

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 9.54838120 |
| 2 | thrombin receptor signaling pathway (GO:0070493) | 8.34291087 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 6.70734028 |
| 4 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.99551264 |
| 5 | regulation of integrin-mediated signaling pathway (GO:2001044) | 5.75588395 |
| 6 | blood coagulation, intrinsic pathway (GO:0007597) | 5.66639683 |
| 7 | regulation of platelet aggregation (GO:0090330) | 5.57967910 |
| 8 | regulation of platelet activation (GO:0010543) | 5.50502452 |
| 9 | negative regulation of norepinephrine secretion (GO:0010700) | 5.32833384 |
| 10 | adenosine receptor signaling pathway (GO:0001973) | 5.27474955 |
| 11 | negative regulation of thymocyte apoptotic process (GO:0070244) | 4.92898274 |
| 12 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.88252181 |
| 13 | platelet aggregation (GO:0070527) | 4.79647382 |
| 14 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 4.73941811 |
| 15 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 4.56186464 |
| 16 | low-density lipoprotein particle remodeling (GO:0034374) | 4.55551183 |
| 17 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 4.55292463 |
| 18 | negative regulation of heart rate (GO:0010459) | 4.54428161 |
| 19 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 4.51748865 |
| 20 | negative regulation of platelet activation (GO:0010544) | 4.47829566 |
| 21 | negative regulation of protein localization to cell surface (GO:2000009) | 4.40069358 |
| 22 | regulation of lipoprotein metabolic process (GO:0050746) | 4.34108550 |
| 23 | positive regulation of mast cell activation (GO:0033005) | 4.14226031 |
| 24 | positive regulation of endothelial cell differentiation (GO:0045603) | 4.13244157 |
| 25 | negative regulation of appetite (GO:0032099) | 4.06152453 |
| 26 | negative regulation of response to food (GO:0032096) | 4.06152453 |
| 27 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 4.04430670 |
| 28 | angiogenesis involved in wound healing (GO:0060055) | 4.04361978 |
| 29 | neutrophil activation (GO:0042119) | 4.01061156 |
| 30 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.97553494 |
| 31 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.97553494 |
| 32 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.95043853 |
| 33 | megakaryocyte development (GO:0035855) | 3.94084644 |
| 34 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.90725930 |
| 35 | lipoxygenase pathway (GO:0019372) | 3.88232599 |
| 36 | beta-amyloid metabolic process (GO:0050435) | 3.86901184 |
| 37 | fatty acid elongation (GO:0030497) | 3.86539608 |
| 38 | microtubule depolymerization (GO:0007019) | 3.68212593 |
| 39 | regulation of norepinephrine secretion (GO:0014061) | 3.67506874 |
| 40 | regulation of female receptivity (GO:0045924) | 3.65033445 |
| 41 | purinergic receptor signaling pathway (GO:0035587) | 3.62291442 |
| 42 | high-density lipoprotein particle remodeling (GO:0034375) | 3.58573276 |
| 43 | platelet degranulation (GO:0002576) | 3.51169872 |
| 44 | positive regulation of protein homodimerization activity (GO:0090073) | 3.47401967 |
| 45 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.47293157 |
| 46 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.46797339 |
| 47 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.43894370 |
| 48 | reverse cholesterol transport (GO:0043691) | 3.40124608 |
| 49 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.39265598 |
| 50 | regulation of integrin activation (GO:0033623) | 3.38875357 |
| 51 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.38379610 |
| 52 | polyamine biosynthetic process (GO:0006596) | 3.37313795 |
| 53 | granulocyte activation (GO:0036230) | 3.37253845 |
| 54 | dopamine transport (GO:0015872) | 3.35467528 |
| 55 | adenosine metabolic process (GO:0046085) | 3.35428040 |
| 56 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 3.34840860 |
| 57 | platelet formation (GO:0030220) | 3.28918292 |
| 58 | negative regulation of catecholamine secretion (GO:0033604) | 3.28598696 |
| 59 | monoamine transport (GO:0015844) | 3.28472520 |
| 60 | positive regulation of macrophage differentiation (GO:0045651) | 3.28448905 |
| 61 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.26700119 |
| 62 | autophagic vacuole fusion (GO:0000046) | 3.25889977 |
