GMNN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)5.34074014
2DNA replication checkpoint (GO:0000076)5.30508012
3telomere maintenance via semi-conservative replication (GO:0032201)5.14015001
4DNA replication initiation (GO:0006270)5.11811643
5mitotic metaphase plate congression (GO:0007080)5.10501784
6DNA strand elongation (GO:0022616)5.07590523
7telomere maintenance via recombination (GO:0000722)4.73404476
8CENP-A containing nucleosome assembly (GO:0034080)4.66652737
9protein localization to kinetochore (GO:0034501)4.66591795
10chromatin remodeling at centromere (GO:0031055)4.57403455
11purine nucleobase biosynthetic process (GO:0009113)4.56388376
12nucleobase biosynthetic process (GO:0046112)4.54205378
13establishment of integrated proviral latency (GO:0075713)4.53441235
14mitotic recombination (GO:0006312)4.48173044
15regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.34283617
16metaphase plate congression (GO:0051310)4.32774505
17DNA deamination (GO:0045006)4.23713544
18DNA unwinding involved in DNA replication (GO:0006268)4.19215300
19DNA replication-independent nucleosome assembly (GO:0006336)4.19167660
20DNA replication-independent nucleosome organization (GO:0034724)4.19167660
21mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.18422328
22protein localization to chromosome, centromeric region (GO:0071459)4.13372669
23telomere maintenance via telomere lengthening (GO:0010833)4.08613376
24attachment of spindle microtubules to kinetochore (GO:0008608)4.06548334
25kinetochore organization (GO:0051383)4.03355990
26maturation of SSU-rRNA (GO:0030490)3.96633870
27histone exchange (GO:0043486)3.96011250
28DNA replication-dependent nucleosome assembly (GO:0006335)3.88882740
29DNA replication-dependent nucleosome organization (GO:0034723)3.88882740
30nucleotide-excision repair, DNA gap filling (GO:0006297)3.87254794
31negative regulation of ligase activity (GO:0051352)3.85745458
32negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.85745458
33establishment of chromosome localization (GO:0051303)3.83952284
34chaperone-mediated protein transport (GO:0072321)3.81212917
35kinetochore assembly (GO:0051382)3.81028792
36ribosome assembly (GO:0042255)3.79847219
37ribosomal small subunit assembly (GO:0000028)3.77916385
38ribosome biogenesis (GO:0042254)3.77460936
39formation of translation preinitiation complex (GO:0001731)3.76761068
40mitotic nuclear envelope disassembly (GO:0007077)3.75276513
41DNA ligation (GO:0006266)3.75127396
42establishment of protein localization to mitochondrial membrane (GO:0090151)3.67982676
43mitotic chromosome condensation (GO:0007076)3.66114652
44regulation of double-strand break repair via homologous recombination (GO:0010569)3.58232646
45regulation of spindle organization (GO:0090224)3.58208864
46IMP biosynthetic process (GO:0006188)3.54081663
47spliceosomal snRNP assembly (GO:0000387)3.51613797
48meiotic chromosome segregation (GO:0045132)3.51590833
49energy coupled proton transport, down electrochemical gradient (GO:0015985)3.51155881
50ATP synthesis coupled proton transport (GO:0015986)3.51155881
51mitotic sister chromatid segregation (GO:0000070)3.51128777
52establishment of viral latency (GO:0019043)3.50445823
53ribonucleoprotein complex biogenesis (GO:0022613)3.49960174
54deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.47120812
55nuclear envelope disassembly (GO:0051081)3.44612603
56membrane disassembly (GO:0030397)3.44612603
57transcription-coupled nucleotide-excision repair (GO:0006283)3.42764185
58rRNA modification (GO:0000154)3.40735573
59anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.37898903
60regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.35954787
61regulation of nuclear cell cycle DNA replication (GO:0033262)3.35354086
62regulation of mitochondrial translation (GO:0070129)3.35206771
63rRNA processing (GO:0006364)3.34281920
64DNA double-strand break processing (GO:0000729)3.34212423
65positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.33201191
66proteasome assembly (GO:0043248)3.32347375
67ribosomal large subunit biogenesis (GO:0042273)3.31748776
68mitotic spindle checkpoint (GO:0071174)3.29345374
69protein K6-linked ubiquitination (GO:0085020)3.29126320
70nuclear pore organization (GO:0006999)3.28693920
71cell cycle G1/S phase transition (GO:0044843)3.28544057
72G1/S transition of mitotic cell cycle (GO:0000082)3.28544057
73spindle checkpoint (GO:0031577)3.28543985
74maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.28089707
75regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.26102156
76regulation of cellular amino acid metabolic process (GO:0006521)3.25709538
77signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.24792130
78signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.24792130
79signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.24792130
80DNA catabolic process, exonucleolytic (GO:0000738)3.24073484
81rRNA metabolic process (GO:0016072)3.23612490
82folic acid-containing compound biosynthetic process (GO:0009396)3.22941256
83positive regulation of chromosome segregation (GO:0051984)3.22660283
84DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.22546432
85cullin deneddylation (GO:0010388)3.22538704
86intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.21691101
87signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.21691101
88termination of RNA polymerase III transcription (GO:0006386)3.21010031
89transcription elongation from RNA polymerase III promoter (GO:0006385)3.21010031
90negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.19952457
91positive regulation of ligase activity (GO:0051351)3.19495852
92regulation of ubiquitin-protein transferase activity (GO:0051438)3.19006285
93folic acid metabolic process (GO:0046655)3.18767180
94signal transduction involved in DNA integrity checkpoint (GO:0072401)3.18465882
95signal transduction involved in DNA damage checkpoint (GO:0072422)3.18465882
96regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.17084690
97regulation of mitotic spindle checkpoint (GO:1903504)3.17084690
98regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.16548524
99mitotic spindle assembly checkpoint (GO:0007094)3.16030304
100positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.15837642
101replication fork processing (GO:0031297)3.14537494
102maturation of 5.8S rRNA (GO:0000460)3.14449910
103regulation of chromosome segregation (GO:0051983)3.14148016
104signal transduction involved in cell cycle checkpoint (GO:0072395)3.13393344
105IMP metabolic process (GO:0046040)3.12681572
106exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.12621491
107telomere organization (GO:0032200)3.12127589
108ribosomal small subunit biogenesis (GO:0042274)3.11815263
109pseudouridine synthesis (GO:0001522)3.11437787
110telomere maintenance (GO:0000723)3.11101160
111non-recombinational repair (GO:0000726)3.10549749
112double-strand break repair via nonhomologous end joining (GO:0006303)3.10549749
1137-methylguanosine mRNA capping (GO:0006370)3.09834618
114mismatch repair (GO:0006298)3.09812759
115negative regulation of chromosome segregation (GO:0051985)3.09737114
116deoxyribonucleotide biosynthetic process (GO:0009263)3.09680048
117negative regulation of mitotic sister chromatid separation (GO:2000816)3.08822335
118negative regulation of mitotic sister chromatid segregation (GO:0033048)3.08822335
119negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.08822335
120negative regulation of sister chromatid segregation (GO:0033046)3.08822335
121chromatin assembly or disassembly (GO:0006333)3.08787682
122regulation of ligase activity (GO:0051340)3.08013655
123sister chromatid segregation (GO:0000819)3.07811312
124DNA damage response, detection of DNA damage (GO:0042769)3.06864098
125translational termination (GO:0006415)3.06743224
126protein localization to chromosome (GO:0034502)3.06569757
127viral transcription (GO:0019083)3.06520000
128nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.06469674
1297-methylguanosine RNA capping (GO:0009452)3.05487277
130RNA capping (GO:0036260)3.05487277
131chromosome segregation (GO:0007059)3.04444741
132regulation of mitotic metaphase/anaphase transition (GO:0030071)3.03437589
133somatic hypermutation of immunoglobulin genes (GO:0016446)3.02231644
134somatic diversification of immune receptors via somatic mutation (GO:0002566)3.02231644
135spliceosomal complex assembly (GO:0000245)3.02147809
136spindle assembly checkpoint (GO:0071173)3.02108430
137negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.02001215
138ATP-dependent chromatin remodeling (GO:0043044)3.01885633
139translational initiation (GO:0006413)2.99688531

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.28008186
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.22866625
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.14770298
4* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.87582592
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.59086571
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.56677264
7* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.35068735
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.09756883
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.06266610
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.98169971
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.88714458
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.88255465
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.87605903
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.81282058
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78898307
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.53116365
17AR_21909140_ChIP-Seq_LNCAP_Human2.45881667
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.39591557
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.34722576
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.32701948
21MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.28992448
22XRN2_22483619_ChIP-Seq_HELA_Human2.28823518
23VDR_23849224_ChIP-Seq_CD4+_Human2.28246514
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.04395164
25* E2F1_21310950_ChIP-Seq_MCF-7_Human2.04195624
26NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.03265861
27DCP1A_22483619_ChIP-Seq_HELA_Human2.02879569
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.95051800
29FOXP3_21729870_ChIP-Seq_TREG_Human1.94958443
30GABP_19822575_ChIP-Seq_HepG2_Human1.91701152
31MYCN_18555785_ChIP-Seq_MESCs_Mouse1.89106066
32* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.88784948
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.85804417
34SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.82063834
35PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.81368352
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.80908854
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.78631807
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.76647858
39TTF2_22483619_ChIP-Seq_HELA_Human1.75980091
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71966118
41* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.70311861
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.69257148
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.63964091
44* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.62120736
45ELK1_19687146_ChIP-ChIP_HELA_Human1.61845719
46YY1_21170310_ChIP-Seq_MESCs_Mouse1.61525681
47SRF_21415370_ChIP-Seq_HL-1_Mouse1.52503155
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49646521
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.47548766
50* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46081666
51KDM5A_27292631_Chip-Seq_BREAST_Human1.42158335
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.39106240
53CIITA_25753668_ChIP-Seq_RAJI_Human1.37755089
54EGR1_19374776_ChIP-ChIP_THP-1_Human1.36771102
55ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.35766040
56SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25230301
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.25167201
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.21549678
59ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20495842
60KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20166187
61E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19948214
62FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18881159
63CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17495968
64PADI4_21655091_ChIP-ChIP_MCF-7_Human1.17263997
65PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.16318078
66STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15768095
67MYC_22102868_ChIP-Seq_BL_Human1.14740222
68NANOG_16153702_ChIP-ChIP_HESCs_Human1.11956900
69* HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.10520018
70POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09063645
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.05897572
72TP63_19390658_ChIP-ChIP_HaCaT_Human1.05279029
73* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.03180500
74ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02946746
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.01818007
76BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.99547648
77SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.98320336
78* MYC_18940864_ChIP-ChIP_HL60_Human0.97957375
79* TFEB_21752829_ChIP-Seq_HELA_Human0.97183500
80* SOX2_18555785_ChIP-Seq_MESCs_Mouse0.96835820
81NOTCH1_21737748_ChIP-Seq_TLL_Human0.96775109
82* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.96185485
83SOX17_20123909_ChIP-Seq_XEN_Mouse0.94783655
84EWS_26573619_Chip-Seq_HEK293_Human0.94287436
85POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94229446
86CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92548503
87SOX2_16153702_ChIP-ChIP_HESCs_Human0.92409193
88KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91033364
89SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.89546688
90ELK1_22589737_ChIP-Seq_MCF10A_Human0.89439810
91SPI1_23547873_ChIP-Seq_NB4_Human0.87137918
92CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85573663
93CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.83639870
94GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.82276947
95CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81662431
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.81622914
97NANOG_21062744_ChIP-ChIP_HESCs_Human0.81295984
98* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.78929263
99CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.78610931
100SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.78213589
101* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.77932073
102IRF1_19129219_ChIP-ChIP_H3396_Human0.75325886
103HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.74142267
104RBPJ_22232070_ChIP-Seq_NCS_Mouse0.73484953
105NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.72353973
106VDR_21846776_ChIP-Seq_THP-1_Human0.72220637
107TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.71869423
108FUS_26573619_Chip-Seq_HEK293_Human0.71126588
109SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.70782001
110SOX2_18692474_ChIP-Seq_MEFs_Mouse0.70473732
111CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.70018107
112* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69181333
113* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.68538790
114* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.68066277
115* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.67463993
116ESR1_15608294_ChIP-ChIP_MCF-7_Human0.64222014
117TCF3_18692474_ChIP-Seq_MEFs_Mouse0.63750720
118ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.63659134

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.35269123
2MP0010094_abnormal_chromosome_stability5.19451113
3* MP0003111_abnormal_nucleus_morphology4.78359279
4MP0008057_abnormal_DNA_replication4.68586592
5* MP0004957_abnormal_blastocyst_morpholog4.58738762
6* MP0003077_abnormal_cell_cycle4.30734795
7MP0008058_abnormal_DNA_repair3.80059239
8MP0008007_abnormal_cellular_replicative3.05258787
9MP0008932_abnormal_embryonic_tissue2.92073318
10MP0008877_abnormal_DNA_methylation2.56679909
11MP0003123_paternal_imprinting2.43461645
12MP0002396_abnormal_hematopoietic_system2.33280840
13* MP0001730_embryonic_growth_arrest2.32831316
14MP0003718_maternal_effect2.25228209
15* MP0000350_abnormal_cell_proliferation2.21361507
16MP0003786_premature_aging2.10122512
17MP0010307_abnormal_tumor_latency1.88335355
18MP0000490_abnormal_crypts_of1.76228756
19MP0003806_abnormal_nucleotide_metabolis1.72891621
20MP0001697_abnormal_embryo_size1.71202722
21* MP0001672_abnormal_embryogenesis/_devel1.71171577
22* MP0005380_embryogenesis_phenotype1.71171577
23* MP0002080_prenatal_lethality1.56452696
24MP0003984_embryonic_growth_retardation1.56430086
25MP0000313_abnormal_cell_death1.53689016
26MP0010352_gastrointestinal_tract_polyps1.52308439
27MP0002088_abnormal_embryonic_growth/wei1.51497490
28MP0009333_abnormal_splenocyte_physiolog1.48979641
29MP0002019_abnormal_tumor_incidence1.48097569
30MP0002210_abnormal_sex_determination1.47670218
31MP0002938_white_spotting1.47110282
32MP0003136_yellow_coat_color1.43666418
33* MP0002085_abnormal_embryonic_tissue1.41681377
34MP0003567_abnormal_fetal_cardiomyocyte1.36932669
35MP0003315_abnormal_perineum_morphology1.34830980
36MP0003186_abnormal_redox_activity1.32928366
37MP0009379_abnormal_foot_pigmentation1.29851188
38MP0001145_abnormal_male_reproductive1.26003058
39MP0006292_abnormal_olfactory_placode1.25723611
40MP0001929_abnormal_gametogenesis1.25670268
41MP0004808_abnormal_hematopoietic_stem1.24992334
42MP0000372_irregular_coat_pigmentation1.23966836
43MP0001529_abnormal_vocalization1.22849647
44MP0002084_abnormal_developmental_patter1.22044010
45MP0005397_hematopoietic_system_phenotyp1.21902500
46MP0001545_abnormal_hematopoietic_system1.21902500
47* MP0002086_abnormal_extraembryonic_tissu1.21689647
48MP0008789_abnormal_olfactory_epithelium1.16285775
49MP0006072_abnormal_retinal_apoptosis1.15933047
50MP0003221_abnormal_cardiomyocyte_apopto1.14043283
51MP0000653_abnormal_sex_gland1.13295371
52MP0006036_abnormal_mitochondrial_physio1.12414928
53MP0004197_abnormal_fetal_growth/weight/1.07768178
54MP0001286_abnormal_eye_development1.03873513
55MP0002160_abnormal_reproductive_system1.03205636
56MP0003121_genomic_imprinting1.02575303
57MP0002697_abnormal_eye_size1.02232872
58MP0001119_abnormal_female_reproductive1.01820001
59MP0003890_abnormal_embryonic-extraembry0.99616597
60MP0003763_abnormal_thymus_physiology0.97828369
61MP0000689_abnormal_spleen_morphology0.95333196
62* MP0002398_abnormal_bone_marrow0.94928533
63MP0002722_abnormal_immune_system0.94903410
64MP0002132_abnormal_respiratory_system0.93276468
65MP0001293_anophthalmia0.92976306
66MP0000358_abnormal_cell_content/0.91134111
67* MP0000703_abnormal_thymus_morphology0.87381819
68MP0002233_abnormal_nose_morphology0.87114194
69MP0002102_abnormal_ear_morphology0.84229493
70MP0000049_abnormal_middle_ear0.82338611
71MP0005389_reproductive_system_phenotype0.81834586
72MP0005451_abnormal_body_composition0.80599561
73MP0009672_abnormal_birth_weight0.79491299
74MP0003656_abnormal_erythrocyte_physiolo0.78984109
75* MP0002429_abnormal_blood_cell0.78168277
76MP0001346_abnormal_lacrimal_gland0.77454205
77MP0001188_hyperpigmentation0.76693747
78MP0000647_abnormal_sebaceous_gland0.76235379
79* MP0005384_cellular_phenotype0.75537437
80MP0005499_abnormal_olfactory_system0.74713520
81MP0005394_taste/olfaction_phenotype0.74713520
82MP0003941_abnormal_skin_development0.74561440
83MP0006035_abnormal_mitochondrial_morpho0.74450131
84MP0002234_abnormal_pharynx_morphology0.72548766
85MP0001661_extended_life_span0.71272513
86MP0000858_altered_metastatic_potential0.71111119
87MP0004147_increased_porphyrin_level0.71058841
88MP0005266_abnormal_metabolism0.69934716
89* MP0005621_abnormal_cell_physiology0.69632482
90MP0008260_abnormal_autophagy0.69243008
91MP0001853_heart_inflammation0.68773716
92MP0002163_abnormal_gland_morphology0.68150411
93MP0005408_hypopigmentation0.67973948
94MP0003699_abnormal_female_reproductive0.65293665
95MP0006054_spinal_hemorrhage0.65250642
96MP0002653_abnormal_ependyma_morphology0.64616015
97MP0003937_abnormal_limbs/digits/tail_de0.64435560
98MP0000537_abnormal_urethra_morphology0.64428564
99MP0002736_abnormal_nociception_after0.63771031
100MP0005391_vision/eye_phenotype0.63698680
101MP0002090_abnormal_vision0.63498269
102* MP0000716_abnormal_immune_system0.61490724
103MP0003119_abnormal_digestive_system0.61394231
104MP0002092_abnormal_eye_morphology0.60807541
105MP0004084_abnormal_cardiac_muscle0.60444526
106MP0005395_other_phenotype0.60358118
107MP0005084_abnormal_gallbladder_morpholo0.60079291
108MP0003646_muscle_fatigue0.59121192
109MP0003698_abnormal_male_reproductive0.58941511
110MP0000579_abnormal_nail_morphology0.58420906
111MP0002111_abnormal_tail_morphology0.57877202
112MP0002161_abnormal_fertility/fecundity0.57299017
113MP0005253_abnormal_eye_physiology0.56155747
114MP0001881_abnormal_mammary_gland0.56129791
115MP0003755_abnormal_palate_morphology0.55793013
116MP0008995_early_reproductive_senescence0.55429082
117MP0004133_heterotaxia0.54766279
118MP0010030_abnormal_orbit_morphology0.54243494
119MP0003861_abnormal_nervous_system0.53348474
120MP0000477_abnormal_intestine_morphology0.52408706
121MP0001727_abnormal_embryo_implantation0.52015071
122MP0009053_abnormal_anal_canal0.51891393
123MP0005075_abnormal_melanosome_morpholog0.51791880
124MP0005501_abnormal_skin_physiology0.51713183
125MP0000631_abnormal_neuroendocrine_gland0.50801457
126MP0001764_abnormal_homeostasis0.49330557
127MP0009697_abnormal_copulation0.49221598
128MP0001919_abnormal_reproductive_system0.48881158
129MP0000750_abnormal_muscle_regeneration0.48555602
130MP0001915_intracranial_hemorrhage0.47653844
131MP0009703_decreased_birth_body0.46320378
132MP0002095_abnormal_skin_pigmentation0.46149348
133MP0004264_abnormal_extraembryonic_tissu0.43893250

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)6.53602723
2Breast hypoplasia (HP:0003187)5.14254514
3Chromsome breakage (HP:0040012)4.49502357
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.40743471
5Reticulocytopenia (HP:0001896)4.12726276
6Patellar aplasia (HP:0006443)4.01880787
7Abnormality of cells of the erythroid lineage (HP:0012130)4.01570620
8Acute necrotizing encephalopathy (HP:0006965)3.99425261
9Abnormal number of erythroid precursors (HP:0012131)3.98140745
10Oral leukoplakia (HP:0002745)3.94552119
11Aplasia/Hypoplasia of the patella (HP:0006498)3.79306343
12Acute encephalopathy (HP:0006846)3.74003138
13Abnormal mitochondria in muscle tissue (HP:0008316)3.73341189
14Carpal bone hypoplasia (HP:0001498)3.71991115
15Meckel diverticulum (HP:0002245)3.68083381
16Abnormality of chromosome stability (HP:0003220)3.63562933
17Abnormality of the preputium (HP:0100587)3.61151283
18Abnormality of the ileum (HP:0001549)3.46440955
19Mitochondrial inheritance (HP:0001427)3.34534616
20Increased CSF lactate (HP:0002490)3.32418164
21Aplastic anemia (HP:0001915)3.29746969
22Increased hepatocellular lipid droplets (HP:0006565)3.28697790
23Impulsivity (HP:0100710)3.24408811
24Rough bone trabeculation (HP:0100670)3.22308981
25Aplasia/Hypoplasia of the uvula (HP:0010293)3.21006323
26Progressive macrocephaly (HP:0004481)3.15921486
27Cerebral hypomyelination (HP:0006808)3.12849691
28Degeneration of anterior horn cells (HP:0002398)3.08626819
29Abnormality of the anterior horn cell (HP:0006802)3.08626819
30Colon cancer (HP:0003003)3.01448217
31Hepatocellular necrosis (HP:0001404)2.95054989
32Microretrognathia (HP:0000308)2.94785334
33Cerebral edema (HP:0002181)2.92992354
34Lipid accumulation in hepatocytes (HP:0006561)2.89752927
35Duodenal stenosis (HP:0100867)2.88680205
36Small intestinal stenosis (HP:0012848)2.88680205
37Absent radius (HP:0003974)2.87907252
38Selective tooth agenesis (HP:0001592)2.87684372
39Bone marrow hypocellularity (HP:0005528)2.83794459
40Macrocytic anemia (HP:0001972)2.81295556
41Absent thumb (HP:0009777)2.79475168
42Increased serum pyruvate (HP:0003542)2.78560061
43Hepatic necrosis (HP:0002605)2.75519251
44Myelodysplasia (HP:0002863)2.74694970
45Agnosia (HP:0010524)2.73706356
46Multiple enchondromatosis (HP:0005701)2.72709688
47Medulloblastoma (HP:0002885)2.69314411
48Abnormality of glycolysis (HP:0004366)2.66987761
49Aplasia involving forearm bones (HP:0009822)2.66788670
50Absent forearm bone (HP:0003953)2.66788670
51Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.59660789
52Premature graying of hair (HP:0002216)2.59473035
53Microvesicular hepatic steatosis (HP:0001414)2.58951820
54Pallor (HP:0000980)2.50465236
55Horseshoe kidney (HP:0000085)2.47493222
56Secondary amenorrhea (HP:0000869)2.47274617
57Abnormal spermatogenesis (HP:0008669)2.45395922
58Neoplasm of the pancreas (HP:0002894)2.44965984
59Ependymoma (HP:0002888)2.44531544
60Sloping forehead (HP:0000340)2.37767416
61Cleft eyelid (HP:0000625)2.36252815
62Cellular immunodeficiency (HP:0005374)2.35821058
63Ectopic kidney (HP:0000086)2.35564037
64Lactic acidosis (HP:0003128)2.35473929
65Tracheoesophageal fistula (HP:0002575)2.35165539
66Renal Fanconi syndrome (HP:0001994)2.35086348
67Abnormality of the labia minora (HP:0012880)2.34476915
68Abnormal lung lobation (HP:0002101)2.33576576
69Abnormality of methionine metabolism (HP:0010901)2.33412480
70Triphalangeal thumb (HP:0001199)2.30840342
71Abnormal trabecular bone morphology (HP:0100671)2.30523373
72Abnormality of the duodenum (HP:0002246)2.30061243
7311 pairs of ribs (HP:0000878)2.28570094
74Duplicated collecting system (HP:0000081)2.28437338
75Premature ovarian failure (HP:0008209)2.28311892
76Pancytopenia (HP:0001876)2.26791318
77Hypoplasia of the capital femoral epiphysis (HP:0003090)2.25941081
78Hyperglycinemia (HP:0002154)2.24495990
79Abnormality of the heme biosynthetic pathway (HP:0010472)2.20758551
80Embryonal renal neoplasm (HP:0011794)2.19710233
81Increased intramyocellular lipid droplets (HP:0012240)2.19188600
82Increased nuchal translucency (HP:0010880)2.19055354
83Supernumerary spleens (HP:0009799)2.18680376
84Slender long bone (HP:0003100)2.17790860
85Abnormality of serum amino acid levels (HP:0003112)2.17424759
86Rhabdomyosarcoma (HP:0002859)2.15975735
87Clubbing of toes (HP:0100760)2.14064106
88Atresia of the external auditory canal (HP:0000413)2.13856498
89Trismus (HP:0000211)2.13486058
90Aplasia/Hypoplasia of the sacrum (HP:0008517)2.12815281
91Short thumb (HP:0009778)2.11924635
92Leukodystrophy (HP:0002415)2.11829779
93Exercise intolerance (HP:0003546)2.08560652
94Respiratory failure (HP:0002878)2.07257573
95Facial cleft (HP:0002006)2.07162800
96Facial hemangioma (HP:0000329)2.07000305
97Squamous cell carcinoma (HP:0002860)2.05744220
98Abnormality of the carotid arteries (HP:0005344)2.05469041
99Volvulus (HP:0002580)2.04475057
100Abnormality of the renal collecting system (HP:0004742)2.03684186
101Megaloblastic anemia (HP:0001889)2.02713671
102Respiratory difficulties (HP:0002880)2.01940886
103Abnormality of pyrimidine metabolism (HP:0004353)1.98784425
104Progressive muscle weakness (HP:0003323)1.98314302
105Abnormal number of incisors (HP:0011064)1.97405507
106Lymphoma (HP:0002665)1.95533434
107Decreased activity of mitochondrial respiratory chain (HP:0008972)1.95235289
108Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.95235289
109Breast aplasia (HP:0100783)1.95000060
110Ureteral duplication (HP:0000073)1.93300043
111Reduced antithrombin III activity (HP:0001976)1.93033459
112Increased serum lactate (HP:0002151)1.92048099
113Cafe-au-lait spot (HP:0000957)1.90545228
114CNS hypomyelination (HP:0003429)1.89404192
115Aplasia/Hypoplasia of the breasts (HP:0010311)1.88595559
1163-Methylglutaconic aciduria (HP:0003535)1.88443665
117Abnormality of cochlea (HP:0000375)1.87420307
118Abnormality of aspartate family amino acid metabolism (HP:0010899)1.85598816
119Methylmalonic acidemia (HP:0002912)1.84593924
120Postnatal microcephaly (HP:0005484)1.84098230
121Aplasia/Hypoplasia of the sternum (HP:0006714)1.83785460
122Abnormality of alanine metabolism (HP:0010916)1.83233792
123Hyperalaninemia (HP:0003348)1.83233792
124Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.83233792
125Methylmalonic aciduria (HP:0012120)1.82035282
126Abnormality of reticulocytes (HP:0004312)1.81357939
127Abnormal protein glycosylation (HP:0012346)1.81074715
128Abnormal glycosylation (HP:0012345)1.81074715
129Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.81074715
130Abnormal protein N-linked glycosylation (HP:0012347)1.81074715
131Sparse eyelashes (HP:0000653)1.80885194
132Lethargy (HP:0001254)1.79683067
133Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.78625543
134Exertional dyspnea (HP:0002875)1.78619392
135Nephroblastoma (Wilms tumor) (HP:0002667)1.78138861
136Nausea (HP:0002018)1.77439255
137Cortical dysplasia (HP:0002539)1.77103905
138Basal cell carcinoma (HP:0002671)1.76190645
139Poor head control (HP:0002421)1.75982593
140Type I transferrin isoform profile (HP:0003642)1.74182285
141Hypoplasia of the radius (HP:0002984)1.73298106
142Muscle fiber atrophy (HP:0100295)1.72806789
143Neoplasm of the colon (HP:0100273)1.72633173
144Azoospermia (HP:0000027)1.72192715
145Thrombocytosis (HP:0001894)1.71875343

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.99652519
2BUB14.88644972
3CDC74.49163624
4VRK23.48048745
5EIF2AK13.46645189
6PLK42.98350211
7SRPK12.90096945
8NEK22.85830645
9BRSK22.77492350
10NME22.57218461
11ACVR1B2.54875824
12TTK2.50323999
13NEK12.41046394
14EIF2AK32.26381386
15PLK12.24464917
16STK162.05582248
17VRK12.04311536
18AURKB1.81646819
19BRSK11.80085578
20TSSK61.69808293
21TRIM281.68943362
22CCNB11.68505601
23PLK31.68391519
24TESK21.66881223
25DYRK31.64373950
26CDK71.63607356
27ATR1.57790533
28CHEK21.53777962
29MKNK11.53682135
30TAF11.41783444
31NUAK11.39136091
32RPS6KA41.38011491
33TLK11.36789431
34PDK21.33599634
35PASK1.28061457
36CDK41.27265606
37MAP3K81.25978435
38MKNK21.24455659
39STK41.22657792
40CHEK11.17244972
41ZAK1.10714372
42RPS6KB21.08353459
43* AURKA1.03737053
44EIF2AK20.95784775
45STK38L0.93868846
46BMPR1B0.93818528
47STK100.89232937
48SCYL20.87909231
49BRAF0.87789552
50TNIK0.86327617
51PBK0.82652274
52PIM10.81958087
53ATM0.81358612
54EPHA20.81193087
55CDK20.77130861
56WNK30.76686776
57PAK40.75307651
58CDK80.72737084
59PIM20.70918472
60MELK0.69616460
61CSNK1G10.67411522
62* CSNK2A10.66926891
63CSNK2A20.64479629
64PAK10.63966511
65STK30.62962771
66CSNK1G30.62799972
67DYRK20.61636749
68CDK10.60423269
69LATS20.60416485
70CLK10.57513740
71ABL20.57361881
72BCKDK0.56411601
73DAPK10.54780133
74TGFBR10.54730342
75CDK120.54129261
76KDR0.53826330
77PLK20.53430287
78MAP4K20.53232902
79PRKCI0.51184209
80CSNK1G20.46336044
81MAP2K30.45981333
82PDK30.44516136
83PDK40.44516136
84RPS6KA50.44273051
85CSNK1A1L0.42695092
86MAP4K10.42327754
87BCR0.41891595
88ERBB40.41667096
89NME10.41280328
90IRAK30.41184891
91MAP3K100.41109079
92TESK10.40840916
93CDK60.40605747
94ALK0.40483516
95FLT30.40155642
96STK240.39690456
97MST40.38726456
98NEK90.38600329
99CDK30.37004272
100LRRK20.36683604
101MAP3K110.36604432
102ERBB30.33574354
103MAP3K120.33070319
104IRAK40.31896775
105FGFR10.31543976
106TEC0.29908559
107MAP3K60.29856926
108CDK180.29459280
109TYK20.29016575
110MARK30.28203069
111MAPKAPK30.27976214
112CDK11A0.26969412
113CDK150.26947001
114OXSR10.26889198
115CDK140.26277214
116MAP3K50.25443036
117CDK90.25006804
118PNCK0.23655749
119RAF10.23102958
120AKT20.21962936
121MAPKAPK50.21717274
122PRKDC0.21690697
123BRD40.21237292
124CSNK1E0.20009000
125STK390.20008315
126EEF2K0.20002610
127SMG10.19692045
128MAP3K30.19430824
129ILK0.17499825
130TAOK20.15887280
131YES10.15166266

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.44147349
2Mismatch repair_Homo sapiens_hsa034304.47190385
3RNA polymerase_Homo sapiens_hsa030203.67446612
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.65875889
5Proteasome_Homo sapiens_hsa030503.46350653
6Homologous recombination_Homo sapiens_hsa034403.40610448
7Ribosome_Homo sapiens_hsa030103.23973983
8Spliceosome_Homo sapiens_hsa030403.13077092
9Base excision repair_Homo sapiens_hsa034103.10474354
10RNA transport_Homo sapiens_hsa030132.99741616
11Nucleotide excision repair_Homo sapiens_hsa034202.98426924
12Cell cycle_Homo sapiens_hsa041102.89362960
13Pyrimidine metabolism_Homo sapiens_hsa002402.77762915
14Fanconi anemia pathway_Homo sapiens_hsa034602.44056089
15One carbon pool by folate_Homo sapiens_hsa006702.39552456
16Basal transcription factors_Homo sapiens_hsa030222.12402354
17Non-homologous end-joining_Homo sapiens_hsa034502.09065173
18RNA degradation_Homo sapiens_hsa030181.91397800
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.89292563
20p53 signaling pathway_Homo sapiens_hsa041151.65375011
21Purine metabolism_Homo sapiens_hsa002301.53676423
22mRNA surveillance pathway_Homo sapiens_hsa030151.46941022
23Pyruvate metabolism_Homo sapiens_hsa006201.44977557
24Vitamin B6 metabolism_Homo sapiens_hsa007501.37280205
25Propanoate metabolism_Homo sapiens_hsa006401.27150520
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.21664685
27Fatty acid elongation_Homo sapiens_hsa000621.16274579
28Epstein-Barr virus infection_Homo sapiens_hsa051691.13392049
29Steroid biosynthesis_Homo sapiens_hsa001001.10989841
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.10469283
31Folate biosynthesis_Homo sapiens_hsa007901.08988966
32Pentose phosphate pathway_Homo sapiens_hsa000301.08033174
33Oocyte meiosis_Homo sapiens_hsa041141.01352771
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.97236820
35Cysteine and methionine metabolism_Homo sapiens_hsa002700.94543150
36Drug metabolism - other enzymes_Homo sapiens_hsa009830.90945093
37Systemic lupus erythematosus_Homo sapiens_hsa053220.90327239
38Huntingtons disease_Homo sapiens_hsa050160.88840977
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.86739944
40Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.85406276
41Biosynthesis of amino acids_Homo sapiens_hsa012300.85088494
42Herpes simplex infection_Homo sapiens_hsa051680.83688332
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79080470
44Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.77819824
45Protein export_Homo sapiens_hsa030600.76947468
46Antigen processing and presentation_Homo sapiens_hsa046120.72403202
47Parkinsons disease_Homo sapiens_hsa050120.70615530
48Selenocompound metabolism_Homo sapiens_hsa004500.70197464
49Glutathione metabolism_Homo sapiens_hsa004800.69980870
50Viral carcinogenesis_Homo sapiens_hsa052030.67396592
51Sulfur relay system_Homo sapiens_hsa041220.63220705
52Cardiac muscle contraction_Homo sapiens_hsa042600.60413716
53Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.59904272
54Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59703573
55Cyanoamino acid metabolism_Homo sapiens_hsa004600.59636661
56Carbon metabolism_Homo sapiens_hsa012000.58075972
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.55800065
58HTLV-I infection_Homo sapiens_hsa051660.54026870
59Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53052167
60Oxidative phosphorylation_Homo sapiens_hsa001900.52167504
61Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51085590
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48739906
63Sulfur metabolism_Homo sapiens_hsa009200.44567166
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42635120
65Fatty acid metabolism_Homo sapiens_hsa012120.42602069
66Thyroid cancer_Homo sapiens_hsa052160.41702610
67Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.41675603
68Butanoate metabolism_Homo sapiens_hsa006500.41531158
69Small cell lung cancer_Homo sapiens_hsa052220.41184604
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40935565
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40782138
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39108992
73Peroxisome_Homo sapiens_hsa041460.38894019
74Fatty acid degradation_Homo sapiens_hsa000710.38355219
75Legionellosis_Homo sapiens_hsa051340.37127127
76Metabolic pathways_Homo sapiens_hsa011000.36519596
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.35034868
78MicroRNAs in cancer_Homo sapiens_hsa052060.34605307
79Primary immunodeficiency_Homo sapiens_hsa053400.31300024
80Fructose and mannose metabolism_Homo sapiens_hsa000510.29095383
81N-Glycan biosynthesis_Homo sapiens_hsa005100.29055414
82Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28617442
83Apoptosis_Homo sapiens_hsa042100.28538348
84beta-Alanine metabolism_Homo sapiens_hsa004100.27454029
85Regulation of autophagy_Homo sapiens_hsa041400.26302155
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.25907233
87Galactose metabolism_Homo sapiens_hsa000520.25568226
88Tryptophan metabolism_Homo sapiens_hsa003800.25048774
89Arachidonic acid metabolism_Homo sapiens_hsa005900.24212525
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.23980403
91TGF-beta signaling pathway_Homo sapiens_hsa043500.21721583
92Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.19863025
93Tyrosine metabolism_Homo sapiens_hsa003500.19666359
94Measles_Homo sapiens_hsa051620.19617140
95Hepatitis B_Homo sapiens_hsa051610.19368291
96Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.19116325
97Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19095935
98Lysine degradation_Homo sapiens_hsa003100.18759521
99Arginine and proline metabolism_Homo sapiens_hsa003300.18213907
100Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.16446751
101Retinol metabolism_Homo sapiens_hsa008300.14988177
102NF-kappa B signaling pathway_Homo sapiens_hsa040640.14938290
103Intestinal immune network for IgA production_Homo sapiens_hsa046720.14842811
104Shigellosis_Homo sapiens_hsa051310.14702986
105Transcriptional misregulation in cancer_Homo sapiens_hsa052020.14657200
106Alzheimers disease_Homo sapiens_hsa050100.13157060
107Influenza A_Homo sapiens_hsa051640.11803937
108Alcoholism_Homo sapiens_hsa050340.11701477
109Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.11412400
110HIF-1 signaling pathway_Homo sapiens_hsa040660.11179114
111Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.11178520
112Linoleic acid metabolism_Homo sapiens_hsa005910.10703639
113Chemical carcinogenesis_Homo sapiens_hsa052040.09892211
114Arginine biosynthesis_Homo sapiens_hsa002200.09622336
115Fat digestion and absorption_Homo sapiens_hsa049750.08895923
116Vitamin digestion and absorption_Homo sapiens_hsa049770.07735961
117Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.07458570
118NOD-like receptor signaling pathway_Homo sapiens_hsa046210.07420529
119Caffeine metabolism_Homo sapiens_hsa002320.07392705
120Hippo signaling pathway_Homo sapiens_hsa043900.07354512
121Colorectal cancer_Homo sapiens_hsa052100.07308995
122Wnt signaling pathway_Homo sapiens_hsa043100.06846592
123Nitrogen metabolism_Homo sapiens_hsa009100.06499899
124Renin-angiotensin system_Homo sapiens_hsa046140.05517523
125Hematopoietic cell lineage_Homo sapiens_hsa046400.05047075
126Hedgehog signaling pathway_Homo sapiens_hsa043400.04594439
127RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.03815432
128Pathways in cancer_Homo sapiens_hsa052000.03634596
129Bladder cancer_Homo sapiens_hsa052190.02250060
130Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.0117100
131Basal cell carcinoma_Homo sapiens_hsa05217-0.0116276

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »