GMPR2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.86968030
2viral transcription (GO:0019083)4.62946048
3translational termination (GO:0006415)4.51588477
4pinocytosis (GO:0006907)4.34130410
5DNA deamination (GO:0045006)4.29798939
6response to interferon-beta (GO:0035456)4.16937920
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.16122260
8cotranslational protein targeting to membrane (GO:0006613)4.10630103
9protein targeting to ER (GO:0045047)4.04955339
10translational elongation (GO:0006414)3.99199869
11DNA strand elongation involved in DNA replication (GO:0006271)3.94408511
12cellular response to interferon-beta (GO:0035458)3.92724546
13protein localization to endoplasmic reticulum (GO:0070972)3.86593648
14establishment of protein localization to endoplasmic reticulum (GO:0072599)3.82591189
15proteasome assembly (GO:0043248)3.81612913
16regulation of cholesterol esterification (GO:0010872)3.81244438
17regulation of superoxide anion generation (GO:0032928)3.78188300
18telomere maintenance via semi-conservative replication (GO:0032201)3.76251201
19DNA strand elongation (GO:0022616)3.74698202
20ribosomal small subunit biogenesis (GO:0042274)3.72992237
21maturation of SSU-rRNA (GO:0030490)3.67230710
22plasma lipoprotein particle assembly (GO:0034377)3.65897985
23very-low-density lipoprotein particle assembly (GO:0034379)3.53615090
24viral life cycle (GO:0019058)3.51770664
25antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.51392253
26deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.50486290
27cellular protein complex disassembly (GO:0043624)3.47625814
28nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.44845932
29platelet dense granule organization (GO:0060155)3.44618865
30antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.43363754
31NADPH regeneration (GO:0006740)3.42591229
32pentose-phosphate shunt (GO:0006098)3.41876636
33negative regulation of fibrinolysis (GO:0051918)3.40662243
34blood coagulation, intrinsic pathway (GO:0007597)3.38025140
35translational initiation (GO:0006413)3.36777651
36DNA unwinding involved in DNA replication (GO:0006268)3.35260635
37antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.33947295
38erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.32586701
39L-phenylalanine metabolic process (GO:0006558)3.32586701
40telomere maintenance via recombination (GO:0000722)3.31195817
41low-density lipoprotein particle remodeling (GO:0034374)3.29426756
42negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.25673110
43ribosomal large subunit biogenesis (GO:0042273)3.24819090
44cellular hyperosmotic response (GO:0071474)3.17046322
45protein-lipid complex assembly (GO:0065005)3.17005313
46positive regulation of B cell differentiation (GO:0045579)3.14998817
47establishment of integrated proviral latency (GO:0075713)3.10853046
48regulation of protein activation cascade (GO:2000257)3.09355163
49regulation of complement activation (GO:0030449)3.08547263
50translation (GO:0006412)3.07920197
51lymphoid progenitor cell differentiation (GO:0002320)3.07518439
52antigen processing and presentation of endogenous antigen (GO:0019883)3.03604428
53protein complex disassembly (GO:0043241)3.03119904
54regulation of apoptotic cell clearance (GO:2000425)3.01260699
55Arp2/3 complex-mediated actin nucleation (GO:0034314)3.01079650
56DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.97962018
57negative regulation of ligase activity (GO:0051352)2.97789537
58negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.97789537
59DNA replication initiation (GO:0006270)2.97428849
60formation of translation preinitiation complex (GO:0001731)2.96243998
61mitotic recombination (GO:0006312)2.96093514
62signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.95387229
63intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.95387229
64positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.94792253
65regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.94218638
66neutrophil activation involved in immune response (GO:0002283)2.93394901
67modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.93255015
68positive regulation by organism of defense response of other organism involved in symbiotic interact2.93255015
69modulation by symbiont of host immune response (GO:0052553)2.93255015
70positive regulation by symbiont of host defense response (GO:0052509)2.93255015
71modulation by symbiont of host defense response (GO:0052031)2.93255015
72modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.93255015
73endosome to melanosome transport (GO:0035646)2.91984261
74endosome to pigment granule transport (GO:0043485)2.91984261
75peptidyl-glutamic acid carboxylation (GO:0017187)2.89675120
76protein carboxylation (GO:0018214)2.89675120
77signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.89591335
78signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.89591335
79signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.89591335
80L-phenylalanine catabolic process (GO:0006559)2.89433973
81erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.89433973
82peptide catabolic process (GO:0043171)2.88412663
83regulation of fibrinolysis (GO:0051917)2.87613450
84macromolecular complex disassembly (GO:0032984)2.86055717
85leukocyte migration involved in inflammatory response (GO:0002523)2.85774064
86L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.85439492
87antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.84776542
88antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.84776542
89anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.83178953
90establishment of viral latency (GO:0019043)2.81825865
91fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.80917466
92regulation of mitochondrial translation (GO:0070129)2.80632103
93transcription elongation from RNA polymerase III promoter (GO:0006385)2.80420953
94termination of RNA polymerase III transcription (GO:0006386)2.80420953
95pseudouridine synthesis (GO:0001522)2.77729316
96signal transduction involved in DNA damage checkpoint (GO:0072422)2.76125457
97signal transduction involved in DNA integrity checkpoint (GO:0072401)2.76125457
98negative regulation of humoral immune response (GO:0002921)2.75575355
99negative regulation of myeloid cell apoptotic process (GO:0033033)2.75418636
100nuclear-transcribed mRNA catabolic process (GO:0000956)2.74190008
101production of molecular mediator involved in inflammatory response (GO:0002532)2.73763611
102positive regulation of triglyceride lipase activity (GO:0061365)2.72104858
103positive regulation of lipoprotein lipase activity (GO:0051006)2.72104858
104tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.72095701
105RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.72095701
106signal transduction involved in cell cycle checkpoint (GO:0072395)2.71429689
107detection of other organism (GO:0098543)2.71194334
108negative regulation of protein activation cascade (GO:2000258)2.70987106
109nucleotide-excision repair, DNA gap filling (GO:0006297)2.70650349
110regulation of cellular amino acid metabolic process (GO:0006521)2.69736098
111antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.69618832
112immunoglobulin mediated immune response (GO:0016064)2.68944148
113telomere maintenance via telomere lengthening (GO:0010833)2.67361804
114ribonucleoprotein complex biogenesis (GO:0022613)2.66789363
115positive regulation of fatty acid biosynthetic process (GO:0045723)2.66285728
116regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.65673253
117COPI coating of Golgi vesicle (GO:0048205)2.65464441
118Golgi transport vesicle coating (GO:0048200)2.65464441
119mast cell activation (GO:0045576)2.64614365
120cholesterol efflux (GO:0033344)2.62228430
121mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.62192059
122mitochondrial respiratory chain complex I assembly (GO:0032981)2.62192059
123NADH dehydrogenase complex assembly (GO:0010257)2.62192059
124L-ascorbic acid metabolic process (GO:0019852)2.61084875
125positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.60113503
126mRNA catabolic process (GO:0006402)2.59149942
127protein targeting to membrane (GO:0006612)2.59044515
128defense response to protozoan (GO:0042832)2.58817405
129antigen processing and presentation via MHC class Ib (GO:0002475)2.57391440
130detection of bacterium (GO:0016045)2.56635639
131detection of molecule of bacterial origin (GO:0032490)2.55071305
132detection of external biotic stimulus (GO:0098581)2.54727967
133negative regulation of complement activation (GO:0045916)2.54723445
134NADH metabolic process (GO:0006734)2.54079351
135proline biosynthetic process (GO:0006561)2.53431930
136glucose catabolic process (GO:0006007)2.52871134
137response to peptidoglycan (GO:0032494)2.51858218
138disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.51479052
139killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.51479052
140plasma lipoprotein particle organization (GO:0071827)2.48823737
141regulation of myeloid leukocyte mediated immunity (GO:0002886)2.48332566
142protein maturation by protein folding (GO:0022417)2.48177262
143CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.47529055
144RNA catabolic process (GO:0006401)2.46975120
1452-deoxyribonucleotide biosynthetic process (GO:0009265)2.46865656
146deoxyribose phosphate biosynthetic process (GO:0046385)2.46865656
147DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.46437107
148regulation of B cell differentiation (GO:0045577)2.46021088
149regulation of superoxide metabolic process (GO:0090322)2.45833529
150* purine-containing compound salvage (GO:0043101)2.45832739
151nucleobase biosynthetic process (GO:0046112)2.45358821
152rRNA processing (GO:0006364)2.45278937
153regulation of B cell receptor signaling pathway (GO:0050855)2.45185537
154histone mRNA metabolic process (GO:0008334)2.43227332
155IMP biosynthetic process (GO:0006188)2.43133183
156response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.43061758
157response to host immune response (GO:0052572)2.43061758
158alpha-linolenic acid metabolic process (GO:0036109)2.43034782
159pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.42885481
160response to host defenses (GO:0052200)2.42282739
161response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.42282739
162response to host (GO:0075136)2.42282739
163negative regulation of cell killing (GO:0031342)2.41369075
164negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.41369075
165B cell mediated immunity (GO:0019724)2.40615254
166regulation of translation in response to stress (GO:0043555)2.38962495
167response to protozoan (GO:0001562)2.38771408
168pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.38647646
169regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.37855087
170protein-lipid complex remodeling (GO:0034368)2.37498577
171macromolecular complex remodeling (GO:0034367)2.37498577
172plasma lipoprotein particle remodeling (GO:0034369)2.37498577
173pentose metabolic process (GO:0019321)2.34038259
174ribosome assembly (GO:0042255)2.31630867

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.55769440
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.86598023
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.70165224
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.50525008
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.41681421
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.33082198
7* GABP_17652178_ChIP-ChIP_JURKAT_Human3.26341114
8* EST1_17652178_ChIP-ChIP_JURKAT_Human3.12671293
9* NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.12074977
10ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.92073303
11* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.90214149
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.82296110
13SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.77453483
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.77278544
15* ETS1_20019798_ChIP-Seq_JURKAT_Human2.72353436
16IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.65973812
17IRF8_21731497_ChIP-ChIP_J774_Mouse2.65280056
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.64497513
19* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.61794892
20* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.43549004
21FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.42780522
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.35768030
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.31313738
24TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.29911496
25E2F4_17652178_ChIP-ChIP_JURKAT_Human2.27271707
26MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.24698034
27VDR_23849224_ChIP-Seq_CD4+_Human2.23338151
28HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.22322951
29* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.18549363
30CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.17712072
31CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.14051013
32SCL_19346495_ChIP-Seq_HPC-7_Human2.09215319
33* SRF_21415370_ChIP-Seq_HL-1_Mouse2.08288563
34MYC_19079543_ChIP-ChIP_MESCs_Mouse2.06290870
35XRN2_22483619_ChIP-Seq_HELA_Human2.04150414
36* HOXB4_20404135_ChIP-ChIP_EML_Mouse2.02460027
37RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.02305010
38FOXP3_21729870_ChIP-Seq_TREG_Human1.96735990
39E2F1_18555785_ChIP-Seq_MESCs_Mouse1.92783479
40FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.92204407
41* SPI1_23547873_ChIP-Seq_NB4_Human1.91132106
42ERG_20887958_ChIP-Seq_HPC-7_Mouse1.89267588
43DCP1A_22483619_ChIP-Seq_HELA_Human1.86857310
44* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.80060019
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.78084742
46NELFA_20434984_ChIP-Seq_ESCs_Mouse1.77397974
47* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.77266616
48* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.68928717
49ELK1_19687146_ChIP-ChIP_HELA_Human1.68757997
50TTF2_22483619_ChIP-Seq_HELA_Human1.63483340
51GABP_19822575_ChIP-Seq_HepG2_Human1.63056440
52PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.60789850
53MYB_21317192_ChIP-Seq_ERMYB_Mouse1.57949335
54STAT4_19710469_ChIP-ChIP_TH1__Mouse1.56802838
55PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.56138826
56GATA1_22025678_ChIP-Seq_K562_Human1.56114015
57YY1_21170310_ChIP-Seq_MESCs_Mouse1.53477053
58NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.51724000
59* HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.51037582
60VDR_21846776_ChIP-Seq_THP-1_Human1.50694666
61MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.48591984
62RXR_22158963_ChIP-Seq_LIVER_Mouse1.47301747
63E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.46132722
64CIITA_25753668_ChIP-Seq_RAJI_Human1.42829660
65PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41660696
66GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.39782236
67PPARA_22158963_ChIP-Seq_LIVER_Mouse1.38477846
68IRF8_27001747_Chip-Seq_BMDM_Mouse1.37845762
69TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.37455405
70FOXM1_23109430_ChIP-Seq_U2OS_Human1.36666730
71ZNF263_19887448_ChIP-Seq_K562_Human1.34017175
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.33360787
73MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.32340096
74MYC_22102868_ChIP-Seq_BL_Human1.31258009
75LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.31059954
76* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.28636882
77VDR_24763502_ChIP-Seq_THP-1_Human1.27075972
78NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.26149581
79SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.24479167
80ZFX_18555785_ChIP-Seq_MESCs_Mouse1.24072519
81ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.23945807
82CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.21893217
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17589516
84YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.17527514
85KLF4_18555785_ChIP-Seq_MESCs_Mouse1.17372644
86TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17127690
87RUNX1_22412390_ChIP-Seq_EML_Mouse1.17014463
88LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.16984719
89FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.16466053
90TFEB_21752829_ChIP-Seq_HELA_Human1.15849786
91GATA1_22383799_ChIP-Seq_G1ME_Mouse1.15805614
92IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.15704149
93* MYB_26560356_Chip-Seq_TH2_Human1.14129455
94NOTCH1_21737748_ChIP-Seq_TLL_Human1.13453518
95CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.11806599
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.11756621
97CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09915155
98AR_21909140_ChIP-Seq_LNCAP_Human1.08665975
99CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07933065
100RARG_19884340_ChIP-ChIP_MEFs_Mouse1.06839625
101POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.06671752
102NANOG_18555785_ChIP-Seq_MESCs_Mouse1.06191446
103FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.05975440
104MYCN_18555785_ChIP-Seq_MESCs_Mouse1.05085051
105E2F1_21310950_ChIP-Seq_MCF-7_Human1.03296387
106EGR1_19374776_ChIP-ChIP_THP-1_Human1.02070635
107NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.01960569
108UTX_26944678_Chip-Seq_JUKART_Human1.01890414
109GATA2_22383799_ChIP-Seq_G1ME_Mouse1.01823654
110POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.01523362
111MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.00904321
112* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00554013
113SPI1_23127762_ChIP-Seq_K562_Human1.00547706
114STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98962439
115SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98092075
116E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97918507
117CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96986116
118SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.96854808
119LXR_22158963_ChIP-Seq_LIVER_Mouse0.96410154
120* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.96333559
121MYB_26560356_Chip-Seq_TH1_Human0.95787607
122BRD4_27068464_Chip-Seq_AML-cells_Mouse0.93855768
123MYC_18940864_ChIP-ChIP_HL60_Human0.93778079
124MAF_26560356_Chip-Seq_TH1_Human0.92891346
125PU.1_20513432_ChIP-Seq_Bcells_Mouse0.87724416
126* KDM5A_27292631_Chip-Seq_BREAST_Human0.86993047

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.91395284
2MP0005360_urolithiasis3.44313397
3MP0002396_abnormal_hematopoietic_system3.21918735
4MP0005671_abnormal_response_to3.17536518
5MP0008260_abnormal_autophagy3.14188208
6MP0009785_altered_susceptibility_to3.10474914
7MP0002148_abnormal_hypersensitivity_rea2.87418531
8MP0000685_abnormal_immune_system2.86917179
9MP0003693_abnormal_embryo_hatching2.61520782
10MP0005025_abnormal_response_to2.58792109
11MP0003724_increased_susceptibility_to2.46793634
12MP0002419_abnormal_innate_immunity2.41896295
13MP0008058_abnormal_DNA_repair2.37535588
14MP0001853_heart_inflammation2.36813752
15MP0002139_abnormal_hepatobiliary_system2.36447112
16MP0010094_abnormal_chromosome_stability2.36198251
17MP0005000_abnormal_immune_tolerance2.34040388
18MP0003122_maternal_imprinting2.32954331
19MP0004147_increased_porphyrin_level2.32868623
20MP0002452_abnormal_antigen_presenting2.25313628
21MP0001800_abnormal_humoral_immune2.22731154
22MP0002723_abnormal_immune_serum2.16890869
23MP0005365_abnormal_bile_salt2.11822348
24MP0009333_abnormal_splenocyte_physiolog2.11624517
25MP0005058_abnormal_lysosome_morphology2.11472787
26MP0002420_abnormal_adaptive_immunity2.11348579
27MP0002398_abnormal_bone_marrow2.10508187
28MP0001819_abnormal_immune_cell2.09922996
29MP0003436_decreased_susceptibility_to2.08099406
30MP0008007_abnormal_cellular_replicative2.04144422
31MP0003077_abnormal_cell_cycle2.03690177
32MP0005464_abnormal_platelet_physiology2.01082930
33MP0003763_abnormal_thymus_physiology2.00456865
34MP0000490_abnormal_crypts_of1.97873933
35MP0000689_abnormal_spleen_morphology1.95747517
36MP0005408_hypopigmentation1.94341163
37MP0005174_abnormal_tail_pigmentation1.94339977
38MP0000716_abnormal_immune_system1.91494046
39MP0008057_abnormal_DNA_replication1.90950596
40MP0002405_respiratory_system_inflammati1.87738393
41MP0005387_immune_system_phenotype1.87005830
42MP0001790_abnormal_immune_system1.87005830
43MP0003172_abnormal_lysosome_physiology1.83958159
44MP0001666_abnormal_nutrient_absorption1.82797049
45MP0003186_abnormal_redox_activity1.82131161
46MP0002722_abnormal_immune_system1.80989272
47MP0002429_abnormal_blood_cell1.79312606
48MP0004957_abnormal_blastocyst_morpholog1.78480757
49MP0009379_abnormal_foot_pigmentation1.77513148
50MP0006082_CNS_inflammation1.77276894
51MP0000465_gastrointestinal_hemorrhage1.75417156
52MP0004808_abnormal_hematopoietic_stem1.69217605
53MP0006054_spinal_hemorrhage1.65959950
54MP0005075_abnormal_melanosome_morpholog1.58786219
55MP0005085_abnormal_gallbladder_physiolo1.53698997
56MP0001545_abnormal_hematopoietic_system1.41696413
57MP0005397_hematopoietic_system_phenotyp1.41696413
58MP0001845_abnormal_inflammatory_respons1.41164737
59MP0003111_abnormal_nucleus_morphology1.40035534
60MP0000015_abnormal_ear_pigmentation1.39975387
61MP0008875_abnormal_xenobiotic_pharmacok1.39760209
62MP0001873_stomach_inflammation1.39444933
63MP0010155_abnormal_intestine_physiology1.36088079
64MP0003656_abnormal_erythrocyte_physiolo1.34201596
65MP0008469_abnormal_protein_level1.33338644
66MP0000604_amyloidosis1.32761963
67MP0000703_abnormal_thymus_morphology1.32493092
68MP0000343_altered_response_to1.28886306
69MP0002095_abnormal_skin_pigmentation1.26334594
70MP0000609_abnormal_liver_physiology1.25209456
71MP0001529_abnormal_vocalization1.23735293
72MP0003123_paternal_imprinting1.22540163
73MP0002132_abnormal_respiratory_system1.21876851
74MP0002166_altered_tumor_susceptibility1.21316144
75MP0010329_abnormal_lipoprotein_level1.21267733
76MP0001533_abnormal_skeleton_physiology1.21183682
77MP0005451_abnormal_body_composition1.18695030
78MP0003866_abnormal_defecation1.18559372
79MP0008932_abnormal_embryonic_tissue1.17425350
80MP0003075_altered_response_to1.17259851
81MP0009697_abnormal_copulation1.16820935
82MP0003941_abnormal_skin_development1.15912550
83MP0004264_abnormal_extraembryonic_tissu1.11202268
84MP0003195_calcinosis1.09643642
85MP0005319_abnormal_enzyme/_coenzyme1.08415262
86MP0003300_gastrointestinal_ulcer1.07199981
87MP0000566_synostosis1.07169579
88MP0002019_abnormal_tumor_incidence1.03645779
89MP0003943_abnormal_hepatobiliary_system1.03064759
90MP0002933_joint_inflammation1.02250642
91MP0000598_abnormal_liver_morphology1.02105339
92MP0000313_abnormal_cell_death1.01959983
93MP0001915_intracranial_hemorrhage1.00480941
94MP0009764_decreased_sensitivity_to0.94971858
95MP0000858_altered_metastatic_potential0.94755905
96MP0001730_embryonic_growth_arrest0.90722723
97MP0009840_abnormal_foam_cell0.89878556
98MP0003448_altered_tumor_morphology0.89262971
99MP0004019_abnormal_vitamin_homeostasis0.89148881
100MP0000358_abnormal_cell_content/0.88917714
101MP0005584_abnormal_enzyme/coenzyme_acti0.87749014
102MP0002006_tumorigenesis0.87669145
103MP0001764_abnormal_homeostasis0.85771705
104MP0000678_abnormal_parathyroid_gland0.85654772
105MP0001663_abnormal_digestive_system0.85050464
106MP0005409_darkened_coat_color0.84463305
107MP0002277_abnormal_respiratory_mucosa0.82980006
108MP0006036_abnormal_mitochondrial_physio0.82369470
109MP0003806_abnormal_nucleotide_metabolis0.81589073
110MP0005164_abnormal_response_to0.78572758
111MP0005332_abnormal_amino_acid0.77887145
112MP0001293_anophthalmia0.77868602
113MP0003828_pulmonary_edema0.76940332
114MP0004883_abnormal_blood_vessel0.76407814
115MP0003252_abnormal_bile_duct0.75673795
116MP0000350_abnormal_cell_proliferation0.75539080
117MP0001849_ear_inflammation0.75282788
118MP0008873_increased_physiological_sensi0.75178951
119MP0009763_increased_sensitivity_to0.74866876
120MP0010307_abnormal_tumor_latency0.74159464
121MP0002938_white_spotting0.73501925
122MP0000249_abnormal_blood_vessel0.68433756
123MP0003303_peritoneal_inflammation0.68293296
124MP0006035_abnormal_mitochondrial_morpho0.67612098
125MP0003183_abnormal_peptide_metabolism0.66737467
126MP0004947_skin_inflammation0.65693357
127MP0005376_homeostasis/metabolism_phenot0.65024613
128MP0005310_abnormal_salivary_gland0.63678602
129MP0003191_abnormal_cellular_cholesterol0.63342462
130MP0001727_abnormal_embryo_implantation0.62501143
131MP0001905_abnormal_dopamine_level0.62496600
132MP0010368_abnormal_lymphatic_system0.61412231

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)5.51725032
2Deep venous thrombosis (HP:0002625)5.50996262
3Abnormality of cells of the erythroid lineage (HP:0012130)4.86204360
4Abnormal number of erythroid precursors (HP:0012131)4.78143171
5Petechiae (HP:0000967)4.23157053
6Prolonged partial thromboplastin time (HP:0003645)3.78907595
7Thrombocytosis (HP:0001894)3.76647374
8Joint hemorrhage (HP:0005261)3.74170237
9Recurrent abscess formation (HP:0002722)3.71676027
10Abnormality of the common coagulation pathway (HP:0010990)3.63024536
11Myositis (HP:0100614)3.57055284
12Reticulocytopenia (HP:0001896)3.54073343
13Aplastic anemia (HP:0001915)3.53533109
14IgM deficiency (HP:0002850)3.47201550
15Type I transferrin isoform profile (HP:0003642)3.27621056
16Recurrent gram-negative bacterial infections (HP:0005420)3.26588382
17Vacuolated lymphocytes (HP:0001922)3.19262984
18Menorrhagia (HP:0000132)3.19190887
19Recurrent bacterial skin infections (HP:0005406)3.17559775
20Hypobetalipoproteinemia (HP:0003563)3.16041888
21Chronic otitis media (HP:0000389)3.05588750
22Poor head control (HP:0002421)3.01570755
23Reduced antithrombin III activity (HP:0001976)3.00745555
24Gingival bleeding (HP:0000225)2.99687558
25Glomerulonephritis (HP:0000099)2.91545241
26Exertional dyspnea (HP:0002875)2.90915051
27Pallor (HP:0000980)2.87797461
28Abnormality of aromatic amino acid family metabolism (HP:0004338)2.83881540
29Macrocytic anemia (HP:0001972)2.81987021
303-Methylglutaconic aciduria (HP:0003535)2.78118329
31Hepatocellular necrosis (HP:0001404)2.77466372
32Abnormal protein glycosylation (HP:0012346)2.66244446
33Abnormal glycosylation (HP:0012345)2.66244446
34Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.66244446
35Abnormal protein N-linked glycosylation (HP:0012347)2.66244446
36Viral hepatitis (HP:0006562)2.62995165
37Mitochondrial inheritance (HP:0001427)2.61157247
38Agnosia (HP:0010524)2.57278729
39Complement deficiency (HP:0004431)2.54987539
40Aplasia/Hypoplasia of the sacrum (HP:0008517)2.54239387
41Hepatic necrosis (HP:0002605)2.51048023
42Abnormality of macrophages (HP:0004311)2.48259095
43Eczematoid dermatitis (HP:0000976)2.46546555
44Systemic lupus erythematosus (HP:0002725)2.45063701
45Gastrointestinal infarctions (HP:0005244)2.44255216
46Oral leukoplakia (HP:0002745)2.43406383
47Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.42397607
48Increased hepatocellular lipid droplets (HP:0006565)2.42306603
49Epistaxis (HP:0000421)2.40167667
50Orchitis (HP:0100796)2.40063557
51Purpura (HP:0000979)2.39841876
52Recurrent viral infections (HP:0004429)2.39128276
53Hepatosplenomegaly (HP:0001433)2.38892302
54Hypercholesterolemia (HP:0003124)2.38604647
55Mediastinal lymphadenopathy (HP:0100721)2.37938294
56Amyloidosis (HP:0011034)2.37849992
57Hemorrhage of the eye (HP:0011885)2.37753039
58Increased CSF lactate (HP:0002490)2.36285285
59Acute necrotizing encephalopathy (HP:0006965)2.35345448
60Hepatocellular carcinoma (HP:0001402)2.30363232
61Increased neuronal autofluorescent lipopigment (HP:0002074)2.30314469
62Abnormality of complement system (HP:0005339)2.27284114
63Increased serum pyruvate (HP:0003542)2.26477340
64Abnormality of glycolysis (HP:0004366)2.26477340
65Abnormality of the heme biosynthetic pathway (HP:0010472)2.26399124
66Renal Fanconi syndrome (HP:0001994)2.25438339
67Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.24353263
68Pancytopenia (HP:0001876)2.23555053
69Increased serum lactate (HP:0002151)2.23048710
70Panhypogammaglobulinemia (HP:0003139)2.22451781
71Abnormality of the peritoneum (HP:0002585)2.20713594
72Decreased activity of mitochondrial respiratory chain (HP:0008972)2.18490163
73Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.18490163
74B lymphocytopenia (HP:0010976)2.18335760
75Abnormality of B cell number (HP:0010975)2.18335760
76Abnormal mitochondria in muscle tissue (HP:0008316)2.18085301
77Lipid accumulation in hepatocytes (HP:0006561)2.17728417
78Interstitial pulmonary disease (HP:0006530)2.17547013
79Lymphoma (HP:0002665)2.16984497
80IgG deficiency (HP:0004315)2.16259404
81Subacute progressive viral hepatitis (HP:0006572)2.16193422
82Obstructive lung disease (HP:0006536)2.16092519
83Chronic obstructive pulmonary disease (HP:0006510)2.16092519
84Increased serum ferritin (HP:0003281)2.14905254
85Cerebral hypomyelination (HP:0006808)2.13890669
86Myocardial infarction (HP:0001658)2.13309808
87Abnormal gallbladder physiology (HP:0012438)2.13000518
88Cholecystitis (HP:0001082)2.13000518
89Basal ganglia calcification (HP:0002135)2.10612436
90Recurrent bronchitis (HP:0002837)2.09213816
91Retrobulbar optic neuritis (HP:0100654)2.09175086
92Optic neuritis (HP:0100653)2.09175086
93Recurrent skin infections (HP:0001581)2.07735855
94Hypoplasia of the thymus (HP:0000778)2.07480294
95Xanthomatosis (HP:0000991)2.06263352
96Hyperammonemia (HP:0001987)2.06077455
97Abnormality of monocarboxylic acid metabolism (HP:0010996)2.04980207
98Spastic diplegia (HP:0001264)2.04741903
99Hyperglycinemia (HP:0002154)2.03621207
100Abnormality of methionine metabolism (HP:0010901)2.00960301
101Nephroblastoma (Wilms tumor) (HP:0002667)1.99537932
102Abnormality of the prostate (HP:0008775)1.98998430
103Thyroiditis (HP:0100646)1.98418294
104Increased IgM level (HP:0003496)1.98213017
105Premature graying of hair (HP:0002216)1.98209582
106Urticaria (HP:0001025)1.97773176
107Abnormality of iron homeostasis (HP:0011031)1.97214496
108Episodic fever (HP:0001954)1.96370204
109Acute hepatic failure (HP:0006554)1.94839990
110Type 2 muscle fiber atrophy (HP:0003554)1.94211338
111Vertebral compression fractures (HP:0002953)1.93681441
112Meningitis (HP:0001287)1.93541056
113Multiple enchondromatosis (HP:0005701)1.91685553
114Vasculitis (HP:0002633)1.91249618
115Abnormality of T cell physiology (HP:0011840)1.90911862
116Severe combined immunodeficiency (HP:0004430)1.90308494
117Increased cerebral lipofuscin (HP:0011813)1.90222732
118Neutropenia (HP:0001875)1.90083786
119Small epiphyses (HP:0010585)1.89906038
120Increased intramyocellular lipid droplets (HP:0012240)1.89722075
121Acute encephalopathy (HP:0006846)1.89502610
122Cellulitis (HP:0100658)1.89448185
123Lymphopenia (HP:0001888)1.87696602
124Acanthocytosis (HP:0001927)1.86741508
125Leukopenia (HP:0001882)1.86382145
126Irregular epiphyses (HP:0010582)1.86157840
127Prolonged bleeding time (HP:0003010)1.85910553
128Respiratory difficulties (HP:0002880)1.85268694
129Severe visual impairment (HP:0001141)1.85154420
130Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.84603227
131CNS hypomyelination (HP:0003429)1.84000950
132Amaurosis fugax (HP:0100576)1.83355909
133Pancreatic islet-cell hyperplasia (HP:0004510)1.83231880
134Recurrent fungal infections (HP:0002841)1.80509820
135Rough bone trabeculation (HP:0100670)1.79473199
136Leukocytosis (HP:0001974)1.79099310
137Muscle fiber atrophy (HP:0100295)1.78805369
138Abnormality of cells of the lymphoid lineage (HP:0012140)1.78786491
139Dysostosis multiplex (HP:0000943)1.78511383
140Microvesicular hepatic steatosis (HP:0001414)1.78189923
141Lactic acidosis (HP:0003128)1.77852037
142Gastrointestinal stroma tumor (HP:0100723)1.77624663
14311 pairs of ribs (HP:0000878)1.77585627
144Abnormality of T cells (HP:0002843)1.77074049
145Abnormality of aspartate family amino acid metabolism (HP:0010899)1.76495995
146Neoplasm of the liver (HP:0002896)1.75152781
147Polygenic inheritance (HP:0010982)1.75120633
148Spastic paraparesis (HP:0002313)1.74772811
149Colitis (HP:0002583)1.74685595
150Encephalitis (HP:0002383)1.74597985
151Beaking of vertebral bodies (HP:0004568)1.74444338
152Mucopolysacchariduria (HP:0008155)1.73999948
153Urinary glycosaminoglycan excretion (HP:0003541)1.73999948
154Micronodular cirrhosis (HP:0001413)1.73924132
155Gastrointestinal inflammation (HP:0004386)1.73490844
156Thrombophlebitis (HP:0004418)1.72986366
157Gingivitis (HP:0000230)1.72518169
158Anorexia (HP:0002039)1.71153137
159Abnormal platelet volume (HP:0011876)1.70173827
160Abnormality of carpal bone ossification (HP:0006257)1.69925825
161Embryonal renal neoplasm (HP:0011794)1.69732411
162Abnormal delayed hypersensitivity skin test (HP:0002963)1.69623355
163Pustule (HP:0200039)1.68382233
164Hypolipoproteinemia (HP:0010981)1.67522480
165Papillary thyroid carcinoma (HP:0002895)1.67199327
166Ragged-red muscle fibers (HP:0003200)1.64600762
167Peritonitis (HP:0002586)1.62610989
168Epidermoid cyst (HP:0200040)1.61884471

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.68055113
2VRK23.26344566
3SMG13.02258464
4BUB12.91891648
5MAP4K12.52078927
6WEE12.44974497
7KIT2.38424811
8NME22.30265417
9BLK2.24645984
10TGFBR12.24037458
11EIF2AK32.20365988
12FGFR42.12903953
13EIF2AK12.11687771
14ACVR1B1.95733628
15BTK1.95457703
16IRAK41.94234541
17TEC1.92986060
18MAP3K121.87556399
19VRK11.86810982
20CDK191.86806674
21TNIK1.85641903
22PIM21.83068854
23CSF1R1.82441223
24FGR1.70335847
25KDR1.70078266
26ZAP701.67857816
27TBK11.58620093
28TGFBR21.57128907
29CCNB11.54391959
30BMPR1B1.50579956
31SYK1.41462891
32TXK1.41405310
33TESK21.40927834
34NEK11.38432779
35ERN11.36926208
36DYRK31.36353111
37TSSK61.30889009
38EPHA21.29777864
39FLT31.29407974
40FGFR31.25645588
41PBK1.23473734
42CSK1.23139605
43TYK21.23102997
44SIK31.22838003
45CLK11.20674480
46MKNK11.19255725
47JAK31.18063804
48LYN1.14716187
49CDC71.13140089
50TAF11.12360739
51DYRK1B1.11362239
52IKBKB1.09277817
53MAP3K31.05008002
54PASK1.05001397
55MUSK1.04246951
56ADRBK21.04162408
57MST41.04009932
58PAK41.03283315
59YES11.02877274
60CDK61.02194671
61CDK80.99111439
62ATR0.97775786
63GRK70.97193334
64MATK0.94031676
65EIF2AK20.92140819
66STK100.91819608
67MYLK0.90703224
68LCK0.88743585
69NEK20.87341331
70TLK10.86262251
71BRSK20.84574123
72PDK20.84429752
73FES0.83844002
74CDK70.83462980
75FGFR10.82537309
76TTK0.82219284
77TESK10.81512610
78IKBKE0.80687903
79PLK30.80665479
80RPS6KB20.79671823
81ZAK0.78548210
82NEK90.78177644
83MAPKAPK30.77284828
84PKN20.75844150
85RPS6KA40.71371148
86MAP3K110.71163433
87ICK0.71056849
88TNK20.70815366
89TIE10.70709749
90BMX0.70626592
91ITK0.70334473
92MAPKAPK50.69111153
93PTK60.68585024
94ILK0.67783431
95AURKB0.66850761
96NUAK10.66495968
97CDK90.65964866
98RIPK40.65891767
99MAP3K50.65046330
100NLK0.61486276
101SCYL20.61042157
102MAP3K140.60529082
103EEF2K0.60381687
104HCK0.59370105
105PDPK10.58676802
106DAPK10.58627080
107MAP2K30.57729408
108GRK60.57453508
109SRPK10.57376720
110ALK0.57333169
111IRAK20.56561877
112BRSK10.56426550
113MAP3K70.55714638
114DYRK20.54453868
115CDK40.53945443
116MAP3K80.51415743
117LRRK20.51185963
118TAOK20.49726657
119MAP2K20.49700293
120MELK0.49253337
121PAK10.48991937
122PLK10.48590978
123CSNK2A10.48472063
124MAPKAPK20.48382965
125NME10.48360299
126IRAK30.47572238
127MAPK40.46742223
128AURKA0.46636892
129LIMK10.45719342
130JAK20.43211231
131TRPM70.41444925
132PRKD20.40759427
133PIM10.40554740
134BCKDK0.40412462
135CDK120.39465784
136PDK10.39094029
137EPHB10.38403392
138PLK40.37660500
139CSNK2A20.36633859
140TRIB30.35230369
141BRD40.34487601

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.38458071
2DNA replication_Homo sapiens_hsa030304.21789884
3Proteasome_Homo sapiens_hsa030503.77030304
4Mismatch repair_Homo sapiens_hsa034302.88569253
5RNA polymerase_Homo sapiens_hsa030202.81037476
6Base excision repair_Homo sapiens_hsa034102.63524761
7Complement and coagulation cascades_Homo sapiens_hsa046102.54320606
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.45636815
9Spliceosome_Homo sapiens_hsa030402.37797593
10Pyrimidine metabolism_Homo sapiens_hsa002402.26825560
11Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.18358212
12Protein export_Homo sapiens_hsa030602.10657277
13Non-homologous end-joining_Homo sapiens_hsa034502.06980041
14Homologous recombination_Homo sapiens_hsa034402.00180652
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.95605361
16Nucleotide excision repair_Homo sapiens_hsa034201.93425640
17Primary immunodeficiency_Homo sapiens_hsa053401.87213010
18Other glycan degradation_Homo sapiens_hsa005111.84350209
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.74697173
20Carbon metabolism_Homo sapiens_hsa012001.61780024
21Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.53477780
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.52927461
23Parkinsons disease_Homo sapiens_hsa050121.49780541
24Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.49063450
25Antigen processing and presentation_Homo sapiens_hsa046121.45448703
26One carbon pool by folate_Homo sapiens_hsa006701.45215444
27Oxidative phosphorylation_Homo sapiens_hsa001901.42522841
28Legionellosis_Homo sapiens_hsa051341.37123205
29RNA transport_Homo sapiens_hsa030131.34879259
30Fatty acid degradation_Homo sapiens_hsa000711.34167359
31Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.29737199
32Leishmaniasis_Homo sapiens_hsa051401.28374492
33Cell cycle_Homo sapiens_hsa041101.26676128
34Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.23050649
35Herpes simplex infection_Homo sapiens_hsa051681.21583269
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.19986061
37NF-kappa B signaling pathway_Homo sapiens_hsa040641.19624304
38Allograft rejection_Homo sapiens_hsa053301.19251849
39Pentose phosphate pathway_Homo sapiens_hsa000301.19062302
40Intestinal immune network for IgA production_Homo sapiens_hsa046721.17868260
41Malaria_Homo sapiens_hsa051441.17648119
42Measles_Homo sapiens_hsa051621.17378407
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.17007524
44Asthma_Homo sapiens_hsa053101.13304637
45Type I diabetes mellitus_Homo sapiens_hsa049401.09236822
46Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.09199444
47Pentose and glucuronate interconversions_Homo sapiens_hsa000401.08377719
48N-Glycan biosynthesis_Homo sapiens_hsa005101.07371022
49Phenylalanine metabolism_Homo sapiens_hsa003601.05617520
50Hematopoietic cell lineage_Homo sapiens_hsa046401.04928766
51Epstein-Barr virus infection_Homo sapiens_hsa051691.04171243
52Fanconi anemia pathway_Homo sapiens_hsa034601.03956945
53RNA degradation_Homo sapiens_hsa030181.03938033
54Vitamin B6 metabolism_Homo sapiens_hsa007501.03330573
55* Purine metabolism_Homo sapiens_hsa002301.02890504
56Glycosaminoglycan degradation_Homo sapiens_hsa005311.02328646
57Basal transcription factors_Homo sapiens_hsa030220.99844062
58Histidine metabolism_Homo sapiens_hsa003400.98796052
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.96397156
60Huntingtons disease_Homo sapiens_hsa050160.95966549
61RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.95695244
62Pertussis_Homo sapiens_hsa051330.95604951
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.94176355
64Peroxisome_Homo sapiens_hsa041460.93902771
65Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.93428052
66Pyruvate metabolism_Homo sapiens_hsa006200.93284196
67Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.92379108
68Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.91799890
69Shigellosis_Homo sapiens_hsa051310.91741679
70Fatty acid metabolism_Homo sapiens_hsa012120.90937861
71Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.86379181
72Tyrosine metabolism_Homo sapiens_hsa003500.85630402
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.84613923
74Toll-like receptor signaling pathway_Homo sapiens_hsa046200.84461095
75Systemic lupus erythematosus_Homo sapiens_hsa053220.84399241
76Vitamin digestion and absorption_Homo sapiens_hsa049770.82642665
77Staphylococcus aureus infection_Homo sapiens_hsa051500.81156388
78Lysosome_Homo sapiens_hsa041420.80775037
79Propanoate metabolism_Homo sapiens_hsa006400.80583880
80Steroid biosynthesis_Homo sapiens_hsa001000.79297836
81Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.78615303
82Fat digestion and absorption_Homo sapiens_hsa049750.78537232
83Starch and sucrose metabolism_Homo sapiens_hsa005000.77232686
84Alzheimers disease_Homo sapiens_hsa050100.76231205
85Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.74331277
86Autoimmune thyroid disease_Homo sapiens_hsa053200.72838967
87B cell receptor signaling pathway_Homo sapiens_hsa046620.70257166
88p53 signaling pathway_Homo sapiens_hsa041150.69311176
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.69032884
90Arginine biosynthesis_Homo sapiens_hsa002200.67690516
91Primary bile acid biosynthesis_Homo sapiens_hsa001200.67107951
92Influenza A_Homo sapiens_hsa051640.66147300
93Apoptosis_Homo sapiens_hsa042100.65381935
94Phagosome_Homo sapiens_hsa041450.65364316
95Osteoclast differentiation_Homo sapiens_hsa043800.65068272
96Galactose metabolism_Homo sapiens_hsa000520.65055489
97Folate biosynthesis_Homo sapiens_hsa007900.64566329
98Sulfur relay system_Homo sapiens_hsa041220.63347176
99Arginine and proline metabolism_Homo sapiens_hsa003300.62834699
100Glutathione metabolism_Homo sapiens_hsa004800.62187223
101Salmonella infection_Homo sapiens_hsa051320.60333209
102PPAR signaling pathway_Homo sapiens_hsa033200.60156500
103NOD-like receptor signaling pathway_Homo sapiens_hsa046210.59728775
104Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.59202108
105SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57891616
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57756706
107Graft-versus-host disease_Homo sapiens_hsa053320.57108649
108Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.56620929
109Selenocompound metabolism_Homo sapiens_hsa004500.55226196
110Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.54413027
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54251383
112Chemical carcinogenesis_Homo sapiens_hsa052040.54227305
113Toxoplasmosis_Homo sapiens_hsa051450.53056692
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52173147
115Hepatitis B_Homo sapiens_hsa051610.51392256
116Cysteine and methionine metabolism_Homo sapiens_hsa002700.50569848
117Drug metabolism - other enzymes_Homo sapiens_hsa009830.50360447
118Tuberculosis_Homo sapiens_hsa051520.49313253
119Viral carcinogenesis_Homo sapiens_hsa052030.49192524
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48798971
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.47401980
122Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47285139
123Cyanoamino acid metabolism_Homo sapiens_hsa004600.47284480
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46171832
125Fatty acid elongation_Homo sapiens_hsa000620.45769096
126Renin-angiotensin system_Homo sapiens_hsa046140.45306373
127Arachidonic acid metabolism_Homo sapiens_hsa005900.45119012
128Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.44363878
129Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.43095404
130Rheumatoid arthritis_Homo sapiens_hsa053230.40941039
131Viral myocarditis_Homo sapiens_hsa054160.40170573
132HTLV-I infection_Homo sapiens_hsa051660.40019382
133Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.39224918
134Biosynthesis of amino acids_Homo sapiens_hsa012300.38221148
135Jak-STAT signaling pathway_Homo sapiens_hsa046300.36946938
136Fructose and mannose metabolism_Homo sapiens_hsa000510.36580198
137Metabolic pathways_Homo sapiens_hsa011000.35807655

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »