GNG10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.80796561
2viral transcription (GO:0019083)5.02978883
3translational termination (GO:0006415)4.82698736
4SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.72230123
5cotranslational protein targeting to membrane (GO:0006613)4.69715849
6protein targeting to ER (GO:0045047)4.62470370
7ribosomal small subunit biogenesis (GO:0042274)4.51400623
8protein localization to endoplasmic reticulum (GO:0070972)4.41663230
9establishment of protein localization to endoplasmic reticulum (GO:0072599)4.39157712
10translational elongation (GO:0006414)4.04569935
11detection of molecule of bacterial origin (GO:0032490)4.00613277
12DNA deamination (GO:0045006)3.99505566
13viral life cycle (GO:0019058)3.86701345
14negative regulation of interleukin-12 production (GO:0032695)3.84192812
15modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.82175940
16positive regulation by organism of defense response of other organism involved in symbiotic interact3.82175940
17modulation by symbiont of host immune response (GO:0052553)3.82175940
18positive regulation by symbiont of host defense response (GO:0052509)3.82175940
19modulation by symbiont of host defense response (GO:0052031)3.82175940
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.82175940
21cellular protein complex disassembly (GO:0043624)3.80253749
22neutrophil activation involved in immune response (GO:0002283)3.64544024
23antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.58357416
24positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.57192566
25macrophage activation involved in immune response (GO:0002281)3.52243548
26antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.50501430
27nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.48533019
28antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.46965826
29translational initiation (GO:0006413)3.40234605
30signal peptide processing (GO:0006465)3.36647199
31regulation of B cell receptor signaling pathway (GO:0050855)3.33629909
32granulocyte activation (GO:0036230)3.29194296
33regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.28546477
34mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.25813547
35ATP synthesis coupled proton transport (GO:0015986)3.25633551
36energy coupled proton transport, down electrochemical gradient (GO:0015985)3.25633551
37response to interferon-beta (GO:0035456)3.25390294
38Arp2/3 complex-mediated actin nucleation (GO:0034314)3.23424415
39platelet dense granule organization (GO:0060155)3.23291076
40cellular response to interferon-beta (GO:0035458)3.17735583
41chaperone-mediated protein transport (GO:0072321)3.16978889
42sequestering of actin monomers (GO:0042989)3.16296958
43protein targeting to membrane (GO:0006612)3.16060539
44protein complex disassembly (GO:0043241)3.15486248
45response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.15437856
46response to host immune response (GO:0052572)3.15437856
47proteasome assembly (GO:0043248)3.14711206
48maturation of SSU-rRNA (GO:0030490)3.12955395
49detection of external biotic stimulus (GO:0098581)3.11026978
50translation (GO:0006412)3.10655095
51regulation of interferon-beta biosynthetic process (GO:0045357)3.09720495
52phagosome maturation (GO:0090382)3.09515142
53telomere maintenance via semi-conservative replication (GO:0032201)3.07339232
54macrophage activation (GO:0042116)3.03744093
55leukocyte migration involved in inflammatory response (GO:0002523)3.03293788
56detection of other organism (GO:0098543)3.02750772
57positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.01300028
58macromolecular complex disassembly (GO:0032984)2.99825336
59mast cell activation (GO:0045576)2.99504173
60negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.97793237
61negative regulation of phagocytosis (GO:0050765)2.97434886
62regulation of podosome assembly (GO:0071801)2.97249012
63positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.96366426
64ribosomal large subunit biogenesis (GO:0042273)2.95584525
65protein neddylation (GO:0045116)2.94937416
66production of molecular mediator involved in inflammatory response (GO:0002532)2.91834362
67respiratory burst (GO:0045730)2.89932040
68mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.89245265
69mitochondrial respiratory chain complex I assembly (GO:0032981)2.89245265
70NADH dehydrogenase complex assembly (GO:0010257)2.89245265
71transcription elongation from RNA polymerase III promoter (GO:0006385)2.88571994
72termination of RNA polymerase III transcription (GO:0006386)2.88571994
73respiratory chain complex IV assembly (GO:0008535)2.86126603
74microglial cell activation (GO:0001774)2.85023366
75oligosaccharide catabolic process (GO:0009313)2.84444697
76DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.82530989
77purine nucleotide salvage (GO:0032261)2.82126407
78antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.82095274
79protein complex biogenesis (GO:0070271)2.81448980
80lipopolysaccharide-mediated signaling pathway (GO:0031663)2.80155449
81negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.78563554
82negative regulation of ligase activity (GO:0051352)2.78563554
83response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.77643960
84response to host (GO:0075136)2.77643960
85response to host defenses (GO:0052200)2.77643960
86signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.74610497
87intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.74610497
88establishment of protein localization to mitochondrial membrane (GO:0090151)2.74572177
89GTP biosynthetic process (GO:0006183)2.73950531
90telomere maintenance via recombination (GO:0000722)2.73033049
91cytochrome complex assembly (GO:0017004)2.71994676
92B cell mediated immunity (GO:0019724)2.71460786
93regulation of cellular amino acid metabolic process (GO:0006521)2.70131768
94detection of biotic stimulus (GO:0009595)2.70019545
95negative regulation of hydrogen peroxide-induced cell death (GO:1903206)2.69395060
96signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.69338923
97signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.69338923
98signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.69338923
99regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.67373142
100deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.67131320
101myeloid cell activation involved in immune response (GO:0002275)2.66390022
102respiratory electron transport chain (GO:0022904)2.65451342
103regulation of B cell differentiation (GO:0045577)2.65096998
104regulation of protein heterodimerization activity (GO:0043497)2.62609932
105positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.60354207
106regulation of interferon-alpha production (GO:0032647)2.60058124
107anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.59873026
108leukocyte aggregation (GO:0070486)2.59696585
109defense response to protozoan (GO:0042832)2.59031298
110negative regulation of interleukin-17 production (GO:0032700)2.58144831
111electron transport chain (GO:0022900)2.57489461
112response to peptidoglycan (GO:0032494)2.57284654
113positive regulation of mast cell degranulation (GO:0043306)2.57151849
114positive regulation of mast cell activation involved in immune response (GO:0033008)2.57151849
115nuclear-transcribed mRNA catabolic process (GO:0000956)2.56783997
116lymphoid progenitor cell differentiation (GO:0002320)2.56151893
117detection of bacterium (GO:0016045)2.55716764
118cellular response to zinc ion (GO:0071294)2.55384316
119positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.53228663
120positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.52544881
121positive regulation of B cell differentiation (GO:0045579)2.52115212
122chronic inflammatory response (GO:0002544)2.51871719
123signal transduction involved in DNA integrity checkpoint (GO:0072401)2.51521292
124signal transduction involved in DNA damage checkpoint (GO:0072422)2.51521292
125mitochondrial respiratory chain complex assembly (GO:0033108)2.51273051
126protein maturation by protein folding (GO:0022417)2.50122590
127signal transduction involved in cell cycle checkpoint (GO:0072395)2.49854943
128DNA strand elongation involved in DNA replication (GO:0006271)2.49819830
129phagocytosis, engulfment (GO:0006911)2.49741944
130positive regulation of monocyte chemotaxis (GO:0090026)2.48066775
131positive regulation of interferon-alpha production (GO:0032727)2.47561651
132positive regulation of mast cell activation (GO:0033005)2.47519021
133positive regulation of interleukin-6 production (GO:0032755)2.47362925
134T-helper 1 type immune response (GO:0042088)2.46897832
135regulation of mononuclear cell migration (GO:0071675)2.46876321
136histamine secretion (GO:0001821)2.46353656
137positive regulation of toll-like receptor signaling pathway (GO:0034123)2.46334356
138regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.46163991
139negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.45847668
140negative regulation of cell killing (GO:0031342)2.45847668
141myeloid dendritic cell activation (GO:0001773)2.45747477
142cellular extravasation (GO:0045123)2.45561535
143positive regulation of ligase activity (GO:0051351)2.45282810
144positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.45224417
145DNA strand elongation (GO:0022616)2.44827569
146mRNA catabolic process (GO:0006402)2.44565905
147immunoglobulin mediated immune response (GO:0016064)2.43837858
148mannosylation (GO:0097502)2.42854556
149interferon-gamma-mediated signaling pathway (GO:0060333)2.42532005
150nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.42196089
151regulation of oxidative phosphorylation (GO:0002082)2.41011019
152regulation of mast cell degranulation (GO:0043304)2.40471009
153negative regulation of response to reactive oxygen species (GO:1901032)2.40286881
154nucleotide-excision repair, DNA gap filling (GO:0006297)2.40164679
155establishment of integrated proviral latency (GO:0075713)2.40078499
156nucleoside salvage (GO:0043174)2.39654481
157regulation of cytokine secretion involved in immune response (GO:0002739)2.39413232
158mitotic recombination (GO:0006312)2.39100817
159positive regulation of actin filament depolymerization (GO:0030836)2.38867131
160exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.38815034
161establishment of viral latency (GO:0019043)2.37288636
162response to protozoan (GO:0001562)2.37235042
163purine-containing compound salvage (GO:0043101)2.37185131
164mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.36977024
165positive regulation of leukocyte degranulation (GO:0043302)2.36745711
166neutrophil activation (GO:0042119)2.34064082
167actin nucleation (GO:0045010)2.33441507
168B cell receptor signaling pathway (GO:0050853)2.32462145
169guanosine-containing compound biosynthetic process (GO:1901070)2.32367448
170CTP metabolic process (GO:0046036)2.32018833
171CTP biosynthetic process (GO:0006241)2.32018833

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.24641442
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.71541584
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.69511385
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.25675775
5ELF1_17652178_ChIP-ChIP_JURKAT_Human3.17047410
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.16048628
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.12580044
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.11128821
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.06128403
10BP1_19119308_ChIP-ChIP_Hs578T_Human3.02615346
11* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.95700540
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.87903506
13SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.87541112
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.76844286
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.65232952
16* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.63557701
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.60409031
18E2F7_22180533_ChIP-Seq_HELA_Human2.57020971
19FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.50745931
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.50008327
21ELK1_19687146_ChIP-ChIP_HELA_Human2.47402086
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.43858274
23TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.32769110
24ETS1_20019798_ChIP-Seq_JURKAT_Human2.31471584
25VDR_23849224_ChIP-Seq_CD4+_Human2.29612808
26SPI1_23547873_ChIP-Seq_NB4_Human2.26122069
27TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.25079617
28CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.22097611
29HOXB4_20404135_ChIP-ChIP_EML_Mouse2.16907866
30CREB1_15753290_ChIP-ChIP_HEK293T_Human2.12430100
31CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.08446730
32SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.07583298
33Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.07364446
34STAT4_19710469_ChIP-ChIP_TH1__Mouse2.06800580
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.03305222
36MYC_18358816_ChIP-ChIP_MESCs_Mouse2.01972619
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.98190548
38* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.92591858
39CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.85045271
40HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.84740178
41SCL_19346495_ChIP-Seq_HPC-7_Human1.82650599
42SRF_21415370_ChIP-Seq_HL-1_Mouse1.82321047
43* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.82059408
44IRF8_27001747_Chip-Seq_BMDM_Mouse1.80075934
45* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.79386339
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.76647392
47FOXP3_21729870_ChIP-Seq_TREG_Human1.74914753
48* DCP1A_22483619_ChIP-Seq_HELA_Human1.71165419
49XRN2_22483619_ChIP-Seq_HELA_Human1.66719784
50LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.60481949
51RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.60009078
52TTF2_22483619_ChIP-Seq_HELA_Human1.59449330
53MYC_19030024_ChIP-ChIP_MESCs_Mouse1.58801495
54GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.56894469
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.56741997
56MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.53011872
57SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.50421002
58HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.47690856
59ELK1_22589737_ChIP-Seq_MCF10A_Human1.45820463
60MYC_19079543_ChIP-ChIP_MESCs_Mouse1.44068833
61E2F1_18555785_ChIP-Seq_MESCs_Mouse1.43560454
62PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.41951903
63ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41651820
64* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.40390625
65E2F4_17652178_ChIP-ChIP_JURKAT_Human1.39754191
66E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.38893085
67SMAD_19615063_ChIP-ChIP_OVARY_Human1.38325676
68PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38222377
69ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.37765844
70VDR_24763502_ChIP-Seq_THP-1_Human1.37205851
71MYB_26560356_Chip-Seq_TH2_Human1.36609637
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.35571215
73CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.34732677
74STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.33887698
75GABP_19822575_ChIP-Seq_HepG2_Human1.33631788
76STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.28605812
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.28098968
78ELF5_23300383_ChIP-Seq_T47D_Human1.25294046
79NELFA_20434984_ChIP-Seq_ESCs_Mouse1.24265060
80PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22816979
81* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.20866186
82RBPJ_22232070_ChIP-Seq_NCS_Mouse1.19607622
83CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.19401372
84STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.18824115
85EGR1_19374776_ChIP-ChIP_THP-1_Human1.18610171
86IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.14619701
87TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14388572
88YY1_21170310_ChIP-Seq_MESCs_Mouse1.13734286
89* RUNX1_22412390_ChIP-Seq_EML_Mouse1.13484812
90ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13203303
91LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.11822774
92AR_21909140_ChIP-Seq_LNCAP_Human1.10115057
93STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.10024141
94PADI4_21655091_ChIP-ChIP_MCF-7_Human1.08919872
95SALL4_18804426_ChIP-ChIP_XEN_Mouse1.06408118
96MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05487990
97PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05185791
98IKZF1_21737484_ChIP-ChIP_HCT116_Human1.04693240
99NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.04007177
100FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.03988997
101SOX2_20726797_ChIP-Seq_SW620_Human1.03813947
102VDR_21846776_ChIP-Seq_THP-1_Human1.01989232
103FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.00618298
104* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.99434178
105VDR_24787735_ChIP-Seq_THP-1_Human0.97549642
106PU_27001747_Chip-Seq_BMDM_Mouse0.97364648
107MYC_18940864_ChIP-ChIP_HL60_Human0.97028930
108NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95870153
109CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.94432719
110ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93287681
111SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.92682264
112SOX17_20123909_ChIP-Seq_XEN_Mouse0.92665794
113SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92237921
114PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.91737680
115GATA1_22025678_ChIP-Seq_K562_Human0.91668821
116CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.91317573
117BRD4_25478319_ChIP-Seq_HGPS_Human0.90296885
118GATA3_26560356_Chip-Seq_TH2_Human0.90111018
119CIITA_25753668_ChIP-Seq_RAJI_Human0.89978506
120CTCF_18555785_ChIP-Seq_MESCs_Mouse0.89857277
121EWS_26573619_Chip-Seq_HEK293_Human0.88778879
122SPI1_23127762_ChIP-Seq_K562_Human0.88719065
123MYB_26560356_Chip-Seq_TH1_Human0.88718141
124PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.87996852
125TFEB_21752829_ChIP-Seq_HELA_Human0.87543895
126CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87524728
127ZFX_18555785_ChIP-Seq_MESCs_Mouse0.87116997
128CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.85976377
129PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.85915854
130IGF1R_20145208_ChIP-Seq_DFB_Human0.84692281
131MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.84456212
132CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81488710
133MAF_26560356_Chip-Seq_TH1_Human0.81390168
134TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.81272768
135GATA2_22383799_ChIP-Seq_G1ME_Mouse0.81158849
136CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.78548114
137HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.77451738
138FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.76639669
139GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.76572942

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.30519336
2MP0003806_abnormal_nucleotide_metabolis4.15185749
3MP0002148_abnormal_hypersensitivity_rea3.11737184
4MP0009379_abnormal_foot_pigmentation3.03748457
5MP0009785_altered_susceptibility_to2.98867907
6MP0005671_abnormal_response_to2.84180667
7MP0003191_abnormal_cellular_cholesterol2.81311168
8MP0005000_abnormal_immune_tolerance2.66825572
9MP0005025_abnormal_response_to2.42984805
10MP0003724_increased_susceptibility_to2.39948196
11MP0002419_abnormal_innate_immunity2.38787726
12MP0002396_abnormal_hematopoietic_system2.35349803
13MP0002452_abnormal_antigen_presenting2.34814921
14MP0002420_abnormal_adaptive_immunity2.27096053
15MP0001819_abnormal_immune_cell2.25627004
16MP0003436_decreased_susceptibility_to2.25613904
17MP0000685_abnormal_immune_system2.24937021
18MP0001800_abnormal_humoral_immune2.23064582
19MP0002723_abnormal_immune_serum2.19848075
20MP0009333_abnormal_splenocyte_physiolog2.18143385
21MP0001853_heart_inflammation2.18122469
22MP0008438_abnormal_cutaneous_collagen2.04448906
23MP0000015_abnormal_ear_pigmentation2.02986379
24MP0005451_abnormal_body_composition2.01707810
25MP0002277_abnormal_respiratory_mucosa2.00790739
26MP0001790_abnormal_immune_system2.00199419
27MP0005387_immune_system_phenotype2.00199419
28MP0008004_abnormal_stomach_pH1.94011680
29MP0003195_calcinosis1.91477819
30MP0005174_abnormal_tail_pigmentation1.90581588
31MP0002398_abnormal_bone_marrow1.89517068
32MP0006082_CNS_inflammation1.88582823
33MP0003763_abnormal_thymus_physiology1.80871137
34MP0005503_abnormal_tendon_morphology1.78547458
35MP0000716_abnormal_immune_system1.76788618
36MP0002139_abnormal_hepatobiliary_system1.72722897
37MP0008260_abnormal_autophagy1.69658971
38MP0002095_abnormal_skin_pigmentation1.66984478
39MP0006054_spinal_hemorrhage1.63750724
40MP0002405_respiratory_system_inflammati1.62791964
41MP0003300_gastrointestinal_ulcer1.61725708
42MP0002933_joint_inflammation1.60948047
43MP0001905_abnormal_dopamine_level1.59219933
44MP0000372_irregular_coat_pigmentation1.56710696
45MP0003303_peritoneal_inflammation1.56212027
46MP0000858_altered_metastatic_potential1.51908739
47MP0000689_abnormal_spleen_morphology1.50431147
48MP0001533_abnormal_skeleton_physiology1.50314785
49MP0004808_abnormal_hematopoietic_stem1.49977876
50MP0005166_decreased_susceptibility_to1.49782563
51MP0002429_abnormal_blood_cell1.49683611
52MP0005464_abnormal_platelet_physiology1.48029048
53MP0002006_tumorigenesis1.45631386
54MP0002877_abnormal_melanocyte_morpholog1.45009938
55MP0002722_abnormal_immune_system1.41064854
56MP0002166_altered_tumor_susceptibility1.40575555
57MP0002254_reproductive_system_inflammat1.40313618
58MP0003828_pulmonary_edema1.39568730
59MP0003880_abnormal_central_pattern1.39342278
60MP0006036_abnormal_mitochondrial_physio1.36300953
61MP0001188_hyperpigmentation1.34715981
62MP0000343_altered_response_to1.33944628
63MP0001845_abnormal_inflammatory_respons1.33315209
64MP0003279_aneurysm1.32118856
65MP0000465_gastrointestinal_hemorrhage1.27292037
66MP0005397_hematopoietic_system_phenotyp1.24826455
67MP0001545_abnormal_hematopoietic_system1.24826455
68MP0003950_abnormal_plasma_membrane1.23578352
69MP0005075_abnormal_melanosome_morpholog1.23578294
70MP0009840_abnormal_foam_cell1.21429720
71MP0000490_abnormal_crypts_of1.21286375
72MP0001529_abnormal_vocalization1.20503221
73MP0001986_abnormal_taste_sensitivity1.20479074
74MP0001542_abnormal_bone_strength1.19577171
75MP0008007_abnormal_cellular_replicative1.19542988
76MP0002163_abnormal_gland_morphology1.18093001
77MP0000681_abnormal_thyroid_gland1.17831808
78MP0002837_dystrophic_cardiac_calcinosis1.17445437
79MP0005165_increased_susceptibility_to1.15686872
80MP0005408_hypopigmentation1.14708955
81MP0000703_abnormal_thymus_morphology1.13854119
82MP0010155_abnormal_intestine_physiology1.12914801
83MP0003172_abnormal_lysosome_physiology1.11417723
84MP0002938_white_spotting1.10937713
85MP0001958_emphysema1.08594849
86MP0005409_darkened_coat_color1.06316982
87MP0009697_abnormal_copulation1.05917018
88MP0001764_abnormal_homeostasis1.05249660
89MP0010234_abnormal_vibrissa_follicle1.04981735
90MP0002090_abnormal_vision1.01380984
91MP0002638_abnormal_pupillary_reflex1.01009280
92MP0005390_skeleton_phenotype0.98867995
93MP0005164_abnormal_response_to0.97834527
94MP0004510_myositis0.97302501
95MP0008058_abnormal_DNA_repair0.96281020
96MP0008469_abnormal_protein_level0.96105410
97MP0009763_increased_sensitivity_to0.94684662
98MP0003448_altered_tumor_morphology0.94436680
99MP0003866_abnormal_defecation0.93214674
100MP0010352_gastrointestinal_tract_polyps0.93056997
101MP0005319_abnormal_enzyme/_coenzyme0.92736288
102MP0000604_amyloidosis0.91268724
103MP0005084_abnormal_gallbladder_morpholo0.89783114
104MP0005085_abnormal_gallbladder_physiolo0.89417664
105MP0004947_skin_inflammation0.89046443
106MP0002332_abnormal_exercise_endurance0.86463001
107MP0000569_abnormal_digit_pigmentation0.84800304
108MP0010094_abnormal_chromosome_stability0.84004147
109MP0002132_abnormal_respiratory_system0.83496192
110MP0003186_abnormal_redox_activity0.83024301
111MP0005376_homeostasis/metabolism_phenot0.82874325
112MP0002998_abnormal_bone_remodeling0.81923776
113MP0000920_abnormal_myelination0.80483509
114MP0002295_abnormal_pulmonary_circulatio0.80458026
115MP0002736_abnormal_nociception_after0.79893230
116MP0005023_abnormal_wound_healing0.79680420
117MP0004134_abnormal_chest_morphology0.79116408
118MP0004883_abnormal_blood_vessel0.78657308
119MP0006276_abnormal_autonomic_nervous0.78063124
120MP0003011_delayed_dark_adaptation0.76040923
121MP0005310_abnormal_salivary_gland0.75440914
122MP0005379_endocrine/exocrine_gland_phen0.72600368
123MP0002019_abnormal_tumor_incidence0.71673345
124MP0003795_abnormal_bone_structure0.71215119
125MP0005365_abnormal_bile_salt0.70921561
126MP0003075_altered_response_to0.70497417
127MP0006035_abnormal_mitochondrial_morpho0.70096797
128MP0001243_abnormal_dermal_layer0.69331859
129MP0001968_abnormal_touch/_nociception0.69299724
130MP0002693_abnormal_pancreas_physiology0.68894659
131MP0001873_stomach_inflammation0.68650736
132MP0003077_abnormal_cell_cycle0.66261005
133MP0009764_decreased_sensitivity_to0.64622751
134MP0004957_abnormal_blastocyst_morpholog0.63071154
135MP0002735_abnormal_chemical_nociception0.61768614
136MP0010386_abnormal_urinary_bladder0.60894338
137MP0005058_abnormal_lysosome_morphology0.59788093
138MP0004142_abnormal_muscle_tone0.59663379
139MP0005171_absent_coat_pigmentation0.57712797
140MP0008873_increased_physiological_sensi0.57338179

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.45251350
2Recurrent abscess formation (HP:0002722)4.32970850
3Elevated erythrocyte sedimentation rate (HP:0003565)4.32324064
4Abnormality of glycolipid metabolism (HP:0010969)4.29741107
5Abnormality of liposaccharide metabolism (HP:0010968)4.29741107
6Abnormality of glycosphingolipid metabolism (HP:0004343)4.29741107
7Abnormal number of erythroid precursors (HP:0012131)4.26179331
8Recurrent bacterial skin infections (HP:0005406)3.79711796
9Increased hepatocellular lipid droplets (HP:0006565)3.52787978
10Mitochondrial inheritance (HP:0001427)3.43032078
11Exertional dyspnea (HP:0002875)3.40391516
12Reticulocytopenia (HP:0001896)3.36228271
13Myositis (HP:0100614)3.36048860
14Thrombocytosis (HP:0001894)3.33669839
15Acute necrotizing encephalopathy (HP:0006965)3.32898562
16Type I transferrin isoform profile (HP:0003642)3.27243757
17Recurrent gram-negative bacterial infections (HP:0005420)3.22406117
18Loss of speech (HP:0002371)3.20917419
19Aplastic anemia (HP:0001915)3.08243999
20IgM deficiency (HP:0002850)3.04927809
21Disinhibition (HP:0000734)3.04377451
22Hepatosplenomegaly (HP:0001433)2.99231514
23Abnormal mitochondria in muscle tissue (HP:0008316)2.96486679
24Renal Fanconi syndrome (HP:0001994)2.94950251
253-Methylglutaconic aciduria (HP:0003535)2.92549249
26Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.92296730
27Hepatocellular necrosis (HP:0001404)2.91568300
28Pallor (HP:0000980)2.91462007
29Progressive neurologic deterioration (HP:0002344)2.85816783
30Chronic obstructive pulmonary disease (HP:0006510)2.81969462
31Obstructive lung disease (HP:0006536)2.81969462
32Lipid accumulation in hepatocytes (HP:0006561)2.79519635
33Petechiae (HP:0000967)2.77033103
34Eczematoid dermatitis (HP:0000976)2.76528081
35Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.76326626
36Progressive macrocephaly (HP:0004481)2.73880211
37Increased CSF lactate (HP:0002490)2.70530766
38Mediastinal lymphadenopathy (HP:0100721)2.67973870
39Chronic otitis media (HP:0000389)2.66345190
40Abnormal protein glycosylation (HP:0012346)2.65545633
41Abnormal glycosylation (HP:0012345)2.65545633
42Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.65545633
43Abnormal protein N-linked glycosylation (HP:0012347)2.65545633
44Systemic lupus erythematosus (HP:0002725)2.62797321
45Poor head control (HP:0002421)2.62102315
46Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.61408030
47Decreased activity of mitochondrial respiratory chain (HP:0008972)2.61408030
48Recurrent skin infections (HP:0001581)2.60794262
49Meningitis (HP:0001287)2.59959063
50Macrocytic anemia (HP:0001972)2.57569338
51Axonal loss (HP:0003447)2.55391857
52Nausea (HP:0002018)2.53185121
53Abnormality of aromatic amino acid family metabolism (HP:0004338)2.53088254
54Reduced antithrombin III activity (HP:0001976)2.50477954
55Vertebral compression fractures (HP:0002953)2.49845997
56Keratoconjunctivitis sicca (HP:0001097)2.45408512
57Anorexia (HP:0002039)2.45348142
58Abnormality of methionine metabolism (HP:0010901)2.42378872
59Panhypogammaglobulinemia (HP:0003139)2.41674301
60Tetraparesis (HP:0002273)2.41627771
61Recurrent bronchitis (HP:0002837)2.41183982
62Cerebral edema (HP:0002181)2.39754112
63Increased cerebral lipofuscin (HP:0011813)2.39333059
64Recurrent pneumonia (HP:0006532)2.37872051
65Hypothermia (HP:0002045)2.36490065
66Vacuolated lymphocytes (HP:0001922)2.35480804
67Agammaglobulinemia (HP:0004432)2.33468887
68Mutism (HP:0002300)2.33246856
69Increased intramyocellular lipid droplets (HP:0012240)2.32416341
70Keratoconjunctivitis (HP:0001096)2.31786172
71Recurrent lower respiratory tract infections (HP:0002783)2.29235283
72Cellulitis (HP:0100658)2.23557799
73Retrobulbar optic neuritis (HP:0100654)2.22806121
74Optic neuritis (HP:0100653)2.22806121
75Patchy hypopigmentation of hair (HP:0011365)2.22527989
76Respiratory failure (HP:0002878)2.21089027
77Hepatic necrosis (HP:0002605)2.21048874
78Vasculitis (HP:0002633)2.20975291
79Palpitations (HP:0001962)2.20935819
80Conjunctival hamartoma (HP:0100780)2.18960404
81Urticaria (HP:0001025)2.18321602
82Respiratory difficulties (HP:0002880)2.18148486
83Bone cyst (HP:0012062)2.17880943
84IgG deficiency (HP:0004315)2.16190780
85Nuclear cataract (HP:0100018)2.14673406
86Myocardial infarction (HP:0001658)2.12527768
87Acute encephalopathy (HP:0006846)2.11954095
88Recurrent viral infections (HP:0004429)2.11895296
89Generalized aminoaciduria (HP:0002909)2.10750142
90Congenital, generalized hypertrichosis (HP:0004540)2.10601779
91Dysostosis multiplex (HP:0000943)2.10218961
92Orchitis (HP:0100796)2.08877992
93Syringomyelia (HP:0003396)2.08176076
94Spinal cord lesions (HP:0100561)2.08176076
95Abnormality of T cell physiology (HP:0011840)2.07814551
96Abnormality of macrophages (HP:0004311)2.07096256
97Basal ganglia calcification (HP:0002135)2.05544089
98Recurrent fungal infections (HP:0002841)2.05493418
99Parakeratosis (HP:0001036)2.05214102
100Amyloidosis (HP:0011034)2.05131802
101Stomatitis (HP:0010280)2.04763917
102Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.03965909
103Chronic mucocutaneous candidiasis (HP:0002728)2.01892804
104Recurrent cutaneous fungal infections (HP:0011370)2.01892804
105Hematochezia (HP:0002573)1.99663374
106Heterochromia iridis (HP:0001100)1.99406706
107Papilledema (HP:0001085)1.98275842
108Increased CSF protein (HP:0002922)1.97727288
109Encephalitis (HP:0002383)1.96505114
110Abnormality of B cell number (HP:0010975)1.95443917
111B lymphocytopenia (HP:0010976)1.95443917
112Exercise intolerance (HP:0003546)1.94430355
113Episodic fever (HP:0001954)1.94310790
114Chronic sinusitis (HP:0011109)1.92705768
115Abnormality of the prostate (HP:0008775)1.92151715
116Mucosal telangiectasiae (HP:0100579)1.91383227
117Increased neuronal autofluorescent lipopigment (HP:0002074)1.90806839
118Gastrointestinal stroma tumor (HP:0100723)1.90367973
119Pulmonary fibrosis (HP:0002206)1.90073723
120Pulmonary infiltrates (HP:0002113)1.89210198
121Muscle fibrillation (HP:0010546)1.87757765
122Hypergammaglobulinemia (HP:0010702)1.86549555
123Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.85861879
124Gastrointestinal infarctions (HP:0005244)1.83869147
125White forelock (HP:0002211)1.82605248
126Beaking of vertebral bodies (HP:0004568)1.82583453
127Abnormal delayed hypersensitivity skin test (HP:0002963)1.82224064
128Abnormality of aspartate family amino acid metabolism (HP:0010899)1.81711159
129Lymphopenia (HP:0001888)1.81158723
130Retinal dysplasia (HP:0007973)1.80010355
131Osteolytic defects of the hand bones (HP:0009699)1.79816153
132Osteolytic defects of the phalanges of the hand (HP:0009771)1.79816153
133Increased IgM level (HP:0003496)1.77729529
134Abnormality of the basal ganglia (HP:0002134)1.77555113
135Gangrene (HP:0100758)1.76588084
136Lactic acidosis (HP:0003128)1.75717953
137Increased serum lactate (HP:0002151)1.75079349
138Abnormality of renal resorption (HP:0011038)1.74998923
139Agnosia (HP:0010524)1.73655915
140Peritonitis (HP:0002586)1.73323806
141Purpura (HP:0000979)1.72442050
142Abnormality of polysaccharide metabolism (HP:0011012)1.71871579
143Abnormality of glycosaminoglycan metabolism (HP:0004371)1.71871579
144Abnormality of mucopolysaccharide metabolism (HP:0011020)1.71871579
145Polyneuropathy (HP:0001271)1.71779627
146Optic disc pallor (HP:0000543)1.71272619
147Vascular calcification (HP:0004934)1.70352147
148Abnormality of cells of the lymphoid lineage (HP:0012140)1.70139526
149Thyroiditis (HP:0100646)1.70071913
150Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.69600576
151Joint stiffness (HP:0001387)1.68892294
152Leukocytosis (HP:0001974)1.68573277
153Hemoptysis (HP:0002105)1.68562696
154Abnormality of the anterior horn cell (HP:0006802)1.68365215
155Degeneration of anterior horn cells (HP:0002398)1.68365215
156Severe combined immunodeficiency (HP:0004430)1.68156913

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME23.99177871
2STK163.29496105
3PIM22.93056458
4MAP3K122.90458853
5BLK2.44421147
6VRK12.36475143
7IRAK42.22389345
8VRK22.22317124
9RIPK42.21649326
10KIT2.17004183
11TEC2.06746325
12CDK192.04407486
13MAP4K12.02636829
14PAK41.99381740
15LIMK11.96465442
16MAP3K31.87307637
17EIF2AK31.87082248
18EIF2AK11.86666648
19TNIK1.86023869
20TXK1.79696988
21TRIM281.79508228
22TESK11.66727413
23CSF1R1.65420670
24FES1.63730593
25ARAF1.63480367
26TESK21.58828331
27SYK1.49563277
28ERBB31.43279708
29BTK1.42289278
30STK101.41372531
31BMPR21.32878843
32PBK1.30082946
33BUB11.28167212
34MKNK11.26802159
35LYN1.21443954
36TBK11.18527596
37GRK71.17119737
38DYRK21.17114965
39JAK31.16538931
40ZAP701.12965746
41IKBKB1.11880864
42TAOK11.11662295
43IRAK21.09928263
44MAPK131.09861540
45CASK1.07516870
46RPS6KA41.05641293
47MYLK1.04955392
48NEK11.04470474
49MAP3K141.02253563
50TGFBR11.02224480
51TLK11.01376375
52ADRBK21.00082669
53TYK20.99277412
54TGFBR20.99252097
55EIF2AK20.95260257
56SIK30.94084905
57PRKG20.94082733
58BMPR1B0.93996994
59CLK10.93671519
60PLK30.92856320
61CDK80.91877523
62NME10.89033454
63LCK0.87063162
64NUAK10.86810466
65GRK10.84826733
66DAPK10.84646702
67IKBKE0.84571864
68MUSK0.84507477
69MAP3K50.83745074
70CAMKK20.83700132
71STK40.82998547
72MAPKAPK50.80249524
73KDR0.80153738
74PIK3CG0.77291329
75CSNK1G30.77069699
76MAP2K60.76959764
77YES10.75963611
78ABL20.75575147
79IRAK10.73608327
80MAP3K20.72933230
81MAP2K70.72921472
82ILK0.72444937
83MST40.70399386
84PLK20.70182341
85WEE10.68834111
86LRRK20.68182717
87CCNB10.66427554
88MOS0.66364325
89STK240.65689979
90JAK20.65192623
91TRPM70.63551978
92IRAK30.63437951
93PDK20.62731131
94MAP4K20.62576262
95ERBB40.62055959
96MAP3K10.61911655
97DYRK30.61702674
98ACVR1B0.61384684
99MARK10.61380257
100FGR0.59427564
101TAF10.58716286
102MATK0.58640791
103JAK10.58478330
104HCK0.57674438
105MAP3K110.57232595
106DDR20.56472779
107SCYL20.54926677
108ITK0.54625754
109FLT30.54194740
110MAPK40.54043072
111BRSK20.53681905
112RAF10.53386589
113ROCK20.52861414
114CSK0.52255672
115RPS6KA50.48766956
116TAOK20.48367729
117PRKCD0.48040828
118MAP3K130.47246257
119TNK20.47135021
120BCKDK0.46818946
121MKNK20.46164189
122ADRBK10.44935803
123SRPK10.43575277
124STK30.43428056
125PIM10.43350325
126OXSR10.41382521
127MAP2K30.40134471
128MAP3K80.40112291
129PASK0.39735719
130CDK60.39488062
131MINK10.38496773
132PTK2B0.38221138
133CSNK2A10.37461798
134DAPK30.37205454
135CDK140.36930682
136EPHB10.36452838
137ABL10.35319479
138NEK90.35273444
139LMTK20.34898242
140FER0.34777653

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.31690614
2Proteasome_Homo sapiens_hsa030503.40697874
3Protein export_Homo sapiens_hsa030602.73418729
4DNA replication_Homo sapiens_hsa030302.64227832
5Oxidative phosphorylation_Homo sapiens_hsa001902.34556012
6RNA polymerase_Homo sapiens_hsa030202.28955310
7Staphylococcus aureus infection_Homo sapiens_hsa051502.28092349
8Parkinsons disease_Homo sapiens_hsa050122.14037848
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.13456571
10Sulfur metabolism_Homo sapiens_hsa009202.07984696
11Mismatch repair_Homo sapiens_hsa034302.03930618
12Folate biosynthesis_Homo sapiens_hsa007902.00631671
13Base excision repair_Homo sapiens_hsa034101.77431186
14Primary immunodeficiency_Homo sapiens_hsa053401.74172100
15Nucleotide excision repair_Homo sapiens_hsa034201.73396904
16Alzheimers disease_Homo sapiens_hsa050101.64128875
17Pyrimidine metabolism_Homo sapiens_hsa002401.62909078
18Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.60865008
19Spliceosome_Homo sapiens_hsa030401.60765230
20Homologous recombination_Homo sapiens_hsa034401.58124210
21Allograft rejection_Homo sapiens_hsa053301.53718418
22Huntingtons disease_Homo sapiens_hsa050161.52360331
23Leishmaniasis_Homo sapiens_hsa051401.51357112
24Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.48370771
25Glutathione metabolism_Homo sapiens_hsa004801.45472827
26Graft-versus-host disease_Homo sapiens_hsa053321.45201193
27Shigellosis_Homo sapiens_hsa051311.43759942
28Pertussis_Homo sapiens_hsa051331.36281476
29Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.33990605
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.30907916
31SNARE interactions in vesicular transport_Homo sapiens_hsa041301.29786316
32Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.25958954
33Non-homologous end-joining_Homo sapiens_hsa034501.24089127
34Fatty acid elongation_Homo sapiens_hsa000621.24063570
35Intestinal immune network for IgA production_Homo sapiens_hsa046721.21636660
36Legionellosis_Homo sapiens_hsa051341.20411397
37Antigen processing and presentation_Homo sapiens_hsa046121.19816054
38Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.17598565
39Rheumatoid arthritis_Homo sapiens_hsa053231.16988677
40Asthma_Homo sapiens_hsa053101.15838626
41Other glycan degradation_Homo sapiens_hsa005111.15788229
42Malaria_Homo sapiens_hsa051441.15589897
43Hematopoietic cell lineage_Homo sapiens_hsa046401.10760843
44B cell receptor signaling pathway_Homo sapiens_hsa046621.09652284
45N-Glycan biosynthesis_Homo sapiens_hsa005101.08671011
46Measles_Homo sapiens_hsa051621.08414308
47Phagosome_Homo sapiens_hsa041451.05865867
48Salmonella infection_Homo sapiens_hsa051321.03011354
49Basal transcription factors_Homo sapiens_hsa030221.01346523
50Osteoclast differentiation_Homo sapiens_hsa043800.99360669
51Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.97499469
52NF-kappa B signaling pathway_Homo sapiens_hsa040640.96698101
53Tuberculosis_Homo sapiens_hsa051520.96474102
54Autoimmune thyroid disease_Homo sapiens_hsa053200.93406171
55Galactose metabolism_Homo sapiens_hsa000520.92969387
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.92965261
57Primary bile acid biosynthesis_Homo sapiens_hsa001200.92921652
58Epstein-Barr virus infection_Homo sapiens_hsa051690.92909610
59Viral myocarditis_Homo sapiens_hsa054160.92357752
60Toll-like receptor signaling pathway_Homo sapiens_hsa046200.90569693
61Purine metabolism_Homo sapiens_hsa002300.88828695
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.88602765
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.87823342
64Herpes simplex infection_Homo sapiens_hsa051680.86050715
65Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.84301038
66Type I diabetes mellitus_Homo sapiens_hsa049400.83414155
67RNA degradation_Homo sapiens_hsa030180.80649536
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79368350
69Vibrio cholerae infection_Homo sapiens_hsa051100.78368231
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74622981
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.74325824
72Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72358651
73Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.72037823
74Hepatitis B_Homo sapiens_hsa051610.69687040
75Apoptosis_Homo sapiens_hsa042100.69420484
76Complement and coagulation cascades_Homo sapiens_hsa046100.69359916
77Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68855485
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.68137419
79Regulation of autophagy_Homo sapiens_hsa041400.67539481
80T cell receptor signaling pathway_Homo sapiens_hsa046600.66722927
81Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.66181479
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65398697
83Mineral absorption_Homo sapiens_hsa049780.63044347
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62802335
85Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62640927
86* Chemokine signaling pathway_Homo sapiens_hsa040620.60767067
87Jak-STAT signaling pathway_Homo sapiens_hsa046300.59741218
88Pentose phosphate pathway_Homo sapiens_hsa000300.58955475
89Systemic lupus erythematosus_Homo sapiens_hsa053220.57278890
90Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.57277569
91Lysosome_Homo sapiens_hsa041420.56764819
92Cell cycle_Homo sapiens_hsa041100.55704470
93RNA transport_Homo sapiens_hsa030130.55541551
94Peroxisome_Homo sapiens_hsa041460.55455485
95Influenza A_Homo sapiens_hsa051640.52944053
96p53 signaling pathway_Homo sapiens_hsa041150.52521753
97Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.51856668
98Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50683799
99Sphingolipid metabolism_Homo sapiens_hsa006000.50520924
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.50499640
101Toxoplasmosis_Homo sapiens_hsa051450.49899539
102TNF signaling pathway_Homo sapiens_hsa046680.48086253
103Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.46832266
104Platelet activation_Homo sapiens_hsa046110.46000874
105African trypanosomiasis_Homo sapiens_hsa051430.45992853
106Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45522734
107Viral carcinogenesis_Homo sapiens_hsa052030.44497745
108Arachidonic acid metabolism_Homo sapiens_hsa005900.43766746
109Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43583239
110* Alcoholism_Homo sapiens_hsa050340.42573832
111Fanconi anemia pathway_Homo sapiens_hsa034600.40651375
112Metabolic pathways_Homo sapiens_hsa011000.40354664
113Leukocyte transendothelial migration_Homo sapiens_hsa046700.40221827
114Collecting duct acid secretion_Homo sapiens_hsa049660.39276297
115Vitamin B6 metabolism_Homo sapiens_hsa007500.38577354
116Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.38566935
117Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37981677
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37521593
119Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.36872009
120Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.36289960
121Hepatitis C_Homo sapiens_hsa051600.36222951
122Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35274654
123AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35129476
124Neurotrophin signaling pathway_Homo sapiens_hsa047220.33895368
125Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.31313309
126Cysteine and methionine metabolism_Homo sapiens_hsa002700.31237911
127Fatty acid degradation_Homo sapiens_hsa000710.30842289
128Endocytosis_Homo sapiens_hsa041440.30444573

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »