

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.51396964 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 5.18092531 |
| 3 | behavioral response to nicotine (GO:0035095) | 5.02149807 |
| 4 | cornea development in camera-type eye (GO:0061303) | 4.89584880 |
| 5 | neuron recognition (GO:0008038) | 4.88124933 |
| 6 | axon ensheathment in central nervous system (GO:0032291) | 4.63816923 |
| 7 | central nervous system myelination (GO:0022010) | 4.63816923 |
| 8 | regulation of vacuole organization (GO:0044088) | 4.59039448 |
| 9 | response to redox state (GO:0051775) | 4.56403752 |
| 10 | protein neddylation (GO:0045116) | 4.52584277 |
| 11 | nucleobase catabolic process (GO:0046113) | 4.43448937 |
| 12 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.41535463 |
| 13 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.41535463 |
| 14 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.41493040 |
| 15 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.39753499 |
| 16 | viral transcription (GO:0019083) | 4.12636998 |
| 17 | peptidyl-threonine dephosphorylation (GO:0035970) | 4.11120022 |
| 18 | axonal fasciculation (GO:0007413) | 4.09579016 |
| 19 | positive regulation of gastrulation (GO:2000543) | 4.03382533 |
| 20 | translational termination (GO:0006415) | 3.96018127 |
| 21 | response to pheromone (GO:0019236) | 3.86009054 |
| 22 | protein complex biogenesis (GO:0070271) | 3.84313235 |
| 23 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.84046926 |
| 24 | forebrain neuron development (GO:0021884) | 3.83600832 |
| 25 | regulation of autophagic vacuole assembly (GO:2000785) | 3.81674464 |
| 26 | positive regulation of neurological system process (GO:0031646) | 3.78931686 |
| 27 | chaperone-mediated protein transport (GO:0072321) | 3.60470613 |
| 28 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.59697251 |
| 29 | ATP synthesis coupled proton transport (GO:0015986) | 3.59697251 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.51129033 |
| 31 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.51129033 |
| 32 | NADH dehydrogenase complex assembly (GO:0010257) | 3.51129033 |
| 33 | epithelial cilium movement (GO:0003351) | 3.50803661 |
| 34 | ncRNA 3-end processing (GO:0043628) | 3.46735280 |
| 35 | ribosomal small subunit biogenesis (GO:0042274) | 3.46270289 |
| 36 | cochlea development (GO:0090102) | 3.45507115 |
| 37 | translational elongation (GO:0006414) | 3.40724499 |
| 38 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.36761508 |
| 39 | dendritic spine morphogenesis (GO:0060997) | 3.36017620 |
| 40 | keratinocyte development (GO:0003334) | 3.35869858 |
| 41 | nephron epithelium morphogenesis (GO:0072088) | 3.34681332 |
| 42 | nephron tubule morphogenesis (GO:0072078) | 3.34681332 |
| 43 | adaptation of signaling pathway (GO:0023058) | 3.30765912 |
| 44 | cotranslational protein targeting to membrane (GO:0006613) | 3.28349135 |
| 45 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.24791121 |
| 46 | protein targeting to ER (GO:0045047) | 3.24331387 |
| 47 | cellular ketone body metabolic process (GO:0046950) | 3.22876407 |
| 48 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 3.22152754 |
| 49 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.20096229 |
| 50 | GTP biosynthetic process (GO:0006183) | 3.20046705 |
| 51 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.19315162 |
| 52 | somite development (GO:0061053) | 3.18972944 |
| 53 | protein localization to endoplasmic reticulum (GO:0070972) | 3.18557405 |
| 54 | positive regulation of protein homooligomerization (GO:0032464) | 3.17684511 |
| 55 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.17634946 |
| 56 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.16160743 |
| 57 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.14068687 |
| 58 | transmission of nerve impulse (GO:0019226) | 3.11829104 |
| 59 | collecting duct development (GO:0072044) | 3.08015455 |
| 60 | intraciliary transport (GO:0042073) | 3.05769695 |
| 61 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.05068770 |
| 62 | respiratory electron transport chain (GO:0022904) | 3.04316228 |
| 63 | response to dietary excess (GO:0002021) | 3.01220030 |
| 64 | electron transport chain (GO:0022900) | 3.00923409 |
| 65 | respiratory chain complex IV assembly (GO:0008535) | 3.00149359 |
