GLYAT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)8.60210372
2omega-hydroxylase P450 pathway (GO:0097267)8.48632250
3L-phenylalanine catabolic process (GO:0006559)7.63736864
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.63736864
5L-phenylalanine metabolic process (GO:0006558)7.33673472
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.33673472
7aromatic amino acid family catabolic process (GO:0009074)7.02728284
8tryptophan catabolic process (GO:0006569)6.49000701
9indole-containing compound catabolic process (GO:0042436)6.49000701
10indolalkylamine catabolic process (GO:0046218)6.49000701
11glyoxylate metabolic process (GO:0046487)6.36222313
12tryptophan metabolic process (GO:0006568)6.11277305
13kynurenine metabolic process (GO:0070189)6.08980194
14oxidative demethylation (GO:0070989)5.95839479
15ethanol metabolic process (GO:0006067)5.93646669
16bile acid biosynthetic process (GO:0006699)5.89581558
17cysteine metabolic process (GO:0006534)5.85880974
18blood coagulation, intrinsic pathway (GO:0007597)5.69902766
19triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.55395229
20lysine metabolic process (GO:0006553)5.45914039
21lysine catabolic process (GO:0006554)5.45914039
22urea cycle (GO:0000050)5.40551715
23urea metabolic process (GO:0019627)5.40551715
24serine family amino acid catabolic process (GO:0009071)5.38138450
25phenylpropanoid metabolic process (GO:0009698)5.36022011
26sulfur amino acid catabolic process (GO:0000098)5.34189501
27fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.25569856
28alpha-linolenic acid metabolic process (GO:0036109)5.22694550
29S-adenosylmethionine metabolic process (GO:0046500)5.21440878
30homocysteine metabolic process (GO:0050667)5.20951145
31aromatic amino acid family metabolic process (GO:0009072)5.12081399
32complement activation, alternative pathway (GO:0006957)5.00337685
33nitrogen cycle metabolic process (GO:0071941)4.99892149
34negative regulation of fibrinolysis (GO:0051918)4.99219396
35bile acid metabolic process (GO:0008206)4.93487360
36peptidyl-glutamic acid carboxylation (GO:0017187)4.93210745
37protein carboxylation (GO:0018214)4.93210745
38regulation of protein activation cascade (GO:2000257)4.91642028
39high-density lipoprotein particle remodeling (GO:0034375)4.88411631
40urate metabolic process (GO:0046415)4.86938423
41regulation of plasminogen activation (GO:0010755)4.84106858
42amino-acid betaine metabolic process (GO:0006577)4.83921111
43regulation of fibrinolysis (GO:0051917)4.81124951
44alpha-amino acid catabolic process (GO:1901606)4.80759271
45drug transmembrane transport (GO:0006855)4.74237979
46protein activation cascade (GO:0072376)4.71181816
47tyrosine metabolic process (GO:0006570)4.70566302
48drug catabolic process (GO:0042737)4.65831437
49regulation of complement activation (GO:0030449)4.61990128
50indolalkylamine metabolic process (GO:0006586)4.60415083
51cellular ketone body metabolic process (GO:0046950)4.55775319
52response to mercury ion (GO:0046689)4.51222007
53amine catabolic process (GO:0009310)4.48842360
54cellular biogenic amine catabolic process (GO:0042402)4.48842360
55cellular amino acid catabolic process (GO:0009063)4.47532732
56complement activation (GO:0006956)4.46986720
57negative regulation of hemostasis (GO:1900047)4.42238856
58negative regulation of blood coagulation (GO:0030195)4.42238856
59positive regulation of triglyceride lipase activity (GO:0061365)4.39651137
60positive regulation of lipoprotein lipase activity (GO:0051006)4.39651137
61regulation of triglyceride catabolic process (GO:0010896)4.38051641
62cellular modified amino acid catabolic process (GO:0042219)4.37905681
63cellular glucuronidation (GO:0052695)4.37460762
64coenzyme catabolic process (GO:0009109)4.37192162
65glutamate metabolic process (GO:0006536)4.36823729
66* serine family amino acid metabolic process (GO:0009069)4.34517754
67negative regulation of protein activation cascade (GO:2000258)4.30944648
68benzene-containing compound metabolic process (GO:0042537)4.30600791
69exogenous drug catabolic process (GO:0042738)4.28940932
70alkaloid metabolic process (GO:0009820)4.26033520
71complement activation, classical pathway (GO:0006958)4.25835104
72triglyceride homeostasis (GO:0070328)4.25552378
73acylglycerol homeostasis (GO:0055090)4.25552378
74acute-phase response (GO:0006953)4.25390448
75negative regulation of cholesterol transport (GO:0032375)4.25116880
76negative regulation of sterol transport (GO:0032372)4.25116880
77reverse cholesterol transport (GO:0043691)4.24000380
78serine family amino acid biosynthetic process (GO:0009070)4.22712236
79regulation of cholesterol esterification (GO:0010872)4.22502832
80plasma lipoprotein particle remodeling (GO:0034369)4.18992326
81protein-lipid complex remodeling (GO:0034368)4.18992326
82macromolecular complex remodeling (GO:0034367)4.18992326
83aldehyde catabolic process (GO:0046185)4.18496149
84ethanol oxidation (GO:0006069)4.15363471
85bile acid and bile salt transport (GO:0015721)4.14041552
86short-chain fatty acid metabolic process (GO:0046459)4.13746650
87opsonization (GO:0008228)4.11648616
88regulation of humoral immune response (GO:0002920)4.11513331
89dicarboxylic acid biosynthetic process (GO:0043650)4.06550677
90negative regulation of coagulation (GO:0050819)4.03512791
91imidazole-containing compound metabolic process (GO:0052803)4.02697560
92* glycine metabolic process (GO:0006544)4.01581313
93glucuronate metabolic process (GO:0019585)4.00440367
94uronic acid metabolic process (GO:0006063)4.00440367
95negative regulation of wound healing (GO:0061045)3.96280819
96phospholipid efflux (GO:0033700)3.96056636
97acetyl-CoA metabolic process (GO:0006084)3.95808313
98ketone body metabolic process (GO:1902224)3.94104899
99aspartate family amino acid catabolic process (GO:0009068)3.93871974
100organic acid catabolic process (GO:0016054)3.93153675
101carboxylic acid catabolic process (GO:0046395)3.93153675
102drug transport (GO:0015893)3.93121169
103arginine metabolic process (GO:0006525)3.91401836
104plasma lipoprotein particle clearance (GO:0034381)3.84104651
105disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.81578769
106killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.81578769
107positive regulation of blood coagulation (GO:0030194)3.77555330
108positive regulation of hemostasis (GO:1900048)3.77555330
109negative regulation of complement activation (GO:0045916)3.76926304
1102-oxoglutarate metabolic process (GO:0006103)3.71560846
111regulation of bile acid biosynthetic process (GO:0070857)3.71508970
112fatty acid beta-oxidation (GO:0006635)3.67504938
113fatty acid oxidation (GO:0019395)3.65792130
114cofactor catabolic process (GO:0051187)3.64342543
115fibrinolysis (GO:0042730)3.64278260
116cholesterol efflux (GO:0033344)3.63667105
117regulation of cholesterol homeostasis (GO:2000188)3.63320673
118hormone catabolic process (GO:0042447)3.62974486
119NAD biosynthetic process (GO:0009435)3.62316564
120monocarboxylic acid catabolic process (GO:0072329)3.62296726
121carnitine metabolic process (GO:0009437)3.61499900
122pyridine nucleotide biosynthetic process (GO:0019363)3.60414019
123nicotinamide nucleotide biosynthetic process (GO:0019359)3.60414019
124negative regulation of lipase activity (GO:0060192)3.59836011
125lipid oxidation (GO:0034440)3.58953451
126aminoglycoside antibiotic metabolic process (GO:0030647)3.56003116
127flavonoid metabolic process (GO:0009812)3.54908086
128drug metabolic process (GO:0017144)3.54626434
129xenobiotic catabolic process (GO:0042178)3.52971689
130low-density lipoprotein particle remodeling (GO:0034374)3.52789756
131response to nitrosative stress (GO:0051409)3.52468800
132primary alcohol metabolic process (GO:0034308)3.52458253
133cytolysis (GO:0019835)3.52244875
134valine metabolic process (GO:0006573)3.51931465
135* xenobiotic metabolic process (GO:0006805)3.48528412
136positive regulation of coagulation (GO:0050820)3.47668737
137sodium-independent organic anion transport (GO:0043252)3.42796094
138amino acid salvage (GO:0043102)3.41598903
139L-methionine salvage (GO:0071267)3.41598903
140L-methionine biosynthetic process (GO:0071265)3.41598903
141doxorubicin metabolic process (GO:0044598)3.38849708

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.31677935
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.13831924
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.91647619
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.39723758
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.10287738
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.87555838
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.79947521
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.97814529
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.96674998
10HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.16578553
11TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.12693271
12TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.11345087
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.7448702
14POU3F2_20337985_ChIP-ChIP_501MEL_Human1.64293890
15FOXA2_19822575_ChIP-Seq_HepG2_Human1.58294682
16CLOCK_20551151_ChIP-Seq_293T_Human1.54241858
17HNF4A_19822575_ChIP-Seq_HepG2_Human1.47522170
18HTT_18923047_ChIP-ChIP_STHdh_Human1.38551522
19PIAS1_25552417_ChIP-Seq_VCAP_Human1.37566929
20STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.32852638
21* BCAT_22108803_ChIP-Seq_LS180_Human1.32005701
22IGF1R_20145208_ChIP-Seq_DFB_Human1.31842036
23GATA1_22025678_ChIP-Seq_K562_Human1.31801355
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.28157076
25GBX2_23144817_ChIP-Seq_PC3_Human1.25139815
26ER_23166858_ChIP-Seq_MCF-7_Human1.20323053
27IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.17332390
28RXRA_24833708_ChIP-Seq_LIVER_Mouse1.17258673
29NFE2_27457419_Chip-Seq_LIVER_Mouse1.13314976
30EZH2_27294783_Chip-Seq_NPCs_Mouse1.12375977
31ESR1_20079471_ChIP-ChIP_T-47D_Human1.11598791
32AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11348312
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.11201887
34THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.11131141
35ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.10692497
36CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.09575130
37PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06356095
38PHF8_20622853_ChIP-Seq_HELA_Human1.03465017
39HNFA_21074721_ChIP-Seq_CACO-2_Human1.03069364
40SOX2_27498859_Chip-Seq_STOMACH_Mouse0.99255500
41IRF8_22096565_ChIP-ChIP_GC-B_Human0.99043434
42RARG_19884340_ChIP-ChIP_MEFs_Mouse0.98917523
43CRX_20693478_ChIP-Seq_RETINA_Mouse0.96696352
44CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96435538
45SUZ12_27294783_Chip-Seq_NPCs_Mouse0.96057266
46ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.96023143
47ETV2_25802403_ChIP-Seq_MESCs_Mouse0.95468970
48IRF1_19129219_ChIP-ChIP_H3396_Human0.94027686
49GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.91285186
50GATA4_25053715_ChIP-Seq_YYC3_Human0.89839956
51TRIM28_21343339_ChIP-Seq_HEK293_Human0.89750416
52NFYA_21822215_ChIP-Seq_K562_Human0.89466251
53KLF5_20875108_ChIP-Seq_MESCs_Mouse0.88228449
54PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.87843306
55UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87322948
56PCGF2_27294783_Chip-Seq_NPCs_Mouse0.86737506
57KAP1_22055183_ChIP-Seq_ESCs_Mouse0.84903235
58OCT4_21477851_ChIP-Seq_ESCs_Mouse0.84701536
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84376025
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.84143970
61CBP_20019798_ChIP-Seq_JUKART_Human0.84143970
62FOXA1_21572438_ChIP-Seq_LNCaP_Human0.83219369
63GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.82715030
64ESR1_21235772_ChIP-Seq_MCF-7_Human0.82710487
65NANOG_19829295_ChIP-Seq_ESCs_Human0.81982726
66SOX2_19829295_ChIP-Seq_ESCs_Human0.81982726
67* TCF4_22108803_ChIP-Seq_LS180_Human0.81707571
68Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.81235535
69GATA6_21074721_ChIP-Seq_CACO-2_Human0.80085572
70STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.79435782
71AUTS2_25519132_ChIP-Seq_293T-REX_Human0.79292814
72ESR1_15608294_ChIP-ChIP_MCF-7_Human0.78817822
73ETV1_20927104_ChIP-Seq_GIST48_Human0.77611756
74EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.77175369
75RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.76413144
76ESR2_21235772_ChIP-Seq_MCF-7_Human0.76344072
77EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.75230227
78BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.75107813
79NFYB_21822215_ChIP-Seq_K562_Human0.75089722
80ZFP57_27257070_Chip-Seq_ESCs_Mouse0.74852669
81STAT3_23295773_ChIP-Seq_U87_Human0.74680839
82CTBP1_25329375_ChIP-Seq_LNCAP_Human0.74472830
83OCT4_18555785_Chip-Seq_ESCs_Mouse0.74185289
84FOXA1_27270436_Chip-Seq_PROSTATE_Human0.74013612
85FOXA1_25329375_ChIP-Seq_VCAP_Human0.74013612
86CBX2_22325352_ChIP-Seq_293T-Rex_Human0.73329506
87SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.72790542
88PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.71782675
89AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.71638610
90TP53_18474530_ChIP-ChIP_U2OS_Human0.71278882
91CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.70918913
92MYC_19829295_ChIP-Seq_ESCs_Human0.70122880
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.69939914
94SALL4_18804426_ChIP-ChIP_XEN_Mouse0.69922897
95RARA_24833708_ChIP-Seq_LIVER_Mouse0.69716608
96TCF4_18268006_ChIP-ChIP_LS174T_Human0.69522682
97SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.69297353
98RUNX1_27457419_Chip-Seq_LIVER_Mouse0.68706611
99NRF2_20460467_ChIP-Seq_MEFs_Mouse0.68486328
100NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.68486328
101EGR1_19032775_ChIP-ChIP_M12_Human0.68451925
102ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.68173498
103SOX2_21211035_ChIP-Seq_LN229_Human0.67464602
104P53_22387025_ChIP-Seq_ESCs_Mouse0.67249933
105CDX2_20551321_ChIP-Seq_CACO-2_Human0.66697587
106PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.66194904
107NANOG_18555785_Chip-Seq_ESCs_Mouse0.66175295
108RAD21_21589869_ChIP-Seq_MESCs_Mouse0.66091665
109BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.66063391
110NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.63115429
111STAT3_1855785_ChIP-Seq_MESCs_Mouse0.62790432
112CEBPB_22108803_ChIP-Seq_LS180_Human0.60622097
113AR_20517297_ChIP-Seq_VCAP_Human0.60078467
114RARB_24833708_ChIP-Seq_LIVER_Mouse0.59293952
115MYC_19915707_ChIP-ChIP_AK7_Human0.56338162
116FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.55834129
117LXR_22292898_ChIP-Seq_THP-1_Human0.53288570
118ESET_19884257_ChIP-Seq_ESCs_Mouse0.52531396
119* STAT1_17558387_ChIP-Seq_HELA_Human0.52475601
120PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.51082887
121FOXA1_25552417_ChIP-Seq_VCAP_Human0.50815862
122GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.50666298
123ZNF263_19887448_ChIP-Seq_K562_Human0.49635754
124PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.48301761
125* CBP_21632823_ChIP-Seq_H3396_Human0.48136361
126FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.46995017
127TAF2_19829295_ChIP-Seq_ESCs_Human0.46355014
128FOXO3_23340844_ChIP-Seq_DLD1_Human0.46177115
129GATA6_25053715_ChIP-Seq_YYC3_Human0.45720708
130PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.45710216
131CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.44931159
132FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.44596375
133SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.43399504
134EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.43280458
135E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.42526311
136PPAR_26484153_Chip-Seq_NCI-H1993_Human0.42168077
137CDX2_22108803_ChIP-Seq_LS180_Human0.42158296
138TAF15_26573619_Chip-Seq_HEK293_Human0.42152408
139P53_21459846_ChIP-Seq_SAOS-2_Human0.41606418
140FOXH1_21741376_ChIP-Seq_EPCs_Human0.40800055
141CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.39575200
142STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.39099133
143SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.39036783
144GATA1_19941827_ChIP-Seq_MEL_Mouse0.38588222
145* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.38063601
146FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.37675247
147GATA2_19941826_ChIP-Seq_K562_Human0.37541242
148FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.37451011
149SOX2_20726797_ChIP-Seq_SW620_Human0.36725489
150NCOR_22424771_ChIP-Seq_293T_Human0.36553813
151ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.36099073
152ERG_20517297_ChIP-Seq_VCAP_Human0.36057587
153SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.35478173
154P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.35228003
155LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.34644688

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.17689724
2MP0005360_urolithiasis7.99119877
3MP0005085_abnormal_gallbladder_physiolo6.15777956
4MP0005365_abnormal_bile_salt5.90143038
5MP0008875_abnormal_xenobiotic_pharmacok5.06598526
6MP0003806_abnormal_nucleotide_metabolis4.10745844
7MP0003252_abnormal_bile_duct3.93476737
8MP0005332_abnormal_amino_acid3.29128510
9MP0010329_abnormal_lipoprotein_level3.25530136
10MP0003195_calcinosis3.22983714
11MP0009840_abnormal_foam_cell2.77617369
12MP0004019_abnormal_vitamin_homeostasis2.77586985
13MP0005083_abnormal_biliary_tract2.71711539
14MP0001666_abnormal_nutrient_absorption2.43302378
15MP0002138_abnormal_hepatobiliary_system2.40829371
16MP0003191_abnormal_cellular_cholesterol2.11291666
17MP0000609_abnormal_liver_physiology2.01425594
18MP0002118_abnormal_lipid_homeostasis1.99129483
19MP0005319_abnormal_enzyme/_coenzyme1.87151969
20MP0009643_abnormal_urine_homeostasis1.77021470
21MP0001764_abnormal_homeostasis1.72532609
22MP0003868_abnormal_feces_composition1.70596129
23MP0005584_abnormal_enzyme/coenzyme_acti1.67048475
24MP0003186_abnormal_redox_activity1.53562540
25MP0005451_abnormal_body_composition1.47049455
26MP0005636_abnormal_mineral_homeostasis1.37455729
27MP0009697_abnormal_copulation1.35451621
28MP0004043_abnormal_pH_regulation1.20950257
29MP0003011_delayed_dark_adaptation1.14522908
30MP0000598_abnormal_liver_morphology1.13401313
31MP0009764_decreased_sensitivity_to1.13019796
32MP0002132_abnormal_respiratory_system1.10160817
33MP0005647_abnormal_sex_gland1.06406241
34MP0001756_abnormal_urination1.03251514
35MP0003656_abnormal_erythrocyte_physiolo1.01888454
36MP0005084_abnormal_gallbladder_morpholo0.97748143
37MP0006036_abnormal_mitochondrial_physio0.96223015
38MP0002876_abnormal_thyroid_physiology0.95711573
39MP0009763_increased_sensitivity_to0.93047900
40MP0008469_abnormal_protein_level0.91308522
41MP0002136_abnormal_kidney_physiology0.91140500
42MP0003705_abnormal_hypodermis_morpholog0.90431452
43MP0009642_abnormal_blood_homeostasis0.90126780
44MP0005670_abnormal_white_adipose0.89533702
45MP0000604_amyloidosis0.89097659
46MP0005408_hypopigmentation0.88180229
47MP0002254_reproductive_system_inflammat0.79390853
48MP0001765_abnormal_ion_homeostasis0.77896387
49MP0005535_abnormal_body_temperature0.77478167
50MP0005220_abnormal_exocrine_pancreas0.76104270
51MP0005375_adipose_tissue_phenotype0.75782656
52MP0005376_homeostasis/metabolism_phenot0.75154471
53MP0009765_abnormal_xenobiotic_induced0.74980196
54MP0002078_abnormal_glucose_homeostasis0.74300178
55MP0010368_abnormal_lymphatic_system0.71554300
56MP0001661_extended_life_span0.67739005
57MP0005187_abnormal_penis_morphology0.67013170
58MP0002928_abnormal_bile_duct0.65698978
59MP0002971_abnormal_brown_adipose0.63883923
60MP0002282_abnormal_trachea_morphology0.62594307
61MP0005334_abnormal_fat_pad0.60994369
62MP0005266_abnormal_metabolism0.59441462
63MP0006035_abnormal_mitochondrial_morpho0.59019837
64MP0003690_abnormal_glial_cell0.56530010
65MP0009053_abnormal_anal_canal0.54399112
66MP0004130_abnormal_muscle_cell0.54066639
67MP0005058_abnormal_lysosome_morphology0.53671438
68MP0001915_intracranial_hemorrhage0.53638304
69MP0005395_other_phenotype0.53619831
70MP0003638_abnormal_response/metabolism_0.52465942
71MP0003879_abnormal_hair_cell0.52115151
72MP0003329_amyloid_beta_deposits0.51557051
73MP0003724_increased_susceptibility_to0.49162907
74MP0000230_abnormal_systemic_arterial0.47615749
75MP0002168_other_aberrant_phenotype0.46324628
76MP0005167_abnormal_blood-brain_barrier0.46038624
77MP0004782_abnormal_surfactant_physiolog0.44422280
78MP0005666_abnormal_adipose_tissue0.43236202
79MP0003953_abnormal_hormone_level0.42698995
80MP0005448_abnormal_energy_balance0.42098713
81MP0000639_abnormal_adrenal_gland0.41826043
82MP0005464_abnormal_platelet_physiology0.41202714
83MP0003718_maternal_effect0.40182630
84MP0000538_abnormal_urinary_bladder0.40143026
85MP0005166_decreased_susceptibility_to0.39848707
86MP0008873_increased_physiological_sensi0.39675289
87MP0008874_decreased_physiological_sensi0.39639566
88MP0002135_abnormal_kidney_morphology0.37898409
89MP0002909_abnormal_adrenal_gland0.37721446
90MP0005164_abnormal_response_to0.37536712
91MP0003436_decreased_susceptibility_to0.37526325
92MP0005452_abnormal_adipose_tissue0.37448238
93MP0003075_altered_response_to0.37219683
94MP0002796_impaired_skin_barrier0.36394890
95MP0008872_abnormal_physiological_respon0.36272991
96MP0009672_abnormal_birth_weight0.35564331
97MP0009785_altered_susceptibility_to0.35166067
98MP0006082_CNS_inflammation0.31870535
99MP0002822_catalepsy0.31811559
100MP0001845_abnormal_inflammatory_respons0.31751724
101MP0004381_abnormal_hair_follicle0.31668108
102MP0002332_abnormal_exercise_endurance0.31174032
103MP0004264_abnormal_extraembryonic_tissu0.30961699
104MP0004883_abnormal_blood_vessel0.30079435
105MP0005248_abnormal_Harderian_gland0.29638868
106MP0010386_abnormal_urinary_bladder0.29267717
107MP0000003_abnormal_adipose_tissue0.29078757
108MP0002837_dystrophic_cardiac_calcinosis0.28584558
109MP0009115_abnormal_fat_cell0.28551185
110MP0000579_abnormal_nail_morphology0.28538041
111MP0009384_cardiac_valve_regurgitation0.28382296
112MP0005551_abnormal_eye_electrophysiolog0.27293619
113MP0003959_abnormal_lean_body0.25307022
114MP0002638_abnormal_pupillary_reflex0.24782725
115MP0002970_abnormal_white_adipose0.24612719
116MP0002249_abnormal_larynx_morphology0.23650790
117MP0000249_abnormal_blood_vessel0.23617113
118MP0002069_abnormal_eating/drinking_beha0.23023175
119MP0004147_increased_porphyrin_level0.22713497
120MP0002090_abnormal_vision0.21927444
121MP0002295_abnormal_pulmonary_circulatio0.21822993
122MP0001851_eye_inflammation0.21572956
123MP0001545_abnormal_hematopoietic_system0.20769231
124MP0005397_hematopoietic_system_phenotyp0.20769231
125MP0005379_endocrine/exocrine_gland_phen0.20714485

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.02860663
2Intrahepatic cholestasis (HP:0001406)6.78770258
3Deep venous thrombosis (HP:0002625)6.41216783
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.16696888
5Xanthomatosis (HP:0000991)5.80606026
6Prolonged partial thromboplastin time (HP:0003645)5.68740656
7Hypobetalipoproteinemia (HP:0003563)5.51562363
8Complement deficiency (HP:0004431)4.87161109
9Hyperlipoproteinemia (HP:0010980)4.83526876
10Abnormality of glutamine family amino acid metabolism (HP:0010902)4.80279868
11Hyperammonemia (HP:0001987)4.63090280
12Hyperglycinemia (HP:0002154)4.61785772
13Hyperglycinuria (HP:0003108)4.61473978
14Ketosis (HP:0001946)4.49007893
15Abnormality of glycine metabolism (HP:0010895)4.38820637
16Abnormality of serine family amino acid metabolism (HP:0010894)4.38820637
17Joint hemorrhage (HP:0005261)4.35749798
18Abnormality of aspartate family amino acid metabolism (HP:0010899)4.33267607
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.23993915
20Hypolipoproteinemia (HP:0010981)4.07398776
21Epidermoid cyst (HP:0200040)4.03629211
22Abnormality of the common coagulation pathway (HP:0010990)3.89057597
23Fat malabsorption (HP:0002630)3.88883802
