Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.38457843 |
2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.93489888 |
3 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.90529645 |
4 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.90529645 |
5 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.74010443 |
6 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.40237399 |
7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.20784387 |
8 | viral transcription (GO:0019083) | 4.14507895 |
9 | cytidine metabolic process (GO:0046087) | 3.99241512 |
10 | cytidine catabolic process (GO:0006216) | 3.99241512 |
11 | cytidine deamination (GO:0009972) | 3.99241512 |
12 | leukocyte aggregation (GO:0070486) | 3.94983479 |
13 | positive regulation of B cell differentiation (GO:0045579) | 3.94221522 |
14 | translational termination (GO:0006415) | 3.93613723 |
15 | positive T cell selection (GO:0043368) | 3.89358148 |
16 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.87578262 |
17 | mast cell activation (GO:0045576) | 3.85802696 |
18 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.83635923 |
19 | neutrophil activation involved in immune response (GO:0002283) | 3.77009340 |
20 | cellular response to interleukin-15 (GO:0071350) | 3.64335090 |
21 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.62969347 |
22 | detection of bacterium (GO:0016045) | 3.60051136 |
23 | negative regulation of phagocytosis (GO:0050765) | 3.59662496 |
24 | regulation of B cell differentiation (GO:0045577) | 3.59290661 |
25 | detection of other organism (GO:0098543) | 3.58636049 |
26 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.58077619 |
27 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.55516022 |
28 | ribosomal small subunit biogenesis (GO:0042274) | 3.51009397 |
29 | negative regulation of interleukin-12 production (GO:0032695) | 3.50476760 |
30 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.49334326 |
31 | immunoglobulin mediated immune response (GO:0016064) | 3.49070625 |
32 | thymic T cell selection (GO:0045061) | 3.47962128 |
33 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.47563609 |
34 | T cell migration (GO:0072678) | 3.46239722 |
35 | DNA deamination (GO:0045006) | 3.45104138 |
36 | T cell selection (GO:0045058) | 3.43674268 |
37 | translational elongation (GO:0006414) | 3.42361248 |
38 | B cell receptor signaling pathway (GO:0050853) | 3.41429453 |
39 | cotranslational protein targeting to membrane (GO:0006613) | 3.40812614 |
40 | respiratory burst (GO:0045730) | 3.40285242 |
41 | regulation of gamma-delta T cell activation (GO:0046643) | 3.40211739 |
42 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.39852556 |
43 | protein targeting to ER (GO:0045047) | 3.39176904 |
44 | defense response to protozoan (GO:0042832) | 3.27652543 |
45 | regulation of antigen processing and presentation (GO:0002577) | 3.27123315 |
46 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.23376478 |
47 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.23376478 |
48 | regulation of T cell tolerance induction (GO:0002664) | 3.22814773 |
49 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.22056556 |
50 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.21396543 |
51 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.21310153 |
52 | protein localization to endoplasmic reticulum (GO:0070972) | 3.20873076 |
53 | regulation of regulatory T cell differentiation (GO:0045589) | 3.20742138 |
54 | response to protozoan (GO:0001562) | 3.20354283 |
55 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.16573507 |
56 | interferon-gamma production (GO:0032609) | 3.13792253 |
57 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.13785486 |
58 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.10306738 |
59 | regulation of tolerance induction (GO:0002643) | 3.10045022 |
60 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.09253196 |
61 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.08039993 |
62 | viral life cycle (GO:0019058) | 3.05510819 |
63 | response to peptidoglycan (GO:0032494) | 3.05349223 |
64 | myeloid dendritic cell activation (GO:0001773) | 3.04362734 |
65 | negative regulation of T cell mediated immunity (GO:0002710) | 3.03890770 |
66 | cellular extravasation (GO:0045123) | 3.01082766 |
67 | regulation of mast cell degranulation (GO:0043304) | 3.00045230 |
68 | response to interferon-beta (GO:0035456) | 2.99560888 |
69 | B cell mediated immunity (GO:0019724) | 2.98695153 |
70 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.98003654 |
71 | T cell receptor signaling pathway (GO:0050852) | 2.97206873 |
72 | neutrophil activation (GO:0042119) | 2.96080225 |
73 | mast cell activation involved in immune response (GO:0002279) | 2.95819793 |
74 | mast cell degranulation (GO:0043303) | 2.95819793 |
75 | T cell homeostasis (GO:0043029) | 2.95403452 |
76 | cellular protein complex disassembly (GO:0043624) | 2.95196327 |
77 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.93836350 |
78 | microglial cell activation (GO:0001774) | 2.93558025 |
79 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.93515505 |
80 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.92367365 |
81 | negative regulation of T cell apoptotic process (GO:0070233) | 2.92359436 |
82 | Peyers patch development (GO:0048541) | 2.91751985 |
83 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.91751985 |
84 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.90800956 |
85 | negative regulation of cell killing (GO:0031342) | 2.90783820 |
86 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.90783820 |
87 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.90519058 |
88 | macrophage activation involved in immune response (GO:0002281) | 2.88443952 |
89 | regulation of mast cell activation (GO:0033003) | 2.87448432 |
90 | detection of external biotic stimulus (GO:0098581) | 2.87297547 |
91 | positive regulation of tolerance induction (GO:0002645) | 2.87113090 |
92 | maturation of SSU-rRNA (GO:0030490) | 2.86772787 |
93 | T cell costimulation (GO:0031295) | 2.85841317 |
94 | negative T cell selection (GO:0043383) | 2.85324817 |
95 | cellular response to zinc ion (GO:0071294) | 2.82866861 |
96 | DNA strand elongation (GO:0022616) | 2.82600497 |
97 | lymphocyte costimulation (GO:0031294) | 2.82209164 |
98 | myeloid cell activation involved in immune response (GO:0002275) | 2.82099919 |
99 | lymphocyte chemotaxis (GO:0048247) | 2.81426668 |
100 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.81240173 |
101 | positive regulation of mast cell activation (GO:0033005) | 2.80349225 |
102 | response to type I interferon (GO:0034340) | 2.80301801 |
103 | type I interferon signaling pathway (GO:0060337) | 2.79734899 |
104 | cellular response to type I interferon (GO:0071357) | 2.79734899 |
105 | cellular response to interferon-beta (GO:0035458) | 2.79525257 |
106 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.79369535 |
107 | granulocyte activation (GO:0036230) | 2.78863043 |
108 | negative regulation of innate immune response (GO:0045824) | 2.78806772 |
109 | positive regulation of macrophage differentiation (GO:0045651) | 2.78719587 |
110 | telomere maintenance via recombination (GO:0000722) | 2.78457721 |
111 | mature B cell differentiation involved in immune response (GO:0002313) | 2.78066718 |
112 | actin nucleation (GO:0045010) | 2.77187090 |
113 | response to host immune response (GO:0052572) | 2.77138558 |
114 | translational initiation (GO:0006413) | 2.76068204 |
115 | negative thymic T cell selection (GO:0045060) | 2.72473776 |
116 | leukocyte degranulation (GO:0043299) | 2.71743562 |
117 | definitive hemopoiesis (GO:0060216) | 2.69701628 |
118 | protein complex disassembly (GO:0043241) | 2.63583290 |
119 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.59311785 |
120 | positive regulation of isotype switching (GO:0045830) | 2.59301589 |
121 | lymphocyte homeostasis (GO:0002260) | 2.59120958 |
122 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.58008872 |
123 | positive thymic T cell selection (GO:0045059) | 2.57133705 |
124 | positive regulation of lamellipodium assembly (GO:0010592) | 2.57017600 |
125 | positive regulation of granulocyte differentiation (GO:0030854) | 2.55482612 |
126 | response to interleukin-15 (GO:0070672) | 2.54489168 |
127 | megakaryocyte development (GO:0035855) | 2.54395764 |
128 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.54094522 |
129 | myeloid dendritic cell differentiation (GO:0043011) | 2.53559681 |
130 | positive regulation of antigen processing and presentation (GO:0002579) | 2.51518199 |
131 | mitotic recombination (GO:0006312) | 2.51156333 |
132 | NIK/NF-kappaB signaling (GO:0038061) | 2.50495391 |
133 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.50002680 |
134 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.48224293 |
135 | modulation by symbiont of host immune response (GO:0052553) | 2.48224293 |
136 | positive regulation by symbiont of host defense response (GO:0052509) | 2.48224293 |
137 | modulation by symbiont of host defense response (GO:0052031) | 2.48224293 |
138 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.48224293 |
139 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.48224293 |
140 | leukocyte cell-cell adhesion (GO:0007159) | 2.44579019 |
141 | pinocytosis (GO:0006907) | 2.44338430 |
142 | macromolecular complex disassembly (GO:0032984) | 2.44289457 |
143 | mature B cell differentiation (GO:0002335) | 2.44281080 |
144 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.42805417 |
145 | neutrophil mediated immunity (GO:0002446) | 2.41378732 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.86986356 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.97061270 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.44010317 |
4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.34929156 |
5 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.30904939 |
6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.27282629 |
7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.05220771 |
8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.03782202 |
9 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.94939564 |
10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.84630464 |
11 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.83393642 |
12 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.66297679 |
13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.62216772 |
14 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.61445075 |
15 | * RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.57510636 |
16 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.46018350 |
17 | MYC_22102868_ChIP-Seq_BL_Human | 2.44259785 |
18 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.39090791 |
19 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.38287265 |
20 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.37632909 |
21 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.36289340 |
22 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.25545993 |
23 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.24166888 |
24 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.22936272 |
25 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.20589366 |
26 | MYB_26560356_Chip-Seq_TH2_Human | 2.19739087 |
27 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.18615667 |
28 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.18471744 |
29 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.16296573 |
30 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.14481437 |
31 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 2.03075003 |
32 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.99976277 |
33 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.96071920 |
34 | MAF_26560356_Chip-Seq_TH1_Human | 1.95957219 |
35 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.89301025 |
36 | MYB_26560356_Chip-Seq_TH1_Human | 1.86341267 |
37 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.85630957 |
38 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.84281608 |
39 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.83121535 |
40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.83077603 |
41 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.80782917 |
42 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.79091034 |
43 | UTX_26944678_Chip-Seq_JUKART_Human | 1.76668237 |
44 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.75833396 |
45 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.74371056 |
46 | * MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.72308113 |
47 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.69816863 |
48 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.69312839 |
49 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.69263849 |
50 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.67799014 |
51 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.67602313 |
52 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.65772207 |
53 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.60120285 |
54 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.55676836 |
55 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.55632845 |
56 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53685881 |
57 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.48060742 |
58 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.47217840 |
59 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.46126393 |
60 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.44845755 |
61 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.44278004 |
62 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.39556128 |
63 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.35696652 |
64 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.34269762 |
65 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.33841937 |
66 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.33827444 |
67 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.33373598 |
68 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.33203022 |
69 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.31847855 |
70 | MAF_26560356_Chip-Seq_TH2_Human | 1.30849309 |
71 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.29656461 |
72 | SPI1_23127762_ChIP-Seq_K562_Human | 1.28401453 |
73 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.28305298 |
74 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.27824528 |
75 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.27773062 |
76 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.25801989 |
77 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.24018691 |
78 | GATA1_22025678_ChIP-Seq_K562_Human | 1.23015208 |
79 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.21928287 |
80 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.20757824 |
81 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.19962632 |
82 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.18203111 |
83 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.18159020 |
84 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.16589811 |
85 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15627409 |
86 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.14054558 |
87 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.12463317 |
88 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.11036268 |
89 | * PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08615173 |
90 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08571169 |
91 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08420361 |
92 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.08123966 |
93 | P300_27268052_Chip-Seq_Bcells_Human | 1.07390967 |
94 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.07216818 |
95 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.06644780 |
96 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.04225529 |
97 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.02985907 |
98 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.02448622 |
99 | GATA1_19941826_ChIP-Seq_K562_Human | 1.02122901 |
100 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.01478433 |
101 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.01263179 |
102 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.01234582 |
103 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.00883889 |
104 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.00767035 |
105 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98833083 |
106 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.97394791 |
107 | GATA3_26560356_Chip-Seq_TH2_Human | 0.96292356 |
108 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.95290696 |
109 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95234218 |
110 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.94702214 |
111 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94460227 |
112 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.94329924 |
113 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.94131459 |
114 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.93984344 |
115 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.93924600 |
116 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.93087085 |
117 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.92728085 |
118 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.90470662 |
119 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.90268793 |
120 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.90201616 |
121 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.89788901 |
122 | * SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.89336737 |
123 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.89318918 |
124 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89231125 |
125 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.87470181 |
126 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86696809 |
127 | * RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84618703 |
128 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.84399098 |
129 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.81145837 |
130 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.80529941 |
131 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.78414212 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 4.18280006 |
2 | MP0009785_altered_susceptibility_to | 3.43751166 |
3 | MP0005671_abnormal_response_to | 3.37018498 |
4 | MP0002396_abnormal_hematopoietic_system | 3.18490446 |
5 | MP0003436_decreased_susceptibility_to | 3.10830120 |
6 | MP0000685_abnormal_immune_system | 3.06748060 |
7 | MP0001800_abnormal_humoral_immune | 2.90537033 |
8 | MP0003763_abnormal_thymus_physiology | 2.85982319 |
9 | MP0005000_abnormal_immune_tolerance | 2.84663630 |
10 | MP0005025_abnormal_response_to | 2.82306083 |
11 | MP0002148_abnormal_hypersensitivity_rea | 2.75783938 |
12 | MP0002452_abnormal_antigen_presenting | 2.68943088 |
13 | MP0002420_abnormal_adaptive_immunity | 2.65251846 |
14 | MP0002419_abnormal_innate_immunity | 2.64788560 |
15 | MP0001819_abnormal_immune_cell | 2.62660450 |
16 | MP0002723_abnormal_immune_serum | 2.62367578 |
17 | MP0005387_immune_system_phenotype | 2.55306343 |
18 | MP0001790_abnormal_immune_system | 2.55306343 |
19 | MP0002398_abnormal_bone_marrow | 2.51535307 |
20 | MP0003724_increased_susceptibility_to | 2.51299932 |
21 | MP0005464_abnormal_platelet_physiology | 2.41700619 |
22 | MP0002166_altered_tumor_susceptibility | 2.33837947 |
23 | MP0009333_abnormal_splenocyte_physiolog | 2.25586766 |
24 | MP0000716_abnormal_immune_system | 2.24672603 |
25 | MP0002405_respiratory_system_inflammati | 2.12781549 |
26 | MP0000689_abnormal_spleen_morphology | 2.10043847 |
27 | MP0005397_hematopoietic_system_phenotyp | 2.07920811 |
28 | MP0001545_abnormal_hematopoietic_system | 2.07920811 |
29 | MP0004808_abnormal_hematopoietic_stem | 2.07494172 |
30 | MP0002006_tumorigenesis | 2.06849705 |
31 | MP0002722_abnormal_immune_system | 2.05412770 |
32 | MP0003303_peritoneal_inflammation | 2.05017316 |
33 | MP0001853_heart_inflammation | 2.01435256 |
34 | MP0010155_abnormal_intestine_physiology | 1.97382375 |
35 | MP0002429_abnormal_blood_cell | 1.96717371 |
36 | MP0005174_abnormal_tail_pigmentation | 1.86204756 |
37 | MP0006082_CNS_inflammation | 1.79632567 |
38 | MP0003693_abnormal_embryo_hatching | 1.78278252 |
39 | MP0000703_abnormal_thymus_morphology | 1.76816707 |
40 | MP0000490_abnormal_crypts_of | 1.76142153 |
41 | MP0001845_abnormal_inflammatory_respons | 1.75837722 |
42 | MP0003806_abnormal_nucleotide_metabolis | 1.69270465 |
43 | MP0000465_gastrointestinal_hemorrhage | 1.68635835 |
44 | MP0001873_stomach_inflammation | 1.67421912 |
45 | MP0010094_abnormal_chromosome_stability | 1.66143418 |
46 | MP0009278_abnormal_bone_marrow | 1.65064270 |
47 | MP0008057_abnormal_DNA_replication | 1.53605384 |
48 | MP0004947_skin_inflammation | 1.48095797 |
49 | MP0001533_abnormal_skeleton_physiology | 1.47736883 |
50 | MP0000858_altered_metastatic_potential | 1.47106823 |
51 | MP0003866_abnormal_defecation | 1.45571784 |
52 | MP0008469_abnormal_protein_level | 1.41032162 |
53 | MP0005075_abnormal_melanosome_morpholog | 1.40610794 |
54 | MP0002138_abnormal_hepatobiliary_system | 1.34742295 |
55 | MP0003077_abnormal_cell_cycle | 1.30880474 |
56 | MP0002019_abnormal_tumor_incidence | 1.26021139 |
57 | MP0000343_altered_response_to | 1.19016862 |
58 | MP0003300_gastrointestinal_ulcer | 1.18319163 |
59 | MP0008007_abnormal_cellular_replicative | 1.16810790 |
60 | MP0003191_abnormal_cellular_cholesterol | 1.16631062 |
61 | MP0005058_abnormal_lysosome_morphology | 1.15832365 |
62 | MP0003111_abnormal_nucleus_morphology | 1.15006908 |
63 | MP0008058_abnormal_DNA_repair | 1.14698836 |
64 | MP0003448_altered_tumor_morphology | 1.12400670 |
65 | MP0002095_abnormal_skin_pigmentation | 1.11653469 |
66 | MP0004957_abnormal_blastocyst_morpholog | 1.07673561 |
67 | MP0002933_joint_inflammation | 1.07097456 |
68 | MP0006054_spinal_hemorrhage | 1.05754722 |
69 | MP0009764_decreased_sensitivity_to | 1.05617611 |
70 | MP0002132_abnormal_respiratory_system | 1.02799581 |
71 | MP0000015_abnormal_ear_pigmentation | 1.01391165 |
72 | MP0003172_abnormal_lysosome_physiology | 0.99046743 |
73 | MP0010352_gastrointestinal_tract_polyps | 0.93937866 |
74 | MP0002277_abnormal_respiratory_mucosa | 0.93702217 |
75 | MP0004510_myositis | 0.93482282 |
76 | MP0005310_abnormal_salivary_gland | 0.90152593 |
77 | MP0003045_fibrosis | 0.90142527 |
78 | MP0003186_abnormal_redox_activity | 0.86389676 |
79 | MP0010307_abnormal_tumor_latency | 0.85945948 |
80 | MP0001851_eye_inflammation | 0.82416057 |
81 | MP0009763_increased_sensitivity_to | 0.82131524 |
82 | MP0003183_abnormal_peptide_metabolism | 0.82116261 |
83 | MP0000313_abnormal_cell_death | 0.80252846 |
84 | MP0000604_amyloidosis | 0.80091520 |
85 | MP0003656_abnormal_erythrocyte_physiolo | 0.79874536 |
86 | MP0003075_altered_response_to | 0.79248574 |
87 | MP0004883_abnormal_blood_vessel | 0.75072950 |
88 | MP0001986_abnormal_taste_sensitivity | 0.72314674 |
89 | MP0001663_abnormal_digestive_system | 0.72154676 |
90 | MP0005166_decreased_susceptibility_to | 0.71023961 |
91 | MP0005451_abnormal_body_composition | 0.69882066 |
92 | MP0003828_pulmonary_edema | 0.69028795 |
93 | MP0002998_abnormal_bone_remodeling | 0.68159013 |
94 | MP0009379_abnormal_foot_pigmentation | 0.64920745 |
95 | MP0008873_increased_physiological_sensi | 0.63883702 |
96 | MP0005645_abnormal_hypothalamus_physiol | 0.63173479 |
97 | MP0002693_abnormal_pancreas_physiology | 0.61935876 |
98 | MP0008004_abnormal_stomach_pH | 0.61651676 |
99 | MP0000249_abnormal_blood_vessel | 0.61224389 |
100 | MP0005164_abnormal_response_to | 0.60694845 |
101 | MP0005084_abnormal_gallbladder_morpholo | 0.56629504 |
102 | MP0005390_skeleton_phenotype | 0.56040324 |
103 | MP0005319_abnormal_enzyme/_coenzyme | 0.55798897 |
104 | MP0009765_abnormal_xenobiotic_induced | 0.55400109 |
105 | MP0008260_abnormal_autophagy | 0.54990545 |
106 | MP0006036_abnormal_mitochondrial_physio | 0.53877563 |
107 | MP0000371_diluted_coat_color | 0.53404823 |
108 | MP0004381_abnormal_hair_follicle | 0.53394472 |
109 | MP0000477_abnormal_intestine_morphology | 0.52778344 |
110 | MP0003943_abnormal_hepatobiliary_system | 0.52532980 |
111 | MP0003786_premature_aging | 0.51610961 |
112 | MP0002009_preneoplasia | 0.51506031 |
113 | MP0000350_abnormal_cell_proliferation | 0.51270131 |
114 | MP0001764_abnormal_homeostasis | 0.50359850 |
115 | MP0005409_darkened_coat_color | 0.50175981 |
116 | MP0003795_abnormal_bone_structure | 0.50124790 |
117 | MP0009840_abnormal_foam_cell | 0.49091130 |
118 | MP0003646_muscle_fatigue | 0.49068822 |
119 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.48995835 |
120 | MP0008874_decreased_physiological_sensi | 0.48407070 |
121 | MP0005167_abnormal_blood-brain_barrier | 0.47425580 |
122 | MP0003690_abnormal_glial_cell | 0.46654052 |
123 | MP0003252_abnormal_bile_duct | 0.46384901 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 5.58857240 |
2 | Recurrent bacterial skin infections (HP:0005406) | 4.86416508 |
3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.68247489 |
4 | Eczematoid dermatitis (HP:0000976) | 4.63744513 |
5 | Myositis (HP:0100614) | 4.26432416 |
6 | IgM deficiency (HP:0002850) | 4.19998061 |
7 | Thrombocytosis (HP:0001894) | 4.05333252 |
8 | Recurrent viral infections (HP:0004429) | 4.03588621 |
9 | Recurrent fungal infections (HP:0002841) | 3.96099892 |
10 | Chronic otitis media (HP:0000389) | 3.88192602 |
11 | Meningitis (HP:0001287) | 3.73426158 |
12 | Increased IgM level (HP:0003496) | 3.66181587 |
13 | Panhypogammaglobulinemia (HP:0003139) | 3.63044140 |
14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.61264392 |
15 | Abnormal number of erythroid precursors (HP:0012131) | 3.60719062 |
16 | Petechiae (HP:0000967) | 3.58757867 |
17 | T lymphocytopenia (HP:0005403) | 3.58748697 |
18 | Cellulitis (HP:0100658) | 3.54119663 |
19 | Recurrent bronchitis (HP:0002837) | 3.53953284 |
20 | Abnormality of B cell number (HP:0010975) | 3.53351041 |
21 | B lymphocytopenia (HP:0010976) | 3.53351041 |
22 | Mediastinal lymphadenopathy (HP:0100721) | 3.52263606 |
23 | Abnormality of T cells (HP:0002843) | 3.48847640 |
24 | Abnormality of T cell number (HP:0011839) | 3.48210337 |
25 | Reticulocytopenia (HP:0001896) | 3.46149301 |
26 | Chronic obstructive pulmonary disease (HP:0006510) | 3.41305795 |
27 | Obstructive lung disease (HP:0006536) | 3.41305795 |
28 | Recurrent skin infections (HP:0001581) | 3.38671055 |
29 | Agammaglobulinemia (HP:0004432) | 3.32193277 |
30 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.31500995 |
31 | Thyroiditis (HP:0100646) | 3.25117875 |
32 | Abnormality of T cell physiology (HP:0011840) | 3.22866384 |
33 | Abnormality of macrophages (HP:0004311) | 3.19805474 |
34 | Severe combined immunodeficiency (HP:0004430) | 3.14472370 |
35 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.08608799 |
36 | Gastrointestinal infarctions (HP:0005244) | 3.08548516 |
37 | IgG deficiency (HP:0004315) | 3.06447426 |
38 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.99310632 |
39 | Recurrent cutaneous fungal infections (HP:0011370) | 2.99310632 |
40 | Combined immunodeficiency (HP:0005387) | 2.99101517 |
41 | Aplastic anemia (HP:0001915) | 2.99063031 |
42 | Prolonged bleeding time (HP:0003010) | 2.97660544 |
43 | Stomatitis (HP:0010280) | 2.96963678 |
44 | Spontaneous hematomas (HP:0007420) | 2.95472259 |
45 | Eosinophilia (HP:0001880) | 2.84604318 |
46 | Orchitis (HP:0100796) | 2.81018199 |
47 | Lymphopenia (HP:0001888) | 2.80985749 |
48 | Pustule (HP:0200039) | 2.78780764 |
49 | Keratoconjunctivitis (HP:0001096) | 2.77914926 |
50 | Granulocytopenia (HP:0001913) | 2.77457112 |
51 | Vasculitis (HP:0002633) | 2.76694954 |
52 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.76314556 |
53 | Nasal polyposis (HP:0100582) | 2.74756745 |
54 | Leukocytosis (HP:0001974) | 2.73645853 |
55 | Autoimmune thrombocytopenia (HP:0001973) | 2.72778370 |
56 | Abnormality of the prostate (HP:0008775) | 2.69750923 |
57 | Abnormality of eosinophils (HP:0001879) | 2.68100993 |
58 | Optic neuritis (HP:0100653) | 2.66112534 |
59 | Retrobulbar optic neuritis (HP:0100654) | 2.66112534 |
60 | Epistaxis (HP:0000421) | 2.63674385 |
61 | Inflammation of the large intestine (HP:0002037) | 2.63527377 |
62 | Gastrointestinal inflammation (HP:0004386) | 2.60449856 |
63 | Hypoplasia of the thymus (HP:0000778) | 2.56915260 |
64 | Vacuolated lymphocytes (HP:0001922) | 2.56781243 |
65 | Lymphoma (HP:0002665) | 2.54389644 |
66 | Abnormality of the nasal mucosa (HP:0000433) | 2.53478410 |
67 | Abnormality of glycolipid metabolism (HP:0010969) | 2.49420067 |
68 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.49420067 |
69 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.49420067 |
70 | Encephalitis (HP:0002383) | 2.47687910 |
71 | Arterial thrombosis (HP:0004420) | 2.44804948 |
72 | Osteomyelitis (HP:0002754) | 2.43588609 |
73 | Abnormality of the pleura (HP:0002103) | 2.43262970 |
74 | Pulmonary embolism (HP:0002204) | 2.42878706 |
75 | Gingivitis (HP:0000230) | 2.42695169 |
76 | Pallor (HP:0000980) | 2.42391478 |
77 | Gangrene (HP:0100758) | 2.38032313 |
78 | Interstitial pulmonary disease (HP:0006530) | 2.36931800 |
79 | Increased serum ferritin (HP:0003281) | 2.36663666 |
80 | Recurrent pneumonia (HP:0006532) | 2.33065457 |
81 | Increased cerebral lipofuscin (HP:0011813) | 2.32333579 |
82 | Skin rash (HP:0000988) | 2.32255339 |
83 | Agnosia (HP:0010524) | 2.32108634 |
84 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.28329194 |
85 | Sepsis (HP:0100806) | 2.27677671 |
86 | Joint swelling (HP:0001386) | 2.25682249 |
87 | Periodontitis (HP:0000704) | 2.24881145 |
88 | Poikiloderma (HP:0001029) | 2.24869351 |
89 | Hemoptysis (HP:0002105) | 2.24298758 |
90 | Hypergammaglobulinemia (HP:0010702) | 2.23988708 |
91 | Reduced antithrombin III activity (HP:0001976) | 2.22277875 |
92 | Recurrent sinusitis (HP:0011108) | 2.22006199 |
93 | Colitis (HP:0002583) | 2.21386528 |
94 | Abnormality of iron homeostasis (HP:0011031) | 2.21228939 |
95 | Hypochromic anemia (HP:0001931) | 2.20411060 |
96 | Pulmonary infiltrates (HP:0002113) | 2.19057287 |
97 | Anorexia (HP:0002039) | 2.18804074 |
98 | Verrucae (HP:0200043) | 2.16316810 |
99 | Papilloma (HP:0012740) | 2.16316810 |
100 | Episodic fever (HP:0001954) | 2.16208954 |
101 | Recurrent lower respiratory tract infections (HP:0002783) | 2.16100153 |
102 | Impaired platelet aggregation (HP:0003540) | 2.14985996 |
103 | Abnormal platelet function (HP:0011869) | 2.14985996 |
104 | Basal ganglia calcification (HP:0002135) | 2.12645598 |
105 | Acute hepatic failure (HP:0006554) | 2.12261107 |
106 | Autoimmune hemolytic anemia (HP:0001890) | 2.11383198 |
107 | Macrocytic anemia (HP:0001972) | 2.10466678 |
108 | Keratoconjunctivitis sicca (HP:0001097) | 2.10310641 |
109 | Purpura (HP:0000979) | 2.09899957 |
110 | Skin ulcer (HP:0200042) | 2.08776929 |
111 | Hepatosplenomegaly (HP:0001433) | 2.08199313 |
112 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.07893708 |
113 | Neutropenia (HP:0001875) | 2.06900647 |
114 | Chest pain (HP:0100749) | 2.06581664 |
115 | Increased IgE level (HP:0003212) | 2.05386720 |
116 | Gastrointestinal stroma tumor (HP:0100723) | 2.04763345 |
117 | Urticaria (HP:0001025) | 2.04552972 |
118 | Hypoproteinemia (HP:0003075) | 2.03937518 |
119 | Gingival bleeding (HP:0000225) | 2.03081061 |
120 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.01491074 |
121 | Chronic diarrhea (HP:0002028) | 1.98166785 |
122 | Chronic sinusitis (HP:0011109) | 1.98029720 |
123 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.97835596 |
124 | Polyneuropathy (HP:0001271) | 1.97543748 |
125 | Glomerulopathy (HP:0100820) | 1.95141350 |
126 | Pulmonary fibrosis (HP:0002206) | 1.94996736 |
127 | Stomach cancer (HP:0012126) | 1.91336311 |
128 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.91191918 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 4.21962754 |
2 | TXK | 3.01379699 |
3 | BLK | 2.94313642 |
4 | KIT | 2.64011634 |
5 | TEC | 2.56157688 |
6 | BTK | 2.47325990 |
7 | IRAK4 | 2.42973748 |
8 | ZAP70 | 2.24215587 |
9 | NME2 | 2.21073366 |
10 | TYK2 | 1.99665698 |
11 | TBK1 | 1.99131201 |
12 | JAK3 | 1.88131607 |
13 | IKBKE | 1.84823205 |
14 | SYK | 1.83149656 |
15 | CSF1R | 1.80743939 |
16 | MAP3K14 | 1.80646457 |
17 | EEF2K | 1.75960694 |
18 | FLT3 | 1.75949743 |
19 | MAP3K10 | 1.68643823 |
20 | ITK | 1.68234540 |
21 | PIM2 | 1.65961248 |
22 | GRK6 | 1.57232081 |
23 | STK10 | 1.56588418 |
24 | STK16 | 1.55766658 |
25 | BCKDK | 1.49511391 |
26 | CLK1 | 1.47109195 |
27 | RIPK4 | 1.44734418 |
28 | MAP3K12 | 1.44267947 |
29 | WEE1 | 1.40712915 |
30 | MAP2K3 | 1.39972842 |
31 | BMPR2 | 1.38266534 |
32 | FES | 1.36464797 |
33 | PIM1 | 1.34814381 |
34 | LCK | 1.34414543 |
35 | KDR | 1.33614178 |
36 | IKBKB | 1.33267885 |
37 | LYN | 1.28655513 |
38 | LRRK2 | 1.26893881 |
39 | TESK2 | 1.21779908 |
40 | ACVR1B | 1.19769049 |
41 | TAOK3 | 1.19448693 |
42 | HCK | 1.19067862 |
43 | CDC7 | 1.16782608 |
44 | ERN1 | 1.16280710 |
45 | NLK | 1.13634112 |
46 | TGFBR1 | 1.13129878 |
47 | CSK | 1.10869381 |
48 | PRKCQ | 1.10543986 |
49 | MST4 | 1.10035905 |
50 | IRAK3 | 1.08989085 |
51 | GRK7 | 1.06197568 |
52 | NEK2 | 1.05913009 |
53 | SCYL2 | 1.04903149 |
54 | EIF2AK3 | 1.01225426 |
55 | VRK2 | 0.99345666 |
56 | RPS6KA4 | 0.98789814 |
57 | VRK1 | 0.98705572 |
58 | TLK1 | 0.98254146 |
59 | RPS6KB2 | 0.95690608 |
60 | JAK1 | 0.93625957 |
61 | STK4 | 0.92615908 |
62 | TGFBR2 | 0.92274378 |
63 | BUB1 | 0.89753558 |
64 | FGR | 0.88887480 |
65 | EIF2AK1 | 0.88158284 |
66 | BRSK2 | 0.87182537 |
67 | MATK | 0.82541107 |
68 | PKN2 | 0.80464720 |
69 | CDK4 | 0.78358433 |
70 | TNK2 | 0.74776673 |
71 | CAMKK2 | 0.73614234 |
72 | ATR | 0.71476785 |
73 | PRPF4B | 0.70646380 |
74 | MAP3K3 | 0.68976314 |
75 | MAP2K6 | 0.68519120 |
76 | NUAK1 | 0.66213788 |
77 | TAOK2 | 0.65778816 |
78 | MAPK4 | 0.65406443 |
79 | DYRK3 | 0.63534013 |
80 | SIK2 | 0.63355181 |
81 | MAP3K1 | 0.60850632 |
82 | TNIK | 0.60082082 |
83 | SRPK1 | 0.58180329 |
84 | CDK7 | 0.57449066 |
85 | PDK1 | 0.57231988 |
86 | JAK2 | 0.57160457 |
87 | RPS6KA6 | 0.56782354 |
88 | PASK | 0.56430667 |
89 | MAP4K2 | 0.56395024 |
90 | FYN | 0.55655795 |
91 | FGFR4 | 0.54756770 |
92 | SIK3 | 0.54021081 |
93 | NEK9 | 0.53763573 |
94 | PAK4 | 0.53393027 |
95 | FGFR3 | 0.52905327 |
96 | CHUK | 0.52347430 |
97 | MAP2K2 | 0.51344525 |
98 | ADRBK2 | 0.50804574 |
99 | TRPM7 | 0.49828257 |
100 | CDK19 | 0.49031138 |
101 | IRAK1 | 0.48740268 |
102 | MAP3K11 | 0.48146834 |
103 | RPS6KC1 | 0.47417133 |
104 | RPS6KL1 | 0.47417133 |
105 | MARK3 | 0.47076195 |
106 | TAOK1 | 0.46481165 |
107 | MAPK11 | 0.46452715 |
108 | MKNK1 | 0.45336087 |
109 | MAP3K13 | 0.45202794 |
110 | TESK1 | 0.44421888 |
111 | YES1 | 0.44085409 |
112 | CCNB1 | 0.42379181 |
113 | DAPK1 | 0.41845525 |
114 | EIF2AK2 | 0.41744347 |
115 | MAPKAPK3 | 0.41604408 |
116 | EPHB1 | 0.40231862 |
117 | MAPK12 | 0.40231552 |
118 | AURKB | 0.39936520 |
119 | PRKCD | 0.39472600 |
120 | MAP3K8 | 0.39410858 |
121 | CDK8 | 0.39290437 |
122 | CAMKK1 | 0.39100097 |
123 | MAP3K5 | 0.38691699 |
124 | ABL1 | 0.38314099 |
125 | ZAK | 0.37825981 |
126 | ILK | 0.37655167 |
127 | PIK3CG | 0.36730324 |
128 | MAPKAPK2 | 0.34577897 |
129 | GRK5 | 0.33601037 |
130 | HIPK2 | 0.32568951 |
131 | IGF1R | 0.31707911 |
132 | RPS6KA5 | 0.30731264 |
133 | MAPK7 | 0.28207598 |
134 | ADRBK1 | 0.28062647 |
135 | MAPK3 | 0.26958494 |
136 | DAPK2 | 0.26518759 |
137 | GRK1 | 0.21296869 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.60943719 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.35002143 |
3 | Ribosome_Homo sapiens_hsa03010 | 3.31469726 |
4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.47241038 |
5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.41855757 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 2.37729770 |
7 | Base excision repair_Homo sapiens_hsa03410 | 2.18402182 |
8 | Measles_Homo sapiens_hsa05162 | 2.07927201 |
9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.07421647 |
10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.05071464 |
11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.03803345 |
12 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.01730228 |
13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.00760711 |
14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.99320157 |
15 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.91253383 |
16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.85376861 |
17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.84993979 |
18 | Allograft rejection_Homo sapiens_hsa05330 | 1.82162851 |
19 | Homologous recombination_Homo sapiens_hsa03440 | 1.81626580 |
20 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.75496919 |
21 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.72979123 |
22 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.72709375 |
23 | Legionellosis_Homo sapiens_hsa05134 | 1.59219842 |
24 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.57560178 |
25 | Spliceosome_Homo sapiens_hsa03040 | 1.55703030 |
26 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.49222734 |
27 | Proteasome_Homo sapiens_hsa03050 | 1.48634594 |
28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.46735825 |
29 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.43504651 |
30 | Asthma_Homo sapiens_hsa05310 | 1.43009405 |
31 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.42742649 |
32 | Pertussis_Homo sapiens_hsa05133 | 1.37796921 |
33 | Other glycan degradation_Homo sapiens_hsa00511 | 1.32753486 |
34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.30092145 |
35 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.25864977 |
36 | Shigellosis_Homo sapiens_hsa05131 | 1.24880480 |
37 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.23604024 |
38 | Influenza A_Homo sapiens_hsa05164 | 1.21090973 |
39 | Tuberculosis_Homo sapiens_hsa05152 | 1.19633195 |
40 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.17928379 |
41 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.13056716 |
42 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.11724806 |
43 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.11331206 |
44 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.08958745 |
45 | RNA polymerase_Homo sapiens_hsa03020 | 1.08637566 |
46 | Apoptosis_Homo sapiens_hsa04210 | 1.08211728 |