| 66 | viral life cycle (GO:0019058) | 2.99186188 |
| 67 | cellular protein complex disassembly (GO:0043624) | 2.99145138 |
| 68 | centrosome localization (GO:0051642) | 2.97155861 |
| 69 | protein polyglutamylation (GO:0018095) | 2.97026314 |
| 70 | protein localization to cilium (GO:0061512) | 2.96368224 |
| 71 | central nervous system neuron development (GO:0021954) | 2.95113039 |
| 72 | head development (GO:0060322) | 2.93940226 |
| 73 | peripheral nervous system axon ensheathment (GO:0032292) | 2.89210556 |
| 74 | myelination in peripheral nervous system (GO:0022011) | 2.89210556 |
| 75 | body morphogenesis (GO:0010171) | 2.88141694 |
| 76 | positive regulation of T cell apoptotic process (GO:0070234) | 2.86030062 |
| 77 | isoprenoid biosynthetic process (GO:0008299) | 2.85950918 |
| 78 | maturation of SSU-rRNA (GO:0030490) | 2.85950521 |
| 79 | ketone body metabolic process (GO:1902224) | 2.85684962 |
| 80 | embryonic body morphogenesis (GO:0010172) | 2.83443106 |
| 81 | UTP biosynthetic process (GO:0006228) | 2.83049416 |
| 82 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.81771121 |
| 83 | cholesterol biosynthetic process (GO:0006695) | 2.80225579 |
| 84 | cilium movement (GO:0003341) | 2.78753801 |
| 85 | establishment of epithelial cell polarity (GO:0090162) | 2.77805392 |
| 86 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.75945095 |
| 87 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.74731743 |
| 88 | cytochrome complex assembly (GO:0017004) | 2.72663262 |
| 89 | retinal ganglion cell axon guidance (GO:0031290) | 2.71759185 |
| 90 | CENP-A containing nucleosome assembly (GO:0034080) | 2.71603509 |
| 91 | negative regulation of glucose import (GO:0046325) | 2.71308253 |
| 92 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.71052944 |
| 93 | presynaptic membrane organization (GO:0097090) | 2.70254794 |
| 94 | cell proliferation in forebrain (GO:0021846) | 2.70146851 |
| 95 | Sertoli cell development (GO:0060009) | 2.66330534 |
| 96 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.66137230 |
| 97 | neuron migration (GO:0001764) | 2.65707050 |
| 98 | nonmotile primary cilium assembly (GO:0035058) | 2.64228720 |
| 99 | regulation of action potential (GO:0098900) | 2.63192462 |
| 100 | chromatin remodeling at centromere (GO:0031055) | 2.62128485 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 7.53976875 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 5.25697146 |
| 3 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.06180924 |
| 4 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 3.04654335 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.86628611 |
| 6 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.64774930 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.62959523 |
| 8 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.49665631 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.34013482 |
| 10 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.31170258 |
| 11 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.28057199 |
| 12 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.20919826 |
| 13 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.15340275 |
| 14 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.07851560 |
| 15 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.07413414 |
| 16 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.98609222 |
| 17 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.89493622 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.88675850 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.88526092 |
| 20 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.86669886 |
| 21 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.86107023 |
| 22 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.85970538 |
| 23 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.85970538 |
| 24 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.85635944 |
| 25 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.80826735 |
| 26 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.77375997 |
| 27 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.76681302 |
| 28 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.70626750 |
| 29 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.66637785 |
