Rank | Gene Set | Z-score |
---|---|---|
1 | viral transcription (GO:0019083) | 6.61199918 |
2 | ribosomal small subunit assembly (GO:0000028) | 6.59384370 |
3 | translational termination (GO:0006415) | 6.33820914 |
4 | translational elongation (GO:0006414) | 5.62870125 |
5 | ribosomal small subunit biogenesis (GO:0042274) | 5.43736930 |
6 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.31371953 |
7 | negative regulation of cell killing (GO:0031342) | 5.31371953 |
8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.17848897 |
9 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.17542069 |
10 | protein targeting to ER (GO:0045047) | 5.04145942 |
11 | maturation of SSU-rRNA (GO:0030490) | 5.03800259 |
12 | cotranslational protein targeting to membrane (GO:0006613) | 5.00652770 |
13 | translational initiation (GO:0006413) | 4.96432573 |
14 | viral life cycle (GO:0019058) | 4.91080131 |
15 | cellular protein complex disassembly (GO:0043624) | 4.83463259 |
16 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.78990983 |
17 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.75482101 |
18 | protein localization to endoplasmic reticulum (GO:0070972) | 4.69900798 |
19 | negative thymic T cell selection (GO:0045060) | 4.45845345 |
20 | protein complex disassembly (GO:0043241) | 4.45396754 |
21 | ribosomal large subunit biogenesis (GO:0042273) | 4.39276852 |
22 | T cell selection (GO:0045058) | 4.23709459 |
23 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.20250948 |
24 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.20250948 |
25 | macromolecular complex disassembly (GO:0032984) | 4.14885546 |
26 | formation of translation preinitiation complex (GO:0001731) | 4.12334341 |
27 | positive T cell selection (GO:0043368) | 4.10932254 |
28 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.97939526 |
29 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.97939526 |
30 | modulation by symbiont of host immune response (GO:0052553) | 3.97939526 |
31 | positive regulation by symbiont of host defense response (GO:0052509) | 3.97939526 |
32 | modulation by symbiont of host defense response (GO:0052031) | 3.97939526 |
33 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.97939526 |
34 | DNA deamination (GO:0045006) | 3.95603308 |
35 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.88352370 |
36 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.83897855 |
37 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.83497196 |
38 | tolerance induction (GO:0002507) | 3.79338164 |
39 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.73645827 |
40 | leukocyte aggregation (GO:0070486) | 3.73366635 |
41 | B cell receptor signaling pathway (GO:0050853) | 3.72535582 |
42 | detection of bacterium (GO:0016045) | 3.71426166 |
43 | mannose metabolic process (GO:0006013) | 3.70493212 |
44 | mRNA catabolic process (GO:0006402) | 3.66057953 |
45 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.66055125 |
46 | DNA unwinding involved in DNA replication (GO:0006268) | 3.65776115 |
47 | response to muramyl dipeptide (GO:0032495) | 3.64699048 |
48 | RNA catabolic process (GO:0006401) | 3.55942893 |
49 | Peyers patch development (GO:0048541) | 3.52389530 |
50 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.52389530 |
51 | detection of other organism (GO:0098543) | 3.49703431 |
52 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.38725931 |
53 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.35207493 |
54 | regulation of B cell differentiation (GO:0045577) | 3.32570832 |
55 | protein targeting to membrane (GO:0006612) | 3.32248388 |
56 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.31467125 |
57 | translation (GO:0006412) | 3.21847806 |
58 | DNA strand elongation (GO:0022616) | 3.18117141 |
59 | T cell migration (GO:0072678) | 3.16800082 |
60 | negative regulation of phagocytosis (GO:0050765) | 3.13416429 |
61 | positive regulation of granulocyte differentiation (GO:0030854) | 3.12433796 |
62 | DNA replication initiation (GO:0006270) | 3.10686920 |
63 | ncRNA 3-end processing (GO:0043628) | 3.10450003 |
64 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.09970926 |
65 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.09679188 |
66 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.08787683 |
67 | response to interleukin-15 (GO:0070672) | 3.06704696 |
68 | modulation by virus of host process (GO:0019054) | 3.04664426 |
69 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.96932491 |
70 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.95497019 |
71 | rRNA processing (GO:0006364) | 2.95021966 |
72 | regulation of gamma-delta T cell activation (GO:0046643) | 2.94286711 |
73 | immunoglobulin mediated immune response (GO:0016064) | 2.93283830 |
74 | regulation of granulocyte differentiation (GO:0030852) | 2.92945114 |
75 | regulation of T cell tolerance induction (GO:0002664) | 2.92787300 |
76 | germinal center formation (GO:0002467) | 2.90247944 |
77 | response to peptidoglycan (GO:0032494) | 2.88864632 |
78 | histone H3-K36 demethylation (GO:0070544) | 2.88593138 |
79 | negative regulation of T cell mediated immunity (GO:0002710) | 2.87748831 |
80 | rRNA metabolic process (GO:0016072) | 2.85322170 |
81 | negative regulation of innate immune response (GO:0045824) | 2.84260156 |
82 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.83837760 |
83 | natural killer cell differentiation (GO:0001779) | 2.82930201 |
84 | response to laminar fluid shear stress (GO:0034616) | 2.81383257 |
85 | negative regulation of RNA splicing (GO:0033119) | 2.80935491 |
86 | positive thymic T cell selection (GO:0045059) | 2.80823913 |
87 | modulation by symbiont of host cellular process (GO:0044068) | 2.79721641 |
88 | ribosome biogenesis (GO:0042254) | 2.79513544 |
89 | IMP biosynthetic process (GO:0006188) | 2.79202849 |
90 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.79076917 |
91 | negative regulation of granulocyte differentiation (GO:0030853) | 2.78096740 |
92 | macrophage activation involved in immune response (GO:0002281) | 2.78078602 |
93 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.76970910 |
94 | protein localization to kinetochore (GO:0034501) | 2.75257345 |
95 | regulation of tolerance induction (GO:0002643) | 2.74235072 |
96 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.74044918 |