24Abnormality of methionine metabolism (HP:0010901)3.87824000
25Gout (HP:0001997)3.87297729
26Abnormality of pyrimidine metabolism (HP:0004353)3.74804893
27Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.73154479
28Hypoglycemic coma (HP:0001325)3.71367783
29Abnormality of fatty-acid metabolism (HP:0004359)3.66084349
30Abnormality of nucleobase metabolism (HP:0010932)3.56990451
31Conjugated hyperbilirubinemia (HP:0002908)3.56754930
32Abnormality of complement system (HP:0005339)3.53025436
33Hypoalphalipoproteinemia (HP:0003233)3.53014766
34Ketoacidosis (HP:0001993)3.50983059
35Abnormality of purine metabolism (HP:0004352)3.48083230
36Delayed CNS myelination (HP:0002188)3.35266217
37Nephritis (HP:0000123)3.32539769
38Abnormality of the intrinsic pathway (HP:0010989)3.29904902
39Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.21323209
40Abnormality of serum amino acid levels (HP:0003112)3.19843122
41Hyperbilirubinemia (HP:0002904)3.15320114
42Hypercholesterolemia (HP:0003124)3.07531591
43Metabolic acidosis (HP:0001942)2.98975930
44Steatorrhea (HP:0002570)2.96635590
45Hepatocellular carcinoma (HP:0001402)2.94653128
46Vascular calcification (HP:0004934)2.92718327
47Proximal tubulopathy (HP:0000114)2.92556631
48Generalized aminoaciduria (HP:0002909)2.92218342
49Alkalosis (HP:0001948)2.86026531
50Dicarboxylic aciduria (HP:0003215)2.85767406
51Abnormality of dicarboxylic acid metabolism (HP:0010995)2.85767406
52Fair hair (HP:0002286)2.82322771
53Lethargy (HP:0001254)2.82276165
54Osteomalacia (HP:0002749)2.77064311
55Neonatal hypoglycemia (HP:0001998)2.74707758
56Hyperuricemia (HP:0002149)2.71213779
57Increased purine levels (HP:0004368)2.71213779
58Hyperphosphaturia (HP:0003109)2.69687438
59Systemic lupus erythematosus (HP:0002725)2.67374843
60Reduced antithrombin III activity (HP:0001976)2.61701052
61Myocardial infarction (HP:0001658)2.59057372
62Cardiovascular calcification (HP:0011915)2.58605582
63Increased circulating renin level (HP:0000848)2.56393082
64Gingival bleeding (HP:0000225)2.54038614
65Spontaneous abortion (HP:0005268)2.51280109
66Spastic diplegia (HP:0001264)2.49559521
67Neonatal onset (HP:0003623)2.47168479
68Hypochromic microcytic anemia (HP:0004840)2.47021622
69Irritability (HP:0000737)2.46934680
70Cerebral edema (HP:0002181)2.45833513
71Hemorrhage of the eye (HP:0011885)2.45778246
72Malnutrition (HP:0004395)2.45567369
73Enlarged kidneys (HP:0000105)2.45457713
74Skin nodule (HP:0200036)2.41948980
75Vomiting (HP:0002013)2.38393348
76Abnormality of urine glucose concentration (HP:0011016)2.38271102
77Glycosuria (HP:0003076)2.38271102
78Rickets (HP:0002748)2.36191280
79Hydroxyprolinuria (HP:0003080)2.35232816
80Abnormality of proline metabolism (HP:0010907)2.35232816
81Sensorimotor neuropathy (HP:0007141)2.32514834
82Metabolic alkalosis (HP:0200114)2.31864801
83Pulmonary embolism (HP:0002204)2.28789583
84Hypoglycemic seizures (HP:0002173)2.27669473
85Mitral stenosis (HP:0001718)2.25297246
86Recurrent gram-negative bacterial infections (HP:0005420)2.23453536
87Pancreatitis (HP:0001733)2.20294540
88Late onset (HP:0003584)2.18037729
89Abnormal enzyme/coenzyme activity (HP:0012379)2.17661414
90Glomerulonephritis (HP:0000099)2.13920157
91Abnormality of vitamin metabolism (HP:0100508)2.11426037
92Abnormal gallbladder morphology (HP:0012437)2.10888275
93Abnormal urine phosphate concentration (HP:0012599)2.09330488
94Purpura (HP:0000979)2.06818448
95Cholelithiasis (HP:0001081)2.06282494
96Opisthotonus (HP:0002179)2.03172327
97Abnormal gallbladder physiology (HP:0012438)2.02295311
98Cholecystitis (HP:0001082)2.02295311
99Esophageal varix (HP:0002040)2.01067968
100Acanthocytosis (HP:0001927)2.00527816
101Hypophosphatemic rickets (HP:0004912)1.99465932
102Arthropathy (HP:0003040)1.98191494
103Hypomagnesemia (HP:0002917)1.96525564
104Generalized hypopigmentation of hair (HP:0011358)1.95826483
105Brushfield spots (HP:0001088)1.95294994
106Nephrolithiasis (HP:0000787)1.94726988
107Hypokalemic alkalosis (HP:0001949)1.94535412
108Abnormality of alkaline phosphatase activity (HP:0004379)1.94082662
109Thrombophlebitis (HP:0004418)1.93272734
110Renal cortical cysts (HP:0000803)1.93030654
111Elevated alkaline phosphatase (HP:0003155)1.89960672
112Abnormal urine output (HP:0012590)1.87417156
113Menorrhagia (HP:0000132)1.86302808
114Abnormal cartilage morphology (HP:0002763)1.86101287
115Nausea (HP:0002018)1.83753608
116Confusion (HP:0001289)1.83690751
117Amyloidosis (HP:0011034)1.83348243
118Hyperactive renin-angiotensin system (HP:0000841)1.80730236
119Abnormality of the gallbladder (HP:0005264)1.80249522
120Hypertriglyceridemia (HP:0002155)1.79798172
121Potter facies (HP:0002009)1.70977004
122Facial shape deformation (HP:0011334)1.70977004
123Cerebral palsy (HP:0100021)1.68461203
124Increased mean platelet volume (HP:0011877)1.65698385
125Impaired platelet aggregation (HP:0003540)1.65235452
126Abnormal platelet function (HP:0011869)1.65235452
127Blue irides (HP:0000635)1.63518399

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.23283593
2FGFR44.27069078
3ERN13.92546108
4SIK13.74792523
5WNK43.23062923
6WNK32.80328550
7ERBB42.78816138
8INSRR2.72709751
9TAOK32.50432179
10OXSR12.47572733
11MAP4K22.29937955
12MST1R2.23241740
13CAMKK22.17293354
14STK38L2.03249848
15MAP2K42.00153852
16MAPK111.83288566
17BMPR1B1.65749913
18LATS11.64036184
19ACVR1B1.58178980
20PIK3CG1.55299821
21ABL21.50177237
22TYK21.44866040
23FLT31.44820877
24PKN21.43256934
25PINK11.42045038
26NEK91.37744106
27PIK3CA1.37110103
28MAP3K141.31843345
29FRK1.29723080
30BCR1.27785822
31PTK61.25974096
32MAP3K71.20373256
33GRK61.14429900
34TRIB31.12097420
35DAPK21.09389735
36IRAK31.07895416
37JAK21.07346725
38PRKAA21.06823191
39KDR1.05263188
40SGK2231.04667564
41SGK4941.04667564
42STK391.03283092
43MAP3K31.03164692
44NTRK31.03045470
45TNK21.01609861
46MAP2K31.00239728
47SGK30.99512569
48TRIM280.99132868
49ARAF0.98094194
50FGFR20.97046704
51PRKG10.96839304
52GRK50.96770502
53TIE10.95851244
54MYLK0.93393755
55FER0.93266518
56SGK20.92465049
57PDK40.88534239
58PDK30.88534239
59TBK10.88490340
60EPHB10.87542285
61MAPK150.87241848
62PRKCZ0.87208357
63PRKACA0.86743608
64ERBB20.83648410
65JAK10.83197103
66MAPK40.83019607
67GSK3A0.82045486
68NUAK10.82013079
69MAP3K40.81346330
70PRKCE0.78338793
71DYRK1B0.71384649
72PRKAA10.71235652
73MET0.70971475
74PRKACG0.67618182
75TGFBR20.67073977
76MAPK120.67056764
77KIT0.65039703
78MAP2K60.63188904
79MAP3K110.63063066
80ADRBK20.62128376
81ERBB30.61526759
82NLK0.60855424
83CSK0.59721795
84NEK10.58445869
85CAMK2G0.57584168
86MAP3K100.57014360
87CDK60.56628929
88EPHA30.56114079
89BRSK20.55897721
90PRKACB0.55531382
91MAPKAPK30.55393148
92PTK20.53227363
93FGFR30.52576083
94DYRK1A0.52425225
95STK380.51371053
96CSNK1A10.51091064
97BLK0.50615312
98YES10.49822191
99PDPK10.49477800
100ADRBK10.49452385
101PDK20.49417637
102IKBKE0.48776624
103CSNK1G20.48186191
104SGK10.47569556
105RIPK10.47174884
106EIF2AK30.45889895
107PRKCB0.45529821
108MAPK70.43631899
109PRKCQ0.43335408
110RPS6KA30.43021776
111EIF2AK10.42997455
112MAP2K70.42910539
113MAP3K20.42585129
114CAMK10.42516909
115MUSK0.42237380
116EPHB20.40954656
117GRK10.40667229
118TAOK20.39086073
119IRAK10.38776934
120CCNB10.38578540
121IRAK20.38553472
122MAP3K50.37939987
123IGF1R0.37828889
124CSNK1G10.37099020
125CSF1R0.36353013
126STK160.35891912
127RAF10.35794630
128MAPK130.35556077
129CAMK1D0.35305321
130CSNK1D0.34526922
131CSNK1G30.34267249
132PRKCG0.33881697
133DYRK20.33757733
134MAP3K60.31616981
135PKN10.28524647
136PDK10.27677772
137PBK0.27267523
138PRKCA0.26156022
139CAMK40.25761538
140MAP2K10.25421771
141EGFR0.23816270
142CDK40.23156763
143EPHA40.22287188
144ABL10.19817866
145PRKCD0.19464781
146MTOR0.19085195
147MAP3K130.18671207
148PAK30.16468103

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.29159219
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.49217151
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.28130697
4Nitrogen metabolism_Homo sapiens_hsa009103.24470591
5Arginine biosynthesis_Homo sapiens_hsa002202.87290530
6Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.79156515
7Tryptophan metabolism_Homo sapiens_hsa003802.75490883
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.59256256
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.55758136
10Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.55338780
11Fatty acid degradation_Homo sapiens_hsa000712.54853539
12Pentose and glucuronate interconversions_Homo sapiens_hsa000402.47826222
13Complement and coagulation cascades_Homo sapiens_hsa046102.45591431
14Butanoate metabolism_Homo sapiens_hsa006502.45119119
15Peroxisome_Homo sapiens_hsa041462.25895719
16Propanoate metabolism_Homo sapiens_hsa006402.16952584
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.08583443
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.88741025
19Steroid hormone biosynthesis_Homo sapiens_hsa001401.88430278
20Histidine metabolism_Homo sapiens_hsa003401.86015146
21Chemical carcinogenesis_Homo sapiens_hsa052041.85646909
22Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.83794220
23beta-Alanine metabolism_Homo sapiens_hsa004101.83090307
24Fatty acid metabolism_Homo sapiens_hsa012121.82556250
25PPAR signaling pathway_Homo sapiens_hsa033201.80750674
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.70851291
27Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.68772481
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.68499175
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.68232813
30Retinol metabolism_Homo sapiens_hsa008301.63433759
31Selenocompound metabolism_Homo sapiens_hsa004501.58482463
32Caffeine metabolism_Homo sapiens_hsa002321.55685927
33Pyruvate metabolism_Homo sapiens_hsa006201.54539633
34Bile secretion_Homo sapiens_hsa049761.52834706
35Staphylococcus aureus infection_Homo sapiens_hsa051501.52418106
36Sulfur metabolism_Homo sapiens_hsa009201.45212053
37Cyanoamino acid metabolism_Homo sapiens_hsa004601.38296347
38Tyrosine metabolism_Homo sapiens_hsa003501.35090138
39Starch and sucrose metabolism_Homo sapiens_hsa005001.33082995
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.32607045
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.28754765
42Fatty acid elongation_Homo sapiens_hsa000621.26375816
43Folate biosynthesis_Homo sapiens_hsa007901.23565586
44Carbon metabolism_Homo sapiens_hsa012001.22941336
45Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.22672726
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.19416415
47Biosynthesis of amino acids_Homo sapiens_hsa012301.18863539
48* Phenylalanine metabolism_Homo sapiens_hsa003601.18620473
49Steroid biosynthesis_Homo sapiens_hsa001001.12673502
50ABC transporters_Homo sapiens_hsa020101.09296438
51Arginine and proline metabolism_Homo sapiens_hsa003301.05838496
52Vitamin digestion and absorption_Homo sapiens_hsa049771.04642547
53Maturity onset diabetes of the young_Homo sapiens_hsa049500.98852534
54Fat digestion and absorption_Homo sapiens_hsa049750.93805098
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92204561
56Lysine degradation_Homo sapiens_hsa003100.90176772
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88729055
58Sulfur relay system_Homo sapiens_hsa041220.86459354
59Vitamin B6 metabolism_Homo sapiens_hsa007500.85706999
60Glutathione metabolism_Homo sapiens_hsa004800.85436055
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77819555
62Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76084543
63One carbon pool by folate_Homo sapiens_hsa006700.71319005
64Glycerolipid metabolism_Homo sapiens_hsa005610.70717612
65Pentose phosphate pathway_Homo sapiens_hsa000300.60277502
66Metabolic pathways_Homo sapiens_hsa011000.50262781
67Fatty acid biosynthesis_Homo sapiens_hsa000610.35996171
68Fructose and mannose metabolism_Homo sapiens_hsa000510.33827529
69Prion diseases_Homo sapiens_hsa050200.28645805
70Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.26090944
71Galactose metabolism_Homo sapiens_hsa000520.24197498
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.21426438
73Pertussis_Homo sapiens_hsa051330.19503510
74Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19447236
75Insulin resistance_Homo sapiens_hsa049310.18718375
76Adipocytokine signaling pathway_Homo sapiens_hsa049200.17926989
77Linoleic acid metabolism_Homo sapiens_hsa005910.12479990
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.07904352
79Serotonergic synapse_Homo sapiens_hsa047260.05306705
80Glucagon signaling pathway_Homo sapiens_hsa049220.04714864
81Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.01614786
82Sphingolipid metabolism_Homo sapiens_hsa00600-0.2419005
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2321246
84African trypanosomiasis_Homo sapiens_hsa05143-0.2268104
85Type II diabetes mellitus_Homo sapiens_hsa04930-0.2244057
86Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.2119581
87Ether lipid metabolism_Homo sapiens_hsa00565-0.2103842
88Systemic lupus erythematosus_Homo sapiens_hsa05322-0.2097951
89Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563-0.2000975
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1906208
91Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1687444
92Lysosome_Homo sapiens_hsa04142-0.1642922
93Hepatitis C_Homo sapiens_hsa05160-0.1623540
94Insulin signaling pathway_Homo sapiens_hsa04910-0.1594254
95Vascular smooth muscle contraction_Homo sapiens_hsa04270-0.1584012
96Circadian rhythm_Homo sapiens_hsa04710-0.1581514
97Amoebiasis_Homo sapiens_hsa05146-0.1392432
98Other glycan degradation_Homo sapiens_hsa00511-0.1377635
99Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1254534
100Protein digestion and absorption_Homo sapiens_hsa04974-0.1185307
101Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1174444
102Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1114762
103Mineral absorption_Homo sapiens_hsa04978-0.0979566
104Regulation of autophagy_Homo sapiens_hsa04140-0.0934416
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0904775
106Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0625886
107Renin-angiotensin system_Homo sapiens_hsa04614-0.0593858
108Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0345778
109AMPK signaling pathway_Homo sapiens_hsa04152-0.0147763
110Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0143299

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »