GMNC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ventricular system development (GO:0021591)8.82906596
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.63205174
3epithelial cilium movement (GO:0003351)7.99195521
4motile cilium assembly (GO:0044458)7.93591069
5axoneme assembly (GO:0035082)7.26642311
6C21-steroid hormone biosynthetic process (GO:0006700)7.20220550
7progesterone metabolic process (GO:0042448)6.90019179
8intraciliary transport (GO:0042073)6.47992897
9left/right axis specification (GO:0070986)6.25384272
10GTP biosynthetic process (GO:0006183)6.16151658
11nucleoside diphosphate phosphorylation (GO:0006165)6.02233568
12regulation of acrosome reaction (GO:0060046)5.72452355
13UTP biosynthetic process (GO:0006228)5.52246756
14cilium organization (GO:0044782)5.29130732
15erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.19987749
16L-phenylalanine catabolic process (GO:0006559)5.19987749
17UTP metabolic process (GO:0046051)5.12579319
18cilium assembly (GO:0042384)5.05110131
19establishment of nucleus localization (GO:0040023)4.99474776
20left/right pattern formation (GO:0060972)4.92666664
21microtubule bundle formation (GO:0001578)4.89945751
22cilium morphogenesis (GO:0060271)4.87208325
23regulation of pigment cell differentiation (GO:0050932)4.84501675
24prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060524.84445605
25centriole replication (GO:0007099)4.74443769
26negative regulation of DNA repair (GO:0045738)4.61843677
27prostate gland growth (GO:0060736)4.42434745
28microtubule severing (GO:0051013)4.42162112
29erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.38013427
30L-phenylalanine metabolic process (GO:0006558)4.38013427
31aromatic amino acid family catabolic process (GO:0009074)4.36482823
32embryonic retina morphogenesis in camera-type eye (GO:0060059)4.31048054
33phenylpropanoid metabolic process (GO:0009698)4.29339814
34nonmotile primary cilium assembly (GO:0035058)4.15164317
35C21-steroid hormone metabolic process (GO:0008207)4.14798559
36cellular component assembly involved in morphogenesis (GO:0010927)4.03917419
37lung lobe morphogenesis (GO:0060463)3.97829464
38microtubule-based movement (GO:0007018)3.91515282
39exogenous drug catabolic process (GO:0042738)3.80000098
40guanosine-containing compound biosynthetic process (GO:1901070)3.75799046
41xenobiotic catabolic process (GO:0042178)3.74497533
42CTP metabolic process (GO:0046036)3.72251884
43CTP biosynthetic process (GO:0006241)3.72251884
44daunorubicin metabolic process (GO:0044597)3.68207301
45polyketide metabolic process (GO:0030638)3.68207301
46doxorubicin metabolic process (GO:0044598)3.68207301
47nucleotide phosphorylation (GO:0046939)3.62883075
48indole-containing compound catabolic process (GO:0042436)3.62256222
49indolalkylamine catabolic process (GO:0046218)3.62256222
50tryptophan catabolic process (GO:0006569)3.62256222
51cranial suture morphogenesis (GO:0060363)3.60478851
52dorsal/ventral axis specification (GO:0009950)3.59086243
53protein localization to cilium (GO:0061512)3.56811801
54sequestering of actin monomers (GO:0042989)3.55188446
55omega-hydroxylase P450 pathway (GO:0097267)3.54620243
56cell projection assembly (GO:0030031)3.42912699
57nucleus localization (GO:0051647)3.42619389
58pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.41648273
59aminoglycoside antibiotic metabolic process (GO:0030647)3.37873125
60ADP metabolic process (GO:0046031)3.36861871
61benzene-containing compound metabolic process (GO:0042537)3.35270912
62photoreceptor cell differentiation (GO:0046530)3.31241186
63eye photoreceptor cell differentiation (GO:0001754)3.31241186
64cellular ketone body metabolic process (GO:0046950)3.30476041
65drug catabolic process (GO:0042737)3.26584580
66heme transport (GO:0015886)3.25682532
67pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.25060101
68keratinocyte development (GO:0003334)3.24686263
69cerebellar granule cell differentiation (GO:0021707)3.24610669
70positive regulation of protein depolymerization (GO:1901881)3.23088790
71regulation of protein polyubiquitination (GO:1902914)3.17313334
72amyloid precursor protein catabolic process (GO:0042987)3.17287422
73lateral ventricle development (GO:0021670)3.16298723
74axon ensheathment in central nervous system (GO:0032291)3.14998797
75central nervous system myelination (GO:0022010)3.14998797
76oxygen transport (GO:0015671)3.13499903
77vocalization behavior (GO:0071625)3.13459943
78epoxygenase P450 pathway (GO:0019373)3.12808036
79regulation of autophagic vacuole assembly (GO:2000785)3.12324303
80determination of bilateral symmetry (GO:0009855)3.12041208
81cardiovascular system development (GO:0072358)3.11421532
82tyrosine metabolic process (GO:0006570)3.10777755
83specification of symmetry (GO:0009799)3.07304681
84behavioral response to nicotine (GO:0035095)3.07088168
85lung vasculature development (GO:0060426)3.05644570
86ketone biosynthetic process (GO:0042181)3.04654811
87neurotransmitter-gated ion channel clustering (GO:0072578)3.03030233
88iron coordination entity transport (GO:1901678)3.00115988
89positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.91895038
90craniofacial suture morphogenesis (GO:0097094)2.89966206
91ketone body metabolic process (GO:1902224)2.89487906
92nonribosomal peptide biosynthetic process (GO:0019184)2.88405533
93detection of calcium ion (GO:0005513)2.88379730
94lateral sprouting from an epithelium (GO:0060601)2.84397564
95retinal metabolic process (GO:0042574)2.83591107