| 30 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.63821172 |
| 31 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.52429758 |
| 32 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.50546916 |
| 33 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.48554092 |
| 34 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.44972683 |
| 35 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.44513138 |
| 36 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.42714132 |
| 37 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.41676797 |
| 38 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.40906623 |
| 39 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.33816962 |
| 40 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.33416873 |
| 41 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.31004759 |
| 42 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.28579066 |
| 43 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27054747 |
| 44 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.26804738 |
| 45 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.26624070 |
| 46 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.23074561 |
| 47 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.22085372 |
| 48 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.17569301 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15961862 |
| 50 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.15036398 |
| 51 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.10082083 |
| 52 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.09696390 |
| 53 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.06815220 |
| 54 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.05825108 |
| 55 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.04870513 |
| 56 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 1.01499476 |
| 57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00897456 |
| 58 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.00346820 |
| 59 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.99423400 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.99058405 |
| 61 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.98772691 |
| 62 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.97732299 |
| 63 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.95040794 |
| 64 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.94874670 |
| 65 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.94719255 |
| 66 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.94493472 |
| 67 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.94381613 |
| 68 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.94078720 |
| 69 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.92172556 |
| 70 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90401195 |
| 71 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.89902672 |
| 72 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.88584749 |
| 73 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86755875 |
| 74 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.86632520 |
| 75 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86047050 |
| 76 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.85755047 |
| 77 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.85594558 |
| 78 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.83954666 |
| 79 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.83564829 |
| 80 | P300_19829295_ChIP-Seq_ESCs_Human | 0.82643222 |
| 81 | FUS_26573619_Chip-Seq_HEK293_Human | 0.82616993 |
| 82 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.81228764 |
| 83 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.81059693 |
| 84 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.80501904 |
| 85 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.80024418 |
| 86 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.79455058 |
| 87 | ERA_21632823_ChIP-Seq_H3396_Human | 0.78914023 |
| 88 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.78208657 |
| 89 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.78012410 |
| 90 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.77295698 |
| 91 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.76871559 |
| 92 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.75571124 |
| 93 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.75262979 |
| 94 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.74623152 |
| 95 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.74622614 |
| 96 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.74432336 |
| 97 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.73937707 |
| 98 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.73257100 |
| 99 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.72082713 |
| 100 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.72036602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 7.15237560 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.65624964 |
| 3 | MP0003787_abnormal_imprinting | 3.61028395 |
| 4 | MP0006276_abnormal_autonomic_nervous | 3.58563758 |
| 5 | MP0005423_abnormal_somatic_nervous | 3.27691585 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.92597927 |
| 7 | MP0003011_delayed_dark_adaptation | 2.82111401 |
| 8 | MP0004859_abnormal_synaptic_plasticity | 2.62526825 |
| 9 | MP0003122_maternal_imprinting | 2.61684070 |
| 10 | MP0009379_abnormal_foot_pigmentation | 2.60884920 |
| 11 | MP0002638_abnormal_pupillary_reflex | 2.50378475 |
| 12 | MP0000778_abnormal_nervous_system | 2.20871685 |
| 13 | MP0003121_genomic_imprinting | 2.06012883 |
| 14 | MP0004142_abnormal_muscle_tone | 1.99138665 |
| 15 | MP0003123_paternal_imprinting | 1.97579117 |
| 16 | MP0003646_muscle_fatigue | 1.89562558 |
| 17 | MP0000955_abnormal_spinal_cord | 1.89310651 |
| 18 | MP0009780_abnormal_chondrocyte_physiolo | 1.84073504 |
| 19 | MP0002653_abnormal_ependyma_morphology | 1.83795923 |
| 20 | MP0002163_abnormal_gland_morphology | 1.76645487 |
| 21 | MP0002876_abnormal_thyroid_physiology | 1.74297406 |
| 22 | MP0002822_catalepsy | 1.73940157 |
| 23 | MP0003329_amyloid_beta_deposits | 1.66598830 |
| 24 | MP0002272_abnormal_nervous_system | 1.65010042 |
| 25 | MP0002102_abnormal_ear_morphology | 1.62337690 |
| 26 | MP0001970_abnormal_pain_threshold | 1.56054948 |
| 27 | MP0004270_analgesia | 1.54439584 |
| 28 | MP0003635_abnormal_synaptic_transmissio | 1.52263347 |
| 29 | MP0008995_early_reproductive_senescence | 1.44028218 |
| 30 | MP0001986_abnormal_taste_sensitivity | 1.43799463 |
| 31 | MP0000049_abnormal_middle_ear | 1.40878673 |
| 32 | MP0009745_abnormal_behavioral_response | 1.39761553 |
| 33 | MP0002063_abnormal_learning/memory/cond | 1.39397668 |
| 34 | MP0002733_abnormal_thermal_nociception | 1.38651324 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.38576505 |
| 36 | MP0002837_dystrophic_cardiac_calcinosis | 1.37823177 |
| 37 | MP0002909_abnormal_adrenal_gland | 1.34827673 |
| 38 | MP0002184_abnormal_innervation | 1.31446925 |
| 39 | MP0005645_abnormal_hypothalamus_physiol | 1.29886691 |
| 40 | MP0002557_abnormal_social/conspecific_i | 1.26223466 |
| 41 | MP0001529_abnormal_vocalization | 1.25258682 |
| 42 | MP0002734_abnormal_mechanical_nocicepti | 1.24757873 |
| 43 | MP0002752_abnormal_somatic_nervous | 1.20830434 |
| 44 | MP0003942_abnormal_urinary_system | 1.19246918 |
| 45 | MP0003755_abnormal_palate_morphology | 1.15401861 |
| 46 | MP0001968_abnormal_touch/_nociception | 1.14929382 |
| 47 | MP0002882_abnormal_neuron_morphology | 1.14170568 |
| 48 | MP0002064_seizures | 1.13952579 |
| 49 | MP0008789_abnormal_olfactory_epithelium | 1.12624875 |
| 50 | MP0003136_yellow_coat_color | 1.09265553 |
| 51 | MP0004133_heterotaxia | 1.07628301 |
| 52 | MP0002572_abnormal_emotion/affect_behav | 1.07497853 |
| 53 | MP0001905_abnormal_dopamine_level | 1.07214434 |
| 54 | MP0006072_abnormal_retinal_apoptosis | 1.06583549 |
| 55 | MP0004885_abnormal_endolymph | 1.06270425 |
| 56 | MP0000631_abnormal_neuroendocrine_gland | 1.03958018 |
| 57 | MP0001486_abnormal_startle_reflex | 1.03548498 |
| 58 | MP0002152_abnormal_brain_morphology | 1.03048305 |
| 59 | MP0002735_abnormal_chemical_nociception | 1.01957196 |
| 60 | MP0005646_abnormal_pituitary_gland | 0.99402235 |
| 61 | MP0008569_lethality_at_weaning | 0.96537657 |
| 62 | MP0002067_abnormal_sensory_capabilities | 0.96233972 |
| 63 | MP0005253_abnormal_eye_physiology | 0.96181051 |
| 64 | MP0003938_abnormal_ear_development | 0.95289581 |
| 65 | MP0002229_neurodegeneration | 0.95091340 |
| 66 | MP0004145_abnormal_muscle_electrophysio | 0.95046881 |
| 67 | MP0002249_abnormal_larynx_morphology | 0.94685344 |
| 68 | MP0004742_abnormal_vestibular_system | 0.94181228 |
| 69 | MP0005379_endocrine/exocrine_gland_phen | 0.93485562 |
| 70 | MP0005195_abnormal_posterior_eye | 0.92556210 |
| 71 | MP0000026_abnormal_inner_ear | 0.92088852 |
| 72 | MP0004130_abnormal_muscle_cell | 0.91375407 |
| 73 | MP0003786_premature_aging | 0.91047696 |
| 74 | MP0005499_abnormal_olfactory_system | 0.89030435 |
| 75 | MP0005394_taste/olfaction_phenotype | 0.89030435 |
| 76 | MP0003183_abnormal_peptide_metabolism | 0.87581089 |
| 77 | MP0002139_abnormal_hepatobiliary_system | 0.87436731 |
| 78 | MP0002938_white_spotting | 0.85794600 |
| 79 | MP0009046_muscle_twitch | 0.84553666 |
| 80 | MP0000569_abnormal_digit_pigmentation | 0.82966128 |
| 81 | MP0005083_abnormal_biliary_tract | 0.80746408 |
| 82 | MP0008775_abnormal_heart_ventricle | 0.79436986 |
| 83 | MP0001963_abnormal_hearing_physiology | 0.78536900 |
| 84 | MP0005389_reproductive_system_phenotype | 0.77674073 |
| 85 | MP0001485_abnormal_pinna_reflex | 0.75585665 |
| 86 | MP0001324_abnormal_eye_pigmentation | 0.75116770 |
| 87 | MP0005503_abnormal_tendon_morphology | 0.74516009 |
| 88 | MP0004811_abnormal_neuron_physiology | 0.73471744 |
| 89 | MP0005084_abnormal_gallbladder_morpholo | 0.73313725 |
| 90 | MP0000534_abnormal_ureter_morphology | 0.73277557 |
| 91 | MP0001440_abnormal_grooming_behavior | 0.73241151 |
| 92 | MP0002066_abnormal_motor_capabilities/c | 0.72971486 |
| 93 | MP0002116_abnormal_craniofacial_bone | 0.72278374 |
| 94 | MP0004147_increased_porphyrin_level | 0.71993061 |
| 95 | MP0004924_abnormal_behavior | 0.71389086 |
| 96 | MP0005386_behavior/neurological_phenoty | 0.71389086 |
| 97 | MP0001919_abnormal_reproductive_system | 0.70567194 |
| 98 | MP0002736_abnormal_nociception_after | 0.70352052 |
| 99 | MP0000604_amyloidosis | 0.69588582 |
| 100 | MP0003948_abnormal_gas_homeostasis | 0.67379686 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Thoracolumbar scoliosis (HP:0002944) | 5.75364990 |
| 2 | Supranuclear gaze palsy (HP:0000605) | 4.39318068 |
| 3 | Myokymia (HP:0002411) | 4.24774002 |
| 4 | Reticulocytopenia (HP:0001896) | 4.15399428 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.81664529 |
| 6 | Hyperthyroidism (HP:0000836) | 3.76609555 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.54358893 |
| 8 | Pancreatic fibrosis (HP:0100732) | 3.42720270 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.31081802 |
| 10 | Pancreatic cysts (HP:0001737) | 3.22590624 |
| 11 | Acute encephalopathy (HP:0006846) | 3.18804410 |
| 12 | Papilledema (HP:0001085) | 3.13599294 |
| 13 | Agitation (HP:0000713) | 3.11138787 |
| 14 | Progressive macrocephaly (HP:0004481) | 3.10506734 |
| 15 | Mitochondrial inheritance (HP:0001427) | 3.02755527 |
| 16 | Hyperphosphatemia (HP:0002905) | 2.91646529 |
| 17 | Hepatic necrosis (HP:0002605) | 2.91482691 |
| 18 | Progressive cerebellar ataxia (HP:0002073) | 2.90342992 |
| 19 | Hyperglycinemia (HP:0002154) | 2.87007436 |
| 20 | Neonatal respiratory distress (HP:0002643) | 2.84299757 |
| 21 | Septo-optic dysplasia (HP:0100842) | 2.83767325 |
| 22 | Nephronophthisis (HP:0000090) | 2.74727631 |
| 23 | Rib fusion (HP:0000902) | 2.67719607 |
| 24 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.67463860 |
| 25 | Increased CSF lactate (HP:0002490) | 2.67165566 |
| 26 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.66452900 |
| 27 | Hepatoblastoma (HP:0002884) | 2.65802339 |
| 28 | Abnormality of midbrain morphology (HP:0002418) | 2.62882203 |
| 29 | Molar tooth sign on MRI (HP:0002419) | 2.62882203 |
| 30 | Tubular atrophy (HP:0000092) | 2.58154755 |
| 31 | Polyphagia (HP:0002591) | 2.55184534 |
| 32 | Focal seizures (HP:0007359) | 2.50751510 |
| 33 | Adrenal hypoplasia (HP:0000835) | 2.50300514 |
| 34 | Abnormality of the renal medulla (HP:0100957) | 2.46934442 |
| 35 | Abnormality of DNA repair (HP:0003254) | 2.46728245 |
| 36 | Optic disc pallor (HP:0000543) | 2.41840179 |
| 37 | Long clavicles (HP:0000890) | 2.40493463 |
| 38 | Cystic liver disease (HP:0006706) | 2.39555040 |
| 39 | True hermaphroditism (HP:0010459) | 2.37230376 |
| 40 | Congenital stationary night blindness (HP:0007642) | 2.36849445 |
| 41 | Cerebral edema (HP:0002181) | 2.34810481 |
| 42 | Abnormal biliary tract physiology (HP:0012439) | 2.32745574 |
| 43 | Bile duct proliferation (HP:0001408) | 2.32745574 |
| 44 | Medial flaring of the eyebrow (HP:0010747) | 2.31111943 |
| 45 | Optic nerve coloboma (HP:0000588) | 2.26453923 |
| 46 | Abnormality of macular pigmentation (HP:0008002) | 2.25960600 |
| 47 | Focal motor seizures (HP:0011153) | 2.25113331 |
| 48 | Short femoral neck (HP:0100864) | 2.23070175 |
| 49 | Absent thumb (HP:0009777) | 2.20823315 |
| 50 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.19047462 |
| 51 | Sclerocornea (HP:0000647) | 2.17986280 |
| 52 | Restlessness (HP:0000711) | 2.15571568 |
| 53 | Narrow forehead (HP:0000341) | 2.14569702 |
| 54 | Lissencephaly (HP:0001339) | 2.12853307 |
| 55 | Anencephaly (HP:0002323) | 2.12083733 |
| 56 | Abnormal pancreas size (HP:0012094) | 2.11505523 |
| 57 | Hypsarrhythmia (HP:0002521) | 2.10692591 |
| 58 | Postaxial foot polydactyly (HP:0001830) | 2.08473495 |
| 59 | Small hand (HP:0200055) | 2.07960018 |
| 60 | Pachygyria (HP:0001302) | 2.07750491 |
| 61 | Supernumerary spleens (HP:0009799) | 2.07576847 |
| 62 | EEG with generalized epileptiform discharges (HP:0011198) | 2.02934286 |
| 63 | Increased serum pyruvate (HP:0003542) | 2.02548114 |
| 64 | Asplenia (HP:0001746) | 1.99141727 |
| 65 | Abnormality of the renal cortex (HP:0011035) | 1.98973109 |
| 66 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.98752749 |
| 67 | Oligodactyly (hands) (HP:0001180) | 1.97700235 |
| 68 | Epileptiform EEG discharges (HP:0011182) | 1.97156389 |
| 69 | Broad alveolar ridges (HP:0000187) | 1.95534878 |
| 70 | Abnormal eating behavior (HP:0100738) | 1.94019368 |
| 71 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.91648454 |
| 72 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.91648454 |
| 73 | Holoprosencephaly (HP:0001360) | 1.90866047 |
| 74 | Hypoplastic pelvis (HP:0008839) | 1.90031896 |
| 75 | Chronic hepatic failure (HP:0100626) | 1.88794253 |
| 76 | Abnormal drinking behavior (HP:0030082) | 1.88402332 |
| 77 | Polydipsia (HP:0001959) | 1.88402332 |
| 78 | Tachypnea (HP:0002789) | 1.87631910 |
| 79 | Hypoplasia of the ulna (HP:0003022) | 1.86839731 |
| 80 | Gait imbalance (HP:0002141) | 1.85690502 |
| 81 | Growth hormone deficiency (HP:0000824) | 1.84624446 |
| 82 | Abolished electroretinogram (ERG) (HP:0000550) | 1.84145251 |
| 83 | Drooling (HP:0002307) | 1.81941625 |
| 84 | Pendular nystagmus (HP:0012043) | 1.79651871 |
| 85 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.79335266 |
| 86 | Optic nerve hypoplasia (HP:0000609) | 1.78913942 |
| 87 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.75562277 |
| 88 | Facial shape deformation (HP:0011334) | 1.75275819 |
| 89 | Potter facies (HP:0002009) | 1.75275819 |
| 90 | High anterior hairline (HP:0009890) | 1.74113564 |
| 91 | Impulsivity (HP:0100710) | 1.73432685 |
| 92 | Abnormality of the metopic suture (HP:0005556) | 1.72660275 |
| 93 | Hypoparathyroidism (HP:0000829) | 1.71521546 |
| 94 | Highly arched eyebrow (HP:0002553) | 1.71326710 |
| 95 | Hyperventilation (HP:0002883) | 1.70810296 |
| 96 | Synostosis of carpal bones (HP:0005048) | 1.69183689 |
| 97 | 3-Methylglutaconic aciduria (HP:0003535) | 1.68726929 |
| 98 | Macrocytic anemia (HP:0001972) | 1.68610328 |
| 99 | Broad-based gait (HP:0002136) | 1.67046850 |
| 100 | Irregular vertebral endplates (HP:0003301) | 1.66774985 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 5.17795134 |
| 2 | STK39 | 3.78763168 |
| 3 | PIK3CA | 3.37532979 |
| 4 | NME1 | 2.85508343 |
| 5 | MAP4K2 | 2.72783831 |
| 6 | EPHB2 | 2.43507626 |
| 7 | MARK1 | 2.29589874 |
| 8 | BCKDK | 2.28534770 |
| 9 | STK16 | 2.08622828 |
| 10 | TYRO3 | 1.97989191 |
| 11 | ICK | 1.97947149 |
| 12 | NTRK2 | 1.90398569 |
| 13 | FRK | 1.89282785 |
| 14 | MARK2 | 1.88995394 |
| 15 | TAOK3 | 1.87360884 |
| 16 | MINK1 | 1.79828183 |
| 17 | CDK19 | 1.73108253 |
| 18 | NEK1 | 1.66679612 |
| 19 | DYRK2 | 1.65377480 |
| 20 | MAP3K4 | 1.46801322 |
| 21 | ADRBK2 | 1.45573044 |
| 22 | MAP3K9 | 1.41364773 |
| 23 | GRK1 | 1.40651640 |
| 24 | MAP2K7 | 1.37999997 |
| 25 | MAP3K7 | 1.32413603 |
| 26 | BMPR1B | 1.31989372 |
| 27 | PHKG2 | 1.29119838 |
| 28 | PHKG1 | 1.29119838 |
| 29 | PNCK | 1.28854788 |
| 30 | CAMK1D | 1.27409062 |
| 31 | ARAF | 1.27046378 |
| 32 | WNK1 | 1.23053592 |
| 33 | CASK | 1.21098930 |
| 34 | LRRK2 | 1.17241747 |
| 35 | CAMK1G | 1.15663358 |
| 36 | AURKA | 1.08958862 |
| 37 | MAPK12 | 1.08739114 |
| 38 | PRKCG | 1.07512054 |
| 39 | DYRK1B | 1.03987239 |
| 40 | MAPK13 | 1.00697282 |
| 41 | CDC42BPA | 0.96059583 |
| 42 | PDK2 | 0.92013952 |
| 43 | PAK3 | 0.90757426 |
| 44 | ADRBK1 | 0.89338432 |
| 45 | OXSR1 | 0.85675135 |
| 46 | PRKCQ | 0.85187639 |
| 47 | BRAF | 0.84878546 |
| 48 | CAMK2D | 0.81461929 |
| 49 | WNK3 | 0.80872947 |
| 50 | PRKD2 | 0.80777945 |
| 51 | BRSK1 | 0.76652958 |
| 52 | STK11 | 0.74936117 |
| 53 | PRKCI | 0.74720521 |
| 54 | CDK5 | 0.73123068 |
| 55 | PIM2 | 0.72919833 |
| 56 | MAPK11 | 0.71378200 |
| 57 | CAMK1 | 0.70602914 |
| 58 | CAMKK2 | 0.70010523 |
| 59 | ABL2 | 0.68668084 |
| 60 | PRKACA | 0.68221172 |
| 61 | NTRK3 | 0.68075788 |
| 62 | INSRR | 0.65935060 |
| 63 | PRKAA1 | 0.65637460 |
| 64 | MAP2K4 | 0.63929933 |
| 65 | UHMK1 | 0.63043687 |
| 66 | CAMK2A | 0.61997564 |
| 67 | CDK14 | 0.61048098 |
| 68 | MKNK2 | 0.60168103 |
| 69 | CSNK1E | 0.59024791 |
| 70 | BCR | 0.57612315 |
| 71 | CAMK2B | 0.57005190 |
| 72 | TIE1 | 0.55765094 |
| 73 | AURKB | 0.54845794 |
| 74 | CDK15 | 0.54496595 |
| 75 | STK38L | 0.53697096 |
| 76 | RPS6KA3 | 0.52414538 |
| 77 | PLK1 | 0.52079141 |
| 78 | PAK6 | 0.50180700 |
| 79 | CDK18 | 0.49944134 |
| 80 | PRKCZ | 0.47640787 |
| 81 | TAOK1 | 0.47507073 |
| 82 | CDK11A | 0.47371919 |
| 83 | DDR2 | 0.47024740 |
| 84 | PKN1 | 0.42039773 |
| 85 | CDK3 | 0.41832840 |
| 86 | AKT1 | 0.41736066 |
| 87 | PRKCA | 0.40299626 |
| 88 | CSNK1G2 | 0.39133128 |
| 89 | PINK1 | 0.38816522 |
| 90 | PRKCE | 0.38448512 |
| 91 | CAMK2G | 0.37897769 |
| 92 | RPS6KA6 | 0.37878681 |
| 93 | SGK494 | 0.37660326 |
| 94 | SGK223 | 0.37660326 |
| 95 | DAPK3 | 0.35827955 |
| 96 | CSNK1G3 | 0.35031979 |
| 97 | MAPK14 | 0.34902631 |
| 98 | CSNK2A1 | 0.34819311 |
| 99 | CSNK2A2 | 0.32875257 |
| 100 | SYK | 0.32763629 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 4.45782146 |
| 2 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 4.07345784 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.75343848 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.53007413 |
| 5 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.38823909 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.31470370 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 3.29037173 |
| 8 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.79427275 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.45161511 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.13456322 |
| 11 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.11035513 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.06108620 |
| 13 | Peroxisome_Homo sapiens_hsa04146 | 2.04861931 |
| 14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.75288857 |
| 15 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.71196100 |
| 16 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.69823543 |
| 17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.45794741 |
| 18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.44245687 |
| 19 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.44178695 |
| 20 | Axon guidance_Homo sapiens_hsa04360 | 1.41266745 |
| 21 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.28563149 |
| 22 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.26143876 |
| 23 | Insulin secretion_Homo sapiens_hsa04911 | 1.22855411 |
| 24 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.21548610 |
| 25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.21233140 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.20182405 |
| 27 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.18666155 |
| 28 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.18292621 |
| 29 | Sulfur relay system_Homo sapiens_hsa04122 | 1.13988080 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.03831901 |
| 31 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.03123589 |
| 32 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01200175 |
| 33 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.01091785 |
| 34 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.00584241 |
| 35 | Cocaine addiction_Homo sapiens_hsa05030 | 0.98594277 |
| 36 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.96664163 |