97 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.71634342 |
98 | mitotic nuclear envelope disassembly (GO:0007077) | 2.69811013 |
99 | positive regulation of Rap GTPase activity (GO:0032854) | 2.69540062 |
100 | T cell homeostasis (GO:0043029) | 2.69315381 |
101 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.66216921 |
102 | regulation of necroptotic process (GO:0060544) | 2.65148931 |
103 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.64474312 |
104 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.64474312 |
105 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.63156055 |
106 | T cell receptor signaling pathway (GO:0050852) | 2.63051178 |
107 | negative regulation of translational initiation (GO:0045947) | 2.62402444 |
108 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.62219691 |
109 | telomere maintenance via recombination (GO:0000722) | 2.61464149 |
110 | response to type I interferon (GO:0034340) | 2.61057380 |
111 | lymphocyte homeostasis (GO:0002260) | 2.60763767 |
112 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.58724574 |
113 | response to interleukin-4 (GO:0070670) | 2.58328292 |
114 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.57589856 |
115 | response to host immune response (GO:0052572) | 2.57589856 |
116 | T cell costimulation (GO:0031295) | 2.57448969 |
117 | DNA duplex unwinding (GO:0032508) | 2.57226503 |
118 | cellular response to type I interferon (GO:0071357) | 2.57105915 |
119 | type I interferon signaling pathway (GO:0060337) | 2.57105915 |
120 | neutrophil activation involved in immune response (GO:0002283) | 2.56313189 |
121 | positive regulation of histone deacetylation (GO:0031065) | 2.55594700 |
122 | defense response to protozoan (GO:0042832) | 2.54650144 |
123 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.54426708 |
124 | regulation of antigen processing and presentation (GO:0002577) | 2.54335091 |
125 | DNA geometric change (GO:0032392) | 2.54109651 |
126 | response to host (GO:0075136) | 2.53887293 |
127 | response to host defenses (GO:0052200) | 2.53887293 |
128 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.53887293 |
129 | detection of external biotic stimulus (GO:0098581) | 2.53330622 |
130 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.53286466 |
131 | IMP metabolic process (GO:0046040) | 2.53260880 |
132 | lymphocyte costimulation (GO:0031294) | 2.52878316 |
133 | nucleobase biosynthetic process (GO:0046112) | 2.52207557 |
134 | negative regulation of histone methylation (GO:0031061) | 2.49819339 |
135 | telomere maintenance via telomere lengthening (GO:0010833) | 2.49725229 |
136 | protein localization to chromosome, centromeric region (GO:0071459) | 2.47443879 |
137 | DNA replication checkpoint (GO:0000076) | 2.46420148 |
138 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.45956094 |
139 | maternal placenta development (GO:0001893) | 2.44477901 |
140 | mitotic recombination (GO:0006312) | 2.43965600 |
141 | membrane disassembly (GO:0030397) | 2.43939698 |
142 | nuclear envelope disassembly (GO:0051081) | 2.43939698 |
143 | regulation of histone H3-K9 methylation (GO:0051570) | 2.43760036 |
144 | spliceosomal snRNP assembly (GO:0000387) | 2.42272123 |
145 | NIK/NF-kappaB signaling (GO:0038061) | 2.41009869 |
146 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.39511897 |
147 | T cell apoptotic process (GO:0070231) | 2.38607335 |
148 | cellular component biogenesis (GO:0044085) | 2.38207766 |
149 | regulation of translational fidelity (GO:0006450) | 2.37609815 |
150 | morphogenesis of an endothelium (GO:0003159) | 2.37155951 |
151 | endothelial tube morphogenesis (GO:0061154) | 2.37155951 |
152 | thymic T cell selection (GO:0045061) | 2.37153393 |
153 | dosage compensation (GO:0007549) | 2.36538033 |
154 | mRNA splicing, via spliceosome (GO:0000398) | 2.36438472 |
155 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.36438472 |
156 | ribosome assembly (GO:0042255) | 2.35960952 |
157 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.35590084 |
158 | RNA splicing, via transesterification reactions (GO:0000375) | 2.35564290 |
159 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.33903959 |
160 | regulation of gene silencing by miRNA (GO:0060964) | 2.33903959 |
161 | regulation of gene silencing by RNA (GO:0060966) | 2.33903959 |
162 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.33616624 |
163 | heterochromatin organization (GO:0070828) | 2.30941811 |
164 | pseudouridine synthesis (GO:0001522) | 2.30061678 |
165 | regulation of translation in response to stress (GO:0043555) | 2.28260072 |
166 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.26520414 |
167 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.26520414 |
168 | trophectodermal cell differentiation (GO:0001829) | 2.26371898 |
169 | purine nucleobase biosynthetic process (GO:0009113) | 2.23960212 |
170 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.22912953 |
171 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.22414694 |
172 | negative T cell selection (GO:0043383) | 2.19899471 |
173 | positive regulation of B cell differentiation (GO:0045579) | 2.18860994 |
174 | cellular response to interleukin-4 (GO:0071353) | 2.18766797 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.83252487 |
2 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.48246024 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.37515784 |
4 | MYC_22102868_ChIP-Seq_BL_Human | 3.02576815 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.84652810 |
6 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.72421664 |
7 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.57769921 |
8 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.54847189 |
9 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.36875626 |
10 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.36213381 |
11 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.24748615 |
12 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.23969058 |
13 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.21223003 |
14 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.18845021 |
15 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.16060517 |
16 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.11386771 |
17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.09461915 |
18 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.00694755 |
19 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.98531137 |
20 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.93476003 |
21 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.83767046 |
22 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.79254134 |
23 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.77572861 |
24 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.77096061 |
25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.73600552 |
26 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.73311673 |
27 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.71535870 |
28 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69266576 |
29 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.66959041 |
30 | * CIITA_25753668_ChIP-Seq_RAJI_Human | 1.66741471 |
31 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.66712106 |
32 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.64871946 |
33 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.63722272 |
34 | MAF_26560356_Chip-Seq_TH1_Human | 1.63356105 |
35 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.62030321 |
36 | P68_20966046_ChIP-Seq_HELA_Human | 1.61846034 |
37 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.60462596 |
38 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.59644620 |
39 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57768932 |
40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.57528547 |
41 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.56967831 |
42 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.55468673 |
43 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.55195529 |
44 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.54091261 |
45 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.53536934 |
46 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.51696060 |
47 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.51395543 |
48 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.50992089 |
49 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.50399982 |
50 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.50371009 |
51 | UTX_26944678_Chip-Seq_JUKART_Human | 1.49234173 |
52 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.48687493 |
53 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.46972080 |
54 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.46929685 |
55 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.46082671 |
56 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.46053969 |
57 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.44719272 |
58 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.44524676 |
59 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.44465488 |
60 | KDM2B_26808549_Chip-Seq_K562_Human | 1.44045870 |
61 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.43438475 |
62 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42824633 |
63 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.42035506 |
64 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.41904962 |
65 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.41828913 |
66 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40191886 |
67 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.39788299 |
68 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.39786023 |
69 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.39150379 |
70 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.35976844 |
71 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.35387182 |
72 | SPI1_23127762_ChIP-Seq_K562_Human | 1.35386895 |
73 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.34361158 |
74 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34092107 |
75 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.33678167 |
76 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.33369213 |
77 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.32126459 |
78 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.30920399 |
79 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.30862411 |
80 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.30065639 |
81 | * MAF_26560356_Chip-Seq_TH2_Human | 1.29454158 |
82 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.29254932 |
83 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.29070862 |
84 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.28740067 |
85 | * MYB_26560356_Chip-Seq_TH2_Human | 1.28057635 |
86 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.27603966 |
87 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.27044369 |
88 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.27007588 |
89 | * MYB_26560356_Chip-Seq_TH1_Human | 1.26770000 |
90 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.26532129 |
91 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.26459187 |
92 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.26447904 |
93 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.25245106 |
94 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.24661650 |
95 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.22114153 |
96 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.21724861 |
97 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.21133973 |
98 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.20487437 |
99 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.20395300 |
100 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.20323443 |
101 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.19953893 |
102 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.17705126 |
103 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.17599970 |
104 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.16104142 |
105 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.15963845 |
106 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.15645966 |
107 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.15376375 |
108 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.14461662 |
109 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.14116089 |
110 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.14057044 |
111 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.13664629 |
112 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.13095408 |
113 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.12793600 |
114 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.12747188 |
115 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.10715918 |
116 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.10547150 |
117 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.10198080 |
118 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.10089013 |
119 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.09938075 |
120 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.09937546 |
121 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.09880819 |
122 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.09797095 |
123 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.09341490 |
124 | * CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.09052239 |
125 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.08989114 |
126 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.08117389 |
127 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.07787700 |
128 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.07574087 |
129 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.07064289 |
130 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.05776204 |
131 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05014342 |
132 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.04803650 |
133 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.04398364 |
134 | GATA1_19941826_ChIP-Seq_K562_Human | 1.04009742 |
135 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.02710512 |
136 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.02584403 |
137 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.02278534 |
138 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.01485203 |
139 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.01326658 |
140 | * CTCF_21964334_Chip-Seq_Bcells_Human | 1.01104813 |
141 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.01063581 |
142 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.00695767 |
143 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.00621062 |
144 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.00285508 |
145 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.00157350 |
146 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.99475951 |
147 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.99129553 |
148 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.99030627 |
149 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.99025272 |
150 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.98389988 |
151 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.97965005 |
152 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.97965005 |
153 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.97965005 |
154 | * NCOR1_26117541_ChIP-Seq_K562_Human | 0.96772969 |
155 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.96020449 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 3.15870696 |
2 | MP0003763_abnormal_thymus_physiology | 2.80945334 |
3 | MP0002396_abnormal_hematopoietic_system | 2.76826829 |
4 | MP0004957_abnormal_blastocyst_morpholog | 2.67503692 |
5 | MP0000685_abnormal_immune_system | 2.57574241 |
6 | MP0003111_abnormal_nucleus_morphology | 2.47392702 |
7 | MP0003077_abnormal_cell_cycle | 2.42442011 |
8 | MP0010094_abnormal_chromosome_stability | 2.40376780 |
9 | MP0001835_abnormal_antigen_presentation | 2.20925327 |
10 | MP0010352_gastrointestinal_tract_polyps | 2.15545722 |
11 | MP0005451_abnormal_body_composition | 2.10943330 |
12 | MP0001800_abnormal_humoral_immune | 2.07119538 |
13 | MP0004808_abnormal_hematopoietic_stem | 2.04347624 |
14 | MP0004381_abnormal_hair_follicle | 2.02548820 |
15 | MP0002398_abnormal_bone_marrow | 1.98617349 |
16 | MP0009333_abnormal_splenocyte_physiolog | 1.95292757 |
17 | MP0000490_abnormal_crypts_of | 1.90721976 |
18 | MP0008007_abnormal_cellular_replicative | 1.83808795 |
19 | MP0005671_abnormal_response_to | 1.80296818 |
20 | MP0000703_abnormal_thymus_morphology | 1.78189861 |
21 | MP0002722_abnormal_immune_system | 1.77888586 |
22 | MP0005058_abnormal_lysosome_morphology | 1.72919209 |
23 | MP0000689_abnormal_spleen_morphology | 1.72182020 |
24 | MP0008058_abnormal_DNA_repair | 1.70383989 |
25 | MP0001545_abnormal_hematopoietic_system | 1.70188168 |
26 | MP0005397_hematopoietic_system_phenotyp | 1.70188168 |
27 | MP0009278_abnormal_bone_marrow | 1.68325854 |
28 | MP0008057_abnormal_DNA_replication | 1.66699680 |
29 | MP0002452_abnormal_antigen_presenting | 1.65276258 |
30 | MP0001790_abnormal_immune_system | 1.63367162 |
31 | MP0005387_immune_system_phenotype | 1.63367162 |
32 | MP0002420_abnormal_adaptive_immunity | 1.62970406 |
33 | MP0001873_stomach_inflammation | 1.62645952 |
34 | MP0002166_altered_tumor_susceptibility | 1.61362614 |
35 | MP0000716_abnormal_immune_system | 1.61280946 |
36 | MP0001819_abnormal_immune_cell | 1.60587542 |
37 | MP0003436_decreased_susceptibility_to | 1.59173509 |
38 | MP0002723_abnormal_immune_serum | 1.57803248 |
39 | MP0002009_preneoplasia | 1.56837070 |
40 | MP0003172_abnormal_lysosome_physiology | 1.55892495 |
41 | MP0002429_abnormal_blood_cell | 1.55179363 |
42 | MP0010155_abnormal_intestine_physiology | 1.54430821 |
43 | MP0001533_abnormal_skeleton_physiology | 1.50556954 |
44 | MP0000350_abnormal_cell_proliferation | 1.49750958 |
45 | MP0004185_abnormal_adipocyte_glucose | 1.49169728 |
46 | MP0002405_respiratory_system_inflammati | 1.46403192 |
47 | MP0002019_abnormal_tumor_incidence | 1.45209862 |
48 | MP0005000_abnormal_immune_tolerance | 1.44199460 |
49 | MP0008260_abnormal_autophagy | 1.44176248 |
50 | MP0001730_embryonic_growth_arrest | 1.39989763 |
51 | MP0005025_abnormal_response_to | 1.38631713 |
52 | MP0003866_abnormal_defecation | 1.34527725 |
53 | MP0004947_skin_inflammation | 1.30643139 |
54 | MP0001851_eye_inflammation | 1.30170584 |
55 | MP0000465_gastrointestinal_hemorrhage | 1.30126028 |
56 | MP0009785_altered_susceptibility_to | 1.27808702 |
57 | MP0005666_abnormal_adipose_tissue | 1.27665437 |
58 | MP0003303_peritoneal_inflammation | 1.26900066 |
59 | MP0003786_premature_aging | 1.26753939 |
60 | MP0000858_altered_metastatic_potential | 1.25520100 |
61 | MP0002132_abnormal_respiratory_system | 1.25242972 |
62 | MP0006082_CNS_inflammation | 1.24797734 |
63 | MP0005023_abnormal_wound_healing | 1.24041144 |
64 | MP0001853_heart_inflammation | 1.23711548 |
65 | MP0002998_abnormal_bone_remodeling | 1.22775431 |