96establishment of mitochondrion localization (GO:0051654)2.81992297
97neuron remodeling (GO:0016322)2.81645610
98mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.79791511
99mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.78969596
100regulation of cilium movement (GO:0003352)2.78815518
101branching involved in prostate gland morphogenesis (GO:0060442)2.78809496
102regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.78325861
103inner ear receptor stereocilium organization (GO:0060122)2.77419551
104nerve growth factor signaling pathway (GO:0038180)2.77302946
105base-excision repair, AP site formation (GO:0006285)2.77205716
106regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.76940755
107positive regulation of megakaryocyte differentiation (GO:0045654)2.76867510
108smoothened signaling pathway (GO:0007224)2.76285823
109peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.76160261
110positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.74957314
111photoreceptor cell maintenance (GO:0045494)2.73724258
112sperm motility (GO:0030317)2.66953208
113regulation of vacuole organization (GO:0044088)2.66718456
114energy coupled proton transport, down electrochemical gradient (GO:0015985)2.65166979
115ATP synthesis coupled proton transport (GO:0015986)2.65166979
116retina layer formation (GO:0010842)2.64413269
117tryptophan metabolic process (GO:0006568)2.64329630
118positive regulation of developmental pigmentation (GO:0048087)2.62965160
119locomotory exploration behavior (GO:0035641)2.62455956
120aromatic amino acid family metabolic process (GO:0009072)2.61376280
121neuron cell-cell adhesion (GO:0007158)2.60707578
122regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.59775523
123proline transport (GO:0015824)2.58954555
124gas transport (GO:0015669)2.58539384
125glomerular epithelial cell development (GO:0072310)2.58334944
126negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.58131471
127positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-2.56592546
128pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.56204744
129dentate gyrus development (GO:0021542)2.56197525
130regulation of DNA endoreduplication (GO:0032875)2.54752736
131regulation of glutamate receptor signaling pathway (GO:1900449)2.53598302
132neural tube formation (GO:0001841)2.53377549
133nucleoside diphosphate metabolic process (GO:0009132)2.52382001
134pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.51071714
135amine catabolic process (GO:0009310)2.49901713
136cellular biogenic amine catabolic process (GO:0042402)2.49901713
137response to pheromone (GO:0019236)2.49840030
138mitochondrion transport along microtubule (GO:0047497)2.49618086
139establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.49618086
140neuronal action potential propagation (GO:0019227)2.48883578
141positive regulation of filopodium assembly (GO:0051491)2.48397510
142negative regulation of astrocyte differentiation (GO:0048712)2.47365182
143bile acid biosynthetic process (GO:0006699)2.46903273
144regulation of phospholipid biosynthetic process (GO:0071071)2.46499723
145pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.45508564
146otic vesicle formation (GO:0030916)2.44219243
147cellular glucuronidation (GO:0052695)2.42395151
148receptor clustering (GO:0043113)2.41979663
149establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.41828215
150centriole assembly (GO:0098534)2.40939462
151substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.40797217
152substrate-independent telencephalic tangential migration (GO:0021826)2.40797217
153ionotropic glutamate receptor signaling pathway (GO:0035235)2.39863320
154synaptic vesicle maturation (GO:0016188)2.39491602
155electron transport chain (GO:0022900)2.38001883
156pyrimidine ribonucleotide metabolic process (GO:0009218)2.37781847
157fibrinolysis (GO:0042730)2.37760205
158postsynaptic membrane organization (GO:0001941)2.37646471
159serotonin receptor signaling pathway (GO:0007210)2.37406238
160positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.35531581
161regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.35218330
162negative regulation of inclusion body assembly (GO:0090084)2.34550211
163purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.33940842
164peptide hormone processing (GO:0016486)2.33489125
165positive regulation of vesicle fusion (GO:0031340)2.31177926
166regulation of beta-amyloid formation (GO:1902003)2.30814025
167positive regulation of protein complex disassembly (GO:0043243)2.30515057
168regulation of bile acid biosynthetic process (GO:0070857)2.30330567
169mitotic cell cycle arrest (GO:0071850)2.30177500
170protein polyglutamylation (GO:0018095)2.29294296
171microtubule-based transport (GO:0010970)2.29219724
172glutamate receptor signaling pathway (GO:0007215)2.28689533
173determination of left/right symmetry (GO:0007368)2.28352467
174axonemal dynein complex assembly (GO:0070286)13.3536117
175cilium movement (GO:0003341)12.0652858
176cilium or flagellum-dependent cell motility (GO:0001539)10.5101035

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.21318083
2AR_21572438_ChIP-Seq_LNCaP_Human4.03793563
3TAF15_26573619_Chip-Seq_HEK293_Human3.40855535
4SMAD_19615063_ChIP-ChIP_OVARY_Human2.79441021
5GBX2_23144817_ChIP-Seq_PC3_Human2.79139425
6EZH2_22144423_ChIP-Seq_EOC_Human2.69862719
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.61299567
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.43721375
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.28788160