47 | Malaria_Homo sapiens_hsa05144 | 1.08176496 |
48 | Hepatitis B_Homo sapiens_hsa05161 | 1.07023110 |
49 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.02770548 |
50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.01734701 |
51 | Cell cycle_Homo sapiens_hsa04110 | 0.99747686 |
52 | Salmonella infection_Homo sapiens_hsa05132 | 0.99139067 |
53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.98173697 |
54 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.97320982 |
55 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.96624335 |
56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.95844903 |
57 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.94933735 |
58 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.92088187 |
59 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.91198162 |
60 | Platelet activation_Homo sapiens_hsa04611 | 0.90084997 |
61 | Viral myocarditis_Homo sapiens_hsa05416 | 0.88146865 |
62 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.87161747 |
63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.86575599 |
64 | RNA degradation_Homo sapiens_hsa03018 | 0.86047866 |
65 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.85169762 |
66 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.77861518 |
67 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.75428267 |
68 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.72388562 |
69 | Protein export_Homo sapiens_hsa03060 | 0.71804697 |
70 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.67870327 |
71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.67605445 |
72 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.66149265 |
73 | RNA transport_Homo sapiens_hsa03013 | 0.65516061 |
74 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.63339465 |
75 | HTLV-I infection_Homo sapiens_hsa05166 | 0.62881649 |
76 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.61548632 |
77 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59079139 |
78 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.57822204 |
79 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56757019 |
80 | Lysosome_Homo sapiens_hsa04142 | 0.56290607 |
81 | Hepatitis C_Homo sapiens_hsa05160 | 0.56278508 |
82 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.54630285 |
83 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.53005957 |
84 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.52763082 |
85 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52710120 |
86 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.51593247 |
87 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.51166471 |
88 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.50788404 |
89 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.50506586 |
90 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.50264267 |
91 | Purine metabolism_Homo sapiens_hsa00230 | 0.49344534 |
92 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48148895 |
93 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.48023415 |
94 | Parkinsons disease_Homo sapiens_hsa05012 | 0.47766401 |
95 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.46561191 |
96 | Phagosome_Homo sapiens_hsa04145 | 0.46208640 |
97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.46189287 |
98 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.45710617 |
99 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.44597369 |
100 | Basal transcription factors_Homo sapiens_hsa03022 | 0.44546579 |
101 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.41593136 |
102 | Thyroid cancer_Homo sapiens_hsa05216 | 0.40272173 |
103 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.39337300 |
104 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.37083653 |
105 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.35792195 |
106 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.35440261 |
107 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.34983650 |
108 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.31682165 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.31565384 |
110 | Colorectal cancer_Homo sapiens_hsa05210 | 0.30854300 |
111 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.28628029 |
112 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.28620904 |
113 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.22360965 |
114 | Phototransduction_Homo sapiens_hsa04744 | 0.22074864 |
115 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.21543918 |
116 | Peroxisome_Homo sapiens_hsa04146 | 0.20876930 |
117 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.20350874 |
118 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.19769440 |
119 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.18778353 |
120 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.17642166 |
121 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.16605637 |
122 | Olfactory transduction_Homo sapiens_hsa04740 | 0.16377737 |
123 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.16311458 |
124 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.16285396 |
125 | Alzheimers disease_Homo sapiens_hsa05010 | 0.14973387 |
126 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.14615925 |
127 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.14299213 |
128 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.09328701 |
129 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.06908353 |
130 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.04436417 |