66 | MP0003300_gastrointestinal_ulcer | 1.22174500 |
67 | MP0005076_abnormal_cell_differentiation | 1.20992468 |
68 | MP0003705_abnormal_hypodermis_morpholog | 1.20592364 |
69 | MP0002796_impaired_skin_barrier | 1.20435609 |
70 | MP0010307_abnormal_tumor_latency | 1.20378603 |
71 | MP0000313_abnormal_cell_death | 1.18601998 |
72 | MP0002006_tumorigenesis | 1.17761452 |
73 | MP0001348_abnormal_lacrimal_gland | 1.16917801 |
74 | MP0004858_abnormal_nervous_system | 1.16451833 |
75 | MP0008932_abnormal_embryonic_tissue | 1.11381960 |
76 | MP0002080_prenatal_lethality | 1.10519077 |
77 | MP0003183_abnormal_peptide_metabolism | 1.10019552 |
78 | MP0001697_abnormal_embryo_size | 1.08200151 |
79 | MP0001672_abnormal_embryogenesis/_devel | 1.07863845 |
80 | MP0005380_embryogenesis_phenotype | 1.07863845 |
81 | MP0005310_abnormal_salivary_gland | 1.07182532 |
82 | MP0005464_abnormal_platelet_physiology | 1.06877148 |
83 | MP0001663_abnormal_digestive_system | 1.04929405 |
84 | MP0003984_embryonic_growth_retardation | 1.04496056 |
85 | MP0002088_abnormal_embryonic_growth/wei | 1.04154938 |
86 | MP0002086_abnormal_extraembryonic_tissu | 1.03981420 |
87 | MP0003566_abnormal_cell_adhesion | 1.03557895 |
88 | MP0005075_abnormal_melanosome_morpholog | 1.00064077 |
89 | MP0001845_abnormal_inflammatory_respons | 0.99330944 |
90 | MP0000477_abnormal_intestine_morphology | 0.99182643 |
91 | MP0000678_abnormal_parathyroid_gland | 0.99084605 |
92 | MP0003567_abnormal_fetal_cardiomyocyte | 0.96852835 |
93 | MP0004264_abnormal_extraembryonic_tissu | 0.96348655 |
94 | MP0004197_abnormal_fetal_growth/weight/ | 0.95556065 |
95 | MP0006054_spinal_hemorrhage | 0.94942378 |
96 | MP0004130_abnormal_muscle_cell | 0.92856431 |
97 | MP0002085_abnormal_embryonic_tissue | 0.89891765 |
98 | MP0002084_abnormal_developmental_patter | 0.87577756 |
99 | MP0005501_abnormal_skin_physiology | 0.85904959 |
100 | MP0005375_adipose_tissue_phenotype | 0.85779867 |
101 | MP0003453_abnormal_keratinocyte_physiol | 0.83290234 |
102 | MP0005390_skeleton_phenotype | 0.82681184 |
103 | MP0001849_ear_inflammation | 0.81303719 |
104 | MP0002148_abnormal_hypersensitivity_rea | 0.80973563 |
105 | MP0003724_increased_susceptibility_to | 0.79981003 |
106 | MP0003091_abnormal_cell_migration | 0.79172756 |
107 | MP0002653_abnormal_ependyma_morphology | 0.78668418 |
108 | MP0010030_abnormal_orbit_morphology | 0.78411198 |
109 | MP0008995_early_reproductive_senescence | 0.78238787 |
110 | MP0005381_digestive/alimentary_phenotyp | 0.76964994 |
111 | MP0009840_abnormal_foam_cell | 0.76634617 |
112 | MP0000733_abnormal_muscle_development | 0.76397885 |
113 | MP0002419_abnormal_innate_immunity | 0.76050037 |
114 | MP0003448_altered_tumor_morphology | 0.75939475 |
115 | MP0001216_abnormal_epidermal_layer | 0.74913470 |
116 | MP0005409_darkened_coat_color | 0.73409751 |
117 | MP0009379_abnormal_foot_pigmentation | 0.73119625 |
118 | MP0003279_aneurysm | 0.73061824 |
119 | MP0004510_myositis | 0.72452272 |
120 | MP0002254_reproductive_system_inflammat | 0.71615892 |
121 | MP0009931_abnormal_skin_appearance | 0.69221862 |
122 | MP0000681_abnormal_thyroid_gland | 0.69158950 |
123 | MP0002249_abnormal_larynx_morphology | 0.69100249 |
124 | MP0003828_pulmonary_edema | 0.68078480 |
125 | MP0005166_decreased_susceptibility_to | 0.66989136 |
126 | MP0010234_abnormal_vibrissa_follicle | 0.66879611 |
127 | MP0003191_abnormal_cellular_cholesterol | 0.65178463 |
128 | MP0008469_abnormal_protein_level | 0.64638426 |
129 | MP0000598_abnormal_liver_morphology | 0.64307733 |
130 | MP0000249_abnormal_blood_vessel | 0.63505197 |
131 | MP0002933_joint_inflammation | 0.61964838 |
132 | MP0002138_abnormal_hepatobiliary_system | 0.61742559 |
133 | MP0009115_abnormal_fat_cell | 0.60521589 |
134 | MP0003795_abnormal_bone_structure | 0.58446126 |
135 | MP0008961_abnormal_basal_metabolism | 0.57383537 |
136 | MP0008004_abnormal_stomach_pH | 0.53142046 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.99679415 |
2 | Reticulocytopenia (HP:0001896) | 4.87976206 |
3 | Abnormal number of erythroid precursors (HP:0012131) | 4.60302207 |
4 | Thrombocytosis (HP:0001894) | 3.87529888 |
5 | Recurrent abscess formation (HP:0002722) | 3.53777615 |
6 | IgM deficiency (HP:0002850) | 3.49254406 |
7 | Recurrent bacterial skin infections (HP:0005406) | 3.48645375 |
8 | Pallor (HP:0000980) | 3.47721357 |
9 | Macrocytic anemia (HP:0001972) | 3.32221034 |
10 | Chronic obstructive pulmonary disease (HP:0006510) | 3.30874154 |
11 | Obstructive lung disease (HP:0006536) | 3.30874154 |
12 | Recurrent bronchitis (HP:0002837) | 3.27074305 |
13 | Mediastinal lymphadenopathy (HP:0100721) | 3.23228702 |
14 | Abnormality of macrophages (HP:0004311) | 3.18311088 |
15 | Chronic otitis media (HP:0000389) | 3.09578579 |
16 | Nasal polyposis (HP:0100582) | 2.99203745 |
17 | Gastrointestinal infarctions (HP:0005244) | 2.98683011 |
18 | Abnormality of the nasal mucosa (HP:0000433) | 2.98298352 |
19 | Panhypogammaglobulinemia (HP:0003139) | 2.84727567 |
20 | Abnormality of T cells (HP:0002843) | 2.84498317 |
21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.81691262 |
22 | Basal cell carcinoma (HP:0002671) | 2.78264290 |
23 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.77263105 |
24 | Abnormality of T cell physiology (HP:0011840) | 2.74425690 |
25 | Stomatitis (HP:0010280) | 2.72668802 |
26 | Vasculitis (HP:0002633) | 2.71656187 |
27 | Recurrent viral infections (HP:0004429) | 2.71342904 |
28 | Colon cancer (HP:0003003) | 2.65496908 |
29 | Obstructive sleep apnea (HP:0002870) | 2.64729048 |
30 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.64271487 |
31 | Orchitis (HP:0100796) | 2.64122099 |
32 | T lymphocytopenia (HP:0005403) | 2.60818662 |
33 | Gastrointestinal inflammation (HP:0004386) | 2.60374668 |
34 | Aplastic anemia (HP:0001915) | 2.56570466 |
35 | Multiple enchondromatosis (HP:0005701) | 2.55333466 |
36 | Selective tooth agenesis (HP:0001592) | 2.54903168 |
37 | Amaurosis fugax (HP:0100576) | 2.53624915 |
38 | Oral leukoplakia (HP:0002745) | 2.53044944 |
39 | Pustule (HP:0200039) | 2.52173478 |
40 | Agammaglobulinemia (HP:0004432) | 2.51870426 |
41 | Gingivitis (HP:0000230) | 2.51420371 |
42 | Recurrent skin infections (HP:0001581) | 2.49034008 |
43 | Petechiae (HP:0000967) | 2.47804380 |
44 | Encephalitis (HP:0002383) | 2.46678882 |
45 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.45095592 |
46 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.44805363 |
47 | Seborrheic dermatitis (HP:0001051) | 2.43984229 |
48 | Abnormality of T cell number (HP:0011839) | 2.41585294 |
49 | Abnormality of the fingertips (HP:0001211) | 2.39204193 |
50 | Polygenic inheritance (HP:0010982) | 2.39019894 |
51 | Inflammation of the large intestine (HP:0002037) | 2.38604279 |
52 | Chest pain (HP:0100749) | 2.38303766 |
53 | Thoracic kyphosis (HP:0002942) | 2.35151144 |
54 | Trismus (HP:0000211) | 2.34334293 |
55 | Cellulitis (HP:0100658) | 2.33288252 |
56 | Recurrent fungal infections (HP:0002841) | 2.32847607 |
57 | Ependymoma (HP:0002888) | 2.29651965 |
58 | Prolonged bleeding time (HP:0003010) | 2.27658235 |
59 | Absent thumb (HP:0009777) | 2.27398540 |
60 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.26963719 |
61 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.26644660 |
62 | Hypertensive crisis (HP:0100735) | 2.25845925 |
63 | Verrucae (HP:0200043) | 2.25299458 |
64 | Papilloma (HP:0012740) | 2.25299458 |
65 | Microretrognathia (HP:0000308) | 2.25156143 |
66 | Colitis (HP:0002583) | 2.24605653 |
67 | Lymphoma (HP:0002665) | 2.24321026 |
68 | Abnormality of reticulocytes (HP:0004312) | 2.22291322 |
69 | Easy fatigability (HP:0003388) | 2.22164747 |
70 | Urticaria (HP:0001025) | 2.22051673 |
71 | B lymphocytopenia (HP:0010976) | 2.21725711 |
72 | Abnormality of B cell number (HP:0010975) | 2.21725711 |
73 | Lymphopenia (HP:0001888) | 2.19949861 |
74 | Combined immunodeficiency (HP:0005387) | 2.19835485 |
75 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.19539383 |
76 | Restrictive lung disease (HP:0002091) | 2.18950110 |
77 | Retrobulbar optic neuritis (HP:0100654) | 2.15859737 |
78 | Optic neuritis (HP:0100653) | 2.15859737 |
79 | Osteomyelitis (HP:0002754) | 2.15341560 |
80 | Deep palmar crease (HP:0006191) | 2.12937681 |
81 | Poikiloderma (HP:0001029) | 2.12614419 |
82 | Abnormality of the thoracic spine (HP:0100711) | 2.11914593 |
83 | Increased IgE level (HP:0003212) | 2.11261446 |
84 | Sepsis (HP:0100806) | 2.09275368 |
85 | Hypergammaglobulinemia (HP:0010702) | 2.05664018 |
86 | Myositis (HP:0100614) | 2.03987029 |
87 | Spontaneous hematomas (HP:0007420) | 2.02968757 |
88 | Viral hepatitis (HP:0006562) | 1.99687727 |
89 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.99195069 |
90 | Breast hypoplasia (HP:0003187) | 1.98099208 |
91 | Myelodysplasia (HP:0002863) | 1.96679646 |
92 | Increased IgM level (HP:0003496) | 1.95840890 |
93 | Birth length less than 3rd percentile (HP:0003561) | 1.94649866 |
94 | Slow saccadic eye movements (HP:0000514) | 1.94281904 |
95 | Increased cerebral lipofuscin (HP:0011813) | 1.94057647 |
96 | Abnormal hemoglobin (HP:0011902) | 1.93050502 |
97 | Pulmonary infiltrates (HP:0002113) | 1.92784323 |
98 | Medulloblastoma (HP:0002885) | 1.92516617 |
99 | Purpura (HP:0000979) | 1.91870785 |
100 | Meningitis (HP:0001287) | 1.91162918 |
101 | IgG deficiency (HP:0004315) | 1.90650651 |
102 | Emphysema (HP:0002097) | 1.90284272 |
103 | Neoplasm of the pancreas (HP:0002894) | 1.89663440 |
104 | Carpal bone hypoplasia (HP:0001498) | 1.87017695 |
105 | Severe combined immunodeficiency (HP:0004430) | 1.86992700 |
106 | Increased density of long bones (HP:0006392) | 1.86624631 |
107 | Growth hormone excess (HP:0000845) | 1.85684466 |
108 | Broad face (HP:0000283) | 1.84044654 |
109 | Impaired platelet aggregation (HP:0003540) | 1.83966098 |
110 | Abnormal platelet function (HP:0011869) | 1.83966098 |
111 | Autoimmune hemolytic anemia (HP:0001890) | 1.83842457 |
112 | Bronchitis (HP:0012387) | 1.82522994 |
113 | Interstitial pulmonary disease (HP:0006530) | 1.81947601 |
114 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.81202499 |
115 | Leukocytosis (HP:0001974) | 1.80789116 |
116 | Hemorrhage of the eye (HP:0011885) | 1.80546743 |
117 | Hypochromic anemia (HP:0001931) | 1.80359621 |
118 | Hemoptysis (HP:0002105) | 1.80318683 |
119 | Abnormality of the anterior horn cell (HP:0006802) | 1.78139088 |
120 | Degeneration of anterior horn cells (HP:0002398) | 1.78139088 |
121 | Granulocytopenia (HP:0001913) | 1.77120640 |
122 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.76515127 |
123 | Recurrent cutaneous fungal infections (HP:0011370) | 1.76515127 |
124 | Patellar aplasia (HP:0006443) | 1.76075687 |
125 | Epistaxis (HP:0000421) | 1.75883174 |
126 | Increased variability in muscle fiber diameter (HP:0003557) | 1.75764612 |
127 | Asplenia (HP:0001746) | 1.75487172 |
128 | Annular pancreas (HP:0001734) | 1.74483610 |
129 | Hyperacusis (HP:0010780) | 1.73139683 |
130 | Microcytic anemia (HP:0001935) | 1.72980995 |
131 | Malnutrition (HP:0004395) | 1.72676956 |
132 | Abnormality of the columella (HP:0009929) | 1.72004965 |
133 | Dysostosis multiplex (HP:0000943) | 1.71896282 |
134 | Squamous cell carcinoma (HP:0002860) | 1.71838772 |
135 | Increased serum ferritin (HP:0003281) | 1.71608577 |
136 | 11 pairs of ribs (HP:0000878) | 1.71103429 |
137 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.70450779 |
138 | Abnormal number of incisors (HP:0011064) | 1.70389628 |
139 | Myopathic facies (HP:0002058) | 1.70265516 |
140 | Keratoconjunctivitis sicca (HP:0001097) | 1.70150055 |
141 | IgA deficiency (HP:0002720) | 1.69106203 |
142 | Prominent nose (HP:0000448) | 1.69031137 |
143 | Rhabdomyosarcoma (HP:0002859) | 1.67617248 |
144 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.67445560 |
145 | Leukopenia (HP:0001882) | 1.66860813 |
146 | Skin ulcer (HP:0200042) | 1.64988275 |
147 | Skin tags (HP:0010609) | 1.64663736 |
148 | Cellular immunodeficiency (HP:0005374) | 1.64172726 |
149 | Eczematoid dermatitis (HP:0000976) | 1.63514001 |
150 | Entropion (HP:0000621) | 1.63419950 |
151 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.62861077 |
152 | Recurrent sinusitis (HP:0011108) | 1.61247025 |
153 | Sparse lateral eyebrow (HP:0005338) | 1.61003486 |
154 | Gastrointestinal stroma tumor (HP:0100723) | 1.59466452 |
155 | Rectal prolapse (HP:0002035) | 1.58818068 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PRPF4B | 3.87203859 |
2 | MAP4K1 | 3.77240289 |
3 | EEF2K | 3.44076289 |
4 | MAP3K10 | 3.10379964 |
5 | SMG1 | 2.77132690 |
6 | PKN2 | 2.70958914 |
7 | RIPK4 | 2.59302413 |
8 | NME2 | 2.55601623 |
9 | TRIB3 | 2.31754689 |
10 | BUB1 | 2.12715288 |
11 | RPS6KB2 | 2.09564744 |
12 | TLK1 | 2.08272108 |
13 | NEK2 | 1.99307553 |
14 | MAP3K13 | 1.91518794 |
15 | STK10 | 1.90241491 |
16 | ERN1 | 1.85345434 |
17 | LRRK2 | 1.83741372 |
18 | GRK6 | 1.83535545 |
19 | RPS6KA4 | 1.78700401 |
20 | FLT3 | 1.77002649 |
21 | ZAP70 | 1.71944786 |
22 | WEE1 | 1.70638876 |
23 | FES | 1.70507050 |
24 | TGFBR1 | 1.65649880 |
25 | CDK12 | 1.63594861 |
26 | CDC7 | 1.55607958 |
27 | TNK2 | 1.55114551 |
28 | BLK | 1.54192176 |
29 | BTK | 1.48123139 |
30 | DYRK3 | 1.47246607 |
31 | ICK | 1.46864418 |
32 | JAK3 | 1.45942741 |
33 | TESK2 | 1.44209944 |
34 | MARK2 | 1.35484956 |
35 | KDR | 1.34825196 |
36 | MAPKAPK3 | 1.34246235 |
37 | PASK | 1.33842128 |
38 | CDK4 | 1.32847067 |
39 | MAP2K3 | 1.29879422 |
40 | FGFR4 | 1.29607661 |
41 | SIK2 | 1.28907893 |
42 | TBK1 | 1.26723625 |
43 | TYK2 | 1.26481132 |
44 | EIF2AK1 | 1.23162136 |
45 | PIM1 | 1.22953366 |
46 | CDK7 | 1.21639250 |
47 | TXK | 1.19425368 |
48 | MAP3K8 | 1.18300768 |
49 | MAP3K1 | 1.15973894 |
50 | SIK3 | 1.08933551 |
51 | IKBKB | 1.07613523 |
52 | TGFBR2 | 1.06884233 |
53 | TSSK6 | 1.06546805 |
54 | EPHB1 | 1.06114091 |
55 | MAP3K11 | 1.05027466 |
56 | MAPK12 | 1.03133268 |
57 | SRPK1 | 1.02111052 |
58 | PRKD2 | 1.01709158 |
59 | BCKDK | 1.01023910 |
60 | RIPK1 | 1.00639047 |
61 | IKBKE | 1.00056567 |
62 | TAOK1 | 0.97154347 |
63 | CDC42BPA | 0.96766030 |
64 | AURKB | 0.94500031 |
65 | RPS6KL1 | 0.93852739 |
66 | RPS6KC1 | 0.93852739 |
67 | PAK4 | 0.93561722 |
68 | EPHA2 | 0.92965153 |
69 | CSF1R | 0.91980072 |
70 | SCYL2 | 0.91765636 |
71 | STK4 | 0.91182699 |
72 | MARK3 | 0.88327258 |
73 | KIT | 0.85891730 |
74 | ATR | 0.85071274 |
75 | TAOK2 | 0.83760348 |
76 | CDK19 | 0.81883942 |
77 | PDPK1 | 0.80497790 |
78 | NLK | 0.80073491 |
79 | ACVR1B | 0.79656064 |
80 | CAMKK1 | 0.79446605 |
81 | PIM2 | 0.79092469 |
82 | ITK | 0.78871786 |
83 | CHUK | 0.78082307 |
84 | PLK1 | 0.77481995 |
85 | PDK1 | 0.74699388 |
86 | MAPK7 | 0.74465464 |
87 | NEK1 | 0.74047396 |
88 | MAP2K2 | 0.73959861 |
89 | TEC | 0.73437348 |
90 | ILK | 0.73043014 |
91 | DYRK1B | 0.72014662 |
92 | SYK | 0.71810087 |
93 | KSR2 | 0.70390055 |
94 | EPHA3 | 0.69552870 |
95 | JAK1 | 0.68585920 |
96 | TTN | 0.68427791 |
97 | BRD4 | 0.67881913 |
98 | LCK | 0.67069135 |
99 | IRAK2 | 0.66883116 |
100 | TYRO3 | 0.64395133 |
101 | PTK6 | 0.63739615 |
102 | TTK | 0.63520890 |
103 | ALK | 0.63461065 |
104 | RPS6KA2 | 0.61855750 |
105 | JAK2 | 0.61030806 |
106 | IRAK3 | 0.60703803 |
107 | RPS6KA5 | 0.58661285 |
108 | CDK6 | 0.58244912 |
109 | MAP3K3 | 0.55920987 |
110 | MAPK11 | 0.54068388 |
111 | MKNK1 | 0.53647721 |
112 | RET | 0.53523226 |
113 | SIK1 | 0.52125617 |
114 | MTOR | 0.51976812 |
115 | CSK | 0.51334976 |
116 | CHEK1 | 0.50860191 |
117 | EIF2AK3 | 0.49058203 |
118 | PRKCQ | 0.48685013 |
119 | CLK1 | 0.48356447 |
120 | HCK | 0.48029532 |
121 | TAOK3 | 0.46239368 |
122 | MAPK4 | 0.45813438 |
123 | MAP3K6 | 0.45773537 |
124 | IRAK1 | 0.45612781 |
125 | BMX | 0.45263944 |
126 | CHEK2 | 0.45104891 |
127 | VRK1 | 0.44363262 |
128 | HIPK2 | 0.43529636 |
129 | IRAK4 | 0.43447072 |
130 | RPS6KA6 | 0.42968050 |
131 | FGFR3 | 0.42593611 |
132 | MST4 | 0.42460194 |
133 | MAP3K14 | 0.42162424 |
134 | LYN | 0.42149723 |
135 | CDK9 | 0.41977231 |
136 | RPS6KA1 | 0.41817956 |
137 | BRSK2 | 0.40821196 |
138 | CDK2 | 0.40810192 |
139 | ARAF | 0.40771513 |
140 | MAP3K7 | 0.40576224 |
141 | PRKCI | 0.40406199 |
142 | PRKCH | 0.36442376 |
143 | FGR | 0.36237458 |
144 | MAPKAPK2 | 0.35552768 |
145 | FYN | 0.35295726 |
146 | PRKD3 | 0.34429095 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.93924180 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.75220349 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 2.99968063 |
4 | Spliceosome_Homo sapiens_hsa03040 | 2.79223469 |
5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.59670639 |
6 | Base excision repair_Homo sapiens_hsa03410 | 2.59573741 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.25910338 |
8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.20896894 |
9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.16436305 |
10 | RNA transport_Homo sapiens_hsa03013 | 2.15035152 |
11 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.00996773 |
12 | RNA polymerase_Homo sapiens_hsa03020 | 1.93977663 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 1.87640276 |
14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.84058213 |
15 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.80003184 |
16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.72279005 |
17 | Cell cycle_Homo sapiens_hsa04110 | 1.70110786 |
18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.65477011 |
19 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.62717707 |
20 | Proteasome_Homo sapiens_hsa03050 | 1.53473769 |
21 | Sulfur relay system_Homo sapiens_hsa04122 | 1.47169786 |
22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.45864300 |
23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.45461445 |
24 | * Herpes simplex infection_Homo sapiens_hsa05168 | 1.43372784 |
25 | Asthma_Homo sapiens_hsa05310 | 1.42230764 |
26 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.41406759 |
27 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.39104624 |
28 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.38700174 |
29 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.37335205 |
30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.32094654 |
31 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.31263281 |
32 | Measles_Homo sapiens_hsa05162 | 1.30733341 |
33 | Tuberculosis_Homo sapiens_hsa05152 | 1.28628343 |
34 | RNA degradation_Homo sapiens_hsa03018 | 1.27023594 |
35 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.27021442 |
36 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.20044165 |
37 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.18128935 |
38 | Endometrial cancer_Homo sapiens_hsa05213 | 1.16611290 |
39 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.15082166 |
40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.12572215 |
41 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.11634117 |
42 | HTLV-I infection_Homo sapiens_hsa05166 | 1.11360189 |
43 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.10124294 |
44 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.08385390 |
45 | Thyroid cancer_Homo sapiens_hsa05216 | 1.05522654 |
46 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.04002517 |
47 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.03046933 |
48 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.02737474 |
49 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.01952324 |
50 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.01276658 |
51 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01007368 |
52 | Leishmaniasis_Homo sapiens_hsa05140 | 0.99622034 |
53 | Apoptosis_Homo sapiens_hsa04210 | 0.98539820 |
54 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97487157 |
55 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.97089449 |
56 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.94895194 |
57 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.93419197 |
58 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.93258491 |
59 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.91863391 |
60 | Legionellosis_Homo sapiens_hsa05134 | 0.91362024 |
61 | Malaria_Homo sapiens_hsa05144 | 0.90790091 |
62 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.88790570 |
63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.88137658 |
64 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.80888988 |
65 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.80774945 |
66 | Hepatitis B_Homo sapiens_hsa05161 | 0.80338984 |
67 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.79726039 |
68 | Shigellosis_Homo sapiens_hsa05131 | 0.79536307 |
69 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.78111329 |
70 | Influenza A_Homo sapiens_hsa05164 | 0.78012011 |
71 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.77902880 |
72 | Basal transcription factors_Homo sapiens_hsa03022 | 0.77019696 |
73 | Insulin resistance_Homo sapiens_hsa04931 | 0.76996385 |
74 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.76186977 |
75 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.76072345 |
76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.75082268 |
77 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.74789411 |
78 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.73723094 |
79 | Prostate cancer_Homo sapiens_hsa05215 | 0.73292474 |
80 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.73124879 |
81 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.72622656 |
82 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.70858126 |
83 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.67725366 |
84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.67446540 |
85 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.67079936 |
86 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.66428650 |
87 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.66378327 |
88 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.65909290 |
89 | Bladder cancer_Homo sapiens_hsa05219 | 0.65472587 |
90 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.63937269 |
91 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.63824704 |
92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.62541488 |
93 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62467806 |
94 | Purine metabolism_Homo sapiens_hsa00230 | 0.62385034 |
95 | Endocytosis_Homo sapiens_hsa04144 | 0.61804950 |
96 | Glioma_Homo sapiens_hsa05214 | 0.60553639 |
97 | Pertussis_Homo sapiens_hsa05133 | 0.60406941 |
98 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.60382776 |
99 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.59912172 |
100 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.59800475 |
101 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.59151832 |
102 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.58654538 |
103 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58604179 |
104 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.58291122 |
105 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.57293337 |
106 | Viral myocarditis_Homo sapiens_hsa05416 | 0.56967059 |
107 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56892939 |
108 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.56777669 |
109 | Prion diseases_Homo sapiens_hsa05020 | 0.55762803 |
110 | Other glycan degradation_Homo sapiens_hsa00511 | 0.55446223 |
111 | Colorectal cancer_Homo sapiens_hsa05210 | 0.52606070 |
112 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.50530473 |
113 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.49408964 |
114 | Galactose metabolism_Homo sapiens_hsa00052 | 0.48839517 |
115 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.48263761 |
116 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.48068514 |
117 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.46788451 |
118 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.46349139 |
119 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.46150245 |
120 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.45931879 |
121 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.45431172 |
122 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.44569823 |
123 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.44317025 |
124 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.44270559 |
125 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42629669 |
126 | Pathways in cancer_Homo sapiens_hsa05200 | 0.41884272 |
127 | Lysine degradation_Homo sapiens_hsa00310 | 0.41875839 |
128 | Platelet activation_Homo sapiens_hsa04611 | 0.41582734 |
129 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.41577688 |
130 | Salmonella infection_Homo sapiens_hsa05132 | 0.41401832 |
131 | Amoebiasis_Homo sapiens_hsa05146 | 0.41096703 |
132 | Allograft rejection_Homo sapiens_hsa05330 | 0.39365419 |
133 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.38093915 |
134 | Hepatitis C_Homo sapiens_hsa05160 | 0.37695125 |
135 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.35906270 |
136 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.35166812 |
137 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.34769011 |
138 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.33645987 |
139 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.33463012 |
140 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.32899674 |
141 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.31885148 |
142 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.31437489 |