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.28302129
11IGF1R_20145208_ChIP-Seq_DFB_Human2.11431801
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.09808844
13EWS_26573619_Chip-Seq_HEK293_Human2.08515935
14EZH2_27294783_Chip-Seq_ESCs_Mouse2.07374041
15DROSHA_22980978_ChIP-Seq_HELA_Human2.06843220
16JARID2_20064375_ChIP-Seq_MESCs_Mouse2.04690077
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.02815459
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.00682391
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.98418534
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.97860233
21EZH2_18974828_ChIP-Seq_MESCs_Mouse1.95683037
22RNF2_18974828_ChIP-Seq_MESCs_Mouse1.95683037
23PIAS1_25552417_ChIP-Seq_VCAP_Human1.92663616
24CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.82203818
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.82038682
26SMAD4_21799915_ChIP-Seq_A2780_Human1.80404186
27CDX2_19796622_ChIP-Seq_MESCs_Mouse1.80100730
28MTF2_20144788_ChIP-Seq_MESCs_Mouse1.76993625
29SUZ12_27294783_Chip-Seq_ESCs_Mouse1.75330819
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74339686
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.73940492
32EZH2_27304074_Chip-Seq_ESCs_Mouse1.73305646
33JARID2_20075857_ChIP-Seq_MESCs_Mouse1.72138048
34EED_16625203_ChIP-ChIP_MESCs_Mouse1.66637301
35FOXM1_26456572_ChIP-Seq_MCF-7_Human1.62433256
36NR3C1_21868756_ChIP-Seq_MCF10A_Human1.60013439
37AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.57971298
38STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.57954797
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.55528161
40TP63_19390658_ChIP-ChIP_HaCaT_Human1.50733404
41ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.50392385
42RNF2_27304074_Chip-Seq_ESCs_Mouse1.47440230
43TP53_16413492_ChIP-PET_HCT116_Human1.47298125
44CTBP2_25329375_ChIP-Seq_LNCAP_Human1.46969053
45P300_19829295_ChIP-Seq_ESCs_Human1.46838819
46STAT3_23295773_ChIP-Seq_U87_Human1.42514955
47ARNT_22903824_ChIP-Seq_MCF-7_Human1.40583725
48REST_21632747_ChIP-Seq_MESCs_Mouse1.39171417
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38946020
50GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38794374
51PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.38306145
52TCF4_22108803_ChIP-Seq_LS180_Human1.38024870
53TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37987051
54TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.34920765
55SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34852616
56ERG_21242973_ChIP-ChIP_JURKAT_Human1.34833619
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.33706098
58ER_23166858_ChIP-Seq_MCF-7_Human1.33205999
59RXR_22108803_ChIP-Seq_LS180_Human1.30454311
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29610565
61FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.29427372
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.28972319
63LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28525553
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.28431218
65LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.26545387
66PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25298405
67CDX2_22108803_ChIP-Seq_LS180_Human1.24992631
68OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24885408
69CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22185961
70RUNX2_22187159_ChIP-Seq_PCA_Human1.21023990
71POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19900979
72CBX2_27304074_Chip-Seq_ESCs_Mouse1.19281622
73NANOG_19829295_ChIP-Seq_ESCs_Human1.18898845
74SOX2_19829295_ChIP-Seq_ESCs_Human1.18898845
75NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.18846076
76ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18322819
77PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18266363
78FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.18239859
79CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.17903571
80RNF2_27304074_Chip-Seq_NSC_Mouse1.17606749
81NANOG_18555785_Chip-Seq_ESCs_Mouse1.17584927
82BCAT_22108803_ChIP-Seq_LS180_Human1.17542062
83RING1B_27294783_Chip-Seq_ESCs_Mouse1.17252409
84PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16615382
85TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.16569897
86TBL1_22424771_ChIP-Seq_293T_Human1.16563392
87FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.16142678
88E2F1_18555785_Chip-Seq_ESCs_Mouse1.15801458
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15627291
90VDR_22108803_ChIP-Seq_LS180_Human1.15401737
91FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.14590989
92WDR5_24793694_ChIP-Seq_LNCAP_Human1.13698996
93NRF2_20460467_ChIP-Seq_MEFs_Mouse1.12957858
94NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.12957858
95KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12832236
96ZNF274_21170338_ChIP-Seq_K562_Hela1.12253065
97E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.11538234
98EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.11210881
99TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10776634
100POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10776634
101MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10763469
102AHR_22903824_ChIP-Seq_MCF-7_Human1.10753771
103TRIM28_21343339_ChIP-Seq_HEK293_Human1.10237152
104ERG_20517297_ChIP-Seq_VCAP_Human1.09435133
105NR3C1_23031785_ChIP-Seq_PC12_Mouse1.08531349
106GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07292502
107REST_18959480_ChIP-ChIP_MESCs_Mouse1.07102008
108RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06821487
109HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.06286065
110STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05998754
111TP53_18474530_ChIP-ChIP_U2OS_Human1.05929355
112FUS_26573619_Chip-Seq_HEK293_Human1.05072061
113SOX2_21211035_ChIP-Seq_LN229_Gbm1.04995792
114AR_25329375_ChIP-Seq_VCAP_Human1.04659122
115AR_19668381_ChIP-Seq_PC3_Human1.04653432
116RARB_27405468_Chip-Seq_BRAIN_Mouse1.04385783
117P53_22387025_ChIP-Seq_ESCs_Mouse1.03720669
118CBP_20019798_ChIP-Seq_JUKART_Human1.03585495
119IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.03585495
120CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.02564249
121PHF8_20622853_ChIP-Seq_HELA_Human1.02046730
122BMI1_23680149_ChIP-Seq_NPCS_Mouse1.01204221
123FOXA1_25552417_ChIP-Seq_VCAP_Human1.00921762
124EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99596593
125AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.99571967
126PRDM14_20953172_ChIP-Seq_ESCs_Human0.99465257
127MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.98884189
128TAL1_26923725_Chip-Seq_HPCs_Mouse0.98551795
129CMYC_18555785_Chip-Seq_ESCs_Mouse0.97523653
130TCF4_23295773_ChIP-Seq_U87_Human0.97044714
131MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96959135
132SMAD4_21741376_ChIP-Seq_EPCs_Human0.96106417
133SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95951025
134WT1_25993318_ChIP-Seq_PODOCYTE_Human0.95559919
135ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.92964874
136EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.92577583

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008004_abnormal_stomach_pH7.02952370
2MP0003136_yellow_coat_color6.51620678
3MP0000566_synostosis5.46213986
4MP0010030_abnormal_orbit_morphology4.26804739
5MP0004859_abnormal_synaptic_plasticity4.13303813
6MP0005623_abnormal_meninges_morphology3.51120411
7MP0002653_abnormal_ependyma_morphology3.19557248
8MP0003195_calcinosis2.91219713
9MP0003880_abnormal_central_pattern2.82568270
10MP0004133_heterotaxia2.77193516
11MP0005647_abnormal_sex_gland2.70358187
12MP0002928_abnormal_bile_duct2.67710154
13MP0004270_analgesia2.58859188
14MP0001984_abnormal_olfaction2.53098477
15MP0004043_abnormal_pH_regulation2.41655019
16MP0010386_abnormal_urinary_bladder2.31177804
17MP0009046_muscle_twitch2.26001314
18MP0000537_abnormal_urethra_morphology2.24450760
19MP0003635_abnormal_synaptic_transmissio2.24206012
20MP0004381_abnormal_hair_follicle2.23417704
21MP0002160_abnormal_reproductive_system2.10905525
22MP0009780_abnormal_chondrocyte_physiolo2.09922051
23MP0009745_abnormal_behavioral_response2.06141357
24MP0002139_abnormal_hepatobiliary_system1.98146239
25MP0002064_seizures1.94306534
26MP0005085_abnormal_gallbladder_physiolo1.90131125
27MP0001501_abnormal_sleep_pattern1.89000112
28MP0008961_abnormal_basal_metabolism1.84081471
29MP0004019_abnormal_vitamin_homeostasis1.82322010
30MP0008875_abnormal_xenobiotic_pharmacok1.80767093
31MP0009384_cardiac_valve_regurgitation1.80344128
32MP0003879_abnormal_hair_cell1.79885667
33MP0006072_abnormal_retinal_apoptosis1.75293351
34MP0000778_abnormal_nervous_system1.73756682
35MP0002063_abnormal_learning/memory/cond1.73350172
36MP0000462_abnormal_digestive_system1.72083024
37MP0002572_abnormal_emotion/affect_behav1.71227169
38MP0001968_abnormal_touch/_nociception1.68310168
39MP0003950_abnormal_plasma_membrane1.68234348
40MP0002734_abnormal_mechanical_nocicepti1.65055166
41MP0003646_muscle_fatigue1.63960557
42MP0001502_abnormal_circadian_rhythm1.62490064
43MP0000534_abnormal_ureter_morphology1.61438281
44MP0002272_abnormal_nervous_system1.60386541
45MP0001873_stomach_inflammation1.59547371
46MP0000372_irregular_coat_pigmentation1.58833788
47MP0003718_maternal_effect1.57760896
48MP0001188_hyperpigmentation1.53962623
49MP0002736_abnormal_nociception_after1.53110030
50MP0000579_abnormal_nail_morphology1.51129875
51MP0002295_abnormal_pulmonary_circulatio1.50630831
52MP0001299_abnormal_eye_distance/1.49209933
53MP0001486_abnormal_startle_reflex1.48763230
54MP0005365_abnormal_bile_salt1.44477938
55MP0001440_abnormal_grooming_behavior1.42856466
56MP0002249_abnormal_larynx_morphology1.41882784
57MP0001177_atelectasis1.41419221
58MP0008995_early_reproductive_senescence1.41253893
59MP0005646_abnormal_pituitary_gland1.38948730
60MP0003122_maternal_imprinting1.38049672
61MP0006292_abnormal_olfactory_placode1.37692732
62MP0001666_abnormal_nutrient_absorption1.37533462
63MP0003690_abnormal_glial_cell1.37001168
64MP0005409_darkened_coat_color1.35191458
65MP0003011_delayed_dark_adaptation1.34305816
66MP0000026_abnormal_inner_ear1.33175720
67MP0009379_abnormal_foot_pigmentation1.32998055
68MP0002638_abnormal_pupillary_reflex1.29277816
69MP0003121_genomic_imprinting1.24635750
70MP0001958_emphysema1.24200543
71MP0005395_other_phenotype1.23052618
72MP0001485_abnormal_pinna_reflex1.22356955
73MP0002938_white_spotting1.20726914
74MP0002557_abnormal_social/conspecific_i1.19957252
75MP0002233_abnormal_nose_morphology1.14366602
76MP0008569_lethality_at_weaning1.11189654
77MP0003634_abnormal_glial_cell1.10845266
78MP0005253_abnormal_eye_physiology1.09393269
79MP0002184_abnormal_innervation1.08099640
80MP0000613_abnormal_salivary_gland1.08003852
81MP0003045_fibrosis1.07626507
82MP0002067_abnormal_sensory_capabilities1.07446962
83MP0005389_reproductive_system_phenotype1.06449477
84MP0010368_abnormal_lymphatic_system1.06382714
85MP0003943_abnormal_hepatobiliary_system1.06318541
86MP0003959_abnormal_lean_body1.06066797
87MP0001963_abnormal_hearing_physiology1.05857660
88MP0002133_abnormal_respiratory_system1.04951312
89MP0005388_respiratory_system_phenotype1.04951312
90MP0002735_abnormal_chemical_nociception1.03250485
91MP0003942_abnormal_urinary_system1.02759876
92MP0004811_abnormal_neuron_physiology1.02609135
93MP0000955_abnormal_spinal_cord1.00704830
94MP0008789_abnormal_olfactory_epithelium0.99025931
95MP0004885_abnormal_endolymph0.97321104
96MP0001542_abnormal_bone_strength0.96882687
97MP0004858_abnormal_nervous_system0.96811376
98MP0005248_abnormal_Harderian_gland0.96175706
99MP0002882_abnormal_neuron_morphology0.95918741
100MP0005377_hearing/vestibular/ear_phenot0.95782976
101MP0003878_abnormal_ear_physiology0.95782976
102MP0005408_hypopigmentation0.95570409
103MP0005171_absent_coat_pigmentation0.95482220
104MP0002282_abnormal_trachea_morphology0.95326778
105MP0000516_abnormal_urinary_system0.94406986
106MP0005367_renal/urinary_system_phenotyp0.94406986
107MP0005332_abnormal_amino_acid0.91573969
108MP0002876_abnormal_thyroid_physiology0.90553997
109MP0003633_abnormal_nervous_system0.88976746
110MP0001905_abnormal_dopamine_level0.87910274
111MP0000049_abnormal_middle_ear0.87440371
112MP0001851_eye_inflammation0.87040599
113MP0000003_abnormal_adipose_tissue0.85701576
114MP0001756_abnormal_urination0.85450837
115MP0004742_abnormal_vestibular_system0.85157396
116MP0000470_abnormal_stomach_morphology0.83776584
117MP0002066_abnormal_motor_capabilities/c0.83727410
118MP0005220_abnormal_exocrine_pancreas0.83217181
119MP0004145_abnormal_muscle_electrophysio0.81903308
120MP0002909_abnormal_adrenal_gland0.81637406
121MP0002152_abnormal_brain_morphology0.80195470
122MP0008877_abnormal_DNA_methylation0.79834129
123MP0003329_amyloid_beta_deposits0.79417739
124MP0009053_abnormal_anal_canal0.78280983
125MP0004147_increased_porphyrin_level0.77088514
126MP0003868_abnormal_feces_composition0.76681911
127MP0004142_abnormal_muscle_tone0.76329572
128MP0005075_abnormal_melanosome_morpholog0.75486005
129MP0003631_nervous_system_phenotype0.75314509
130MP0008872_abnormal_physiological_respon0.73943864
131MP0003938_abnormal_ear_development0.73509699
132MP0002108_abnormal_muscle_morphology0.73310357
133MP0000920_abnormal_myelination0.72515128
134MP0005551_abnormal_eye_electrophysiolog0.71911179
135MP0006276_abnormal_autonomic_nervous0.71879532
136MP0005423_abnormal_somatic_nervous0.70873874
137MP0004484_altered_response_of0.70776579
138MP0000538_abnormal_urinary_bladder0.70763168
139MP0002168_other_aberrant_phenotype0.70739866
140MP0001970_abnormal_pain_threshold0.70518568
141MP0001663_abnormal_digestive_system0.69879367
142MP0003283_abnormal_digestive_organ0.69133276
143MP0005595_abnormal_vascular_smooth0.68176866
144MP0004924_abnormal_behavior0.67512211
145MP0005386_behavior/neurological_phenoty0.67512211
146MP0000631_abnormal_neuroendocrine_gland0.67403962
147MP0003937_abnormal_limbs/digits/tail_de0.67282519
148MP0003638_abnormal_response/metabolism_0.67031715
149MP0003075_altered_response_to0.66915105
150MP0002234_abnormal_pharynx_morphology0.65562213
151MP0002752_abnormal_somatic_nervous0.65277328
152MP0003632_abnormal_nervous_system0.60343668
153MP0005381_digestive/alimentary_phenotyp0.58966850
154MP0005670_abnormal_white_adipose0.57990724
155MP0001943_abnormal_respiration0.57583140
156MP0008874_decreased_physiological_sensi0.57444615
157MP0004782_abnormal_surfactant_physiolog0.56615952
158MP0001346_abnormal_lacrimal_gland0.55492657
159MP0005187_abnormal_penis_morphology0.55153798
160MP0000747_muscle_weakness0.54438737

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)8.77331234
2Rhinitis (HP:0012384)8.27849470
3Abnormal respiratory epithelium morphology (HP:0012253)8.07870802
4Abnormal respiratory motile cilium morphology (HP:0005938)8.07870802
5Dynein arm defect of respiratory motile cilia (HP:0012255)6.52222975
6Absent/shortened dynein arms (HP:0200106)6.52222975
7Male infertility (HP:0003251)6.02754652
8Bronchiectasis (HP:0002110)4.71250199
9Degeneration of the lateral corticospinal tracts (HP:0002314)4.70089814
10Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.70089814
11Occipital encephalocele (HP:0002085)4.57395732
12Nasal polyposis (HP:0100582)4.40185667
13True hermaphroditism (HP:0010459)4.14291930
14Chronic bronchitis (HP:0004469)4.12888147
15Insidious onset (HP:0003587)3.92501478
16Termporal pattern (HP:0011008)3.92501478
17Bile duct proliferation (HP:0001408)3.84758196
18Abnormal biliary tract physiology (HP:0012439)3.84758196
19Abnormality of the corticospinal tract (HP:0002492)3.79139324
20Pancreatic fibrosis (HP:0100732)3.72460708
21Genetic anticipation (HP:0003743)3.69611120
22Infertility (HP:0000789)3.64591260
23Abnormality of the nasal mucosa (HP:0000433)3.59231482
24Steatorrhea (HP:0002570)3.56762079
25Chronic sinusitis (HP:0011109)3.49133335
26Abnormality of dentin (HP:0010299)3.43200471
27Chronic otitis media (HP:0000389)3.41249449
28Back pain (HP:0003418)3.41234199
29Asplenia (HP:0001746)3.36994081
30Gait imbalance (HP:0002141)3.34197022
31Supernumerary spleens (HP:0009799)3.29569498
32Medial flaring of the eyebrow (HP:0010747)3.29176728
33Congenital primary aphakia (HP:0007707)3.22566763
34Aplasia/Hypoplasia of the spleen (HP:0010451)3.11121304
35Tubulointerstitial nephritis (HP:0001970)3.10015143
36Fat malabsorption (HP:0002630)3.00842727
37Abnormality of the fetal cardiovascular system (HP:0010948)2.92607953
38Abnormal umbilical cord blood vessels (HP:0011403)2.92607953
39Single umbilical artery (HP:0001195)2.92607953
