GNAI2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.55177043
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.55177043
3detection of other organism (GO:0098543)4.35564215
4antigen processing and presentation of endogenous antigen (GO:0019883)4.34081568
5detection of bacterium (GO:0016045)4.19499433
6positive regulation by symbiont of host defense response (GO:0052509)3.83839430
7modulation by symbiont of host defense response (GO:0052031)3.83839430
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.83839430
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.83839430
10positive regulation by organism of defense response of other organism involved in symbiotic interact3.83839430
11modulation by symbiont of host immune response (GO:0052553)3.83839430
12positive regulation of gamma-delta T cell activation (GO:0046645)3.77739147
13Arp2/3 complex-mediated actin nucleation (GO:0034314)3.71446667
14positive regulation of histone deacetylation (GO:0031065)3.69918837
15detection of external biotic stimulus (GO:0098581)3.69802512
16growth hormone receptor signaling pathway (GO:0060396)3.52022633
17regulation of mast cell degranulation (GO:0043304)3.46200102
18detection of molecule of bacterial origin (GO:0032490)3.45717881
19cellular extravasation (GO:0045123)3.44406611
20regulation of leukocyte degranulation (GO:0043300)3.42054370
21negative regulation of cell killing (GO:0031342)3.37600354
22negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.37600354
23negative regulation of phagocytosis (GO:0050765)3.34013386
24JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.32862327
25regulation of myeloid leukocyte mediated immunity (GO:0002886)3.32706506
26response to laminar fluid shear stress (GO:0034616)3.31712218
27regulation of B cell receptor signaling pathway (GO:0050855)3.30844363
28regulation of gamma-delta T cell differentiation (GO:0045586)3.30321838
29positive regulation of lamellipodium assembly (GO:0010592)3.27829676
30detection of biotic stimulus (GO:0009595)3.27065517
31regulation of interferon-beta biosynthetic process (GO:0045357)3.24480220
32positive thymic T cell selection (GO:0045059)3.20906684
33morphogenesis of an endothelium (GO:0003159)3.16243900
34endothelial tube morphogenesis (GO:0061154)3.16243900
35negative regulation of lymphocyte mediated immunity (GO:0002707)3.15708376
36leukocyte aggregation (GO:0070486)3.14251593
37positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.12570368
38negative regulation of leukocyte mediated immunity (GO:0002704)3.11356974
39regulation of mast cell activation involved in immune response (GO:0033006)3.10833426
40positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.06371535
41regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04850796
42regulation of gamma-delta T cell activation (GO:0046643)3.02822228
43cellular response to growth hormone stimulus (GO:0071378)3.02528373
44regulation of T cell tolerance induction (GO:0002664)3.02120249
45lipopolysaccharide-mediated signaling pathway (GO:0031663)2.99730836
46regulation of T-helper 2 cell differentiation (GO:0045628)2.96599487
47positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.96221802
48apoptotic cell clearance (GO:0043277)2.94958893
49macrophage activation (GO:0042116)2.94861179
50antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.94351834
51myeloid cell activation involved in immune response (GO:0002275)2.93306033
52germinal center formation (GO:0002467)2.90552288
53positive regulation of lamellipodium organization (GO:1902745)2.90433752
54immunoglobulin mediated immune response (GO:0016064)2.88141754
55type I interferon signaling pathway (GO:0060337)2.87064811
56cellular response to type I interferon (GO:0071357)2.87064811
57response to type I interferon (GO:0034340)2.85413322
58negative regulation of erythrocyte differentiation (GO:0045647)2.85188821
59tolerance induction (GO:0002507)2.85119154
60regulation of tolerance induction (GO:0002643)2.84301185
61regulation of interleukin-12 biosynthetic process (GO:0045075)2.84271364
62positive regulation of mast cell activation (GO:0033005)2.83306514
63regulation of regulated secretory pathway (GO:1903305)2.82386795
64cortical actin cytoskeleton organization (GO:0030866)2.80833568
65positive regulation of protein deacetylation (GO:0090312)2.76729095
66microglial cell activation (GO:0001774)2.76172045
67negative regulation of T cell mediated immunity (GO:0002710)2.75419335
68leukocyte migration involved in inflammatory response (GO:0002523)2.75398051
69response to interleukin-15 (GO:0070672)2.74495796
70antigen processing and presentation via MHC class Ib (GO:0002475)2.72194735
71negative thymic T cell selection (GO:0045060)2.70269850
72interferon-gamma-mediated signaling pathway (GO:0060333)2.69517572
73actin nucleation (GO:0045010)2.69152569
74positive regulation of cellular amide metabolic process (GO:0034250)2.68620652
75negative regulation of granulocyte differentiation (GO:0030853)2.68547087
76regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.67949391
77negative regulation of cytokine production involved in immune response (GO:0002719)2.67178339
78positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.67135758
79germ cell migration (GO:0008354)2.66608953
80negative regulation of type 2 immune response (GO:0002829)2.65894997
81negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.65482675
82macrophage activation involved in immune response (GO:0002281)2.65177879
83vascular endothelial growth factor signaling pathway (GO:0038084)2.64178286
84regulation of mast cell activation (GO:0033003)2.64066911
85protein localization to endosome (GO:0036010)2.63770406
86respiratory burst (GO:0045730)2.63044695
87response to muramyl dipeptide (GO:0032495)2.62878900
88leukocyte cell-cell adhesion (GO:0007159)2.61434893
89NIK/NF-kappaB signaling (GO:0038061)2.60039283
90positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.59122274
91negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.58499105
92pinocytosis (GO:0006907)2.58265558
93positive regulation of mast cell activation involved in immune response (GO:0033008)2.56620387
94positive regulation of mast cell degranulation (GO:0043306)2.56620387
95negative regulation of interleukin-6 production (GO:0032715)2.56548775
96B cell receptor signaling pathway (GO:0050853)2.56141301
97T cell selection (GO:0045058)2.56075187
98response to fluid shear stress (GO:0034405)2.55618066
99thymic T cell selection (GO:0045061)2.55593699
100regulation of antigen processing and presentation (GO:0002577)2.55429692
101neutrophil activation involved in immune response (GO:0002283)2.55246907
102negative regulation of innate immune response (GO:0045824)2.53961252
103response to peptidoglycan (GO:0032494)2.53734828
104negative T cell selection (GO:0043383)2.53287210
105defense response to protozoan (GO:0042832)2.53121785
106negative regulation of fatty acid transport (GO:2000192)2.51877293
107positive regulation of B cell differentiation (GO:0045579)2.51510794
108regulation of B cell differentiation (GO:0045577)2.50501705
109positive regulation of leukocyte degranulation (GO:0043302)2.49956323
110barbed-end actin filament capping (GO:0051016)2.49874373
111negative regulation of interleukin-12 production (GO:0032695)2.49102119
112stress fiber assembly (GO:0043149)2.47243682
113endodermal cell differentiation (GO:0035987)2.46842890
114T cell apoptotic process (GO:0070231)2.46729286
115response to host (GO:0075136)2.46647727
116response to host defenses (GO:0052200)2.46647727
117response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.46647727
118cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.46082904
119natural killer cell differentiation (GO:0001779)2.45990481
120response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.45551093
121response to host immune response (GO:0052572)2.45551093
122regulation of macrophage cytokine production (GO:0010935)2.43776998
123substrate-dependent cell migration (GO:0006929)2.40399433
124regulation of protein heterodimerization activity (GO:0043497)2.40268764
125integrin-mediated signaling pathway (GO:0007229)2.39138865
126mannose metabolic process (GO:0006013)2.38998296
127establishment of endothelial barrier (GO:0061028)2.38391542
128basement membrane organization (GO:0071711)2.37462289
129hyaluronan catabolic process (GO:0030214)2.34589890
130response to fungus (GO:0009620)2.34515368
131regulation of type I interferon-mediated signaling pathway (GO:0060338)2.32723830
132cortical cytoskeleton organization (GO:0030865)2.32621133
133angiogenesis involved in wound healing (GO:0060055)2.32552131
134B cell mediated immunity (GO:0019724)2.32211424
135neutrophil activation (GO:0042119)2.31933423
136positive regulation of interferon-alpha production (GO:0032727)2.31461999
137apoptotic process involved in morphogenesis (GO:0060561)2.29517804
138negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.28514524
139sequestering of metal ion (GO:0051238)2.28193657
140positive regulation of antigen processing and presentation (GO:0002579)2.28192281
141regulation of cholesterol storage (GO:0010885)2.28010560
142granulocyte activation (GO:0036230)2.27465857
143macrophage differentiation (GO:0030225)2.26879212
144positive regulation of blood vessel endothelial cell migration (GO:0043536)2.25888697
145hepatocyte apoptotic process (GO:0097284)2.25665399
146regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.24336406
1473-UTR-mediated mRNA stabilization (GO:0070935)2.23343145
148mRNA stabilization (GO:0048255)2.22028220
149RNA stabilization (GO:0043489)2.22028220
150positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.20754905
151regulation of interferon-alpha production (GO:0032647)2.20358586

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human3.96112922
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.63678545
3MYC_22102868_ChIP-Seq_BL_Human3.25040575
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.97226480
5* VDR_21846776_ChIP-Seq_THP-1_Human2.96459303
6BP1_19119308_ChIP-ChIP_Hs578T_Human2.71517546
7IRF8_22096565_ChIP-ChIP_GC-B_Human2.62461033
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.60329106
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.54211038
10IRF8_21731497_ChIP-ChIP_J774_Mouse2.53964100
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.53576453
12E2F7_22180533_ChIP-Seq_HELA_Human2.49016308
13* TCF7_22412390_ChIP-Seq_EML_Mouse2.44537154
14* ELK3_25401928_ChIP-Seq_HUVEC_Human2.40802714
15* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.37034274
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.36383709
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.31832854
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.30782735
19KDM2B_26808549_Chip-Seq_SUP-B15_Human2.29532637
20NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.28405809
21* KDM2B_26808549_Chip-Seq_DND41_Human2.26767349
22* MAF_26560356_Chip-Seq_TH1_Human2.25549039
23* IRF8_27001747_Chip-Seq_BMDM_Mouse2.24471579
24FOXM1_23109430_ChIP-Seq_U2OS_Human2.22205090
25* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.12855611
26* VDR_24763502_ChIP-Seq_THP-1_Human2.12833136
27BRD4_27068464_Chip-Seq_AML-cells_Mouse2.12689556
28* UTX_26944678_Chip-Seq_JUKART_Human2.02766926
29KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.93948816
30SCL_19346495_ChIP-Seq_HPC-7_Human1.91839410
31* SPI1_23127762_ChIP-Seq_K562_Human1.82096935
32MYB_26560356_Chip-Seq_TH2_Human1.78316759
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.76234225
34E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.75739774
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.75332470
36SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.73267169
37* RUNX1_22412390_ChIP-Seq_EML_Mouse1.71780294
38* LXR_22292898_ChIP-Seq_THP-1_Human1.69386223
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.65812114
40* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.64327323
41* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.63265672
42TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62782188
43KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.61293704
44* SPI1_23547873_ChIP-Seq_NB4_Human1.60326659
45TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.59398634
46CLOCK_20551151_ChIP-Seq_293T_Human1.59253276
47RUNX_20019798_ChIP-Seq_JUKART_Human1.56588491
48MYB_26560356_Chip-Seq_TH1_Human1.54281960
49* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.53985785
50RACK7_27058665_Chip-Seq_MCF-7_Human1.50441162
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.45959985
52* KDM2B_26808549_Chip-Seq_JURKAT_Human1.44587988
53* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.41585484
54IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.41026910
55TRIM28_21343339_ChIP-Seq_HEK293_Human1.38108545
56P300_27058665_Chip-Seq_ZR-75-30cells_Human1.37087098
57* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.36186404
58* MAF_26560356_Chip-Seq_TH2_Human1.35385095
59PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.35240200
60IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.34369404
61NCOR1_26117541_ChIP-Seq_K562_Human1.34020438
62KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.31081962
63* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.30994576
64LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.28086613
65* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.24850889
66SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.24727414
67VDR_24787735_ChIP-Seq_THP-1_Human1.24680601
68GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.22101520
69THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.21917794
70STAT6_21828071_ChIP-Seq_BEAS2B_Human1.19253834
71FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.18072305
72GATA1_22383799_ChIP-Seq_G1ME_Mouse1.17328316
73* SA1_27219007_Chip-Seq_ERYTHROID_Human1.16552666
74ATF3_27146783_Chip-Seq_COLON_Human1.16091379
75IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15691932
76EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13610031
77GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.13226387
78SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.12547836
79PU_27001747_Chip-Seq_BMDM_Mouse1.12122240
80NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.11637067
81TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.11535642
82ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.11112043
83* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10484229
84VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.09856267
85KDM2B_26808549_Chip-Seq_K562_Human1.09698128
86GATA1_19941826_ChIP-Seq_K562_Human1.09460675
87* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.08717814
88ZFP281_18757296_ChIP-ChIP_E14_Mouse1.08332997
89GATA2_21666600_ChIP-Seq_HMVEC_Human1.08302074
90Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.07575227
91MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.06262963
92GATA3_27048872_Chip-Seq_THYMUS_Human1.06257899
93* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05582743
94* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.05181479
95CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.04914731
96CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04488963
97SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03866436
98CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03063337
99SMAD_19615063_ChIP-ChIP_OVARY_Human1.02978703
100GATA2_22383799_ChIP-Seq_G1ME_Mouse1.02852813
101PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02758093
102* BCL6_27268052_Chip-Seq_Bcells_Human1.02587379
103ELF1_20517297_ChIP-Seq_JURKAT_Human1.02585266
104* BCOR_27268052_Chip-Seq_Bcells_Human1.00870220
105ZFP281_27345836_Chip-Seq_ESCs_Mouse1.00846037
106* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00433013
107HIF1A_21447827_ChIP-Seq_MCF-7_Human1.00309308
108* P68_20966046_ChIP-Seq_HELA_Human1.00261880
109LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.99619885
110WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.99514305
111UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.98045823
112GATA1_19941827_ChIP-Seq_MEL_Mouse0.96957751
113SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96285340
114CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95450612
115TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94276845
116SMC1_22415368_ChIP-Seq_MEFs_Mouse0.94262429
117CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92369371
118TP53_22127205_ChIP-Seq_IMR90_Human0.91709324
119UBF1/2_26484160_Chip-Seq_HMECs_Human0.90930566
120FOXO3_23340844_ChIP-Seq_DLD1_Human0.90477656
121TFEB_21752829_ChIP-Seq_HELA_Human0.90125343
122PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.89928767
123ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.89842265

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0003303_peritoneal_inflammation2.89755234
2MP0009278_abnormal_bone_marrow2.81477117
3MP0003705_abnormal_hypodermis_morpholog2.80942118
4MP0003436_decreased_susceptibility_to2.59697205
5MP0003566_abnormal_cell_adhesion2.40453383
6* MP0003300_gastrointestinal_ulcer2.35314051
7MP0005076_abnormal_cell_differentiation2.34345291
8MP0001835_abnormal_antigen_presentation2.26922402
9MP0008438_abnormal_cutaneous_collagen2.18478003
10MP0010352_gastrointestinal_tract_polyps2.13987552
11MP0008260_abnormal_autophagy1.98785404
12MP0005058_abnormal_lysosome_morphology1.98549443
13MP0003279_aneurysm1.96494192
14MP0004808_abnormal_hematopoietic_stem1.87133811
15MP0005000_abnormal_immune_tolerance1.85218001
16MP0004510_myositis1.85089707
17* MP0002419_abnormal_innate_immunity1.83009642
18* MP0002452_abnormal_antigen_presenting1.82745852
19* MP0001790_abnormal_immune_system1.80097800
20* MP0005387_immune_system_phenotype1.80097800
21* MP0001800_abnormal_humoral_immune1.77814300
22* MP0000685_abnormal_immune_system1.75779094
23MP0002877_abnormal_melanocyte_morpholog1.68361293
24MP0002405_respiratory_system_inflammati1.67461353
25MP0005464_abnormal_platelet_physiology1.66882335
26* MP0002420_abnormal_adaptive_immunity1.66155542
27* MP0005025_abnormal_response_to1.66044871
28MP0006054_spinal_hemorrhage1.65791832
29MP0005451_abnormal_body_composition1.65677055
30* MP0001819_abnormal_immune_cell1.65566841
31MP0001533_abnormal_skeleton_physiology1.62452629
32MP0001545_abnormal_hematopoietic_system1.60485810
33MP0005397_hematopoietic_system_phenotyp1.60485810
34MP0002396_abnormal_hematopoietic_system1.60471633
35MP0003448_altered_tumor_morphology1.57881142
36MP0010368_abnormal_lymphatic_system1.56152652
37* MP0002723_abnormal_immune_serum1.55173121
38MP0009785_altered_susceptibility_to1.51302530
39MP0006082_CNS_inflammation1.50962178
40MP0002148_abnormal_hypersensitivity_rea1.49337272
41MP0005023_abnormal_wound_healing1.49153308
42MP0005671_abnormal_response_to1.48978900
43MP0001879_abnormal_lymphatic_vessel1.48256181
44MP0000858_altered_metastatic_potential1.47425492
45MP0000465_gastrointestinal_hemorrhage1.47114341
46MP0004947_skin_inflammation1.46625554
47* MP0002398_abnormal_bone_marrow1.46462103
48MP0002933_joint_inflammation1.45527063
49MP0002166_altered_tumor_susceptibility1.45459837
50MP0009333_abnormal_splenocyte_physiolog1.45066662
51MP0001958_emphysema1.44931884
52MP0005167_abnormal_blood-brain_barrier1.41914065
53MP0003091_abnormal_cell_migration1.37559812
54MP0004272_abnormal_basement_membrane1.35525339
55MP0003724_increased_susceptibility_to1.34635736
56* MP0000716_abnormal_immune_system1.34364364
57MP0003172_abnormal_lysosome_physiology1.34360592
58MP0000343_altered_response_to1.33172395
59MP0003690_abnormal_glial_cell1.32803049
60MP0010307_abnormal_tumor_latency1.31192425
61MP0002138_abnormal_hepatobiliary_system1.30311627
62MP0000604_amyloidosis1.29084731
63MP0000733_abnormal_muscle_development1.29039769
64* MP0010155_abnormal_intestine_physiology1.28507596
65MP0004858_abnormal_nervous_system1.26896927
66MP0004185_abnormal_adipocyte_glucose1.26133041
67MP0004883_abnormal_blood_vessel1.25131491
68MP0002722_abnormal_immune_system1.24643942
69MP0003763_abnormal_thymus_physiology1.23990315
70MP0000689_abnormal_spleen_morphology1.22435499
71MP0000767_abnormal_smooth_muscle1.22280128
72MP0001851_eye_inflammation1.21641027
73MP0009764_decreased_sensitivity_to1.18419264
74* MP0001845_abnormal_inflammatory_respons1.18330414
75* MP0002429_abnormal_blood_cell1.17978613
76MP0001853_heart_inflammation1.15881166
77MP0003191_abnormal_cellular_cholesterol1.14478205
78MP0005257_abnormal_intraocular_pressure1.13531177
79MP0001849_ear_inflammation1.12140816
80MP0005164_abnormal_response_to1.10924890
81MP0003045_fibrosis1.08404995
82MP0002998_abnormal_bone_remodeling1.05896221
83MP0002132_abnormal_respiratory_system1.04356486
84* MP0000703_abnormal_thymus_morphology1.04040961
85MP0003329_amyloid_beta_deposits1.02332198
86MP0005390_skeleton_phenotype1.01335601
87MP0005623_abnormal_meninges_morphology1.00046081
88MP0002006_tumorigenesis0.99997839
89MP0009840_abnormal_foam_cell0.99539166
90MP0001915_intracranial_hemorrhage0.99285483
91MP0003453_abnormal_keratinocyte_physiol0.96765040
92MP0003183_abnormal_peptide_metabolism0.94392474
93MP0008961_abnormal_basal_metabolism0.91233397
94MP0000249_abnormal_blood_vessel0.90795711
95MP0003075_altered_response_to0.90588429
96MP0001873_stomach_inflammation0.90581971
97* MP0000490_abnormal_crypts_of0.89103096
98MP0002925_abnormal_cardiovascular_devel0.88569314
99MP0005409_darkened_coat_color0.88482341
100MP0001542_abnormal_bone_strength0.87929725
101MP0005275_abnormal_skin_tensile0.87064674
102MP0008004_abnormal_stomach_pH0.86822240
103MP0010630_abnormal_cardiac_muscle0.85052788
104MP0004381_abnormal_hair_follicle0.84014047
105MP0003795_abnormal_bone_structure0.81217089
106* MP0003828_pulmonary_edema0.80101323
107MP0001614_abnormal_blood_vessel0.79711076
108MP0002128_abnormal_blood_circulation0.79503039
109MP0005310_abnormal_salivary_gland0.78891190
110* MP0003866_abnormal_defecation0.77512687
111* MP0008469_abnormal_protein_level0.72652465
112MP0000920_abnormal_myelination0.72184647
113MP0005375_adipose_tissue_phenotype0.71878062
114MP0002086_abnormal_extraembryonic_tissu0.69457444
115* MP0009763_increased_sensitivity_to0.68541984
116MP0005166_decreased_susceptibility_to0.65577531
117* MP0002019_abnormal_tumor_incidence0.65318361
118* MP0001663_abnormal_digestive_system0.62989933
119MP0005165_increased_susceptibility_to0.62332812

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)4.22138045
2Cerebral aneurysm (HP:0004944)3.79773531
3Recurrent abscess formation (HP:0002722)3.76097608
4Cellulitis (HP:0100658)3.16009001
5Protrusio acetabuli (HP:0003179)3.15957752
6Recurrent bacterial skin infections (HP:0005406)3.12869989
7Hematochezia (HP:0002573)3.11775058
8Spontaneous hematomas (HP:0007420)3.10810342
9Optic neuritis (HP:0100653)3.00090822
10Retrobulbar optic neuritis (HP:0100654)3.00090822
11Increased cerebral lipofuscin (HP:0011813)2.90400769
12Stomatitis (HP:0010280)2.83202664
13Dysostosis multiplex (HP:0000943)2.82557318
14Interstitial pulmonary disease (HP:0006530)2.76594136
15Increased density of long bones (HP:0006392)2.73259133
16Shallow orbits (HP:0000586)2.70541309
17Abnormality of the nasal mucosa (HP:0000433)2.68850249
18Gastrointestinal infarctions (HP:0005244)2.65064814
19Amyloidosis (HP:0011034)2.64245571
20Recurrent fungal infections (HP:0002841)2.59474125
21Recurrent gram-negative bacterial infections (HP:0005420)2.59457192
22Prolonged bleeding time (HP:0003010)2.57412851
23Mucopolysacchariduria (HP:0008155)2.54625525
24Urinary glycosaminoglycan excretion (HP:0003541)2.54625525
25Premature rupture of membranes (HP:0001788)2.52665820
26Abnormality of macrophages (HP:0004311)2.51934364
27Urticaria (HP:0001025)2.48301836
28Hyperacusis (HP:0010780)2.45809767
29Peritonitis (HP:0002586)2.42326112
30Recurrent cutaneous fungal infections (HP:0011370)2.41802552
31Chronic mucocutaneous candidiasis (HP:0002728)2.41802552
32Elevated erythrocyte sedimentation rate (HP:0003565)2.41742183
33Aortic aneurysm (HP:0004942)2.41208340
34Vasculitis (HP:0002633)2.39437026
35Epistaxis (HP:0000421)2.37929793
36Myositis (HP:0100614)2.37652250
37Chronic otitis media (HP:0000389)2.36986795
38Obstructive lung disease (HP:0006536)2.36554769
39Chronic obstructive pulmonary disease (HP:0006510)2.36554769
40Loss of speech (HP:0002371)2.35503260
41Recurrent viral infections (HP:0004429)2.33594412
42Nasal polyposis (HP:0100582)2.31561096
43Purpura (HP:0000979)2.30894996
44Abnormality of mucopolysaccharide metabolism (HP:0011020)2.28363671
45Abnormality of polysaccharide metabolism (HP:0011012)2.28363671
46Abnormality of glycosaminoglycan metabolism (HP:0004371)2.28363671
47Mitral valve prolapse (HP:0001634)2.28265278
48Increased neuronal autofluorescent lipopigment (HP:0002074)2.26896291
49Gastrointestinal inflammation (HP:0004386)2.26387658
50Pulmonary infiltrates (HP:0002113)2.24728260
51Aortic dissection (HP:0002647)2.23509567
52Ankle contracture (HP:0006466)2.22317951
53Vacuolated lymphocytes (HP:0001922)2.22205141
54Cervical subluxation (HP:0003308)2.22110337
55Hemoptysis (HP:0002105)2.20527288
56Mediastinal lymphadenopathy (HP:0100721)2.19601219
57Inflammation of the large intestine (HP:0002037)2.19432035
58Encephalitis (HP:0002383)2.15689152
59Petechiae (HP:0000967)2.15207856
60Keratoconjunctivitis sicca (HP:0001097)2.14916538
61Dilatation of the ascending aorta (HP:0005111)2.11668022
62Thin bony cortex (HP:0002753)2.11209599
63Abnormal delayed hypersensitivity skin test (HP:0002963)2.07819746
64Aneurysm (HP:0002617)2.06474070
65Osteolytic defects of the hand bones (HP:0009699)2.05120509
66Osteolytic defects of the phalanges of the hand (HP:0009771)2.05120509
67Disproportionate tall stature (HP:0001519)2.03760017
68Polygenic inheritance (HP:0010982)2.03724207
69Ulnar bowing (HP:0003031)2.03644394
70Gingival bleeding (HP:0000225)2.03097537
71Colitis (HP:0002583)2.02358215
72Bicuspid aortic valve (HP:0001647)2.01869391
73Genu recurvatum (HP:0002816)2.01828890
74Gingivitis (HP:0000230)2.01540399
75Increased variability in muscle fiber diameter (HP:0003557)2.01313522
76Recurrent skin infections (HP:0001581)1.99854240
77Chest pain (HP:0100749)1.98448259
78Hepatosplenomegaly (HP:0001433)1.97885732
79Spondylolisthesis (HP:0003302)1.96615139
80Episodic fever (HP:0001954)1.96159951
81IgM deficiency (HP:0002850)1.95532494
82Broad metatarsal (HP:0001783)1.95202547
83Abnormality of the peritoneum (HP:0002585)1.94590610
84Autoimmune thrombocytopenia (HP:0001973)1.91687822
85Pulmonary embolism (HP:0002204)1.91463739
86Emphysema (HP:0002097)1.91302129
87Increased connective tissue (HP:0009025)1.90093817
88Obstructive sleep apnea (HP:0002870)1.89758608
89Thrombocytosis (HP:0001894)1.89483129
90Systemic lupus erythematosus (HP:0002725)1.89268771
91Myocardial infarction (HP:0001658)1.89256401
92Abnormality of skeletal muscle fiber size (HP:0012084)1.88937780
93Meningitis (HP:0001287)1.88803302
94Gastrointestinal stroma tumor (HP:0100723)1.88731795
95Keratoconjunctivitis (HP:0001096)1.88216463
96Polycythemia (HP:0001901)1.86488956
97Hypergammaglobulinemia (HP:0010702)1.86380402
98Sepsis (HP:0100806)1.86227820
99Short 4th metacarpal (HP:0010044)1.85254792
100Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.85254792
101Abnormal platelet volume (HP:0011876)1.84790443
102Papilloma (HP:0012740)1.84474734
103Verrucae (HP:0200043)1.84474734
104Restrictive lung disease (HP:0002091)1.84275599
105T lymphocytopenia (HP:0005403)1.84256405
106Broad face (HP:0000283)1.83687073
107Agammaglobulinemia (HP:0004432)1.81927490
108Increased IgE level (HP:0003212)1.81585023
109Upper motor neuron abnormality (HP:0002127)1.80808072
110Arterial thrombosis (HP:0004420)1.80801372
111Segmental peripheral demyelination/remyelination (HP:0003481)1.80249968
112Abnormality of glycolipid metabolism (HP:0010969)1.79249235
113Abnormality of liposaccharide metabolism (HP:0010968)1.79249235
114Abnormality of glycosphingolipid metabolism (HP:0004343)1.79249235
115Bladder diverticulum (HP:0000015)1.79167457
116Neurofibrillary tangles (HP:0002185)1.78757084
117Leukocytosis (HP:0001974)1.78502123
118Persistence of primary teeth (HP:0006335)1.77383185
119Recurrent bronchitis (HP:0002837)1.76348742
120Skin ulcer (HP:0200042)1.75909837
121Enlarged penis (HP:0000040)1.75392988
122Subacute progressive viral hepatitis (HP:0006572)1.75188650
123Asymmetric septal hypertrophy (HP:0001670)1.74767211
124Abnormality of the fingertips (HP:0001211)1.74042955
125Hypochromic anemia (HP:0001931)1.73795726
126Vertebral compression fractures (HP:0002953)1.73543544
127Striae distensae (HP:0001065)1.73161520
128Orchitis (HP:0100796)1.73098412
129Axonal loss (HP:0003447)1.72647828
130Asymmetry of the thorax (HP:0001555)1.72471649
131Fatigue (HP:0012378)1.71161335
132Impaired platelet aggregation (HP:0003540)1.70950695
133Abnormal platelet function (HP:0011869)1.70950695
134Rectal prolapse (HP:0002035)1.70349576
135Pustule (HP:0200039)1.69956487
136Distal upper limb amyotrophy (HP:0007149)1.69673931
137Upper limb amyotrophy (HP:0009129)1.69673931
138High pitched voice (HP:0001620)1.68089372
139Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.67377839
140Disinhibition (HP:0000734)1.67194142
141Hand muscle atrophy (HP:0009130)1.65319422
142Osteomyelitis (HP:0002754)1.64910662

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.74798043
2PKN23.59752370
3MAP4K13.31820381
4ERN13.10704644
5PRPF4B3.10569433
6EEF2K2.58319506
7MAP3K102.38206474
8EPHB12.16158323
9TTN2.15256984
10LRRK22.08065000
11STK102.06929120
12PTK62.06200677
13TGFBR21.96824678
14KDR1.80776620
15MAP3K131.80068754
16BLK1.77497579
17SMG11.72655949
18RIPK11.62727725
19PAK41.56120950
20SCYL21.54959493
21TNK21.54682193
22TYK21.54679643
23TBK11.54394776
24CDK121.54045286
25MAP3K141.48656842
26JAK31.47531151
27CSK1.45423227
28ZAP701.43400075
29MAP2K31.38934070
30BTK1.38864014
31BMX1.34075249
32TAOK21.31326064
33DMPK1.28519111
34KIT1.25965610
35CSF1R1.25305515
36TESK21.25013690
37GRK61.22587984
38KSR21.19912125
39PDGFRA1.18112836
40MARK21.16636132
41IRAK31.16254275
42RPS6KA41.14207897
43TIE11.13018735
44HCK1.12951010
45IRAK41.09786606
46CDC42BPA1.09438920
47ALK1.05996420
48JAK11.05379060
49SIK31.03547824
50MOS1.02227303
51FGFR41.01150836
52ITK1.00614301
53CAMK1D0.99960439
54SIK10.99213150
55FGFR30.95709241
56FES0.95287298
57CDK60.92941556
58TAOK30.91144953
59FLT30.90604054
60ILK0.90541488
61CLK10.89741451
62PTK20.86369668
63PDPK10.85719808
64TESK10.85616062
65JAK20.84427063
66SIK20.82560562
67PIM10.81143213
68MAP3K60.81015445
69NEK90.80643069
70MAP3K80.80530827
71EPHA30.79221232
72PIM20.78484308
73CAMK1G0.78169357
74TGFBR10.77016422
75NEK20.75651093
76LCK0.74759792
77NME20.74472001
78PRKCH0.74031523
79MAPK120.73952777
80HIPK20.73200907
81TRPM70.72637262
82PDK10.72544178
83MAPK70.72263218
84DYRK1B0.72143998
85MAP3K110.71588254
86RET0.70061709
87ARAF0.69912386
88PAK20.69349812
89MAP2K20.69208612
90TAOK10.68332863
91PDGFRB0.67653053
92MARK30.67413578
93SYK0.66927668
94FGR0.66626328
95CHUK0.62668387
96TEC0.61664883
97MATK0.59574843
98MAP3K70.59554622
99MTOR0.59538863
100TXK0.58421024
101IKBKB0.57327118
102FYN0.57274057
103YES10.56701900
104PRKD20.56341392
105IRAK20.56015578
106PRKG20.55716263
107ICK0.54742685
108IKBKE0.54295751
109MAP3K10.53551773
110RIPK40.53124490
111MAPKAPK20.52969063
112CDK40.51704777
113PRKD10.51318662
114MAP3K30.50089922
115RPS6KA60.49676858
116EGFR0.48504564
117STK380.48485028
118LYN0.47082764
119CAMKK10.46846064
120RPS6KL10.45880750
121RPS6KC10.45880750
122STK40.45098612
123RPS6KA20.44741700
124EPHB20.44578443
125CDK90.43077912
126GRK70.42452565
127DDR20.41833254
128SGK30.41708527
129PTK2B0.39121038

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.44051263
2Osteoclast differentiation_Homo sapiens_hsa043802.13365625
3B cell receptor signaling pathway_Homo sapiens_hsa046622.09371245
4Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.98881006
5Chronic myeloid leukemia_Homo sapiens_hsa052201.96676659
6Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.93255987
7Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.80444688
8* Leukocyte transendothelial migration_Homo sapiens_hsa046701.80413033
9Glycosaminoglycan degradation_Homo sapiens_hsa005311.78216740
10Allograft rejection_Homo sapiens_hsa053301.77806224
11Graft-versus-host disease_Homo sapiens_hsa053321.74792002
12AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.67958367
13Shigellosis_Homo sapiens_hsa051311.65391447
14Antigen processing and presentation_Homo sapiens_hsa046121.63910825
15Autoimmune thyroid disease_Homo sapiens_hsa053201.63029524
16Acute myeloid leukemia_Homo sapiens_hsa052211.61853631
17* Toxoplasmosis_Homo sapiens_hsa051451.58802646
18Viral myocarditis_Homo sapiens_hsa054161.56549170
19Pancreatic cancer_Homo sapiens_hsa052121.50214378
20Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.49106778
21Lysosome_Homo sapiens_hsa041421.46196544
22Toll-like receptor signaling pathway_Homo sapiens_hsa046201.44876876
23Primary immunodeficiency_Homo sapiens_hsa053401.44642788
24Focal adhesion_Homo sapiens_hsa045101.42334062
25NF-kappa B signaling pathway_Homo sapiens_hsa040641.41974543
26Small cell lung cancer_Homo sapiens_hsa052221.40897171
27Measles_Homo sapiens_hsa051621.39039492
28Other glycan degradation_Homo sapiens_hsa005111.37842380
29Tuberculosis_Homo sapiens_hsa051521.36883781
30Proteoglycans in cancer_Homo sapiens_hsa052051.35874811
31Staphylococcus aureus infection_Homo sapiens_hsa051501.34168742
32Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.33071050
33VEGF signaling pathway_Homo sapiens_hsa043701.31505672
34Malaria_Homo sapiens_hsa051441.30599733
35* Platelet activation_Homo sapiens_hsa046111.29923515
36Salmonella infection_Homo sapiens_hsa051321.29659163
37Hepatitis B_Homo sapiens_hsa051611.28513620
38Neurotrophin signaling pathway_Homo sapiens_hsa047221.28343700
39Apoptosis_Homo sapiens_hsa042101.27813471
40Notch signaling pathway_Homo sapiens_hsa043301.26562506
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.26519382
42Jak-STAT signaling pathway_Homo sapiens_hsa046301.26026724
43Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.25516731
44Adherens junction_Homo sapiens_hsa045201.24987295
45Amoebiasis_Homo sapiens_hsa051461.24790208
46* Chemokine signaling pathway_Homo sapiens_hsa040621.20930508
47* Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.20125282
48Hematopoietic cell lineage_Homo sapiens_hsa046401.20102868
49TNF signaling pathway_Homo sapiens_hsa046681.19821678
50T cell receptor signaling pathway_Homo sapiens_hsa046601.18376077
51Bladder cancer_Homo sapiens_hsa052191.17543010
52Non-small cell lung cancer_Homo sapiens_hsa052231.17531669
53Type I diabetes mellitus_Homo sapiens_hsa049401.15487316
54* Pertussis_Homo sapiens_hsa051331.14454218
55Legionellosis_Homo sapiens_hsa051341.12119931
56Regulation of actin cytoskeleton_Homo sapiens_hsa048101.12114582
57Renal cell carcinoma_Homo sapiens_hsa052111.10410292
58Colorectal cancer_Homo sapiens_hsa052101.09243771
59ECM-receptor interaction_Homo sapiens_hsa045121.07115459
60Prolactin signaling pathway_Homo sapiens_hsa049171.07064277
61MicroRNAs in cancer_Homo sapiens_hsa052061.06756574
62Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.05434289
63HTLV-I infection_Homo sapiens_hsa051661.03833358
64Rheumatoid arthritis_Homo sapiens_hsa053230.99728046
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.99305428
66Influenza A_Homo sapiens_hsa051640.99213584
67Herpes simplex infection_Homo sapiens_hsa051680.98761043
68African trypanosomiasis_Homo sapiens_hsa051430.97388437
69Viral carcinogenesis_Homo sapiens_hsa052030.94293824
70Endometrial cancer_Homo sapiens_hsa052130.93027400
71Endocytosis_Homo sapiens_hsa041440.92622254
72Transcriptional misregulation in cancer_Homo sapiens_hsa052020.91090169
73Glioma_Homo sapiens_hsa052140.89629444
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89343131
75Insulin resistance_Homo sapiens_hsa049310.89311911
76HIF-1 signaling pathway_Homo sapiens_hsa040660.88540523
77NOD-like receptor signaling pathway_Homo sapiens_hsa046210.88083677
78Prion diseases_Homo sapiens_hsa050200.87576776
79mTOR signaling pathway_Homo sapiens_hsa041500.86927709
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86493454
81Dorso-ventral axis formation_Homo sapiens_hsa043200.82027662
82Prostate cancer_Homo sapiens_hsa052150.80150410
83RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.79144041
84GnRH signaling pathway_Homo sapiens_hsa049120.78424641
85Thyroid cancer_Homo sapiens_hsa052160.77375722
86* Pathways in cancer_Homo sapiens_hsa052000.76667841
87Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75633242
88Hepatitis C_Homo sapiens_hsa051600.74215279
89Central carbon metabolism in cancer_Homo sapiens_hsa052300.72045500
90Phagosome_Homo sapiens_hsa041450.71678062
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70200248
92* Rap1 signaling pathway_Homo sapiens_hsa040150.66999685
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.66497417
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.65479751
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.64241650
96Epstein-Barr virus infection_Homo sapiens_hsa051690.64107073
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63388819
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.62847090
99Choline metabolism in cancer_Homo sapiens_hsa052310.62649635
100FoxO signaling pathway_Homo sapiens_hsa040680.61738282
101PI3K-Akt signaling pathway_Homo sapiens_hsa041510.60481717
102ErbB signaling pathway_Homo sapiens_hsa040120.60479051
103Type II diabetes mellitus_Homo sapiens_hsa049300.59170013
104p53 signaling pathway_Homo sapiens_hsa041150.59092022
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.58448666
106Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57889782
107Asthma_Homo sapiens_hsa053100.57140827
108* Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56514105
109* Sphingolipid signaling pathway_Homo sapiens_hsa040710.56291704
110Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55750934
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55408821
112Insulin signaling pathway_Homo sapiens_hsa049100.54885143
113Dilated cardiomyopathy_Homo sapiens_hsa054140.51512632
114* Estrogen signaling pathway_Homo sapiens_hsa049150.49705124
115MAPK signaling pathway_Homo sapiens_hsa040100.47230875
116Melanoma_Homo sapiens_hsa052180.46248747
117Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45260998

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