GLYATL1P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleotide catabolic process (GO:0006244)7.04708859
2B cell receptor signaling pathway (GO:0050853)6.38369174
3nucleoside diphosphate catabolic process (GO:0009134)5.96955690
4pyrimidine ribonucleoside catabolic process (GO:0046133)4.96083160
5regulation of B cell receptor signaling pathway (GO:0050855)4.69617422
6B cell proliferation (GO:0042100)4.38748881
7positive regulation of gamma-delta T cell activation (GO:0046645)4.37676432
8cellular response to interferon-beta (GO:0035458)4.36348747
9CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)4.23515236
10positive regulation of B cell differentiation (GO:0045579)4.09458154
11negative regulation of DNA repair (GO:0045738)4.01924114
12spermatid nucleus differentiation (GO:0007289)3.93704507
13regulation of B cell differentiation (GO:0045577)3.72142029
14T cell lineage commitment (GO:0002360)3.66341787
15regulation of histone H3-K9 methylation (GO:0051570)3.52323591
16regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.47153174
17protein localization to kinetochore (GO:0034501)3.41731081
18positive regulation of protein oligomerization (GO:0032461)3.41541837
19negative regulation of histone methylation (GO:0031061)3.38293382
20histone H4-K12 acetylation (GO:0043983)3.36966662
21ganglion development (GO:0061548)3.36629687
22chromatin remodeling at centromere (GO:0031055)3.36253909
23CENP-A containing nucleosome assembly (GO:0034080)3.32032883
24positive thymic T cell selection (GO:0045059)3.17655955
25V(D)J recombination (GO:0033151)3.14808563
26somatic recombination of immunoglobulin gene segments (GO:0016447)3.12803121
27negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.09157744
28positive regulation of B cell proliferation (GO:0030890)3.08177410
29DNA strand elongation involved in DNA replication (GO:0006271)3.08124263
30somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.01107881
31somatic cell DNA recombination (GO:0016444)3.01107881
32DNA replication-independent nucleosome organization (GO:0034724)3.01075717
33DNA replication-independent nucleosome assembly (GO:0006336)3.01075717
34histone-serine phosphorylation (GO:0035404)2.99960096
35regulation of mitotic spindle checkpoint (GO:1903504)2.99449615
36regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.99449615
37DNA strand elongation (GO:0022616)2.99432041
38regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.98739396
39regulation of gamma-delta T cell activation (GO:0046643)2.98666946
40somatic diversification of immune receptors via somatic mutation (GO:0002566)2.96822693
41somatic hypermutation of immunoglobulin genes (GO:0016446)2.96822693
42regulation of interferon-beta biosynthetic process (GO:0045357)2.96535074
43regulation of B cell proliferation (GO:0030888)2.92736009
44endothelial tube morphogenesis (GO:0061154)2.92176617
45morphogenesis of an endothelium (GO:0003159)2.92176617
46transcription from mitochondrial promoter (GO:0006390)2.90485824
47positive regulation of defense response to virus by host (GO:0002230)2.90385816
48somatic diversification of immunoglobulins (GO:0016445)2.88403324
49histone H3 acetylation (GO:0043966)2.87851305
50mismatch repair (GO:0006298)2.87641696
51regulation of gamma-delta T cell differentiation (GO:0045586)2.87207065
52protein localization to chromosome, centromeric region (GO:0071459)2.87190569
53regulation of chromatin binding (GO:0035561)2.86203586
54telomere maintenance via recombination (GO:0000722)2.85489589
55telomere maintenance via semi-conservative replication (GO:0032201)2.84966022
56somatic diversification of immune receptors (GO:0002200)2.84460409
57negative regulation of DNA recombination (GO:0045910)2.81459002
58regulation of histone methylation (GO:0031060)2.79353890
59histone H4-K8 acetylation (GO:0043982)2.77422503
60histone H4-K5 acetylation (GO:0043981)2.77422503
61positive regulation of B cell activation (GO:0050871)2.76188801
62folic acid-containing compound biosynthetic process (GO:0009396)2.75910774
63DNA topological change (GO:0006265)2.72862234
64response to interferon-beta (GO:0035456)2.71568141
65positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.71352802
66defense response to protozoan (GO:0042832)2.71072375
67positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.70575802
68mitochondrial RNA metabolic process (GO:0000959)2.69173296
69rRNA methylation (GO:0031167)2.67848210
70mucosal-associated lymphoid tissue development (GO:0048537)2.67635390
71Peyers patch development (GO:0048541)2.67635390
72B cell homeostasis (GO:0001782)2.66738692
73mitotic sister chromatid cohesion (GO:0007064)2.65967643
74positive regulation by host of viral transcription (GO:0043923)2.65712253
75dopaminergic neuron differentiation (GO:0071542)2.64594767
76regulation of defense response to virus by host (GO:0050691)2.63495594
77B cell activation (GO:0042113)2.62685275
78viral transcription (GO:0019083)2.61438604
79histone H4-K16 acetylation (GO:0043984)2.60550558
80microtubule depolymerization (GO:0007019)2.58915255
81immunoglobulin mediated immune response (GO:0016064)2.57551212
82antigen receptor-mediated signaling pathway (GO:0050851)2.55865127
83GMP metabolic process (GO:0046037)2.55800158
84positive regulation of histone H3-K4 methylation (GO:0051571)2.55206559
85acrosome assembly (GO:0001675)2.54285968
86mitotic recombination (GO:0006312)2.53087102
87translational termination (GO:0006415)2.52381625
88ATP-dependent chromatin remodeling (GO:0043044)2.52200000
89positive T cell selection (GO:0043368)2.52185389
90pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.49774992
91establishment of chromosome localization (GO:0051303)2.49741572
92mitotic metaphase plate congression (GO:0007080)2.49416606
93negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.48446024
94rRNA modification (GO:0000154)2.48410283
95DNA replication-dependent nucleosome organization (GO:0034723)2.47250781
96DNA replication-dependent nucleosome assembly (GO:0006335)2.47250781
97primitive streak formation (GO:0090009)2.45745296
98production of molecular mediator involved in inflammatory response (GO:0002532)2.44790357
99response to protozoan (GO:0001562)2.44635229
100purine nucleobase biosynthetic process (GO:0009113)2.43849045

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.38715189
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.12089011
3MYC_22102868_ChIP-Seq_BL_Human4.57668894
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.31300737
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.42798815
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.33474919
7MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.18055077
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.98397999
9SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.81857697
10EZH2_22144423_ChIP-Seq_EOC_Human2.79110989
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.76295511
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.54915783
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.53626310
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.50913814
15CIITA_25753668_ChIP-Seq_RAJI_Human2.49207172
16E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.43901863
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.42154471
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.28341503
19IGF1R_20145208_ChIP-Seq_DFB_Human2.23116959
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.16926493
21E2F1_21310950_ChIP-Seq_MCF-7_Human2.16519546
22VDR_23849224_ChIP-Seq_CD4+_Human2.12443254
23GABP_17652178_ChIP-ChIP_JURKAT_Human2.11925676
24MYC_18555785_ChIP-Seq_MESCs_Mouse2.09353456
25IRF8_21731497_ChIP-ChIP_J774_Mouse2.09100895
26GATA1_22025678_ChIP-Seq_K562_Human2.04883358
27CREB1_15753290_ChIP-ChIP_HEK293T_Human2.03232132
28ELK1_19687146_ChIP-ChIP_HELA_Human2.02471754
29MYB_26560356_Chip-Seq_TH2_Human1.93164455
30AR_21909140_ChIP-Seq_LNCAP_Human1.87016654
31MYB_26560356_Chip-Seq_TH1_Human1.83224954
32FOXP3_21729870_ChIP-Seq_TREG_Human1.81763489
33HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.80739062
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.80340488
35STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.80320882
36NOTCH1_21737748_ChIP-Seq_TLL_Human1.73723674
37MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.72710523
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68755343
39SPI1_23547873_ChIP-Seq_NB4_Human1.64924446
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.63116786
41FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.61637321
42MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.58111630
43ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.53908923
44ETS1_20019798_ChIP-Seq_JURKAT_Human1.50590067
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.49484476
46FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.47851284
47KDM5A_27292631_Chip-Seq_BREAST_Human1.47806180
48MYC_19030024_ChIP-ChIP_MESCs_Mouse1.45865986
49CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.44323772
50IRF1_19129219_ChIP-ChIP_H3396_Human1.39546269
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38317292
52ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.37369270
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.36454809
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.36348469
55KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.33415081
56RUNX_20019798_ChIP-Seq_JUKART_Human1.30663873
57MYC_18358816_ChIP-ChIP_MESCs_Mouse1.30437151
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.29681949
59ERG_20887958_ChIP-Seq_HPC-7_Mouse1.27961250
60CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.25975291
61TP63_19390658_ChIP-ChIP_HaCaT_Human1.24940588
62SCL_19346495_ChIP-Seq_HPC-7_Human1.22996815
63UTX_26944678_Chip-Seq_JUKART_Human1.22485557
64MYCN_18555785_ChIP-Seq_MESCs_Mouse1.20459432
65IRF8_27001747_Chip-Seq_BMDM_Mouse1.19003992
66E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.17863289
67NELFA_20434984_ChIP-Seq_ESCs_Mouse1.16736677
68MYC_19079543_ChIP-ChIP_MESCs_Mouse1.13029509
69MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.12072220
70EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.11987060
71VDR_21846776_ChIP-Seq_THP-1_Human1.11408664
72YY1_21170310_ChIP-Seq_MESCs_Mouse1.05084884
73MAF_26560356_Chip-Seq_TH1_Human1.05037666
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03839987
75SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.03610462
76FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03078516
77XRN2_22483619_ChIP-Seq_HELA_Human1.02767165
78AR_21572438_ChIP-Seq_LNCaP_Human1.02483118
79MYB_21317192_ChIP-Seq_ERMYB_Mouse1.00923513
80GATA3_27048872_Chip-Seq_THYMUS_Human1.00241466
81THAP11_20581084_ChIP-Seq_MESCs_Mouse0.97587744
82SOX2_18555785_ChIP-Seq_MESCs_Mouse0.95255970
83PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94367984
84GATA3_26560356_Chip-Seq_TH2_Human0.94086837
85JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.93707186
86SMRT_27268052_Chip-Seq_Bcells_Human0.91827468
87ELF5_23300383_ChIP-Seq_T47D_Human0.89805574
88HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.87377124
89STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.85917784
90VDR_24763502_ChIP-Seq_THP-1_Human0.84717017
91GABP_19822575_ChIP-Seq_HepG2_Human0.83870430
92GATA3_26560356_Chip-Seq_TH1_Human0.82174762
93POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.82172830
94MYC_18940864_ChIP-ChIP_HL60_Human0.81810436
95POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.81641164
96TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81641164
97STAT4_19710469_ChIP-ChIP_TH1__Mouse0.81254127
98RBPJ_22232070_ChIP-Seq_NCS_Mouse0.79644640
99NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.78460983
100ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.74178999

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.36982468
2MP0002009_preneoplasia3.94043166
3MP0003303_peritoneal_inflammation3.79131090
4MP0010094_abnormal_chromosome_stability3.62709419
5MP0002138_abnormal_hepatobiliary_system3.15192496
6MP0001800_abnormal_humoral_immune3.04415233
7MP0001835_abnormal_antigen_presentation2.94674026
8MP0005387_immune_system_phenotype2.93788146
9MP0001790_abnormal_immune_system2.93788146
10MP0002638_abnormal_pupillary_reflex2.92667138
11MP0003763_abnormal_thymus_physiology2.83668824
12MP0000569_abnormal_digit_pigmentation2.77113974
13MP0005310_abnormal_salivary_gland2.58530172
14MP0002166_altered_tumor_susceptibility2.45364166
15MP0008058_abnormal_DNA_repair2.41631784
16MP0002452_abnormal_antigen_presenting2.29003574
17MP0000685_abnormal_immune_system2.27812011
18MP0003077_abnormal_cell_cycle2.25932662
19MP0002398_abnormal_bone_marrow2.15823071
20MP0008007_abnormal_cellular_replicative2.13503470
21MP0003693_abnormal_embryo_hatching2.08846416
22MP0002723_abnormal_immune_serum2.07515042
23MP0002420_abnormal_adaptive_immunity2.02029042
24MP0005000_abnormal_immune_tolerance2.01917040
25MP0002006_tumorigenesis1.96893855
26MP0001819_abnormal_immune_cell1.96422104
27MP0000716_abnormal_immune_system1.83970221
28MP0004957_abnormal_blastocyst_morpholog1.80677399
29MP0000689_abnormal_spleen_morphology1.79366091
30MP0003111_abnormal_nucleus_morphology1.76333946
31MP0008995_early_reproductive_senescence1.74477079
32MP0005671_abnormal_response_to1.66677535
33MP0008877_abnormal_DNA_methylation1.65108265
34MP0005075_abnormal_melanosome_morpholog1.60895066
35MP0002429_abnormal_blood_cell1.49420040
36MP0002722_abnormal_immune_system1.47094856
37MP0001853_heart_inflammation1.43301277
38MP0002139_abnormal_hepatobiliary_system1.40674510
39MP0002653_abnormal_ependyma_morphology1.39012584
40MP0000703_abnormal_thymus_morphology1.36449619
41MP0002405_respiratory_system_inflammati1.35841694
42MP0005025_abnormal_response_to1.35397816
43MP0004808_abnormal_hematopoietic_stem1.31444955
44MP0000372_irregular_coat_pigmentation1.30005152
45MP0001873_stomach_inflammation1.29581722
46MP0005266_abnormal_metabolism1.29290163
47MP0004742_abnormal_vestibular_system1.26946330
48MP0009785_altered_susceptibility_to1.26942232
49MP0003315_abnormal_perineum_morphology1.26876745
50MP0002019_abnormal_tumor_incidence1.24410314
51MP0008961_abnormal_basal_metabolism1.20809602
52MP0000350_abnormal_cell_proliferation1.19626720
53MP0002254_reproductive_system_inflammat1.12351112
54MP0000313_abnormal_cell_death1.11864583
55MP0002148_abnormal_hypersensitivity_rea1.11806971
56MP0005645_abnormal_hypothalamus_physiol1.09438411
57MP0003787_abnormal_imprinting1.03783478
58MP0003890_abnormal_embryonic-extraembry0.98446547
59MP0001730_embryonic_growth_arrest0.97357930
60MP0002419_abnormal_innate_immunity0.97329188
61MP0002928_abnormal_bile_duct0.93595989
62MP0001845_abnormal_inflammatory_respons0.93276368
63MP0003121_genomic_imprinting0.93256586
64MP0005220_abnormal_exocrine_pancreas0.91555265
65MP0000490_abnormal_crypts_of0.91282467
66MP0002396_abnormal_hematopoietic_system0.89633106
67MP0003786_premature_aging0.88568681
68MP0010155_abnormal_intestine_physiology0.85072363
69MP0009697_abnormal_copulation0.82885357
70MP0003221_abnormal_cardiomyocyte_apopto0.82852625
71MP0004381_abnormal_hair_follicle0.81530542
72MP0003436_decreased_susceptibility_to0.80283196
73MP0002210_abnormal_sex_determination0.79897370
74MP0009672_abnormal_birth_weight0.78920130
75MP0001929_abnormal_gametogenesis0.78427971
76MP0010307_abnormal_tumor_latency0.73742153
77MP0003123_paternal_imprinting0.73728428
78MP0001346_abnormal_lacrimal_gland0.70100599
79MP0002163_abnormal_gland_morphology0.69630960
80MP0000613_abnormal_salivary_gland0.67517530
81MP0002751_abnormal_autonomic_nervous0.66601372
82MP0003868_abnormal_feces_composition0.65441555
83MP0005451_abnormal_body_composition0.65359558
84MP0001145_abnormal_male_reproductive0.65171154
85MP0009333_abnormal_splenocyte_physiolog0.64949225
86MP0003943_abnormal_hepatobiliary_system0.64846847
87MP0009765_abnormal_xenobiotic_induced0.61973580
88MP0004185_abnormal_adipocyte_glucose0.60284195
89MP0000383_abnormal_hair_follicle0.59483830
90MP0003866_abnormal_defecation0.58729390
91MP0003984_embryonic_growth_retardation0.58671753
92MP0005076_abnormal_cell_differentiation0.58471158
93MP0001119_abnormal_female_reproductive0.58151356
94MP0002693_abnormal_pancreas_physiology0.57802972
95MP0001672_abnormal_embryogenesis/_devel0.57228577
96MP0005380_embryogenesis_phenotype0.57228577
97MP0002088_abnormal_embryonic_growth/wei0.56556633
98MP0003091_abnormal_cell_migration0.56459454
99MP0008469_abnormal_protein_level0.56001099
100MP0000653_abnormal_sex_gland0.55642376

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)7.30653716
2Panhypogammaglobulinemia (HP:0003139)4.60783055
3Gastrointestinal stroma tumor (HP:0100723)4.53443274
4Recurrent bronchitis (HP:0002837)4.15083218
5Cellulitis (HP:0100658)3.99999853
6Meningitis (HP:0001287)3.92457732
7Biliary tract neoplasm (HP:0100574)3.90013092
8B lymphocytopenia (HP:0010976)3.70978867
9Colitis (HP:0002583)3.67060683
10Recurrent viral infections (HP:0004429)3.51886417
11Abnormality of the prostate (HP:0008775)3.47071518
12Mediastinal lymphadenopathy (HP:0100721)3.46428876
13Recurrent sinusitis (HP:0011108)3.46416427
14Papilloma (HP:0012740)3.41323079
15Verrucae (HP:0200043)3.41323079
16Colon cancer (HP:0003003)3.39476940
17Lymphopenia (HP:0001888)3.23512269
18Abnormality of B cell number (HP:0010975)3.23121103
19Hypoplastic pelvis (HP:0008839)3.15666230
20Medulloblastoma (HP:0002885)3.02212514
21Recurrent pneumonia (HP:0006532)2.89182757
22Osteomyelitis (HP:0002754)2.82165206
23Abnormality of cells of the lymphoid lineage (HP:0012140)2.80453090
24IgM deficiency (HP:0002850)2.79700666
25Gastrointestinal inflammation (HP:0004386)2.78979844
26Abnormality of male internal genitalia (HP:0000022)2.77271529
27Chronic sinusitis (HP:0011109)2.74673707
28Rhabdomyosarcoma (HP:0002859)2.73494439
29Lymphoma (HP:0002665)2.71625630
30Inflammation of the large intestine (HP:0002037)2.67957821
31Viral hepatitis (HP:0006562)2.67840474
32Recurrent lower respiratory tract infections (HP:0002783)2.67380529
33Abnormal hair whorl (HP:0010721)2.65735718
34Sepsis (HP:0100806)2.56940067
35Basal cell carcinoma (HP:0002671)2.54759177
36Neoplasm of the rectum (HP:0100743)2.53577471
37Bronchitis (HP:0012387)2.49359273
38Neoplasm of the small intestine (HP:0100833)2.48939401
39IgA deficiency (HP:0002720)2.45811743
40Vasculitis (HP:0002633)2.40068913
41Chronic mucocutaneous candidiasis (HP:0002728)2.37851177
42Recurrent cutaneous fungal infections (HP:0011370)2.37851177
43Abnormal delayed hypersensitivity skin test (HP:0002963)2.36535504
44Gastrointestinal carcinoma (HP:0002672)2.34592366
45Malignant gastrointestinal tract tumors (HP:0006749)2.34592366
46Prostate neoplasm (HP:0100787)2.33967770
47Leiomyosarcoma (HP:0100243)2.30888532
48Uterine leiomyosarcoma (HP:0002891)2.30888532
49Poikiloderma (HP:0001029)2.27621272
50Chronic otitis media (HP:0000389)2.27053341
5111 pairs of ribs (HP:0000878)2.27012615
52Recurrent bacterial skin infections (HP:0005406)2.25827162
53Encephalitis (HP:0002383)2.25642014
54Recurrent otitis media (HP:0000403)2.19682589
55Partial agenesis of the corpus callosum (HP:0001338)2.18913633
56Transitional cell carcinoma of the bladder (HP:0006740)2.18510244
57Neoplasm of the colon (HP:0100273)2.15087596
58Neoplasm of striated muscle (HP:0009728)2.14120524
59Abnormal number of erythroid precursors (HP:0012131)2.09402029
60Recurrent fungal infections (HP:0002841)2.07034067
61Bladder neoplasm (HP:0009725)2.06943072
62Bladder carcinoma (HP:0002862)2.06943072
63Prominent nose (HP:0000448)2.03968665
64Recurrent skin infections (HP:0001581)2.03157675
65Abnormality of cells of the erythroid lineage (HP:0012130)2.03110062
66Hypoplasia of the thymus (HP:0000778)2.01893306
67Abnormality of secondary sexual hair (HP:0009888)2.01333317
68Abnormality of the axillary hair (HP:0100134)2.01333317
69Restrictive lung disease (HP:0002091)2.00949137
70IgG deficiency (HP:0004315)2.00614599
71Leukopenia (HP:0001882)1.98744808
72Neutropenia (HP:0001875)1.98661966
73T lymphocytopenia (HP:0005403)1.97860946
74Combined immunodeficiency (HP:0005387)1.97618380
75Primitive neuroectodermal tumor (HP:0030065)1.96317632
76Neuroblastic tumors (HP:0004376)1.96317632
77Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.96317632
78Neuroblastoma (HP:0003006)1.96317632
79Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.94105059
80Abnormality of the right ventricle (HP:0001707)1.91449055
81Abnormality of the anterior horn cell (HP:0006802)1.91236751
82Degeneration of anterior horn cells (HP:0002398)1.91236751
83Emphysema (HP:0002097)1.90833117
84Gonadotropin excess (HP:0000837)1.87790108
85Patellar aplasia (HP:0006443)1.87678809
86Neoplasm of the pancreas (HP:0002894)1.86783617
87Lower limb hyperreflexia (HP:0002395)1.86445396
88Sex reversal (HP:0012245)1.86286456
89Abnormal sex determination (HP:0012244)1.86286456
90Ovarian neoplasm (HP:0100615)1.85401187
91Abnormal biliary tract morphology (HP:0012440)1.82711599
92Generalized aminoaciduria (HP:0002909)1.78357231
93Abnormality of T cells (HP:0002843)1.76035889
94Abnormality of the labia minora (HP:0012880)1.72630562
95Uterine neoplasm (HP:0010784)1.71131193
96Abnormal rod and cone electroretinograms (HP:0008323)1.70312539
97Malignant neoplasm of the central nervous system (HP:0100836)1.69098321
98Skin rash (HP:0000988)1.68825715
99Oligodactyly (hands) (HP:0001180)1.67808852
100Ependymoma (HP:0002888)1.67277189

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K104.63776292
2BLK4.31399899
3MAP4K13.31149040
4RIPK43.29852412
5PASK3.09615080
6CDC72.66291189
7BRSK22.66024456
8WEE12.64167645
9EIF2AK32.27836069
10NEK91.95096890
11KSR11.87730067
12SYK1.84845096
13MAP3K131.83811642
14KSR21.83601114
15MAP3K91.79720433
16VRK21.78953374
17PNCK1.75230944
18CDK41.71527832
19BTK1.68267429
20VRK11.63890441
21TSSK61.51398000
22ERN11.47644816
23NME21.37117904
24TYK21.31986987
25IRAK41.30809224
26TEC1.29026963
27SRPK11.25560057
28MELK1.21365438
29BMPR21.19749574
30ATR1.19233344
31NUAK11.18145661
32CSF1R1.17969947
33MST41.15912346
34CDK121.13608375
35PRPF4B1.13194361
36RAF11.12111302
37LYN1.06874949
38ARAF1.01903739
39SMG11.00751173
40MAP3K21.00251494
41EEF2K0.98055646
42DYRK30.97907674
43CDK30.96184821
44TNK20.93747466
45NLK0.90889197
46EIF2AK20.90325173
47MOS0.87657296
48TAF10.83550791
49IKBKB0.83177099
50NEK10.83156619
51UHMK10.82206203
52IKBKE0.81873521
53MAPK40.80492912
54LRRK20.78396258
55CHUK0.77865073
56TGFBR10.76211359
57GRK60.74911201
58RPS6KA40.74588074
59PLK30.71721496
60BRSK10.70340412
61YES10.70175893
62CDK60.69746686
63PIM10.66729264
64MAP3K140.66608912
65BRD40.64914092
66ACVR1B0.61196627
67SIK20.61028923
68HCK0.59566370
69MKNK10.58665768
70CDK70.57183879
71STK100.56736920
72MAPK110.56495607
73STK160.56131741
74ITK0.55704666
75TTK0.55333056
76NTRK30.54630357
77MAP4K20.54513865
78BMPR1B0.52856595
79TAOK30.51531983
80IRAK20.50860424
81MKNK20.50128291
82CDK80.49066314
83ATM0.43776417
84GRK70.43474904
85TGFBR20.43410873
86CHEK10.42491303
87AURKB0.42346066
88MAP2K20.38781808
89CDK90.38773640
90LCK0.38773264
91PLK10.38441320
92NEK20.36787801
93DYRK1A0.35151552
94SGK20.32620927
95PRKCI0.32439990
96GRK10.31950330
97PRKCQ0.31901416
98MAPK150.30794741
99SIK30.29809129
100MAP2K10.29703262

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034304.04975989
2B cell receptor signaling pathway_Homo sapiens_hsa046623.76577889
3Primary immunodeficiency_Homo sapiens_hsa053403.65118572
4Intestinal immune network for IgA production_Homo sapiens_hsa046723.15652241
5Asthma_Homo sapiens_hsa053103.09763713
6Allograft rejection_Homo sapiens_hsa053302.91186397
7Autoimmune thyroid disease_Homo sapiens_hsa053202.73485612
8DNA replication_Homo sapiens_hsa030302.49566332
9Graft-versus-host disease_Homo sapiens_hsa053322.49122870
10Base excision repair_Homo sapiens_hsa034101.93866856
11Type I diabetes mellitus_Homo sapiens_hsa049401.90762599
12Leishmaniasis_Homo sapiens_hsa051401.86845579
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.82601044
14Antigen processing and presentation_Homo sapiens_hsa046121.82003909
15Cell cycle_Homo sapiens_hsa041101.78024524
16NF-kappa B signaling pathway_Homo sapiens_hsa040641.76679082
17Herpes simplex infection_Homo sapiens_hsa051681.71998151
18Homologous recombination_Homo sapiens_hsa034401.63191235
19Ribosome_Homo sapiens_hsa030101.63080040
20Viral myocarditis_Homo sapiens_hsa054161.62930288
21Proteasome_Homo sapiens_hsa030501.62856951
22Protein export_Homo sapiens_hsa030601.58311304
23Spliceosome_Homo sapiens_hsa030401.57582689
24Epstein-Barr virus infection_Homo sapiens_hsa051691.51451529
25Non-homologous end-joining_Homo sapiens_hsa034501.45658138
26Caffeine metabolism_Homo sapiens_hsa002321.41086574
27Staphylococcus aureus infection_Homo sapiens_hsa051501.40064867
28Colorectal cancer_Homo sapiens_hsa052101.40035630
29Influenza A_Homo sapiens_hsa051641.32662311
30Non-small cell lung cancer_Homo sapiens_hsa052231.27108092
31RNA degradation_Homo sapiens_hsa030181.25953589
32Fanconi anemia pathway_Homo sapiens_hsa034601.23363617
33T cell receptor signaling pathway_Homo sapiens_hsa046601.16479707
34Measles_Homo sapiens_hsa051621.12843665
35Basal transcription factors_Homo sapiens_hsa030221.12578428
36Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.12365017
37Prostate cancer_Homo sapiens_hsa052151.09989912
38Hepatitis B_Homo sapiens_hsa051611.08745454
39Toxoplasmosis_Homo sapiens_hsa051451.08541850
40Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.06262697
41Pyrimidine metabolism_Homo sapiens_hsa002401.06250680
42Hematopoietic cell lineage_Homo sapiens_hsa046401.02501940
43Toll-like receptor signaling pathway_Homo sapiens_hsa046201.01610751
44Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.00895779
45p53 signaling pathway_Homo sapiens_hsa041151.00255182
46RNA polymerase_Homo sapiens_hsa030201.00065915
47Tuberculosis_Homo sapiens_hsa051520.94482929
48Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.94225643
49Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.93225960
50HTLV-I infection_Homo sapiens_hsa051660.89687555
51Osteoclast differentiation_Homo sapiens_hsa043800.89279939
52Apoptosis_Homo sapiens_hsa042100.88395114
53Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.84839084
54Nucleotide excision repair_Homo sapiens_hsa034200.83732902
55Chronic myeloid leukemia_Homo sapiens_hsa052200.81994927
56RNA transport_Homo sapiens_hsa030130.77886812
57Transcriptional misregulation in cancer_Homo sapiens_hsa052020.76541398
58Systemic lupus erythematosus_Homo sapiens_hsa053220.75027612
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.74399484
60One carbon pool by folate_Homo sapiens_hsa006700.73496253
61Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73453029
62Endometrial cancer_Homo sapiens_hsa052130.71020219
63RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.70158712
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70148937
65mRNA surveillance pathway_Homo sapiens_hsa030150.68499848
66Acute myeloid leukemia_Homo sapiens_hsa052210.66831528
67Viral carcinogenesis_Homo sapiens_hsa052030.61679522
68Jak-STAT signaling pathway_Homo sapiens_hsa046300.59251837
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58549576
70Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57008797
71MicroRNAs in cancer_Homo sapiens_hsa052060.56084012
72Renal cell carcinoma_Homo sapiens_hsa052110.55197634
73FoxO signaling pathway_Homo sapiens_hsa040680.54327071
74Purine metabolism_Homo sapiens_hsa002300.49656545
75Pancreatic cancer_Homo sapiens_hsa052120.47545867
76Butanoate metabolism_Homo sapiens_hsa006500.47174156
77Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.45343319
78Oocyte meiosis_Homo sapiens_hsa041140.44135638
79TNF signaling pathway_Homo sapiens_hsa046680.43274740
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.43209469
81Rheumatoid arthritis_Homo sapiens_hsa053230.41548664
82Prolactin signaling pathway_Homo sapiens_hsa049170.41323380
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.40959158
84Hepatitis C_Homo sapiens_hsa051600.37792461
85Glioma_Homo sapiens_hsa052140.35193901
86Drug metabolism - other enzymes_Homo sapiens_hsa009830.34425059
87NOD-like receptor signaling pathway_Homo sapiens_hsa046210.33564920
88Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32391554
89Small cell lung cancer_Homo sapiens_hsa052220.31130985
90Chemokine signaling pathway_Homo sapiens_hsa040620.30328411
91Estrogen signaling pathway_Homo sapiens_hsa049150.28190067
92mTOR signaling pathway_Homo sapiens_hsa041500.26075332
93VEGF signaling pathway_Homo sapiens_hsa043700.25897181
94Choline metabolism in cancer_Homo sapiens_hsa052310.25881750
95Phagosome_Homo sapiens_hsa041450.24764493
96Notch signaling pathway_Homo sapiens_hsa043300.22269369
97Longevity regulating pathway - mammal_Homo sapiens_hsa042110.19997209
98ErbB signaling pathway_Homo sapiens_hsa040120.19640113
99Dorso-ventral axis formation_Homo sapiens_hsa043200.14655917
100Bladder cancer_Homo sapiens_hsa052190.14227321

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