| 37 | Homologous recombination_Homo sapiens_hsa03440 | 0.93744007 |
| 38 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.93186447 |
| 39 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.90277420 |
| 40 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.90043309 |
| 41 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.87648765 |
| 42 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.86875985 |
| 43 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.82306614 |
| 44 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.81724747 |
| 45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.81221602 |
| 46 | Protein export_Homo sapiens_hsa03060 | 0.79506418 |
| 47 | GABAergic synapse_Homo sapiens_hsa04727 | 0.78061312 |
| 48 | Retinol metabolism_Homo sapiens_hsa00830 | 0.77670513 |
| 49 | Circadian entrainment_Homo sapiens_hsa04713 | 0.76979016 |
| 50 | Olfactory transduction_Homo sapiens_hsa04740 | 0.74411939 |
| 51 | Morphine addiction_Homo sapiens_hsa05032 | 0.73558712 |
| 52 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.73210711 |
| 53 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.72607136 |
| 54 | Taste transduction_Homo sapiens_hsa04742 | 0.72035770 |
| 55 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.70978798 |
| 56 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.69446942 |
| 57 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.69436347 |
| 58 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.67157304 |
| 59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65784197 |
| 60 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.65611276 |
| 61 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.65568993 |
| 62 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.65219151 |
| 63 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.64436012 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62196828 |
| 65 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.62052814 |
| 66 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.61941540 |
| 67 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.61835155 |
| 68 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.61749209 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61655097 |
| 70 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.59004140 |
| 71 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.57402379 |
| 72 | Renin secretion_Homo sapiens_hsa04924 | 0.56603376 |
| 73 | Salivary secretion_Homo sapiens_hsa04970 | 0.55579954 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51776802 |
| 75 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.51369597 |
| 76 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.51350673 |
| 77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.50773165 |
| 78 | Basal transcription factors_Homo sapiens_hsa03022 | 0.50288104 |
| 79 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49866288 |
| 80 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.49187235 |
| 81 | RNA degradation_Homo sapiens_hsa03018 | 0.47466177 |
| 82 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.47274297 |
| 83 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.46428870 |
| 84 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.46135126 |
| 85 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.45961575 |
| 86 | Gap junction_Homo sapiens_hsa04540 | 0.44414517 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42852870 |
| 88 | RNA polymerase_Homo sapiens_hsa03020 | 0.39695414 |
| 89 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.38377760 |
| 90 | Long-term depression_Homo sapiens_hsa04730 | 0.37767493 |
| 91 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.37676594 |
| 92 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.37126320 |
| 93 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.36174006 |
| 94 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.36168255 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35912376 |
| 96 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.34740593 |
| 97 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.34075175 |
| 98 | Bile secretion_Homo sapiens_hsa04976 | 0.30816111 |
| 99 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.29171329 |
| 100 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27461149 |