40Male pseudohermaphroditism (HP:0000037)2.92385922
41Nephrogenic diabetes insipidus (HP:0009806)2.90119573
42Cystic liver disease (HP:0006706)2.89332566
43Pancreatic cysts (HP:0001737)2.80730351
44Taurodontia (HP:0000679)2.72428870
45Abnormality of permanent molar morphology (HP:0011071)2.72428870
46Abnormality of the dental root (HP:0006486)2.72428870
47Abnormality of the renal medulla (HP:0100957)2.66326524
48Short nail (HP:0001799)2.65975316
49Abnormality of the labia majora (HP:0012881)2.64137023
50Popliteal pterygium (HP:0009756)2.61719054
51Abnormality of molar morphology (HP:0011070)2.60815258
52Abnormality of molar (HP:0011077)2.60815258
53Hypoplastic labia majora (HP:0000059)2.59205338
54Tubular atrophy (HP:0000092)2.56472747
55Impaired vibration sensation in the lower limbs (HP:0002166)2.53281273
56Focal motor seizures (HP:0011153)2.50944726
57Oral leukoplakia (HP:0002745)2.48459790
58Abnormality of the dental pulp (HP:0006479)2.47216511
59Broad distal phalanx of finger (HP:0009836)2.42399217
60Poor coordination (HP:0002370)2.42234764
61Exocrine pancreatic insufficiency (HP:0001738)2.41342255
62Urinary bladder sphincter dysfunction (HP:0002839)2.39756773
63Postaxial foot polydactyly (HP:0001830)2.34259884
64Aplasia/Hypoplasia of the tongue (HP:0010295)2.33986743
65Vascular calcification (HP:0004934)2.32695137
66Natal tooth (HP:0000695)2.31431958
67Vaginal atresia (HP:0000148)2.29847114
68Hemiplegia (HP:0002301)2.26080780
69Genital tract atresia (HP:0001827)2.23622458
70Urinary urgency (HP:0000012)2.23537825
71Congenital hepatic fibrosis (HP:0002612)2.21479441
72Breech presentation (HP:0001623)2.19759641
73Recurrent sinusitis (HP:0011108)2.17079000
74Bronchitis (HP:0012387)2.16244670
75Agitation (HP:0000713)2.14614501
76Chronic hepatic failure (HP:0100626)2.13040062
77Abnormality of the labia minora (HP:0012880)2.12824585
78Prolonged partial thromboplastin time (HP:0003645)2.08869726
79Cardiovascular calcification (HP:0011915)2.08696074
80Disinhibition (HP:0000734)2.06768993
81Hypotelorism (HP:0000601)2.06765010
82Anencephaly (HP:0002323)2.04303869
83Hypobetalipoproteinemia (HP:0003563)2.01110617
84Abnormal ciliary motility (HP:0012262)10.7470331
85Abnormal respiratory motile cilium physiology (HP:0012261)10.2982073
86Increased hepatocellular lipid droplets (HP:0006565)1.99928081
87Labial hypoplasia (HP:0000066)1.99680097
88Lipid accumulation in hepatocytes (HP:0006561)1.97505734
89Atelectasis (HP:0100750)1.94839857
90Median cleft lip (HP:0000161)1.90930985
91Morphological abnormality of the pyramidal tract (HP:0002062)1.89431522
92Furrowed tongue (HP:0000221)1.88672156
93Narrow forehead (HP:0000341)1.88290523
94Broad metatarsal (HP:0001783)1.86145135
95Nephronophthisis (HP:0000090)1.85643766
96Adrenal hypoplasia (HP:0000835)1.84811518
97Specific learning disability (HP:0001328)1.81466413
98Buphthalmos (HP:0000557)1.78181529
99Preaxial hand polydactyly (HP:0001177)1.76920554
100Hypoplastic female external genitalia (HP:0012815)1.76261295
101Rimmed vacuoles (HP:0003805)1.75827991
102Aplasia/Hypoplasia of the lens (HP:0008063)1.73691865
103Abnormality of the middle phalanges of the toes (HP:0010183)1.72965891
104Recurrent otitis media (HP:0000403)1.72961310
105Oculomotor apraxia (HP:0000657)1.71525587
106Coronal craniosynostosis (HP:0004440)1.71110255
107Abnormality of midbrain morphology (HP:0002418)1.70834354
108Molar tooth sign on MRI (HP:0002419)1.70834354
109Hyperactive renin-angiotensin system (HP:0000841)1.70786702
110Abnormality of aromatic amino acid family metabolism (HP:0004338)1.70347047
111Turricephaly (HP:0000262)1.69842421
112Abnormality of the umbilical cord (HP:0010881)1.69840429
113Abnormal drinking behavior (HP:0030082)1.68370768
114Polydipsia (HP:0001959)1.68370768
115Abnormality of the lower motor neuron (HP:0002366)1.67422145
116Abnormality of the phalanges of the 2nd finger (HP:0009541)1.67383064
117Exercise-induced myalgia (HP:0003738)1.67361382
118Sclerocornea (HP:0000647)1.65625798
119Bronchomalacia (HP:0002780)1.65228510
120Tubulointerstitial fibrosis (HP:0005576)1.64770573
121Tubulointerstitial abnormality (HP:0001969)1.62490287
122Esophageal atresia (HP:0002032)1.62219829
123Broad foot (HP:0001769)1.61686141
124Abnormality of the renal cortex (HP:0011035)1.58056795
125Hyperglycinuria (HP:0003108)1.56086441
126Hyperventilation (HP:0002883)1.56085673
127Inappropriate behavior (HP:0000719)1.56048021
128Renal Fanconi syndrome (HP:0001994)1.52885552
129Respiratory distress (HP:0002098)1.51368713
130Gaze-evoked nystagmus (HP:0000640)1.50888590
131Abnormal rod and cone electroretinograms (HP:0008323)1.50576529
132Hyperinsulinemic hypoglycemia (HP:0000825)1.48823482
133Postaxial hand polydactyly (HP:0001162)1.48538732
134Stomach cancer (HP:0012126)1.47535662
135Decreased muscle mass (HP:0003199)1.47057341
136Aqueductal stenosis (HP:0002410)1.46916033
137Limb dystonia (HP:0002451)1.45956313
138Myokymia (HP:0002411)1.45844372
139Omphalocele (HP:0001539)1.45459736
140Impaired vibratory sensation (HP:0002495)1.43974859
141Stage 5 chronic kidney disease (HP:0003774)1.43116409
142Spontaneous abortion (HP:0005268)1.42464504
143Peripheral hypomyelination (HP:0007182)1.38519048

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK156.28146392
2FGFR24.92283879
3MAP3K64.72713916
4GRK13.60048509
5EEF2K3.38617706
6NTRK33.29545083
7PNCK3.11560376
8FRK2.95784289
9CASK2.91644810
10ERBB32.81645432
11CDC42BPA2.54996049
12MAP2K32.53681575
13MAP2K72.46181564
14BMPR22.45275802
15MUSK2.43908494
16EPHA42.32909996
17STK242.32437297
18MAP4K22.21485005
19BMPR1B2.14279399
20TRPM72.11402434
21MAPKAPK32.09816387
22MAP3K42.03528281
23TNIK1.98136191
24PRKCG1.85325684
25MAPK131.83407741
26PTK2B1.68520027
27WNK31.66161683
28NTRK21.61472859
29MAP3K21.52994225
30MAPKAPK51.49977554
31MARK11.49055402
32MAP3K121.43237551
33MAP3K51.42104523
34BCR1.40818229
35BRD41.39684661
36MAP2K61.36202652
37MYLK1.32530633
38STK38L1.30124802
39PINK11.24457549
40EIF2AK11.22885011
41MAP2K41.18918681
42MAPK121.18737104
43MST41.15068155
44FGR1.12508198
45MINK11.11918955
46SIK11.10527861
47ARAF1.10422444
48CAMK2B1.10092436
49RPS6KA21.09767978
50PAK31.09193494
51MKNK21.07264182
52ADRBK11.06581347
53WNK41.05929472
54MAP3K31.04943627
55FGFR11.04680064
56CAMK2A1.01384064
57BRSK21.01096874
58PRKCE0.97107805
59CAMKK10.96373827
60ACVR1B0.94955790
61VRK20.92365420
62ROCK20.89824732
63RIPK40.88773449
64CDK50.88039864
65PRPF4B0.85594555
66TLK10.85381210
67INSRR0.85063405
68CDK30.83795023
69CAMK1G0.79873110
70ADRBK20.78429660
71NEK60.78383418
72PAK60.76084927
73MAPK70.75828075
74FES0.74501802
75ZAP700.74110593
76CAMKK20.70932418
77DAPK10.69970945
78SCYL20.69121732
79PLK40.68812240
80MELK0.68751725
81DYRK30.64829085
82PASK0.63543254
83STK30.63476834
84PLK20.61571553
85UHMK10.58649554
86LIMK10.56839466
87PHKG10.56669010
88PHKG20.56669010
89RPS6KB20.56405458
90PAK20.55083058
91EIF2AK30.54805400
92STK390.51588004
93RET0.51337839
94BRSK10.51031957
95DAPK20.50892201
96MAP2K10.50487656
97CAMK2G0.50441312
98GRK50.50179594
99PRKCH0.50015867
100PIM20.49900681
101WNK10.48088945
102TGFBR10.47245544
103DYRK20.47220076
104CAMK2D0.46645160
105DYRK1A0.46400776
106PTK20.46136893
107LMTK20.45483749
108RPS6KA30.45281020
109FGFR30.42483714
110LATS10.42470266
111DDR20.42174903
112PRKCZ0.42101044
113OXSR10.41870735
114CAMK10.41541105
115PRKACA0.40051341
116PRKACB0.39815513
117PRKACG0.39636716
118TSSK60.39079911
119SGK4940.39077126
120SGK2230.39077126
121PKN10.39003090
122DYRK1B0.38880396
123SRC0.38707877
124PRKG10.37868145
125WEE10.37280535
126CSK0.36735246
127DAPK30.36488040
128SGK20.36010275
129CSNK1E0.35861734
130GSK3A0.35774064
131FYN0.35303764
132CSNK1A1L0.34803176
133MAPK110.34147395
134MAP2K20.32512956
135EPHB10.32494482
136RPS6KA50.32485535
137FER0.32327540
138GRK70.32268940
139MAP3K90.31914953
140PRKAA20.31574415
141ROCK10.31527447
142PRKCB0.30879267
143NEK20.30170144
144SGK10.29518047
145PLK30.29505244
146ERBB20.29016439
147MAPK80.28954839
148CSNK1A10.28341880
149CHUK0.27501460
150AURKA0.27345033
151PRKCA0.27077829
152LATS20.26825704
153RIPK10.26771833
154KSR10.26600361
155CDK180.25811169
156EPHA20.23377163
157RPS6KB10.21138622
158RPS6KA10.20764386
159ZAK0.19533925

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.26435040
2Chemical carcinogenesis_Homo sapiens_hsa052042.81239499
3Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.76374526
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.71793819
5Nicotine addiction_Homo sapiens_hsa050332.70205031
6Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.67061580
7Ovarian steroidogenesis_Homo sapiens_hsa049132.62652100
8Circadian entrainment_Homo sapiens_hsa047132.30509706
9GnRH signaling pathway_Homo sapiens_hsa049122.23501219
10Tryptophan metabolism_Homo sapiens_hsa003802.22940928
11Retinol metabolism_Homo sapiens_hsa008302.19809539
12Steroid hormone biosynthesis_Homo sapiens_hsa001402.18332979
13Collecting duct acid secretion_Homo sapiens_hsa049662.17957703
14Caffeine metabolism_Homo sapiens_hsa002322.17611209
15Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.12395124
16Olfactory transduction_Homo sapiens_hsa047402.10969130
17Synaptic vesicle cycle_Homo sapiens_hsa047212.00755958
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.98183717
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.96873569
20GABAergic synapse_Homo sapiens_hsa047271.93290521
21Tyrosine metabolism_Homo sapiens_hsa003501.91924107
22Complement and coagulation cascades_Homo sapiens_hsa046101.89910467
23Glutamatergic synapse_Homo sapiens_hsa047241.89110643
24Gastric acid secretion_Homo sapiens_hsa049711.87252911
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.83381646
26Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.81412674
27Parkinsons disease_Homo sapiens_hsa050121.78215799
28Calcium signaling pathway_Homo sapiens_hsa040201.76002575
29Salivary secretion_Homo sapiens_hsa049701.72592647
30Folate biosynthesis_Homo sapiens_hsa007901.71738055
31Amphetamine addiction_Homo sapiens_hsa050311.71649607
32Vitamin B6 metabolism_Homo sapiens_hsa007501.70495850
33Long-term potentiation_Homo sapiens_hsa047201.67336712
34Phenylalanine metabolism_Homo sapiens_hsa003601.56156608
35Insulin secretion_Homo sapiens_hsa049111.53277582
36Pentose and glucuronate interconversions_Homo sapiens_hsa000401.51318518
37Huntingtons disease_Homo sapiens_hsa050161.46074139
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.44893287
39Morphine addiction_Homo sapiens_hsa050321.42515874
40Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.33592801
41Oxytocin signaling pathway_Homo sapiens_hsa049211.32895939
42Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.32000588
43Axon guidance_Homo sapiens_hsa043601.31877853
44Renin secretion_Homo sapiens_hsa049241.29679548
45Long-term depression_Homo sapiens_hsa047301.29284982
46Dopaminergic synapse_Homo sapiens_hsa047281.27031980
47Linoleic acid metabolism_Homo sapiens_hsa005911.25939894
48Circadian rhythm_Homo sapiens_hsa047101.25282175
49Selenocompound metabolism_Homo sapiens_hsa004501.22622995
50Butanoate metabolism_Homo sapiens_hsa006501.21948246
51Aldosterone synthesis and secretion_Homo sapiens_hsa049251.17102480
52Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.16163414
53Cholinergic synapse_Homo sapiens_hsa047251.14220727
54Cocaine addiction_Homo sapiens_hsa050301.14036867
55Vibrio cholerae infection_Homo sapiens_hsa051101.12557235
56Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.12412711
57cAMP signaling pathway_Homo sapiens_hsa040241.09491395
58ABC transporters_Homo sapiens_hsa020101.09244051
59Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.07635721
60Prolactin signaling pathway_Homo sapiens_hsa049171.06362813
61Melanogenesis_Homo sapiens_hsa049161.05935179
62Phototransduction_Homo sapiens_hsa047441.04354608
63Serotonergic synapse_Homo sapiens_hsa047261.03987176
64Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.03763278
65Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.99762414
66Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.98960232
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.98390502
68Protein export_Homo sapiens_hsa030600.97408209
69Cardiac muscle contraction_Homo sapiens_hsa042600.95577472
70Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.94648726
71Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91605827
72Taste transduction_Homo sapiens_hsa047420.91138361
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.90953073
74Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.87812794
75Drug metabolism - other enzymes_Homo sapiens_hsa009830.87783181
76Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.87211753
77Wnt signaling pathway_Homo sapiens_hsa043100.86369020
78Gap junction_Homo sapiens_hsa045400.86301915
79Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.85878396
80Fatty acid degradation_Homo sapiens_hsa000710.85747043
81cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84388397
82Rheumatoid arthritis_Homo sapiens_hsa053230.83390714
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.79640744
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.78714017
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.78651984
86Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.75891027
87Nitrogen metabolism_Homo sapiens_hsa009100.74993642
88Arginine and proline metabolism_Homo sapiens_hsa003300.74163641
89Type II diabetes mellitus_Homo sapiens_hsa049300.73658809
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.71558612
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.70905910
92TGF-beta signaling pathway_Homo sapiens_hsa043500.70183260
93Estrogen signaling pathway_Homo sapiens_hsa049150.68061765
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.67785229
95Hippo signaling pathway_Homo sapiens_hsa043900.67382243
96Hedgehog signaling pathway_Homo sapiens_hsa043400.67380029
97Glycerolipid metabolism_Homo sapiens_hsa005610.66908567
98Peroxisome_Homo sapiens_hsa041460.66332555
99Oxidative phosphorylation_Homo sapiens_hsa001900.64675480
100ErbB signaling pathway_Homo sapiens_hsa040120.60751643
101Phagosome_Homo sapiens_hsa041450.60357249
102Proteasome_Homo sapiens_hsa030500.60309403
103beta-Alanine metabolism_Homo sapiens_hsa004100.59855000
104Basal cell carcinoma_Homo sapiens_hsa052170.59808602
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59785860
106Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.58454741
107Dilated cardiomyopathy_Homo sapiens_hsa054140.58362308
108Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.57149478
109Tight junction_Homo sapiens_hsa045300.57074042
110Bile secretion_Homo sapiens_hsa049760.56866949
111Thyroid hormone synthesis_Homo sapiens_hsa049180.56864643
112Starch and sucrose metabolism_Homo sapiens_hsa005000.56593255
113Propanoate metabolism_Homo sapiens_hsa006400.55847797
114Prion diseases_Homo sapiens_hsa050200.55617703
115African trypanosomiasis_Homo sapiens_hsa051430.55563599
116Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55129277
117NOD-like receptor signaling pathway_Homo sapiens_hsa046210.50847294
118Metabolic pathways_Homo sapiens_hsa011000.50242979
119MAPK signaling pathway_Homo sapiens_hsa040100.48930686
120Alzheimers disease_Homo sapiens_hsa050100.46834796
121Pancreatic secretion_Homo sapiens_hsa049720.45792302
1222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45233561
123Histidine metabolism_Homo sapiens_hsa003400.45036459
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43663328
125Mineral absorption_Homo sapiens_hsa049780.43117820
126Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.42245091
127Inositol phosphate metabolism_Homo sapiens_hsa005620.41462117
128Arginine biosynthesis_Homo sapiens_hsa002200.41093883
129Ribosome_Homo sapiens_hsa030100.40626106
130Arachidonic acid metabolism_Homo sapiens_hsa005900.40366224
131N-Glycan biosynthesis_Homo sapiens_hsa005100.37844251
132Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.37374645
133Dorso-ventral axis formation_Homo sapiens_hsa043200.37208359
134Glutathione metabolism_Homo sapiens_hsa004800.37090905
135Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.36637324
136Rap1 signaling pathway_Homo sapiens_hsa040150.36088202
137Sulfur metabolism_Homo sapiens_hsa009200.33788534
138Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.31113639
139Ras signaling pathway_Homo sapiens_hsa040140.30793023
140Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.28430352
141Fatty acid biosynthesis_Homo sapiens_hsa000610.26759113

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