| 63 | phospholipid homeostasis (GO:0055091) | 3.24043969 |
| 64 | negative regulation of neural precursor cell proliferation (GO:2000178) | 3.22179085 |
| 65 | platelet activation (GO:0030168) | 3.21683923 |
| 66 | homotypic cell-cell adhesion (GO:0034109) | 3.21324355 |
| 67 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 3.20969885 |
| 68 | positive regulation of systemic arterial blood pressure (GO:0003084) | 3.20135388 |
| 69 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.19745870 |
| 70 | regulation of memory T cell differentiation (GO:0043380) | 3.17351210 |
| 71 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 3.16349681 |
| 72 | regulation of glutamate secretion (GO:0014048) | 3.15491510 |
| 73 | positive regulation of granulocyte differentiation (GO:0030854) | 3.12557368 |
| 74 | negative regulation of heart contraction (GO:0045822) | 3.10902357 |
| 75 | positive regulation of hemostasis (GO:1900048) | 3.10399535 |
| 76 | positive regulation of blood coagulation (GO:0030194) | 3.10399535 |
| 77 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 3.04932422 |
| 78 | female mating behavior (GO:0060180) | 3.03810454 |
| 79 | positive regulation of amino acid transport (GO:0051957) | 3.01400577 |
| 80 | sequestering of actin monomers (GO:0042989) | 2.99070168 |
| 81 | regulation of homotypic cell-cell adhesion (GO:0034110) | 2.97681722 |
| 82 | mitochondrial calcium ion homeostasis (GO:0051560) | 2.89190984 |
| 83 | positive regulation of receptor recycling (GO:0001921) | 2.88364696 |
| 84 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.87939575 |
| 85 | positive regulation of coagulation (GO:0050820) | 2.86070897 |
| 86 | termination of signal transduction (GO:0023021) | 2.86042800 |
| 87 | negative regulation of T cell apoptotic process (GO:0070233) | 2.85283046 |
| 88 | cellular biogenic amine biosynthetic process (GO:0042401) | 2.83677582 |
| 89 | mitochondrial calcium ion transport (GO:0006851) | 2.83077157 |
| 90 | regulation of endothelial cell differentiation (GO:0045601) | 2.82954423 |
| 91 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.81608581 |
| 92 | endothelium development (GO:0003158) | 2.79621344 |
| 93 | peptide catabolic process (GO:0043171) | 2.78773161 |
| 94 | regulation of cholesterol efflux (GO:0010874) | 2.77154649 |
| 95 | regulation of mitochondrial depolarization (GO:0051900) | 2.76338758 |
| 96 | regulation of megakaryocyte differentiation (GO:0045652) | 2.76327104 |
| 97 | regulation of hemostasis (GO:1900046) | 2.76139169 |
| 98 | regulation of blood coagulation (GO:0030193) | 2.76139169 |
| 99 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.75744073 |
| 100 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 2.75284209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 3.95226217 |
| 2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.69427855 |
| 3 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 3.64603229 |
| 4 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.38702749 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.99978618 |
| 6 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.92886806 |
| 7 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.63376732 |
| 8 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.56639176 |
| 9 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.55785910 |
| 10 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.54002056 |
| 11 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.42601680 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.34469294 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.19402732 |
| 14 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.17215266 |
| 15 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.16058329 |
| 16 | GATA1_19941826_ChIP-Seq_K562_Human | 2.15929766 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 2.14964326 |
| 18 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.07436412 |
| 19 | HTT_18923047_ChIP-ChIP_STHdh_Human | 2.02797072 |
| 20 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.01680804 |
| 21 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.94202728 |
| 22 | GATA2_19941826_ChIP-Seq_K562_Human | 1.93768074 |
| 23 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.92770938 |
| 24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.92436729 |
| 25 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.82840325 |
| 26 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.76786827 |
| 27 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.75591304 |
| 28 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.73317813 |
| 29 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.69649498 |
| 30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68258477 |
| 31 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.63271991 |
| 32 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.60754786 |
| 33 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.59488677 |
| 34 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.56488727 |
| 35 | AR_25329375_ChIP-Seq_VCAP_Human | 1.53271326 |
| 36 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.49532316 |
| 37 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.49404095 |
| 38 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.47031590 |
| 39 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.46773025 |
| 40 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.44900027 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.44330680 |
| 42 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.42519411 |
| 43 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.40432433 |
| 44 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.40307834 |
| 45 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.38909550 |
| 46 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.38345364 |
| 47 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.37415259 |
| 48 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.37415259 |
| 49 | SPI1_23127762_ChIP-Seq_K562_Human | 1.34382842 |
| 50 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.32338678 |
| 51 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.30445814 |
| 52 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.30014969 |
| 53 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.29883304 |
| 54 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.29729143 |
| 55 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.29282325 |
| 56 | TCF4_23295773_ChIP-Seq_U87_Human | 1.26169789 |
| 57 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.22492966 |
| 58 | GATA1_22025678_ChIP-Seq_K562_Human | 1.19716792 |
| 59 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.18549229 |
| 60 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.18172867 |
| 61 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.17614789 |
| 62 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.17579518 |
| 63 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.17579518 |
| 64 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.17111097 |
| 65 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.16824245 |
| 66 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.15020886 |
| 67 | STAT3_23295773_ChIP-Seq_U87_Human | 1.13259344 |
| 68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.12304690 |
| 69 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.10952157 |
| 70 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.10151674 |
| 71 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.10022378 |
| 72 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.09097578 |
| 73 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.06204785 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 1.05178184 |
| 75 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.04480568 |
| 76 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.04125440 |
| 77 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.03670760 |
| 78 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03272243 |
| 79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.03242434 |
| 80 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.02740478 |
| 81 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.02486435 |
| 82 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02092401 |
| 83 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.02032836 |
| 84 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.01838346 |
| 85 | FUS_26573619_Chip-Seq_HEK293_Human | 1.00175663 |
| 86 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.99587797 |
| 87 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.99331655 |
| 88 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98339881 |
| 89 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.97995543 |
| 90 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.95890894 |
| 91 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95890894 |
| 92 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.95750249 |
| 93 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.94719510 |
| 94 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.94551026 |
| 95 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.94090840 |
| 96 | JUN_21703547_ChIP-Seq_K562_Human | 0.93437301 |
| 97 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.92686114 |
| 98 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.91534092 |
| 99 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.90116851 |
| 100 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.89786773 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005464_abnormal_platelet_physiology | 9.45168054 |
| 2 | MP0008004_abnormal_stomach_pH | 5.24875347 |
| 3 | MP0000465_gastrointestinal_hemorrhage | 4.02334195 |
| 4 | MP0003724_increased_susceptibility_to | 3.38507715 |
| 5 | MP0002736_abnormal_nociception_after | 3.35489566 |
| 6 | MP0005646_abnormal_pituitary_gland | 2.93820204 |
| 7 | MP0009697_abnormal_copulation | 2.65892637 |
| 8 | MP0008872_abnormal_physiological_respon | 2.50940286 |
| 9 | MP0000230_abnormal_systemic_arterial | 2.25522812 |
| 10 | MP0001968_abnormal_touch/_nociception | 2.20316896 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.17310321 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 2.05964159 |
| 13 | MP0005410_abnormal_fertilization | 2.03870474 |
| 14 | MP0004084_abnormal_cardiac_muscle | 2.02827966 |
| 15 | MP0004510_myositis | 2.01935701 |
| 16 | MP0008775_abnormal_heart_ventricle | 2.01671416 |
| 17 | MP0000343_altered_response_to | 1.89795868 |
| 18 | MP0005167_abnormal_blood-brain_barrier | 1.89169892 |
| 19 | MP0005083_abnormal_biliary_tract | 1.88286677 |
| 20 | MP0003638_abnormal_response/metabolism_ | 1.72386947 |
| 21 | MP0009780_abnormal_chondrocyte_physiolo | 1.69774759 |
| 22 | MP0003718_maternal_effect | 1.64415414 |
| 23 | MP0010329_abnormal_lipoprotein_level | 1.40545186 |
| 24 | MP0004215_abnormal_myocardial_fiber | 1.37746454 |
| 25 | MP0010155_abnormal_intestine_physiology | 1.33970670 |
| 26 | MP0001879_abnormal_lymphatic_vessel | 1.33958285 |
| 27 | MP0002733_abnormal_thermal_nociception | 1.32533515 |
| 28 | MP0004036_abnormal_muscle_relaxation | 1.31702159 |
| 29 | MP0001851_eye_inflammation | 1.30913908 |
| 30 | MP0006276_abnormal_autonomic_nervous | 1.29478535 |
| 31 | MP0002735_abnormal_chemical_nociception | 1.29355547 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.29190931 |
| 33 | MP0005671_abnormal_response_to | 1.27352720 |
| 34 | MP0003303_peritoneal_inflammation | 1.25097609 |
| 35 | MP0003787_abnormal_imprinting | 1.25063166 |
| 36 | MP0001545_abnormal_hematopoietic_system | 1.24814709 |
| 37 | MP0005397_hematopoietic_system_phenotyp | 1.24814709 |
| 38 | MP0006054_spinal_hemorrhage | 1.23852006 |
| 39 | MP0002398_abnormal_bone_marrow | 1.23230437 |
| 40 | MP0003828_pulmonary_edema | 1.22387067 |
| 41 | MP0008877_abnormal_DNA_methylation | 1.18953930 |
| 42 | MP0000249_abnormal_blood_vessel | 1.16035473 |
| 43 | MP0009764_decreased_sensitivity_to | 1.08660069 |
| 44 | MP0009763_increased_sensitivity_to | 1.03985489 |
| 45 | MP0005000_abnormal_immune_tolerance | 1.03962785 |
| 46 | MP0001663_abnormal_digestive_system | 1.03365255 |
| 47 | MP0002102_abnormal_ear_morphology | 1.02934355 |
| 48 | MP0004147_increased_porphyrin_level | 1.02912517 |
| 49 | MP0002132_abnormal_respiratory_system | 1.01188568 |
| 50 | MP0003566_abnormal_cell_adhesion | 0.99919963 |
| 51 | MP0001970_abnormal_pain_threshold | 0.98861543 |
| 52 | MP0009765_abnormal_xenobiotic_induced | 0.97968308 |
| 53 | MP0000689_abnormal_spleen_morphology | 0.95849890 |
| 54 | MP0003136_yellow_coat_color | 0.92872716 |
| 55 | MP0005174_abnormal_tail_pigmentation | 0.92457400 |
| 56 | MP0005551_abnormal_eye_electrophysiolog | 0.90385639 |
| 57 | MP0000383_abnormal_hair_follicle | 0.87924076 |
| 58 | MP0003656_abnormal_erythrocyte_physiolo | 0.87880498 |
| 59 | MP0004130_abnormal_muscle_cell | 0.87702950 |
| 60 | MP0005647_abnormal_sex_gland | 0.87087187 |
| 61 | MP0003879_abnormal_hair_cell | 0.86076607 |
| 62 | MP0005499_abnormal_olfactory_system | 0.85525108 |
| 63 | MP0005394_taste/olfaction_phenotype | 0.85525108 |
| 64 | MP0009642_abnormal_blood_homeostasis | 0.82937814 |
| 65 | MP0008874_decreased_physiological_sensi | 0.82044499 |
| 66 | MP0000372_irregular_coat_pigmentation | 0.81621384 |
| 67 | MP0002653_abnormal_ependyma_morphology | 0.79460680 |
| 68 | MP0001765_abnormal_ion_homeostasis | 0.78608831 |
| 69 | MP0002429_abnormal_blood_cell | 0.78078925 |
| 70 | MP0002723_abnormal_immune_serum | 0.74929258 |
| 71 | MP0004484_altered_response_of | 0.74490133 |
| 72 | MP0005187_abnormal_penis_morphology | 0.72367504 |
| 73 | MP0002722_abnormal_immune_system | 0.71627991 |
| 74 | MP0002452_abnormal_antigen_presenting | 0.70365645 |
| 75 | MP0003698_abnormal_male_reproductive | 0.68719880 |
| 76 | MP0006036_abnormal_mitochondrial_physio | 0.67667945 |
| 77 | MP0000015_abnormal_ear_pigmentation | 0.67573288 |
| 78 | MP0004947_skin_inflammation | 0.66425666 |
| 79 | MP0004142_abnormal_muscle_tone | 0.65943261 |
| 80 | MP0002128_abnormal_blood_circulation | 0.65908897 |
| 81 | MP0001800_abnormal_humoral_immune | 0.65550989 |
| 82 | MP0010094_abnormal_chromosome_stability | 0.63715711 |
| 83 | MP0004085_abnormal_heartbeat | 0.62989168 |
| 84 | MP0006138_congestive_heart_failure | 0.62779231 |
| 85 | MP0002972_abnormal_cardiac_muscle | 0.61976442 |
| 86 | MP0000858_altered_metastatic_potential | 0.61275412 |
| 87 | MP0005535_abnormal_body_temperature | 0.61144564 |
| 88 | MP0001664_abnormal_digestion | 0.60143542 |
| 89 | MP0008789_abnormal_olfactory_epithelium | 0.59620656 |
| 90 | MP0000716_abnormal_immune_system | 0.59494821 |
| 91 | MP0008057_abnormal_DNA_replication | 0.59019286 |
| 92 | MP0004381_abnormal_hair_follicle | 0.58055069 |
| 93 | MP0005645_abnormal_hypothalamus_physiol | 0.57421253 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.57276944 |
| 95 | MP0003866_abnormal_defecation | 0.57159566 |
| 96 | MP0005385_cardiovascular_system_phenoty | 0.56791943 |
| 97 | MP0001544_abnormal_cardiovascular_syste | 0.56791943 |
| 98 | MP0003183_abnormal_peptide_metabolism | 0.55091057 |
| 99 | MP0002420_abnormal_adaptive_immunity | 0.54755173 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.54726030 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Menorrhagia (HP:0000132) | 9.75530715 |
| 2 | Increased mean platelet volume (HP:0011877) | 9.70080958 |
| 3 | Petechiae (HP:0000967) | 9.07654881 |
| 4 | Abnormal platelet volume (HP:0011876) | 9.02077403 |
| 5 | Purpura (HP:0000979) | 7.86686362 |
| 6 | Epistaxis (HP:0000421) | 7.14042041 |
| 7 | Gingival bleeding (HP:0000225) | 6.44383504 |
| 8 | Hyperlipoproteinemia (HP:0010980) | 5.93831998 |
| 9 | Dyschromatopsia (HP:0007641) | 5.16201307 |
| 10 | Impaired platelet aggregation (HP:0003540) | 5.12645528 |
| 11 | Abnormal platelet function (HP:0011869) | 5.12645528 |
| 12 | Poikilocytosis (HP:0004447) | 4.24220048 |
| 13 | Acanthocytosis (HP:0001927) | 4.13756028 |
| 14 | Abnormal pupillary function (HP:0007686) | 3.81785046 |
| 15 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.61721898 |
| 16 | Spontaneous hematomas (HP:0007420) | 3.60417908 |
| 17 | Abnormality of lateral ventricle (HP:0030047) | 3.37763383 |
| 18 | Bruising susceptibility (HP:0000978) | 3.19413455 |
| 19 | Decreased central vision (HP:0007663) | 2.99642532 |
| 20 | Conjunctival telangiectasia (HP:0000524) | 2.97715326 |
| 21 | Abnormality of the common coagulation pathway (HP:0010990) | 2.95671848 |
| 22 | Upper limb muscle weakness (HP:0003484) | 2.74780412 |
| 23 | Paralysis (HP:0003470) | 2.73456891 |
| 24 | Spontaneous abortion (HP:0005268) | 2.69565606 |
| 25 | Abnormal auditory evoked potentials (HP:0006958) | 2.68183520 |
| 26 | Papillary thyroid carcinoma (HP:0002895) | 2.67805786 |
| 27 | Increased density of long bones (HP:0006392) | 2.65151981 |
| 28 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.54248729 |
| 29 | Joint hemorrhage (HP:0005261) | 2.50708415 |
| 30 | Stomatitis (HP:0010280) | 2.31972234 |
| 31 | Thyroid-stimulating hormone excess (HP:0002925) | 2.27235670 |
| 32 | Abnormality of the prostate (HP:0008775) | 2.23828333 |
| 33 | Xanthomatosis (HP:0000991) | 2.22624836 |
| 34 | Tinnitus (HP:0000360) | 2.17043239 |
| 35 | Increased IgM level (HP:0003496) | 2.16663590 |
| 36 | Autoimmune hemolytic anemia (HP:0001890) | 2.12940255 |
| 37 | Hepatosplenomegaly (HP:0001433) | 2.11534685 |
| 38 | Biliary tract neoplasm (HP:0100574) | 2.06572396 |
| 39 | Abnormal spermatogenesis (HP:0008669) | 2.06228313 |
| 40 | Prolonged bleeding time (HP:0003010) | 10.8169387 |
| 41 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 1.99969971 |
| 42 | Delusions (HP:0000746) | 1.96781706 |
| 43 | Nausea (HP:0002018) | 1.96155083 |
| 44 | Tongue fasciculations (HP:0001308) | 1.95939176 |
| 45 | Joint swelling (HP:0001386) | 1.94847414 |
| 46 | Abnormal ciliary motility (HP:0012262) | 1.92274625 |
| 47 | Polyphagia (HP:0002591) | 1.92068719 |
| 48 | 3-Methylglutaconic aciduria (HP:0003535) | 1.90235770 |
| 49 | Encephalitis (HP:0002383) | 1.87799825 |
| 50 | Generalized aminoaciduria (HP:0002909) | 1.87786258 |
| 51 | Thyroid carcinoma (HP:0002890) | 1.83059811 |
| 52 | Arterial thrombosis (HP:0004420) | 1.82669902 |
| 53 | Abnormality of iron homeostasis (HP:0011031) | 1.75793000 |
| 54 | Panhypogammaglobulinemia (HP:0003139) | 1.75560002 |
| 55 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.75298890 |
| 56 | Febrile seizures (HP:0002373) | 1.73915418 |
| 57 | Abolished electroretinogram (ERG) (HP:0000550) | 1.73459800 |
| 58 | Male infertility (HP:0003251) | 1.71357516 |
| 59 | Renal cortical cysts (HP:0000803) | 1.70188965 |
| 60 | Hyperventilation (HP:0002883) | 1.69491338 |
| 61 | Muscle fibrillation (HP:0010546) | 1.64348320 |
| 62 | Abnormality of the renal cortex (HP:0011035) | 1.59644344 |
| 63 | Acute hepatic failure (HP:0006554) | 1.55151447 |
| 64 | Widely spaced teeth (HP:0000687) | 1.54787285 |
| 65 | Amaurosis fugax (HP:0100576) | 1.52212567 |
| 66 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.51973653 |
| 67 | Absent speech (HP:0001344) | 1.50698499 |
| 68 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.50456252 |
| 69 | Absent/shortened dynein arms (HP:0200106) | 1.50456252 |
| 70 | Tented upper lip vermilion (HP:0010804) | 1.50386475 |
| 71 | Hypophosphatemic rickets (HP:0004912) | 1.48820920 |
| 72 | Infertility (HP:0000789) | 1.48756912 |
| 73 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.46211229 |
| 74 | Abnormality of alanine metabolism (HP:0010916) | 1.46211229 |
| 75 | Hyperalaninemia (HP:0003348) | 1.46211229 |
| 76 | Central scotoma (HP:0000603) | 1.45817295 |
| 77 | Ectopic kidney (HP:0000086) | 1.45559708 |
| 78 | Myelodysplasia (HP:0002863) | 1.43223938 |
| 79 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.41597429 |
| 80 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.41597429 |
| 81 | Delayed puberty (HP:0000823) | 1.41589134 |
| 82 | Leiomyosarcoma (HP:0100243) | 1.41399192 |
| 83 | Uterine leiomyosarcoma (HP:0002891) | 1.41399192 |
| 84 | Bladder carcinoma (HP:0002862) | 1.37361238 |
| 85 | Bladder neoplasm (HP:0009725) | 1.37361238 |
| 86 | Male pseudohermaphroditism (HP:0000037) | 1.37194042 |
| 87 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.34946206 |
| 88 | Eosinophilia (HP:0001880) | 1.34039957 |
| 89 | Abnormality of male internal genitalia (HP:0000022) | 1.33289839 |
| 90 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.32774221 |
| 91 | Pancreatic cysts (HP:0001737) | 1.32654475 |
| 92 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.32121565 |
| 93 | Azoospermia (HP:0000027) | 1.31970069 |
| 94 | Vertigo (HP:0002321) | 1.31588803 |
| 95 | Abnormality of B cell number (HP:0010975) | 1.31515347 |
| 96 | Episodic fever (HP:0001954) | 1.30694441 |
| 97 | Amyotrophic lateral sclerosis (HP:0007354) | 1.30488590 |
| 98 | Gonadal dysgenesis (HP:0000133) | 1.27072529 |
| 99 | Chest pain (HP:0100749) | 1.26877658 |
| 100 | Hypoproteinemia (HP:0003075) | 1.26696165 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 5.64170856 |
| 2 | EIF2AK1 | 3.46911405 |
| 3 | BMX | 3.42861319 |
| 4 | RIPK4 | 3.19413284 |
| 5 | TEC | 2.88104896 |
| 6 | MYLK | 2.87532737 |
| 7 | BTK | 2.59574014 |
| 8 | NUAK1 | 2.47540785 |
| 9 | TAOK3 | 2.24998810 |
| 10 | PTK2B | 2.15401549 |
| 11 | EIF2AK3 | 2.10400374 |
| 12 | ACVR1B | 1.92155962 |
| 13 | GRK5 | 1.89654342 |
| 14 | TRIM28 | 1.86997841 |
| 15 | PLK2 | 1.82755007 |
| 16 | CSF1R | 1.80917853 |
| 17 | PIK3CG | 1.80108692 |
| 18 | SYK | 1.80073910 |
| 19 | TNK2 | 1.77116273 |
| 20 | BMPR2 | 1.69479294 |
| 21 | ADRBK2 | 1.67405316 |
| 22 | MAPK13 | 1.64915433 |
| 23 | MAP4K2 | 1.64905779 |
| 24 | STK39 | 1.63054173 |
| 25 | FRK | 1.61762433 |
| 26 | STK3 | 1.58729504 |
| 27 | BMPR1B | 1.56909390 |
| 28 | IRAK1 | 1.54274835 |
| 29 | FER | 1.41089907 |
| 30 | ILK | 1.28270596 |
| 31 | ZAK | 1.27258757 |
| 32 | GRK6 | 1.25043196 |
| 33 | PNCK | 1.16069826 |
| 34 | FGR | 1.12328147 |
| 35 | IRAK2 | 1.12094772 |
| 36 | MAPKAPK3 | 1.01442707 |
| 37 | OXSR1 | 0.98372765 |
| 38 | WNK3 | 0.97329986 |
| 39 | LYN | 0.96559093 |
| 40 | HCK | 0.94641813 |
| 41 | PKN1 | 0.93511730 |
| 42 | PAK1 | 0.91135491 |
| 43 | EPHA3 | 0.90241087 |
| 44 | PAK3 | 0.89637928 |
| 45 | PIM2 | 0.87977204 |
| 46 | TNIK | 0.85948325 |
| 47 | MAP3K5 | 0.85885862 |
| 48 | FES | 0.83520185 |
| 49 | ADRBK1 | 0.83159680 |
| 50 | MINK1 | 0.81612818 |
| 51 | DYRK2 | 0.81608012 |
| 52 | INSRR | 0.78217080 |
| 53 | MATK | 0.75229014 |
| 54 | BRSK2 | 0.74748314 |
| 55 | PLK3 | 0.70030113 |
| 56 | ITK | 0.69541048 |
| 57 | IKBKB | 0.69441333 |
| 58 | DAPK3 | 0.69128696 |
| 59 | SGK2 | 0.69103095 |
| 60 | VRK1 | 0.66328701 |
| 61 | CDC7 | 0.64783937 |
| 62 | SIK3 | 0.62323564 |
| 63 | ZAP70 | 0.59949488 |
| 64 | LMTK2 | 0.59781881 |
| 65 | MAP3K12 | 0.58889425 |
| 66 | TLK1 | 0.58333821 |
| 67 | CAMK1G | 0.56245592 |
| 68 | MARK3 | 0.55959248 |
| 69 | PRKCE | 0.54397960 |
| 70 | YES1 | 0.54282802 |
| 71 | PRKD1 | 0.54207110 |
| 72 | EPHB2 | 0.54055291 |
| 73 | GRK1 | 0.53369501 |
| 74 | ERBB2 | 0.50705128 |
| 75 | MAP2K1 | 0.49712300 |
| 76 | TXK | 0.48004738 |
| 77 | DAPK2 | 0.47671780 |
| 78 | PRKG1 | 0.45914849 |
| 79 | BLK | 0.44755200 |
| 80 | BCR | 0.44193001 |
| 81 | AKT3 | 0.44180252 |
| 82 | ERBB3 | 0.43602995 |
| 83 | PRKACG | 0.40507909 |
| 84 | IGF1R | 0.40077465 |
| 85 | DYRK1A | 0.36698481 |
| 86 | ROCK1 | 0.36565660 |
| 87 | PDK1 | 0.35605941 |
| 88 | PRKCB | 0.33429832 |
| 89 | DAPK1 | 0.30726791 |
| 90 | STK4 | 0.30639260 |
| 91 | PRKCQ | 0.30634704 |
| 92 | PRKCA | 0.30547156 |
| 93 | LCK | 0.27980512 |
| 94 | CAMK2A | 0.27711955 |
| 95 | ABL1 | 0.27134715 |
| 96 | SGK3 | 0.27078503 |
| 97 | CSNK1D | 0.26788551 |
| 98 | MKNK1 | 0.25323435 |
| 99 | PRKCG | 0.23126774 |
| 100 | GSK3A | 0.21261529 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Platelet activation_Homo sapiens_hsa04611 | 5.64994455 |
| 2 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 3.68170025 |
| 3 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 3.21116718 |
| 4 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.78571696 |
| 5 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 2.49217439 |
| 6 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.39896946 |
| 7 | Mismatch repair_Homo sapiens_hsa03430 | 2.30603996 |
| 8 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.21555793 |
| 9 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.08458145 |
| 10 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.96218507 |
| 11 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.95319317 |
| 12 | Gap junction_Homo sapiens_hsa04540 | 1.79752482 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.75528748 |
| 14 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.72218744 |
| 15 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.60507942 |
| 16 | Alcoholism_Homo sapiens_hsa05034 | 1.58547071 |
| 17 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.55384639 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.52507030 |
| 19 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.49876288 |
| 20 | Olfactory transduction_Homo sapiens_hsa04740 | 1.45719121 |
| 21 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.40644575 |
| 22 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.39335461 |
| 23 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.32879899 |
| 24 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.27563794 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.25087173 |
| 26 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.22199999 |
| 27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.22102201 |
| 28 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.20518311 |
| 29 | Circadian entrainment_Homo sapiens_hsa04713 | 1.18966232 |
| 30 | Long-term depression_Homo sapiens_hsa04730 | 1.16695323 |
| 31 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.13804822 |
| 32 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.13649108 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.08182253 |
| 34 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.05474987 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.04835482 |
| 36 | Morphine addiction_Homo sapiens_hsa05032 | 1.03265016 |
| 37 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.03195345 |
| 38 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.97240182 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.94431005 |
| 40 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.94178914 |
| 41 | Endocytosis_Homo sapiens_hsa04144 | 0.92211564 |
| 42 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.89874730 |
| 43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.85113756 |
| 44 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.83402001 |
| 45 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.82493462 |
| 46 | GABAergic synapse_Homo sapiens_hsa04727 | 0.82215924 |
| 47 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.80922912 |
| 48 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.76699284 |
| 49 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.72951510 |
| 50 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.71257799 |
| 51 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.70181307 |
| 52 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.68366349 |
| 53 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.65230215 |
| 54 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.62412317 |
| 55 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.61480967 |
| 56 | Asthma_Homo sapiens_hsa05310 | 0.59962776 |
| 57 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.59442515 |
| 58 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.59394949 |
| 59 | Purine metabolism_Homo sapiens_hsa00230 | 0.59149940 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.56700307 |
| 61 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.55919089 |
| 62 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.55914127 |
| 63 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.55786485 |
| 64 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.53869268 |
| 65 | Phagosome_Homo sapiens_hsa04145 | 0.51202358 |
| 66 | Base excision repair_Homo sapiens_hsa03410 | 0.50024240 |
| 67 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.49379586 |
| 68 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.49311004 |
| 69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.48438734 |
| 70 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.48195874 |
| 71 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.48183758 |
| 72 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47958759 |
| 73 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.47948263 |
| 74 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.47774719 |
| 75 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.47456988 |
| 76 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.47366592 |
| 77 | Renin secretion_Homo sapiens_hsa04924 | 0.46466477 |
| 78 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.45300223 |
| 79 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.44048672 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.41622655 |
| 81 | Salivary secretion_Homo sapiens_hsa04970 | 0.41091190 |
| 82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.40209390 |
| 83 | Shigellosis_Homo sapiens_hsa05131 | 0.38423504 |
| 84 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37791145 |
| 85 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36447771 |
| 86 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.36229419 |
| 87 | Melanoma_Homo sapiens_hsa05218 | 0.35305733 |
| 88 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.35038102 |
| 89 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.34639298 |
| 90 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.34162171 |
| 91 | Peroxisome_Homo sapiens_hsa04146 | 0.33908107 |
| 92 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.32527379 |
| 93 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.32016632 |
| 94 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.31962882 |
| 95 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.30749556 |
| 96 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.28464471 |
| 97 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.28274271 |
| 98 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.27873974 |
| 99 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.25552413 |
| 100 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.25271351 |

