo sapiens_hsa041440.61804950
96Glioma_Homo sapiens_hsa052140.60553639
97Pertussis_Homo sapiens_hsa051330.60406941
98Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60382776
99Glycerophospholipid metabolism_Homo sapiens_hsa005640.59912172
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59800475
101Non-small cell lung cancer_Homo sapiens_hsa052230.59151832
102MicroRNAs in cancer_Homo sapiens_hsa052060.58654538
103Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58604179
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58291122
105Central carbon metabolism in cancer_Homo sapiens_hsa052300.57293337
106Viral myocarditis_Homo sapiens_hsa054160.56967059
107Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56892939
108AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.56777669
109Prion diseases_Homo sapiens_hsa050200.55762803
110Other glycan degradation_Homo sapiens_hsa005110.55446223
111Colorectal cancer_Homo sapiens_hsa052100.52606070
112Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50530473
113Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.49408964
114Galactose metabolism_Homo sapiens_hsa000520.48839517
115African trypanosomiasis_Homo sapiens_hsa051430.48263761
116HIF-1 signaling pathway_Homo sapiens_hsa040660.48068514
117Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46788451
118Pancreatic cancer_Homo sapiens_hsa052120.46349139
119Toll-like receptor signaling pathway_Homo sapiens_hsa046200.46150245
120Glycosaminoglycan degradation_Homo sapiens_hsa005310.45931879
121Basal cell carcinoma_Homo sapiens_hsa052170.45431172
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44569823
123TNF signaling pathway_Homo sapiens_hsa046680.44317025
124Estrogen signaling pathway_Homo sapiens_hsa049150.44270559
125Cysteine and methionine metabolism_Homo sapiens_hsa002700.42629669
126Pathways in cancer_Homo sapiens_hsa052000.41884272
127Lysine degradation_Homo sapiens_hsa003100.41875839
128Platelet activation_Homo sapiens_hsa046110.41582734
129Prolactin signaling pathway_Homo sapiens_hsa049170.41577688
130Salmonella infection_Homo sapiens_hsa051320.41401832
131Amoebiasis_Homo sapiens_hsa051460.41096703
132Allograft rejection_Homo sapiens_hsa053300.39365419
133mTOR signaling pathway_Homo sapiens_hsa041500.38093915
134Hepatitis C_Homo sapiens_hsa051600.37695125
135Fructose and mannose metabolism_Homo sapiens_hsa000510.35906270
136Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.35166812
137VEGF signaling pathway_Homo sapiens_hsa043700.34769011
138Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33645987
139Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.33463012
140Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.32899674
141Neurotrophin signaling pathway_Homo sapiens_hsa047220.31885148
142Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.31437489

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