GNPNAT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.53611771
2L-phenylalanine catabolic process (GO:0006559)5.53611771
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.36913673
4L-phenylalanine metabolic process (GO:0006558)5.36913673
5glycine metabolic process (GO:0006544)5.08324050
6aromatic amino acid family catabolic process (GO:0009074)4.82659661
7serine family amino acid biosynthetic process (GO:0009070)4.79002956
8serine family amino acid catabolic process (GO:0009071)4.73489288
9nuclear pore complex assembly (GO:0051292)4.69017986
10cysteine metabolic process (GO:0006534)4.49988692
11serine family amino acid metabolic process (GO:0009069)4.44348947
12purine nucleobase biosynthetic process (GO:0009113)4.40568497
13indole-containing compound catabolic process (GO:0042436)4.30595848
14indolalkylamine catabolic process (GO:0046218)4.30595848
15tryptophan catabolic process (GO:0006569)4.30595848
16nuclear pore organization (GO:0006999)4.21506241
17establishment of integrated proviral latency (GO:0075713)4.16483634
18DNA unwinding involved in DNA replication (GO:0006268)4.15289470
19L-serine metabolic process (GO:0006563)4.10711544
20glyoxylate metabolic process (GO:0046487)4.06380119
21sulfur amino acid catabolic process (GO:0000098)4.06199785
22tryptophan metabolic process (GO:0006568)4.06133972
23kynurenine metabolic process (GO:0070189)3.98316399
24nucleobase biosynthetic process (GO:0046112)3.94250332
25folic acid metabolic process (GO:0046655)3.93296379
26bile acid biosynthetic process (GO:0006699)3.87953403
27triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.86494448
28homocysteine metabolic process (GO:0050667)3.80683062
29urea metabolic process (GO:0019627)3.79514404
30urea cycle (GO:0000050)3.79514404
31aromatic amino acid family metabolic process (GO:0009072)3.78441506
32negative regulation of fibrinolysis (GO:0051918)3.69065304
33regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.65491730
34protein complex localization (GO:0031503)3.59795057
35protein carboxylation (GO:0018214)3.58849636
36peptidyl-glutamic acid carboxylation (GO:0017187)3.58849636
37mitotic sister chromatid segregation (GO:0000070)3.57137819
38regulation of translational fidelity (GO:0006450)3.56982391
39regulation of fibrinolysis (GO:0051917)3.56762157
40nitrogen cycle metabolic process (GO:0071941)3.54937370
41mitotic chromosome condensation (GO:0007076)3.54432427
42nucleobase-containing small molecule interconversion (GO:0015949)3.53688179
43DNA strand elongation involved in DNA replication (GO:0006271)3.51168778
44regulation of protein activation cascade (GO:2000257)3.50878129
45DNA strand elongation (GO:0022616)3.48264050
46amino-acid betaine metabolic process (GO:0006577)3.46992623
47protein localization to kinetochore (GO:0034501)3.45051142
48COPI coating of Golgi vesicle (GO:0048205)3.42360792
49Golgi transport vesicle coating (GO:0048200)3.42360792
50bile acid metabolic process (GO:0008206)3.41992498
51formation of translation preinitiation complex (GO:0001731)3.40435760
52alpha-amino acid catabolic process (GO:1901606)3.39857401
53high-density lipoprotein particle remodeling (GO:0034375)3.39056872
54S-adenosylmethionine metabolic process (GO:0046500)3.38923921
55sister chromatid segregation (GO:0000819)3.36542726
56bile acid and bile salt transport (GO:0015721)3.34620992
57pore complex assembly (GO:0046931)3.34456369
58cellular protein complex localization (GO:0034629)3.31618305
59protein localization to chromosome, centromeric region (GO:0071459)3.29142824
60regulation of complement activation (GO:0030449)3.26868717
61regulation of cholesterol esterification (GO:0010872)3.26706183
62amino acid salvage (GO:0043102)3.26683263
63L-methionine salvage (GO:0071267)3.26683263
64L-methionine biosynthetic process (GO:0071265)3.26683263
65sulfur amino acid biosynthetic process (GO:0000097)3.25596282
66metaphase plate congression (GO:0051310)3.24645693
67aldehyde catabolic process (GO:0046185)3.24421275
68cellular biogenic amine catabolic process (GO:0042402)3.21528284
69amine catabolic process (GO:0009310)3.21528284
70tyrosine metabolic process (GO:0006570)3.20962892
71IMP biosynthetic process (GO:0006188)3.19668543
72complement activation, alternative pathway (GO:0006957)3.19502444
73proteasome assembly (GO:0043248)3.18841631
74urate metabolic process (GO:0046415)3.16451532
75telomere maintenance via semi-conservative replication (GO:0032201)3.15602768
76cellular amino acid catabolic process (GO:0009063)3.15431092
77imidazole-containing compound metabolic process (GO:0052803)3.15182419
78* nucleotide-sugar biosynthetic process (GO:0009226)3.13293947
79ribosome assembly (GO:0042255)3.13283636
80establishment of viral latency (GO:0019043)3.12443410
81sulfur amino acid metabolic process (GO:0000096)3.12255329
82cellular glucuronidation (GO:0052695)3.10308413
83regulation of centriole replication (GO:0046599)3.07851432
84heme transport (GO:0015886)3.06249946
85pantothenate metabolic process (GO:0015939)3.05585782
86indolalkylamine metabolic process (GO:0006586)3.04956398
87folic acid-containing compound metabolic process (GO:0006760)3.04032799
88mitotic sister chromatid cohesion (GO:0007064)3.03920416
89one-carbon metabolic process (GO:0006730)3.03847359
90folic acid-containing compound biosynthetic process (GO:0009396)3.01688749
91acylglycerol homeostasis (GO:0055090)3.00898327
92triglyceride homeostasis (GO:0070328)3.00898327
93DNA replication checkpoint (GO:0000076)2.98118181
94IMP metabolic process (GO:0046040)2.97022809
95COPII vesicle coating (GO:0048208)2.96613584
96tetrahydrofolate metabolic process (GO:0046653)2.96031768
97heterochromatin organization (GO:0070828)2.95664639
98CENP-A containing nucleosome assembly (GO:0034080)2.94426570
99protein-lipid complex remodeling (GO:0034368)2.93148818
100macromolecular complex remodeling (GO:0034367)2.93148818
101plasma lipoprotein particle remodeling (GO:0034369)2.93148818
102mitotic nuclear envelope disassembly (GO:0007077)2.92365018
103DNA deamination (GO:0045006)2.91413181
104alpha-linolenic acid metabolic process (GO:0036109)2.89089289
105methionine metabolic process (GO:0006555)2.88187966
106proline biosynthetic process (GO:0006561)2.87844232
107lysine metabolic process (GO:0006553)2.87742618
108lysine catabolic process (GO:0006554)2.87742618
109regulation of triglyceride catabolic process (GO:0010896)2.87617367
110benzene-containing compound metabolic process (GO:0042537)2.86062176
111paraxial mesoderm development (GO:0048339)2.84923372
112pteridine-containing compound metabolic process (GO:0042558)2.84247863
113blood coagulation, intrinsic pathway (GO:0007597)2.83801092
114negative regulation of sterol transport (GO:0032372)2.83735419
115negative regulation of cholesterol transport (GO:0032375)2.83735419
116mitotic metaphase plate congression (GO:0007080)2.81727502
117pteridine-containing compound biosynthetic process (GO:0042559)2.80622000
118regulation of translational termination (GO:0006449)2.80165404
119chromatin remodeling at centromere (GO:0031055)2.80158134
120regulation of bile acid biosynthetic process (GO:0070857)2.79223438
121fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.79099626
122telomere maintenance via recombination (GO:0000722)2.78930587
123reverse cholesterol transport (GO:0043691)2.78884205
124regulation of mitotic spindle organization (GO:0060236)2.78471093
125ribosomal large subunit biogenesis (GO:0042273)2.78064740
126establishment of chromosome localization (GO:0051303)2.77979645
127DNA replication initiation (GO:0006270)2.77780462
128negative regulation of fatty acid biosynthetic process (GO:0045717)2.77041589
129negative regulation of DNA repair (GO:0045738)2.77038935
130coenzyme catabolic process (GO:0009109)2.76087518
131mitotic recombination (GO:0006312)2.73888882
132regulation of spindle organization (GO:0090224)2.73303336
133organic acid catabolic process (GO:0016054)2.72985228
134carboxylic acid catabolic process (GO:0046395)2.72985228
135folic acid transport (GO:0015884)2.72276219
136uronic acid metabolic process (GO:0006063)2.71965966
137glucuronate metabolic process (GO:0019585)2.71965966
138nuclear envelope disassembly (GO:0051081)2.69279013
139membrane disassembly (GO:0030397)2.69279013
140regulation of centrosome cycle (GO:0046605)2.68187956
141arginine metabolic process (GO:0006525)2.66309583
142aspartate family amino acid metabolic process (GO:0009066)2.66027607
143rRNA modification (GO:0000154)2.65505575
144double-strand break repair via nonhomologous end joining (GO:0006303)2.65439726
145non-recombinational repair (GO:0000726)2.65439726
146tRNA aminoacylation for protein translation (GO:0006418)2.64806841
147anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.64387488
148maturation of SSU-rRNA (GO:0030490)2.64066130
149cellular ketone body metabolic process (GO:0046950)2.63911282
150fibrinolysis (GO:0042730)2.63863931
151alpha-amino acid biosynthetic process (GO:1901607)2.63792711
152ribosome biogenesis (GO:0042254)2.63681022
153positive regulation of chromosome segregation (GO:0051984)2.63324793
154ribonucleoprotein complex biogenesis (GO:0022613)2.62527204
155NAD biosynthetic process (GO:0009435)2.62489794
156negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.61393048
157regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.60631044
158regulation of chromosome segregation (GO:0051983)2.60287138
159amino acid activation (GO:0043038)2.59776778
160tRNA aminoacylation (GO:0043039)2.59776778
161DNA duplex unwinding (GO:0032508)2.57022231
162spindle checkpoint (GO:0031577)2.50688200
163ventricular cardiac muscle cell development (GO:0055015)2.49595516
164negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.48927932
165negative regulation of ligase activity (GO:0051352)2.48927932
166DNA geometric change (GO:0032392)2.48670222
167maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.46180791
168chromosome condensation (GO:0030261)2.43959297
169desmosome organization (GO:0002934)2.43520533
170positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.42891510
171G1/S transition of mitotic cell cycle (GO:0000082)2.42763875
172cell cycle G1/S phase transition (GO:0044843)2.42763875
173regulation of centrosome duplication (GO:0010824)2.40798811
174protein maturation by protein folding (GO:0022417)2.40466961
175notochord development (GO:0030903)2.40306906
176DNA replication-independent nucleosome organization (GO:0034724)2.39282605
177DNA replication-independent nucleosome assembly (GO:0006336)2.39282605
178histone exchange (GO:0043486)2.38528894
179mitotic spindle checkpoint (GO:0071174)2.35952380
180regulation of translational elongation (GO:0006448)2.35937613
181negative regulation of chromosome segregation (GO:0051985)2.34373943
182protein retention in ER lumen (GO:0006621)2.33522051
183viral mRNA export from host cell nucleus (GO:0046784)2.33146345
184regulation of sister chromatid cohesion (GO:0007063)2.32700512
185negative regulation of mitotic sister chromatid separation (GO:2000816)2.29714927
186negative regulation of sister chromatid segregation (GO:0033046)2.29714927
187negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.29714927
188negative regulation of mitotic sister chromatid segregation (GO:0033048)2.29714927

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.49028833
2* EGR1_23403033_ChIP-Seq_LIVER_Mouse3.85060224
3* RXR_22158963_ChIP-Seq_LIVER_Mouse3.80602745
4E2F7_22180533_ChIP-Seq_HELA_Human3.68726847
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.66772496
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.64799448
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.56848455
8MYC_18555785_ChIP-Seq_MESCs_Mouse3.54740071
9PPARA_22158963_ChIP-Seq_LIVER_Mouse3.37518157
10GABP_17652178_ChIP-ChIP_JURKAT_Human3.11704529
11CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.08135297
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.05543915
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.79894380
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.76912372
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.68532777
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.64287251
17* LXR_22158963_ChIP-Seq_LIVER_Mouse2.57739224
18SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.48367710
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.44321151
20* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.33288707
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.20366945
22MYC_19079543_ChIP-ChIP_MESCs_Mouse2.13117266
23PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.08322207
24VDR_23849224_ChIP-Seq_CD4+_Human2.06172688
25AR_21909140_ChIP-Seq_LNCAP_Human2.05292488
26* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.04001576
27TP63_17297297_ChIP-ChIP_HaCaT_Human2.03533064
28DCP1A_22483619_ChIP-Seq_HELA_Human2.01593811
29CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.01052983
30FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.95681503
31NELFA_20434984_ChIP-Seq_ESCs_Mouse1.95159972
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.94498645
33ESR1_15608294_ChIP-ChIP_MCF-7_Human1.91963435
34FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.90424480
35HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.88298214
36E2F4_17652178_ChIP-ChIP_JURKAT_Human1.87579590
37HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.80769775
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.73590633
39GABP_19822575_ChIP-Seq_HepG2_Human1.72414456
40FOXP3_21729870_ChIP-Seq_TREG_Human1.72000786
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71889494
42PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.70956738
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.67867468
44PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.67341664
45HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.63307299
46XRN2_22483619_ChIP-Seq_HELA_Human1.63232843
47MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.63048549
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.55043428
49CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.53336440
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.52132976
51HIF1A_21447827_ChIP-Seq_MCF-7_Human1.52124302
52* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.51682829
53DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.50346750
54ELK1_19687146_ChIP-ChIP_HELA_Human1.43716721
55STAT3_1855785_ChIP-Seq_MESCs_Mouse1.42203110
56NANOG_18555785_ChIP-Seq_MESCs_Mouse1.33513244
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.32689781
58SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.31582776
59TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30749502
60NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.29611747
61* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.28804160
62* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.28782325
63HOXB4_20404135_ChIP-ChIP_EML_Mouse1.28636171
64KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.28385785
65STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.28211762
66* CHD1_26751641_Chip-Seq_LNCaP_Human1.26913515
67SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.22809613
68MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.22659830
69* KAP1_22055183_ChIP-Seq_ESCs_Mouse1.21791911
70THAP11_20581084_ChIP-Seq_MESCs_Mouse1.21610389
71SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.21490527
72SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.21490527
73CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.21327076
74HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.21030097
75KDM5A_27292631_Chip-Seq_BREAST_Human1.20050243
76TTF2_22483619_ChIP-Seq_HELA_Human1.18639725
77YY1_21170310_ChIP-Seq_MESCs_Mouse1.18351647
78PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18013502
79E2F1_21310950_ChIP-Seq_MCF-7_Human1.15697828
80NOTCH1_21737748_ChIP-Seq_TLL_Human1.14976299
81POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.14711561
82ESR1_20079471_ChIP-ChIP_T-47D_Human1.14045699
83ELF5_23300383_ChIP-Seq_T47D_Human1.13606297
84ERG_20887958_ChIP-Seq_HPC-7_Mouse1.12933237
85FOXM1_23109430_ChIP-Seq_U2OS_Human1.10722611
86ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.07524493
87ATF3_27146783_Chip-Seq_COLON_Human1.06342366
88TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.05175153
89CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.05079414
90NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.05068248
91FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.03842505
92ELK1_22589737_ChIP-Seq_MCF10A_Human1.03679018
93ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.02337254
94TRIM28_21343339_ChIP-Seq_HEK293_Human1.02302725
95CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.00984970
96* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.99372322
97FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.99371053
98GATA6_25053715_ChIP-Seq_YYC3_Human0.96316240
99BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95587553
100RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95543774
101ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95261720
102NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.95135107
103* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.94865646
104KLF4_18555785_ChIP-Seq_MESCs_Mouse0.94319146
105YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.93964802
106SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93760323
107ZNF263_19887448_ChIP-Seq_K562_Human0.93191772
108KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.93170987
109POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.93101429
110TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.91934979
111* SOX17_20123909_ChIP-Seq_XEN_Mouse0.90687644
112ESR1_21235772_ChIP-Seq_MCF-7_Human0.90069052
113PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.89551858
114CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.88605915
115CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88229062
116NANOG_16153702_ChIP-ChIP_HESCs_Human0.86221117
117GATA1_22025678_ChIP-Seq_K562_Human0.83146408
118IRF1_19129219_ChIP-ChIP_H3396_Human0.82980867
119MYC_18940864_ChIP-ChIP_HL60_Human0.81921082
120* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.78387505
121* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.77627524
122TFEB_21752829_ChIP-Seq_HELA_Human0.77251883
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.76985168
124* SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.76622705
125HTT_18923047_ChIP-ChIP_STHdh_Human0.75632326
126RXRA_24833708_ChIP-Seq_LIVER_Mouse0.75320622
127CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.74434211
128TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.73861369
129SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.72639705
130CLOCK_20551151_ChIP-Seq_293T_Human0.72332407
131* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.71095521
132SALL4_18804426_ChIP-ChIP_XEN_Mouse0.70924193
133NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.70688817
134MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.70407720

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system6.66064985
2MP0005360_urolithiasis5.63292426
3MP0005085_abnormal_gallbladder_physiolo5.24180964
4MP0005365_abnormal_bile_salt5.15882363
5MP0003806_abnormal_nucleotide_metabolis4.52882556
6MP0008875_abnormal_xenobiotic_pharmacok4.03975680
7MP0003941_abnormal_skin_development3.24722672
8MP0003693_abnormal_embryo_hatching2.92216221
9MP0010352_gastrointestinal_tract_polyps2.83456382
10MP0009840_abnormal_foam_cell2.83287967
11MP0003252_abnormal_bile_duct2.57879629
12MP0003195_calcinosis2.51772375
13MP0003950_abnormal_plasma_membrane2.50977288
14MP0005332_abnormal_amino_acid2.50322160
15MP0001666_abnormal_nutrient_absorption2.48541758
16MP0010329_abnormal_lipoprotein_level2.42711866
17MP0003718_maternal_effect2.35856316
18MP0010234_abnormal_vibrissa_follicle2.31121549
19MP0008438_abnormal_cutaneous_collagen2.22093201
20MP0003186_abnormal_redox_activity2.15869073
21MP0003566_abnormal_cell_adhesion2.15366210
22MP0001764_abnormal_homeostasis2.13030478
23MP0005083_abnormal_biliary_tract2.11873356
24MP0004272_abnormal_basement_membrane2.11441330
25MP0004957_abnormal_blastocyst_morpholog2.06810424
26MP0002877_abnormal_melanocyte_morpholog2.05904338
27MP0004019_abnormal_vitamin_homeostasis2.01049487
28MP0002796_impaired_skin_barrier1.94113518
29MP0000537_abnormal_urethra_morphology1.94049118
30MP0004233_abnormal_muscle_weight1.91895295
31MP0009780_abnormal_chondrocyte_physiolo1.78653520
32MP0003868_abnormal_feces_composition1.77078443
33MP0005451_abnormal_body_composition1.74425010
34MP0000609_abnormal_liver_physiology1.72663893
35MP0009697_abnormal_copulation1.70822839
36MP0005319_abnormal_enzyme/_coenzyme1.63340176
37MP0002138_abnormal_hepatobiliary_system1.62156570
38MP0003191_abnormal_cellular_cholesterol1.61102101
39MP0005501_abnormal_skin_physiology1.60859955
40MP0005623_abnormal_meninges_morphology1.51987064
41MP0003111_abnormal_nucleus_morphology1.51400054
42MP0003315_abnormal_perineum_morphology1.51302748
43MP0010030_abnormal_orbit_morphology1.50192565
44MP0010094_abnormal_chromosome_stability1.50077092
45MP0003890_abnormal_embryonic-extraembry1.45023744
46MP0002254_reproductive_system_inflammat1.44942156
47MP0002060_abnormal_skin_morphology1.44126946
48MP0002118_abnormal_lipid_homeostasis1.43479302
49MP0000762_abnormal_tongue_morphology1.39293736
50MP0006036_abnormal_mitochondrial_physio1.36437162
51MP0005220_abnormal_exocrine_pancreas1.35752552
52* MP0003984_embryonic_growth_retardation1.35380992
53MP0003077_abnormal_cell_cycle1.33597372
54MP0005408_hypopigmentation1.32632332
55MP0005084_abnormal_gallbladder_morpholo1.31427474
56MP0000627_abnormal_mammary_gland1.31019368
57MP0005257_abnormal_intraocular_pressure1.29390927
58* MP0002085_abnormal_embryonic_tissue1.29073587
59MP0001881_abnormal_mammary_gland1.26734349
60* MP0002084_abnormal_developmental_patter1.26682237
61MP0003786_premature_aging1.25298742
62MP0010307_abnormal_tumor_latency1.25060328
63MP0009643_abnormal_urine_homeostasis1.24460804
64MP0008058_abnormal_DNA_repair1.22317080
65MP0003937_abnormal_limbs/digits/tail_de1.21428573
66* MP0002086_abnormal_extraembryonic_tissu1.21193575
67MP0000598_abnormal_liver_morphology1.18952118
68MP0008057_abnormal_DNA_replication1.15119142
69MP0002697_abnormal_eye_size1.13653686
70MP0004185_abnormal_adipocyte_glucose1.12639598
71MP0005076_abnormal_cell_differentiation1.10290900
72MP0001849_ear_inflammation1.08835952
73MP0005395_other_phenotype1.08455581
74MP0001542_abnormal_bone_strength1.05230994
75MP0002160_abnormal_reproductive_system1.05190176
76MP0005636_abnormal_mineral_homeostasis1.04278414
77MP0008932_abnormal_embryonic_tissue1.03879956
78MP0000467_abnormal_esophagus_morphology1.02447043
79MP0003656_abnormal_erythrocyte_physiolo1.02419009
80MP0004197_abnormal_fetal_growth/weight/1.01843237
81MP0005584_abnormal_enzyme/coenzyme_acti0.98523658
82MP0000579_abnormal_nail_morphology0.95888035
83MP0008260_abnormal_autophagy0.95472182
84MP0001216_abnormal_epidermal_layer0.94801461
85MP0001661_extended_life_span0.94491619
86MP0008007_abnormal_cellular_replicative0.93619751
87MP0006035_abnormal_mitochondrial_morpho0.92282857
88MP0004264_abnormal_extraembryonic_tissu0.91865138
89MP0002098_abnormal_vibrissa_morphology0.89476140
90MP0002132_abnormal_respiratory_system0.86891734
91MP0009379_abnormal_foot_pigmentation0.86401243
92MP0004782_abnormal_surfactant_physiolog0.86394017
93MP0010678_abnormal_skin_adnexa0.85418940
94MP0008469_abnormal_protein_level0.85372446
95MP0001730_embryonic_growth_arrest0.84780661
96MP0001293_anophthalmia0.84127702
97MP0005647_abnormal_sex_gland0.84059577
98MP0003011_delayed_dark_adaptation0.83225095
99MP0002111_abnormal_tail_morphology0.82197646
100MP0009763_increased_sensitivity_to0.80801762
101MP0010771_integument_phenotype0.79669949
102MP0001299_abnormal_eye_distance/0.79509252
103MP0001346_abnormal_lacrimal_gland0.79417132
104MP0003755_abnormal_palate_morphology0.79374327
105MP0000428_abnormal_craniofacial_morphol0.79157458
106MP0005376_homeostasis/metabolism_phenot0.78781605
107MP0001756_abnormal_urination0.78441359
108MP0002876_abnormal_thyroid_physiology0.77293230
109MP0003942_abnormal_urinary_system0.77263913
110MP0003453_abnormal_keratinocyte_physiol0.76750769
111MP0001727_abnormal_embryo_implantation0.76281048
112MP0001286_abnormal_eye_development0.75692883
113MP0003123_paternal_imprinting0.72854196
114MP0005275_abnormal_skin_tensile0.72839545
115MP0005266_abnormal_metabolism0.72422694
116MP0009333_abnormal_splenocyte_physiolog0.72089792
117MP0002092_abnormal_eye_morphology0.72062595
118MP0003724_increased_susceptibility_to0.71568266
119MP0005197_abnormal_uvea_morphology0.71322010
120MP0001119_abnormal_female_reproductive0.70704407
121MP0005621_abnormal_cell_physiology0.70486164
122MP0000313_abnormal_cell_death0.69437057
123MP0003936_abnormal_reproductive_system0.69351999
124MP0009765_abnormal_xenobiotic_induced0.68348452
125MP0009642_abnormal_blood_homeostasis0.68085555
126MP0001915_intracranial_hemorrhage0.68022596
127MP0000432_abnormal_head_morphology0.67734326
128MP0000427_abnormal_hair_cycle0.67709773
129MP0003385_abnormal_body_wall0.67522201
130MP0002396_abnormal_hematopoietic_system0.67265480
131MP0009672_abnormal_birth_weight0.65481066
132MP0005670_abnormal_white_adipose0.63464399
133MP0000653_abnormal_sex_gland0.58694224
134MP0005389_reproductive_system_phenotype0.58424700
135MP0002210_abnormal_sex_determination0.58020170
136MP0008873_increased_physiological_sensi0.57873652
137MP0009053_abnormal_anal_canal0.56746113
138MP0001145_abnormal_male_reproductive0.55752670
139MP0001919_abnormal_reproductive_system0.55077642
140MP0000490_abnormal_crypts_of0.54438273
141MP0009384_cardiac_valve_regurgitation0.54055055
142MP0003699_abnormal_female_reproductive0.53996844
143MP0009764_decreased_sensitivity_to0.53720965
144MP0002019_abnormal_tumor_incidence0.52892696
145MP0001853_heart_inflammation0.51904713
146MP0000358_abnormal_cell_content/0.51468056
147MP0005058_abnormal_lysosome_morphology0.50506428
148MP0003705_abnormal_hypodermis_morpholog0.50028176
149MP0002136_abnormal_kidney_physiology0.49711982
150* MP0005380_embryogenesis_phenotype0.49043594
151* MP0001672_abnormal_embryogenesis/_devel0.49043594
152MP0001929_abnormal_gametogenesis0.48910466
153* MP0000350_abnormal_cell_proliferation0.48574168
154* MP0002080_prenatal_lethality0.48129154
155MP0003221_abnormal_cardiomyocyte_apopto0.48126688
156MP0001697_abnormal_embryo_size0.48028970
157MP0001243_abnormal_dermal_layer0.47851711
158MP0010368_abnormal_lymphatic_system0.47237062
159MP0002078_abnormal_glucose_homeostasis0.46746756
160MP0005023_abnormal_wound_healing0.41525036
161* MP0002088_abnormal_embryonic_growth/wei0.39612585

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)6.16580109
2Intrahepatic cholestasis (HP:0001406)5.45663923
3Hyperglycinemia (HP:0002154)5.32387857
4Abnormality of monocarboxylic acid metabolism (HP:0010996)5.28799048
5Prolonged partial thromboplastin time (HP:0003645)5.06999786
6Hypobetalipoproteinemia (HP:0003563)5.04809541
7Deep venous thrombosis (HP:0002625)4.56464358
8Hyperglycinuria (HP:0003108)4.45659590
9Xanthomatosis (HP:0000991)4.30406560
10Abnormality of glycine metabolism (HP:0010895)4.22238479
11Abnormality of serine family amino acid metabolism (HP:0010894)4.22238479
12Abnormality of serum amino acid levels (HP:0003112)3.90307361
13Hyperlipoproteinemia (HP:0010980)3.89398184
14Abnormality of methionine metabolism (HP:0010901)3.72366472
15Hypolipoproteinemia (HP:0010981)3.64755187
16Chromosomal breakage induced by crosslinking agents (HP:0003221)3.64594561
17Premature rupture of membranes (HP:0001788)3.61895310
18Hyperammonemia (HP:0001987)3.60771294
19Abnormality of pyrimidine metabolism (HP:0004353)3.56733337
20Abnormality of aspartate family amino acid metabolism (HP:0010899)3.51872920
21Chromsome breakage (HP:0040012)3.50208294
22Abnormality of the intrinsic pathway (HP:0010989)3.49011180
23Fat malabsorption (HP:0002630)3.45328410
24Abnormality of sulfur amino acid metabolism (HP:0004339)3.44872504
25Abnormality of the common coagulation pathway (HP:0010990)3.33210366
26Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.23529486
27Hypoglycemic coma (HP:0001325)3.23527284
28Joint hemorrhage (HP:0005261)3.14925896
29Complement deficiency (HP:0004431)3.11955237
30Abnormality of fatty-acid metabolism (HP:0004359)3.06334662
31Lethargy (HP:0001254)3.05629509
32Conjugated hyperbilirubinemia (HP:0002908)2.99959637
33Birth length less than 3rd percentile (HP:0003561)2.99574493
34Gout (HP:0001997)2.95776738
35Hypoalphalipoproteinemia (HP:0003233)2.95454840
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.86159278
37Abnormality of glutamine family amino acid metabolism (HP:0010902)2.84770835
38Steatorrhea (HP:0002570)2.84471958
39Microglossia (HP:0000171)2.79520992
40Delayed CNS myelination (HP:0002188)2.76863872
41Abnormality of dicarboxylic acid metabolism (HP:0010995)2.73707984
42Dicarboxylic aciduria (HP:0003215)2.73707984
43Spontaneous abortion (HP:0005268)2.71848047
44Ketosis (HP:0001946)2.70362087
45Abnormality of nucleobase metabolism (HP:0010932)2.69754278
46Cerebral edema (HP:0002181)2.68244009
47Breast hypoplasia (HP:0003187)2.62293780
48Insidious onset (HP:0003587)2.60416289
49Termporal pattern (HP:0011008)2.60416289
50Asymmetry of the thorax (HP:0001555)2.57374773
51Abnormality of the umbilical cord (HP:0010881)2.56545227
52Epidermoid cyst (HP:0200040)2.49805731
53Megaloblastic anemia (HP:0001889)2.45004997
54Reduced antithrombin III activity (HP:0001976)2.44103464
55Abnormalities of placenta or umbilical cord (HP:0001194)2.44063984
56Selective tooth agenesis (HP:0001592)2.43502384
57Hyperbilirubinemia (HP:0002904)2.40746550
58Oral leukoplakia (HP:0002745)2.37519871
59Nausea (HP:0002018)2.35863503
60Abnormality of the preputium (HP:0100587)2.33652878
61Abnormality of complement system (HP:0005339)2.32607304
62Right ventricular cardiomyopathy (HP:0011663)2.31423763
63Protrusio acetabuli (HP:0003179)2.29278262
64Hyperglycemia (HP:0003074)2.27632381
65Generalized aminoaciduria (HP:0002909)2.27292521
66Ankle contracture (HP:0006466)2.26405472
67Abnormality of purine metabolism (HP:0004352)2.26264749
68Deviation of the thumb (HP:0009603)2.24951217
69Abnormal cartilage morphology (HP:0002763)2.24761417
70Meckel diverticulum (HP:0002245)2.24427836
71Spastic paraparesis (HP:0002313)2.22314482
72Osteolytic defects of the hand bones (HP:0009699)2.21835251
73Osteolytic defects of the phalanges of the hand (HP:0009771)2.21835251
74Irritability (HP:0000737)2.19727960
75Abnormal umbilical cord blood vessels (HP:0011403)2.17296175
76Single umbilical artery (HP:0001195)2.17296175
77Abnormality of the fetal cardiovascular system (HP:0010948)2.17296175
78Metabolic acidosis (HP:0001942)2.16915221
79Hepatic necrosis (HP:0002605)2.15438941
80Pterygium (HP:0001059)2.13096426
81Hepatocellular carcinoma (HP:0001402)2.10891371
82Nephroblastoma (Wilms tumor) (HP:0002667)2.10664072
83Glycosuria (HP:0003076)2.10568323
84Abnormality of urine glucose concentration (HP:0011016)2.10568323
85Proximal tubulopathy (HP:0000114)2.10567196
86Rough bone trabeculation (HP:0100670)2.09019233
87Secondary amenorrhea (HP:0000869)2.08916722
88Abnormality of the ileum (HP:0001549)2.07290358
89Hypercholesterolemia (HP:0003124)2.06363307
90Embryonal renal neoplasm (HP:0011794)2.06113070
91Impulsivity (HP:0100710)2.05233232
92Sparse eyelashes (HP:0000653)2.05072079
93Increased nuchal translucency (HP:0010880)2.04056549
94Trismus (HP:0000211)2.03545833
95Amniotic constriction ring (HP:0009775)2.03132121
96Abnormality of placental membranes (HP:0011409)2.03132121
973-Methylglutaconic aciduria (HP:0003535)2.02899409
98Carpal bone hypoplasia (HP:0001498)2.02247222
99CNS demyelination (HP:0007305)2.00263203
100Abnormality of chromosome stability (HP:0003220)1.99970375
101Renal cortical cysts (HP:0000803)1.99964307
102Cardiovascular calcification (HP:0011915)1.99193929
103Acute encephalopathy (HP:0006846)1.97683624
104Brushfield spots (HP:0001088)1.97119175
105Reduced subcutaneous adipose tissue (HP:0003758)1.95948381
106Multiple enchondromatosis (HP:0005701)1.95020647
107Beaking of vertebral bodies (HP:0004568)1.94303808
108Proximal placement of thumb (HP:0009623)1.93671581
109Deep philtrum (HP:0002002)1.90514324
110Septate vagina (HP:0001153)1.89965313
111Abnormality of the anterior horn cell (HP:0006802)1.89375513
112Degeneration of anterior horn cells (HP:0002398)1.89375513
113Myocardial infarction (HP:0001658)1.89129563
114Opisthotonus (HP:0002179)1.89009625
115Vascular calcification (HP:0004934)1.88205571
116Increased purine levels (HP:0004368)1.87761313
117Hyperuricemia (HP:0002149)1.87761313
118Abnormal spermatogenesis (HP:0008669)1.87416847
119Unilateral renal agenesis (HP:0000122)1.86476607
120Cerebral hypomyelination (HP:0006808)1.85753967
121Progressive muscle weakness (HP:0003323)1.84756421
122Spinal cord compression (HP:0002176)1.83811200
123Spinal cord lesions (HP:0100561)1.82729248
124Syringomyelia (HP:0003396)1.82729248
125Increased serum pyruvate (HP:0003542)1.82107066
126Abnormality of glycolysis (HP:0004366)1.82107066
127Abnormality of carpal bone ossification (HP:0006257)1.81381738
128Pancreatitis (HP:0001733)1.80648539
129Malnutrition (HP:0004395)1.80576364
130Spinal rigidity (HP:0003306)1.80335311
131Sparse lateral eyebrow (HP:0005338)1.80231352
132Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.80138060
133Increased serum lactate (HP:0002151)1.79588282
134Vomiting (HP:0002013)1.78390659
135Prolonged neonatal jaundice (HP:0006579)1.78277323
136Ependymoma (HP:0002888)1.77576692
137Abnormality of the distal phalanges of the toes (HP:0010182)1.77013910
138Elbow flexion contracture (HP:0002987)1.75472481
139Abnormality of alanine metabolism (HP:0010916)1.75189698
140Hyperalaninemia (HP:0003348)1.75189698
141Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.75189698
142Aplasia/Hypoplasia of the uvula (HP:0010293)1.75136688
143Short nail (HP:0001799)1.74819779
144Progressive external ophthalmoplegia (HP:0000590)1.72610722
145Absent radius (HP:0003974)1.71824822
146Spastic diplegia (HP:0001264)1.71532218
147Ketoacidosis (HP:0001993)1.71485123
148Fibular aplasia (HP:0002990)1.71347188
149Hypoglycemic seizures (HP:0002173)1.71274965
150Azoospermia (HP:0000027)1.71116594
151Abnormal delivery (HP:0001787)1.70736907
152Ankyloglossia (HP:0010296)1.70471414
153Entropion (HP:0000621)1.69365919
154Redundant skin (HP:0001582)1.68843797
155Small intestinal stenosis (HP:0012848)1.66736657
156Duodenal stenosis (HP:0100867)1.66736657
157Breast carcinoma (HP:0003002)1.66214657
158Follicular hyperkeratosis (HP:0007502)1.66146649
159Abnormal foot bone ossification (HP:0010675)1.64975911
160Pili torti (HP:0003777)1.64499381
161Renal duplication (HP:0000075)1.64339655
162Aplasia/hypoplasia of the humerus (HP:0006507)1.64283876
163Missing ribs (HP:0000921)1.64076288
164Capillary hemangiomas (HP:0005306)1.63984085
165Back pain (HP:0003418)1.63697818
166Rhabdomyosarcoma (HP:0002859)1.60818848
167Uterine neoplasm (HP:0010784)1.60533114
168Generalized amyotrophy (HP:0003700)1.59894560
169Absent forearm bone (HP:0003953)1.59725704
170Aplasia involving forearm bones (HP:0009822)1.59725704
171Natal tooth (HP:0000695)1.58903863
172Abnormality of the carotid arteries (HP:0005344)1.57459521
173Testicular atrophy (HP:0000029)1.57058425
174Abnormality of oral frenula (HP:0000190)1.56829603
175Poikiloderma (HP:0001029)1.55778257
176Aplasia/Hypoplasia of the sacrum (HP:0008517)1.55588639
177Abnormal tarsal ossification (HP:0008369)1.53216413
178Short humerus (HP:0005792)1.53003438

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.11786909
2EIF2AK14.01211679
3STK163.80258072
4WEE13.69959725
5BCKDK3.69180680
6ACVR1B2.96059381
7NME22.95824598
8EIF2AK32.70215913
9PLK42.34416509
10BRSK22.14027772
11PAK41.98977004
12MAP3K121.84518192
13AKT31.83569645
14SRPK11.83011873
15EPHA21.82713569
16VRK21.75568187
17TSSK61.74315175
18NEK91.73837518
19IRAK31.64328457
20STK38L1.52715236
21DYRK31.50487109
22TTK1.49342398
23PLK11.48596205
24TAF11.46402363
25NEK21.46239169
26MKNK21.44743392
27PIM21.40568486
28TAOK31.39578859
29EEF2K1.38043046
30SMG11.35772438
31PIK3CG1.33975776
32RPS6KA41.32607934
33MAP3K31.32060581
34BRAF1.30311120
35CDC71.29800073
36PDGFRA1.29128528
37ERBB41.28541433
38VRK11.28443102
39PKN21.25594673
40PLK31.22504340
41PTK21.19820638
42TRIB31.19258510
43PBK1.17083670
44FLT31.14207196
45PDK31.12685647
46PDK41.12685647
47ABL21.11925406
48TRIM281.09724852
49AURKB1.09168651
50TESK21.08675817
51PDK21.08122908
52ARAF1.06902776
53NEK11.03059530
54MKNK11.01482267
55CDK121.00900082
56TESK10.98250599
57LATS10.94009569
58ZAK0.93915379
59LIMK10.93167854
60MYLK0.92660833
61FGFR40.91024746
62ERN10.89065793
63FRK0.88776581
64CDK70.87960348
65NUAK10.85439623
66ILK0.85189698
67MAP3K90.84911746
68EIF2AK20.83555709
69PAK20.82245908
70KDR0.81032012
71STK390.80959391
72CHEK20.79857754
73AURKA0.77651064
74IRAK40.77171527
75MAPK110.76655564
76BRSK10.75886876
77FGFR10.75810131
78PINK10.75019875
79NLK0.74691750
80CSNK2A10.74595072
81BCR0.72523046
82CDK40.70135235
83MAP3K80.69939208
84TLK10.69697586
85ERBB30.69483076
86ICK0.69391085
87MAP2K30.67748105
88PIM10.66368626
89CSNK2A20.65355527
90STK30.64202354
91MST1R0.64099877
92STK240.63031727
93PASK0.61682226
94MST40.59041635
95CSNK1G10.57992379
96ATR0.57422439
97ALK0.57418593
98NME10.56995751
99MAP3K110.54675216
100RPS6KB20.54327145
101CSNK1G30.53530739
102ZAP700.53125935
103TYK20.52782022
104AKT20.49910820
105MELK0.49848149
106TEC0.49718894
107DMPK0.48168603
108SIK10.47648813
109PRKCI0.47318531
110LMTK20.47186715
111CDK80.46495714
112SCYL20.45889615
113TXK0.44408954
114CHEK10.43738029
115CCNB10.43695450
116MTOR0.43349767
117PNCK0.42630053
118STK100.41763367
119DYRK20.41277223
120CDK60.41261848
121CSNK1E0.41035423
122CDK10.39439182
123MAP3K100.38769567
124CLK10.38638418
125MAP2K20.35155504
126STK40.35128954
127NEK60.34981812
128GRK10.34967007
129TTN0.34473112
130RPS6KB10.32902515
131IRAK10.31805936
132PTK60.31388070
133MET0.30509190
134ATM0.30478794
135LATS20.30211830
136TGFBR10.30179562
137MAP3K50.29600586
138MAPK150.27918595
139PAK10.27489054

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.12632842
2Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.86251502
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.59320439
4Vitamin B6 metabolism_Homo sapiens_hsa007502.57132893
5Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.46468843
6Folate biosynthesis_Homo sapiens_hsa007902.28390535
7Drug metabolism - other enzymes_Homo sapiens_hsa009832.09912802
8Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.09846138
9Pentose and glucuronate interconversions_Homo sapiens_hsa000402.04939310
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.04622178
11Arginine biosynthesis_Homo sapiens_hsa002201.98588006
12Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.96017309
13Proteasome_Homo sapiens_hsa030501.93522452
14Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.90914734
15Tryptophan metabolism_Homo sapiens_hsa003801.87858210
16RNA polymerase_Homo sapiens_hsa030201.83693970
17Nitrogen metabolism_Homo sapiens_hsa009101.82514334
18Selenocompound metabolism_Homo sapiens_hsa004501.79903121
19Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.78051922
20Complement and coagulation cascades_Homo sapiens_hsa046101.77257043
21One carbon pool by folate_Homo sapiens_hsa006701.74486805
22Cysteine and methionine metabolism_Homo sapiens_hsa002701.70583946
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.69965682
24Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.68650405
25Peroxisome_Homo sapiens_hsa041461.64842856
26Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.63010520
27Fatty acid degradation_Homo sapiens_hsa000711.62985287
28Chemical carcinogenesis_Homo sapiens_hsa052041.58569086
29DNA replication_Homo sapiens_hsa030301.55370136
30Histidine metabolism_Homo sapiens_hsa003401.51747894
31Protein export_Homo sapiens_hsa030601.49400454
32Steroid hormone biosynthesis_Homo sapiens_hsa001401.46776320
33Pyrimidine metabolism_Homo sapiens_hsa002401.44132160
34Retinol metabolism_Homo sapiens_hsa008301.43118805
35Sulfur metabolism_Homo sapiens_hsa009201.41685652
36Butanoate metabolism_Homo sapiens_hsa006501.40809124
37Biosynthesis of amino acids_Homo sapiens_hsa012301.40445712
38Propanoate metabolism_Homo sapiens_hsa006401.39450552
39Sulfur relay system_Homo sapiens_hsa041221.37227968
40Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.36448966
41beta-Alanine metabolism_Homo sapiens_hsa004101.36212504
42Caffeine metabolism_Homo sapiens_hsa002321.34320657
43Maturity onset diabetes of the young_Homo sapiens_hsa049501.33482634
44Ribosome_Homo sapiens_hsa030101.32005517
45Mismatch repair_Homo sapiens_hsa034301.30215668
46mRNA surveillance pathway_Homo sapiens_hsa030151.23445977
47Cyanoamino acid metabolism_Homo sapiens_hsa004601.22666534
48Thyroid cancer_Homo sapiens_hsa052161.20998469
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.19786031
50RNA transport_Homo sapiens_hsa030131.17279512
51Vitamin digestion and absorption_Homo sapiens_hsa049771.17107223
52N-Glycan biosynthesis_Homo sapiens_hsa005101.15548396
53Phenylalanine metabolism_Homo sapiens_hsa003601.15181420
54Glutathione metabolism_Homo sapiens_hsa004801.13698203
55Carbon metabolism_Homo sapiens_hsa012001.12585596
56Arginine and proline metabolism_Homo sapiens_hsa003301.11444932
57Steroid biosynthesis_Homo sapiens_hsa001001.07799879
58Nucleotide excision repair_Homo sapiens_hsa034201.06208656
59Tyrosine metabolism_Homo sapiens_hsa003501.05869842
60Fatty acid elongation_Homo sapiens_hsa000621.05808351
61Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.04219090
62Pentose phosphate pathway_Homo sapiens_hsa000301.03659208
63Fatty acid metabolism_Homo sapiens_hsa012121.00581669
64PPAR signaling pathway_Homo sapiens_hsa033200.99982587
65Pyruvate metabolism_Homo sapiens_hsa006200.97204302
66* Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.95843226
67Hippo signaling pathway_Homo sapiens_hsa043900.95500058
68Central carbon metabolism in cancer_Homo sapiens_hsa052300.95197823
69Fat digestion and absorption_Homo sapiens_hsa049750.93175920
70Adherens junction_Homo sapiens_hsa045200.91430316
71TGF-beta signaling pathway_Homo sapiens_hsa043500.90322179
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.89742537
73Starch and sucrose metabolism_Homo sapiens_hsa005000.89422502
74Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.89075001
75Staphylococcus aureus infection_Homo sapiens_hsa051500.87254281
76Basal transcription factors_Homo sapiens_hsa030220.86677836
77Homologous recombination_Homo sapiens_hsa034400.85179575
78Base excision repair_Homo sapiens_hsa034100.84667678
79Spliceosome_Homo sapiens_hsa030400.82652091
80Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82175798
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78747184
82Metabolic pathways_Homo sapiens_hsa011000.75123859
83Regulation of autophagy_Homo sapiens_hsa041400.71197158
84Bladder cancer_Homo sapiens_hsa052190.69888169
85Purine metabolism_Homo sapiens_hsa002300.69157925
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.69101028
87Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66824661
88Small cell lung cancer_Homo sapiens_hsa052220.65756544
89Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.65626421
90Proteoglycans in cancer_Homo sapiens_hsa052050.65314982
91Cell cycle_Homo sapiens_hsa041100.64086971
92ECM-receptor interaction_Homo sapiens_hsa045120.63151423
93Fructose and mannose metabolism_Homo sapiens_hsa000510.62305729
94RNA degradation_Homo sapiens_hsa030180.62119885
95Oocyte meiosis_Homo sapiens_hsa041140.61905223
96Bile secretion_Homo sapiens_hsa049760.56874610
97Tight junction_Homo sapiens_hsa045300.56740733
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56650334
99Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.56193137
100MicroRNAs in cancer_Homo sapiens_hsa052060.55535494
101ABC transporters_Homo sapiens_hsa020100.53786468
102Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.52491064
103Linoleic acid metabolism_Homo sapiens_hsa005910.50141764
104Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.50008469
105Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.49450727
106Fanconi anemia pathway_Homo sapiens_hsa034600.49187993
107Fatty acid biosynthesis_Homo sapiens_hsa000610.47182853
108Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.46763125
109Glycerolipid metabolism_Homo sapiens_hsa005610.46585768
110Galactose metabolism_Homo sapiens_hsa000520.44680050
111Non-homologous end-joining_Homo sapiens_hsa034500.43467861
112Focal adhesion_Homo sapiens_hsa045100.42323368
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40962769
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39254267
115p53 signaling pathway_Homo sapiens_hsa041150.39142862
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36477423
117Sphingolipid metabolism_Homo sapiens_hsa006000.36444394
118Prostate cancer_Homo sapiens_hsa052150.36093161
119Wnt signaling pathway_Homo sapiens_hsa043100.35274371
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.34466905
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.33951082
122Arachidonic acid metabolism_Homo sapiens_hsa005900.29398893
123Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.21979130
124Lysine degradation_Homo sapiens_hsa003100.20120826
125Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.13459353

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »